Pterostilbene (BioDeep_00000230799)

 

Secondary id: BioDeep_00000003171, BioDeep_00000228184, BioDeep_00000821387

PANOMIX_OTCML-2023 Volatile Flavor Compounds natural product


代谢物信息卡片


trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene

化学式: C16H16O3 (256.10993859999996)
中文名称: 紫檀芪, 紫檀茋
谱图信息: 最多检出来源 Viridiplantae(plant) 0.49%

分子结构信息

SMILES: C1=C(OC)C=C(/C=C/C2=CC=C(O)C=C2)C=C1OC
InChI: InChI=1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+

描述信息

Pterostilbene is a stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3 and 5. It has a role as an antioxidant, an antineoplastic agent, a neurotransmitter, a plant metabolite, an apoptosis inducer, a neuroprotective agent, an anti-inflammatory agent, a radical scavenger and a hypoglycemic agent. It is a stilbenol, a member of methoxybenzenes and a diether. It derives from a hydride of a trans-stilbene.
Pterostilbene is a natural product found in Vitis rupestris, Pterocarpus marsupium, and other organisms with data available.
Pterostilbene is a naturally-derived stilbenoid structurally related to resveratrol, with potential antioxidant, anti-inflammatory, pro-apoptotic, antineoplastic and cytoprotective activities. Upon administration, pterostilbene exerts its anti-oxidant activity by scavenging reactive oxygen species (ROS), thereby preventing oxidative stress and ROS-induced cell damage. It may also activate the nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated pathway and increase the expression of various antioxidant enzymes, such as superoxide dismutase (SOD). In addition, pterostilbene is able to inhibit inflammation by reducing the expression of various inflammatory mediators, such as interleukin (IL) 1beta, tumor necrosis factor alpha (TNF-a), inducible nitric oxide synthase (iNOS), cyclooxygenases (COX), and nuclear factor kappa B (NF-kB). It also inhibits or prevents the activation of many signaling pathways involved in carcinogenesis, and increases expression of various tumor suppressor genes while decreasing expression of certain tumor promoting genes. It also directly induces apoptosis in tumor cells.
See also: Pterocarpus marsupium wood (part of).
A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3 and 5.
C26170 - Protective Agent > C275 - Antioxidant
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].

同义名列表

65 个代谢物同义名

trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene; 4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]phenol;Pterostilbene; Phenol, 4-(2-(3,5-dimethoxyphenyl)ethenyl)-, (E)-; phenol, 4-((1E)-2-(3,5-dimethoxyphenyl)ethenyl)-; Phenol, 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-; Phenol, 4-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-; 4-?[2-?(3,?5-?dimethoxyphenyl)?ethenyl]?-Phenol; 4-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol; 4-((1E)-2-(3,5-DIMETHOXYPHENYL)ETHENYL)PHENOL; 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol; 4trans-(2-(3,5-dimethoxyphenyl)ethenyl)phenol; 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol; 4-((E)-2-(3,5-dimethoxyphenyl)ethenyl)phenol; (E)-1-hydroxy-4-(3,5-dimethoxy)styrylbenzene; E 4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol; Phenol, 4-[2-(3,5-dimethoxyphenyl)ethenyl]-; 4-((E)-2-(3,5-dimethoxyphenyl)vinyl)phenol; 4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]phenol; Phenol,4-[2-(3,5-dmethoxyphenyl)ethenyl]-; 4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol; 4-[2-(3,5-dimethoxyphenyl)ethenyl]phenol; 4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol; 3,5-Dimethoxy-4-hydroxyl-trans-stilbene; 3,5-dimethoxy-4-hydroxy-trans-stilbene; 4-Hydroxy-3,5-dimethoxy-trans-stilbene; trans-3,5-dimethoxy-4-hydroxystilbene; Pterostilbene, Pterocarpus marsupium; (E)-4-hydroxy-3,5-dimethoxystilbene; Pterostilbene, >=97\\% (HPLC), solid; (E)-4-(3,5-dimethoxystyryl)phenol; 4-Stilbenol, 3,5-dimethoxy-, (E)-; 4-hydroxy-3,5-dimethoxy stilbene; 4-hydroxy-3,5-dimethoxystilbene; 3,5-Dimethoxy-4-hydroxystilbene; 3,5-dimethoxy-4trans-stilbenol; (E)-3,5-dimethoxy-4-stilbenol; 4-(3,5-Dimethoxystyryl)phenol; 3,5-dimethoxy-4E-stilbenol; 3,5-dimethoxy-resveratrol; 3,5-Dimethoxy-4-stilbenol; PTEROSTILBENE [WHO-DD]; pterostilbene, (E)-; trans-pterostilbene; (Z)-Pterostilbene; Tero-STILL-bean; UNII-26R60S6A5I; Pterostilbene; MEGxp0_000345; pterostilben; ACon1_000305; 26R60S6A5I; pTeroPure; 4-[2-(3,5-dimethoxyphenyl)vinyl]phenol; trans-3,5-Dimethoxy-4′-hydroxystilbene; Pterostilbene, i>Pterocarpus marsupium; 3,5-Dimethoxy-4′-hydroxystilbene; Pterocarpus marsupium; SMR000440694; MLS000863581; MLS000759434; P1499_SIGMA; NSC613735; 537-42-8; C10287; Pterostilbene



