NCBI Taxonomy: 4783

Phytophthora (ncbi_taxid: 4783)

found 54 associated metabolites at genus taxonomy rank level.

Ancestor: Peronosporaceae

Child Taxonomies: Phytophthora idaei, Phytophthora capsici, Phytophthora cactorum, Phytophthora trifolii, Phytophthora pisi, Phytophthora rubi, Phytophthora alni, Phytophthora pini, Phytophthora cinnamomi, Phytophthora cryptogea, Phytophthora infestans, Phytophthora megakarya, Phytophthora palmivora, Phytophthora cambivora, Phytophthora citricola, Phytophthora fragariae, Phytophthora sojae, Phytophthora dauci, Phytophthora porri, Phytophthora oleae, Phytophthora lilii, Phytophthora megasperma, Phytophthora nicotianae, Phytophthora drechsleri, Phytophthora vignae, Phytophthora gemini, Phytophthora arecae, Phytophthora bishii, Phytophthora cajani, Phytophthora heveae, Phytophthora cyperi, Phytophthora caryae, Phytophthora x alni, Phytophthora andina, Phytophthora alpina, Phytophthora fallax, Phytophthora meadii, Phytophthora nagaii, Phytophthora cocois, Phytophthora tabaci, Phytophthora urerae, Phytophthora ilicis, Phytophthora mengei, Phytophthora medicaginis, Phytophthora litchii, Phytophthora gloveri, Phytophthora iranica, Phytophthora gibbosa, Phytophthora gregata, Phytophthora frigida, Phytophthora inflata, Phytophthora acerina, Phytophthora acaciae, Phytophthora procera, Phytophthora gallica, Phytophthora obscura, Phytophthora emzansi, Phytophthora stricta, Phytophthora melonis, Phytophthora betacei, Phytophthora moyootj, Phytophthora riparia, Phytophthora ramorum, Phytophthora formosa, Phytophthora citrophthora, Phytophthora pseudotsugae, Phytophthora syringae, Phytophthora capensis, Phytophthora cichorii, Phytophthora lactucae, Phytophthora arenaria, Phytophthora irrigata, Phytophthora amnicola, Phytophthora quininea, Phytophthora asparagi, Phytophthora botryosa, Phytophthora humicola, Phytophthora katsurae, Phytophthora phaseoli, Phytophthora primulae, Phytophthora sinensis, Phytophthora marrasii, Phytophthora morindae, Phytophthora nemorosa, Phytophthora elongata, Phytophthora mexicana, Phytophthora ipomoeae, Phytophthora boodjera, Phytophthora parsiana, Phytophthora tubulina, Phytophthora inundata, Phytophthora alticola, Phytophthora quercina, Phytophthora polonica, Phytophthora europaea, Phytophthora kelmanii, Phytophthora viadrina, Phytophthora captiosa, Phytophthora insolita, Phytophthora asiatica, Phytophthora flexuosa, Phytophthora borealis, Phytophthora foliorum, Phytophthora docyniae, Phytophthora chilensis, Phytophthora amaranthi, Phytophthora plurivora, Phytophthora x stagnum, Phytophthora oreophila, Phytophthora cacuminis, Phytophthora aleatoria, Phytophthora lateralis, Phytophthora kernoviae, Phytophthora mirabilis, Phytophthora litoralis, Phytophthora tenuimura, Phytophthora uniformis, Phytophthora lacustris, Phytophthora multivora, Phytophthora bilorbang, Phytophthora vulcanica, Phytophthora occultans, Phytophthora condilina, Phytophthora brassicae, Phytophthora uliginosa, Phytophthora pluvialis, Phytophthora pinifolia, Phytophthora afrocarpa, Phytophthora estuarina, Phytophthora hydrogena, Phytophthora attenuata, Phytophthora castaneae, Phytophthora formosana, Phytophthora intricata, Phytophthora pistaciae, Phytophthora podocarpi, Phytophthora fluvialis, Phytophthora tropicalis, Phytophthora virginiana, Phytophthora constricta, Phytophthora abietivora, Phytophthora colocasiae, Phytophthora celebensis, Phytophthora javanensis, Phytophthora panamensis, Phytophthora variabilis, Phytophthora subarctica, Phytophthora boehmeriae, Phytophthora aff. dauci, Phytophthora cf. heveae, Phytophthora parvispora, Phytophthora tyrrhenica, Phytophthora terminalis, Phytophthora cf. meadii, Phytophthora acaciivora, Phytophthora cooljarloo, Phytophthora kwongonina, Phytophthora sansomeana, Phytophthora hibernalis, Phytophthora crassamura, Phytophthora rosacearum, Phytophthora richardiae, Phytophthora cuyabensis, Phytophthora himalsilva, Phytophthora prodigiosa, Phytophthora aysenensis, Phytophthora thermophila, Phytophthora hedraiandra, Phytophthora ornamentata, Phytophthora austrocedri, Phytophthora tentaculata, Phytophthora ludoviciana, Phytophthora transitoria, Phytophthora tonkinensis, Phytophthora ukrainensis, Phytophthora personensis, Phytophthora quercetorum, Phytophthora pachypleura, Phytophthora cf. gregata, Phytophthora debattistii, Phytophthora versiformis, Phytophthora rhizophorae, Phytophthora macilentosa, Phytophthora aquimorbida, Phytophthora x cambivora, Phytophthora aff. meadii, Phytophthora mekongensis, Phytophthora cathayensis, Phytophthora heterospora, Phytophthora clandestina, Phytophthora multibullata, Phytophthora cf. arenaria, unclassified Phytophthora, Phytophthora scandinavica, Phytophthora cf. elongata, Phytophthora aff. capsici, Phytophthora cf. insolita, Phytophthora intercalaris, Phytophthora cf. mexicana, Phytophthora gondwanensis, Phytophthora cf. botryosa, Phytophthora castanetorum, Phytophthora cf. parsiana, Phytophthora