Crustecdysone (BioDeep_00000002779)

Secondary id: BioDeep_00000171790, BioDeep_00000407045, BioDeep_00000410545

human metabolite PANOMIX_OTCML-2023 Endogenous

代谢物信息卡片

(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]phenanthren-6-one

化学式: C27H44O7 (480.3086874)
中文名称: β-蜕皮甾酮, β-蜕皮激素, 蜕皮激素, 蜕皮激素
谱图信息: 最多检出来源 Macaca mulatta(otcml) 0.04%

分子结构信息

SMILES: C1[C@H](O)[C@H](O)C[C@@]2([H])C(=O)C=C3[C@@](CC[C@]4([C@@]3(O)CC[C@]4([H])[C@](O)(C)[C@H](O)CCC(O)(C)C)C)([H])[C@]21C
InChI: InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1

描述信息

20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related to an ecdysone.
20-Hydroxyecdysone is a natural product found in Asparagus filicinus, Trichobilharzia ocellata, and other organisms with data available.
A steroid hormone that regulates the processes of MOLTING or ecdysis in insects. Ecdysterone is the 20-hydroxylated ECDYSONE.
Crustecdysone is found in crustaceans. Crustecdysone is isolated from the marine crayfish Jasus lalandei in low yield (2 mg/ton
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.
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Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1]. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2]. Crustecdysone is an active metabolite of Ecdysone (HY-N0179)[3].
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1]. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2]. Crustecdysone is an active metabolite of Ecdysone (HY-N0179)[3].

同义名列表

73 个代谢物同义名

(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-((2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-6H-cyclopenta[a]phenanthren-6-one; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; (2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(1R,2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one; (1R,2R,4S,5R,7R,11S,14S,15R)-4,5,11-trihydroxy-2,15-dimethyl-14-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-9-en-8-one; 2,3,14-Trihydroxy-10,13-dimethyl-17-(1,2,5-trihydroxy-1,5-dimethyl-hexyl)-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one; Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2.beta.,3.beta.,5.beta.,22R)-; Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2-beta,3-beta,5-beta,22R)-; Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2beta,3beta,5beta,22R)-; 5-beta-Cholest-7-en-6-one, 2-beta,3-beta,14,20,22,25-hexahydroxy-, (22R)-; (2alpha,3alpha,5alpha,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one; (22R)-2beta,3beta,14alpha,20,22,25-hexahydroxy-5beta-cholest-7-en-6-one; (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one; 2beta,3beta,14alpha,20R,22R,25-hexahydroxy-5beta-cholest-7-en-6-one; 2beta,3beta,14alpha,20beta,22alpha,25-Hexahydroxycholest-7-en-6-one; 2beta,3beta,14alpha,20,22R,25-hexahydroxy-5beta-cholest-7-en-6-one; Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2b,3b,5b,22R)-; (2Beta,3beta,5beta)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one; 2-beta,3-beta,14,20,22,25-Hexahydroxy-5-beta-cholet-7-en-6- one; 2-beta,3-beta,14,20,22,25-Hexahydroxy-5-beta-cholet-7-en-6-one; (2b,3b,5b,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one; (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one; 2β,3β,14α,20β,22α,25-Hexahydroxycholest-7-en-6-one; 20-Hydroxyecdysone, >=93\\% (HPLC), powder; 20-HYDROXY-.ALPHA.-ECDYSONE; 20-HYDROXYECDYSONE [WHO-DD]; NKDFYOWSKOHCCO-YPVLXUMRSA-N; 20-Hydroxy-alpha-ecdysone; 20-HYDROXYECDYSONE [MI]; B-ecdysone,Commisterone; (+)-20-Hydroxyecdysone; 20-Hydroxy-a-ecdysone; 20-Hydroxy-α-ecdysone; 20R-Hydroxyecdysone; 20 Hydroxyecdysone; 20-Hydroxyecdysone; 20-Hydroxyecdyson; .beta-Ecdysterone; beta-ECDYSTERONE; Isoinokosterone; Hydroxyecdysone; (+)-Ecdysterone; beta-Ecydisone; 20-OH ecdysone; beta-Ecdysone; b-Ecdysterone; Crustecdysone; beta-Ecdisone; Beta Ecdysone; Viticosterone; β-Ecdysterone; Crustecdyson; Commisterone; Polypodine A; Polypodine C; Polypodin C; Ecdysterone; Polypodin A; β-Ecydisone; ?- Ecdysone; ST 27:2;O7; b-Ecdysone; Edysterone; Ecdysteron; Β-ecdysone; AI3-44727; Ecdystene; Sarconeos; Ecdysten; Ekdisten; THE-7; 20-E; 20E; (2S,3R,5R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one

数据库引用编号

24 个数据库交叉引用编号

ChEBI: CHEBI:16587
KEGG: C02633
PubChem: 5459840
PubChem: 271605
PubChem: 439770
HMDB: HMDB0030180
DrugBank: DB16935
ChEMBL: CHEMBL224128
Wikipedia: 20-Hydroxyecdysone
LipidMAPS: LMST01010209
MeSH: Ecdysterone
ChemIDplus: 0005289747
MetaCyc: CPD-276
KNApSAcK: C00003654
KNApSAcK: C00048286
chemspider: 4573597
CAS: 5289-74-7
medchemexpress: HY-N6979
PMhub: MS000004946
MetaboLights: MTBLC16587
PubChem: 5613
PDB-CCD: 20E
3DMET: B04858
NIKKAJI: J13.425B

分类词条

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(1)

Molting Hormone Biosynthesis: Cholesterol + Hydrogen Ion + NADH + Oxygen ⟶ 7-Dehydrocholesterol + NAD + Water

PharmGKB(0)