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

87 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuehan Zhang, Jiashun Li, Zhenhua Qiu, Linyan Huang, Sushan Yang, Jinfeng Li, Kunlang Li, Yueyun Liang, Xuanyu Liu, Zecheng Chen, Jing Li, Beixian Zhou. Insights into the mechanism of action of pterostilbene against influenza A virus-induced acute lung injury. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155534. doi: 10.1016/j.phymed.2024.155534. [PMID: 38583346]
  • Rashmi Patil, Urmila Aswar, Nishant Vyas. Pterostilbene alleviates cafeteria diet-induced obesity and underlying depression in adolescent male Swiss albino mice and affects insulin resistance, inflammation, HPA axis dysfunction and SIRT1 mediated leptin-ghrelin signaling. Hormones and behavior. 2024 May; 161(?):105504. doi: 10.1016/j.yhbeh.2024.105504. [PMID: 38354494]
  • Wencheng Di, Aizhen Zhao, Xiaoru Li, Junmin Chen, Yongbin Dai, Jiawen Li, Wangrui Lei, Yang Yang, Hongzhou Lu. Pterostilbene protects against H2 O2 -induced oxidative stress by regulating GAS6/Axl signaling in HL-1 cells. Cell biochemistry and function. 2024 Mar; 42(2):e3956. doi: 10.1002/cbf.3956. [PMID: 38403920]
  • Pouya Goleij, Pantea Majma Sanaye, Mehregan Babamohamadi, Mohammad Amin Khazeei Tabari, Roshanak Amirian, Aryan Rezaee, Hamed Mirzaei, Alan Prem Kumar, Gautam Sethi, Sarvin Sadreddini, Philippe Jeandet, Haroon Khan. Phytostilbenes in lymphoma: Focuses on the mechanistic and clinical prospects of resveratrol, pterostilbene, piceatannol, and pinosylvin. Leukemia research. 2024 03; 138(?):107464. doi: 10.1016/j.leukres.2024.107464. [PMID: 38422882]
  • Xiaoning Wei, Zhenbao Shen, Mengmeng Zhu, Mengyuan Fang, Shengnan Wang, Tingting Zhang, Baotong Zhang, Xiaoxiao Yang, Zhilin Lv, Yajun Duan, Meixiu Jiang, Chuanrui Ma, Qingshan Li, Yuanli Chen. The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation. International immunopharmacology. 2023 Nov; 125(Pt B):111198. doi: 10.1016/j.intimp.2023.111198. [PMID: 37952482]
  • Xin Qu, Lijuan Zhang, Lin Wang. Pterostilbene as a Therapeutic Alternative for Central Nervous System Disorders: A Review of the Current Status and Perspectives. Journal of agricultural and food chemistry. 2023 Oct; 71(40):14432-14457. doi: 10.1021/acs.jafc.3c06238. [PMID: 37786984]
  • Jiayi Dou, Haozhen Cui, Zhenyu Cui, Meiyan Xuan, Chong Gao, Zhaoxu Li, Lihua Lian, Jixing Nan, Yanling Wu. Pterostilbene exerts cytotoxicity on activated hepatic stellate cells by inhibiting excessive proliferation through the crosstalk of Sirt1 and STAT3 pathways. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Sep; ?(?):114042. doi: 10.1016/j.fct.2023.114042. [PMID: 37722617]
  • Zhi-Hong Yang, Ye-Ju Liu, Wei-Kang Ban, Hai-Bo Liu, Ling-Juan Lv, Bao-Yue Zhang, Ai-Lin Liu, Zi-Yu Hou, Juan Lu, Xi Chen, Yu-Yang You. Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation. Food & function. 2023 Aug; ?(?):. doi: 10.1039/d3fo02639f. [PMID: 37602757]
