(S)-p-Menth-1-en-4-ol (BioDeep_00000019609)

Main id: BioDeep_00000001095

 

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


(1S)-4-methyl-1-(propan-2-yl)cyclohex-3-en-1-ol

化学式: C10H18O (154.1357578)
中文名称: (+)-萜品-4-醇, 4-萜烯醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)[C@]1(O)CCC(C)=CC1
InChI: InChI=1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3

描述信息

(S)-p-Menth-1-en-4-ol occurs in many essential oils, e.g. lavende
Occurs in many essential oils, e.g. lavender
Terpinen-4-ol (4-Carvomenthenol), a naturally occurring monoterpene, is the main bioactive component of tea-tree oil. Terpinen-4-ol suppresses inflammatory mediator production by activated human monocytes. Terpinen-4-ol significantly enhances the effect of several chemotherapeutic and biological agents[1][2][3].
Terpinen-4-ol (4-Carvomenthenol), a naturally occurring monoterpene, is the main bioactive component of tea-tree oil. Terpinen-4-ol suppresses inflammatory mediator production by activated human monocytes. Terpinen-4-ol significantly enhances the effect of several chemotherapeutic and biological agents[1][2][3].

同义名列表

11 个代谢物同义名

(1S)-4-methyl-1-(propan-2-yl)cyclohex-3-en-1-ol; (1S)-1-isopropyl-4-methylcyclohex-3-en-1-ol; (S)-1-Isopropyl-4-methyl-3-cyclohexen-1-ol; (S)-(+)-P-Menth-1-en-4-ol; (S)-p-Menth-1-en-4-ol; 4-Terpineol, (+/-)-; S-4-Carvomenthenol; (+)-terpinen-4-ol; Terpinen-4-ol; S-Origanol; 4-Carvomenthenol