339 个相关的物种来源信息

33090 珍珠露水草: -
65004 Serratula tinctoria:
3562 Spinacia oleracea:
38596 Ajuga reptans:
7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
305371 Klasea erucifolia:
354317 Klasea procumbens: 10.1007/BF00574363
37657 Silene latifolia: 10.1007/BF00574363
1937749 Silene brahuica:
231488 Paris quadrifolia: 10.1007/BF00574363
7091 Bombyx mori:
2082040 Silene wallichiana:
362639 Rhaponticum lyratum: 10.1007/BF00574363
362636 Rhaponticum integrifolium:
305379 Klasea quinquefolia: 10.1007/BF00574363
305367 Klasea centauroides: 10.1007/BF00574363
362630 Rhaponticum carthamoides:
354313 Klasea marginata: 10.1007/BF00574363
354320 Klasea sogdiana: 10.1007/BF00574363
335148 Silene viridiflora:
42039 Silene otites:
1729754 Poranopsis discifera: 10.1016/0039-128X(76)90006-4
7010 Schistocerca gregaria: 10.1039/C39810000418
39891 Silene linicola:
42038 Silene nutans:
100515 Asparagus filicinus: 10.1016/S0031-9422(99)00051-5
221254 Paris polyphylla var. chinensis:
49666 Paris polyphylla:
44685 Panax japonicus: 10.1002/HLCA.201100085
548845 Vitex tripinnata: 10.1016/S0031-9422(98)00411-7
80604 Tapinella panuoides: 10.1016/S0031-9422(98)00448-8
72122 Tapinella atrotomentosa:
274375 Nierembergia linariifolia: 10.1016/0031-9422(95)00731-8
144308 Nierembergia hippomanica: 10.1016/0031-9422(95)00731-8
7130 Manduca sexta:
49675 Trillium camschatcense: 10.1248/CPB.55.551
171899 Helleborus purpurascens:
59080 Gagea serotina: 10.1016/S0305-1978(01)00021-7
58048 Polypodium vulgare:
872808 Polypodium virginianum:
2708930 Penianthus zenkeri: 10.1016/0031-9422(91)85047-4
42037 Silene italica: 10.1021/NP0205194
39894 Silene nemoralis: 10.1021/NP0205194
171901 Helleborus torquatus: 10.1016/S0031-9422(01)00070-X
285590 Tinospora cordifolia:
108380 Sida spinosa: 10.1016/S0031-9422(03)00021-9
2364071 Vitex cymosa: 10.1016/S0367-326X(00)00304-X
167472 Stachyurus himalaicus: 10.3390/12030536
362646 Rhaponticum uniflorum:
49702 Blandfordia punicea: 10.1021/NP960377B
105401 Zoanthus: 10.1021/NP010645S
46114 Froelichia floridana:
165205 Afrocarpus gracilior: 10.1016/J.PHYTOL.2012.02.005
50545 Trillium erectum: 10.1016/J.PHYTOCHEM.2008.10.019
548852 Vitex pinnata: 10.1016/S0031-9422(00)94985-9
86683 Woodwardia orientalis: 10.1248/CPB.41.1803
65704 Athyrium yokoscense: 10.1016/0031-9422(95)00688-5
224738 Lepidothamnus intermedius: 10.1071/CH9721935
1503182 Cyanotis arachnoidea: 10.1080/10286020290019631
295252 Agelas dispar:
221775 Gomphrena globosa: 10.1016/S0305-1978(97)00106-3
2528988 Gomphrena cunninghamii: 10.1016/S0305-1978(97)00106-3
2528985 Gomphrena affinis: 10.1016/S0305-1978(97)00106-3
2528987 Gomphrena canescens: 10.1016/S0305-1978(97)00106-3
240061 Gomphrena haageana: 10.1016/S0305-1978(97)00106-3
221778 Gomphrena serrata: 10.1016/S0305-1978(97)00106-3
44924 Parazoanthus:
1899206 Vitex madiensis:
1736745 Ajuga chamaecistus: 10.1016/S0021-9673(01)88168-1
13123 Lymantria dispar: 10.1002/ARCH.940010404
283497 Iotrochota birotulata: 10.1016/S0039-128X(99)00096-3
663359 Silene turkestanica:
4164 Digitalis purpurea: 10.1007/S10600-010-9551-3
2026104 Ajuga iva: 10.1016/S0031-9422(00)97527-7
413480 Vitex canescens:
171898 Helleborus orientalis: 10.1016/J.PHYTOCHEM.2007.11.007
63459 Chenopodium quinoa:
1365883 Vitex megapotamica: 10.1002/ARDP.19723051007
39917 Silene tatarica:
120713 Brainea insignis: 10.1016/J.PHYTOCHEM.2010.03.002
41536 Centaurea melitensis:
41506 Plectocephalus americanus:
1137874 Silene banksia: 10.1007/BF00598381
79782 Cimex lectularius: 10.1007/BF01946477
72517 Arilus cristatus: 10.1007/BF01946477
7536 Oncopeltus fasciatus: 10.1007/BF01946477
29025 Podisus maculiventris: 10.1007/BF01946477
13249 Rhodnius prolixus: 10.1007/BF01946477
191328 Dysdercus cingulatus: 10.1007/BF01946477
85310 Nezara viridula: 10.1007/BF01946477
99806 Taxus cuspidata:
80839 Charybdis japonica: 10.1073/PNAS.86.17.6826
1930050 Sida szechuensis: 10.14233/AJCHEM.2014.15427
461588 Fibraurea tinctoria: 10.1002/PTR.2650070406
527504 Fibraurea chloroleuca: 10.1002/PTR.2650070406
2873767 Haematocarpus subpeltatus: 10.1002/PTR.2650070406
240005 Achyranthes aspera: 10.1007/PL00010306
265172 Penstemon venustus: 10.1016/0031-9422(94)00948-S
90697 Plenasium banksiifolium: 10.1055/S-0028-1097493
28973 Limnanthes douglasii: 10.1016/S0031-9422(96)00591-2
46220 Taxus brevifolia: 10.1016/0031-9422(95)00672-9
49984 Ajuga chamaepitys: 10.1016/S0031-9422(00)84101-1
152357 Diploclisia glaucescens:
171888 Helleborus cyclophyllus: 10.1016/J.JEP.2020.112954
171897 Helleborus odorus:
171903 Helleborus viridis: 10.3109/13880209009082817
221785 Pfaffia glomerata:
82527 Ipheion uniflorum: 10.1248/CPB.42.1116
261975 Pycnogonum litorale: 10.1515/ZNC-1994-5-615
39855 Silene chalcedonica:
1850527 Silene wilfordii: 10.1007/BF00636589
464020 Axyris amaranthoides: 10.1016/S0031-9422(98)00446-4
451963 Pfaffia iresinoides:
376799 Atriplex portulacoides: 10.1016/J.BMCL.2015.03.028
292330 Ourisia macrophylla: 10.1016/S0305-1978(96)00083-X
292327 Ourisia macrocarpa: 10.1016/S0305-1978(96)00083-X
292312 Ourisia caespitosa: 10.1016/S0305-1978(96)00083-X
3553 Atriplex nummularia: 10.1016/S0367-326X(99)00159-8
1309628 Silene supina: 10.1007/BF02254804
2039599 Silene spergulifolia: 10.1007/BF02254804
122298 Blitum bonus-henricus: 10.1016/0031-9422(82)80057-5
46091 Chenopodiastrum murale: 10.1002/(SICI)1520-6327(1999)41:1<18::AID-ARCH4>3.0.CO;2-T
254022 Sagina japonica: 10.1007/S10600-010-9729-8
13824 Lygodium japonicum: 10.1007/S11418-009-0376-Y
100602 Trichobilharzia ocellata: 10.1016/0166-6851(91)90139-W
387932 Anemone montana: 10.1016/S0305-1978(97)00042-2
174168 Anemone occidentalis: 10.1016/S0305-1978(97)00042-2
445234 Anemone pulsatilla: 10.1016/S0305-1978(97)00042-2
470566 Anemone alpina: 10.1016/S0305-1978(97)00042-2
413482 Vitex glabrata: 10.1021/NP50044A041
42439 Limnanthes alba: 10.1515/ZNC-2001-11-1214
82502 Trillium tschonoskii: 10.1248/CPB.17.340
84614 Cyrtomium falcatum: 10.1248/CPB.17.340
984302 Ajuga nipponensis: 10.1248/CPB.17.340
167911 Ajuga decumbens: 10.1248/CPB.17.340
82499 Trillium smallii: 10.1248/CPB.17.340
85277 Stachyurus praecox: 10.1248/CPB.17.340
38391 Polypodium fauriei: 10.1248/CPB.17.340
6535 Cornu aspersum: 10.1007/BF01959769
6526 Biomphalaria glabrata: 10.1007/BF01959769
6523 Lymnaea stagnalis: 10.1007/BF01959769
2709034 Vitex thyrsiflora: 10.1016/S0021-9673(01)90442-X
86596 Palythoa: 10.1007/BF00598556
87477 Trisetum flavescens: 10.1016/S0305-1978(97)00087-2
882375 Chenopodium pallidicaule: 10.1016/0305-1978(96)00019-1
41472 Amberboa moschata: 10.1016/S0305-1978(97)00018-5
3559 Chenopodium album:
6252 Ascaris lumbricoides: 10.1007/BF01923635
362646 Rhaponticum uniflorum: 10.1016/J.PHYTOCHEM.2009.04.008
1080098 Silene indica:
1137874 Silene banksia: 10.1007/BF00574584
411984 Silene fortunei: 10.1007/BF00574584
39894 Silene nemoralis: 10.1007/BF00574584
