Curcumin (BioDeep_00000003752)

Main id: BioDeep_00000017309

Secondary id: BioDeep_00000171554

natural product PANOMIX_OTCML-2023 Volatile Flavor Compounds


代谢物信息卡片


InChI=1\C21H20O6\c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2\h3-13,22,24-25H,1-2H3\b7-3+,8-4+,16-13

化学式: C21H20O6 (368.125982)
中文名称: 姜黄油, 姜黄素
谱图信息: 最多检出来源 Viridiplantae(plant) 0.9%

分子结构信息

SMILES: C1(=C(C=CC(=C1)/C=C/C(/C=C(/C=C/C2=CC=C(C(=C2)OC)O)O)=O)O)OC
InChI: InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

描述信息

C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.286
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor
D000893 - Anti-Inflammatory Agents
D000970 - Antineoplastic Agents
D018501 - Antirheumatic Agents
D004791 - Enzyme Inhibitors
D004396 - Coloring Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.290
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.289
[Raw Data] CBA71_Curcumin_neg_10eV.txt
[Raw Data] CBA71_Curcumin_neg_30eV.txt
[Raw Data] CBA71_Curcumin_neg_40eV.txt
[Raw Data] CBA71_Curcumin_pos_30eV.txt
[Raw Data] CBA71_Curcumin_pos_20eV.txt
[Raw Data] CBA71_Curcumin_pos_40eV.txt
[Raw Data] CBA71_Curcumin_neg_50eV.txt
[Raw Data] CBA71_Curcumin_pos_10eV.txt
[Raw Data] CBA71_Curcumin_pos_50eV.txt
[Raw Data] CBA71_Curcumin_neg_20eV.txt
Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.

同义名列表

25 个代谢物同义名

InChI=1\C21H20O6\c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2\h3-13,22,24-25H,1-2H3\b7-3+,8-4+,16-13; (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxy-phenyl)hepta-1,4,6-trien-3-one; (1E,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one; 5-hydroxy-1,7-bis(4-hydroxy-3-methoxy-phenyl)hepta-1,4,6-trien-3-one; 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one; SDCCGMLS-0066836.P001; Spectrum2_001714; Spectrum3_001990; SpecPlus_000587; NCGC00095321-01; BSPBio_003590; DivK1c_006683; SPBio_001728; ZINC00899824; KBio3_003004; KBio1_001627; Kacha haldi; 458-37-7; Curcumin; C10443; Curcuma oil; Diferuloylmethane; Natural Yellow 3; Turmeric yellow; Curcumin



数据库引用编号

72 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(1)

代谢反应

64 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(6)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(57)

COVID-19 Disease Map(0)

PathBank(1)

PharmGKB(0)