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

964 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jing Ren, Yi-Ming Wang, Shuai-Bing Zhang, Yang-Yong Lv, Huan-Chen Zhai, Shan Wei, Ping-An Ma, Yuan-Sen Hu. Terpinen-4-ol from tea tree oil prevents Aspergillus flavus growth in postharvest wheat grain. International journal of food microbiology. 2024 Jun; 418(?):110741. doi: 10.1016/j.ijfoodmicro.2024.110741. [PMID: 38733636]
  • Caroline Deweer, Karin Sahmer, Jérôme Muchembled. Anti-oomycete activities from essential oils and their major compounds on Phytophthora infestans. Environmental science and pollution research international. 2023 Oct; ?(?):. doi: 10.1007/s11356-023-29270-6. [PMID: 37779122]
  • Xinping Zhao, Hailong Wu, Shuaili Yue, Xin Chen, Yong Huang, Haiqun Cao, Min Liao. Role of CYP6MS subfamily enzymes in detoxification of Sitophilus zeamais after exposure to terpinen-4-ol and limonene. Pesticide biochemistry and physiology. 2023 Jun; 193(?):105426. doi: 10.1016/j.pestbp.2023.105426. [PMID: 37248004]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Anita Vidács, Erika Beáta Kerekes, Miklós Takó, Csaba Vágvölgyi, Judit Krisch. Eradication of multiple-species biofilms from food industrial and domestic surfaces using essential oils. Food science and technology international = Ciencia y tecnologia de los alimentos internacional. 2023 Mar; ?(?):10820132231165543. doi: 10.1177/10820132231165543. [PMID: 36959708]
  • Shanshan Gao, Xinlong Guo, Shumei Liu, Siying Li, Jiahao Zhang, Shuang Xue, Qingbo Tang, Kunpeng Zhang, Ruimin Li. Cytochrome P450 gene CYP6BQ8 mediates terpinen-4-ol susceptibility in the red flour beetle, Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae). Bulletin of entomological research. 2023 Jan; ?(?):1-11. doi: 10.1017/s0007485322000566. [PMID: 36636814]
  • Souad El Hafidi, Khadija Bakhy, Mohammed Ouhssine, Abderrahim Benzakour, Hamid Khamar, Joseph Casanova, Mathieu Paoli, Félix Tomi. Composition and Chemical Variability of the Essential Oil from Aerial Parts of Cladanthus scariosus, an Endemic Species to the Moroccan High Atlas. Chemistry & biodiversity. 2023 Jan; 20(1):e202201022. doi: 10.1002/cbdv.202201022. [PMID: 36520049]
  • Meilin Li, Shunlong Liu, Zhijuan Yin, Charlotte Bernigaud, Jacques Guillot, Fang Fang. Activity of terpenes derived from essential oils against Sarcoptes scabiei eggs. Parasites & vectors. 2021 Dec; 14(1):600. doi: 10.1186/s13071-021-05094-6. [PMID: 34886874]
  • Sahar Ghulam Mohyuddin, Aftab Qamar, Can-Ying Hu, Yun Li, Sheng-Wei Chen, Jia-Ying Wen, Ming-Long Bao, Xiang Hong Ju. Terpinen4-ol inhibits heat stress induced inflammation in colonic tissue by Activating Occludin, Claudin-2 and TLR4/NF-κB signaling pathway. International immunopharmacology. 2021 Oct; 99(?):107727. doi: 10.1016/j.intimp.2021.107727. [PMID: 34426115]
  • Zhenbiao Li, Yingying Wei, Zidan Cao, Shu Jiang, Yi Chen, Xingfeng Shao. The Jasmonic Acid Signaling Pathway is Associated with Terpinen-4-ol-Induced Disease Resistance against Botrytis cinerea in Strawberry Fruit. Journal of agricultural and food chemistry. 2021 Sep; 69(36):10678-10687. doi: 10.1021/acs.jafc.1c04608. [PMID: 34468130]
  • Yanyan Zhang, Li He, Mengxin Tu, Mei Huang, Yan Chen, Di Pan, Jianqing Peng, Xiangchun Shen. The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation. Pharmacological research. 2021 08; 170(?):105629. doi: 10.1016/j.phrs.2021.105629. [PMID: 34089864]