  • Weikang Ban, Xinyi Jiang, Lingjuan Lv, Yue Jiao, Jianpeng Huang, Zhihong Yang, Yuyang You. Illustrate the distribution and metabolic regulatory effects of pterostilbene in cerebral ischemia-reperfusion rat brain by mass spectrometry imaging and spatial metabolomics. Talanta. 2023 Aug; 266(Pt 2):125060. doi: 10.1016/j.talanta.2023.125060. [PMID: 37598445]
  • Rashmi Patil, Urmila Aswar, Nishant Vyas. Pterostilbene ameliorates type-2 diabetes mellitus - Induced depressive-like behavior by mitigating insulin resistance, inflammation and ameliorating HPA axis dysfunction in rat brain. Brain research. 2023 Jul; 1817(?):148494. doi: 10.1016/j.brainres.2023.148494. [PMID: 37478963]
  • Yong-Mei Hu, Yi-Rong Wang, Wen-Bin Zhao, Yan Yan Ding, Zheng-Rong Wu, Guang-Han Wang, Peng Deng, Shao-Yong Zhang, Jun-Xia An, Zhi-Jun Zhang, Xiong-Fei Luo, Ying-Qian Liu. Efficacy of pterostilbene suppression on Aspergillus flavus growth, aflatoxin B1 biosynthesis and potential mechanisms. International journal of food microbiology. 2023 Jul; 404(?):110318. doi: 10.1016/j.ijfoodmicro.2023.110318. [PMID: 37454507]
  • Zhuo Chen, Xing-Gang Fang, Xing-Rong Guo, Si-Qi Luan, Jiao Hua, Jie Luo. [Anti-glioma mechanism of pterostilbene by regulating apoptosis and GSDME-mediated pyroptosis pathways: a study based on network pharmacology and experimental research]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Jul; 48(13):3589-3601. doi: 10.19540/j.cnki.cjcmm.20230216.703. [PMID: 37474992]
  • Sara Aly, Amal H El-Kamel, Eman Sheta, Salma E El-Habashy. Chondroitin/Lactoferrin-dual functionalized pterostilbene-solid lipid nanoparticles as targeted breast cancer therapy. International journal of pharmaceutics. 2023 Jun; 642(?):123163. doi: 10.1016/j.ijpharm.2023.123163. [PMID: 37353100]
  • Xinyu Cai, Boqiang Li, Xue Li, Hui Dang, Di Wang, Zhifei Pei, Xuan Feng, Xueyan Ren, Qingjun Kong. Characteristic Structures of Different Stilbenes Distinguish the Impact on Ochratoxin A Biosynthesis Intermediate Pathway and Metabolites of Aspergillus carbonarius. Journal of agricultural and food chemistry. 2023 May; 71(21):7996-8007. doi: 10.1021/acs.jafc.3c00717. [PMID: 37192315]
  • Muhammed Majeed, Kalyanam Nagabhushanam, Shaji Paulose, Lakshmi Mundkur. A Short-Term Safety Evaluation of Silbinol®- an Extract from Pterocarpus marsupium in Healthy Adults- a Randomized, Double-Blind, Placebo-Controlled Study. Journal of evidence-based integrative medicine. 2023 Jan; 28(?):2515690X231198312. doi: 10.1177/2515690x231198312. [PMID: 37671486]
  • Bingyu Shen, Yeling Wang, Jiaqi Cheng, Yi Peng, Qiaoling Zhang, Zheng Li, Lilei Zhao, Xuming Deng, Haihua Feng. Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jan; 109(?):154561. doi: 10.1016/j.phymed.2022.154561. [PMID: 36610156]
  • Yanan Chen, Hao Zhang, Yue Li, Tian Wang. Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens. Oxidative medicine and cellular longevity. 2023; 2023(?):8258354. doi: 10.1155/2023/8258354. [PMID: 36733420]
