Pterostilbene (BioDeep_00000230799)

 

Secondary id: BioDeep_00000003171, BioDeep_00000228184

PANOMIX_OTCML-2023


代谢物信息卡片


trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene

化学式: C16H16O3 (256.10993859999996)
中文名称: 紫檀茋, 紫檀芪, 紫檀芪
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 0.57%

分子结构信息

SMILES: C1=C(OC)C=C(/C=C/C2=CC=C(O)C=C2)C=C1OC
InChI: InChI=1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+

描述信息

Pterostilbene is a stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3 and 5. It has a role as an antioxidant, an antineoplastic agent, a neurotransmitter, a plant metabolite, an apoptosis inducer, a neuroprotective agent, an anti-inflammatory agent, a radical scavenger and a hypoglycemic agent. It is a stilbenol, a member of methoxybenzenes and a diether. It derives from a hydride of a trans-stilbene.
Pterostilbene is a natural product found in Vitis rupestris, Pterocarpus marsupium, and other organisms with data available.
Pterostilbene is a naturally-derived stilbenoid structurally related to resveratrol, with potential antioxidant, anti-inflammatory, pro-apoptotic, antineoplastic and cytoprotective activities. Upon administration, pterostilbene exerts its anti-oxidant activity by scavenging reactive oxygen species (ROS), thereby preventing oxidative stress and ROS-induced cell damage. It may also activate the nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated pathway and increase the expression of various antioxidant enzymes, such as superoxide dismutase (SOD). In addition, pterostilbene is able to inhibit inflammation by reducing the expression of various inflammatory mediators, such as interleukin (IL) 1beta, tumor necrosis factor alpha (TNF-a), inducible nitric oxide synthase (iNOS), cyclooxygenases (COX), and nuclear factor kappa B (NF-kB). It also inhibits or prevents the activation of many signaling pathways involved in carcinogenesis, and increases expression of various tumor suppressor genes while decreasing expression of certain tumor promoting genes. It also directly induces apoptosis in tumor cells.
See also: Pterocarpus marsupium wood (part of).
A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3 and 5.
C26170 - Protective Agent > C275 - Antioxidant
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].
Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].

同义名列表

64 个代谢物同义名

trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene; 4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]phenol;Pterostilbene; Phenol, 4-(2-(3,5-dimethoxyphenyl)ethenyl)-, (E)-; phenol, 4-((1E)-2-(3,5-dimethoxyphenyl)ethenyl)-; Phenol, 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-; Phenol, 4-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-; 4-?[2-?(3,?5-?dimethoxyphenyl)?ethenyl]?-Phenol; 4-[(E)-2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol; 4-((1E)-2-(3,5-DIMETHOXYPHENYL)ETHENYL)PHENOL; 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol; 4trans-(2-(3,5-dimethoxyphenyl)ethenyl)phenol; 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol; 4-((E)-2-(3,5-dimethoxyphenyl)ethenyl)phenol; (E)-1-hydroxy-4-(3,5-dimethoxy)styrylbenzene; E 4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol; Phenol, 4-[2-(3,5-dimethoxyphenyl)ethenyl]-; 4-((E)-2-(3,5-dimethoxyphenyl)vinyl)phenol; 4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]phenol; Phenol,4-[2-(3,5-dmethoxyphenyl)ethenyl]-; 4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenol; 4-[2-(3,5-dimethoxyphenyl)ethenyl]phenol; 4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol; 3,5-Dimethoxy-4-hydroxyl-trans-stilbene; 3,5-dimethoxy-4-hydroxy-trans-stilbene; 4-Hydroxy-3,5-dimethoxy-trans-stilbene; trans-3,5-dimethoxy-4-hydroxystilbene; Pterostilbene, Pterocarpus marsupium; (E)-4-hydroxy-3,5-dimethoxystilbene; Pterostilbene, >=97\\% (HPLC), solid; (E)-4-(3,5-dimethoxystyryl)phenol; 4-Stilbenol, 3,5-dimethoxy-, (E)-; 4-hydroxy-3,5-dimethoxy stilbene; 4-hydroxy-3,5-dimethoxystilbene; 3,5-Dimethoxy-4-hydroxystilbene; 3,5-dimethoxy-4trans-stilbenol; (E)-3,5-dimethoxy-4-stilbenol; 4-(3,5-Dimethoxystyryl)phenol; 3,5-dimethoxy-4E-stilbenol; 3,5-dimethoxy-resveratrol; 3,5-Dimethoxy-4-stilbenol; PTEROSTILBENE [WHO-DD]; pterostilbene, (E)-; trans-pterostilbene; (Z)-Pterostilbene; Tero-STILL-bean; UNII-26R60S6A5I; Pterostilbene; MEGxp0_000345; pterostilben; ACon1_000305; 26R60S6A5I; pTeroPure; 4-[2-(3,5-dimethoxyphenyl)vinyl]phenol; trans-3,5-Dimethoxy-4′-hydroxystilbene; Pterostilbene, i>Pterocarpus marsupium; 3,5-Dimethoxy-4′-hydroxystilbene; Pterocarpus marsupium; SMR000440694; MLS000863581; MLS000759434; P1499_SIGMA; NSC613735; 537-42-8; C10287



