Thymidine (BioDeep_00000000073)

 

Secondary id: BioDeep_00000398589

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

化学式: C10H14N2O5 (242.0903)
中文名称: β-胸苷, 胸苷
谱图信息: 最多检出来源 Homo sapiens(blood) 14.94%

Reviewed

Last reviewed on 2024-11-05.

Cite this Page

Thymidine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/thymidine (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000073). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
InChI: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1

描述信息

Deoxythymidine, also known as 2-deoxy-5-methyluridine or 5-methyl-2-deoxyuridine, is a member of the class of compounds known as pyrimidine 2-deoxyribonucleosides. Pyrimidine 2-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. Deoxythymidine is soluble (in water) and a very weakly acidic compound (based on its pKa). Deoxythymidine can be synthesized from thymine. Deoxythymidine is also a parent compound for other transformation products, including but not limited to, tritiated thymidine, alpha-tritiated thymidine, and 5,6-dihydrothymidine. Deoxythymidine can be found in a number of food items such as butternut squash, mammee apple, catjang pea, and climbing bean, which makes deoxythymidine a potential biomarker for the consumption of these food products. Deoxythymidine can be found primarily in most biofluids, including blood, amniotic fluid, cerebrospinal fluid (CSF), and urine, as well as throughout most human tissues. Deoxythymidine exists in all living species, ranging from bacteria to humans. In humans, deoxythymidine is involved in the pyrimidine metabolism. Deoxythymidine is also involved in few metabolic disorders, which include beta ureidopropionase deficiency, dihydropyrimidinase deficiency, MNGIE (mitochondrial neurogastrointestinal encephalopathy), and UMP synthase deficiency (orotic aciduria). Moreover, deoxythymidine is found to be associated with canavan disease and degenerative disc disease. Thymidine (deoxythymidine; other names deoxyribosylthymine, thymine deoxyriboside) is a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in G1/early S phase .
Thymidine, also known as deoxythymidine or deoxyribosylthymine or thymine deoxyriboside, is a pyrimidine deoxynucleoside. It consists of the nucleobase thymine attached to deoxyribose through a beta N- glycosidic bond. Thymidine also belongs to the class of organic compounds known as pyrimidine 2-deoxyribonucleosides. Pyrimidine 2-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. Deoxythymidine (or thymidine) is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. Therefore, thymidine is essential to all life. Indeed, thymidine exists in all living species, ranging from bacteria to plants to humans. Within humans, thymidine participates in a number of enzymatic reactions. In particular, thymidine can be biosynthesized from 5-thymidylic acid through its interaction with the enzyme cytosolic purine 5-nucleotidase. In addition, thymidine can be converted into 5-thymidylic acid; which is catalyzed by the enzyme thymidine kinase. Deoxythymidine can be phosphorylated with one, two or three phosphoric acid groups, creating dTMP (deoxythymidine monophosphate), dTDP, or dTTP (for the di- and tri- phosphates, respectively). dTMP can be incorporated into DNA via DNA polymerases. In cell biology, thymidine can be used to synchronize the cells in S phase. Derivatives of thymidine are used in a number of drugs, including Azidothymidine (AZT), which is used in the treatment of HIV infection. AZT inhibits the process of reverse transcription in the human immunodeficiency virus.
Thymidine is a pyrimidine 2-deoxyribonucleoside having thymine as the nucleobase. It has a role as a metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a thymine. It is an enantiomer of a telbivudine.
Thymidine is a pyrimidine deoxynucleoside. Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in S phase.
Thymidine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Thymidine is a natural product found in Fritillaria thunbergii, Saussurea medusa, and other organisms with data available.
Thymidine is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. As a constituent of DNA, thymidine pairs with adenine in the DNA double helix. (NCI04)
Thymidine is a metabolite found in or produced by Saccharomyces cerevisiae.
A nucleoside in which THYMINE is linked to DEOXYRIBOSE.
A pyrimidine 2-deoxyribonucleoside having thymine as the nucleobase.
KEIO_ID T014; [MS2] KO009272
KEIO_ID T014
Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].
Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