himalayensis, Phytophthora gonapodyides, Phytophthora balyanboodja, Phytophthora psychrophila, Phytophthora agathidicida, Phytophthora mediterranea, Phytophthora x incrassata, Phytophthora chrysanthemi, Phytophthora cf. meadii 2, Phytophthora cf. meadii 1, Phytophthora cf. quininea, Phytophthora x pelgrandis, Phytophthora x serendipita, Phytophthora x vanyenensis, Phytophthora aff. arenaria, Phytophthora aff. humicola, Phytophthora theobromicola, Phytophthora pseudogallica, Phytophthora pseudogregata, Phytophthora siskiyouensis, Phytophthora aff. cichorii, Phytophthora niederhauseri, Phytophthora aff. parsiana, Phytophthora cf. castaneae, Phytophthora x multiformis, Phytophthora aff. asparagi, Phytophthora novae-guineae, Phytophthora aff. syringae, Phytophthora mississippiae, Phytophthora sulawesiensis, Phytophthora aff. botryosa, Phytophthora cf. citricola, Phytophthora aff. primulae, Phytophthora cf. palmivora, Phytophthora cf. gallica 2, Phytophthora cf. gallica 1, Phytophthora chlamydospora, Phytophthora multiglobulosa, Phytophthora fragariaefolia, Phytophthora erythroseptica, Phytophthora aff. citricola, Phytophthora pseudosyringae, Phytophthora pseudolactucae, Phytophthora cf. tropicalis, Phytophthora aff. cryptogea, Phytophthora aff. attenuata, Phytophthora aff. cambivora, Phytophthora cf. megasperma, Phytophthora pseudopolonica, Phytophthora cf. rosacearum, Phytophthora aff. infestans, Phytophthora chesapeakensis, Phytophthora cf. virginiana, Phytophthora pseudocryptogea, Phytophthora honggalleglyana, Phytophthora multivesiculata, Phytophthora pseudochilensis, Phytophthora aff. megasperma, Phytophthora aff. himalsilva, Phytophthora aff. boehmeriae, Phytophthora pseudokernoviae, Phytophthora x heterohybrida, Phytophthora aff. sansomeana, Phytophthora aff. rosacearum, Phytophthora cf. attenuata 2, Phytophthora cf. attenuata 1, Phytophthora cf. attenuata 3, Phytophthora aquae-cooljarloo, Phytophthora aff. citricola X, Phytophthora aff. hedraiandra, Phytophthora pseudorosacearum, Phytophthora cf. tropicalis 2, Phytophthora aff. citricola I, Phytophthora aff. citricola IV, Phytophthora aff. citricola IX, Phytophthora aff. citricola XI, Phytophthora aff. citrophthora, Phytophthora aff. pseudotsugae, Phytophthora cf. niederhauseri, Phytophthora aff. citricola II, Phytophthora aff. citricola III, Phytophthora insulinativitatica, Phytophthora macrochlamydospora, Phytophthora aff. citricola VII, Phytophthora aff. niederhauseri, Phytophthora aff. heterohybrida, Phytophthora cf. citricola/pini, Phytophthora aff. citricola VIII, Phytophthora cf. capsici FM-2011, Phytophthora aff. erythroseptica, Phytophthora cf. porri 1 FM-2011, Phytophthora cf. porri 2 FM-2011, Phytophthora cf. multivesiculata, Phytophthora cf. inundata D0S1P25, Phytophthora cf. heveae 2 FM-2011, Phytophthora cf. heveae 1 FM-2011, Phytophthora cf. meadii 1 FM-2011, Phytophthora aff. pseudocryptogea, Phytophthora cf. heveae 1 FM-2012, Phytophthora cf. heveae 2 FM-2012, Phytophthora aff. meadii AdP-2013, Phytophthora cf. cryptogea FM-2011, Phytophthora cf. citricola FM-2012, Phytophthora cf. citricola group E, Phytophthora aff. cactorum FNM-2014, Phytophthora cf. rosacearum PB-2013, Phytophthora cf. katsurae 1 FM-2012, Phytophthora cf. katsurae 2 FM-2012, Phytophthora cf. lacustris NJG-2014, Phytophthora cf. citricola 1 FM-2011, Phytophthora cf. cryptogea 2 FM-2011, Phytophthora cf. citricola 2 FM-2011, Phytophthora cf. cryptogea 1 FM-2012, Phytophthora cf. cryptogea 2 FM-2012, Phytophthora aff. meadii isolate Pr3, Phytophthora cf. cryptogea/drechsleri, Phytophthora aff. citricola 1 FM-2012, Phytophthora aff. citricola 2 FM-2012, Phytophthora cf. citrophthora 2 FM-2011, Phytophthora cf. citrophthora 2 FM-2012, Phytophthora cf. fluvialis hybrid DH117, Phytophthora cf. citrophthora 1a FM-2011, Phytophthora cf. citrophthora 1b FM-2011, Phytophthora cf. citrophthora 1b FM-2012, Phytophthora cf. thermophila hybrid DH106, Phytophthora cf. fluvialis hybrid VHS29992, Phytophthora amnicola x Phytophthora moyootj, Phytophthora humicola x Phytophthora inundata, Phytophthora moyootj x Phytophthora fluvialis, Phytophthora fluvialis x Phytophthora moyootj, Phytophthora moyootj x Phytophthora litoralis, Phytophthora lacustris x Phytophthora riparia, Phytophthora kelmanii x Phytophthora sansomeana, Phytophthora nicotianae x Phytophthora cactorum, Phytophthora moyootj x Phytophthora thermophila, Phytophthora thermophila x Phytophthora moyootj, Phytophthora amnicola x Phytophthora thermophila, Phytophthora cactorum x Phytophthora hedraiandra, Phytophthora thermophila x Phytophthora amnicola, Phytophthora medicaginis x Phytophthora cryptogea, Phytophthora chlamydospora x Phytophthora amnicola, Phytophthora amnicola x Phytophthora chlamydospora, Phytophthora chlamydospora x Phytophthora lacustris, Phytophthora cactorum x Phytophthora aff. hedraiandra, Phytophthora niederhauseri x Phytophthora aff. asparagi, Phytophthora occultans x Phytophthora aff. citrophthora

