Sweroside (BioDeep_00000000081)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


(3S,4R,4aS)-4-ethenyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,4a,5,6-tetrahydro-3H-pyrano[3,4-c]pyran-8-one

化学式: C16H22O9 (358.1263762)
中文名称: 獐牙菜苷
谱图信息: 最多检出来源 Viridiplantae(plant) 0.59%

Reviewed

Last reviewed on 2024-10-24.

Cite this Page

Sweroside. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/sweroside (retrieved 2024-11-08) (BioDeep RN: BioDeep_00000000081). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C=CC1C(OC2OC(CO)C(O)C(O)C2O)OC=C2C(=O)OCCC21
InChI: InChI=1S/C16H22O9/c1-2-7-8-3-4-22-14(21)9(8)6-23-15(7)25-16-13(20)12(19)11(18)10(5-17)24-16/h2,6-8,10-13,15-20H,1,3-5H2/t7-,8+,10-,11-,12+,13-,15+,16+/m1/s1

描述信息

Sweroside is a glycoside.
Sweroside is a natural product found in Strychnos axillaris, Lonicera japonica, and other organisms with data available.
See also: Lonicera japonica flower (part of); Menyanthes trifoliata leaf (part of); Centaurium erythraea whole (part of).
Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect[1][2].
Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect[1][2].

同义名列表

17 个代谢物同义名

InChI=1/C16H22O9/c1-2-7-8-3-4-22-14(21)9(8)6-23-15(7)25-16-13(20)12(19)11(18)10(5-17)24-16/h2,6-8,10-13,15-20H,1,3-5H2/t7-,8+,10-,11-,12+,13-,15+,16+/m1/s1; (3S,4R,4aS)-4-ethenyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,4a,5,6-tetrahydro-3H-pyrano[3,4-c]pyran-8-one; 1H,3H-PYRANO(3,4-C)PYRAN-1-ONE, 5-ETHENYL-6-(.BETA.-D-GLUCOPYRANOSYLOXY)-4,4A,5,6-TETRAHYDRO-, (4AS-(4A.ALPHA.,5.BETA.,6.ALPHA.))-; 1H,3H-Pyrano(3,4-c)pyran-1-one, 5-ethenyl-6-(beta-D-glucopyranosyloxy)-4,4a,5,6-tetrahydro-, (4aS-(4aalpha,5beta,6alpha))-; 1H,3H-PYRANO(3,4-C)PYRAN-1-ONE, 5-ETHENYL-6-(.BETA.-D-GLUCOPYRANOSYLOXY)-4,4A,5,6-TETRAHYDRO-, (4AS,5R,6S)-; 1H,3H-PYRANO(3,4-C)PYRAN-1-ONE, 5-ETHENYL-6-(beta-D-GLUCOPYRANOSYLOXY)-4,4A,5,6-TETRAHYDRO-, (4AS,5R,6S)-; Sweroside, >=95\\% (LC/MS-ELSD); 1,9-trans-9,5-cis-sweroside; UNII-I3YG76417O; MEGxp0_000813; (-)-Sweroside; ACon1_000233; ACon0_001457; I3YG76417O; Sweroside; NCGC00180755-03_C16H22O9_(4aS,5R,6S)-1-Oxo-5-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-6-yl beta-D-glucopyranoside; LS-14516