  • Tyler M Wilson, Ariel Poulson, Chris Packer, Richard E Carlson, R Michael Buch. Essential Oil Profile and Yield of Corolla, Calyx, Leaf, and Whole Flowering Top of Cultivated Lavandula angustifolia Mill. (Lamiaceae) from Utah. Molecules (Basel, Switzerland). 2021 Apr; 26(8):. doi: 10.3390/molecules26082343. [PMID: 33920647]
  • Anan Athipornchai, Rungnapha Kumpang, Suwanna Semsri. Potential Biological Activities of Clausena Essential Oils for the Treatment of Diabetes. Journal of oleo science. 2021; 70(11):1669-1676. doi: 10.5650/jos.ess19294. [PMID: 34732637]
  • Qian Xu, Luyun Zhang, Shuai Yu, Guangqing Xia, Junyi Zhu, Hao Zang. Chemical composition and biological activities of an essential oil from the aerial parts of Artemisia Gmelinii weber ex Stechm. Natural product research. 2021 Jan; 35(2):346-349. doi: 10.1080/14786419.2019.1627349. [PMID: 31177847]
  • Di Chen, Jingyi Wang, David A Sullivan, Wendy R Kam, Yang Liu. Effects of Terpinen-4-ol on Meibomian Gland Epithelial Cells In Vitro. Cornea. 2020 Dec; 39(12):1541-1546. doi: 10.1097/ico.0000000000002506. [PMID: 32947397]
  • Zhenbiao Li, Nan Wang, Yingying Wei, Xiurong Zou, Shu Jiang, Feng Xu, Hongfei Wang, Xingfeng Shao. Terpinen-4-ol Enhances Disease Resistance of Postharvest Strawberry Fruit More Effectively than Tea Tree Oil by Activating the Phenylpropanoid Metabolism Pathway. Journal of agricultural and food chemistry. 2020 Jun; 68(24):6739-6747. doi: 10.1021/acs.jafc.0c01840. [PMID: 32379969]
  • Min Liao, Su Shi, Hailong Wu, Qianqian Yang, Zeng Zhu, Jinjing Xiao, Yong Huang, Haiqun Cao. Effects of terpinen-4-ol fumigation on protein levels of detoxification enzymes in Tribolium confusum. Archives of insect biochemistry and physiology. 2020 Apr; 103(4):e21653. doi: 10.1002/arch.21653. [PMID: 31859418]
  • Dlzar A Kheder, Omar A M Al-Habib, Gianluca Gilardoni, Giovanni Vidari. Components of Volatile Fractions from Eucalyptus camaldulensis Leaves from Iraqi-Kurdistan and Their Potent Spasmolytic Effects. Molecules (Basel, Switzerland). 2020 Feb; 25(4):. doi: 10.3390/molecules25040804. [PMID: 32069801]
  • Yong Huang, Min Liao, Qianqian Yang, Su Shi, Jinjing Xiao, Haiqun Cao. Knockdown of NADPH-cytochrome P450 reductase and CYP6MS1 increases the susceptibility of Sitophilus zeamais to terpinen-4-ol. Pesticide biochemistry and physiology. 2020 Jan; 162(?):15-22. doi: 10.1016/j.pestbp.2019.07.008. [PMID: 31836049]
  • J Tyler Ramsey, Yin Li, Yukitomo Arao, Ajanta Naidu, Laurel A Coons, Alejandro Diaz, Kenneth S Korach. Lavender Products Associated With Premature Thelarche and Prepubertal Gynecomastia: Case Reports and Endocrine-Disrupting Chemical Activities. The Journal of clinical endocrinology and metabolism. 2019 11; 104(11):5393-5405. doi: 10.1210/jc.2018-01880. [PMID: 31393563]
  • Yang Wang, Li-Ting Zhang, Yi-Xi Feng, Shan-Shan Guo, Xue Pang, Di Zhang, Zhu-Feng Geng, Shu-Shan Du. Insecticidal and repellent efficacy against stored-product insects of oxygenated monoterpenes and 2-dodecanone of the essential oil from Zanthoxylum planispinum var. dintanensis. Environmental science and pollution research international. 2019 Aug; 26(24):24988-24997. doi: 10.1007/s11356-019-05765-z. [PMID: 31240663]