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

40 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuehan Zhang, Jiashun Li, Zhenhua Qiu, Linyan Huang, Sushan Yang, Jinfeng Li, Kunlang Li, Yueyun Liang, Xuanyu Liu, Zecheng Chen, Jing Li, Beixian Zhou. Insights into the mechanism of action of pterostilbene against influenza A virus-induced acute lung injury. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155534. doi: 10.1016/j.phymed.2024.155534. [PMID: 38583346]
  • Rashmi Patil, Urmila Aswar, Nishant Vyas. Pterostilbene alleviates cafeteria diet-induced obesity and underlying depression in adolescent male Swiss albino mice and affects insulin resistance, inflammation, HPA axis dysfunction and SIRT1 mediated leptin-ghrelin signaling. Hormones and behavior. 2024 May; 161(?):105504. doi: 10.1016/j.yhbeh.2024.105504. [PMID: 38354494]
  • Wencheng Di, Aizhen Zhao, Xiaoru Li, Junmin Chen, Yongbin Dai, Jiawen Li, Wangrui Lei, Yang Yang, Hongzhou Lu. Pterostilbene protects against H2 O2 -induced oxidative stress by regulating GAS6/Axl signaling in HL-1 cells. Cell biochemistry and function. 2024 Mar; 42(2):e3956. doi: 10.1002/cbf.3956. [PMID: 38403920]
  • Pouya Goleij, Pantea Majma Sanaye, Mehregan Babamohamadi, Mohammad Amin Khazeei Tabari, Roshanak Amirian, Aryan Rezaee, Hamed Mirzaei, Alan Prem Kumar, Gautam Sethi, Sarvin Sadreddini, Philippe Jeandet, Haroon Khan. Phytostilbenes in lymphoma: Focuses on the mechanistic and clinical prospects of resveratrol, pterostilbene, piceatannol, and pinosylvin. Leukemia research. 2024 03; 138(?):107464. doi: 10.1016/j.leukres.2024.107464. [PMID: 38422882]
  • Xiaoning Wei, Zhenbao Shen, Mengmeng Zhu, Mengyuan Fang, Shengnan Wang, Tingting Zhang, Baotong Zhang, Xiaoxiao Yang, Zhilin Lv, Yajun Duan, Meixiu Jiang, Chuanrui Ma, Qingshan Li, Yuanli Chen. The pterostilbene-dihydropyrazole derivative Ptd-1 ameliorates vascular calcification by regulating inflammation. International immunopharmacology. 2023 Nov; 125(Pt B):111198. doi: 10.1016/j.intimp.2023.111198. [PMID: 37952482]
  • Xin Qu, Lijuan Zhang, Lin Wang. Pterostilbene as a Therapeutic Alternative for Central Nervous System Disorders: A Review of the Current Status and Perspectives. Journal of agricultural and food chemistry. 2023 Oct; 71(40):14432-14457. doi: 10.1021/acs.jafc.3c06238. [PMID: 37786984]
  • Jiayi Dou, Haozhen Cui, Zhenyu Cui, Meiyan Xuan, Chong Gao, Zhaoxu Li, Lihua Lian, Jixing Nan, Yanling Wu. Pterostilbene exerts cytotoxicity on activated hepatic stellate cells by inhibiting excessive proliferation through the crosstalk of Sirt1 and STAT3 pathways. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Sep; ?(?):114042. doi: 10.1016/j.fct.2023.114042. [PMID: 37722617]
  • Zhi-Hong Yang, Ye-Ju Liu, Wei-Kang Ban, Hai-Bo Liu, Ling-Juan Lv, Bao-Yue Zhang, Ai-Lin Liu, Zi-Yu Hou, Juan Lu, Xi Chen, Yu-Yang You. Pterostilbene alleviated cerebral ischemia/reperfusion-induced blood-brain barrier dysfunction via inhibiting early endothelial cytoskeleton reorganization and late basement membrane degradation. Food & function. 2023 Aug; ?(?):. doi: 10.1039/d3fo02639f. [PMID: 37602757]
  • Weikang Ban, Xinyi Jiang, Lingjuan Lv, Yue Jiao, Jianpeng Huang, Zhihong Yang, Yuyang You. Illustrate the distribution and metabolic regulatory effects of pterostilbene in cerebral ischemia-reperfusion rat brain by mass spectrometry imaging and spatial metabolomics. Talanta. 2023 Aug; 266(Pt 2):125060. doi: 10.1016/j.talanta.2023.125060. [PMID: 37598445]
  • Rashmi Patil, Urmila Aswar, Nishant Vyas. Pterostilbene ameliorates type-2 diabetes mellitus - Induced depressive-like behavior by mitigating insulin resistance, inflammation and ameliorating HPA axis dysfunction in rat brain. Brain research. 2023 Jul; 1817(?):148494. doi: 10.1016/j.brainres.2023.148494. [PMID: 37478963]
  • Yong-Mei Hu, Yi-Rong Wang, Wen-Bin Zhao, Yan Yan Ding, Zheng-Rong Wu, Guang-Han Wang, Peng Deng, Shao-Yong Zhang, Jun-Xia An, Zhi-Jun Zhang, Xiong-Fei Luo, Ying-Qian Liu. Efficacy of pterostilbene suppression on Aspergillus flavus growth, aflatoxin B1 biosynthesis and potential mechanisms. International journal of food microbiology. 2023 Jul; 404(?):110318. doi: 10.1016/j.ijfoodmicro.2023.110318. [PMID: 37454507]
  • Zhuo Chen, Xing-Gang Fang, Xing-Rong Guo, Si-Qi Luan, Jiao Hua, Jie Luo. [Anti-glioma mechanism of pterostilbene by regulating apoptosis and GSDME-mediated pyroptosis pathways: a study based on network pharmacology and experimental research]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Jul; 48(13):3589-3601. doi: 10.19540/j.cnki.cjcmm.20230216.703. [PMID: 37474992]