  • Antonio González-Sarrías, Juan Carlos Espín-Aguilar, Salvador Romero-Reyes, Julio Puigcerver, Mateo Alajarín, José Berná, María Victoria Selma, Juan Carlos Espín. Main Determinants Affecting the Antiproliferative Activity of Stilbenes and Their Gut Microbiota Metabolites in Colon Cancer Cells: A Structure-Activity Relationship Study. International journal of molecular sciences. 2022 Dec; 23(23):. doi: 10.3390/ijms232315102. [PMID: 36499424]
  • Yue Li, Hao Zhang, Feng Tu, Jing Cao, Xiang Hou, Yanan Chen, Junshu Yan. Effects of resveratrol and its derivative pterostilbene on hepatic injury and immunological stress of weaned piglets challenged with lipopolysaccharide. Journal of animal science. 2022 Dec; 100(12):. doi: 10.1093/jas/skac339. [PMID: 36242589]
  • Ayesha Amin, Muhammad Furqan Akhtar, Ammara Saleem, Ali Sharif, Shahid Shah, Muhammad Imran Khan, Fareeha Anwar, Ghulam Abbas, Hafiz Muhammad Zubair, Muhammad Farhan Sohail. Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats. Inflammopharmacology. 2022 Dec; 30(6):2285-2300. doi: 10.1007/s10787-022-01069-w. [PMID: 36138303]
  • Jiahong Sun, Wenqing Ding, Xue Liu, Min Zhao, Bo Xi. Serum metabolites of hypertension among Chinese adolescents aged 12-17 years. Journal of human hypertension. 2022 10; 36(10):925-932. doi: 10.1038/s41371-021-00602-8. [PMID: 34480101]
  • Sanjushree Nagarajan, Sundhar Mohandas, Kumar Ganesan, Baojun Xu, Kunka Mohanram Ramkumar. New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196316. [PMID: 36234852]
  • Ryan W Dellinger, Holly E Holmes, Tina Hu-Seliger, Rodney W Butt, Stephen A Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente. Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial. Hepatology (Baltimore, Md.). 2022 Sep; ?(?):. doi: 10.1002/hep.32778. [PMID: 36082508]
  • Yue Zhang, Lei Ni, Shihao Chen, Yafei Qin, Xing Ding, Jinhua Li, Yu Pan, Xingguo Zhang. Pterostilbene production of tomato transformed with resveratrol synthase and resveratrol O-methyltransferase genes. Plant science : an international journal of experimental plant biology. 2022 Sep; 322(?):111343. doi: 10.1016/j.plantsci.2022.111343. [PMID: 35690048]
  • Wei Gu, Linquan Yang, Xing Wang, Jianlin Geng, Xiaolong Li, Kunjie Zheng, Yunpeng Guan, Xiaoyu Hou, Chao Wang, Guangyao Song. Pterostilbene, a resveratrol derivative, improves ectopic lipid deposition in the kidneys of mice induced by a high-fat diet. Kidney & blood pressure research. 2022 Jun; ?(?):. doi: 10.1159/000525385. [PMID: 35717941]
  • Lamia A Heikal, Amal H El-Kamel, Radwa A Mehanna, Hoda M Khalifa, Passainte S Hassaan. Improved oral nutraceutical-based intervention for the management of obesity: pterostilbene-loaded chitosan nanoparticles. Nanomedicine (London, England). 2022 06; 17(15):1055-1075. doi: 10.2217/nnm-2022-0158. [PMID: 36066036]