Resveratrol

(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol

C14H12O3 (228.0786)


Resveratrol is a stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4 by hydroxy groups. It has a role as a phytoalexin, an antioxidant, a glioma-associated oncogene inhibitor and a geroprotector. It is a stilbenol, a polyphenol and a member of resorcinols. Resveratrol (3,5,4-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet irradiation. In a 2004 issue of Science, Dr. Sinclair of Harvard University said resveratrol is not an easy molecule to protect from oxidation. It has been claimed that it is readily degraded by exposure to light, heat, and oxygen. However, studies find that Trans-resveratrol undergoes negligible oxidation in normal atmosphere at room temperature. Resveratrol is a plant polyphenol found in high concentrations in red grapes that has been proposed as a treatment for hyperlipidemia and to prevent fatty liver, diabetes, atherosclerosis and aging. Resveratrol use has not been associated with serum enzyme elevations or with clinically apparent liver injury. Resveratrol is a natural product found in Vitis rotundifolia, Vitis amurensis, and other organisms with data available. Resveratrol is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity); mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity); and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose- and time-dependent manner. (NCI05) Resveratrol is a metabolite found in or produced by Saccharomyces cerevisiae. A stilbene and non-flavonoid polyphenol produced by various plants including grapes and blueberries. It has anti-oxidant, anti-inflammatory, cardioprotective, anti-mutagenic, and anti-carcinogenic properties. It also inhibits platelet aggregation and the activity of several DNA HELICASES in vitro. Resveratrol is a polyphenolic phytoalexin. It is also classified as a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. The levels of resveratrol found in food vary greatly. Red wine contains between 0.2 and 5.8 mg/L depending on the grape variety, while white wine has much less. The reason for this difference is that red wine is fermented with grape skins, allowing the wine to absorb the resveratrol, whereas white wine is fermented after the skin has been removed. Resveratrol is also sold as a nutritional supplement. A number of beneficial health effects, such as anti-cancer, antiviral, neuroprotective, anti-aging, anti-inflammatory, and life-prolonging effects have been reported for resveratrol. The fact that resveratrol is found in the skin of red grapes and as a constituent of red wine may explain the "French paradox". This paradox is based on the observation that the incidence of coronary heart disease is relatively low in southern France despite high dietary intake of saturated fats. Resveratrol is thought to achieve these cardioprotective effects by a number of different routes: (1) inhibition of vascular cell adhesion molecule expression; (2) inhibition of vascular smooth muscle cell proliferation; (3) stimulation of endothelial nitric oxide synthase (eNOS) activity; (4) inhibition of platelet aggregation; and (5) inhibition of LDL peroxidation (PMID: 17875315, 14676260, 9678525). Resveratrol is a biomarker for the consumption of grapes and raisins. A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4 by hydroxy groups. COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors C1892 - Chemopreventive Agent > C54630 - Phase II Enzymes Inducer D020011 - Protective Agents > D000975 - Antioxidants C26170 - Protective Agent > C275 - Antioxidant D004791 - Enzyme Inhibitors Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9638; ORIGINAL_PRECURSOR_SCAN_NO 9635 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9646; ORIGINAL_PRECURSOR_SCAN_NO 9641 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4381; ORIGINAL_PRECURSOR_SCAN_NO 4379 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9607; ORIGINAL_PRECURSOR_SCAN_NO 9606 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9642; ORIGINAL_PRECURSOR_SCAN_NO 9638 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4383; ORIGINAL_PRECURSOR_SCAN_NO 4379 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4396; ORIGINAL_PRECURSOR_SCAN_NO 4394 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4381; ORIGINAL_PRECURSOR_SCAN_NO 4376 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9641; ORIGINAL_PRECURSOR_SCAN_NO 9638 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4375; ORIGINAL_PRECURSOR_SCAN_NO 4373 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9614; ORIGINAL_PRECURSOR_SCAN_NO 9611 CONFIDENCE standard compound; INTERNAL_ID 1110; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4398; ORIGINAL_PRECURSOR_SCAN_NO 4397 IPB_RECORD: 1781; CONFIDENCE confident structure IPB_RECORD: 321; CONFIDENCE confident structure Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].