  • Sara Aly, Amal H El-Kamel, Eman Sheta, Salma E El-Habashy. Chondroitin/Lactoferrin-dual functionalized pterostilbene-solid lipid nanoparticles as targeted breast cancer therapy. International journal of pharmaceutics. 2023 Jun; 642(?):123163. doi: 10.1016/j.ijpharm.2023.123163. [PMID: 37353100]
  • Xinyu Cai, Boqiang Li, Xue Li, Hui Dang, Di Wang, Zhifei Pei, Xuan Feng, Xueyan Ren, Qingjun Kong. Characteristic Structures of Different Stilbenes Distinguish the Impact on Ochratoxin A Biosynthesis Intermediate Pathway and Metabolites of Aspergillus carbonarius. Journal of agricultural and food chemistry. 2023 May; 71(21):7996-8007. doi: 10.1021/acs.jafc.3c00717. [PMID: 37192315]
  • Muhammed Majeed, Kalyanam Nagabhushanam, Shaji Paulose, Lakshmi Mundkur. A Short-Term Safety Evaluation of Silbinol®- an Extract from Pterocarpus marsupium in Healthy Adults- a Randomized, Double-Blind, Placebo-Controlled Study. Journal of evidence-based integrative medicine. 2023 Jan; 28(?):2515690X231198312. doi: 10.1177/2515690x231198312. [PMID: 37671486]
  • Bingyu Shen, Yeling Wang, Jiaqi Cheng, Yi Peng, Qiaoling Zhang, Zheng Li, Lilei Zhao, Xuming Deng, Haihua Feng. Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jan; 109(?):154561. doi: 10.1016/j.phymed.2022.154561. [PMID: 36610156]
  • Yanan Chen, Hao Zhang, Yue Li, Tian Wang. Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens. Oxidative medicine and cellular longevity. 2023; 2023(?):8258354. doi: 10.1155/2023/8258354. [PMID: 36733420]
  • Antonio González-Sarrías, Juan Carlos Espín-Aguilar, Salvador Romero-Reyes, Julio Puigcerver, Mateo Alajarín, José Berná, María Victoria Selma, Juan Carlos Espín. Main Determinants Affecting the Antiproliferative Activity of Stilbenes and Their Gut Microbiota Metabolites in Colon Cancer Cells: A Structure-Activity Relationship Study. International journal of molecular sciences. 2022 Dec; 23(23):. doi: 10.3390/ijms232315102. [PMID: 36499424]
  • Yue Li, Hao Zhang, Feng Tu, Jing Cao, Xiang Hou, Yanan Chen, Junshu Yan. Effects of resveratrol and its derivative pterostilbene on hepatic injury and immunological stress of weaned piglets challenged with lipopolysaccharide. Journal of animal science. 2022 Dec; 100(12):. doi: 10.1093/jas/skac339. [PMID: 36242589]
  • Ayesha Amin, Muhammad Furqan Akhtar, Ammara Saleem, Ali Sharif, Shahid Shah, Muhammad Imran Khan, Fareeha Anwar, Ghulam Abbas, Hafiz Muhammad Zubair, Muhammad Farhan Sohail. Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats. Inflammopharmacology. 2022 Dec; 30(6):2285-2300. doi: 10.1007/s10787-022-01069-w. [PMID: 36138303]
  • Jiahong Sun, Wenqing Ding, Xue Liu, Min Zhao, Bo Xi. Serum metabolites of hypertension among Chinese adolescents aged 12-17 years. Journal of human hypertension. 2022 10; 36(10):925-932. doi: 10.1038/s41371-021-00602-8. [PMID: 34480101]
  • Sanjushree Nagarajan, Sundhar Mohandas, Kumar Ganesan, Baojun Xu, Kunka Mohanram Ramkumar. New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects. Molecules (Basel, Switzerland). 2022 Sep; 27(19):. doi: 10.3390/molecules27196316. [PMID: 36234852]
  • Ryan W Dellinger, Holly E Holmes, Tina Hu-Seliger, Rodney W Butt, Stephen A Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente. Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial. Hepatology (Baltimore, Md.). 2022 Sep; ?(?):. doi: 10.1002/hep.32778. [PMID: 36082508]
  • Yue Zhang, Lei Ni, Shihao Chen, Yafei Qin, Xing Ding, Jinhua Li, Yu Pan, Xingguo Zhang. Pterostilbene production of tomato transformed with resveratrol synthase and resveratrol O-methyltransferase genes. Plant science : an international journal of experimental plant biology. 2022 Sep; 322(?):111343. doi: 10.1016/j.plantsci.2022.111343. [PMID: 35690048]
  • Wei Gu, Linquan Yang, Xing Wang, Jianlin Geng, Xiaolong Li, Kunjie Zheng, Yunpeng Guan, Xiaoyu Hou, Chao Wang, Guangyao Song. Pterostilbene, a resveratrol derivative, improves ectopic lipid deposition in the kidneys of mice induced by a high-fat diet. Kidney & blood pressure research. 2022 Jun; ?(?):. doi: 10.1159/000525385. [PMID: 35717941]
  • Lamia A Heikal, Amal H El-Kamel, Radwa A Mehanna, Hoda M Khalifa, Passainte S Hassaan. Improved oral nutraceutical-based intervention for the management of obesity: pterostilbene-loaded chitosan nanoparticles. Nanomedicine (London, England). 2022 06; 17(15):1055-1075. doi: 10.2217/nnm-2022-0158. [PMID: 36066036]
  • Chuan-Teng Liu, Ying-Chyi Song, Tsai-Chen Wu, Ko-Chieh Shiung, I-Hsuan Chen, Tung-Ti Chang, Shinn-Jye Liang, Hung-Rong Yen. Targeting glycolysis in Th2 cells by pterostilbene attenuates clinical severities in an asthmatic mouse model and IL-4 production in peripheral blood from asthmatic patients. Immunology. 2022 06; 166(2):222-237. doi: 10.1111/imm.13469. [PMID: 35285025]