138 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jawaharlal Nehru Garimella, Rama Chandra Pradhan. Effect of (multi pin) atmospheric cold plasma treatment on curcumin extraction and investigating phytochemicals, antioxidants, physical and morphological properties of turmeric (Curcuma longa L.) powder. Food chemistry. 2024 Aug; 449(?):139233. doi: 10.1016/j.foodchem.2024.139233. [PMID: 38593725]
  • Pengmin Zhang, Shuang Li, Wenxiu Wang, Jianfeng Sun, Zhizhou Chen, Jie Wang, Qianyun Ma. Enhanced photodynamic inactivation against Escherichia coli O157:H7 provided by chitosan/curcumin coating and its application in food contact surfaces. Carbohydrate polymers. 2024 Aug; 337(?):122160. doi: 10.1016/j.carbpol.2024.122160. [PMID: 38710575]
  • Yuying Wang, Jing Shen, Bowen Zou, Ling Zhang, Xianbing Xu, Chao Wu. Unveiling the critical pH values triggering the unfolding of soy 7S and 11S globulins and enhancing their encapsulation efficiency. Food chemistry. 2024 Jul; 445(?):138707. doi: 10.1016/j.foodchem.2024.138707. [PMID: 38354644]
  • Malihe Keramat, Mohammad-Taghi Golmakani. Antioxidant potency and inhibitory mechanism of curcumin and its derivatives in oleogel and emulgel produced by linseed oil. Food chemistry. 2024 Jul; 445(?):138754. doi: 10.1016/j.foodchem.2024.138754. [PMID: 38364496]
  • Wujiao Wang, Peifen Chang, Jialin Jin, Fenglan Pu, Dan Li, Ying Bai, Ke Dong, Qingshu Yang, Tianli Li. Cardioprotective effects of curcumin against Diabetic Cardiomyopathies: A systematic review and meta-analysis of preclinical studies. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155619. doi: 10.1016/j.phymed.2024.155619. [PMID: 38723524]
  • Hualu Zhou, Giang Vu, Qian Ju, David Julian McClements. Development of plant-based whole egg analogs using emulsion technology. Food research international (Ottawa, Ont.). 2024 Jul; 187(?):114406. doi: 10.1016/j.foodres.2024.114406. [PMID: 38763658]
  • Qi Wang, Shizhang Yan, Yijie Ning, Yan Zhu, Irina Sergeeva, Yang Li, Baokun Qi. Effect of sodium alginate block type on the physicochemical properties and curcumin release behavior of quaternized chitosan-oxidized sodium alginate Schiff base hydrogels. Food chemistry. 2024 Jun; 444(?):138688. doi: 10.1016/j.foodchem.2024.138688. [PMID: 38341919]
  • Mohammad Mehdi Nemati, Mehdi Abedi, Younes Ghasemi, Hajar Ashrafi, Mobin Haghdel. Formulation and evaluation of antioxidant and antibacterial activity of a peel-off facial masks moisturizer containing curcumin and Rosa Damascena extract. Journal of cosmetic dermatology. 2024 Jun; 23(6):2156-2169. doi: 10.1111/jocd.16255. [PMID: 38406887]
  • Jia-Feng Duan, Qiu-Juan Zhang, Jin Zhu, Jia-Hui Lu. Curcumin affects autophagy of prolactinoma cells by upregulating miR-206 to exert antitumor effects. Journal of biochemical and molecular toxicology. 2024 Jun; 38(6):e23734. doi: 10.1002/jbt.23734. [PMID: 38764151]
  • Mehran Izadi, Nariman Sadri, Amirhossein Abdi, Mohammad Mahdi Raeis Zadeh, Dorsa Jalaei, Mohammad Mahdi Ghazimoradi, Sara Shouri, Safa Tahmasebi. Longevity and anti-aging effects of curcumin supplementation. GeroScience. 2024 Jun; 46(3):2933-2950. doi: 10.1007/s11357-024-01092-5. [PMID: 38409646]
  • Rajkumar Vasanthkumar, Venkidasamy Baskar, Sathasivam Vinoth, Kattilaparambil Roshna, Thomas Nancy Mary, Raman Alagupandi, Krishnagowdu Saravanan, Ramalingam Radhakrishnan, Muthukrishnan Arun, Packiaraj Gurusaravanan. Biogenic carbon quantum dots from marine endophytic fungi (Aspergillus flavus) to enhance the curcumin production and growth in Curcuma longa L. Plant physiology and biochemistry : PPB. 2024 Jun; 211(?):108644. doi: 10.1016/j.plaphy.2024.108644. [PMID: 38710114]
  • Jing Ni, Yue Zhang, Shaowei Zhai, Hejian Xiong, Yanlin Ming, Ying Ma. Preparation of valine-curcumin conjugate and its in vitro antibacterial and antitumor activity and in vivo biological effects on American eels (Anguilla rostrata). Fish & shellfish immunology. 2024 Jun; 149(?):109615. doi: 10.1016/j.fsi.2024.109615. [PMID: 38719095]
  • Chanda Javed, Razia Noreen, Samia Gul Niazi, Mubin Mustafa Kiyani, Qurat Ul Ain. Anti-gouty arthritis and anti-inflammatory effects of curcumin nanoparticles in monosodium urate crystals induced Balb/C mice. Inflammopharmacology. 2024 Jun; 32(3):1929-1940. doi: 10.1007/s10787-024-01450-x. [PMID: 38556563]
  • Gulsah Karabulut, Hao Feng. Enhancing techno-functional attributes of plant protein and curcumin complexation: A comparative examination of Maillard conjugation induced by manothermosonication and ultrasonication. Food chemistry. 2024 Jun; 442(?):138488. doi: 10.1016/j.foodchem.2024.138488. [PMID: 38244438]
  • Maryam Wahab, Srinivas Janaswamy. Porous corn starch granules as effective host matrices for encapsulation and sustained release of curcumin and resveratrol. Carbohydrate polymers. 2024 Jun; 333(?):121967. doi: 10.1016/j.carbpol.2024.121967. [PMID: 38494222]