362630 Rhaponticum carthamoides:
161397 Cistanche tubulosa: 10.1248/CPB.38.1927
87754 Cistanche phelypaea: 10.1248/CPB.38.1927
65004 Serratula tinctoria: 10.1016/S0031-9422(01)00308-9
171901 Helleborus torquatus: 10.1016/J.PHYTOCHEM.2007.11.007
49666 Paris polyphylla: 10.1016/J.FITOTE.2008.09.010
39855 Silene chalcedonica: 10.1007/BF00636590
253767 Neocheiropteris palmatopedata: 10.1007/S10600-010-9560-2
384659 Achyranthes bidentata: 10.1016/0040-4020(76)80160-3
152356 Diploclisia: 10.1055/S-2007-969388
32101 Pteridium aquilinum: 10.1016/S0031-9422(00)89065-2
699700 Lepisorus ussuriensis: 10.1016/S0031-9422(99)00056-4
295252 Agelas dispar: 10.1021/NP970323H
63459 Chenopodium quinoa: 10.1021/JF0014462
42037 Silene italica: 10.1021/NP0205194
65004 Serratula tinctoria:
3562 Spinacia oleracea:
38596 Ajuga reptans:
7461 Apis cerana: 10.1371/JOURNAL.PONE.0175573
305371 Klasea erucifolia:
354317 Klasea procumbens: 10.1007/BF00574363
37657 Silene latifolia: 10.1007/BF00574363
1937749 Silene brahuica:
231488 Paris quadrifolia: 10.1007/BF00574363
7091 Bombyx mori:
2082040 Silene wallichiana:
362639 Rhaponticum lyratum: 10.1007/BF00574363
362636 Rhaponticum integrifolium:
305379 Klasea quinquefolia: 10.1007/BF00574363
305367 Klasea centauroides: 10.1007/BF00574363
362630 Rhaponticum carthamoides:
354313 Klasea marginata: 10.1007/BF00574363
354320 Klasea sogdiana: 10.1007/BF00574363
335148 Silene viridiflora:
42039 Silene otites:
1729754 Poranopsis discifera: 10.1016/0039-128X(76)90006-4
7010 Schistocerca gregaria: 10.1039/C39810000418
39891 Silene linicola:
42038 Silene nutans:
100515 Asparagus filicinus: 10.1016/S0031-9422(99)00051-5
221254 Paris polyphylla var. chinensis:
49666 Paris polyphylla:
44685 Panax japonicus: 10.1002/HLCA.201100085
548845 Vitex tripinnata: 10.1016/S0031-9422(98)00411-7
80604 Tapinella panuoides: 10.1016/S0031-9422(98)00448-8
72122 Tapinella atrotomentosa:
274375 Nierembergia linariifolia: 10.1016/0031-9422(95)00731-8
144308 Nierembergia hippomanica: 10.1016/0031-9422(95)00731-8
7130 Manduca sexta:
49675 Trillium camschatcense: 10.1248/CPB.55.551
171899 Helleborus purpurascens:
59080 Gagea serotina: 10.1016/S0305-1978(01)00021-7
58048 Polypodium vulgare:
872808 Polypodium virginianum:
2708930 Penianthus zenkeri: 10.1016/0031-9422(91)85047-4
42037 Silene italica: 10.1021/NP0205194
39894 Silene nemoralis: 10.1021/NP0205194
171901 Helleborus torquatus: 10.1016/S0031-9422(01)00070-X
285590 Tinospora cordifolia:
108380 Sida spinosa: 10.1016/S0031-9422(03)00021-9
2364071 Vitex cymosa: 10.1016/S0367-326X(00)00304-X
167472 Stachyurus himalaicus: 10.3390/12030536
362646 Rhaponticum uniflorum:
49702 Blandfordia punicea: 10.1021/NP960377B
105401 Zoanthus: 10.1021/NP010645S
46114 Froelichia floridana:
165205 Afrocarpus gracilior: 10.1016/J.PHYTOL.2012.02.005
50545 Trillium erectum: 10.1016/J.PHYTOCHEM.2008.10.019
548852 Vitex pinnata: 10.1016/S0031-9422(00)94985-9
86683 Woodwardia orientalis: 10.1248/CPB.41.1803
65704 Athyrium yokoscense: 10.1016/0031-9422(95)00688-5
224738 Lepidothamnus intermedius: 10.1071/CH9721935
1503182 Cyanotis arachnoidea: 10.1080/10286020290019631
295252 Agelas dispar:
221775 Gomphrena globosa: 10.1016/S0305-1978(97)00106-3
2528988 Gomphrena cunninghamii: 10.1016/S0305-1978(97)00106-3
2528985 Gomphrena affinis: 10.1016/S0305-1978(97)00106-3
2528987 Gomphrena canescens: 10.1016/S0305-1978(97)00106-3
240061 Gomphrena haageana: 10.1016/S0305-1978(97)00106-3
221778 Gomphrena serrata: 10.1016/S0305-1978(97)00106-3
44924 Parazoanthus:
1899206 Vitex madiensis:
1736745 Ajuga chamaecistus: 10.1016/S0021-9673(01)88168-1
13123 Lymantria dispar: 10.1002/ARCH.940010404
283497 Iotrochota birotulata: 10.1016/S0039-128X(99)00096-3
663359 Silene turkestanica:
4164 Digitalis purpurea: 10.1007/S10600-010-9551-3
2026104 Ajuga iva: 10.1016/S0031-9422(00)97527-7
413480 Vitex canescens:
171898 Helleborus orientalis: 10.1016/J.PHYTOCHEM.2007.11.007
63459 Chenopodium quinoa:
1365883 Vitex megapotamica: 10.1002/ARDP.19723051007
39917 Silene tatarica:
120713 Brainea insignis: 10.1016/J.PHYTOCHEM.2010.03.002
41536 Centaurea melitensis:
41506 Plectocephalus americanus:
1137874 Silene banksia: 10.1007/BF00598381
79782 Cimex lectularius: 10.1007/BF01946477
72517 Arilus cristatus: 10.1007/BF01946477
7536 Oncopeltus fasciatus: 10.1007/BF01946477
29025 Podisus maculiventris: 10.1007/BF01946477
13249 Rhodnius prolixus: 10.1007/BF01946477
191328 Dysdercus cingulatus: 10.1007/BF01946477
85310 Nezara viridula: 10.1007/BF01946477
99806 Taxus cuspidata:
80839 Charybdis japonica: 10.1073/PNAS.86.17.6826
1930050 Sida szechuensis: 10.14233/AJCHEM.2014.15427
461588 Fibraurea tinctoria: 10.1002/PTR.2650070406
527504 Fibraurea chloroleuca: 10.1002/PTR.2650070406
2873767 Haematocarpus subpeltatus: 10.1002/PTR.2650070406
240005 Achyranthes aspera: 10.1007/PL00010306
265172 Penstemon venustus: 10.1016/0031-9422(94)00948-S
90697 Plenasium banksiifolium: 10.1055/S-0028-1097493
28973 Limnanthes douglasii: 10.1016/S0031-9422(96)00591-2
46220 Taxus brevifolia: 10.1016/0031-9422(95)00672-9
49984 Ajuga chamaepitys: 10.1016/S0031-9422(00)84101-1
152357 Diploclisia glaucescens:
171888 Helleborus cyclophyllus: 10.1016/J.JEP.2020.112954
171897 Helleborus odorus:
171903 Helleborus viridis: 10.3109/13880209009082817
221785 Pfaffia glomerata:
82527 Ipheion uniflorum: 10.1248/CPB.42.1116
261975 Pycnogonum litorale: 10.1515/ZNC-1994-5-615
39855 Silene chalcedonica:
1850527 Silene wilfordii: 10.1007/BF00636589
464020 Axyris amaranthoides: 10.1016/S0031-9422(98)00446-4
451963 Pfaffia iresinoides:
376799 Atriplex portulacoides: 10.1016/J.BMCL.2015.03.028
292330 Ourisia macrophylla: 10.1016/S0305-1978(96)00083-X
292327 Ourisia macrocarpa: 10.1016/S0305-1978(96)00083-X
292312 Ourisia caespitosa: 10.1016/S0305-1978(96)00083-X
3553 Atriplex nummularia: 10.1016/S0367-326X(99)00159-8
1309628 Silene supina: 10.1007/BF02254804
2039599 Silene spergulifolia: 10.1007/BF02254804
122298 Blitum bonus-henricus: 10.1016/0031-9422(82)80057-5
46091 Chenopodiastrum murale: 10.1002/(SICI)1520-6327(1999)41:1<18::AID-ARCH4>3.0.CO;2-T
254022 Sagina japonica: 10.1007/S10600-010-9729-8
13824 Lygodium japonicum: 10.1007/S11418-009-0376-Y
100602 Trichobilharzia ocellata: 10.1016/0166-6851(91)90139-W
387932 Anemone montana: 10.1016/S0305-1978(97)00042-2
174168 Anemone occidentalis: 10.1016/S0305-1978(97)00042-2
445234 Anemone pulsatilla: 10.1016/S0305-1978(97)00042-2
470566 Anemone alpina: 10.1016/S0305-1978(97)00042-2
413482 Vitex glabrata: 10.1021/NP50044A041
42439 Limnanthes alba: 10.1515/ZNC-2001-11-1214
82502 Trillium tschonoskii: 10.1248/CPB.17.340
84614 Cyrtomium falcatum: 10.1248/CPB.17.340
984302 Ajuga nipponensis: 10.1248/CPB.17.340
167911 Ajuga decumbens: 10.1248/CPB.17.340
82499 Trillium smallii: 10.1248/CPB.17.340
85277 Stachyurus praecox: 10.1248/CPB.17.340
38391 Polypodium fauriei: 10.1248/CPB.17.340