   

epsilon-Viniferin

5-[6-hydroxy-2-(4-hydroxyphenyl)-4-[(Z)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

C28H22O6 (454.1416)


(7E,7R,8R)-epsilon-Viniferin is found in alcoholic beverages. (7E,7R,8R)-epsilon-Viniferin is isolated from leaves of wine grape (Vitis vinifera) infected with Botrytis cinere

   

Pterostilbene

Phenol, 4-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-

C16H16O3 (256.1099)


C26170 - Protective Agent > C275 - Antioxidant Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4]. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].

   

Lanosterol

(2S,5S,7R,11R,14R,15R)-2,6,6,11,15-pentamethyl-14-[(2R)-6-methylhept-5-en-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-1(10)-en-5-ol

C30H50O (426.3861)


Lanosterol, also known as lanosterin, belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. Thus, lanosterol is considered to be a sterol lipid molecule. Lanosterol is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Lanosterol is biochemically synthesized starting from acetyl-CoA by the HMG-CoA reductase pathway. The critical step is the enzymatic conversion of the acyclic terpene squalene to the polycylic lanosterol via 2,3-squalene oxide. Constituent of wool fat used e.g. as chewing-gum softenerand is) also from yeast COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Cyclodehydroisolubimin

5-methyl-4-(prop-1-en-2-yl)-6-oxaspiro[bicyclo[3.2.1]octane-8,1-cyclopentane]-3-one

C15H22O2 (234.162)


Cyclodehydroisolubimin is found in alcoholic beverages. Cyclodehydroisolubimin is a constituent of potatoes infected with Phytophthora infestans. Constituent of potatoes infected with Phytophthora infestans. Cyclodehydroisolubimin is found in alcoholic beverages and potato.

   

cis-Piceid

(2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(Z)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C20H22O8 (390.1315)


Constituent of the wine grape (Vitis vinifera). (Z)-Resveratrol 3-glucoside is found in fruits and common grape. cis-Piceid is found in common grape. cis-Piceid is a constituent of the wine grape (Vitis vinifera)

   

Viniferin

5-[6-hydroxy-2-(4-hydroxyphenyl)-4-[2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

C28H22O6 (454.1416)


   

delta-Viniferin

5-[(2S,3S)-5-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

C28H22O6 (454.1416)


Delta-viniferin, also known as resveratrol (E)-dehydrodimer or delta-viniferin, is a member of the class of compounds known as 2-arylbenzofuran flavonoids. 2-arylbenzofuran flavonoids are phenylpropanoids containing the 2-phenylbenzofuran moiety. Delta-viniferin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Delta-viniferin can be found in grape wine, which makes delta-viniferin a potential biomarker for the consumption of this food product. Delta-viniferin is a resveratrol dehydrodimer. It is an isomer of epsilon-viniferin. It can be isolated from stressed grapevine (Vitis vinifera) leaves. It is also found in plant cell cultures. or in wine. It can also be found in Rheum maximowiczii . Delta-viniferin, also known as resveratrol (E)-dehydrodimer or δ-viniferin, is a member of the class of compounds known as 2-arylbenzofuran flavonoids. 2-arylbenzofuran flavonoids are phenylpropanoids containing the 2-phenylbenzofuran moiety. Delta-viniferin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Delta-viniferin can be found in grape wine, which makes delta-viniferin a potential biomarker for the consumption of this food product. Delta-viniferin is a resveratrol dehydrodimer. It is an isomer of epsilon-viniferin. It can be isolated from stressed grapevine (Vitis vinifera) leaves. It is also found in plant cell cultures. or in wine. It can also be found in Rheum maximowiczii .

   

Pallidol

8,16-bis(4-hydroxyphenyl)tetracyclo[7.7.0.0²,⁷.0¹⁰,¹⁵]hexadeca-2,4,6,10(15),11,13-hexaene-4,6,12,14-tetrol

C28H22O6 (454.1416)


Pallidol is a member of the class of compounds known as indanes. Indanes are compounds containing an indane moiety, which consists of a cyclopentane fused to a benzene ring. Pallidol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Pallidol can be found in grape wine, which makes pallidol a potential biomarker for the consumption of this food product. Pallidol is a resveratrol dimer. It can be found in red wine, in Cissus pallida or in Parthenocissus laetevirens .

   

Pterostilbene

4-[(Z)-2-(3,5-dimethoxyphenyl)ethenyl]phenol

C16H16O3 (256.1099)


Pterostilbene is a member of the class of compounds known as stilbenes. Stilbenes are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. Pterostilbene is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Pterostilbene can be found in common grape and grape wine, which makes pterostilbene a potential biomarker for the consumption of these food products. Pterostilbene is a stilbenoid chemically related to resveratrol. In plants, it serves a defensive phytoalexin role . Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4]. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].

   

Resveratrol

3,4,5-Trihydroxystilbene

C14H12O3 (228.0786)


COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors C1892 - Chemopreventive Agent > C54630 - Phase II Enzymes Inducer D020011 - Protective Agents > D000975 - Antioxidants CONFIDENCE standard compound; EAWAG_UCHEM_ID 3241 C26170 - Protective Agent > C275 - Antioxidant D004791 - Enzyme Inhibitors Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].