  • Huiping Tao, Lihan Shen. RESEARCH PROGRESS OF CURCUMIN IN THE TREATMENT OF SEPSIS. Shock (Augusta, Ga.). 2024 Jun; 61(6):805-816. doi: 10.1097/shk.0000000000002342. [PMID: 38664750]
  • Meiqi Chang, Lu Zhang, Tingting Zhang, Yanqiu Duan, Wei Feng, Shaoling Yang, Yu Chen, Zeyu Wang. Ultrasound-augmented enzyodynamic-Ca2+ overload synergetic tumor nanotherapy. Biomaterials. 2024 Jun; 307(?):122513. doi: 10.1016/j.biomaterials.2024.122513. [PMID: 38432005]
  • Leilei Zhang, Gokhan Zengin, Ceyda Ozfidan-Konakci, Evren Yildiztugay, Busra Arikan, Rumeysa Ekim, Buket Koyukan, Fevzi Elbasan, Luigi Lucini. Exogenous curcumin mitigates As stress in spinach plants: A biochemical and metabolomics investigation. Plant physiology and biochemistry : PPB. 2024 Jun; 211(?):108713. doi: 10.1016/j.plaphy.2024.108713. [PMID: 38739963]
  • Daniela Pastorim Vaiss, Jamile Lima Rodrigues, Virginia Campello Yurgel, Frank do Carmo Guedes, Lauanda Larissa Mendonça da Matta, Paula Alice Bezerra Barros, Gustavo Richter Vaz, Raíssa Nunes Dos Santos, Bibiana Franzen Matte, Larine Kupski, Jaqueline Garda-Buffon, Juliana Bidone, Ana Luiza Muccillo-Baisch, Fabio Sonvico, Cristiana Lima Dora. Curcumin and quercetin co-encapsulated in nanoemulsions for nasal administration: A promising therapeutic and prophylactic treatment for viral respiratory infections. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2024 Jun; 197(?):106766. doi: 10.1016/j.ejps.2024.106766. [PMID: 38615970]
  • Cristina Matthewman, I M Krishnakumar, Andrew G Swick. Review: bioavailability and efficacy of 'free' curcuminoids from curcumagalactomannoside (CGM) curcumin formulation. Nutrition research reviews. 2024 Jun; 37(1):14-31. doi: 10.1017/s0954422423000033. [PMID: 36655498]
  • Sineenart Sanpinit, Julalak Chokpaisarn, Pinanong Na-Phatthalung, Dennapa Saeloh Sotthibandhu, Kanyatorn Yincharoen, Palika Wetchakul, Surasak Limsuwan, Sasitorn Chusri. Effectiveness of Ya-Samarn-Phlae in diabetic wound healing: Evidence from in vitro studies and a multicenter randomized controlled clinical trial. Journal of ethnopharmacology. 2024 May; 326(?):117929. doi: 10.1016/j.jep.2024.117929. [PMID: 38373661]
  • Esha S Attar, S Jayakumar, Padma V Devarajan. Oral In-Situ Nanoplatform with Balanced Hydrophobic-Hydrophilic Property for Transport Across Gastrointestinal Mucosa. AAPS PharmSciTech. 2024 May; 25(5):113. doi: 10.1208/s12249-024-02824-8. [PMID: 38750336]
  • Tiago Nicoliche, Cynthia Silva Bartolomeo, Robertha Mariana Rodrigues Lemes, Gabriela Cruz Pereira, Tamires Alves Nunes, Rafaela Brito Oliveira, Arthur Luiz Miranda Nicastro, Érica Novaes Soares, Brenno Fernandes da Cunha Lima, Beatriz Moreira Rodrigues, Juliana Terzi Maricato, Liria Hiromi Okuda, Mirela Inês de Sairre, Carla Máximo Prado, Rodrigo Portes Ureshino, Roberta Sessa Stilhano. Antiviral, anti-inflammatory and antioxidant effects of curcumin and curcuminoids in SH-SY5Y cells infected by SARS-CoV-2. Scientific reports. 2024 05; 14(1):10696. doi: 10.1038/s41598-024-61662-7. [PMID: 38730068]
  • Xiaoxia Zhou, Xufang Ying, Linjie Wu, Liqin Liu, Ying Wang, Ying He, Min Han. Research Progress of Natural Product Photosensitizers in Photodynamic Therapy. Planta medica. 2024 May; 90(5):368-379. doi: 10.1055/a-2257-9194. [PMID: 38423033]
  • Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzadeh. The ameliorative effect of turmeric (Curcuma longa Linn) extract and its major constituent, curcumin, and its analogs on ethanol toxicity. Phytotherapy research : PTR. 2024 May; 38(5):2165-2181. doi: 10.1002/ptr.8165. [PMID: 38396341]
  • Narsaiah Chelimela, Rajasekhar Reddy Alavala, Shobha Rani Satla. Curcumin - Bioavailability Enhancement by Prodrug Approach and Novel Formulations. Chemistry & biodiversity. 2024 May; 21(5):e202302030. doi: 10.1002/cbdv.202302030. [PMID: 38401117]
  • Li-Chan Yang, Chih-Chiang Wang, Der-Yen Lee, Wen-Chuan Lin, Sheng-Chu Kuo, Shin-Hun Juang, Min-Tsang Hsieh. 4,4-Diallyl curcumin bis(2,2-hydroxymethyl)propanoate ameliorates nonalcoholic steatohepatitis in methionine-choline-deficient diet and Western diet mouse models. Chemical biology & drug design. 2024 May; 103(5):e14532. doi: 10.1111/cbdd.14532. [PMID: 38725089]
  • Munire Abudurexiti, Jun Xue, Xianzhe Li, Xiaofeng Zhang, Yongyi Qiu, Senjie Xiong, Guojing Liu, Sangui Yuan, Rongrui Tang. Curcumin/TGF-β1 siRNA loaded solid lipid nanoparticles alleviate cerebral injury after intracerebral hemorrhage by transnasal brain targeting. Colloids and surfaces. B, Biointerfaces. 2024 May; 237(?):113857. doi: 10.1016/j.colsurfb.2024.113857. [PMID: 38552289]