  • Jikai Xu, Jingyu Liu, Yan Mi, Ting Zhao, Danyang Mu, Qingqi Meng, Feng Wang, Ning Li, Yue Hou. Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia. Journal of agricultural and food chemistry. 2022 May; 70(19):5896-5910. doi: 10.1021/acs.jafc.2c01219. [PMID: 35532888]
  • Ze Rui, Ling Zhang, Xuefei Li, Jinxue Han, Yufeng Yuan, Hui Ding, Yang Liu, Xiaolin Ding. Pterostilbene exert an anti-arthritic effect by attenuating inflammation, oxidative stress, and alteration of gut microbiota. Journal of food biochemistry. 2022 05; 46(5):e14011. doi: 10.1111/jfbc.14011. [PMID: 35060152]
  • Hui-Yun Tsai, Yu-Yuan Shih, Yao-Tsung Yeh, Cheng-Hsieh Huang, Chorng-An Liao, Chun-Yi Hu, Kalyanam Nagabhushanam, Chi-Tang Ho, Yu-Kuo Chen. Pterostilbene and Its Derivative 3'-Hydroxypterostilbene Ameliorated Nonalcoholic Fatty Liver Disease Through Synergistic Modulation of the Gut Microbiota and SIRT1/AMPK Signaling Pathway. Journal of agricultural and food chemistry. 2022 Apr; 70(16):4966-4980. doi: 10.1021/acs.jafc.2c00641. [PMID: 35416649]
  • Pu-Ying Qi, Tai-Hong Zhang, Yu-Mei Feng, Ming-Wei Wang, Wu-Bin Shao, Dan Zeng, Lin-Hong Jin, Pei-Yi Wang, Xiang Zhou, Song Yang. Exploring an Innovative Strategy for Suppressing Bacterial Plant Disease: Excavated Novel Isopropanolamine-Tailored Pterostilbene Derivatives as Potential Antibiofilm Agents. Journal of agricultural and food chemistry. 2022 Apr; 70(16):4899-4911. doi: 10.1021/acs.jafc.2c00590. [PMID: 35437986]
  • Yue Sun, Qi Wang, Xian Wu, Fang Li, Mingyue Song, Minqi Wang, Xiaokun Cai, Zhengze Li, Zili Gao, Jinkai Zheng, Ce Qi, Jin Sun, Hang Xiao. Gastrointestinal biotransformation and tissue distribution of pterostilbene after long-term dietary administration in mice. Food chemistry. 2022 Mar; 372(?):131213. doi: 10.1016/j.foodchem.2021.131213. [PMID: 34638060]
  • Magda I Mohamad, Islam A Desoky, Kamelia Ahmed Zaki, Doaa R Sadek, Samar Kamal Kassim, Dalia Abdel-Wahab Mohamed. Pterostilbene ameliorates the disrupted Adars expression and improves liver fibrosis in DEN-induced liver injury in Wistar rats: A novel potential effect. Gene. 2022 Mar; 813(?):146124. doi: 10.1016/j.gene.2021.146124. [PMID: 34921950]
  • Qiangqiang Shi, Guangfen Zhao, Susu Wei, Chuanlong Guo, Xianggen Wu, Robert Chunhua Zhao, Guohu Di. Pterostilbene alleviates liver ischemia/reperfusion injury via PINK1-mediated mitophagy. Journal of pharmacological sciences. 2022 Jan; 148(1):19-30. doi: 10.1016/j.jphs.2021.09.005. [PMID: 34924126]
  • Ting Wang, Kaiju Xu, Liyun Zhao, Rongsheng Tong, Liang Xiong, Jianyou Shi. Recent research and development of NDM-1 inhibitors. European journal of medicinal chemistry. 2021 Nov; 223(?):113667. doi: 10.1016/j.ejmech.2021.113667. [PMID: 34225181]
  • Viney Kumar, Swati Haldar, Neeladri Singha Das, Souvik Ghosh, Poonam Dhankhar, Debabrata Sircar, Partha Roy. Pterostilbene-isothiocyanate inhibits breast cancer metastasis by selectively blocking IKK-β/NEMO interaction in cancer cells. Biochemical pharmacology. 2021 10; 192(?):114717. doi: 10.1016/j.bcp.2021.114717. [PMID: 34352281]
  • Mariana Juste Contin Gomes, Nikolai Kolba, Nikita Agarwal, Dean Kim, Adi Eshel, Omry Koren, Elad Tako. Modifications in the Intestinal Functionality, Morphology and Microbiome Following Intra-Amniotic Administration (Gallus gallus) of Grape (Vitis vinifera) Stilbenes (Resveratrol and Pterostilbene). Nutrients. 2021 Sep; 13(9):. doi: 10.3390/nu13093247. [PMID: 34579124]
  • Lingyan Jiang, Renlong Yin, Qiaofei Zheng, Chunyong He, Huichao Chang. High-resolution mass spectrometry-based methodology for the identification of the metabolites of pterostilbene produced by rat, dog and human hepatocytes. Biomedical chromatography : BMC. 2021 Sep; 35(9):e5138. doi: 10.1002/bmc.5138. [PMID: 33830523]
  • Wenzhe Yu, Lida Fan, Mingfu Wang, Bin Cao, Xiaoqian Hu. Pterostilbene Improves Insulin Resistance Caused by Advanced Glycation End Products (AGEs) in Hepatocytes and Mice. Molecular nutrition & food research. 2021 08; 65(15):e2100321. doi: 10.1002/mnfr.202100321. [PMID: 34085383]
  • Bram M Ter Ellen, Nilima Dinesh Kumar, Ellen M Bouma, Berit Troost, Denise P I van de Pol, Heidi H van der Ende-Metselaar, Leonie Apperloo, Djoke van Gosliga, Maarten van den Berge, Martijn C Nawijn, Peter H J van der Voort, Jill Moser, Izabela A Rodenhuis-Zybert, Jolanda M Smit. Resveratrol and Pterostilbene Inhibit SARS-CoV-2 Replication in Air-Liquid Interface Cultured Human Primary Bronchial Epithelial Cells. Viruses. 2021 07; 13(7):. doi: 10.3390/v13071335. [PMID: 34372541]
  • Dan Tang, Wei Xiao, Wen-Ting Gu, Zhi-Tong Zhang, Shu-Hong Xu, Zhi-Quan Chen, You-Hua Xu, Lu-Yong Zhang, Shu-Mei Wang, Hong Nie. Pterostilbene prevents methylglyoxal-induced cytotoxicity in endothelial cells by regulating glyoxalase, oxidative stress and apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2021 Jul; 153(?):112244. doi: 10.1016/j.fct.2021.112244. [PMID: 33930484]