同义名列表

87 个代谢物同义名

1-(2-Deoxy-beta-D-ribofuranosyl)-5-methyluracil; 1-(2-Deoxy-beta-D-ribofuranosyl)thymine; Thymine deoxyriboside; 2-Deoxythymidine; 5-Methyldeoxyuridine; 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-furan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(4S,2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-dihydropyri midine-2,4-dione; 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione; 1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione (Thymidine); 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE [WHO-IP]; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione; 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Deoxy-beta-delta-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-; 1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione; Thymidine, powder, BioReagent, suitable for cell culture; 1-(2-Deoxy-.beta.-D-ribofuranosyl)-5-methyluracil; 1-(2-Deoxy-beta-ribofuranosyl)-5-methyluracil; thymine-1 2-deoxy-beta-delta-Ribofuranoside; beta-D-Ribofuranoside, thymine-1 2-deoxy-; Thymidine, Vetec(TM) reagent grade, 99\\%; D7E43A69-265B-4DAA-BC8F-193FB357140F; thymine-1 2-deoxy-b-D-Ribofuranoside; ZIDOVUDINE IMPURITY E [EP IMPURITY]; STAVUDINE IMPURITY C [EP IMPURITY]; DEOXYTHYMIDINE; 2-DEOXYTHYMIDINE; STAVUDINE IMPURITY C [WHO-IP]; IQFYYKKMVGJFEH-XLPZGREQSA-N; Uridine, 2-deoxy-5-methyl-; Thymidine, >=99.0\\% (HPLC); alpha-tritiated thymidine; 2-deoxy-5-methyl-Uridine; IMPURITY C [EP IMPURITY]; Thymine 2-desoxyriboside; Thymine-2-desoxyriboside; 5-Methyl-2-deoxyuridine; Thymine-2-deoxyriboside; 2-deoxy-5-methyluridine; thymine 2-deoxyriboside; beta-Methyldeoxyuridine; Thymidinedeoxyriboside; Thymine deoxyriboside; 5-Methyldeoxyurindine; 5-Methyldeoxyuridine; Thyminedeoxyriboside; DOXRIBTIMINE [USAN]; deoxyribosylthymine; Thymidine (8CI,9CI); THYMIDINE [WHO-IP]; DOXRIBTIMINE [INN]; THYMIDINE [WHO-DD]; Deoxyribothymidine; Thymidine, >=99\\%; THYMIDINE [MART.]; 2-Deoxythymidine; 2 Deoxythymidine; THYMIDINE [INCI]; UNII-VC2W18DGKR; Beta-Thymidine; THYMIDINE [MI]; [3H]-Thymidine; deoxythymidine; Tox21_111560; Doxribtimine; 2-thymidine; CAS-50-89-5; VC2W18DGKR; Thymidine; AI3-52267; Thymidin; BDBM1; DThyd; 4qsv; dThd; 1w2g; 2-dT; THM; dT; T; L-Thymidine; Thymidine; NSC 21548; Thymidine; Thymidine



数据库引用编号

48 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(2)

BioCyc(7)

PlantCyc(0)

代谢反应

431 个相关的代谢反应过程信息。

Reactome(56)

BioCyc(104)

WikiPathways(2)

Plant Reactome(0)

INOH(2)

PlantCyc(246)

COVID-19 Disease Map(0)

PathBank(21)

PharmGKB(0)