   

Pterostilbene

trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene

C16H16O3 (256.1099)


Pterostilbene is a stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3 and 5. It has a role as an antioxidant, an antineoplastic agent, a neurotransmitter, a plant metabolite, an apoptosis inducer, a neuroprotective agent, an anti-inflammatory agent, a radical scavenger and a hypoglycemic agent. It is a stilbenol, a member of methoxybenzenes and a diether. It derives from a hydride of a trans-stilbene. Pterostilbene is a natural product found in Vitis rupestris, Pterocarpus marsupium, and other organisms with data available. Pterostilbene is a naturally-derived stilbenoid structurally related to resveratrol, with potential antioxidant, anti-inflammatory, pro-apoptotic, antineoplastic and cytoprotective activities. Upon administration, pterostilbene exerts its anti-oxidant activity by scavenging reactive oxygen species (ROS), thereby preventing oxidative stress and ROS-induced cell damage. It may also activate the nuclear factor erythroid 2-related factor 2 (Nrf2)-mediated pathway and increase the expression of various antioxidant enzymes, such as superoxide dismutase (SOD). In addition, pterostilbene is able to inhibit inflammation by reducing the expression of various inflammatory mediators, such as interleukin (IL) 1beta, tumor necrosis factor alpha (TNF-a), inducible nitric oxide synthase (iNOS), cyclooxygenases (COX), and nuclear factor kappa B (NF-kB). It also inhibits or prevents the activation of many signaling pathways involved in carcinogenesis, and increases expression of various tumor suppressor genes while decreasing expression of certain tumor promoting genes. It also directly induces apoptosis in tumor cells. See also: Pterocarpus marsupium wood (part of). A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3 and 5. C26170 - Protective Agent > C275 - Antioxidant Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4]. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].

   

miyabenol C

5-{6-hydroxy-4-[6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl}benzene-1,3-diol

C42H32O9 (680.2046)


Cis-miyabenol c is a member of the class of compounds known as 2-arylbenzofuran flavonoids. 2-arylbenzofuran flavonoids are phenylpropanoids containing the 2-phenylbenzofuran moiety. Cis-miyabenol c is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Cis-miyabenol c can be found in fennel and herbs and spices, which makes cis-miyabenol c a potential biomarker for the consumption of these food products.

   

pallidol

pallidol

C28H22O6 (454.1416)


A tetracyclic stilbenoid that is a homodimer obtained by cyclodimerisation of resveratrol.

   

Epsilon-Viniferin

1,3-BENZENEDIOL, 5-(2,3-DIHYDRO-6-HYDROXY-2-(4-HYDROXYPHENYL)-4-(2-(4-HYDROXYPHENYL)ETHENYL)-3-BENZOFURANYL)-, (2R-(2.ALPHA.,3.BETA.,4(E)))-

C28H22O6 (454.1416)


(-)-trans-epsilon-viniferin is a stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol. It has a role as a metabolite. It is a member of 1-benzofurans, a polyphenol and a stilbenoid. It is functionally related to a trans-resveratrol. It is an enantiomer of a (+)-trans-epsilon-viniferin. Epsilon-viniferin is a natural product found in Dipterocarpus grandiflorus, Dipterocarpus hasseltii, and other organisms with data available. A stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol.

   

Resveratrol

trans-resveratrol

C14H12O3 (228.0786)


Resveratrol, also known as 3,4,5-trihydroxystilbene or trans-resveratrol, is a member of the class of compounds known as stilbenes. Stilbenes are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. Thus, resveratrol is considered to be an aromatic polyketide lipid molecule. Resveratrol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Resveratrol is a bitter tasting compound and can be found in a number of food items such as broccoli, yellow wax bean, bilberry, and turnip, which makes resveratrol a potential biomarker for the consumption of these food products. Resveratrol can be found primarily in urine, as well as throughout most human tissues. Resveratrol exists in all eukaryotes, ranging from yeast to humans. Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or, when the plant is under attack by pathogens such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries . Resveratrol suppresses NF-kappaB (NF-kappaB) activation in HSV infected cells. Reports have indicated that HSV activates NF-kappaB during productive infection and this may be an essential aspect of its replication scheme [PMID: 9705914] (DrugBank). relative retention time with respect to 9-anthracene Carboxylic Acid is 0.738 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.740 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.730 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.733 Acquisition and generation of the data is financially supported by the Max-Planck-Society COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors C1892 - Chemopreventive Agent > C54630 - Phase II Enzymes Inducer D020011 - Protective Agents > D000975 - Antioxidants C26170 - Protective Agent > C275 - Antioxidant D004791 - Enzyme Inhibitors Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS IPB_RECORD: 2101; CONFIDENCE confident structure IPB_RECORD: 2901; CONFIDENCE confident structure Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7]. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].