6535 Cornu aspersum: 10.1007/BF01959769
6526 Biomphalaria glabrata: 10.1007/BF01959769
6523 Lymnaea stagnalis: 10.1007/BF01959769
2709034 Vitex thyrsiflora: 10.1016/S0021-9673(01)90442-X
86596 Palythoa: 10.1007/BF00598556
87477 Trisetum flavescens: 10.1016/S0305-1978(97)00087-2
882375 Chenopodium pallidicaule: 10.1016/0305-1978(96)00019-1
41472 Amberboa moschata: 10.1016/S0305-1978(97)00018-5
3559 Chenopodium album:
6252 Ascaris lumbricoides: 10.1007/BF01923635
362646 Rhaponticum uniflorum: 10.1016/J.PHYTOCHEM.2009.04.008
1080098 Silene indica:
1137874 Silene banksia: 10.1007/BF00574584
411984 Silene fortunei: 10.1007/BF00574584
39894 Silene nemoralis: 10.1007/BF00574584
362630 Rhaponticum carthamoides:
161397 Cistanche tubulosa: 10.1248/CPB.38.1927
87754 Cistanche phelypaea: 10.1248/CPB.38.1927
65004 Serratula tinctoria: 10.1016/S0031-9422(01)00308-9
171901 Helleborus torquatus: 10.1016/J.PHYTOCHEM.2007.11.007
49666 Paris polyphylla: 10.1016/J.FITOTE.2008.09.010
39855 Silene chalcedonica: 10.1007/BF00636590
253767 Neocheiropteris palmatopedata: 10.1007/S10600-010-9560-2
384659 Achyranthes bidentata: 10.1016/0040-4020(76)80160-3
152356 Diploclisia: 10.1055/S-2007-969388
32101 Pteridium aquilinum: 10.1016/S0031-9422(00)89065-2
699700 Lepisorus ussuriensis: 10.1016/S0031-9422(99)00056-4
295252 Agelas dispar: 10.1021/NP970323H
63459 Chenopodium quinoa: 10.1021/JF0014462
42037 Silene italica: 10.1021/NP0205194
9606 Homo sapiens: -
384660 Cyathula officinalis Kuan: -
384659 Achyranthes bidentata Bl.: -
3498 Morus alba L.: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Susana Tavares Cotrim Ribeiro, Naiara Cássia Gancedo, Arildo José Braz de Oliveira, Regina Aparecida Correia Gonçalves. A comprehensive review of Pfaffia glomerata botany, ethnopharmacology, phytochemistry, biological activities, and biotechnology. Journal of ethnopharmacology. 2024 Jun; 328(?):118003. doi: 10.1016/j.jep.2024.118003. [PMID: 38484957]
Hai-Chao Wang, Ling Li, Jing-Hang Zhang, Zhi-Han Yao, Bao-Ping Pang. MicroRNA miR-7-5p targets MARK2 to control metamorphosis in Galeruca daurica. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2024 Jun; 272(?):110967. doi: 10.1016/j.cbpb.2024.110967. [PMID: 38521445]
Velislava Todorova, Stanislava Ivanova, Dzhevdet Chakarov, Krasimir Kraev, Kalin Ivanov. Ecdysterone and Turkesterone-Compounds with Prominent Potential in Sport and Healthy Nutrition. Nutrients. 2024 May; 16(9):. doi: 10.3390/nu16091382. [PMID: 38732627]
Yu-Xing Zhang, Qiao Tan, Lin Jin, Guo-Qing Li. Molecular characterization of the cytochrome P450 enzyme CYP18A1 in Henosepilachna vigintioctopunctata. Archives of insect biochemistry and physiology. 2024 Apr; 115(4):e22111. doi: 10.1002/arch.22111. [PMID: 38628055]
Haihui Xing, Guohua Chen, Faisal Raza, Hajra Zafar, Lei Xing, Qiaoyun Li, Ran Li, Shanshan Xu, Dan Chen. The Protective Effects of Ecdysterone on Cognitive Impairment through Regulating Akt/GSK-3β/Nrf2 Signaling Pathway and Oxidative Stress in Cognitive Mice Model and Aβ-Induced Cell Neurotoxicity. Frontiers in bioscience (Landmark edition). 2024 Mar; 29(3):109. doi: 10.31083/j.fbl2903109. [PMID: 38538266]
Yong Wang, Benjamin Buer, Cynthia L Goodman, David Kang, Tamra Reall, Susanne Dohn, Joseph Ringbauer, Yaofa Li, Sven Geibel, David Stanley. Indomethacin and 20-hydroxyecdysone influence protein expression in a Spodoptera frugiperda nervous system cell line. Archives of insect biochemistry and physiology. 2024 Feb; 115(2):e22089. doi: 10.1002/arch.22089. [PMID: 38409869]
Hugo Alarie, Nadia Côté, Luc Gaudreau, Magali Houde, Pedro A Segura. Are 20-hydroxyecdysone and related genes potential biomarkers of sublethal exposure to lipid-altering contaminants?. Environmental science and pollution research international. 2023 Dec; 30(60):126104-126115. doi: 10.1007/s11356-023-31087-2. [PMID: 38010540]
Kou Wang, Wen Liu, Xiao-Ping Wang. Dpp-mediated TGF-β signaling regulates vitellogenesis through 20-hydroxyecdysone signaling in the cabbage beetle, Colaphellus bowringi. Pesticide biochemistry and physiology. 2023 Dec; 197(?):105706. doi: 10.1016/j.pestbp.2023.105706. [PMID: 38072559]
Xinxin Gao, Jihong Zhang, Qilian Qin, Peipei Wu, Huan Zhang, Qian Meng. Metabolic changes during larval-pupal metamorphosis of Helicoverpa armigera. Insect science. 2023 Dec; 30(6):1663-1676. doi: 10.1111/1744-7917.13201. [PMID: 37200210]
Di Wen, Zhi Chen, Jiamin Wen, Qiangqiang Jia. Sterol Regulation of Development and 20-Hydroxyecdysone Biosynthetic and Signaling Genes in Drosophila melanogaster. Cells. 2023 Jun; 12(13):. doi: 10.3390/cells12131739. [PMID: 37443773]
Sheng-Yu Zhang, Han Gao, Ankarjan Askar, Xing-Peng Li, Guo-Cai Zhang, Tian-Zhong Jing, Hang Zou, Hao Guan, Yun-He Zhao, Chuan-Shan Zou. Steroid hormone 20-hydroxyecdysone disturbs fat body lipid metabolism and negatively regulates gluconeogenesis in Hyphantria cunea larvae. Insect science. 2023 Jun; 30(3):771-788. doi: 10.1111/1744-7917.13130. [PMID: 36342157]
Xue-Li Hou, Yu-Qi Gao, Jing-Hui Yang, Han-Wu Liu, Meng-Meng Bai, Zhen-Hai Wu, Chun-Huan Li, Jun-Mian Tian, Jin-Ming Gao. Phytoecdysteroids from Dianthus superbus L.: Structures and anti-neuroinflammatory evaluation. Phytochemistry. 2023 May; 212(?):113710. doi: 10.1016/j.phytochem.2023.113710. [PMID: 37178942]
Yongan Tan, Liubin Xiao, Jing Zhao, Jieyu Zhang, Sheraz Ahmad, Dejin Xu, Guangchun Xu, Linquan Ge. Adenosine Monophosphate-Activated Protein Kinase (AMPK) Phosphorylation Is Required for 20-Hydroxyecdysone Regulates Ecdysis in Apolygus lucorum. International journal of molecular sciences. 2023 May; 24(10):. doi: 10.3390/ijms24108587. [PMID: 37239932]
Tianran Li, Yinhao Ye, Peng Wu, Rengang Luo, Hongyu Zhang, Weiwei Zheng. Proteasome β3 subunit (PSMB3) controls female reproduction by promoting ecdysteroidogenesis during sexual maturation in Bactrocera dorsalis. Insect biochemistry and molecular biology. 2023 May; 157(?):103959. doi: 10.1016/j.ibmb.2023.103959. [PMID: 37172766]
Waly Dioh, Cendrine Tourette, Susanna Del Signore, Louiza Daudigny, Philippe Dupont, Christine Balducci, Pierre J Dilda, René Lafont, Stanislas Veillet. A Phase 1 study for safety and pharmacokinetics of BIO101 (20-hydroxyecdysone) in healthy young and older adults. Journal of cachexia, sarcopenia and muscle. 2023 Apr; ?(?):. doi: 10.1002/jcsm.13195. [PMID: 37057316]
Ruonan Zhang, Xue Chen, Yuan Wang, Xu Bai, Qiong Yang, Yangjin Zhong, Xiao-Qiang Yu, Fengliang Jin, Wanying Yang. BmMD-2A responds to 20-hydroxyecdysone and regulates Bombyx mori silkworm innate immunity in larva-to-pupa metamorphosis. Insect science. 2023 Apr; 30(2):411-424. doi: 10.1111/1744-7917.13097. [PMID: 35871306]