210 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ALB, ANG, CAT, CDKN1A, DHFR, EDN1, ODC1, PRKX, TK2, TYMS
Endoplasmic reticulum membrane 1 CD4
Nucleus 6 ALB, ANG, CDKN1A, PCNA, PRKX, TYMS
cytosol 9 ALB, ANG, CAT, CDKN1A, DHFR, ODC1, PRKCQ, TYMP, TYMS
nuclear body 2 CDKN1A, PCNA
centrosome 2 ALB, PCNA
nucleoplasm 3 CDKN1A, PCNA, PRKX
Cell membrane 2 CD4, TNF
cell surface 1 TNF
Golgi apparatus 1 ALB
Golgi membrane 1 INS
growth cone 1 ANG
lysosomal membrane 1 EGF
mitochondrial inner membrane 1 TYMS
neuronal cell body 2 ANG, TNF
plasma membrane 5 CD4, EGF, IFNLR1, PRKCQ, TNF
Membrane 3 CAT, EGF, IFNLR1
extracellular exosome 4 ALB, CAT, EGF, PCNA
endoplasmic reticulum 1 ALB
extracellular space 8 ALB, ANG, EDN1, EGF, IGF1, IL2, INS, TNF
perinuclear region of cytoplasm 1 CDKN1A
mitochondrion 4 CAT, DHFR, TK2, TYMS
protein-containing complex 3 ALB, CAT, CDKN1A
intracellular membrane-bounded organelle 1 CAT
Single-pass type I membrane protein 2 CD4, IFNLR1
Secreted 6 ALB, ANG, EDN1, IGF1, IL2, INS
extracellular region 9 ALB, ANG, CAT, EDN1, EGF, IGF1, IL2, INS, TNF
basal part of cell 1 EDN1
Mitochondrion matrix 1 TYMS
mitochondrial matrix 3 CAT, TK2, TYMS
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
external side of plasma membrane 2 CD4, TNF
actin cytoskeleton 1 ANG
nucleolus 2 ANG, CDKN1A
Early endosome 1 CD4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Mitochondrion inner membrane 1 TYMS
Membrane raft 2 CD4, TNF
focal adhesion 1 CAT
Peroxisome 1 CAT
basement membrane 1 ANG
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
ciliary basal body 1 ALB
chromatin 1 PCNA
phagocytic cup 1 TNF
Chromosome 1 ANG
centriole 1 ALB
Nucleus, nucleolus 1 ANG
spindle pole 1 ALB
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
blood microparticle 1 ALB
endosome lumen 1 INS
Cytoplasm, Stress granule 1 ANG
cytoplasmic stress granule 1 ANG
replication fork 1 PCNA
exocytic vesicle 1 IGF1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, CD4, INS
male germ cell nucleus 1 PCNA
platelet alpha granule lumen 3 ALB, EGF, IGF1
endocytic vesicle 1 ANG
transport vesicle 2 EDN1, INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
nuclear lamina 1 PCNA
clathrin-coated endocytic vesicle membrane 2 CD4, EGF
cyclin-dependent protein kinase holoenzyme complex 2 CDKN1A, PCNA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
angiogenin-PRI complex 1 ANG
rough endoplasmic reticulum lumen 1 EDN1
catalase complex 1 CAT
Weibel-Palade body 1 EDN1
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
PCNA complex 1 PCNA
PCNA-p21 complex 2 CDKN1A, PCNA
replisome 1 PCNA
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Naoki Fukui, Takuya Fujiwara, Masakazu Furuta, Satoshi Takatori. [Detection of Gamma-Ray Irradiation History of Dried Plant-Based Foods via the Analysis of 5,6-Dihydrothymidine]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan. 2023; 64(6):206-213. doi: 10.3358/shokueishi.64.206. [PMID: 38171890]
  • Fan Yang, Xiaoqiang Shi, Weidong Yang, Chao Gao, Zhenyu Cui, Wentao Wang. Pueraria montana (Kudzu vine) Ameliorate the Inflammation and Oxidative Stress against Fe-NTA Induced Renal Cancer. Journal of oleo science. 2022 Sep; 71(10):1481-1492. doi: 10.5650/jos.ess22151. [PMID: 36089399]
  • Markus Niehaus, Henryk Straube, André Specht, Chiara Baccolini, Claus-Peter Witte, Marco Herde. The nucleotide metabolome of germinating Arabidopsis thaliana seeds reveals a central role for thymidine phosphorylation in chloroplast development. The Plant cell. 2022 09; 34(10):3790-3813. doi: 10.1093/plcell/koac207. [PMID: 35861422]
