Crustecdysone (BioDeep_00000407045)

natural product PANOMIX_OTCML-2023

代谢物信息卡片

20-Hydroxyecdysone

化学式: C27H44O7 (480.3087)
中文名称: 蜕皮激素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(O)CC[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C
InChI: InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
SubCategory_DNP: : The sterols, Cholestanes
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1]. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2]. Crustecdysone is an active metabolite of Ecdysone (HY-N0179)[3].
Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP[1]. Crustecdysone exhibits regulatory or protective roles in the cardiovascular system[2]. Crustecdysone is an active metabolite of Ecdysone (HY-N0179)[3].

同义名列表

4 个代谢物同义名

Hydroxyecdysone; Crustecdysone; 20-Hydroxyecdysone; 20-Hydroxyecdysone

数据库引用编号

38 个数据库交叉引用编号

分类词条

类固醇

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

150 个相关的物种来源信息

240005 - Achyranthes aspera: 10.1007/PL00010306
384659 - Achyranthes bidentata Bl.: -
165205 - Afrocarpus gracilior: 10.1016/J.PHYTOL.2012.02.005
295252 - Agelas dispar:
1736745 - Ajuga chamaecistus: 10.1016/S0021-9673(01)88168-1
49984 - Ajuga chamaepitys: 10.1016/S0031-9422(00)84101-1
167911 - Ajuga decumbens: 10.1248/CPB.17.340
2026104 - Ajuga iva: 10.1016/S0031-9422(00)97527-7
984302 - Ajuga nipponensis: 10.1248/CPB.17.340
38596 - Ajuga reptans:
41472 - Amberboa moschata: 10.1016/S0305-1978(97)00018-5
470566 - Anemone alpina: 10.1016/S0305-1978(97)00042-2
387932 - Anemone montana: 10.1016/S0305-1978(97)00042-2
174168 - Anemone occidentalis: 10.1016/S0305-1978(97)00042-2
445234 - Anemone pulsatilla: 10.1016/S0305-1978(97)00042-2
7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
72517 - Arilus cristatus: 10.1007/BF01946477
6252 - Ascaris lumbricoides: 10.1007/BF01923635
100515 - Asparagus filicinus: 10.1016/S0031-9422(99)00051-5
65704 - Athyrium yokoscense: 10.1016/0031-9422(95)00688-5
3553 - Atriplex nummularia: 10.1016/S0367-326X(99)00159-8
376799 - Atriplex portulacoides: 10.1016/J.BMCL.2015.03.028
464020 - Axyris amaranthoides: 10.1016/S0031-9422(98)00446-4
6526 - Biomphalaria glabrata: 10.1007/BF01959769
49702 - Blandfordia punicea: 10.1021/NP960377B
122298 - Blitum bonus-henricus: 10.1016/0031-9422(82)80057-5
7091 - Bombyx mori:
120713 - Brainea insignis: 10.1016/J.PHYTOCHEM.2010.03.002
41536 - Centaurea melitensis:
80839 - Charybdis japonica: 10.1073/PNAS.86.17.6826
46091 - Chenopodiastrum murale: 10.1002/(SICI)1520-6327(1999)41:1<18::AID-ARCH4>3.0.CO;2-T
3559 - Chenopodium album:
882375 - Chenopodium pallidicaule: 10.1016/0305-1978(96)00019-1
63459 - Chenopodium quinoa:
79782 - Cimex lectularius: 10.1007/BF01946477
6535 - Cornu aspersum: 10.1007/BF01959769
1503182 - Cyanotis arachnoidea: 10.1080/10286020290019631
384660 - Cyathula officinalis Kuan: -
84614 - Cyrtomium falcatum: 10.1248/CPB.17.340
4164 - Digitalis purpurea: 10.1007/S10600-010-9551-3
152357 - Diploclisia glaucescens:
191328 - Dysdercus cingulatus: 10.1007/BF01946477
527504 - Fibraurea chloroleuca: 10.1002/PTR.2650070406
461588 - Fibraurea tinctoria: 10.1002/PTR.2650070406
46114 - Froelichia floridana:
59080 - Gagea serotina: 10.1016/S0305-1978(01)00021-7
2528985 - Gomphrena affinis: 10.1016/S0305-1978(97)00106-3
2528987 - Gomphrena canescens: 10.1016/S0305-1978(97)00106-3
2528988 - Gomphrena cunninghamii: 10.1016/S0305-1978(97)00106-3
221775 - Gomphrena globosa: 10.1016/S0305-1978(97)00106-3
240061 - Gomphrena haageana: 10.1016/S0305-1978(97)00106-3
221778 - Gomphrena serrata: 10.1016/S0305-1978(97)00106-3
2873767 - Haematocarpus subpeltatus: 10.1002/PTR.2650070406
171888 - Helleborus cyclophyllus: 10.1016/J.JEP.2020.112954
171897 - Helleborus odorus:
171898 - Helleborus orientalis: 10.1016/J.PHYTOCHEM.2007.11.007
171899 - Helleborus purpurascens:
171901 - Helleborus torquatus: 10.1016/S0031-9422(01)00070-X
171903 - Helleborus viridis: 10.3109/13880209009082817
283497 - Iotrochota birotulata: 10.1016/S0039-128X(99)00096-3
