Uridine (BioDeep_00000000256)

 

Secondary id: BioDeep_00000229622, BioDeep_00000398753

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Chemicals and Drugs BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

化学式: C9H12N2O6 (244.0695332)
中文名称: 尿嘧啶核苷, 尿苷
谱图信息: 最多检出来源 Homo sapiens(blood) 0.01%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Uridine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/uridine (retrieved 2024-11-21) (BioDeep RN: BioDeep_00000000256). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)

描述信息

Uridine, also known as beta-uridine or 1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione, is a member of the class of compounds known as pyrimidine nucleosides. Pyrimidine nucleosides are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety. More specifically, uridine is a nucleoside consisting of uracil and D-ribose and a component of RNA. Uridine is soluble (in water) and a very weakly acidic compound (based on its pKa). Uridine can be synthesized from uracil. It is one of the five standard nucleosides which make up nucleic acids, the others being adenosine, thymidine, cytidine and guanosine. The five nucleosides are commonly abbreviated to their one-letter codes U, A, T, C and G respectively. Uridine is also a parent compound for other transformation products, including but not limited to, nikkomycin Z, 3-(enolpyruvyl)uridine 5-monophosphate, and 5-aminomethyl-2-thiouridine. Uridine can be found in most biofluids, including urine, breast milk, cerebrospinal fluid (CSF), and blood. Within the cell, uridine is primarily located in the mitochondria, in the nucleus and the lysosome. It can also be found in the extracellular space. As an essential nucleoside, uridine exists in all living species, ranging from bacteria to humans. In humans, uridine is involved in several metabolic disorders, some of which include dhydropyrimidinase deficiency, MNGIE (mitochondrial neurogastrointestinal encephalopathy), and beta-ureidopropionase deficiency. Moreover, uridine is found to be associated with Lesch-Nyhan syndrome, which is an inborn error of metabolism. Uridine is a nucleoside consisting of uracil and D-ribose and a component of RNA. Uridine plays a role in the glycolysis pathway of galactose. In humans there is no catabolic process to metabolize galactose. Therefore, galactose is converted to glucose and metabolized via the normal glucose metabolism pathways. More specifically, consumed galactose is converted into galactose 1-phosphate (Gal-1-P). This molecule is a substrate for the enzyme galactose-1-phosphate uridyl transferase which transfers a UDP molecule to the galactose molecule. The end result is UDP-galactose and glucose-1-phosphate. This process is continued to allow the proper glycolysis of galactose. Uridine is found in many foods (anything containing RNA) but is destroyed in the liver and gastrointestinal tract, and so no food, when consumed, has ever been reliably shown to elevate blood uridine levels. On the other hand, consumption of RNA-rich foods may lead to high levels of purines (adenine and guanosine) in blood. High levels of purines are known to increase uric acid production and may aggravate or lead to conditions such as gout.
Uridine is a ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a beta-N(1)-glycosidic bond. It has a role as a human metabolite, a fundamental metabolite and a drug metabolite. It is functionally related to a uracil.
Uridine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Uridine is a Pyrimidine Analog. The chemical classification of uridine is Pyrimidines, and Analogs/Derivatives.
Uridine is a natural product found in Ulva australis, Synechocystis, and other organisms with data available.
Uridine is a nucleoside consisting of uracil and D-ribose and a component of RNA. Uridine has been studied as a rescue agent to reduce the toxicities associated with 5-fluorouracil (5-FU), thereby allowing the administration of higher doses of 5-FU in chemotherapy regimens. (NCI04)
Uridine is a metabolite found in or produced by Saccharomyces cerevisiae.
A ribonucleoside in which RIBOSE is linked to URACIL.
Uridine is a molecule (known as a nucleoside) that is formed when uracil is attached to a ribose ring (also known as a ribofuranose) via a b-N1-glycosidic bond. ; Uridine is a molecule (known as a nucleoside) that is formed when uracil is attached to a ribose ring (also known as a ribofuranose) via a ?-N1-glycosidic bond. Uridine is found in many foods, some of which are celery leaves, canola, common hazelnut, and hickory nut.
A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a beta-N(1)-glycosidic bond.