  • Teresa Della Pepa, Hazem S Elshafie, Raffaele Capasso, Vincenzo De Feo, Ippolito Camele, Filomena Nazzaro, Maria Rosa Scognamiglio, Lucia Caputo. Antimicrobial and Phytotoxic Activity of Origanum heracleoticum and O. majorana Essential Oils Growing in Cilento (Southern Italy). Molecules (Basel, Switzerland). 2019 Jul; 24(14):. doi: 10.3390/molecules24142576. [PMID: 31315175]
  • Karolina Połeć, Aneta Wójcik, Michał Flasiński, Paweł Wydro, Marcin Broniatowski, Katarzyna Hąc-Wydro. The influence of terpinen-4-ol and eucalyptol - The essential oil components - on fungi and plant sterol monolayers. Biochimica et biophysica acta. Biomembranes. 2019 06; 1861(6):1093-1102. doi: 10.1016/j.bbamem.2019.03.015. [PMID: 30926362]
  • Asit Ray, Sudipta Jena, Basudeba Kar, Jeetendranath Patnaik, Pratap Chandra Panda, Sanghamitra Nayak. Chemical composition and antioxidant activities of essential oil of Hedychium greenii and Hedychium gracile from India. Natural product research. 2019 May; 33(10):1482-1485. doi: 10.1080/14786419.2017.1416384. [PMID: 29252004]
  • Yong Huang, Min Liao, Qianqian Yang, Jinjing Xiao, Zhaoyin Hu, Haiqun Cao. iTRAQ-based quantitative proteome revealed metabolic changes of Sitophilus zeamais in response to terpinen-4-ol fumigation. Pest management science. 2019 Feb; 75(2):444-451. doi: 10.1002/ps.5135. [PMID: 30039555]
  • Paola Brun, Giulia Bernabè, Raffaella Filippini, Anna Piovan. In Vitro Antimicrobial Activities of Commercially Available Tea Tree (Melaleuca alternifolia) Essential Oils. Current microbiology. 2019 Jan; 76(1):108-116. doi: 10.1007/s00284-018-1594-x. [PMID: 30421144]
  • Talha Ali Chohan, Tahir Ali Chohan, Lijun Zhou, Qianqian Yang, Liao Min, Haiqun Cao. Repellency, Toxicity, Gene Expression Profiling and In Silico Studies to Explore Insecticidal Potential of Melaleuca alternifolia Essential Oil against Myzus persicae. Toxins. 2018 Oct; 10(11):. doi: 10.3390/toxins10110425. [PMID: 30366370]
  • Emira Noumi, Abderrahmen Merghni, Mousa M Alreshidi, Ons Haddad, Gültekin Akmadar, Laura De Martino, Maha Mastouri, Ozgur Ceylan, Mejdi Snoussi, Abdulbasit Al-Sieni, Vincenzo De Feo. Chromobacterium violaceum and Pseudomonas aeruginosa PAO1: Models for Evaluating Anti-Quorum Sensing Activity of Melaleuca alternifolia Essential Oil and Its Main Component Terpinen-4-ol. Molecules (Basel, Switzerland). 2018 Oct; 23(10):. doi: 10.3390/molecules23102672. [PMID: 30336602]
  • Nelson Siu Kei Lam, Xin Xin Long, Robert C Griffin, Mu-Kai Chen, James Cg Doery. Can the tea tree oil (Australian native plant: Melaleuca alternifolia Cheel) be an alternative treatment for human demodicosis on skin?. Parasitology. 2018 10; 145(12):1510-1520. doi: 10.1017/s0031182018000495. [PMID: 29667560]
  • Noohi Nasim, Jay Krishna Behera, I Sriram Sandeep, V V RamaRao, Basudeba Kar, Antaryami Mishra, Sanghamitra Nayak, Sujata Mohanty. Phytochemical analysis of flower from Pandanus odorifer (Forssk.) Kuntze for industrial application. Natural product research. 2018 Oct; 32(20):2494-2497. doi: 10.1080/14786419.2017.1422184. [PMID: 29298498]
  • Yuetian Zhang, Ruizhang Feng, Lixia Li, Xun Zhou, Zhengwen Li, Renyong Jia, Xu Song, Yuanfeng Zou, Lizi Yin, Changliang He, Xiaoxia Liang, Wanhai Zhou, Qin Wei, Yonghua Du, Kuan Yan, Zili Wu, Zhongqiong Yin. The Antibacterial Mechanism of Terpinen-4-ol Against Streptococcus agalactiae. Current microbiology. 2018 Sep; 75(9):1214-1220. doi: 10.1007/s00284-018-1512-2. [PMID: 29804206]