82527 - Ipheion uniflorum: 10.1248/CPB.42.1116
305367 - Klasea centauroides: 10.1007/BF00574363
305371 - Klasea erucifolia:
354313 - Klasea marginata: 10.1007/BF00574363
354317 - Klasea procumbens: 10.1007/BF00574363
305379 - Klasea quinquefolia: 10.1007/BF00574363
354320 - Klasea sogdiana: 10.1007/BF00574363
224738 - Lepidothamnus intermedius: 10.1071/CH9721935
42439 - Limnanthes alba: 10.1515/ZNC-2001-11-1214
28973 - Limnanthes douglasii: 10.1016/S0031-9422(96)00591-2
13824 - Lygodium japonicum: 10.1007/S11418-009-0376-Y
13123 - Lymantria dispar: 10.1002/ARCH.940010404
6523 - Lymnaea stagnalis: 10.1007/BF01959769
7130 - Manduca sexta:
3498 - Morus alba L.: -
85310 - Nezara viridula: 10.1007/BF01946477
144308 - Nierembergia hippomanica: 10.1016/0031-9422(95)00731-8
274375 - Nierembergia linariifolia: 10.1016/0031-9422(95)00731-8
7536 - Oncopeltus fasciatus: 10.1007/BF01946477
292312 - Ourisia caespitosa: 10.1016/S0305-1978(96)00083-X
292327 - Ourisia macrocarpa: 10.1016/S0305-1978(96)00083-X
292330 - Ourisia macrophylla: 10.1016/S0305-1978(96)00083-X
86596 - Palythoa: 10.1007/BF00598556
44685 - Panax japonicus: 10.1002/HLCA.201100085
44924 - Parazoanthus:
49666 - Paris polyphylla:
221254 - Paris polyphylla var. chinensis:
231488 - Paris quadrifolia: 10.1007/BF00574363
2708930 - Penianthus zenkeri: 10.1016/0031-9422(91)85047-4
265172 - Penstemon venustus: 10.1016/0031-9422(94)00948-S
221785 - Pfaffia glomerata:
451963 - Pfaffia iresinoides:
41506 - Plectocephalus americanus:
90697 - Plenasium banksiifolium: 10.1055/S-0028-1097493
29025 - Podisus maculiventris: 10.1007/BF01946477
38391 - Polypodium fauriei: 10.1248/CPB.17.340
872808 - Polypodium virginianum:
58048 - Polypodium vulgare:
1729754 - Poranopsis discifera: 10.1016/0039-128X(76)90006-4
261975 - Pycnogonum litorale: 10.1515/ZNC-1994-5-615
362630 - Rhaponticum carthamoides:
362636 - Rhaponticum integrifolium:
362639 - Rhaponticum lyratum: 10.1007/BF00574363
362646 - Rhaponticum uniflorum:
13249 - Rhodnius prolixus: 10.1007/BF01946477
254022 - Sagina japonica: 10.1007/S10600-010-9729-8
7010 - Schistocerca gregaria: 10.1039/C39810000418
65004 - Serratula tinctoria:
108380 - Sida spinosa: 10.1016/S0031-9422(03)00021-9
1930050 - Sida szechuensis: 10.14233/AJCHEM.2014.15427
1137874 - Silene banksia: 10.1007/BF00598381
1937749 - Silene brahuica:
39855 - Silene chalcedonica:
42037 - Silene italica: 10.1021/NP0205194
37657 - Silene latifolia: 10.1007/BF00574363
39891 - Silene linicola:
39894 - Silene nemoralis: 10.1021/NP0205194
42038 - Silene nutans:
42039 - Silene otites:
2039599 - Silene spergulifolia: 10.1007/BF02254804
1309628 - Silene supina: 10.1007/BF02254804
39917 - Silene tatarica:
663359 - Silene turkestanica:
335148 - Silene viridiflora:
2082040 - Silene wallichiana:
1850527 - Silene wilfordii: 10.1007/BF00636589
3562 - Spinacia oleracea:
167472 - Stachyurus himalaicus: 10.3390/12030536
85277 - Stachyurus praecox: 10.1248/CPB.17.340
72122 - Tapinella atrotomentosa:
80604 - Tapinella panuoides: 10.1016/S0031-9422(98)00448-8
46220 - Taxus brevifolia: 10.1016/0031-9422(95)00672-9
99806 - Taxus cuspidata:
285590 - Tinospora cordifolia:
100602 - Trichobilharzia ocellata: 10.1016/0166-6851(91)90139-W
49675 - Trillium camschatcense: 10.1248/CPB.55.551
50545 - Trillium erectum: 10.1016/J.PHYTOCHEM.2008.10.019
82499 - Trillium smallii: 10.1248/CPB.17.340
82502 - Trillium tschonoskii: 10.1248/CPB.17.340
87477 - Trisetum flavescens: 10.1016/S0305-1978(97)00087-2
413480 - Vitex canescens:
2364071 - Vitex cymosa: 10.1016/S0367-326X(00)00304-X
413482 - Vitex glabrata: 10.1021/NP50044A041
1899206 - Vitex madiensis:
1365883 - Vitex megapotamica: 10.1002/ARDP.19723051007
548852 - Vitex pinnata: 10.1016/S0031-9422(00)94985-9
2709034 - Vitex thyrsiflora: 10.1016/S0021-9673(01)90442-X
548845 - Vitex tripinnata: 10.1016/S0031-9422(98)00411-7
86683 - Woodwardia orientalis: 10.1248/CPB.41.1803
105401 - Zoanthus: 10.1021/NP010645S