  • Pablo Vinicius Novakoski, Maksuel Gatto de Vitt, Vitor Luiz Molosse, Ana Carolina Hadlich Xavier, Roger Wagner, Bruna Klein, Carine Freitas Milarch, Luiz Eduardo Leonardi, Gilberto Vilmar Kozloski, Marcelo Vedovatto, Aleksandro S da Silva. The addition of curcumin to the diet of post-weaning dairy calves: effects on ruminal fermentation, immunological, and oxidative responses. Tropical animal health and production. 2024 Apr; 56(4):142. doi: 10.1007/s11250-024-03993-1. [PMID: 38662082]
  • Jiankun Cui, Xin Wang, Lingling Dong, Qinwen Wang. Curcumin reduces myocardial ischemia-reperfusion injury, by increasing endogenous H2S levels and further modulating m6A. Molecular biology reports. 2024 Apr; 51(1):558. doi: 10.1007/s11033-024-09478-6. [PMID: 38643323]
  • Jayoung Chae, Yonghyun Choi, Joohye Hong, Namju Kim, Jiwon Kim, Hee-Young Lee, Jonghoon Choi. Anticancer and Antibacterial Properties of Curcumin-Loaded Mannosylated Solid Lipid Nanoparticles for the Treatment of Lung Diseases. ACS applied bio materials. 2024 Apr; 7(4):2175-2185. doi: 10.1021/acsabm.3c01145. [PMID: 38478917]
  • Tiziana Latronico, Tania Petraglia, Carmela Sileo, Domenico Bilancia, Rocco Rossano, Grazia Maria Liuzzi. Inhibition of MMP-2 and MMP-9 by Dietary Antioxidants in THP-1 Macrophages and Sera from Patients with Breast Cancer. Molecules (Basel, Switzerland). 2024 Apr; 29(8):. doi: 10.3390/molecules29081718. [PMID: 38675538]
  • Yiping Zhang, Jun Xie. Induction of ferroptosis by natural phenols: A promising strategy for cancer therapy. Phytotherapy research : PTR. 2024 Apr; 38(4):2041-2076. doi: 10.1002/ptr.8149. [PMID: 38391022]
  • Raquel F S Gonçalves, Jean-Michel Fernandes, Joana T Martins, Jorge M Vieira, Cristiano S Abreu, José R Gomes, António A Vicente, Ana C Pinheiro. Incorporation of curcumin-loaded solid lipid nanoparticles into yogurt: Tribo-rheological properties and dynamic in vitro digestion. Food research international (Ottawa, Ont.). 2024 Apr; 181(?):114112. doi: 10.1016/j.foodres.2024.114112. [PMID: 38448111]
  • Umay Sevgi Vardar, Johannes H Bitter, Constantinos V Nikiforidis. The mechanism of encapsulating curcumin into oleosomes (Lipid Droplets). Colloids and surfaces. B, Biointerfaces. 2024 Apr; 236(?):113819. doi: 10.1016/j.colsurfb.2024.113819. [PMID: 38428208]
  • Niloofar Nasiri-Foomani, Mehdi Ebadi, Saeed Hassani, Saeed Zeinoaldini, Aria Saedi, Firooz Samadi. Preparation, characterization, and ex-vivo evaluation of curcumin-loaded niosomal nanoparticles on the equine sperm quality during cooled storage. International journal of biological macromolecules. 2024 Apr; 264(Pt 1):130620. doi: 10.1016/j.ijbiomac.2024.130620. [PMID: 38447838]
  • Samiksha Rele, Chanchal Kiran Thakur, Fatima Khan, Budhadev Baral, Vaishali Saini, Chandrabose Karthikeyan, N S Hari Narayana Moorthy, Hem Chandra Jha. Curcumin coating: a novel solution to mitigate inherent carbon nanotube toxicity. Journal of materials science. Materials in medicine. 2024 Mar; 35(1):24. doi: 10.1007/s10856-024-06789-9. [PMID: 38526738]
  • Sajid Ali, Jonas K Koehler, Luís Silva, Lars Gedda, Ulrich Massing, Katarina Edwards. Dual centrifugation as a novel and efficient method for the preparation of lipodisks. International journal of pharmaceutics. 2024 Mar; 653(?):123894. doi: 10.1016/j.ijpharm.2024.123894. [PMID: 38350501]
  • Honglei Guo, Tianyu Lan, Xin Lu, Kedui Geng, Xiangchun Shen, Huijuan Mao, Qianqian Guo. ROS-responsive curcumin-encapsulated nanoparticles for AKI therapy via promoting lipid degradation in renal tubules. Journal of materials chemistry. B. 2024 Mar; 12(12):3063-3078. doi: 10.1039/d3tb02318d. [PMID: 38441636]
  • Selvanathan Mj Vinola, Sekar Mahalaxmi. Characterisation and evaluation of physical properties of AH-Plus sealer with and without the incorporation of petasin, pachymic acid, curcumin and shilajit-an invitro study. BMC oral health. 2024 Mar; 24(1):352. doi: 10.1186/s12903-024-04108-w. [PMID: 38504287]
  • Meghana N Kumar, Sreeram Peringattu Kalarikkal, Yashaswini Jayaram, Janakiraman Narayanan, Gopinath M Sundaram. Protocol to produce plant-based hybrid nanovesicles from fresh turmeric and pepper using polyethylene glycol. STAR protocols. 2024 Mar; 5(1):102924. doi: 10.1016/j.xpro.2024.102924. [PMID: 38430518]
  • Jehad Zuhair Tayyeb, Madhu Priya, Ajay Guru, Meenakshi Sundaram Kishore Kumar, Jayant Giri, Akash Garg, Rutvi Agrawal, Khairiyah Binti Mat, Jesu Arockiaraj. Multifunctional curcumin mediated zinc oxide nanoparticle enhancing biofilm inhibition and targeting apoptotic specific pathway in oral squamous carcinoma cells. Molecular biology reports. 2024 Mar; 51(1):423. doi: 10.1007/s11033-024-09407-7. [PMID: 38489102]
  • Yixuan Liu, Feng Lin, Cheng Wu, Wanguo Liu, Hao Wang, Chunsheng Xiao, Xuesi Chen. In Situ Reaction-Generated Aldehyde-Scavenging Polypeptides-Curcumin Conjugate Nanoassemblies for Combined Treatment of Spinal Cord Injury. ACS nano. 2024 Mar; 18(10):7346-7362. doi: 10.1021/acsnano.3c08662. [PMID: 38416031]