   

piceid

(2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-hydroxyphenyl)vinyl]phenoxy]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol

C20H22O8 (390.1315)


Origin: Plant, Glucosides, Stilbenes (E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions[1]. (E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions[1]. (E/Z)-Polydatin ((E/Z)-Piceid) is a monocrystalline compound originally isolated from the root and rhizome of Polygonum cuspidatum. (E/Z)-Polydatin has anti-platelet aggregation, anti-oxidative action of low-density lipoprotein (LDL), cardioprotective activity, anti-inflammatory and immune-regulating functions[1]. Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses. Polydatin (Standard) is the analytical standard of Polydatin. This product is intended for research and analytical applications. Polydatin (Piceid), extracted from the roots of Reynoutria japonica, a widely used traditional Chinese remedies, possesses anti-inflammatory activity in several experimental models. Polydatin (Piceid) inhibits G6PD and induces oxidative and ER stresses.

   

cis-resveratrol

5[(1Z)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol

C14H12O3 (228.0786)


Annotation level-1 cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC50s of 12.2 μM and 37.6 μM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively[1].

   

Epsilon-viniferin

Epsilon-viniferin

C28H22O6 (454.1416)


Annotation level-1

   

cis-Piceid

(2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(Z)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5-triol

C20H22O8 (390.1315)


A stilbenoid that is cis-resveratrol substituted at position 3 by a beta-D-glucosyl residue.

   

Cyclodehydroisolubimin

5-methyl-3-(prop-1-en-2-yl)-6-oxaspiro[bicyclo[3.2.1]octane-8,1-cyclopentane]-3-one

C15H22O2 (234.162)


   

Lanosterin

Lanosta-8,24-dien-3beta-ol

C30H50O (426.3861)


A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Tocris-1418

5-[(1Z)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol

C14H12O3 (228.0786)


D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D020011 - Protective Agents > D000975 - Antioxidants D004791 - Enzyme Inhibitors cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC50s of 12.2 μM and 37.6 μM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively[1].

   

Lanster

(3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol

C30H50O (426.3861)


COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

delta-Viniferin

delta-Viniferin

C28H22O6 (454.1416)


   

(2R,3S)-cis-epsilon-viniferin

(2R,3S)-cis-epsilon-viniferin

C28H22O6 (454.1416)


A stilbenoid that is the (2R,3S)-cis-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of cis-resveratrol.

   

(2S,3R)-cis-epsilon-viniferin

(2S,3R)-cis-epsilon-viniferin

C28H22O6 (454.1416)


A stilbenoid that is the (2S,3R)-cis-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of cis-resveratrol.

   

4,14-bis(3,4-dihydroxyphenyl)-5,8-dihydroxy-3,11-dioxatricyclo[8.4.0.0²,⁷]tetradeca-1(10),2(7),8-trien-12-one

4,14-bis(3,4-dihydroxyphenyl)-5,8-dihydroxy-3,11-dioxatricyclo[8.4.0.0²,⁷]tetradeca-1(10),2(7),8-trien-12-one

C24H20O9 (452.1107)


   

(1r,4s,5s,11r,12r,15s,16s,22r)-4,15-bis(3,5-dihydroxyphenyl)-5,11,16,22-tetrakis(4-hydroxyphenyl)-6,17-dioxahexacyclo[10.10.0.0²,¹⁰.0³,⁷.0¹³,²¹.0¹⁴,¹⁸]docosa-2,7,9,13,18,20-hexaene-9,20-diol

(1r,4s,5s,11r,12r,15s,16s,22r)-4,15-bis(3,5-dihydroxyphenyl)-5,11,16,22-tetrakis(4-hydroxyphenyl)-6,17-dioxahexacyclo[10.10.0.0²,¹⁰.0³,⁷.0¹³,²¹.0¹⁴,¹⁸]docosa-2,7,9,13,18,20-hexaene-9,20-diol

C56H42O12 (906.2676)


   

3,8-dibromo-4-chloro-4,11,12,12-tetramethyl-7-oxatricyclo[6.3.1.0¹,⁶]dodec-9-en-11-ol

3,8-dibromo-4-chloro-4,11,12,12-tetramethyl-7-oxatricyclo[6.3.1.0¹,⁶]dodec-9-en-11-ol

C15H21Br2ClO2 (425.9597)


   

4,5'-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene

4,5'-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene

C15H21Br2ClO (409.9648)


   

5-{5-[2-(3,5-dihydroxyphenyl)ethenyl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl}benzene-1,3-diol

5-{5-[2-(3,5-dihydroxyphenyl)ethenyl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl}benzene-1,3-diol

C28H22O6 (454.1416)


   

(1s,6s,8s,12s)-10-bromo-4,11,11,12-tetramethyl-7-oxatricyclo[6.3.1.0¹,⁶]dodeca-3,9-dien-12-ol

(1s,6s,8s,12s)-10-bromo-4,11,11,12-tetramethyl-7-oxatricyclo[6.3.1.0¹,⁶]dodeca-3,9-dien-12-ol

C15H21BrO2 (312.0725)


   

3,11,19-tris(4-hydroxyphenyl)-4,12,20-trioxaheptacyclo[16.6.1.1²,⁵.1¹⁰,¹³.0²¹,²⁵.0⁹,²⁷.0¹⁷,²⁶]heptacosa-1(25),5(27),6,8,13(26),14,16,21,23-nonaene-7,15,23-triol

3,11,19-tris(4-hydroxyphenyl)-4,12,20-trioxaheptacyclo[16.6.1.1²,⁵.1¹⁰,¹³.0²¹,²⁵.0⁹,²⁷.0¹⁷,²⁶]heptacosa-1(25),5(27),6,8,13(26),14,16,21,23-nonaene-7,15,23-triol