  • Mohammed Anowar Hosen, Nasrin Sultana Munia, Mohammed Al-Ghorbani, Mohammed Baashen, Faisal A Almalki, Taibi Ben Hadda, Ferdausi Ali, Shafi Mahmud, Md Abu Saleh, Hamid Laaroussi, Sarkar M A Kawsar. Synthesis, antimicrobial, molecular docking and molecular dynamics studies of lauroyl thymidine analogs against SARS-CoV-2: POM study and identification of the pharmacophore sites. Bioorganic chemistry. 2022 08; 125(?):105850. doi: 10.1016/j.bioorg.2022.105850. [PMID: 35533581]
  • Chao Gao, Long Zhang, Enuo Chen, Wenzheng Zhang. Aqp2+ Progenitor Cells Maintain and Repair Distal Renal Segments. Journal of the American Society of Nephrology : JASN. 2022 07; 33(7):1357-1376. doi: 10.1681/asn.2021081105. [PMID: 35318267]
  • Christine K Iwahashi, Jonathan Kopel, Harrison Marsh, Ted W Reid. Effects of Dexamethasone on DNA Synthesis in Lens Epithelial Cells Are Dependent on Cell Type and Growth Factor. Current eye research. 2022 07; 47(7):1009-1015. doi: 10.1080/02713683.2022.2052106. [PMID: 35260019]
  • Julie Høgh, Malene Hove-Skovsgaard, Marco Gelpi, Anne Marie Reimer Jensen, Jan Gerstoft, Thomas Benfield, Heidi Storgaard, Susanne Dam Nielsen. Insulin resistance in people living with HIV is associated with exposure to thymidine analogues and/or didanosine and prior immunodeficiency. BMC infectious diseases. 2022 May; 22(1):503. doi: 10.1186/s12879-022-07485-1. [PMID: 35643429]
  • Dmitry I Maltsev, Kennelia A Mellanson, Vsevolod V Belousov, Grigori N Enikolopov, Oleg V Podgorny. The bioavailability time of commonly used thymidine analogues after intraperitoneal delivery in mice: labeling kinetics in vivo and clearance from blood serum. Histochemistry and cell biology. 2022 Feb; 157(2):239-250. doi: 10.1007/s00418-021-02048-y. [PMID: 34757474]
  • Ayesha Rahman Ahmed, Senty Vun-Sang, Mohammad Iqbal. Therapeutic role of nitroglycerin against copper-nitrilotriacetate induced hepatic and renal damage. Human & experimental toxicology. 2022 Jan; 41(?):9603271221131312. doi: 10.1177/09603271221131312. [PMID: 36305384]
  • Omar D Subedar, Loraine L Y Chiu, Stephen D Waldman. Cell Cycle Synchronization of Primary Articular Chondrocytes Enhances Chondrogenesis. Cartilage. 2021 10; 12(4):526-535. doi: 10.1177/1947603519841677. [PMID: 30971093]
  • Nurjannatul Naim Kamaruddin, Nor Azwin Hajri, Yosie Andriani, Aina Farahiyah Abdul Manan, Tengku Sifzizul Tengku Muhammad, Habsah Mohamad. Acanthaster planci Inhibits PCSK9 and Lowers Cholesterol Levels in Rats. Molecules (Basel, Switzerland). 2021 Aug; 26(16):. doi: 10.3390/molecules26165094. [PMID: 34443682]
  • Jessie W Yester, Honghai Liu, Frank Gyngard, Niyatie Ammanamanchi, Kathryn C Little, Dawn Thomas, Mara L G Sullivan, Sean Lal, Matthew L Steinhauser, Bernhard Kühn. Use of stable isotope-tagged thymidine and multi-isotope imaging mass spectrometry (MIMS) for quantification of human cardiomyocyte division. Nature protocols. 2021 04; 16(4):1995-2022. doi: 10.1038/s41596-020-00477-y. [PMID: 33627842]
  • Antonio Mancini, Francesco Guidi, Carmine Bruno, Flavia Angelini, Edoardo Vergani, Paola Lanza, Alvaro Mordente, Elisabetta Meucci, Andrea Silvestrini. Can plasma antioxidants prevent DNA damage in oxidative stress condition induced by growth hormone deficiency? A pilot study. PloS one. 2021; 16(4):e0248971. doi: 10.1371/journal.pone.0248971. [PMID: 33793606]
  • Leila Darki, Arash Jalali-Sohi, Said R Beydoun. Polyneuropathy Reveals Origins of Decade-long Gastrointestinal Symptoms in a Patient With Undiagnosed Mitochondrial Neurogastrointestinal Encephalopathy Caused by a Novel Mutation. Journal of clinical neuromuscular disease. 2020 Dec; 22(2):97-102. doi: 10.1097/cnd.0000000000000326. [PMID: 33214395]