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表
Cytoplasm	11	AKT1, BCL2, BGLAP, CASP3, CAT, DDC, HSPB1, MTOR, PIK3CA, PTEN, RUNX2
Peripheral membrane protein	3	ACHE, CYP1B1, MTOR
Endosome membrane	1	INSR
Endoplasmic reticulum membrane	4	BCL2, CYP1B1, HSP90B1, MTOR
Nucleus	11	ACHE, AKT1, BCL2, CASP3, HSP90B1, HSPB1, MTOR, PLCZ1, PTEN, RUNX2, USP1
cytosol	13	AKT1, BCL2, CASP3, CAT, DDC, HSP90B1, HSPB1, MTOR, PIK3CA, PLCZ1, PTEN, RUNX2, USP1
dendrite	2	BGLAP, MTOR
phagocytic vesicle	1	MTOR
nucleoplasm	7	AKT1, CASP3, MTOR, PLCZ1, PTEN, RUNX2, USP1
Cell membrane	4	ACHE, AKT1, INSR, TREH
Cytoplasmic side	1	MTOR
lamellipodium	2	AKT1, PIK3CA
Golgi apparatus membrane	1	MTOR
Synapse	1	ACHE
cell cortex	1	AKT1
cell surface	1	ACHE
glutamatergic synapse	2	AKT1, CASP3
Golgi apparatus	1	ACHE
Golgi membrane	2	INS, MTOR
lysosomal membrane	1	MTOR
neuromuscular junction	1	ACHE
neuronal cell body	1	CASP3
postsynapse	1	AKT1
smooth endoplasmic reticulum	1	HSP90B1
Lysosome	2	INSR, MTOR
plasma membrane	6	ACHE, AKT1, INSR, PIK3CA, PTEN, TREH
Membrane	9	ACHE, AKT1, BCL2, CAT, CYP1B1, HSP90B1, INSR, MTOR, TREH
apical plasma membrane	1	PTEN
axon	1	INSR
caveola	1	INSR
extracellular exosome	6	CAT, DDC, HSP90B1, HSPB1, INSR, TREH
Lysosome membrane	1	MTOR
endoplasmic reticulum	2	BCL2, HSP90B1
extracellular space	5	ACHE, BGLAP, HSPB1, IL6, INS
perinuclear region of cytoplasm	4	ACHE, HSP90B1, PIK3CA, PLCZ1
intercalated disc	1	PIK3CA
mitochondrion	3	BCL2, CAT, CYP1B1
protein-containing complex	4	AKT1, BCL2, CAT, HSP90B1
intracellular membrane-bounded organelle	2	CAT, CYP1B1
Microsome membrane	2	CYP1B1, MTOR
postsynaptic density	2	CASP3, PTEN
pronucleus	1	PLCZ1
TORC1 complex	1	MTOR
TORC2 complex	1	MTOR
Single-pass type I membrane protein	1	INSR
Secreted	4	ACHE, BGLAP, IL6, INS
extracellular region	7	ACHE, BGLAP, CAT, HSP90B1, IL6, INS, PTEN
cytoplasmic side of plasma membrane	1	PTEN
Mitochondrion outer membrane	2	BCL2, MTOR
Single-pass membrane protein	1	BCL2
mitochondrial outer membrane	2	BCL2, MTOR
neuronal cell body membrane	1	INSR
mitochondrial matrix	1	CAT
Extracellular side	1	ACHE
transcription regulator complex	1	RUNX2
Nucleus membrane	1	BCL2