  • Rhulani Makhuvele, Kenn Foubert, Nina Hermans, Luc Pieters, Luc Verschaeve, Esameldin Elgorashi. Hepatoprotective effects of leaf extract of Annona senegalensis against aflatoxin B1 toxicity in rats. The Onderstepoort journal of veterinary research. 2024 Mar; 91(1):e1-e6. doi: 10.4102/ojvr.v91i1.2133. [PMID: 38572889]
  • Dong-Oh Moon. Curcumin in Cancer and Inflammation: An In-Depth Exploration of Molecular Interactions, Therapeutic Potentials, and the Role in Disease Management. International journal of molecular sciences. 2024 Mar; 25(5):. doi: 10.3390/ijms25052911. [PMID: 38474160]
  • Wei Xin, Yong Zhang. Curcumin activates the JNK signaling pathway to promote ferroptosis in colon cancer cells. Chemical biology & drug design. 2024 03; 103(3):e14468. doi: 10.1111/cbdd.14468. [PMID: 38443754]
  • Armin Ebrahimzadeh, Shokouh Mohseni, Mohammad Safargar, Abbas Mohtashamian, Sara Niknam, Mohammadreza Bakhoda, Sanaz Afshari, Amirhossein Jafari, Anahita Ebrahimzadeh, Sara Fooladshekan, Alireza Mohtashami, Gordon A Ferns, Siavash Babajafari, Zahra Sohrabi. Curcumin effects on glycaemic indices, lipid profile, blood pressure, inflammatory markers and anthropometric measurements of non-alcoholic fatty liver disease patients: A systematic review and meta-analysis of randomized clinical trials. Complementary therapies in medicine. 2024 Mar; 80(?):103025. doi: 10.1016/j.ctim.2024.103025. [PMID: 38232906]
  • Jian Xu, Dong Zhang, Yibo Ma, Hui Du, Yi Wang, Wenping Luo, Ruxing Wang, Fu Yi. ROS in diabetic atria regulate SK2 degradation by Atrogin-1 through the NF-κB signaling pathway. The Journal of biological chemistry. 2024 Mar; 300(3):105735. doi: 10.1016/j.jbc.2024.105735. [PMID: 38336298]
  • Wenjuan Wang, Rui Sun, Suping Ji, Qiang Xia. Effects of κ-carrageenan on the emulsifying ability and encapsulation properties of pea protein isolate-grape seed oil emulsions. Food chemistry. 2024 Mar; 435(?):137561. doi: 10.1016/j.foodchem.2023.137561. [PMID: 37776649]
  • Robert A Oxley, Daniel J Peart. The effect of curcumin supplementation on functional strength outcomes and markers of exercise-induced muscle damage: A systematic review and meta-analysis. Nutrition and health. 2024 Mar; 30(1):77-92. doi: 10.1177/02601060231186439. [PMID: 37408367]
  • Jinlong Zhao, Guihong Liang, Guanghui Zhou, Kunhao Hong, Weiyi Yang, Jun Liu, Lingfeng Zeng. Efficacy and safety of curcumin therapy for knee osteoarthritis: A Bayesian network meta-analysis. Journal of ethnopharmacology. 2024 Mar; 321(?):117493. doi: 10.1016/j.jep.2023.117493. [PMID: 38036015]
  • Xianmou Fan, Jun Huang, Wanjun Zhang, Zhihong Su, Jin Li, Zeyong Wu, Peihua Zhang. A Multifunctional, Tough, Stretchable, and Transparent Curcumin Hydrogel with Potent Antimicrobial, Antioxidative, Anti-inflammatory, and Angiogenesis Capabilities for Diabetic Wound Healing. ACS applied materials & interfaces. 2024 Feb; 16(8):9749-9767. doi: 10.1021/acsami.3c16837. [PMID: 38359334]
  • Suryani Dyah Astuti, Amiliyatul Mawaddah, Idha Kusumawati, Amalia Fitriana Mahmud, Aulia Muhammad Taufiq Nasution, Bambang Purwanto, Yunus Susilo, Ahmad Khalil Yaqubi, Ardiansyah Syahrom. Fluorescent microscopy evaluation of diode laser effect on the penetration depth of turmeric (Curcuma longa) extract cream on skin tissues of Wistar rats. Lasers in medical science. 2024 Feb; 39(1):79. doi: 10.1007/s10103-024-04020-3. [PMID: 38393433]
  • Marakiya T Moetlediwa, Babalwa U Jack, Sithandiwe E Mazibuko-Mbeje, Carmen Pheiffer, Salam J J Titinchi, Elliasu Y Salifu, Pritika Ramharack. Evaluating the Therapeutic Potential of Curcumin and Synthetic Derivatives: A Computational Approach to Anti-Obesity Treatments. International journal of molecular sciences. 2024 Feb; 25(5):. doi: 10.3390/ijms25052603. [PMID: 38473849]
  • Natalia Rosiak, Ewa Garbiec, Waldemar Bednarski, Robert Skibiński, Kornelia Lewandowska, Aleksandra Bazan-Woźniak, Robert Pietrzak, Judyta Cielecka-Piontek, Przemysław Zalewski. How Does Radiation Affect Curcumin Raw Material?. International journal of molecular sciences. 2024 Feb; 25(5):. doi: 10.3390/ijms25052524. [PMID: 38473770]
  • Jingwen Xie, Yingxin Zhao, Xingyu Liu, Lingling Li, Lei Yu, Mengxuan Wang, Qian Li. The effect and mechanism of novel methoxy curcumin analogs based on network pharmacology. Medicine. 2024 Feb; 103(7):e36483. doi: 10.1097/md.0000000000036483. [PMID: 38363917]
  • Yajun Wang, Di Zhou, Xueni Zhang, Mengli Qing, Xiaohong Li, Yixian Chou, Gang Chen, Ning Li. Curcumin promotes renewal of intestinal epithelium by miR-195-3p. Journal of ethnopharmacology. 2024 Feb; 320(?):117413. doi: 10.1016/j.jep.2023.117413. [PMID: 37972911]
