Nicotinic acid (BioDeep_00000000192)

 

Secondary id: BioDeep_00000400200, BioDeep_00000859641

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Chemicals and Drugs BioNovoGene_Lab2019


代谢物信息卡片


pyridine-3-carboxylic acid

化学式: C6H5NO2 (123.032)
中文名称: 烟酸
谱图信息: 最多检出来源 Homo sapiens(plant) 9.61%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Nicotinic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/nicotinic_acid (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000192). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=CN=C1)C(=O)O
InChI: InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

描述信息

Nicotinic acid is an odorless white crystalline powder with a feebly acid taste. pH (saturated aqueous solution) 2.7. pH (1.3\\\\\% solution) 3-3.5. (NTP, 1992)
Nicotinic acid is a pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. It has a role as an antidote, an antilipemic drug, a vasodilator agent, a metabolite, an EC 3.5.1.19 (nicotinamidase) inhibitor, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a plant metabolite. It is a vitamin B3, a pyridinemonocarboxylic acid and a pyridine alkaloid. It is a conjugate acid of a nicotinate.
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Nicotinic acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Niacin is a Nicotinic Acid.
Niacin, also known as nicotinic acid and vitamin B3, is a water soluble, essential B vitamin that, when given in high doses, is effective in lowering low density lipoprotein (LDL) cholesterol and raising high density lipoprotein (HDL) cholesterol, which makes this agent of unique value in the therapy of dyslipidemia. Niacin can cause mild-to-moderate serum aminotransferase elevations and high doses and certain formulations of niacin have been linked to clinically apparent, acute liver injury which can be severe as well as fatal.
Niacin is a water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C.
Nicotinic acid, also known as niacin or vitamin B3, is a water-soluble vitamin whose derivatives such as NADH, NAD, NAD+, and NADP play essential roles in energy metabolism in the living cell and DNA repair. The designation vitamin B3 also includes the amide form, nicotinamide or niacinamide. Severe lack of niacin causes the deficiency disease pellagra, whereas a mild deficiency slows down the metabolism decreasing cold tolerance. The recommended daily allowance of niacin is 2-12 mg a day for children, 14 mg a day for women, 16 mg a day for men, and 18 mg a day for pregnant or breast-feeding women. It is found in various animal and plant tissues and has pellagra-curative, vasodilating, and antilipemic properties. The liver can synthesize niacin from the essential amino acid tryptophan (see below), but the synthesis is extremely slow and requires vitamin B6; 60 mg of tryptophan are required to make one milligram of niacin. Bacteria in the gut may also perform the conversion but are inefficient.
A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
Nicotinic acid, also known as niacin or vitamin B3, is a water-soluble vitamin whose derivatives such as NADH, NAD, NAD+, and NADP play essential roles in energy metabolism in the living cell and DNA repair. The designation vitamin B3 also includes the amide form, nicotinamide or niacinamide. Severe lack of niacin causes the deficiency disease pellagra, whereas a mild deficiency slows down the metabolism decreasing cold tolerance. The recommended daily allowance of niacin is 2-12 mg a day for children, 14 mg a day for women, 16 mg a day for men, and 18 mg a day for pregnant or breast-feeding women. It is found in various animal and plant tissues and has pellagra-curative, vasodilating, and antilipemic properties. The liver can synthesize niacin from the essential amino acid tryptophan, but the synthesis is extremely slow and requires vitamin B6; 60 mg of tryptophan are required to make one milligram of niacin. Bacteria in the gut may also perform the conversion but are inefficient.

Nicotinic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=59-67-6 (retrieved 2024-06-29) (CAS RN: 59-67-6). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[1][2].
Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[1][2].