C42H30O9 (678.189)


   

(4r,5s,14s)-4,14-bis(3,4-dihydroxyphenyl)-5,8-dihydroxy-3,11-dioxatricyclo[8.4.0.0²,⁷]tetradeca-1(10),2(7),8-trien-12-one

(4r,5s,14s)-4,14-bis(3,4-dihydroxyphenyl)-5,8-dihydroxy-3,11-dioxatricyclo[8.4.0.0²,⁷]tetradeca-1(10),2(7),8-trien-12-one

C24H20O9 (452.1107)


   

4,15-bis(3,5-dihydroxyphenyl)-5,11,16,22-tetrakis(4-hydroxyphenyl)-6,17-dioxahexacyclo[10.10.0.0²,¹⁰.0³,⁷.0¹³,²¹.0¹⁴,¹⁸]docosa-2,7,9,13,18,20-hexaene-9,20-diol

4,15-bis(3,5-dihydroxyphenyl)-5,11,16,22-tetrakis(4-hydroxyphenyl)-6,17-dioxahexacyclo[10.10.0.0²,¹⁰.0³,⁷.0¹³,²¹.0¹⁴,¹⁸]docosa-2,7,9,13,18,20-hexaene-9,20-diol

C56H42O12 (906.2676)


   

(1s,8r,9r,16s)-8,16-bis(4-hydroxyphenyl)-9-[(1s,8r,9r,16s)-4,6,12-trihydroxy-8,16-bis(4-hydroxyphenyl)-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10,12,14(17)-hexaen-9-yl]-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10(17),11,13-hexaene-4,6,12-triol

(1s,8r,9r,16s)-8,16-bis(4-hydroxyphenyl)-9-[(1s,8r,9r,16s)-4,6,12-trihydroxy-8,16-bis(4-hydroxyphenyl)-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10,12,14(17)-hexaen-9-yl]-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10(17),11,13-hexaene-4,6,12-triol

C56H42O12 (906.2676)


   

8,16-bis(4-hydroxyphenyl)-9-[4,6,12-trihydroxy-8,16-bis(4-hydroxyphenyl)-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10,12,14(17)-hexaen-9-yl]-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10(17),11,13-hexaene-4,6,12-triol

8,16-bis(4-hydroxyphenyl)-9-[4,6,12-trihydroxy-8,16-bis(4-hydroxyphenyl)-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10,12,14(17)-hexaen-9-yl]-15-oxatetracyclo[8.6.1.0²,⁷.0¹⁴,¹⁷]heptadeca-2,4,6,10(17),11,13-hexaene-4,6,12-triol

C56H42O12 (906.2676)


   

(2r,3r,10r,11r,18s,19s)-3,11,19-tris(4-hydroxyphenyl)-4,12,20-trioxaheptacyclo[16.6.1.1²,⁵.1¹⁰,¹³.0²¹,²⁵.0⁹,²⁷.0¹⁷,²⁶]heptacosa-1(25),5(27),6,8,13(26),14,16,21,23-nonaene-7,15,23-triol

(2r,3r,10r,11r,18s,19s)-3,11,19-tris(4-hydroxyphenyl)-4,12,20-trioxaheptacyclo[16.6.1.1²,⁵.1¹⁰,¹³.0²¹,²⁵.0⁹,²⁷.0¹⁷,²⁶]heptacosa-1(25),5(27),6,8,13(26),14,16,21,23-nonaene-7,15,23-triol

C42H30O9 (678.189)


   

5-{6-hydroxy-4-[6-hydroxy-2-(4-hydroxyphenyl)-4-[2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl}benzene-1,3-diol

5-{6-hydroxy-4-[6-hydroxy-2-(4-hydroxyphenyl)-4-[2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl}benzene-1,3-diol

C42H32O9 (680.2046)


   

3-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-amino-1,3-dihydroxybutylidene)amino]-1,3-dihydroxybutylidene}amino)-1-hydroxy-3-sulfanylpropylidene]amino}-1,3-dihydroxybutylidene)amino]-1,3-dihydroxybutylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene)amino]-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxypropylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino}-1-hydroxy-3-methylbutylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-1-hydroxy-3-methylbutylidene)amino]-1,3-dihydroxypropylidene}amino)-1-hydroxy-3-methylpentylidene]amino}-1-hydroxy-4-methylpentylidene)amino]-1,3-dihydroxypropylidene}amino)-3-({2-hydroxy-1-[(1-hydroxy-3-oxopropan-2-yl)-c-hydroxycarbonimidoyl]propyl}-c-hydroxycarbonimidoyl)propanoic acid

3-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-amino-1,3-dihydroxybutylidene)amino]-1,3-dihydroxybutylidene}amino)-1-hydroxy-3-sulfanylpropylidene]amino}-1,3-dihydroxybutylidene)amino]-1,3-dihydroxybutylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene)amino]-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxypropylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino}-1-hydroxy-3-methylbutylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-1-hydroxy-3-methylbutylidene)amino]-1,3-dihydroxypropylidene}amino)-1-hydroxy-3-methylpentylidene]amino}-1-hydroxy-4-methylpentylidene)amino]-1,3-dihydroxypropylidene}amino)-3-({2-hydroxy-1-[(1-hydroxy-3-oxopropan-2-yl)-c-hydroxycarbonimidoyl]propyl}-c-hydroxycarbonimidoyl)propanoic acid