数据库引用编号

38 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

304 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yan Ding, Yuefu Chen, Ke Hu, Qiansheng Yang, Yuxian Li, Minjiang Huang. Sweroside alleviates hepatic steatosis in part by activating AMPK/mTOR-mediated autophagy in mice. Journal of cellular biochemistry. 2023 Jun; ?(?):. doi: 10.1002/jcb.30428. [PMID: 37269482]
  • Gokhan Zengin, Mohamed El-Raey, Walaa El-Kashak, Gaber El-Saber Batiha, Duaa Althumairy, Sarah Alamer, Nada M Mostafa, Omayma A Eldahshan. Sweroside: An iridoid glycoside of potential neuroprotective, antidiabetic, and antioxidant activities supported by molecular docking. Amino acids. 2023 Mar; ?(?):. doi: 10.1007/s00726-023-03262-9. [PMID: 36939919]
  • Ion Brinza, Mohamed A El Raey, Walaa El-Kashak, Omayma A Eldahshan, Lucian Hritcu. Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (Danio rerio) Model: Involvement of Cholinergic System and Brain Oxidative Stress. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27185901. [PMID: 36144637]
  • Poomraphie Nuntawong, Taiki Horikawa, Hiroyuki Tanaka, Satoshi Morimoto, Seiichi Sakamoto. Activated Carbon-Based Immunochromatographic Strip Test for the Rapid Qualitative Analysis of Swertiamarin and Sweroside. Journal of AOAC International. 2022 Sep; 105(5):1460-1467. doi: 10.1093/jaoacint/qsac054. [PMID: 35521980]
  • Juan Wang, Xiaolan Cai, Rui Ma, Dapeng Lei, Xinliang Pan, Fengshan Wang. Anti-inflammatory Effects of Sweroside on LPS-Induced ALI in Mice Via Activating SIRT1. Inflammation. 2021 Oct; 44(5):1961-1968. doi: 10.1007/s10753-021-01473-4. [PMID: 33913051]
  • Syed Mudassir Jeelani, Jasvinder Singh, Arti Sharma, Gulzar A Rather, Sheikh Abid Ali, Ajai Prakash Gupta, Shashank Singh, Surrinder K Lattoo. In-vitro cytotoxicity in relation to chemotypic diversity in diploid and tetraploid populations of Gentiana kurroo Royle. Journal of ethnopharmacology. 2021 Jun; 274(?):113966. doi: 10.1016/j.jep.2021.113966. [PMID: 33647427]
  • Qiaoling Yang, Fangfang Shu, Junting Gong, Ping Ding, Rongrong Cheng, Jinmei Li, Renchao Tong, Lili Ding, Huajun Sun, Wendong Huang, Zhengtao Wang, Li Yang. Sweroside ameliorates NAFLD in high-fat diet induced obese mice through the regulation of lipid metabolism and inflammatory response. Journal of ethnopharmacology. 2020 Jun; 255(?):112556. doi: 10.1016/j.jep.2020.112556. [PMID: 31926984]
  • Gabsik Yang, Joo Hyeon Jang, Sung Wook Kim, Sin-Hee Han, Kyung-Ho Ma, Jae-Ki Jang, Han Chang Kang, Yong-Yeon Cho, Hye Suk Lee, Joo Young Lee. Sweroside Prevents Non-Alcoholic Steatohepatitis by Suppressing Activation of the NLRP3 Inflammasome. International journal of molecular sciences. 2020 Apr; 21(8):. doi: 10.3390/ijms21082790. [PMID: 32316419]
  • Yuangui Yang, Yanli Zhao, Zhitian Zuo, Ji Zhang, Yao Shi, Yuanzhong Wang. Investigation of a Medical Plant for Hepatic Diseases with Secoiridoids Using HPLC and FT-IR Spectroscopy for a Case of Gentiana rigescens. Molecules (Basel, Switzerland). 2020 Mar; 25(5):. doi: 10.3390/molecules25051219. [PMID: 32182739]
  • Qing-Chang Wu, Xi-Yang Tang, Zi-Qin Dai, Yi Dai, Hui-Hui Xiao, Xin-Sheng Yao. Sweroside promotes osteoblastic differentiation and mineralization via interaction of membrane estrogen receptor-α and GPR30 mediated p38 signalling pathway on MC3T3-E1 cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Mar; 68(?):153146. doi: 10.1016/j.phymed.2019.153146. [PMID: 32028183]
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  • Junting Gong, Fan Yang, Qiaoling Yang, Xiaowen Tang, Fangfang Shu, Lieming Xu, Zhengtao Wang, Li Yang. Sweroside ameliorated carbon tetrachloride (CCl4)-induced liver fibrosis through FXR-miR-29a signaling pathway. Journal of natural medicines. 2020 Jan; 74(1):17-25. doi: 10.1007/s11418-019-01334-3. [PMID: 31280460]
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  • Rui Wang, Zhaoyue Dong, Xiaozhong Lan, Zhihua Liao, Min Chen. Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells. Molecules (Basel, Switzerland). 2019 Mar; 24(5):. doi: 10.3390/molecules24050872. [PMID: 30823686]
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  • Xian-Ju Huang, Jun Li, Zhi-Yi Mei, Guoxun Chen. Gentiopicroside and sweroside from Veratrilla baillonii Franch. induce phosphorylation of Akt and suppress Pck1 expression in hepatoma cells. Biochemistry and cell biology = Biochimie et biologie cellulaire. 2016 06; 94(3):270-8. doi: 10.1139/bcb-2015-0173. [PMID: 27248905]
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