同义名列表

236 个代谢物同义名

Nicotinic acid, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=98\\%; Niacin (Nicotinic Acid), Pharmaceutical Secondary Standard; Certified Reference Material; Nicotinic acid, for inorganic trace analysis, >=99.999\\% (metals basis); Nicotinic acid, European Pharmacopoeia (EP) Reference Standard; Nicotinic acid, matrix substance for MALDI-MS, >=99.5\\% (HPLC); Niacin, United States Pharmacopeia (USP) Reference Standard; Nicotinic acid, certified reference material, TraceCERT(R); InChI=1/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9; Nicotinic acid, meets USP testing specifications; Nicotinic acid, Vetec(TM) reagent grade, >=98\\%; 5-22-02-00057 (Beilstein Handbook Reference); Nicotinic acid 10 microg/mL in Acetonitrile; Nicotinic acid, SAJ special grade, >=99.5\\%; METHYL NICOTINATE IMPURITY A [EP IMPURITY]; Nicotinic acid, plant cell culture tested; Nicotinic Acid [Matrix for MALDI-TOF/MS]; P.P. factor-pellagra preventive factor; Nicotinic acid, purum, >=99.0\\% (HPLC); 3DDB011E-F3A6-45B6-A2D2-77B2A6E8936E; Nicotinic Acid 1.0 mg/ml in Methanol; Nicotinic acid, for synthesis, 99\\%; Nicotinic acid, analytical standard; ACIDUM NICOTINICUM [WHO-IP LATIN]; Pyridine-carboxylique-3 [French]; Niacin Lithium Salt, Hemihydrate; Nicotinic acid, >=99.5\\% (HPLC); Pyridine-.beta.-carboxylic acid; Acido nicotinico [INN-Spanish]; Acide nicotinique [INN-French]; NIASPAN TITRATION STARTER PACK; Acidum nicotinicum [INN-Latin]; .beta.-Pyridinecarboxylic acid; Pyridine-beta-carboxylic acid; NICOTINIC ACID [EP MONOGRAPH]; beta-pyridinecarboxylic acid; NICOTINIC ACID [EP IMPURITY]; NIACIN COMPONENT OF ADVICOR; Kyselina nikotinova [Czech]; Pyridinecarboxylic acid, 3-; Nicotinic acid (Vitamin B3); Pyridine-b-carboxylic acid; 3-pyridine carboxylic acid; Pyridine-3-carboxylic acid; Pellagra preventive factor; Niacin Manganese (2+) Salt; NIACIN COMPONENT OF SIMCOR; Pyridine-β-carboxylic acid; 3-pyridinecarboxylic acid; Β-pyridinecarboxylic acid; 3-Pyridyl carboxylic acid; b-Pyridinecarboxylic acid; 3 Pyridinecarboxylic Acid; m-Pyridinecarboxylic acid; NICOTINIC ACID [EMA EPAR]; Nicotinic acid, USP grade; 5-pyridinecarboxylic acid; Nicotinic acid (JP17/INN); Pyridine-beta-carboxylate; 3-Pyridylcarboxylic acid; ADVICOR COMPONENT NIACIN; Nicotinic acid-d3(major); beta-Pyridinecarboxylate; Pyridine-3-carbonic acid; Pyridine-carboxylique-3; NICOTINIC ACID [WHO-DD]; NICOTINIC ACID [WHO-IP]; Niacin (nicotinic acid); Niacin Copper (2+) Salt; Niacin extended release; SIMCOR COMPONENT NIACIN; Niacin Cobalt (2+) Salt; Nicotinic acid (Niacin); NICOTINIC ACID [VANDF]; Nicotinic acid, >=98\\%; NIACIN [USP MONOGRAPH]; Pyridine-b-carboxylate; Nicotinic acid, Ph Eur; Pyridine-β-carboxylate; NICOTINIC ACID [MART.]; Potassium Salt, Niacin; b-Pyridinecarboxylate; Aluminum Salt, Niacin; Niacin Potassium Salt; Nicotinsaure [German]; Niacin Magnesium Salt; Niacin Iron (2+) Salt; anti-Pellagra vitamin; m-Pyridinecarboxylate; Β-pyridinecarboxylate; 3-Pyridinecarboxylate; Hydrochloride, Niacin; NICOTINIC ACID [JAN]; Nicotinic acid [INN]; NIACIN [ORANGE BOOK]; Niacin Aluminum Salt; antipellagra vitamin; Niacin Ammonium Salt; 3-Pyridylcarboxylate; Niacin Hydrochloride; Niacin Lithium Salt; [3H]-Nicotinic acid; Sodium Salt, Niacin; Kyselina nikotinova; Niacin Calcium Salt; NICOTINIC ACID [MI]; Nicotinate, Lithium; preventative factor; Nicotinic Acid,(S); 3-Carboxylpyridine; Acidum nicotinicum; Lithium Nicotinate; Niacin Sodium Salt; VITAMIN B3 [VANDF]; [3H]nicotinic acid; Prestwick2_000881; Prestwick3_000881; Prestwick0_000881; Prestwick1_000881; Acide nicotinique; 3-Carboxypyridine; Tartrate, Niacin; Acido nicotinico; Spectrum3_000515; Tosylate, Niacin; 3-Picolinic acid; Spectrum2_000006; Niacin Zinc Salt; Spectrum5_001287; Spectrum4_000965; [5, 6-3H]-niacin; Niacin Tosylate; Niacin Tartrate; NIACIN [USP-RS]; Nicotinic acid; NIACIN [VANDF]; Tox21_110337_1; Nicotinicacid; BPBio1_000730; NIACIN [INCI]; DivK1c_000695; Niacin [USAN]; NIACIN [HSDB]; Nikotinsaeure; Oprea1_514398; WLN: T6NJ CVQ; Nicotine acid; Niaspan (TN); Niacin (USP); Tox21_302904; KBio2_004111; KBio3_001569; KBio2_006679; Davitamon PP; NIACIN [FCC]; Tox21_110337; KBio2_001543; NCI60_001041; Nicotinsaure; Niacin [USP]; Tox21_201420; KBio1_000695; Niacor (TN); Nicocrisina; VITAMIN B-3; Nicotinipca; CAS-59-67-6; Nicodelmine; Pellagramin; IDI1_000695; P.P. factor; Vitamin B3; Slo-niacin; Vitaplex N; nicotinate; Ncotnc acd; Nicotinic; Nicotamin; Tega-Span; Nico-Span; Pellagrin; Niconazid; Apelagrin; Enduracin; Niconacid; Nicovasen; Nicovasan; Induracin; Nicosan 3; PP Factor; AI3-18994; Nicocidin; SK-Niacin; Nicangin; Nipellen; Nico-400; Nicotene; Nicoside; Direktan; Nico 400; wampocap; 3PyrCOOH; pellagra; Peviton; Nico400; Pelonin; nicobid; Niconat; Nicagin; Nicodon; Nicosyl; nicamin; nicolar; Niaspan; nicocap; Nicotil; niacine; Nicacid; niacin; Nyclin; Akotin; Efacin; Daskil; Niacor; Bionic; Diacin; Naotin; Linic; Tinic; Nicyl; NICO; Niac; NAH; NIO; Nicotinic acid(VB3); Nicotinate; Nicotinic acid