  • Natsumi Nagano, Yoshiyuki Kawakami, Takehisa Matsumoto, Koichi Tanimoto, Masami Kashihara, Megumi Nagata, Hideyasu Honjyo, Konosuke Yamamoto, Atsuaki Takada, Tetsuro Sugiura. Isolation of thymidine-dependent and extended-spectrum-β-lactamase-producing Escherichia coli small-colony variant from urine of a septuagenarian female patient with recurrent cystitis: A case report with genetic investigation. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 2020 Oct; 26(10):1066-1069. doi: 10.1016/j.jiac.2020.05.013. [PMID: 32571646]
  • Brandon J Eudy, Caitlin E McDermott, Gabriel Fernandez, Clayton E Mathews, Jinping Lai, Robin P da Silva. Disruption of hepatic one-carbon metabolism impairs mitochondrial function and enhances macrophage activity in methionine-choline-deficient mice. The Journal of nutritional biochemistry. 2020 07; 81(?):108381. doi: 10.1016/j.jnutbio.2020.108381. [PMID: 32422424]
  • Cancan Yang, Jing Li, Zhenling Huang, Xuefa Zhang, Xiaolei Gao, Chunyuang Zhu, Paul F Morris, XiuGuo Zhang. Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici. Scientific reports. 2020 06; 10(1):9051. doi: 10.1038/s41598-020-65935-9. [PMID: 32493959]
  • KimberlyA Kripps, Warapan Nakayuenyongsuk, Brian J Shayota, William Berquist, Natalia Gomez-Ospina, Carlos O Esquivel, Waldo Concepcion, Jacinda B Sampson, David J Cristin, Whitney E Jackson, Samuel Gilliland, Elizabeth A Pomfret, Michael L Kueht, Rowland W Pettit, Youmna A Sherif, Lisa T Emrick, Sarah H Elsea, Ryan Himes, Michio Hirano, Johan L K Van Hove, Fernando Scaglia, Gregory M Enns, Austin A Larson. Successful liver transplantation in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). Molecular genetics and metabolism. 2020 05; 130(1):58-64. doi: 10.1016/j.ymgme.2020.03.001. [PMID: 32173240]
  • Wei Guo, Xia Wu, Yi Li, Jixue Gao, Feng Wang, Yongsheng Jin, Tie Chong, Anshoo Malhotra. Evaluation of biophysical as well as biochemical potential of curcumin and resveratrol during prostate cancer. Journal of drug targeting. 2020 01; 28(1):41-45. doi: 10.1080/1061186x.2019.1601199. [PMID: 30943812]
  • Fanglin Ming, Jingzhou Hou, Changjun Hou, Mei Yang, Xianfeng Wang, Jiawei Li, Danqun Huo, Qiang He. One-step synthesized fluorescent nitrogen doped carbon dots from thymidine for Cr (VI) detection in water. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2019 Nov; 222(?):117165. doi: 10.1016/j.saa.2019.117165. [PMID: 31185440]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Marco Gelpi, Andreas Dehlbæk Knudsen, Karoline Brostrup Larsen, Amanda Mocroft, Anne-Mette Lebech, Birgitte Lindegaard, Jens Lundgren, Klaus Fuglsang Kofoed, Susanne Dam Nielsen. Long-lasting alterations in adipose tissue density and adiponectin production in people living with HIV after thymidine analogues exposure. BMC infectious diseases. 2019 Aug; 19(1):708. doi: 10.1186/s12879-019-4347-y. [PMID: 31399063]
  • Christelle Guillermier, Sean P Doherty, Adam G Whitney, Vladimir R Babaev, MacRae F Linton, Matthew L Steinhauser, Jonathan D Brown. Imaging mass spectrometry reveals heterogeneity of proliferation and metabolism in atherosclerosis. JCI insight. 2019 06; 4(11):. doi: 10.1172/jci.insight.128528. [PMID: 31167964]
  • A V Kara, Y Yıldırım, F Ozcicek, M N Aldemir, Y Arslan, K Bayan, M K Çelen. Effects of entecavir, tenofovir and telbivudine treatment on renal functions in chronic hepatitis B patients. Acta gastro-enterologica Belgica. 2019 Apr; 82(2):273-277. doi: . [PMID: 31314188]
  • Yi Ning, Jue Hu, Ke Wei, Guliang He, Tao Wu, Fangguo Lu. Fluorometric determination of mercury(II) via a graphene oxide-based assay using exonuclease III-assisted signal amplification and thymidine-Hg(II)-thymidine interaction. Mikrochimica acta. 2019 03; 186(4):216. doi: 10.1007/s00604-019-3332-x. [PMID: 30838468]
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