Siriporn Sripinyowanich, Sahanat Petchsri, Pumipat Tongyoo, Taek-Kyun Lee, Sukchan Lee, Won Kyong Cho. Comparative Transcriptomic Analysis of Genes in the 20-Hydroxyecdysone Biosynthesis in the Fern Microsorum scolopendria towards Challenges with Foliar Application of Chitosan. International journal of molecular sciences. 2023 Jan; 24(3):. doi: 10.3390/ijms24032397. [PMID: 36768717]
Jingnan Hu, Yu Feng, Baolin Li, Fengxia Wang, Qi Qian, Wei Tian, Liying Niu, Xinguo Wang. Identification of quality markers for Cyanotis arachnoidea and analysis of its physiological mechanism based on chemical pattern recognition, network pharmacology, and experimental validation. PeerJ. 2023; 11(?):e15948. doi: 10.7717/peerj.15948. [PMID: 37719108]
Weiwei Zheng, Fangyu Wu, Yinhao Ye, Tianran Li, Zhenyu Zhang, Hongyu Zhang. Small GTPase Rab40C is upregulated by 20-hydroxyecdysone and insulin pathways to regulate ovarian development and fecundity. Insect science. 2022 Dec; 29(6):1583-1600. doi: 10.1111/1744-7917.13026. [PMID: 35349758]
Feng Chen, Xiao-Qing Zhang, Jian-Jian Wu, Lin Jin, Guo-Qing Li. Requirement of Myoglianin for metamorphosis in the beetle Henosepilachna vigintioctopunctata. Insect molecular biology. 2022 12; 31(6):671-685. doi: 10.1111/imb.12795. [PMID: 35661293]
Blaise Cedric Kamdoum, Ingrid Simo, Steven Collins Njonte Wouamba, Brice Mariscal Tchatat Tali, Bathelemy Ngameni, Ghislain Wabo Fotso, Pantaléon Ambassa, Fekam Boyom Fabrice, Bruno Ndjakou Lenta, Norbert Sewald, Bonaventure Tchaleu Ngadjui. Chemical constituents of two Cameroonian medicinal plants: Sida rhombifolia L. and Sida acuta Burm. f. (Malvaceae) and their antiplasmodial activity. Natural product research. 2022 Oct; 36(20):5311-5318. doi: 10.1080/14786419.2021.1937156. [PMID: 34121522]
Jingjing Li, Letong Yin, Jingxiu Bi, David Stanley, Qili Feng, Qisheng Song. The TGF-β Receptor Gene Saxophone Influences Larval-Pupal-Adult Development in Tribolium castaneum. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27186017. [PMID: 36144752]
Qiang Zhang, Wei Dou, Clauvis Nji Tizi Taning, Shan-Shan Yu, Guo-Rui Yuan, Feng Shang, Guy Smagghe, Jin-Jun Wang. miR-309a is a regulator of ovarian development in the oriental fruit fly Bactrocera dorsalis. PLoS genetics. 2022 09; 18(9):e1010411. doi: 10.1371/journal.pgen.1010411. [PMID: 36112661]
Zhi-Xiong Zhou, Wei Dou, Chuan-Ren Li, Jin-Jun Wang. CYP314A1-dependent 20-hydroxyecdysone biosynthesis is involved in regulating the development of pupal diapause and energy metabolism in the Chinese citrus fruit fly, Bactrocera minax. Pest management science. 2022 Aug; 78(8):3384-3393. doi: 10.1002/ps.6966. [PMID: 35514223]
Ugiloy Yusupova, Durbek Usmanov, Aziz Azamatov, Nurmurod Ramazonov, Jumadilla Rejepov. Phytochemical constituents and biological activities of Dianthus helenae Vved., growing in Uzbekistan. Natural product research. 2022 Jul; 36(13):3480-3484. doi: 10.1080/14786419.2020.1862834. [PMID: 33342285]
Emmanuelle Claude, Rene Lafont, Robert S Plumb, Ian D Wilson. High performance Reversed-Phase Thin-Layer Chromatography-Desorption electrospray ionisation - time of flight high resolution mass spectrometric detection and imaging (HPTLC/DESI/ToFMS) of phytoecdysteroids. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2022 Jun; 1200(?):123265. doi: 10.1016/j.jchromb.2022.123265. [PMID: 35526348]
Jun-Li Du, Feng Chen, Jian-Jian Wu, Lin Jin, Guo-Qing Li. Smad on X is vital for larval-pupal transition in a herbivorous ladybird beetle. Journal of insect physiology. 2022 May; 139(?):104387. doi: 10.1016/j.jinsphys.2022.104387. [PMID: 35367434]
Artyom Y Baev, Oksana S Charishnikova, Feruzbek A Khasanov, Kamila S Nebesnaya, Albert R Makhmudov, Mannona T Rakhmedova, Zainab A Khushbaktova, Vladimir N Syrov, Yuliya V Levitskaya. Ecdysterone prevents negative effect of acute immobilization stress on energy metabolism of rat liver mitochondria. The Journal of steroid biochemistry and molecular biology. 2022 05; 219(?):106066. doi: 10.1016/j.jsbmb.2022.106066. [PMID: 35104603]
Li Wang, Shen Li, Hongda Cai, Xiaohu Liu, Tongtong Feng, Xiuhua Zhao. Preparation and characterisation of ecdysterone/hydroxypropyl-Β-cyclodextrin inclusion complex with enhanced oral and transdermal bioavailability. Journal of microencapsulation. 2022 Mar; 39(2):145-155. doi: 10.1080/02652048.2022.2056251. [PMID: 35311602]
Yanpeng Chang, Bo Zhang, Mengfang Du, Zichen Geng, Jizhen Wei, Ruobing Guan, Shiheng An, Wenli Zhao. The vital hormone 20-hydroxyecdysone controls ATP production by upregulating binding of trehalase 1 with ATP synthase subunit α in Helicoverpa armigera. The Journal of biological chemistry. 2022 02; 298(2):101565. doi: 10.1016/j.jbc.2022.101565. [PMID: 34999119]
Lang You, Zhiqian Li, Zhongjie Zhang, Bo Hu, Ye Yu, Fangying Yang, Anjiang Tan. Two dehydroecdysone reductases act as fat body-specific 20E catalyzers in Bombyx mori. Insect science. 2022 Feb; 29(1):100-110. doi: 10.1111/1744-7917.12928. [PMID: 34018323]
Chunyan Fang, Yaqun Xin, Tao Sun, Antónia Monteiro, Zhanfeng Ye, Fangyin Dai, Cheng Lu, Xiaoling Tong. The Hox gene Antennapedia is essential for wing development in insects. Development (Cambridge, England). 2022 01; 149(2):. doi: 10.1242/dev.199841. [PMID: 35088829]
Abdurakhim Toychiev, Fikrat Kerimov, Jannat Islamova, Mukambar Shaislamova, Murod Mirzakhmedov, Nikolay Davis, Vladimir Syrov, Svetlana Osipova. Antiprotozoal effect of steroid hormone 20-hydroxyecdysone in giardiosis patients. Annals of parasitology. 2022; 68(3):605-615. doi: 10.17420/ap6803.467. [PMID: 36617399]
Baoyu Fu, Rui Ma, Fangbing Liu, Xuenan Chen, Xiaoyu Teng, Pengdi Yang, Jianzeng Liu, Daqing Zhao, Liwei Sun. Ginsenosides improve reproductive capability of aged female Drosophila through mechanism dependent on ecdysteroid receptor (ECR) and steroid signaling pathway. Frontiers in endocrinology. 2022; 13(?):964069. doi: 10.3389/fendo.2022.964069. [PMID: 36017314]
Kui Hu, Baobao Fu, Chuchu Wang, Jianqi Liu, Yingying Tang, Wendan Zhang, Jun Zhu, Yao Li, Qinjian Pan, Fang Liu. The role of 20E biosynthesis relative gene Shadow in the reproduction of the predatory mirid bug, Cyrtorhinus lividipennis (Hemiptera: Miridae). Archives of insect biochemistry and physiology. 2022 Jan; 109(1):e21854. doi: 10.1002/arch.21854. [PMID: 34783381]
Yanghua Tang, Yafeng Mo, Dawei Xin, Zhenfei Xiong, Linru Zeng, Gan Luo, Yanguang Cao. Regulation of osteoblast autophagy based on PI3K/AKT/mTOR signaling pathway study on the effect of β-ecdysterone on fracture healing. Journal of orthopaedic surgery and research. 2021 Dec; 16(1):719. doi: 10.1186/s13018-021-02862-z. [PMID: 34924000]
Wei Wang, Ya Ma, Rui-Rui Yang, Xu Cheng, Hai-Jian Huang, Chuan-Xi Zhang, Yan-Yuan Bao. An MD-2-related lipid-recognition protein is required for insect reproduction and integument development. Open biology. 2021 12; 11(12):210170. doi: 10.1098/rsob.210170. [PMID: 34905699]
Li Yang, Thomas Friedemann, Jian Pan. Ecdysterone Attenuates the Development of Radiation-Induced Oral Mucositis in Rats at Early Stage. Radiation research. 2021 10; 196(4):366-374. doi: 10.1667/rade-21-00042.1. [PMID: 34237140]