  • Chuan-Teng Liu, Ying-Chyi Song, Tsai-Chen Wu, Ko-Chieh Shiung, I-Hsuan Chen, Tung-Ti Chang, Shinn-Jye Liang, Hung-Rong Yen. Targeting glycolysis in Th2 cells by pterostilbene attenuates clinical severities in an asthmatic mouse model and IL-4 production in peripheral blood from asthmatic patients. Immunology. 2022 06; 166(2):222-237. doi: 10.1111/imm.13469. [PMID: 35285025]
  • Jikai Xu, Jingyu Liu, Yan Mi, Ting Zhao, Danyang Mu, Qingqi Meng, Feng Wang, Ning Li, Yue Hou. Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia. Journal of agricultural and food chemistry. 2022 May; 70(19):5896-5910. doi: 10.1021/acs.jafc.2c01219. [PMID: 35532888]
  • Ze Rui, Ling Zhang, Xuefei Li, Jinxue Han, Yufeng Yuan, Hui Ding, Yang Liu, Xiaolin Ding. Pterostilbene exert an anti-arthritic effect by attenuating inflammation, oxidative stress, and alteration of gut microbiota. Journal of food biochemistry. 2022 05; 46(5):e14011. doi: 10.1111/jfbc.14011. [PMID: 35060152]
  • Hui-Yun Tsai, Yu-Yuan Shih, Yao-Tsung Yeh, Cheng-Hsieh Huang, Chorng-An Liao, Chun-Yi Hu, Kalyanam Nagabhushanam, Chi-Tang Ho, Yu-Kuo Chen. Pterostilbene and Its Derivative 3'-Hydroxypterostilbene Ameliorated Nonalcoholic Fatty Liver Disease Through Synergistic Modulation of the Gut Microbiota and SIRT1/AMPK Signaling Pathway. Journal of agricultural and food chemistry. 2022 Apr; 70(16):4966-4980. doi: 10.1021/acs.jafc.2c00641. [PMID: 35416649]
  • Pu-Ying Qi, Tai-Hong Zhang, Yu-Mei Feng, Ming-Wei Wang, Wu-Bin Shao, Dan Zeng, Lin-Hong Jin, Pei-Yi Wang, Xiang Zhou, Song Yang. Exploring an Innovative Strategy for Suppressing Bacterial Plant Disease: Excavated Novel Isopropanolamine-Tailored Pterostilbene Derivatives as Potential Antibiofilm Agents. Journal of agricultural and food chemistry. 2022 Apr; 70(16):4899-4911. doi: 10.1021/acs.jafc.2c00590. [PMID: 35437986]
  • Yue Sun, Qi Wang, Xian Wu, Fang Li, Mingyue Song, Minqi Wang, Xiaokun Cai, Zhengze Li, Zili Gao, Jinkai Zheng, Ce Qi, Jin Sun, Hang Xiao. Gastrointestinal biotransformation and tissue distribution of pterostilbene after long-term dietary administration in mice. Food chemistry. 2022 Mar; 372(?):131213. doi: 10.1016/j.foodchem.2021.131213. [PMID: 34638060]
  • Magda I Mohamad, Islam A Desoky, Kamelia Ahmed Zaki, Doaa R Sadek, Samar Kamal Kassim, Dalia Abdel-Wahab Mohamed. Pterostilbene ameliorates the disrupted Adars expression and improves liver fibrosis in DEN-induced liver injury in Wistar rats: A novel potential effect. Gene. 2022 Mar; 813(?):146124. doi: 10.1016/j.gene.2021.146124. [PMID: 34921950]
  • Qiangqiang Shi, Guangfen Zhao, Susu Wei, Chuanlong Guo, Xianggen Wu, Robert Chunhua Zhao, Guohu Di. Pterostilbene alleviates liver ischemia/reperfusion injury via PINK1-mediated mitophagy. Journal of pharmacological sciences. 2022 Jan; 148(1):19-30. doi: 10.1016/j.jphs.2021.09.005. [PMID: 34924126]
  • Ting Wang, Kaiju Xu, Liyun Zhao, Rongsheng Tong, Liang Xiong, Jianyou Shi. Recent research and development of NDM-1 inhibitors. European journal of medicinal chemistry. 2021 Nov; 223(?):113667. doi: 10.1016/j.ejmech.2021.113667. [PMID: 34225181]