  • Zhe Li, Xiaosui Luo, Qiong Li, Zhengji Jin, Abid Naeem, Weifeng Zhu, Lihua Chen, Yi Feng, Liangshan Ming. The Fabrication, Drug Loading, and Release Behavior of Porous Mannitol. Molecules (Basel, Switzerland). 2024 Feb; 29(3):. doi: 10.3390/molecules29030715. [PMID: 38338458]
  • Deyi Zhou, Yuelin Xin, Baoguang Wu, Xiaofen Jiang, Xinling Wu, Pengfei Hou, Jiangtao Qi, Jinsong Zhang. Pickering emulsions stabilized by ternary complexes involving curcumin-modified zein and polysaccharides with different charge amounts for encapsulating β-carotene. Food chemistry. 2024 Feb; 433(?):137338. doi: 10.1016/j.foodchem.2023.137338. [PMID: 37683488]
  • Arruje Hameed, Waqas Maqsood, Amjad Hameed, Muhammad Abdul Qayyum, Toheed Ahmed, Tahir Farooq. Chitosan nanoparticles encapsulating curcumin counteract salt-mediated ionic toxicity in wheat seedlings: an ecofriendly and sustainable approach. Environmental science and pollution research international. 2024 Feb; 31(6):8917-8929. doi: 10.1007/s11356-023-31768-y. [PMID: 38182953]
  • Roghayeh Molani-Gol, Azadeh Dehghani, Maryam Rafraf. Effects of curcumin/turmeric supplementation on the liver enzymes, lipid profiles, glycemic index, and anthropometric indices in non-alcoholic fatty liver patients: An umbrella meta-analysis. Phytotherapy research : PTR. 2024 Feb; 38(2):539-555. doi: 10.1002/ptr.8051. [PMID: 37918958]
  • Xuanxuan Jiang, Haiyan Liu, Yanli You, Gaolong Zhong, Zhiyan Ruan, Jianzhao Liao, Hui Zhang, Jiaqiang Pan, Zhaoxin Tang, Lianmei Hu. Multi-omics reveals the protective effects of curcumin against AFB1-induced oxidative stress and inflammatory damage in duckling intestines. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2024 Feb; 276(?):109815. doi: 10.1016/j.cbpc.2023.109815. [PMID: 38061615]
  • Jinlian Gu, Chang Yan, Shun Yin, Hao Wu, Chi Liu, Ao Xue, Xia Lei, Ning Zhang, Fang Geng. Erythrocyte membrane-coated nanocarriers modified by TGN for Alzheimer's disease. Journal of controlled release : official journal of the Controlled Release Society. 2024 Feb; 366(?):448-459. doi: 10.1016/j.jconrel.2023.12.030. [PMID: 38128884]
  • Drielly C M V Reis, Livia Alvarenga, Ludmila F M F Cardozo, Beatriz G Baptista, Susane Fanton, Bruna R Paiva, Marcelo Ribeiro-Alves, Rodrigo S Fortunato, Andressa L Vasconcelos, Lia S Nakao, Carmen Lucia Sanz, Andresa A Berretta, Maurilo Leite, Denise Mafra. Can curcumin supplementation break the vicious cycle of inflammation, oxidative stress, and uremia in patients undergoing peritoneal dialysis?. Clinical nutrition ESPEN. 2024 02; 59(?):96-106. doi: 10.1016/j.clnesp.2023.11.015. [PMID: 38220413]
  • Nubar Nuriyeva, Emir Enis Yurdgulu, Abdulmecit Albayrak, Huseyn Aliyev, Kubra Aliyeva, Beyzagul Erkayman, Yasin Bayir. Evaluation of the protective effects of curcumin-rich turmeric (Curcuma longa) extract against isotretinoin-induced liver damage in rats. Toxicology mechanisms and methods. 2024 Feb; 34(2):122-129. doi: 10.1080/15376516.2023.2260454. [PMID: 37771095]
  • Wenji Li, Fujun Wang, Xiaoxiang Wang, Wei Xu, Fangmin Liu, Rong Hu, Shanyi Li. Curcumin inhibits prostate cancer by upregulating miR-483-3p and inhibiting UBE2C. Journal of biochemical and molecular toxicology. 2024 Feb; 38(2):e23645. doi: 10.1002/jbt.23645. [PMID: 38348716]
  • Ying Huang, Fang-Yuan Liu, Jia-Tao Yang, Qian Zhao, Mei-Qi Zhu, Jing Wang, Shi-Yin Long, Qin-Hui Tuo, Cai-Ping Zhang, Li-Mei Lin, Duan-Fang Liao. Curcumin nicotinate increases LDL cholesterol uptake in hepatocytes through IDOL/LDL-R pathway regulation. European journal of pharmacology. 2024 Jan; 966(?):176352. doi: 10.1016/j.ejphar.2024.176352. [PMID: 38290567]
  • Karen L Posey. Curcumin and Resveratrol: Nutraceuticals with so Much Potential for Pseudoachondroplasia and Other ER-Stress Conditions. Biomolecules. 2024 Jan; 14(2):. doi: 10.3390/biom14020154. [PMID: 38397390]
  • Peng Ding, Xiaoyue Ding, Jingyu Li, Wei Guo, Oseweuba Valentine Okoro, Mahta Mirzaei, Yanfang Sun, Guohua Jiang, Amin Shavandi, Lei Nie. Facile preparation of self-healing hydrogels based on chitosan and PVA with the incorporation of curcumin-loaded micelles for wound dressings. Biomedical materials (Bristol, England). 2024 Jan; 19(2):. doi: 10.1088/1748-605x/ad1df9. [PMID: 38215487]
  • Kaushal Vyas, Supraja Prabaker, Dhamodharan Prabhu, Meenakumari Sakthivelu, Sundararaj Rajamanikandan, Palaniyandi Velusamy, Chia-Hung Su, Subash C B Gopinath, Raman Pachaiappan. Study of an inhibitory effect of plant polyphenolic compounds against digestive enzymes using bench-working experimental evidence predicted by molecular docking and dynamics. International journal of biological macromolecules. 2024 Jan; 259(Pt 1):129222. doi: 10.1016/j.ijbiomac.2024.129222. [PMID: 38185307]