数据库引用编号

49 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(5)

BioCyc(1)

PlantCyc(2)

代谢反应

118 个相关的代谢反应过程信息。

Reactome(85)

BioCyc(3)

WikiPathways(3)

Plant Reactome(0)

INOH(2)

PlantCyc(13)

COVID-19 Disease Map(1)

PathBank(11)

  • Adenosylcobalamin Salvage from Cobinamide: Adenosine triphosphate + Cobinamide + Water ⟶ Adenosine diphosphate + Cobinamide + Hydrogen Ion + Phosphate
  • Adenosylcobalamin Salvage from Cobinamide: Adenosine triphosphate + Cyanocobalamin + Water ⟶ Adenosine diphosphate + Cyanocobalamin + Hydrogen Ion + Phosphate
  • NAD Salvage: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • NAD Salvage: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + Hydrogen Ion + L-Glutamic acid + NAD + Pyrophosphate
  • NAD Metabolism: N'-Formylkynurenine + Water ⟶ Formic acid + Hydrogen Ion + L-Kynurenine
  • Nicotinate and Nicotinamide Metabolism: NAD + Water ⟶ Adenosine monophosphate + Nicotinamide ribotide
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate
  • Nicotinate and Nicotinamide Metabolism: Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water ⟶ Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate

PharmGKB(0)