  • Mina T Kelleni. Resveratrol-zinc nanoparticles or pterostilbene-zinc: Potential COVID-19 mono and adjuvant therapy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Jul; 139(?):111626. doi: 10.1016/j.biopha.2021.111626. [PMID: 33894625]
  • Ping-Yun Fan-Jiang, Pei-Sheng Lee, Kalyanam Nagabhushanam, Chi-Tang Ho, Min-Hsiung Pan. Pterostilbene Attenuates High-Fat Diet and Dextran Sulfate Sodium-Induced Colitis via Suppressing Inflammation and Intestinal Fibrosis in Mice. Journal of agricultural and food chemistry. 2021 Jun; 69(25):7093-7103. doi: 10.1021/acs.jafc.1c02783. [PMID: 34152136]
  • Xi Zhao, Anhua Shi, Qiong Ma, Xueyan Yan, Ligong Bian, Pengyue Zhang, Junzi Wu. Nanoparticles prepared from pterostilbene reduce blood glucose and improve diabetes complications. Journal of nanobiotechnology. 2021 Jun; 19(1):191. doi: 10.1186/s12951-021-00928-y. [PMID: 34176494]
  • Onkar Bedi, Niharika Srivastava, Davinder Parsad, Pawan Krishan. Fatty acid synthase inhibition ameliorates diabetes induced liver injury in rodent experimental model. European journal of pharmacology. 2021 Jun; 901(?):174078. doi: 10.1016/j.ejphar.2021.174078. [PMID: 33839087]
  • Yuan Zou, Xiangtao Wang, Dongdong Bi, Jingxin Fu, Jianwei Han, Yifei Guo, Li Feng, Meihua Han. Pterostilbene nanoparticles with small particle size show excellent anti-breast cancer activityin vitroandin vivo. Nanotechnology. 2021 May; 32(32):. doi: 10.1088/1361-6528/abfdec. [PMID: 33946061]
  • S Gómez-Zorita, I Milton-Laskibar, M T Macarulla, L Biasutto, A Fernández-Quintela, J Miranda, A Lasa, N Segues, L Bujanda, M P Portillo. Pterostilbene modifies triglyceride metabolism in hepatic steatosis induced by high-fat high-fructose feeding: a comparison with its analog resveratrol. Food & function. 2021 Apr; 12(7):3266-3279. doi: 10.1039/d0fo03320k. [PMID: 33877249]
  • Juliana Maria Bitencourt de Morais, Ellen Mayara Souza Cruz, Carlos Vinícius Dalto da Rosa, Roberta Carvalho Cesário, Jurandir Fernando Comar, Carolina Campos Lima Moreira, Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva. Pterostilbene influences glycemia and lipidemia and enhances antioxidant status in the liver of rats that consumed sucrose solution. Life sciences. 2021 Mar; 269(?):119048. doi: 10.1016/j.lfs.2021.119048. [PMID: 33453246]
  • Ankur Kumar Tanwar, Neha Dhiman, Amit Kumar, Vikas Jaitak. Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. European journal of medicinal chemistry. 2021 Mar; 213(?):113037. doi: 10.1016/j.ejmech.2020.113037. [PMID: 33257172]
  • Byoungjin Park, Yong-Jae Lee. Pterostilbene Improves Stress-Related Behaviors and Partially Reverses Underlying Neuroinflammatory and Hormonal Changes in Stress-Challenged Mice. Journal of medicinal food. 2021 Mar; 24(3):299-309. doi: 10.1089/jmf.2020.4766. [PMID: 33739881]
  • Hao Zhang, Yanan Chen, Yueping Chen, Shuli Ji, Peilu Jia, Jianxiong Xu, Yue Li, Tian Wang. Pterostilbene attenuates liver injury and oxidative stress in intrauterine growth-retarded weanling piglets. Nutrition (Burbank, Los Angeles County, Calif.). 2021 01; 81(?):110940. doi: 10.1016/j.nut.2020.110940. [PMID: 32755743]
  • Saioa Gómez-Zorita, Iñaki Milton-Laskíbar, Leixuri Aguirre, Alfredo Fernández-Quintela, Jianbo Xiao, María P Portillo. Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids. Current medicinal chemistry. 2021; 28(2):238-252. doi: 10.2174/0929867326666191029112626. [PMID: 31663469]
  • Ivana Spevakova, Maria-Luisa Fernandez-Cruz, Katarina Tokarova, Hana Greifova, Marcela Capcarova. The protective effect of stilbenes resveratrol and pterostilbene individually and combined with mycotoxin citrinin in human adenocarcinoma HT-29 cell line in vitro. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2021; 56(1):75-88. doi: 10.1080/10934529.2020.1839279. [PMID: 33112704]
  • Hussam I Kutbi, Ahmed K Kammoun, Dalia Farag El-Telbany. Amelioration of Pterostilbene Antiproliferative, Proapoptotic, and Oxidant Potentials in Human Breast Cancer MCF7 Cells Using Zein Nanocomposites. International journal of nanomedicine. 2021; 16(?):3059-3071. doi: 10.2147/ijn.s303975. [PMID: 33953555]
  • Martina La Spina, Michele Azzolini, Andrea Salmaso, Sofia Parrasia, Eva Galletta, Marco Schiavone, Martina Chrisam, Andrea Mattarei, Giulietta Di Benedetto, Andrea Ballabio, Natascia Tiso, Mario Zoratti, Lucia Biasutto. Multiple Mechanisms Converging on Transcription Factor EB Activation by the Natural Phenol Pterostilbene. Oxidative medicine and cellular longevity. 2021; 2021(?):7658501. doi: 10.1155/2021/7658501. [PMID: 34992716]