  • Ibrahim Taha Radwan, Nirvina Abdel Raouf Ghazawy, Abeer Mousa Alkhaibari, Hattan S Gattan, Mohammed H Alruhaili, Abdelfattah Selim, Mostafa E Salem, Eman Alaaeldin AbdelFattah, Heba M Hamama. Nanostructure Lipid Carrier of Curcumin Co-Delivered with Linalool and Geraniol Monoterpenes as Acetylcholinesterase Inhibitor of Culex pipiens. Molecules (Basel, Switzerland). 2024 Jan; 29(1):. doi: 10.3390/molecules29010271. [PMID: 38202854]
  • Wei Xu, Yu Shen. Curcumin affects apoptosis of colorectal cancer cells through ATF6-mediated endoplasmic reticulum stress. Chemical biology & drug design. 2024 Jan; 103(1):e14433. doi: 10.1111/cbdd.14433. [PMID: 38230779]
  • Xiankuan Li, Weisan Chen, Jiali Ren, Xinchen Gao, Ying Zhao, Tianbao Song, Kun Fu, Yanchao Zheng, Jinlong Yang. Effects of curcumin on non-alcoholic fatty liver disease: A scientific metrogy study. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155241. doi: 10.1016/j.phymed.2023.155241. [PMID: 38128395]
  • Guangyi Gao, Wenhang Zhou, Xuan Jiang, Jun Ma. Bovine serum albumin and folic acid-modified aurum nanoparticles loaded with paclitaxel and curcumin enhance radiotherapy sensitization for esophageal cancer. International journal of radiation biology. 2024; 100(3):411-419. doi: 10.1080/09553002.2023.2281524. [PMID: 37934908]
  • Beyza Sümeyye Aydin, Ali Asram Sagiroglu, Dilek Ozturk Civelek, Mustafa Gokce, Fatemeh Bahadori. Development of Curcumin and Turmerone Loaded Solid Lipid Nanoparticle for Topical Delivery: Optimization, Characterization and Skin Irritation Evaluation with 3D Tissue Model. International journal of nanomedicine. 2024; 19(?):1951-1966. doi: 10.2147/ijn.s453347. [PMID: 38435752]
  • Fatemeh Mobinhosseini, Mahsa Salehirad, A Wallace Hayes, Majid Motaghinejad, Malak Hekmati, Sepideh Safari, Mina Gholami. Curcumin-ZnO conjugated nanoparticles confer neuroprotection against ketamine-induced neurotoxicity. Journal of biochemical and molecular toxicology. 2024 Jan; 38(1):e23611. doi: 10.1002/jbt.23611. [PMID: 38084605]
  • Haohang Ruan, Xuan Zeng, Silan Shen. Mechanism of Curcumin Inhibiting NLRP3 Inflammatory Body and Improving Atherosclerotic Endothelial Cell Injury. Discovery medicine. 2024 Jan; 36(180):121-128. doi: 10.24976/discov.med.202436180.11. [PMID: 38273752]
  • Diptimayee Das, Kanchan M, Abhijit Mitra, Mohamed Y Zaky, Surajit Pathak, Antara Banerjee. A Review on the Efficacy of Plant-derived Bio-active Compounds Curcumin and Aged Garlic Extract in Modulating Cancer and Age-related Diseases. Current reviews in clinical and experimental pharmacology. 2024; 19(2):146-162. doi: 10.2174/2772432819666230504093227. [PMID: 37150987]
  • Seyedeh Mehrnaz Aghili, Maryam Sahebari, Masoumeh Salari, Parisa Noorabadi. Efficacy of Herbal Medicine in Hand Osteoarthritis: A Narrative Review. Current rheumatology reviews. 2024; 20(1):39-45. doi: 10.2174/1573397119666230907112401. [PMID: 37691222]
  • Shahzad Farooq, Muhammad Ijaz Ahmad, Usman Ali, Hui Zhang. Fabrication of curcumin-loaded oleogels using camellia oil bodies and gum arabic/chitosan coatings for controlled release applications. International journal of biological macromolecules. 2024 Jan; 254(Pt 1):127758. doi: 10.1016/j.ijbiomac.2023.127758. [PMID: 38287596]
  • Yuanyuan Wang, Ruibo Guo, Ming Zou, Lingling Jiang, Liang Kong, Sen Zhao, Xuan Zhang, Wei Wang, Baoli Xu. Combined ROS Sensitive Folate Receptor Targeted Micellar Formulations of Curcumin Effective Against Rheumatoid Arthritis in Rat Model. International journal of nanomedicine. 2024; 19(?):4217-4234. doi: 10.2147/ijn.s458957. [PMID: 38766660]
  • Yun-Hang Chu, Bing-Yao Pang, Ming Yang, Qi Meng, Yan Leng. The intervention of curcumin on rodent models of hepatic fibrosis: A systematic review and meta-analysis. PloS one. 2024; 19(5):e0304176. doi: 10.1371/journal.pone.0304176. [PMID: 38781262]
  • Meriam N N Rezk, Sabreen Mahmoud Ahmed, Shereen S Gaber, Mostafa M Mohammed, Nada A Yousri, Nermeen N Welson. Curcumin protects against lamotrigine-induced chronic ovarian and uterine toxicity in rats by regulating PPAR-γ and ROS production. Journal of biochemical and molecular toxicology. 2024 Jan; 38(1):e23599. doi: 10.1002/jbt.23599. [PMID: 38050455]
  • Chunkun Yang, Qinwei Zhu, Yanbo Chen, Kui Ji, Shuanghong Li, Qian Wu, Qingquan Pan, Jun Li. Review of the Protective Mechanism of Curcumin on Cardiovascular Disease. Drug design, development and therapy. 2024; 18(?):165-192. doi: 10.2147/dddt.s445555. [PMID: 38312990]
  • Huandong Zhao, Ruimin Ding, Jiarui Han. Curcumin Enhances the Anti-Cancer Efficacy of CDK4/6 Inhibitors in Prostate Cancer. Archivos espanoles de urologia. 2024 Jan; 77(1):57-66. doi: 10.56434/j.arch.esp.urol.20247701.8. [PMID: 38374014]
  • Qi Meng, Mengmeng Xu, Lei Chen, Sha Xu, Jinwei Li, Youran Li, Liuping Fan, Guiyang Shi, Zhongyang Ding. Emulsion for stabilizing β-carotene and curcumin prepared directly using a continuous phase of polysaccharide-rich Schizophyllum commune fermentation broth. International journal of biological macromolecules. 2024 Jan; 254(Pt 1):127730. doi: 10.1016/j.ijbiomac.2023.127730. [PMID: 38287588]