[Spectral] Uridine (exact mass = 244.06954) and Adenosine (exact mass = 267.09675) and Glutathione (exact mass = 307.08381) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
[Spectral] Uridine (exact mass = 244.06954) and Glutathione (exact mass = 307.08381) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.

Uridine. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=58-96-8 (retrieved 2024-06-29) (CAS RN: 58-96-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.
Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.
Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.

同义名列表

71 个代谢物同义名

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; 1-((2R,3R,4S,5R)-tetrahydro-3,4-dihydroxy-5-(hydroxymethyl)furan-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-dihydropyrimi dine-2,4-dione; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; Uridine, United States Pharmacopeia (USP) Reference Standard; 1-beta-D-Ribofuranosyluracil, Uracil-1-beta-D-ribofuranoside; 1-beta-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione (Uridine); Uridine, powder, BioReagent, suitable for cell culture; beta-delta-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1; 1-beta-delta-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; .beta.-D-Ribofuranoside, 2,4(1H,3H)-pyrimidinedione-1; 1-.beta.-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; 1-.BETA.-D-RIBOFURANOSYLPYRIMIDINE-2,4(1H,3H)-DIONE; 1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione; b-D-Ribofuranoside 2,4(1H,3H)-pyrimidinedione-1; 1-b-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione; 1-Β-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione; 1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Uridine, Vetec(TM) reagent grade, 99\\%; 6B6FA3F8-70A2-44EA-B99C-D35D0A9237AA; ADENOSINE IMPURITY F (EP IMPURITY); ADENOSINE IMPURITY F [EP IMPURITY]; Uracil-1-.beta.-d-ribofuranoside; 1-beta-delta-Ribofuranosyluracil; Uracil, 1-beta-D-ribofuranosyl-; 1-.beta.-D-Ribofuranosyluracil; 1-beta-D-Ribofuranosyluracil; beta-D-ribofuranosyl-uridine; Uracil-1-A-D-ribofuranoside; Uridine, BioUltra, >=99\\%; 1-Β-D-ribofuranosyluracil; 1-A-D-Ribofuranosyluracil; 1-b-D-Ribofuranosyluracil; URIDINE [USP IMPURITY]; URIDINE (USP IMPURITY); URIDINE (USP-RS); URIDINE [USP-RS]; URIDINE [WHO-DD]; d-Ribosyl uracil; Uracil riboside; URIDINE [MART.]; URIDINE (MART.); UNII-WHI7HQ7H85; Uridine, >=99\\%; .beta.-Uridine; URIDINE [INCI]; URIDINE [MI]; Allo-Uridine; beta-Uridine; Allo Uridine; SMP1_000029; Uridine,(S); Allouridine; WHI7HQ7H85; b-Uridine; Β-uridine; AI3-52690; C9H12N2O6; d-uridine; Uridine; Uridin; 4jx9; 4pd6; 1af2; araU; Urd; u; Uridine; Uridine



数据库引用编号

63 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(17)

PlantCyc(5)

代谢反应

733 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(104)

WikiPathways(3)

Plant Reactome(0)

INOH(2)

PlantCyc(603)

COVID-19 Disease Map(2)

PathBank(19)

PharmGKB(0)

