2-Furoic acid (BioDeep_00000002867)

 

Secondary id: BioDeep_00000405311, BioDeep_00000864035

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


furan-2-carboxylic acid

化学式: C5H4O3 (112.016)
中文名称: 2-糠酸, 糠酸
谱图信息: 最多检出来源 Homo sapiens(plant) 15.78%

Reviewed

Last reviewed on 2024-07-10.

Cite this Page

2-Furoic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/2-furoic_acid (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000002867). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=COC(=C1)C(=O)O
InChI: InChI=1S/C5H4O3/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)

描述信息

Furoic acid is a metabolite that appears in the urine of workers occupationally exposed to furfural and is a marker of exposure to this compound. Furfural is a heterocyclic aldehyde that is commonly used as a solvent in industry. It is readily absorbed into the body via the lungs and has significant skin absorption. Furfural is an irritant of the eyes, mucous membranes, and skin and is a central nervous system depressant. Furfural as a confirmed animal carcinogen with unknown relevance to humans (It has been suggested that is a substance that produces hepatic cirrhosis). Once in the body, furfural is metabolized rapidly via oxidation to the metabolite furoic acid, which is then conjugated with glycine and excreted in the urine in both free and conjugated forms. (PMID: 3751566, 4630229, 12587683). 2-Furoic acid is a biomarker for the consumption of beer.

2-Furancarboxylic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=88-14-2 (retrieved 2024-07-10) (CAS RN: 88-14-2). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].

同义名列表

44 个代谢物同义名

2-Furoic acid, sodium salt; alpha-Furancarboxylic acid; beta-Furancarboxylic acid; Furan-2-carboxylic acid; alpha-Furancarboxylate; Α-furancarboxylic acid; b-Furancarboxylic acid; 2-Furancarboxylic acid; a-Furancarboxylic acid; beta-Furancarboxylate; Furancarboxylic acid; Furan-2-carbonsaeure; Furan-2-carboxylate; Α-furancarboxylate; Furan-3-carboxylic; b-Furancarboxylate; 2-Furancarboxylate; a-Furancarboxylate; alpha-Furoic acid; Furan-2-ylacetate; beta-Furoic acid; Acide 2-furoique; Furancarboxylate; Acido 2-furoico; 2-Furanoic acid; Pyromucic acid; 2-Carboxyfuran; Α-furoic acid; a-Furoic acid; alpha-Furoate; 2-FUROIC ACID; b-Furoic acid; beta-Furoate; 2-Furanoate; furoic acid; Pyromucate; a-Furoate; Α-furoate; 2-Furoate; b-Furoate; Furoate; 2-Furoic acid; 2-Furoic acid; 2-Furoate



数据库引用编号

26 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

86 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ACLY, ALB, BGLAP, DAO, FDPS, HPGDS, NQO1, NR3C1, PFDN5, PLA2G12A, TYR, VEGFA
Peripheral membrane protein 3 CTSK, DAO, LPL
Nucleus 5 ALB, NQO1, NR3C1, PFDN5, VEGFA
cytosol 10 ACLY, ALB, B2M, DAO, FDPS, HPGDS, LIPE, NQO1, NR3C1, PFDN5
dendrite 2 BGLAP, NQO1
centrosome 2 ALB, NR3C1
nucleoplasm 5 ACLY, CTSK, FDPS, HPGDS, NR3C1
Cell membrane 6 B2M, CTSK, DAO, LIPE, LPL, TNF
Early endosome membrane 1 B2M
Synapse 2 NQO1, NR3C1
cell surface 4 B2M, LPL, TNF, VEGFA
Golgi apparatus 3 ALB, B2M, VEGFA
Golgi membrane 1 B2M
lysosomal membrane 1 B2M
neuronal cell body 2 NQO1, TNF
Cytoplasm, cytosol 4 ACLY, DAO, LIPE, NQO1
Lysosome 2 CTSK, TYR
plasma membrane 5 B2M, CTSK, DAO, LPL, TNF
presynaptic active zone 1 DAO
Membrane 7 ACLY, B2M, FDPS, LIPE, NQO1, NR3C1, VEGFA
apical plasma membrane 1 CTSK
caveola 1 LIPE
extracellular exosome 5 ACLY, ALB, B2M, DAO, TOR1B
endoplasmic reticulum 4 ALB, B2M, TOR1B, VEGFA
extracellular space 10 ALB, B2M, BGLAP, CTSK, DAO, IL2, LPL, PTH, TNF, VEGFA
lysosomal lumen 1 CTSK
perinuclear region of cytoplasm 1 TYR
adherens junction 1 VEGFA
bicellular tight junction 1 DAO
mitochondrion 1 NR3C1
protein-containing complex 2 ALB, NR3C1
intracellular membrane-bounded organelle 3 CTSK, HPGDS, TYR
Single-pass type I membrane protein 1 TYR
Secreted 9 ALB, B2M, BGLAP, CTSK, DAO, IL2, LPL, PLA2G12A, VEGFA
extracellular region 12 ACLY, ALB, B2M, BGLAP, CTSK, DAO, IL2, LPL, PLA2G12A, PTH, TNF, VEGFA
mitochondrial matrix 2 FDPS, NR3C1
Extracellular side 3 CTSK, DAO, LPL
anchoring junction 1 ALB
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NR3C1
Nucleus membrane 1 TOR1B
nuclear membrane 1 TOR1B
external side of plasma membrane 3 B2M, CTSK, TNF
Secreted, extracellular space, extracellular matrix 2 LPL, VEGFA
chylomicron 1 LPL
very-low-density lipoprotein particle 1 LPL
perikaryon 1 BGLAP
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 BGLAP
Apical cell membrane 1 CTSK
Membrane raft 1 TNF
Cytoplasm, cytoskeleton, spindle 1 NR3C1
focal adhesion 1 B2M
spindle 1 NR3C1
extracellular matrix 1 VEGFA
Peroxisome 2 DAO, FDPS
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
secretory granule 1 VEGFA
nuclear speck 1 NR3C1
ciliary basal body 1 ALB
chromatin 1 NR3C1
Late endosome membrane 1 B2M
cell projection 1 DAO
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 B2M
Chromosome 1 NR3C1
centriole 1 ALB
Secreted, extracellular space 1 DAO
spindle pole 1 ALB
blood microparticle 1 ALB
nuclear envelope 1 TOR1B
Recycling endosome membrane 1 B2M
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Nucleus, nucleoplasm 1 NR3C1
Melanosome 1 TYR
intermediate filament cytoskeleton 1 PFDN5
ficolin-1-rich granule lumen 1 ACLY
HFE-transferrin receptor complex 1 B2M
Golgi lumen 1 BGLAP
endoplasmic reticulum lumen 4 ALB, B2M, BGLAP, TOR1B
platelet alpha granule lumen 2 ALB, VEGFA
specific granule lumen 2 B2M, DAO
tertiary granule lumen 1 B2M
azurophil granule lumen 1 ACLY
ER to Golgi transport vesicle membrane 1 B2M
prefoldin complex 1 PFDN5
MHC class I peptide loading complex 1 B2M
[Isoform Alpha]: Cytoplasm 1 NR3C1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
MHC class I protein complex 1 B2M
MHC class II protein complex 1 B2M
[Isoform Beta]: Nucleus 1 NR3C1
[Isoform Alpha-B]: Nucleus 1 NR3C1
catalytic complex 1 LPL
endolysosome lumen 1 CTSK
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
ciliary transition fiber 1 ALB
early endosome lumen 1 B2M
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


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