  • Shiori Mori, Shingo Kishi, Kanya Honoki, Rina Fujiwara-Tani, Takuma Moriguchi, Takamitsu Sasaki, Kiyomu Fujii, Shinji Tsukamoto, Hiromasa Fujii, Akira Kido, Yasuhito Tanaka, Yi Luo, Hiroki Kuniyasu. Anti-Stem Cell Property of Pterostilbene in Gastrointestinal Cancer Cells. International journal of molecular sciences. 2020 Dec; 21(24):. doi: 10.3390/ijms21249347. [PMID: 33302440]
  • Jenifer Trepiana, Stéphanie Krisa, María Puy Portillo. Activity of Pterostilbene Metabolites against Liver Steatosis in Cultured Hepatocytes. Molecules (Basel, Switzerland). 2020 Nov; 25(22):. doi: 10.3390/molecules25225444. [PMID: 33233676]
  • Wei-Sheng Lin, Jane Valorie Leland, Chi-Tang Ho, Min-Hsiung Pan. Occurrence, Bioavailability, Anti-inflammatory, and Anticancer Effects of Pterostilbene. Journal of agricultural and food chemistry. 2020 Nov; 68(46):12788-12799. doi: 10.1021/acs.jafc.9b07860. [PMID: 32064876]
  • Hyunsook Kim, Kun-Ho Seo, Wallace Yokoyama. Chemistry of Pterostilbene and Its Metabolic Effects. Journal of agricultural and food chemistry. 2020 Nov; 68(46):12836-12841. doi: 10.1021/acs.jafc.0c00070. [PMID: 32125846]
  • Zhi Xu. 1,2,3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). European journal of medicinal chemistry. 2020 Nov; 206(?):112686. doi: 10.1016/j.ejmech.2020.112686. [PMID: 32795773]
  • Yeju Liu, Yuyang You, Juan Lu, Xi Chen, Zhihong Yang. Recent Advances in Synthesis, Bioactivity, and Pharmacokinetics of Pterostilbene, an Important Analog of Resveratrol. Molecules (Basel, Switzerland). 2020 Nov; 25(21):. doi: 10.3390/molecules25215166. [PMID: 33171952]
  • Onkar Bedi, Savera Aggarwal, Nirupma Trehanpati, Gayatri Ramakrishna, Ajmer Singh Grewal, Pawan Krishan. In vitro targeted screening and molecular docking of stilbene, quinones, and flavonoid on 3T3-L1 pre-adipocytes for anti-adipogenic actions. Naunyn-Schmiedeberg's archives of pharmacology. 2020 11; 393(11):2093-2106. doi: 10.1007/s00210-020-01919-w. [PMID: 32588069]
  • Froylan Sosa, Salvador Romo, Michael E Kjelland, Horacio Álvarez-Gallardo, Sandra Pérez-Reynozo, David Urbán-Duarte, Jose Fernando De La Torre-Sánchez. Effect of pterostilbene on development, equatorial lipid accumulation and reactive oxygen species production of in vitro-produced bovine embryos. Reproduction in domestic animals = Zuchthygiene. 2020 Nov; 55(11):1490-1500. doi: 10.1111/rda.13798. [PMID: 32767686]
  • Tingting Zhao, Chun Wang, Xinying Huo, Ming-Liang He, Jinfei Chen. Pterostilbene enhances sorafenib's anticancer effects on gastric adenocarcinoma. Journal of cellular and molecular medicine. 2020 11; 24(21):12525-12536. doi: 10.1111/jcmm.15795. [PMID: 33047871]
  • Hao Zhang, Yanan Chen, Yue Li, Peilu Jia, Shuli Ji, Yueping Chen, Tian Wang. Protective effects of pterostilbene against hepatic damage, redox imbalance, mitochondrial dysfunction, and endoplasmic reticulum stress in weanling piglets. Journal of animal science. 2020 Oct; 98(10):. doi: 10.1093/jas/skaa328. [PMID: 33027517]
  • Erli Zhang, Jingbo Huang, Kun Wang, Qinlei Yu, Chao Zhu, Hua Ren. Pterostilbene Protects Against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Failure by Upregulating the Nrf2 Pathway and Inhibiting NF-κB, MAPK, and NLRP3 Inflammasome Activation. Journal of medicinal food. 2020 Sep; 23(9):952-960. doi: 10.1089/jmf.2019.4647. [PMID: 32701014]
  • Denise Lacerda, Patrick Türck, Cristina Campos-Carraro, Alexandre Hickmann, Vanessa Ortiz, Sara Bianchi, Adriane Belló-Klein, Alexandre Luz de Castro, Valquiria Linck Bassani, Alex Sander da Rosa Araujo. Pterostilbene improves cardiac function in a rat model of right heart failure through modulation of calcium handling proteins and oxidative stress. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2020 Sep; 45(9):987-995. doi: 10.1139/apnm-2019-0864. [PMID: 32191845]
  • Davide Righi, Robin Huber, Alexey Koval, Laurence Marcourt, Sylvain Schnee, Anaïs Le Floch, Verena Ducret, Remo Perozzo, Concetta C de Ruvo, Nicole Lecoultre, Emilie Michellod, Samad N Ebrahimi, Elisabeth Rivara-Minten, Vladimir L Katanaev, Karl Perron, Jean-Luc Wolfender, Katia Gindro, Emerson F Queiroz. Generation of Stilbene Antimicrobials against Multiresistant Strains of Staphylococcus aureus through Biotransformation by the Enzymatic Secretome of Botrytis cinerea. Journal of natural products. 2020 08; 83(8):2347-2356. doi: 10.1021/acs.jnatprod.0c00071. [PMID: 32705864]
  • Petra Simic, Xavier Fernando Vela Parada, Samir M Parikh, Ryan Dellinger, Leonard P Guarente, Eugene P Rhee. Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI. BMC nephrology. 2020 08; 21(1):342. doi: 10.1186/s12882-020-02006-1. [PMID: 32791973]