331 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Felipe Almeida Moreira, Jhon Fernando Berrío Escobar, Cristiano Giordani, Luciano Caseli. Exploring the physicochemical properties of the integration of Tristearoyl uridine in Langmuir monolayers: An approach to cell membrane modeling for prodrugs. Biophysical chemistry. 2024 Jul; 310(?):107256. doi: 10.1016/j.bpc.2024.107256. [PMID: 38728807]
  • Xiaoyue Yu, Jinqiu Sun, Yongjie Yang, Jianping Zhang, Yongliang Lu, Wei Tang. Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in Echinochloa crus-galli. Journal of agricultural and food chemistry. 2024 May; 72(20):11405-11414. doi: 10.1021/acs.jafc.4c02450. [PMID: 38717990]
  • Kjell Sergeant, Simon Goertz, Salma Halime, Hanna Tietgen, Hanna Heidt, Martina Minestrini, Cédric Jacquard, Stephanie Zimmer, Jenny Renaut. Exploration of the Diversity of Vicine and Convicine Derivatives in Faba Bean (Vicia faba L.) Cultivars: Insights from LC-MS/MS Spectra. Molecules (Basel, Switzerland). 2024 Feb; 29(5):. doi: 10.3390/molecules29051065. [PMID: 38474577]
  • Yi-Sheng Miao, Jia-Yue Wang, Rui-Rui Zhuang, Xiao-Kui Huo, Zi-Chang Yi, Xiao-Nan Sun, Zhen-Long Yu, Xiang-Ge Tian, Jing Ning, Lei Feng, Xiao-Chi Ma, Xia Lv. A high-affinity fluorescent probe for human uridine-disphosphate glucuronosyltransferase 1A9 function monitoring under environmental pollutant exposure. Journal of hazardous materials. 2024 Jan; 465(?):133439. doi: 10.1016/j.jhazmat.2024.133439. [PMID: 38218035]
  • Yingshan Ji, Jianqiang Sun, Jingxuan Xie, Wei Wu, Stella C Shuai, Qi Zhao, Wei Chen. m5UMCB: Prediction of RNA 5-methyluridine sites using multi-scale convolutional neural network with BiLSTM. Computers in biology and medicine. 2024 01; 168(?):107793. doi: 10.1016/j.compbiomed.2023.107793. [PMID: 38048661]
  • Natalia V Belosludtseva, Lubov L Pavlik, Irina B Mikheeva, Eugeny Yu Talanov, Dmitriy A Serov, Dmitriy A Khurtin, Konstantin N Belosludtsev, Galina D Mironova. Protective Effect of Uridine on Structural and Functional Rearrangements in Heart Mitochondria after a High-Dose Isoprenaline Exposure Modelling Stress-Induced Cardiomyopathy in Rats. International journal of molecular sciences. 2023 Dec; 24(24):. doi: 10.3390/ijms242417300. [PMID: 38139129]
  • Eva Ľuptáková, Armelle Vigouroux, Radka Končitíková, Martina Kopečná, David Zalabák, Ondřej Novák, Sara Salcedo Sarmiento, Sanja Ćavar Zeljković, David Jaroslav Kopečný, Klaus von Schwartzenberg, Miroslav Strnad, Lukáš Spíchal, Nuria De Diego, David Kopečný, Solange Moréra. Plant nucleoside N-ribohydrolases: riboside binding and role in nitrogen storage mobilization. The Plant journal : for cell and molecular biology. 2023 Dec; ?(?):. doi: 10.1111/tpj.16572. [PMID: 38044809]
  • Li Liu, Xue Feng, Jia-Lu Wang, Jia-Lei Chen, Meng-Meng Hou, Xiang-Yu Zhang, Kai-Yang Li, Xi-Wen Li, Shi-Lin Chen. [Comprehensive evaluation of Pinellia ternata germplasm resources based on phenotypic trait classification]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Dec; 48(24):6613-6623. doi: 10.19540/j.cnki.cjcmm.20230811.101. [PMID: 38212021]