222 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AKT1, ALB, APOB, NAMPT, PCSK9, PPARG, PTGS2
Peripheral membrane protein 2 LPL, PTGS2
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 4 APOB, CD4, HMGCR, PTGS2
Nucleus 5 AKT1, ALB, NAMPT, PARP1, PPARG
cytosol 7 AKT1, ALB, APOB, NAMPT, NAPRT, PARP1, PPARG
nuclear body 1 PARP1
centrosome 1 ALB
nucleoplasm 3 AKT1, PARP1, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 5 AKT1, CD4, GPRC5A, LPL, PTGDR
lamellipodium 1 AKT1
Multi-pass membrane protein 4 GPRC5A, HCAR3, HMGCR, PTGDR
cell cortex 1 AKT1
cell junction 2 HCAR3, NAMPT
cell surface 3 CD38, LPL, PCSK9
glutamatergic synapse 1 AKT1
Golgi apparatus 2 ALB, PCSK9
lysosomal membrane 1 PCSK9
neuronal cell body 1 APOB
postsynapse 1 AKT1
smooth endoplasmic reticulum 1 APOB
Cytoplasm, cytosol 2 NAPRT, PARP1
Lysosome 1 PCSK9
endosome 1 PCSK9
plasma membrane 10 AKT1, APOB, CD38, CD4, GPRC5A, HCAR3, IFNLR1, LPL, PCSK9, PTGDR
Membrane 7 AKT1, CD38, HCAR3, HMGCR, IFNLR1, PARP1, PTGDR
basolateral plasma membrane 1 CD38
caveola 1 PTGS2
extracellular exosome 7 ALB, APOB, CD38, CETP, GPRC5A, NAMPT, NAPRT
endoplasmic reticulum 4 ALB, HMGCR, PCSK9, PTGS2
extracellular space 8 ALB, APOB, CETP, CRP, LPA, LPL, NAMPT, PCSK9
lysosomal lumen 1 APOB
perinuclear region of cytoplasm 2 PCSK9, PPARG
mitochondrion 1 PARP1
protein-containing complex 4 AKT1, ALB, PARP1, PTGS2
intracellular membrane-bounded organelle 3 APOB, GPRC5A, PPARG
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 2 CD4, IFNLR1
Secreted 7 ALB, APOB, CETP, CRP, LPL, NAMPT, PCSK9
extracellular region 8 ALB, APOB, CETP, CRP, LPA, LPL, NAPRT, PCSK9
Extracellular side 1 LPL
anchoring junction 1 ALB
transcription regulator complex 1 PARP1
nuclear membrane 1 CD38
external side of plasma membrane 1 CD4
Secreted, extracellular space, extracellular matrix 1 LPL
chylomicron 2 APOB, LPL
high-density lipoprotein particle 1 CETP
low-density lipoprotein particle 1 APOB
very-low-density lipoprotein particle 2 APOB, LPL
microtubule cytoskeleton 1 AKT1
nucleolus 2 GPRC5A, PARP1
Early endosome 3 APOB, CD4, PCSK9
cell-cell junction 1 AKT1
COPII-coated ER to Golgi transport vesicle 1 PCSK9
Single-pass type II membrane protein 1 CD38
vesicle 3 AKT1, CETP, GPRC5A
Membrane raft 1 CD4
spindle 1 AKT1
peroxisomal membrane 1 HMGCR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
nuclear speck 1 NAMPT
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 PCSK9
receptor complex 2 GPRC5A, PPARG
neuron projection 1 PTGS2
ciliary basal body 2 AKT1, ALB
chromatin 2 PARP1, PPARG
Chromosome 1 PARP1
centriole 1 ALB
Nucleus, nucleolus 1 PARP1
spindle pole 1 ALB
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
blood microparticle 1 ALB
site of double-strand break 1 PARP1
nuclear envelope 1 PARP1
endosome lumen 1 APOB
Lipid droplet 1 APOB
Cytoplasmic vesicle membrane 1 GPRC5A
Peroxisome membrane 1 HMGCR
endoplasmic reticulum lumen 5 ALB, APOB, CD4, PCSK9, PTGS2
platelet alpha granule lumen 1 ALB
azurophil granule lumen 1 NAPRT
endoplasmic reticulum exit site 1 APOB
clathrin-coated endocytic vesicle membrane 2 APOB, CD4
protein-DNA complex 1 PARP1
endolysosome membrane 1 PCSK9
extrinsic component of external side of plasma membrane 1 PCSK9
site of DNA damage 1 PARP1
endocytic vesicle lumen 1 APOB
PCSK9-LDLR complex 1 PCSK9
T cell receptor complex 1 CD4
chylomicron remnant 1 APOB
intermediate-density lipoprotein particle 1 APOB
mature chylomicron 1 APOB
catalytic complex 1 LPL
PCSK9-AnxA2 complex 1 PCSK9
plasma lipoprotein particle 1 LPA
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Vahid Ganjiani, Amin Bigham-Sadegh, Nasrollah Ahmadi, Mohammad-Reza Divar, Abdolhamid Meimandi-Parizi, Mohammad Asude. The potential prophylactic and therapeutic impacts of niacin on ischemia/reperfusion injury of testis. Journal of pediatric urology. 2024 Apr; 20(2):281.e1-281.e7. doi: 10.1016/j.jpurol.2024.01.001. [PMID: 38212166]