  • E Vaňková, M Paldrychová, P Kašparová, K Lokočová, Z Kodeš, O Maťátková, I Kolouchová, J Masák. Natural antioxidant pterostilbene as an effective antibiofilm agent, particularly for gram-positive cocci. World journal of microbiology & biotechnology. 2020 Jul; 36(7):101. doi: 10.1007/s11274-020-02876-5. [PMID: 32613312]
  • Yanan Chen, Yueping Chen, Hao Zhang, Tian Wang. Pterostilbene as a protective antioxidant attenuates diquat-induced liver injury and oxidative stress in 21-day-old broiler chickens. Poultry science. 2020 Jun; 99(6):3158-3167. doi: 10.1016/j.psj.2020.01.021. [PMID: 32475452]
  • Hao Zhang, Yanan Chen, Yueping Chen, Peilu Jia, Shuli Ji, Jianxiong Xu, Yue Li, Tian Wang. Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat. Food & function. 2020 May; 11(5):4202-4215. doi: 10.1039/d0fo00732c. [PMID: 32352466]
  • Liang Wang, Hui Zhao, Liwen Wang, Yongqing Tao, Gang Du, Wenqiang Guan, Jianfu Liu, Charles Brennan, Chi-Tang Ho, Shiming Li. Effects of Selected Resveratrol Analogues on Activation and Polarization of Lipopolysaccharide-Stimulated BV-2 Microglial Cells. Journal of agricultural and food chemistry. 2020 Mar; 68(12):3750-3757. doi: 10.1021/acs.jafc.0c00498. [PMID: 32125844]
  • Wen-Yuan Wu, Xiao-Qin Ding, Ting-Ting Gu, Wen-Jie Guo, Rui-Qing Jiao, Lin Song, Yang Sun, Ying Pan, Ling-Dong Kong. Pterostilbene Improves Hepatic Lipid Accumulation via the MiR-34a/Sirt1/SREBP-1 Pathway in Fructose-Fed Rats. Journal of agricultural and food chemistry. 2020 Feb; 68(5):1436-1446. doi: 10.1021/acs.jafc.9b04259. [PMID: 31927917]
  • Hee Jeong Shin, Jang Mi Han, Ye Seul Choi, Hye Jin Jung. Pterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol. Molecules (Basel, Switzerland). 2020 Jan; 25(1):. doi: 10.3390/molecules25010228. [PMID: 31935877]
  • Yanhuan Feng, Fan Guo, Hongxia Mai, Jing Liu, Zijing Xia, Guonian Zhu, Jinhang Zhang, Liang Ma, Ping Fu. Pterostilbene, a Bioactive Component of Blueberries, Alleviates Renal Interstitial Fibrosis by Inhibiting Macrophage-Myofibroblast Transition. The American journal of Chinese medicine. 2020; 48(7):1715-1729. doi: 10.1142/s0192415x20500858. [PMID: 33148003]
  • Qiang Zhu, Tao Tang, Haixiao Liu, Yinxue Sun, Xiaogang Wang, Qiang Liu, Long Yang, Zhijie Lei, Zhao Huang, Zhao Chen, Qiang Lei, Mingyang Song, Bodong Wang. Pterostilbene Attenuates Cocultured BV-2 Microglial Inflammation-Mediated SH-SY5Y Neuronal Oxidative Injury via SIRT-1 Signalling. Oxidative medicine and cellular longevity. 2020; 2020(?):3986348. doi: 10.1155/2020/3986348. [PMID: 32831997]
  • Hao Zhang, Yanan Chen, Yueping Chen, Yue Li, Peilu Jia, Shuli Ji, Yanmin Zhou, Tian Wang. Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide. Journal of animal science. 2020 Jan; 98(1):. doi: 10.1093/jas/skz373. [PMID: 31822918]
  • Sibel Özdaş, Bora Taştekin, Seren G Gürgen, Talih Özdaş, Aykut Pelit, Sanem O Erkan, Birgül Tuhanioğlu, Birgül Gülnar, Orhan Görgülü. Pterostilbene protects cochlea from ototoxicity in streptozotocin-induced diabetic rats by inhibiting apoptosis. PloS one. 2020; 15(7):e0228429. doi: 10.1371/journal.pone.0228429. [PMID: 32722679]
  • Iván Millán, María Del Carmen Desco, Isabel Torres-Cuevas, Salvador Pérez, Inés Pulido, Salvador Mena-Mollá, Jorge Mataix, Miguel Asensi, Ángel Luis Ortega. Pterostilbene Prevents Early Diabetic Retinopathy Alterations in a Rabbit Experimental Model. Nutrients. 2019 Dec; 12(1):. doi: 10.3390/nu12010082. [PMID: 31892189]
  • Wei Wang, Ya-Ru Wang, Jing Chen, Ya-Jun Chen, Zhao-Xia Wang, Ming Geng, De-Cong Xu, Zi-Ying Wang, Jin-Hua Li, Zhong-Dong Xu, Li-Long Pan, Jia Sun. Pterostilbene Attenuates Experimental Atherosclerosis through Restoring Catalase-Mediated Redox Balance in Vascular Smooth Muscle Cells. Journal of agricultural and food chemistry. 2019 Nov; 67(46):12752-12760. doi: 10.1021/acs.jafc.9b05373. [PMID: 31642668]
  • Xueyan Ren, Xue Zhang, Xin Zhai, Rongrong Deng, Jiahui Meng, Xingyan Li, Qingjun Kong. Regulation of resveratrol O-methyltransferase gene in pterostilbene defensing the sour rot of wine grape. Journal of food biochemistry. 2019 11; 43(11):e13016. doi: 10.1111/jfbc.13016. [PMID: 31452220]
  • Dorota Nieoczym, Katarzyna Socała, Piotr Jedziniak, Elżbieta Wyska, Piotr Wlaź. Effect of Pterostilbene, a Natural Analog of Resveratrol, on the Activity of some Antiepileptic Drugs in the Acute Seizure Tests in Mice. Neurotoxicity research. 2019 Nov; 36(4):859-869. doi: 10.1007/s12640-019-00021-1. [PMID: 30877660]
  • Qianyuan Liu, Jingjing Chen, Yang Qin, Bo Jiang, Tao Zhang. Encapsulation of pterostilbene in nanoemulsions: influence of lipid composition on physical stability, in vitro digestion, bioaccessibility, and Caco-2 cell monolayer permeability. Food & function. 2019 Oct; 10(10):6604-6614. doi: 10.1039/c9fo01260e. [PMID: 31552977]