  • Elena Lesch, Maike Simone Stempel, Vanessa Dressnandt, Bastian Oldenkott, Volker Knoop, Mareike Schallenberg-Rüdinger. Conservation of the moss RNA editing factor PPR78 despite the loss of its known C-to-U editing sites is explained by a hidden extra target. The Plant cell. 2023 Nov; ?(?):. doi: 10.1093/plcell/koad292. [PMID: 38000897]
  • Hee-Jin Song, Ji-Eun Kim, You-Jeong Jin, Yu-Jeong Roh, Ayun Seol, Tae-Ryeol Kim, Ki-Ho Park, Eun-Seo Park, Beum-Soo An, Seung-Yun Yang, Sungbaek Seo, Seong-Min Jo, Young-Suk Jung, Dae-Youn Hwang. Complement C3-Deficiency-Induced Constipation in FVB/N-C3em1Hlee/Korl Knockout Mice Was Significantly Relieved by Uridine and Liriope platyphylla L. Extracts. International journal of molecular sciences. 2023 Oct; 24(21):. doi: 10.3390/ijms242115757. [PMID: 37958740]
  • Yang Chen, Yanchen Guo, Hao Chang, Zebu Song, Zhi Wei, Zhao Huang, Zezhong Zheng, Guihong Zhang, Yankuo Sun. Brequinar inhibits African swine fever virus replication in vitro by activating ferroptosis. Virology journal. 2023 10; 20(1):242. doi: 10.1186/s12985-023-02204-x. [PMID: 37875895]
  • Nina I Uspalenko, Alexei A Mosentsov, Natalia V Khmil, Lyubov L Pavlik, Natalia V Belosludtseva, Natalia V Khunderyakova, Maria I Shigaeva, Vasilisa P Medvedeva, Anton E Malkov, Valentina F Kitchigina, Galina D Mironova. Uridine as a Regulator of Functional and Ultrastructural Changes in the Brain of Rats in a Model of 6-OHDA-Induced Parkinson's Disease. International journal of molecular sciences. 2023 Sep; 24(18):. doi: 10.3390/ijms241814304. [PMID: 37762607]
  • Matthew H Ward, Zeribe C Nwosu, Costas A Lyssiotis. Uridine: as sweet as sugar for some cells?. Cell research. 2023 Aug; ?(?):. doi: 10.1038/s41422-023-00860-w. [PMID: 37567975]
  • Zhefeng Wang, Yumei Zhang, Tiantian Zhou, Xin Wu. N-carbamoyl aspartate reduced body weight by stimulating the thermogenesis of iBAT. Biochemical and biophysical research communications. 2023 Jul; 665(?):152-158. doi: 10.1016/j.bbrc.2023.04.094. [PMID: 37163935]
  • Shangyu Gao, Yu Sun, Xiaoguang Chen, Changhua Zhu, Xiaoye Liu, Wenlei Wang, Lijun Gan, Yanwu Lu, Frank Schaarschmidt, Marco Herde, Claus-Peter Witte, Mingjia Chen. Pyrimidine catabolism is required to prevent the accumulation of 5-methyluridine in RNA. Nucleic acids research. 2023 Jun; ?(?):. doi: 10.1093/nar/gkad529. [PMID: 37334828]
  • Anne Caroline Joly, Shahinez Garcia, Jean-Michel Hily, Sandrine Koechler, Gérard Demangeat, Damien Garcia, Emmanuelle Vigne, Olivier Lemaire, Hélène Zuber, Dominique Gagliardi. An extensive survey of phytoviral RNA 3' uridylation identifies extreme variations and virus-specific patterns. Plant physiology. 2023 May; ?(?):. doi: 10.1093/plphys/kiad278. [PMID: 37177985]