  • Ying Huang, Fang-Yuan Liu, Jia-Tao Yang, Qian Zhao, Mei-Qi Zhu, Jing Wang, Shi-Yin Long, Qin-Hui Tuo, Cai-Ping Zhang, Li-Mei Lin, Duan-Fang Liao. Curcumin nicotinate increases LDL cholesterol uptake in hepatocytes through IDOL/LDL-R pathway regulation. European journal of pharmacology. 2024 Jan; 966(?):176352. doi: 10.1016/j.ejphar.2024.176352. [PMID: 38290567]
  • Peng Li, Guoyao Wu. Characteristics of Nutrition and Metabolism in Dogs and Cats. Advances in experimental medicine and biology. 2024; 1446(?):55-98. doi: 10.1007/978-3-031-54192-6_4. [PMID: 38625525]
  • Nanjiba Nawaz, Tyler Mistretta, Christian Karime, Jason Lewis, Emily Wolf. Cholestatic Drug-Induced Liver Injury in a Patient Taking High-Dose Niacin for Hyperlipidemia. Journal of investigative medicine high impact case reports. 2024 Jan; 12(?):23247096231224349. doi: 10.1177/23247096231224349. [PMID: 38193433]
  • Camelia Munteanu, Betty Schwartz. B Vitamins, Glucoronolactone and the Immune System: Bioavailability, Doses and Efficiency. Nutrients. 2023 Dec; 16(1):. doi: 10.3390/nu16010024. [PMID: 38201854]
  • Somayeh Saboori, Esmaeil Yousefi Rad, Jonathan Tammam, Pariyarath Sangeetha Thondre, Shelly Coe. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials. The British journal of nutrition. 2023 Dec; ?(?):1-11. doi: 10.1017/s000711452300288x. [PMID: 38112076]
  • Shengnan Zhu, Qingning Yuan, Xinzhu Li, Xinheng He, Shiyi Shen, Dongxue Wang, Junrui Li, Xi Cheng, Xiaoqun Duan, H Eric Xu, Jia Duan. Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2. Cell reports. 2023 Nov; 42(11):113406. doi: 10.1016/j.celrep.2023.113406. [PMID: 37952153]
  • Maria D Octavia, Hasmiwati Hasmiwati, Gusti Revilla, Erizal Zaini. Effect of multicomponent crystal of piperine-nicotinic acid on antihyperlipidemic activity in rats. Pakistan journal of pharmaceutical sciences. 2023 Nov; 36(6):1777-1781. doi: . [PMID: 38124418]
  • Areeg Almubarak, Rana Osman, Joohyeong Lee, Il-Jeoung Yu, Yubyeol Jeon. Effects of niacin supplementation during in vitro culture on the developmental competence of porcine embryos. Reproduction in domestic animals = Zuchthygiene. 2023 Oct; ?(?):. doi: 10.1111/rda.14483. [PMID: 37786952]
  • Greggory R Davis, Arnold G Nelson. Niacin supplementation impairs exercise performance. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2023 Oct; 93(5):385-391. doi: 10.1024/0300-9831/a000736. [PMID: 34696617]
  • Nicolas Dugré, Adrienne J Lindblad, Danielle Perry, G Michael Allan, Émélie Braschi, Jamie Falk, Liesbeth Froentjes, Scott R Garrison, Jessica E M Kirkwood, Christina S Korownyk, James P McCormack, Samantha S Moe, Allison Paige, Jen Potter, Betsy S Thomas, Joey Ton, Jennifer Young, Justin Weresch, Michael R Kolber. Lipid-lowering therapies for cardiovascular disease prevention and management in primary care: PEER umbrella systematic review of systematic reviews. Canadian family physician Medecin de famille canadien. 2023 Oct; 69(10):701-711. doi: 10.46747/cfp.6910701. [PMID: 37833094]
  • Nouman Khurshid, Muhammad Adnan Bukhari, Tanveer Ahmad, Zahoor Ahmad, Wajid Nasim Jatoi, Syed Mohsin Abbas, Amir Latif, Amber Raza, Muhammad Aurangzaib, Abeer Hashem, Graciela Dolores Avila-Quezada, Elsayed Fathi Abd Allah. Exogenously applied nicotinic acid alleviates drought stress by enhancing morpho-physiological traits and antioxidant defense mechanisms in wheat. Ecotoxicology and environmental safety. 2023 Aug; 263(?):115350. doi: 10.1016/j.ecoenv.2023.115350. [PMID: 37586200]
  • Leiyong Zhao, Shanshan Guo, Jie Yang, Qingqing Wang, Xixue Lu. Association between niacin intake and depression: A nationwide cross-sectional study. Journal of affective disorders. 2023 Aug; ?(?):. doi: 10.1016/j.jad.2023.08.053. [PMID: 37572704]
  • Joyati Das, Rahul Kumar, Sunil Kumar Yadav, Gopaljee Jha. Nicotinic Acid Catabolism Modulates Bacterial Mycophagy in Burkholderia gladioli Strain NGJ1. Microbiology spectrum. 2023 06; 11(3):e0445722. doi: 10.1128/spectrum.04457-22. [PMID: 37014254]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
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