  • Yong Huang, Min Liao, Qianqian Yang, Jinjing Xiao, Zhaoyin Hu, Lijun Zhou, Haiqun Cao. Transcriptome profiling reveals differential gene expression of detoxification enzymes in Sitophilus zeamais responding to terpinen-4-ol fumigation. Pesticide biochemistry and physiology. 2018 Jul; 149(?):44-53. doi: 10.1016/j.pestbp.2018.05.008. [PMID: 30033015]
  • Andreia R Bucci, Larissa Marcelino, Renata K Mendes, Augusto Etchegaray. The antimicrobial and antiadhesion activities of micellar solutions of surfactin, CTAB and CPCl with terpinen-4-ol: applications to control oral pathogens. World journal of microbiology & biotechnology. 2018 Jun; 34(6):86. doi: 10.1007/s11274-018-2472-1. [PMID: 29876752]
  • Wirginia Kukula-Koch, Wojciech Koch, Lidia Czernicka, Kazimierz Głowniak, Yoshinori Asakawa, Akemi Umeyama, Zbigniew Marzec, Takashi Kuzuhara. MAO-A Inhibitory Potential of Terpene Constituents from Ginger Rhizomes-A Bioactivity Guided Fractionation. Molecules (Basel, Switzerland). 2018 May; 23(6):. doi: 10.3390/molecules23061301. [PMID: 29844252]
  • Małgorzata Kucharska, Jadwiga A Szymańska, Wiktor Wesołowski, Elżbieta Bruchajzer, Barbara Frydrych. [Comparison of chemical composition of selected essential oils used in respiratory diseases]. Medycyna pracy. 2018 Mar; 69(2):167-178. doi: 10.13075/mp.5893.00673. [PMID: 29300393]
  • Rungarun Tisgratog, Chutipong Sukkanon, John P Grieco, Unchalee Sanguanpong, Kamlesh R Chauhan, Joel R Coats, Theeraphap Chareonviriyaphap. Evaluation of the Constituents of Vetiver Oil Against Anopheles minimus (Diptera: Culicidae), a Malaria Vector in Thailand. Journal of medical entomology. 2018 01; 55(1):193-199. doi: 10.1093/jme/tjx188. [PMID: 29029183]
  • Amanda Padovan, Andras Keszei, Yasmin Hassan, Sandra T Krause, Tobias G Köllner, Jörg Degenhardt, Jonathan Gershenzon, Carsten Külheim, William J Foley. Four terpene synthases contribute to the generation of chemotypes in tea tree (Melaleuca alternifolia). BMC plant biology. 2017 Oct; 17(1):160. doi: 10.1186/s12870-017-1107-2. [PMID: 28978322]
  • Antonio Nei Santana Gondim, Aline Lara, Artur Santos-Miranda, Danilo Roman-Campos, Sandra Lauton-Santos, José Evaldo Rodrigues Menezes-Filho, Carla Maria Lins de Vasconcelos, Eduardo Antonio Conde-Garcia, Silvia Guatimosim, Jader S Cruz. (-)-Terpinen-4-ol changes intracellular Ca2+ handling and induces pacing disturbance in rat hearts. European journal of pharmacology. 2017 Jul; 807(?):56-63. doi: 10.1016/j.ejphar.2017.04.022. [PMID: 28435092]
  • Katarzyna Hąc-Wydro, Michał Flasiński, Marcin Broniatowski, Monika Sołtys. Studies on the Behavior of Eucalyptol and Terpinen-4-ol-Natural Food Additives and Ecological Pesticides-in Model Lipid Membranes. Langmuir : the ACS journal of surfaces and colloids. 2017 07; 33(27):6916-6924. doi: 10.1021/acs.langmuir.7b00774. [PMID: 28654274]
  • Gabriel Garcia, Adrien Garcia, Marc Gibernau, Ange Bighelli, Félix Tomi. Chemical compositions of essential oils of five introduced conifers in Corsica. Natural product research. 2017 Jul; 31(14):1697-1703. doi: 10.1080/14786419.2017.1285299. [PMID: 28278672]
  • Fredrik Schubert, Katinka Pålsson, Ellen Santangelo, Anna-Karin Borg-Karlson. Sulfate turpentine: a resource of tick repellent compounds. Experimental & applied acarology. 2017 Jul; 72(3):291-302. doi: 10.1007/s10493-017-0145-7. [PMID: 28589297]