  • Qing Yang, Yinchao Zhang, Xiaoling Qu, Fengyan Wu, Xiuchun Li, Min Ren, Ying Tong, Xiuming Wu, Aiguo Yang, Yong Chen, Shuai Chen. Genome-wide analysis of UDP-glycosyltransferases family and identification of UGT genes involved in abiotic stress and flavonol biosynthesis in Nicotiana tabacum. BMC plant biology. 2023 Apr; 23(1):204. doi: 10.1186/s12870-023-04208-9. [PMID: 37076827]
  • Volker Knoop. C-to-U and U-to-C: RNA editing in plant organelles and beyond. Journal of experimental botany. 2023 04; 74(7):2273-2294. doi: 10.1093/jxb/erac488. [PMID: 36527364]
  • Kaixia Niu, Pengpeng Bai, Junyang Zhang, Xinchi Feng, Feng Qiu. Cytidine Alleviates Dyslipidemia and Modulates the Gut Microbiota Composition in ob/ob Mice. Nutrients. 2023 Feb; 15(5):. doi: 10.3390/nu15051147. [PMID: 36904146]
  • Zhiyong Zhang, Xi Wang, Xiaoyang Zhang, Jiaheng Wu, Junhui Chen, Wenlong Li. Integrated LC-MS and network pharmacology methods to screen quantitative indicators in the Hippocampus histrix Kaup and method transfer. Journal of pharmaceutical and biomedical analysis. 2023 Feb; 228(?):115294. doi: 10.1016/j.jpba.2023.115294. [PMID: 36827860]
  • Rafael Itzhakov, Dmitry Tworowski, Noy Sadot, Tali Sayas, Elazar Fallik, Maya Kleiman, Elena Poverenov. Nucleoside-Based Cross-Linkers for Hydrogels with Tunable Properties. ACS applied materials & interfaces. 2023 Feb; 15(5):7359-7370. doi: 10.1021/acsami.2c19525. [PMID: 36701767]
  • Xiaoguang Chen, Sang-Hoon Kim, Sangkee Rhee, Claus-Peter Witte. A plastid nucleoside kinase is involved in inosine salvage and control of purine nucleotide biosynthesis. The Plant cell. 2023 Jan; 35(1):510-528. doi: 10.1093/plcell/koac320. [PMID: 36342213]
  • Martina Dvořáčková, Jiří Fajkus. Visualization of the Nucleolus Using 5' Ethynyl Uridine. Methods in molecular biology (Clifton, N.J.). 2023; 2672(?):377-385. doi: 10.1007/978-1-0716-3226-0_24. [PMID: 37335490]
  • Lianyu Zhou, Lu Jiao, Jiasheng Ju, Xuelan Ma. Effect of Sodium Selenite on the Metabolite Profile of Epichloë sp. Mycelia from Festuca sinensis in Solid Culture. Biological trace element research. 2022 Nov; 200(11):4865-4879. doi: 10.1007/s12011-021-03054-w. [PMID: 34973128]
  • Chuanlin Shi, Jie Zhang, Bingjin Wu, Rachel Jouni, Changxiu Yu, Blake C Meyers, Wanqi Liang, Qili Fei. Temperature-sensitive male sterility in rice determined by the roles of AGO1d in reproductive phasiRNA biogenesis and function. The New phytologist. 2022 11; 236(4):1529-1544. doi: 10.1111/nph.18446. [PMID: 36031742]
  • Dengtan Li, Jingwen Zhang, Chao Cheng, Kaixuan Hou, Xiaole Wang, Lusheng Zhu, Bing Li, Zhongkun Du, Jinhua Wang, Jun Wang. Effects of ecotoxicity of penoxsulam single and co-exposure with AgNPs on Eisenia fetida. Chemosphere. 2022 Nov; 307(Pt 4):136134. doi: 10.1016/j.chemosphere.2022.136134. [PMID: 36028129]
  • Tangqi Feng, Qian Peng, Lei Wang, Yuanli Xie, Kang Ouyang, Feile Li, Huazhong Zhou, Hongju Ma. Multiple resistance mechanisms to penoxsulam in Echinochloa crus-galli from China. Pesticide biochemistry and physiology. 2022 Oct; 187(?):105211. doi: 10.1016/j.pestbp.2022.105211. [PMID: 36127055]