Gui-Jie Wang, Wen-Wen Wang, Yu Liu, Lian-Qin Chai, Guo-Xiu Wang, Xu-Sheng Liu, Yu-Feng Wang, Jia-Lin Wang. Steroid hormone 20-hydroxyecdysone promotes CTL1-mediated cellular immunity in Helicoverpa armigera. Insect science. 2021 Oct; 28(5):1399-1413. doi: 10.1111/1744-7917.12851. [PMID: 32677271]
Safa Khelifi, Khadija Saad, Ariadni Vonaparti, Souhila Mahieddine, Sofia Salama, Amal Saleh, Maryam Al-Mohannadi, Hussain Al-Thaiban, Arjen Lommen, Peter Horvatovich, Alka Beotra, Wadha Abushareeda, Mohammed Al Maadheed, Costas Georgakopoulos. Ultra-fast retroactive processing by MetAlign of liquid chromatography/high-resolution full-scan Orbitrap mass spectrometry data in WADA Human Urine Sample Monitoring Program. Rapid communications in mass spectrometry : RCM. 2021 Sep; 35(17):e9141. doi: 10.1002/rcm.9141. [PMID: 34106497]
Christine Balducci, Laurence Dinan, Louis Guibout, Anne-Sophie Foucault, Christel Carbonne, Jean-Denis Durand, Cédric Caradeuc, Gildas Bertho, Jean-Pierre Girault, René Lafont. The complex metabolism of poststerone in male rats. The Journal of steroid biochemistry and molecular biology. 2021 09; 212(?):105897. doi: 10.1016/j.jsbmb.2021.105897. [PMID: 33862260]
L Dinan, C Balducci, L Guibout, A-S Foucault, A Bakrim, S Kumpun, J-P Girault, C Tourette, W Dioh, P J Dilda, S Veillet, R Lafont. Ecdysteroid metabolism in mammals: The fate of ingested 20-hydroxyecdysone in mice and rats. The Journal of steroid biochemistry and molecular biology. 2021 09; 212(?):105896. doi: 10.1016/j.jsbmb.2021.105896. [PMID: 33819630]
Peirong Li, Xinru Li, Wei Wang, Xiaoling Tan, Xiaoqi Wang, Xueqing Yang. Transcriptional identification of differentially expressed genes during the prepupal-pupal transition in the oriental armyworm, Mythimna separata (Walker) (Lepidoptera: Noctuidae). Bulletin of entomological research. 2021 Aug; 111(4):485-498. doi: 10.1017/s0007485321000171. [PMID: 33745467]
Wei-Nan Kang, Bing-Yao Wang, Kai-Yun Fu, Wen-Chao Guo, Lin Jin, Guo-Qing Li. The Leptinotarsa forkhead transcription factor O exerts a key function during larval-pupal-adult transition. Journal of insect physiology. 2021 07; 132(?):104266. doi: 10.1016/j.jinsphys.2021.104266. [PMID: 34126099]
Junzhu Han, Jianzhong Guan, Xunbing Zhu. β-Ecdysone attenuates cartilage damage in a mouse model of collagenase-induced osteoarthritis via mediating FOXO1/ADAMTS-4/5 signaling axis. Histology and histopathology. 2021 Jul; 36(7):785-794. doi: 10.14670/hh-18-341. [PMID: 33876419]
Souhail Kraiem, Maneera Y Al-Jaber, Hana Al-Mohammed, Afnan S Al-Menhali, Noora Al-Thani, Murad Helaleh, Waseem Samsam, Soufiane Touil, Alka Beotra, Costas Georgakopoulas, Sondes Bouabdallah, Vidya Mohamed-Ali, Mohammed Al Maadheed. Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)-SCID mice with humanized liver, human urine samples, and estimation of prevalence of its use in anti-doping samples. Drug testing and analysis. 2021 Jul; 13(7):1341-1353. doi: 10.1002/dta.3032. [PMID: 33759363]
P V P Nascimento, F Almeida-Oliveira, A Macedo-Silva, P Ausina, C Motinha, M Sola-Penna, D Majerowicz. Gene annotation of nuclear receptor superfamily genes in the kissing bug Rhodnius prolixus and the effects of 20-hydroxyecdysone on lipid metabolism. Insect molecular biology. 2021 06; 30(3):297-314. doi: 10.1111/imb.12696. [PMID: 33455040]
C-H Shen, Q-Y Xu, K-Y Fu, W-C Guo, L Jin, G-Q Li. Ecdysis triggering hormone is essential for larva-pupa-adult transformation in Leptinotarsa decemlineata. Insect molecular biology. 2021 06; 30(3):241-252. doi: 10.1111/imb.12691. [PMID: 33368728]
Magdalena J M Marschall, Robert Ringseis, Denise K Gessner, Sarah M Grundmann, Erika Most, Gaiping Wen, Garima Maheshwari, Holger Zorn, Klaus Eder. Effect of Ecdysterone on the Hepatic Transcriptome and Lipid Metabolism in Lean and Obese Zucker Rats. International journal of molecular sciences. 2021 May; 22(10):. doi: 10.3390/ijms22105241. [PMID: 34063487]
Mathilde Latil, Serge Camelo, Stanislas Veillet, René Lafont, Pierre J Dilda. Developing new drugs that activate the protective arm of the renin-angiotensin system as a potential treatment for respiratory failure in COVID-19 patients. Drug discovery today. 2021 05; 26(5):1311-1318. doi: 10.1016/j.drudis.2021.02.010. [PMID: 33609783]
Yu-Qin Di, Xiao-Lin Han, Xin-Le Kang, Di Wang, Cai-Hua Chen, Jin-Xing Wang, Xiao-Fan Zhao. Autophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis. Autophagy. 2021 05; 17(5):1170-1192. doi: 10.1080/15548627.2020.1752497. [PMID: 32324083]
Juan Zhu, Yan-Rong Chen, Tao Geng, Shun-Ming Tang, Qiao-Ling Zhao, Xing-Jia Shen. A 14-amino acids deletion in BmShadow results to non-moult on the 2nd instar in the bivoltine silkworm, Bombyx mori. Gene. 2021 Apr; 777(?):145450. doi: 10.1016/j.gene.2021.145450. [PMID: 33516793]
Hadjer Agoun, Nesrine Semiane, Aicha Mallek, Zineb Bellahreche, Soumia Hammadi, Maha Madjerab, Mohamed Abdlalli, Ali Khalkhal, Yasmina Dahmani. High-carbohydrate diet-induced metabolic disorders in Gerbillus tarabuli (a new model of non-alcoholic fatty-liver disease). Protective effects of 20-hydroxyecdysone. Archives of physiology and biochemistry. 2021 Apr; 127(2):127-135. doi: 10.1080/13813455.2019.1621350. [PMID: 31190566]
Caihong Ji, Nan Zhang, Heng Jiang, Xiangkun Meng, Huichen Ge, Xuemei Yang, Xin Xu, Kun Qian, Yoonseong Park, Yang Zheng, Jianjun Wang. 20-hydroxyecdysone regulates expression of methioninesulfoxide reductases through transcription factor FOXO in the red flour beetle, Tribolium castaneum. Insect biochemistry and molecular biology. 2021 04; 131(?):103546. doi: 10.1016/j.ibmb.2021.103546. [PMID: 33548484]
Yong-An Tan, Xu-Dong Zhao, Hou-Jun Sun, Jing Zhao, Liu-Bin Xiao, De-Jun Hao, Yi-Pin Jiang. Phospholipase C gamma (PLCγ) regulates soluble trehalase in the 20E-induced fecundity of Apolygus lucorum. Insect science. 2021 Apr; 28(2):430-444. doi: 10.1111/1744-7917.12772. [PMID: 32108427]
Rodrigo Rodrigues Franco, Letícia de Almeida Takata, Kristhiano Chagas, Allisson Benatti Justino, André Lopes Saraiva, Luiz Ricardo Goulart, Veridiana de Melo Rodrigues Ávila, Wagner Campos Otoni, Foued Salmen Espindola, Cássia Regina da Silva. A 20-hydroxyecdysone-enriched fraction from Pfaffia glomerata (Spreng.) pedersen roots alleviates stress, anxiety, and depression in mice. Journal of ethnopharmacology. 2021 Mar; 267(?):113599. doi: 10.1016/j.jep.2020.113599. [PMID: 33220360]
Wanna Zhang, Long Ma, Xiangya Liu, Yingchuan Peng, Gemei Liang, Haijun Xiao. Dissecting the roles of FTZ-F1 in larval molting and pupation, and the sublethal effects of methoxyfenozide on Helicoverpa armigera. Pest management science. 2021 Mar; 77(3):1328-1338. doi: 10.1002/ps.6146. [PMID: 33078511]