Bcl-2 family protein complex	1	BCL2
nuclear membrane	1	BCL2
external side of plasma membrane	1	INSR
dendritic spine	1	PTEN
perikaryon	1	BGLAP
Z disc	1	HSPB1
microtubule cytoskeleton	1	AKT1
nucleolus	1	PLCZ1
axon cytoplasm	1	HSPB1
midbody	1	HSP90B1
cell-cell junction	1	AKT1
vesicle	2	AKT1, BGLAP
Cytoplasm, perinuclear region	1	PLCZ1
pore complex	1	BCL2
Cytoplasm, cytoskeleton, spindle	1	HSPB1
focal adhesion	3	CAT, HSP90B1, HSPB1
spindle	2	AKT1, HSPB1
Peroxisome	1	CAT
basement membrane	1	ACHE
Peroxisome matrix	1	CAT
peroxisomal matrix	1	CAT
peroxisomal membrane	1	CAT
Cell projection, dendritic spine	1	PTEN
Nucleus, PML body	2	MTOR, PTEN
PML body	2	MTOR, PTEN
Mitochondrion intermembrane space	1	AKT1
mitochondrial intermembrane space	1	AKT1
collagen-containing extracellular matrix	1	HSP90B1
Late endosome	1	INSR
receptor complex	1	INSR
Cell projection, neuron projection	1	PTEN
neuron projection	1	PTEN
ciliary basal body	1	AKT1
chromatin	1	RUNX2
cell projection	1	PTEN
cytoskeleton	1	HSPB1
Lipid-anchor, GPI-anchor	2	ACHE, TREH
nuclear envelope	1	MTOR
Endomembrane system	1	MTOR
endosome lumen	1	INS
Cornified envelope	1	HSPB1
Melanosome	1	HSP90B1
side of membrane	2	ACHE, TREH
myelin sheath	1	BCL2
sperm plasma membrane	1	HSP90B1
ficolin-1-rich granule lumen	1	CAT
proteasome complex	1	HSPB1
secretory granule lumen	2	CAT, INS
Golgi lumen	2	BGLAP, INS
endoplasmic reticulum lumen	4	BGLAP, HSP90B1, IL6, INS
phosphatidylinositol 3-kinase complex	1	PIK3CA
phosphatidylinositol 3-kinase complex, class IA	1	PIK3CA
transport vesicle	1	INS
Schmidt-Lanterman incisure	1	PTEN
Endoplasmic reticulum-Golgi intermediate compartment membrane	1	INS
Sarcoplasmic reticulum lumen	1	HSP90B1
synaptic cleft	1	ACHE
death-inducing signaling complex	1	CASP3
dendrite membrane	1	INSR
Cytoplasmic vesicle, phagosome	1	MTOR
endocytic vesicle lumen	1	HSP90B1
catalase complex	1	CAT
sperm head	1	PLCZ1
interleukin-6 receptor complex	1	IL6
insulin receptor complex	1	INSR
endoplasmic reticulum chaperone complex	1	HSP90B1
myelin sheath adaxonal region	1	PTEN
BAD-BCL-2 complex	1	BCL2
[Isoform alpha]: Secreted	1	PTEN
[Isoform H]: Cell membrane	1	ACHE
phosphatidylinositol 3-kinase complex, class IB	1	PIK3CA