  • Viney Kumar, Swati Haldar, Neeladri Singha Das, Souvik Ghosh, Poonam Dhankhar, Debabrata Sircar, Partha Roy. Pterostilbene-isothiocyanate inhibits breast cancer metastasis by selectively blocking IKK-β/NEMO interaction in cancer cells. Biochemical pharmacology. 2021 10; 192(?):114717. doi: 10.1016/j.bcp.2021.114717. [PMID: 34352281]
  • Mariana Juste Contin Gomes, Nikolai Kolba, Nikita Agarwal, Dean Kim, Adi Eshel, Omry Koren, Elad Tako. Modifications in the Intestinal Functionality, Morphology and Microbiome Following Intra-Amniotic Administration (Gallus gallus) of Grape (Vitis vinifera) Stilbenes (Resveratrol and Pterostilbene). Nutrients. 2021 Sep; 13(9):. doi: 10.3390/nu13093247. [PMID: 34579124]
  • Lingyan Jiang, Renlong Yin, Qiaofei Zheng, Chunyong He, Huichao Chang. High-resolution mass spectrometry-based methodology for the identification of the metabolites of pterostilbene produced by rat, dog and human hepatocytes. Biomedical chromatography : BMC. 2021 Sep; 35(9):e5138. doi: 10.1002/bmc.5138. [PMID: 33830523]
  • Wenzhe Yu, Lida Fan, Mingfu Wang, Bin Cao, Xiaoqian Hu. Pterostilbene Improves Insulin Resistance Caused by Advanced Glycation End Products (AGEs) in Hepatocytes and Mice. Molecular nutrition & food research. 2021 08; 65(15):e2100321. doi: 10.1002/mnfr.202100321. [PMID: 34085383]
  • Bram M Ter Ellen, Nilima Dinesh Kumar, Ellen M Bouma, Berit Troost, Denise P I van de Pol, Heidi H van der Ende-Metselaar, Leonie Apperloo, Djoke van Gosliga, Maarten van den Berge, Martijn C Nawijn, Peter H J van der Voort, Jill Moser, Izabela A Rodenhuis-Zybert, Jolanda M Smit. Resveratrol and Pterostilbene Inhibit SARS-CoV-2 Replication in Air-Liquid Interface Cultured Human Primary Bronchial Epithelial Cells. Viruses. 2021 07; 13(7):. doi: 10.3390/v13071335. [PMID: 34372541]
  • Dan Tang, Wei Xiao, Wen-Ting Gu, Zhi-Tong Zhang, Shu-Hong Xu, Zhi-Quan Chen, You-Hua Xu, Lu-Yong Zhang, Shu-Mei Wang, Hong Nie. Pterostilbene prevents methylglyoxal-induced cytotoxicity in endothelial cells by regulating glyoxalase, oxidative stress and apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2021 Jul; 153(?):112244. doi: 10.1016/j.fct.2021.112244. [PMID: 33930484]
  • Mina T Kelleni. Resveratrol-zinc nanoparticles or pterostilbene-zinc: Potential COVID-19 mono and adjuvant therapy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jul; 139(?):111626. doi: 10.1016/j.biopha.2021.111626. [PMID: 33894625]
  • Ping-Yun Fan-Jiang, Pei-Sheng Lee, Kalyanam Nagabhushanam, Chi-Tang Ho, Min-Hsiung Pan. Pterostilbene Attenuates High-Fat Diet and Dextran Sulfate Sodium-Induced Colitis via Suppressing Inflammation and Intestinal Fibrosis in Mice. Journal of agricultural and food chemistry. 2021 Jun; 69(25):7093-7103. doi: 10.1021/acs.jafc.1c02783. [PMID: 34152136]
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