  • Chujing Wang, Wenni Tian, Zengliu Song, Qun Wang, Yong Cao, Jie Xiao. Effects of solid lipid ratio in curcumin loaded emulsions on its gastrointestinal fate: Colloidal stability and mucus absorption efficiency. Food research international (Ottawa, Ont.). 2024 Jan; 175(?):113631. doi: 10.1016/j.foodres.2023.113631. [PMID: 38128976]
  • Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan. Curcumin improves the egg quality, antioxidant activity, and intestinal microbiota of quails during the late laying period. Poultry science. 2024 Jan; 103(1):103233. doi: 10.1016/j.psj.2023.103233. [PMID: 37980738]
  • Manni Rohilla, Rishabh, Seema Bansal, Anjali Garg, Sachin Dhiman, Sanchit Dhankhar, Monika Saini, Samrat Chauhan, Nawal Alsubaie, Gaber El-Saber Batiha, Nisreen Khalid Aref Albezrah, Thakur Gurjeet Singh. Discussing pathologic mechanisms of Diabetic retinopathy & therapeutic potentials of curcumin and β-glucogallin in the management of Diabetic retinopathy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Dec; 169(?):115881. doi: 10.1016/j.biopha.2023.115881. [PMID: 37989030]
  • Seyedeh Niloofar Salimbahrami, Azade Ghorbani-HasanSaraei, Hasan Tahermansouri, Seyed-Ahmad Shahidi. Synthesis, optimization via response surface methodology, and structural properties of carboxymethylcellulose/curcumin/graphene oxide biocomposite films/coatings for the shelf-life extension of shrimp. International journal of biological macromolecules. 2023 Dec; 253(Pt 2):126724. doi: 10.1016/j.ijbiomac.2023.126724. [PMID: 37673155]
  • Pranglada Jearjaroen, Phakkawat Thangwong, Chainarong Tocharus, Waraluck Chaichompoo, Apichart Suksamrarn, Jiraporn Tocharus. Hexahydrocurcumin attenuated demyelination and improved cognitive impairment in chronic cerebral hypoperfusion rats. Inflammopharmacology. 2023 Dec; ?(?):. doi: 10.1007/s10787-023-01406-7. [PMID: 38153537]
  • Abdullah Khalid Alsulaim, Turki Hussain Almutaz, Abdulaziz Ahmed Albati, Arshad Husain Rahmani. Therapeutic Potential of Curcumin, a Bioactive Compound of Turmeric, in Prevention of Streptozotocin-Induced Diabetes through the Modulation of Oxidative Stress and Inflammation. Molecules (Basel, Switzerland). 2023 Dec; 29(1):. doi: 10.3390/molecules29010128. [PMID: 38202711]
  • Tariful Islam, Shane Scoggin, Xiaoxia Gong, Masoud Zabet-Moghaddam, Nishan S Kalupahana, Naima Moustaid-Moussa. Anti-Inflammatory Mechanisms of Curcumin and Its Metabolites in White Adipose Tissue and Cultured Adipocytes. Nutrients. 2023 Dec; 16(1):. doi: 10.3390/nu16010070. [PMID: 38201900]
  • Gabriel Nicolo A De Guzman, Jeff Ryan S Magalong, Jose Paolo O Bantang, Julius L Leaño. Enhanced Photoluminescence of Curcuma longa Extracts via Chitosan-Mediated Energy Transfer for Textile Authentication Applications. Journal of visualized experiments : JoVE. 2023 Dec; ?(202):. doi: 10.3791/66035. [PMID: 38189491]
  • Jan Schulze, Lisa Schöne, Abdallah M Ayoub, Damiano Librizzi, Muhammad Umair Amin, Konrad Engelhardt, Behrooz H Yousefi, Lena Bender, Jens Schaefer, Eduard Preis, Michaela Schulz-Siegmund, Christian Wölk, Udo Bakowsky. Modern Photodynamic Glioblastoma Therapy Using Curcumin- or Parietin-Loaded Lipid Nanoparticles in a CAM Model Study. ACS applied bio materials. 2023 Dec; 6(12):5502-5514. doi: 10.1021/acsabm.3c00695. [PMID: 38016693]
  • Rodrigo C Silva, Hilde H Buzzá, Eli S A Ducas, Kleber T Oliveira, Vanderlei S Bagnato, Guilherme R L Souza, Luciane M Almeida, Pablo J Gonçalves. Synergic vascular photodynamic activity by methylene blue-curcumin supramolecular assembly. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2023 Dec; 303(?):123281. doi: 10.1016/j.saa.2023.123281. [PMID: 37625276]
  • Kosar Boshagh, Fariborz Khorvash, Amirhossein Sahebkar, Muhammed Majeed, Nimah Bahreini, Gholamreza Askari, Mohammad Bagherniya. The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial. Nutrition journal. 2023 Dec; 22(1):69. doi: 10.1186/s12937-023-00905-1. [PMID: 38082237]
  • Nana Zheng, Yuanyuan Xie, Meng Zhou, Yuzhen Liu, Haoxiang Xu, Rong Zeng, Chunping Wan, Min Li. Utilizing the Photodynamic Properties of Curcumin to Disrupt Biofilms in Cutibacterium acnes: A Promising Approach for Treating Acne. Photodiagnosis and photodynamic therapy. 2023 Dec; ?(?):103928. doi: 10.1016/j.pdpdt.2023.103928. [PMID: 38070633]
  • Alessandro Maugeri, Caterina Russo, Giuseppe Tancredi Patanè, Davide Barreca, Giuseppina Mandalari, Michele Navarra. The Inhibition of Mitogen-Activated Protein Kinases (MAPKs) and NF-κB Underlies the Neuroprotective Capacity of a Cinnamon/Curcumin/Turmeric Spice Blend in Aβ-Exposed THP-1 Cells. Molecules (Basel, Switzerland). 2023 Dec; 28(24):. doi: 10.3390/molecules28247949. [PMID: 38138438]