Zidan Zhu, Chunmei Tong, Binbin Qiu, Hongguang Yang, Jiahui Xu, Sichun Zheng, Qisheng Song, Qili Feng, Huimin Deng. 20E-mediated regulation of BmKr-h1 by BmKRP promotes oocyte maturation. BMC biology. 2021 02; 19(1):39. doi: 10.1186/s12915-021-00952-2. [PMID: 33632227]
Z-M Yang, N Yu, S-J Wang, S K Korai, Z-W Liu. Characterization of ecdysteroid biosynthesis in the pond wolf spider, Pardosa pseudoannulata. Insect molecular biology. 2021 02; 30(1):71-80. doi: 10.1111/imb.12678. [PMID: 33131130]
Shuang Guo, Zhong Tian, Qing-Wen Wu, Kirst King-Jones, Wen Liu, Fen Zhu, Xiao-Ping Wang. Steroid hormone ecdysone deficiency stimulates preparation for photoperiodic reproductive diapause. PLoS genetics. 2021 02; 17(2):e1009352. doi: 10.1371/journal.pgen.1009352. [PMID: 33529191]
W Dioh, M Chabane, C Tourette, A Azbekyan, C Morelot-Panzini, L A Hajjar, M Lins, G B Nair, T Whitehouse, J Mariani, M Latil, S Camelo, R Lafont, P J Dilda, S Veillet, S Agus. Testing the efficacy and safety of BIO101, for the prevention of respiratory deterioration, in patients with COVID-19 pneumonia (COVA study): a structured summary of a study protocol for a randomised controlled trial. Trials. 2021 Jan; 22(1):42. doi: 10.1186/s13063-020-04998-5. [PMID: 33430924]
Tsai-Chi Shang Kuan, Roger K Prichard. Developmental regulation of Dirofilaria immitis microfilariae and evaluation of ecdysone signaling pathway transcript level using droplet digital PCR. Parasites & vectors. 2020 Dec; 13(1):614. doi: 10.1186/s13071-020-04480-w. [PMID: 33298156]
Nan Zhang, Heng Jiang, Xiangkun Meng, Kun Qian, Yaping Liu, Qisheng Song, David Stanley, Jincai Wu, Yoonseong Park, Jianjun Wang. Broad-complex transcription factor mediates opposing hormonal regulation of two phylogenetically distant arginine kinase genes in Tribolium castaneum. Communications biology. 2020 10; 3(1):631. doi: 10.1038/s42003-020-01354-w. [PMID: 33127981]
Sylwia Bajkacz, Kornelia Rusin, Anna Wolny, Jakub Adamek, Karol Erfurt, Anna Chrobok. Highly Efficient Extraction Procedures Based on Natural Deep Eutectic Solvents or Ionic Liquids for Determination of 20-Hydroxyecdysone in Spinach. Molecules (Basel, Switzerland). 2020 Oct; 25(20):. doi: 10.3390/molecules25204736. [PMID: 33076445]
Shu Huang, Qilin Yi, Xingye Lian, Siqi Xu, Chuanyan Yang, Jiejie Sun, Lingling Wang, Linsheng Song. The involvement of ecdysone and ecdysone receptor in regulating the expression of antimicrobial peptides in Chinese mitten crab, Eriocheir sinensis. Developmental and comparative immunology. 2020 10; 111(?):103757. doi: 10.1016/j.dci.2020.103757. [PMID: 32485180]
Pengfei Han, Qitian Gong, Jiqiao Fan, Min Zhang, Mureed Abbas, Wenya Zhu, Sufang Deng, Shuping Xing, Jianzhen Zhang. 20-Hydroxyecdysone regulates the prophenoloxidase cascade to immunize Metarhizium anisopliae in Locusta migratoria. Pest management science. 2020 Sep; 76(9):3149-3158. doi: 10.1002/ps.5869. [PMID: 32310328]
Chen-Hui Shen, Qing-Yu Xu, Li-Li Mu, Kai-Yun Fu, Wen-Chao Guo, Guo-Qing Li. Involvement of Leptinotarsa hormone receptor 38 in the larval-pupal transition. Gene. 2020 Aug; 751(?):144779. doi: 10.1016/j.gene.2020.144779. [PMID: 32428697]
Qing-Yu Xu, Pan Deng, Qiong Zhang, Ang Li, Kai-Yun Fu, Wen-Chao Guo, Guo-Qing Li. Ecdysone receptor isoforms play distinct roles in larval-pupal-adult transition in Leptinotarsa decemlineata. Insect science. 2020 Jun; 27(3):487-499. doi: 10.1111/1744-7917.12662. [PMID: 30688001]
Jariya Buniam, Natsasi Chukijrungroat, Yupaporn Rattanavichit, Juthamard Surapongchai, Jittima Weerachayaphorn, Tepmanas Bupha-Intr, Vitoon Saengsirisuwan. 20-Hydroxyecdysone ameliorates metabolic and cardiovascular dysfunction in high-fat-high-fructose-fed ovariectomized rats. BMC complementary medicine and therapies. 2020 May; 20(1):140. doi: 10.1186/s12906-020-02936-1. [PMID: 32375750]
Gabriella Ambrosio, Jan Felix Joseph, Bernhard Wuest, Monica Mazzarino, Xavier de la Torre, Patrick Diel, Francesco Botrè, Maria Kristina Parr. Detection and quantitation of ecdysterone in human serum by liquid chromatography coupled to tandem mass spectrometry. Steroids. 2020 05; 157(?):108603. doi: 10.1016/j.steroids.2020.108603. [PMID: 32068076]
Jiasheng Song, Shutang Zhou. Post-transcriptional regulation of insect metamorphosis and oogenesis. Cellular and molecular life sciences : CMLS. 2020 May; 77(10):1893-1909. doi: 10.1007/s00018-019-03361-5. [PMID: 31724082]
Dongwei Yuan, Shun Zhou, Suning Liu, Kang Li, Haigang Zhao, Shihui Long, Hanhan Liu, Yongfang Xie, Yunlin Su, Fengwei Yu, Sheng Li. The AMPK-PP2A axis in insect fat body is activated by 20-hydroxyecdysone to antagonize insulin/IGF signaling and restrict growth rate. Proceedings of the National Academy of Sciences of the United States of America. 2020 04; 117(17):9292-9301. doi: 10.1073/pnas.2000963117. [PMID: 32277029]
Rebekah A Reynolds, Hyeogsun Kwon, Ryan C Smith. 20-Hydroxyecdysone Primes Innate Immune Responses That Limit Bacterial and Malarial Parasite Survival in Anopheles gambiae. mSphere. 2020 04; 5(2):. doi: 10.1128/msphere.00983-19. [PMID: 32295874]
Tatiane Dulcineia Silva, Diego Silva Batista, Evandro Alexandre Fortini, Kamila Motta de Castro, Sérgio Heitor Sousa Felipe, Amanda Mendes Fernandes, Raysa Mayara de Jesus Sousa, Kristhiano Chagas, José Victor Siqueira da Silva, Ludmila Nayara de Freitas Correia, Letícia Monteiro Farias, João Paulo Viana Leite, Diego Ismael Rocha, Wagner Campos Otoni. Blue and red light affects morphogenesis and 20-hydroxyecdisone content of in vitro Pfaffia glomerata accessions. Journal of photochemistry and photobiology. B, Biology. 2020 Jan; 203(?):111761. doi: 10.1016/j.jphotobiol.2019.111761. [PMID: 31896050]
Jia Wang, Li-Lin Ran, Ying Li, Ying-Hong Liu. Comparative proteomics provides insights into diapause program of Bactrocera minax (Diptera: Tephritidae). PloS one. 2020; 15(12):e0244493. doi: 10.1371/journal.pone.0244493. [PMID: 33382763]
Pengfei Han, Jiao Han, Min Zhang, Jiqiao Fan, Qitian Gong, Enbo Ma, Jianzhen Zhang. 20-Hydroxyecdysone enhances Immulectin-1 mediated immune response against entomogenous fungus in Locusta migratoria. Pest management science. 2020 Jan; 76(1):304-313. doi: 10.1002/ps.5515. [PMID: 31207079]
Jia Zeng, Xianchao Shang, Peng Zhang, Hongwei Wang, Yanlong Gu, Jia-Neng Tan. Combined Use of Deep Eutectic Solvents, Macroporous Resins, and Preparative Liquid Chromatography for the Isolation and Purification of Flavonoids and 20-Hydroxyecdysone from Chenopodium quinoa Willd. Biomolecules. 2019 11; 9(12):. doi: 10.3390/biom9120776. [PMID: 31775374]
Cai-Hua Chen, Yu-Qin Di, Qin-Yong Shen, Jin-Xing Wang, Xiao-Fan Zhao. The steroid hormone 20-hydroxyecdysone induces phosphorylation and aggregation of stromal interacting molecule 1 for store-operated calcium entry. The Journal of biological chemistry. 2019 10; 294(41):14922-14936. doi: 10.1074/jbc.ra119.008484. [PMID: 31413111]