  • Jiahao Cai, Xiaoyu Li, Shangbin Wu, Yang Tian, Yani Zhang, Zixin Wei, Zixiang Jin, Xiaojing Li, Xiong Chen, Wen-Xiong Chen. Assessing the causal association between human blood metabolites and the risk of epilepsy. Journal of translational medicine. 2022 09; 20(1):437. doi: 10.1186/s12967-022-03648-5. [PMID: 36180952]
  • Elena Lesch, Maximilian T Schilling, Sarah Brenner, Yingying Yang, Oliver J Gruss, Volker Knoop, Mareike Schallenberg-Rüdinger. Plant mitochondrial RNA editing factors can perform targeted C-to-U editing of nuclear transcripts in human cells. Nucleic acids research. 2022 09; 50(17):9966-9983. doi: 10.1093/nar/gkac752. [PMID: 36107771]
  • Xiaoyan Wang, Wenwen Kong, Yuan Wang, Jinhui Wang, Luyao Zhong, Kangwen Lao, Xianxin Dong, Dingyu Zhang, He Huang, Beixin Mo, Yu Yu, Guodong Ren. Uridylation and the SKI complex orchestrate the Calvin cycle of photosynthesis through RNA surveillance of TKL1 in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America. 2022 09; 119(38):e2205842119. doi: 10.1073/pnas.2205842119. [PMID: 36095196]
  • Ruijia He, Jing Qiao, Xiaoxia Wang, Wenlian Chen, Tong Yin. A new quantitative method for pseudouridine and uridine in human serum and its clinical application in acute myeloid leukemia. Journal of pharmaceutical and biomedical analysis. 2022 Sep; 219(?):114934. doi: 10.1016/j.jpba.2022.114934. [PMID: 35839582]
  • Mizuho Ichinose, Masuyo Kawabata, Yumi Akaiwa, Yasuka Shimajiri, Izumi Nakamura, Takayuki Tamai, Takahiro Nakamura, Yusuke Yagi, Bernard Gutmann. U-to-C RNA editing by synthetic PPR-DYW proteins in bacteria and human culture cells. Communications biology. 2022 09; 5(1):968. doi: 10.1038/s42003-022-03927-3. [PMID: 36109586]
  • Natalia V Belosludtseva, Vlada S Starinets, Irina B Mikheeva, Maxim N Belosludtsev, Mikhail V Dubinin, Galina D Mironova, Konstantin N Belosludtsev. Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in the C57BL/6 Mouse Model of High-Fat Diet-Streptozotocin-Induced Diabetes. International journal of molecular sciences. 2022 Sep; 23(18):. doi: 10.3390/ijms231810633. [PMID: 36142532]
  • Surabhi Bangarbale, Blythe D Shepard, Shivani Bansal, Meth M Jayatilake, Ryan Kurtz, Moshe Levi, Carolyn M Ecelbarger. Renal Metabolome in Obese Mice Treated with Empagliflozin Suggests a Reduction in Cellular Respiration. Biomolecules. 2022 08; 12(9):. doi: 10.3390/biom12091176. [PMID: 36139016]
  • Petja Rosenqvist, Janne J Mäkinen, Kaisa Palmu, Johanna Jokinen, Ranjit K Prajapati, Heidi J Korhonen, Pasi Virta, Georgiy A Belogurov, Mikko Metsä-Ketelä. The role of the maleimide ring system on the structure-activity relationship of showdomycin. European journal of medicinal chemistry. 2022 Jul; 237(?):114342. doi: 10.1016/j.ejmech.2022.114342. [PMID: 35439612]
  • Pengmian Feng, Wei Chen. iRNA-m5U: A sequence based predictor for identifying 5-methyluridine modification sites in Saccharomyces cerevisiae. Methods (San Diego, Calif.). 2022 07; 203(?):28-31. doi: 10.1016/j.ymeth.2021.04.013. [PMID: 33882361]
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