  • Aida Lahmar, Ahmed Bedoui, Imen Mokdad-Bzeouich, Zaineb Dhaouifi, Zahar Kalboussi, Imed Cheraif, Kamel Ghedira, Leila Chekir-Ghedira. Reversal of resistance in bacteria underlies synergistic effect of essential oils with conventional antibiotics. Microbial pathogenesis. 2017 May; 106(?):50-59. doi: 10.1016/j.micpath.2016.10.018. [PMID: 27815129]
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  • Katarzyna Hąc-Wydro, Karolina Szydło. The influence of environmentally friendly pesticide - Eucalyptol - alone and in combination with terpinen-4-ol - on model bacterial membranes. Colloids and surfaces. B, Biointerfaces. 2016 Oct; 146(?):918-23. doi: 10.1016/j.colsurfb.2016.07.044. [PMID: 27472454]
  • Alessandra Manzo, Loana Musso, Sara Panseri, Marcello Iriti, Sabrina Dallavalle, Enrico Catalano, Giorgio Scarì, Annamaria Giorgi. Screening of the chemical composition and bioactivity of Waldheimia glabra (Decne.) Regel essential oil. Journal of the science of food and agriculture. 2016 Jul; 96(9):3195-201. doi: 10.1002/jsfa.7499. [PMID: 26467601]
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  • Petar Knezevic, Verica Aleksic, Natasa Simin, Emilija Svircev, Aleksandra Petrovic, Neda Mimica-Dukic. Antimicrobial activity of Eucalyptus camaldulensis essential oils and their interactions with conventional antimicrobial agents against multi-drug resistant Acinetobacter baumannii. Journal of ethnopharmacology. 2016 Feb; 178(?):125-36. doi: 10.1016/j.jep.2015.12.008. [PMID: 26671210]
  • Marimuthu Govindarajan, Mohan Rajeswary, S L Hoti, Giovanni Benelli. Larvicidal potential of carvacrol and terpinen-4-ol from the essential oil of Origanum vulgare (Lamiaceae) against Anopheles stephensi, Anopheles subpictus, Culex quinquefasciatus and Culex tritaeniorhynchus (Diptera: Culicidae). Research in veterinary science. 2016 Feb; 104(?):77-82. doi: 10.1016/j.rvsc.2015.11.011. [PMID: 26850541]
  • Cheng-Fang Wang, Kai Yang, Chun-Xue You, Wen-Juan Zhang, Shan-Shan Guo, Zhu-Feng Geng, Shu-Shan Du, Yong-Yan Wang. Chemical Composition and Insecticidal Activity of Essential Oils from Zanthoxylum dissitum Leaves and Roots against Three Species of Storage Pests. Molecules (Basel, Switzerland). 2015 May; 20(5):7990-9. doi: 10.3390/molecules20057990. [PMID: 25946557]
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  • Wen-Juan Zhang, Kai Yang, Chun-Xue You, Ying Wang, Cheng-Fang Wang, Yan Wu, Zhu-Feng Geng, Yang Su, Shu-Shan Du, Zhi-Wei Deng. Bioactivity of essential oil from Artemisia stolonifera (Maxim.) Komar. and its main compounds against two stored-product insects. Journal of oleo science. 2015; 64(3):299-307. doi: 10.5650/jos.ess14187. [PMID: 25757434]
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  • D C Cabrera, G L S Gomes, A Flach, L A M A da Costa, G R Rosa, N F de Moura. Evaluation of climatic factors on the yield and chemical composition of the essential oil of Myrocarpus frondosus. Natural product research. 2015; 29(7):667-70. doi: 10.1080/14786419.2014.976642. [PMID: 25421822]
  • M N M Nogueira, S G Aquino, C Rossa Junior, D M P Spolidorio. Terpinen-4-ol and alpha-terpineol (tea tree oil components) inhibit the production of IL-1β, IL-6 and IL-10 on human macrophages. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2014 Sep; 63(9):769-78. doi: 10.1007/s00011-014-0749-x. [PMID: 24947163]
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