Qing-Yu Xu, Pan Deng, Li-Li Mu, Kai-Yun Fu, Wen-Chao Guo, Guo-Qing Li. Silencing Taiman impairs larval development in Leptinotarsa decemlineata. Pesticide biochemistry and physiology. 2019 Oct; 160(?):30-39. doi: 10.1016/j.pestbp.2019.06.013. [PMID: 31519255]
Temitayo O Ajayi, Radhakrishnan Srivedavyasasri, Emmanuel E Nyong, Micheal A Odeniyi, Jones O Moody, Samir A Ross. Two new phytoecdysteroids from Sphenocentrum jollyanum Pierre root. Steroids. 2019 10; 150(?):108456. doi: 10.1016/j.steroids.2019.108456. [PMID: 31326452]
Q-Y Xu, Q-W Meng, P Deng, K-Y Fu, W-C Guo, G-Q Li. Impairment of pupation by RNA interference-aided knockdown of Broad-Complex gene in Leptinotarsa decemlineata (Say). Bulletin of entomological research. 2019 Oct; 109(5):659-668. doi: 10.1017/s0007485318001050. [PMID: 30704539]
Q-Y Xu, P Deng, A Li, Q Zhang, L-L Mu, K-Y Fu, W-C Guo, G-Q Li. Functional characterization of ultraspiracle in Leptinotarsa decemlineata using RNA interference assay. Insect molecular biology. 2019 10; 28(5):676-688. doi: 10.1111/imb.12580. [PMID: 30834617]
Ayoub Ajaha, Noureddin Bouayad, Ahmed Aarab, Kacem Rharrabe. Effect of 20-Hydroxyecdysone, a Phytoecdysteroid, on Development, Digestive, and Detoxification Enzyme Activities of Tribolium castaneum (Coleoptera: Tenebrionidae). Journal of insect science (Online). 2019 Sep; 19(5):. doi: 10.1093/jisesa/iez097. [PMID: 31639190]
Niramaya S Muchate, Nilima S Rajurkar, Penna Suprasanna, Tukaram D Nikam. NaCl induced salt adaptive changes and enhanced accumulation of 20-hydroxyecdysone in the in vitro shoot cultures of Spinacia oleracea (L.). Scientific reports. 2019 08; 9(1):12522. doi: 10.1038/s41598-019-48737-6. [PMID: 31467324]
Li-Wei Lin, Fan-Hsuan Tsai, Wan-Cheng Lan, Yih-Dih Cheng, Sheng-Chi Lee, Chi-Rei Wu. Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats. Molecular neurobiology. 2019 Aug; 56(8):5671-5688. doi: 10.1007/s12035-018-1436-7. [PMID: 30666561]
Md Abdullah Al Baki, Dae-Weon Lee, Jin Kyo Jung, Yonggyun Kim. Insulin signaling mediates previtellogenic development and enhances juvenile hormone-mediated vitellogenesis in a lepidopteran insect, Maruca vitrata. BMC developmental biology. 2019 07; 19(1):14. doi: 10.1186/s12861-019-0194-8. [PMID: 31277577]
Eduard Isenmann, Gabriella Ambrosio, Jan Felix Joseph, Monica Mazzarino, Xavier de la Torre, Philipp Zimmer, Rymantas Kazlauskas, Catrin Goebel, Francesco Botrè, Patrick Diel, Maria Kristina Parr. Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans. Archives of toxicology. 2019 07; 93(7):1807-1816. doi: 10.1007/s00204-019-02490-x. [PMID: 31123801]
Sérgio Heitor Sousa Felipe, Diego Silva Batista, Camilo Elber Vital, Kristhiano Chagas, Priscila Oliveira Silva, Tatiane Dulcineia Silva, Evandro Alexandre Fortini, Ludmila Nayara de Freitas Correia, Rodrigo Teixeira Ávila, Joseila Maldaner, Reginaldo Alves Festucci-Buselli, Fábio Murilo DaMatta, Wagner Campos Otoni. Salinity-induced modifications on growth, physiology and 20-hydroxyecdysone levels in Brazilian-ginseng [Pfaffia glomerata (Spreng.) Pedersen]. Plant physiology and biochemistry : PPB. 2019 Jul; 140(?):43-54. doi: 10.1016/j.plaphy.2019.05.002. [PMID: 31078783]
X Liu, S Zhang, Z J Shen, Y Liu, Z Li, X Liu. Vrille is required for larval moulting and metamorphosis of Helicoverpa armigera (Lepidoptera: Noctuidae). Insect molecular biology. 2019 06; 28(3):355-371. doi: 10.1111/imb.12557. [PMID: 30485565]
Xinhai Ye, Le Xu, Xiang Li, Kang He, Hongxia Hua, Zhenghong Cao, Jiadan Xu, Wanyi Ye, Jiao Zhang, Zhuting Yuan, Fei Li. miR-34 modulates wing polyphenism in planthopper. PLoS genetics. 2019 06; 15(6):e1008235. doi: 10.1371/journal.pgen.1008235. [PMID: 31242182]
Dong Wei, Ying-Xin Zhang, Yu-Wei Liu, Wei-Jun Li, Zhi-Xian Chen, Guy Smagghe, Jin-Jun Wang. Gene expression profiling of ovary identified eggshell proteins regulated by 20-hydroxyecdysone in Bactrocera dorsalis. Comparative biochemistry and physiology. Part D, Genomics & proteomics. 2019 06; 30(?):206-216. doi: 10.1016/j.cbd.2019.03.006. [PMID: 30909163]
Diego Silva Batista, Andréa Dias Koehler, Elisson Romanel, Vinícius Cairus de Souza, Tatiane Dulcineia Silva, Maíra Carolina Almeida, Talles Elisson F Maciel, Perácio Rafael Bueno Ferreira, Sérgio Heitor Sousa Felipe, Cleber Witt Saldanha, Joseila Maldaner, Leonardo Lucas Carnevalli Dias, Reginaldo Alves Festucci-Buselli, Wagner Campos Otoni. De novo assembly and transcriptome of Pfaffia glomerata uncovers the role of photoautotrophy and the P450 family genes in 20-hydroxyecdysone production. Protoplasma. 2019 May; 256(3):601-614. doi: 10.1007/s00709-018-1322-1. [PMID: 30357479]
Feng Wen, Jun Yu, Cheng-Jian He, Zhi-Wen Zhang, Ao-Fei Yang. β‑ecdysterone protects against apoptosis by promoting autophagy in nucleus pulposus cells and ameliorates disc degeneration. Molecular medicine reports. 2019 03; 19(3):2440-2448. doi: 10.3892/mmr.2019.9861. [PMID: 30664184]
Renata Vardanega, Aline F V Muzio, Eric Keven Silva, Ana Silvia Prata, M Angela A Meireles. Obtaining functional powder tea from Brazilian ginseng roots: Effects of freeze and spray drying processes on chemical and nutritional quality, morphological and redispersion properties. Food research international (Ottawa, Ont.). 2019 02; 116(?):932-941. doi: 10.1016/j.foodres.2018.09.030. [PMID: 30717026]
J-J Wu, Z-C Chen, Y-W Wang, K-Y Fu, W-C Guo, G-Q Li. Silencing chitin deacetylase 2 impairs larval-pupal and pupal-adult molts in Leptinotarsa decemlineata. Insect molecular biology. 2019 02; 28(1):52-64. doi: 10.1111/imb.12524. [PMID: 30058750]
Hongwei Wang, Jianeng Tan, Xianchao Shang, Xuan Zheng, Xinmin Liu, Jing Wang, Xiaodong Hou, Yongmei Du. Porous organic cage incorporated monoliths for solid-phase extraction coupled with liquid chromatography-mass spectrometry for identification of ecdysteroids from Chenopodium quinoa Willd. Journal of chromatography. A. 2019 Jan; 1583(?):55-62. doi: 10.1016/j.chroma.2018.11.019. [PMID: 30477713]
Qing-Wei Meng, Qing-Yu Xu, Tao-Tao Zhu, Lin Jin, Kai-Yun Fu, Wen-Chao Guo, Guo-Qing Li. Hormonal signaling cascades required for phototaxis switch in wandering Leptinotarsa decemlineata larvae. PLoS genetics. 2019 01; 15(1):e1007423. doi: 10.1371/journal.pgen.1007423. [PMID: 30615614]
Pan Deng, Qing-Yu Xu, Kai-Yun Fu, Wen-Chao Guo, Guo-Qing Li. RNA interference against the putative insulin receptor substrate gene chico affects metamorphosis in Leptinotarsa decemlineata. Insect biochemistry and molecular biology. 2018 12; 103(?):1-11. doi: 10.1016/j.ibmb.2018.10.001. [PMID: 30296480]
N S Muchate, N S Rajurkar, P Suprasanna, T D Nikam. Evaluation of Spinacia oleracea (L.) for phytodesalination and augmented production of bioactive metabolite, 20-hydroxyecdysone. International journal of phytoremediation. 2018 Aug; 20(10):981-994. doi: 10.1080/15226514.2018.1452184. [PMID: 30095306]