文献列表

Susana Tavares Cotrim Ribeiro, Naiara Cássia Gancedo, Arildo José Braz de Oliveira, Regina Aparecida Correia Gonçalves. A comprehensive review of Pfaffia glomerata botany, ethnopharmacology, phytochemistry, biological activities, and biotechnology. Journal of ethnopharmacology. 2024 Jun; 328(?):118003. doi: 10.1016/j.jep.2024.118003. [PMID: 38484957]
Hai-Chao Wang, Ling Li, Jing-Hang Zhang, Zhi-Han Yao, Bao-Ping Pang. MicroRNA miR-7-5p targets MARK2 to control metamorphosis in Galeruca daurica. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2024 Jun; 272(?):110967. doi: 10.1016/j.cbpb.2024.110967. [PMID: 38521445]
Velislava Todorova, Stanislava Ivanova, Dzhevdet Chakarov, Krasimir Kraev, Kalin Ivanov. Ecdysterone and Turkesterone-Compounds with Prominent Potential in Sport and Healthy Nutrition. Nutrients. 2024 May; 16(9):. doi: 10.3390/nu16091382. [PMID: 38732627]
Yu-Xing Zhang, Qiao Tan, Lin Jin, Guo-Qing Li. Molecular characterization of the cytochrome P450 enzyme CYP18A1 in Henosepilachna vigintioctopunctata. Archives of insect biochemistry and physiology. 2024 Apr; 115(4):e22111. doi: 10.1002/arch.22111. [PMID: 38628055]
Haihui Xing, Guohua Chen, Faisal Raza, Hajra Zafar, Lei Xing, Qiaoyun Li, Ran Li, Shanshan Xu, Dan Chen. The Protective Effects of Ecdysterone on Cognitive Impairment through Regulating Akt/GSK-3β/Nrf2 Signaling Pathway and Oxidative Stress in Cognitive Mice Model and Aβ-Induced Cell Neurotoxicity. Frontiers in bioscience (Landmark edition). 2024 Mar; 29(3):109. doi: 10.31083/j.fbl2903109. [PMID: 38538266]
Yong Wang, Benjamin Buer, Cynthia L Goodman, David Kang, Tamra Reall, Susanne Dohn, Joseph Ringbauer, Yaofa Li, Sven Geibel, David Stanley. Indomethacin and 20-hydroxyecdysone influence protein expression in a Spodoptera frugiperda nervous system cell line. Archives of insect biochemistry and physiology. 2024 Feb; 115(2):e22089. doi: 10.1002/arch.22089. [PMID: 38409869]
Hugo Alarie, Nadia Côté, Luc Gaudreau, Magali Houde, Pedro A Segura. Are 20-hydroxyecdysone and related genes potential biomarkers of sublethal exposure to lipid-altering contaminants?. Environmental science and pollution research international. 2023 Dec; 30(60):126104-126115. doi: 10.1007/s11356-023-31087-2. [PMID: 38010540]
Kou Wang, Wen Liu, Xiao-Ping Wang. Dpp-mediated TGF-β signaling regulates vitellogenesis through 20-hydroxyecdysone signaling in the cabbage beetle, Colaphellus bowringi. Pesticide biochemistry and physiology. 2023 Dec; 197(?):105706. doi: 10.1016/j.pestbp.2023.105706. [PMID: 38072559]
Xinxin Gao, Jihong Zhang, Qilian Qin, Peipei Wu, Huan Zhang, Qian Meng. Metabolic changes during larval-pupal metamorphosis of Helicoverpa armigera. Insect science. 2023 Dec; 30(6):1663-1676. doi: 10.1111/1744-7917.13201. [PMID: 37200210]
Di Wen, Zhi Chen, Jiamin Wen, Qiangqiang Jia. Sterol Regulation of Development and 20-Hydroxyecdysone Biosynthetic and Signaling Genes in Drosophila melanogaster. Cells. 2023 Jun; 12(13):. doi: 10.3390/cells12131739. [PMID: 37443773]
Sheng-Yu Zhang, Han Gao, Ankarjan Askar, Xing-Peng Li, Guo-Cai Zhang, Tian-Zhong Jing, Hang Zou, Hao Guan, Yun-He Zhao, Chuan-Shan Zou. Steroid hormone 20-hydroxyecdysone disturbs fat body lipid metabolism and negatively regulates gluconeogenesis in Hyphantria cunea larvae. Insect science. 2023 Jun; 30(3):771-788. doi: 10.1111/1744-7917.13130. [PMID: 36342157]
Xue-Li Hou, Yu-Qi Gao, Jing-Hui Yang, Han-Wu Liu, Meng-Meng Bai, Zhen-Hai Wu, Chun-Huan Li, Jun-Mian Tian, Jin-Ming Gao. Phytoecdysteroids from Dianthus superbus L.: Structures and anti-neuroinflammatory evaluation. Phytochemistry. 2023 May; 212(?):113710. doi: 10.1016/j.phytochem.2023.113710. [PMID: 37178942]
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