  • Yen-Chun Koh, Shiming Li, Pei-Yu Chen, Jia-Ching Wu, Nagabhushanam Kalyanam, Chi-Tang Ho, Min-Hsiung Pan. Prevention of Vascular Inflammation by Pterostilbene via Trimethylamine-N-Oxide Reduction and Mechanism of Microbiota Regulation. Molecular nutrition & food research. 2019 10; 63(20):e1900514. doi: 10.1002/mnfr.201900514. [PMID: 31368236]
  • Hualei Sun, Xinxin Liu, Shao Rong Long, Teng Wang, Huina Ge, Yan Wang, Songcheng Yu, Yuan Xue, Yujing Zhang, Xing Li, Wenjie Li. Antidiabetic effects of pterostilbene through PI3K/Akt signal pathway in high fat diet and STZ-induced diabetic rats. European journal of pharmacology. 2019 Sep; 859(?):172526. doi: 10.1016/j.ejphar.2019.172526. [PMID: 31283935]
  • Mina Nagumo, Masayuki Ninomiya, Natsuko Oshima, Tomohiro Itoh, Kaori Tanaka, Atsuyoshi Nishina, Mamoru Koketsu. Comparative analysis of stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors with neuroprotective and anti-inflammatory activities. Bioorganic & medicinal chemistry letters. 2019 09; 29(17):2475-2479. doi: 10.1016/j.bmcl.2019.07.026. [PMID: 31350127]
  • Sajad Ahmad Malik, Jhankar D Acharya, Neelay K Mehendale, Siddhesh S Kamat, Saroj S Ghaskadbi. Pterostilbene reverses palmitic acid mediated insulin resistance in HepG2 cells by reducing oxidative stress and triglyceride accumulation. Free radical research. 2019 Jul; 53(7):815-827. doi: 10.1080/10715762.2019.1635252. [PMID: 31223033]
  • Annick D van den Brand, Judith Villevoye, Sandra M Nijmeijer, Martin van den Berg, Majorie B M van Duursen. Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines. Toxicology. 2019 06; 422(?):35-43. doi: 10.1016/j.tox.2019.04.009. [PMID: 31004704]
  • Giovanna Simonetti, Cleofe Palocci, Alessio Valletta, Olga Kolesova, Laura Chronopoulou, Livia Donati, Antonio Di Nitto, Elisa Brasili, Pierpaolo Tomai, Alessandra Gentili, Gabriella Pasqua. Anti-Candida Biofilm Activity of Pterostilbene or Crude Extract from Non-Fermented Grape Pomace Entrapped in Biopolymeric Nanoparticles. Molecules (Basel, Switzerland). 2019 May; 24(11):. doi: 10.3390/molecules24112070. [PMID: 31151290]
  • Takao Koeduka, Miki Hatada, Hideyuki Suzuki, Shiro Suzuki, Kenji Matsui. Molecular cloning and functional characterization of an O-methyltransferase catalyzing 4'-O-methylation of resveratrol in Acorus calamus. Journal of bioscience and bioengineering. 2019 May; 127(5):539-543. doi: 10.1016/j.jbiosc.2018.10.011. [PMID: 30471982]
  • Leixuri Aguirre, Sara Palacios-Ortega, Alfredo Fernández-Quintela, Elizabeth Hijona, Luis Bujanda, María P Portillo. Pterostilbene Reduces Liver Steatosis and Modifies Hepatic Fatty Acid Profile in Obese Rats. Nutrients. 2019 04; 11(5):. doi: 10.3390/nu11050961. [PMID: 31035507]
  • Liang Yang, Yuanyuan Ran, Zhenzhen Quan, Ran Wang, Qinghu Yang, Qiutian Jia, Heao Zhang, Yanhui Li, Yiheng Peng, JianHua Liang, Hui Wang, Hiroshi Nakanishi, Yulin Deng, Hong Qing. Pterostilbene, an active component of the dragon's blood extract, acts as an antidepressant in adult rats. Psychopharmacology. 2019 Apr; 236(4):1323-1333. doi: 10.1007/s00213-018-5138-7. [PMID: 30607481]
  • Ri-Qing Yu, Zohre Kurt, Fei He, Jim C Spain. Biodegradation of the Allelopathic Chemical Pterostilbene by a Sphingobium sp. Strain from the Peanut Rhizosphere. Applied and environmental microbiology. 2019 03; 85(5):. doi: 10.1128/aem.02154-18. [PMID: 30578258]
  • Ting-Ting Gu, Tian-Yu Chen, Yan-Zi Yang, Xiao-Juan Zhao, Yang Sun, Tu-Shuai Li, Dong-Mei Zhang, Ling-Dong Kong. Pterostilbene alleviates fructose-induced renal fibrosis by suppressing TGF-β1/TGF-β type I receptor/Smads signaling in proximal tubular epithelial cells. European journal of pharmacology. 2019 Jan; 842(?):70-78. doi: 10.1016/j.ejphar.2018.10.008. [PMID: 30336139]
  • Neha Maharao, Jurgen Venitz, Phillip M Gerk. Use of generally recognized as safe or dietary compounds to inhibit buprenorphine metabolism: potential to improve buprenorphine oral bioavailability. Biopharmaceutics & drug disposition. 2019 Jan; 40(1):18-31. doi: 10.1002/bdd.2166. [PMID: 30520057]
  • Jing Pan, Min Shi, Lingzhi Li, Jing Liu, Fan Guo, Yanhuan Feng, Liang Ma, Ping Fu. Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019 Jan; 109(?):1802-1808. doi: 10.1016/j.biopha.2018.11.022. [PMID: 30551434]
  • Junfeng Zhou, Xinxin Ci, Xiaoyuan Ma, Qinlei Yu, Yan Cui, Yu Zhen, Shanshan Li. Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes. Frontiers in pharmacology. 2019; 10(?):497. doi: 10.3389/fphar.2019.00497. [PMID: 31139082]
  • Ying Zhang, Shaoyu Ren, Ying Ji, Yafeng Liang. Pterostilbene Ameliorates Nephropathy Injury in Streptozotocin-Induced Diabetic Rats. Pharmacology. 2019; 104(1-2):71-80. doi: 10.1159/000500293. [PMID: 31117104]