C100H167N25O38S (2358.1624)


   

(1r,3r,4s,6s,8r,11r)-3,8-dibromo-4-chloro-4,11,12,12-tetramethyl-7-oxatricyclo[6.3.1.0¹,⁶]dodec-9-en-11-ol

(1r,3r,4s,6s,8r,11r)-3,8-dibromo-4-chloro-4,11,12,12-tetramethyl-7-oxatricyclo[6.3.1.0¹,⁶]dodec-9-en-11-ol

C15H21Br2ClO2 (425.9597)


   

(1s,2r,3's,4's,6r)-3',4-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene

(1s,2r,3's,4's,6r)-3',4-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-ene

C15H21Br2ClO (409.9648)


   

(1s,2r,2's,4's,5's,6r)-4,5'-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-en-2'-ol

(1s,2r,2's,4's,5's,6r)-4,5'-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-en-2'-ol

C15H21Br2ClO2 (425.9597)


   

5-[(2r,3r)-6-hydroxy-4-[(2s,3s)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(1z)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

5-[(2r,3r)-6-hydroxy-4-[(2s,3s)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(1z)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

C42H32O9 (680.2046)


   

5-[(2r,3s)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(1e)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

5-[(2r,3s)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(1e)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

C28H22O6 (454.1416)


   

3',5'-dimethoxy-4-stilbenol

3',5'-dimethoxy-4-stilbenol

C16H16O3 (256.1099)


   

4-({2-[(2-{[2-({2-[(2-{[2-({2-[(6-amino-2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-amino-1,3-dihydroxybutylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-3-sulfanylpropylidene]amino}-1,3-dihydroxybutylidene)amino]-1-hydroxypropylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene)amino]-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxypropylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino}-1-hydroxyhexylidene)amino]-1,3-dihydroxybutylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-1-hydroxy-3-methylbutylidene)amino]-1,3-dihydroxypropylidene}amino)-1-hydroxy-3-methylpentylidene]amino}-1-hydroxy-4-methylpentylidene)amino]-1,3-dihydroxypropylidene}amino)-4-({2-hydroxy-1-[(1-hydroxy-3-oxopropan-2-yl)-c-hydroxycarbonimidoyl]ethyl}-c-hydroxycarbonimidoyl)butanoic acid

4-({2-[(2-{[2-({2-[(2-{[2-({2-[(6-amino-2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-{[2-({2-[(2-amino-1,3-dihydroxybutylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-3-sulfanylpropylidene]amino}-1,3-dihydroxybutylidene)amino]-1-hydroxypropylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene)amino]-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene}amino)-1,3-dihydroxybutylidene]amino}-1-hydroxypropylidene)amino]-1-hydroxypropylidene}amino)-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino}-1-hydroxyhexylidene)amino]-1,3-dihydroxybutylidene}amino)-1-hydroxy-4-methylpentylidene]amino}-1-hydroxy-3-methylbutylidene)amino]-1,3-dihydroxypropylidene}amino)-1-hydroxy-3-methylpentylidene]amino}-1-hydroxy-4-methylpentylidene)amino]-1,3-dihydroxypropylidene}amino)-4-({2-hydroxy-1-[(1-hydroxy-3-oxopropan-2-yl)-c-hydroxycarbonimidoyl]ethyl}-c-hydroxycarbonimidoyl)butanoic acid

C100H168N26O37S (2357.1784)


   

(1s)-4,5'-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-en-2'-ol

(1s)-4,5'-dibromo-4'-chloro-1,3,3,4'-tetramethyl-7-oxaspiro[bicyclo[4.1.0]heptane-2,1'-cyclohexan]-4-en-2'-ol

C15H21Br2ClO2 (425.9597)


   

(3s,4s,6s,8s,9s)-4,8-dibromo-9-chloro-1,5,5,9-tetramethylspiro[5.5]undec-1-en-3-ol

(3s,4s,6s,8s,9s)-4,8-dibromo-9-chloro-1,5,5,9-tetramethylspiro[5.5]undec-1-en-3-ol

C15H23Br2ClO (411.9804)


   

tocilizumab

tocilizumab

C14H12O3 (228.0786)


   

(1s,8s,9s,16s)-8,16-bis(4-hydroxyphenyl)tetracyclo[7.7.0.0²,⁷.0¹⁰,¹⁵]hexadeca-2,4,6,10,12,14-hexaene-4,6,12,14-tetrol

(1s,8s,9s,16s)-8,16-bis(4-hydroxyphenyl)tetracyclo[7.7.0.0²,⁷.0¹⁰,¹⁵]hexadeca-2,4,6,10,12,14-hexaene-4,6,12,14-tetrol

C28H22O6 (454.1416)


   

(4r,6s,8s,9s)-4,8-dibromo-9-chloro-1,5,5,9-tetramethylspiro[5.5]undec-1-ene

(4r,6s,8s,9s)-4,8-dibromo-9-chloro-1,5,5,9-tetramethylspiro[5.5]undec-1-ene

C15H23Br2Cl (395.9855)


   

5-[(2r,3s)-6-hydroxy-2-(4-hydroxyphenyl)-4-[2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

5-[(2r,3s)-6-hydroxy-2-(4-hydroxyphenyl)-4-[2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol

C28H22O6 (454.1416)