Aflatoxin B1 (BioDeep_00000002268)

 

Secondary id: BioDeep_00000399651, BioDeep_00001868891

human metabolite Endogenous blood metabolite Toxin natural product BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


(3S,7R)-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.0^{2,9}.0^{3,7}.0^{13,17}]nonadeca-1(12),2(9),4,10,13(17)-pentaene-16,18-dione

化学式: C17H12O6 (312.06338519999997)
中文名称: 黄曲霉素B1, 黄曲霉毒素B1
谱图信息: 最多检出来源 Homo sapiens(blood) 0.03%

Reviewed

Last reviewed on 2024-07-19.

Cite this Page

Aflatoxin B1. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/aflatoxin_b1 (retrieved 2024-11-21) (BioDeep RN: BioDeep_00000002268). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5C=COC5OC4=C1
InChI: InChI=1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3

描述信息

Aflatoxins are naturally occurring mycotoxins that are produced by many species of Aspergillus, a fungus. At least 13 different types of aflatoxin are produced in nature. Aflatoxin B1 is considered the most toxic and is produced by both Aspergillus flavus and Aspergillus parasiticus. The native habitat of Aspergillus is in soil, decaying vegetation, hay, and grains undergoing microbiological deterioration and it invades all types of organic substrates whenever conditions are favourable for its growth. Favourable conditions include high moisture content (at least 7\\\%) and high temperature. Aflatoxins B1 (AFB1) are contaminants of improperly stored foods; they are potent genotoxic and carcinogenic compounds, exerting their effects through damage to DNA. They can also induce mutations that increase oxidative damage (PMID: 17214555). Crops which are frequently affected by Aspergillus contamination include cereals (maize, sorghum, pearl millet, rice, wheat), oilseeds (peanut, soybean, sunflower, cotton), spices (chile peppers, black pepper, coriander, turmeric, ginger), and tree nuts (almond, pistachio, walnut, coconut, brazil nut).
Production by Aspergillus flavus and Aspergillus parasiticus. Toxin causing Turkey X disease. One of the most potent carcinogens known in animals. Potential food contaminant especies in grains and nuts
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
D009676 - Noxae > D011042 - Poisons > D000348 - Aflatoxins
Aflatoxin B1 (AFB1) is a Class 1A carcinogen, which is a secondary metabolite of Aspergillus flavus and A. parasiticus. Aflatoxin B1 (AFB1) mainly induces the transversion of G-->T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in mutation[1][2].

同义名列表

16 个代谢物同义名

(3S,7R)-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.0^{2,9}.0^{3,7}.0^{13,17}]nonadeca-1(12),2(9),4,10,13(17)-pentaene-16,18-dione; 2,3,6Aalpha,9aalpha-tetrahydro-4-methoxycyclopenta(c)furo(3,2:4,5)furo(2,3-H)(1)benzopyran-1,11-dione; 4-(Methyloxy)-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3,2:4,5]furo[2,3-h]chromene-1,11-dione; Aflatoxin b1 dihydrochloride, (6ar-cis)-isomer; Aflatoxin b1, (6ar-cis)-isomer, 14C-labeled; Aflatoxin b1, (6ar-cis)-isomer, 2H-labeled; Aflatoxin b1, (6ar-cis)-isomer, 3H-labeled; Aflatoxin b1, cis(+,-)-isomer; (-)-Aflatoxin b1; Aflatoxin B1; Aflatoxin b; HSDB-3453; HSDB 3453; AFBI; AFB1; Aflatoxin B1



数据库引用编号

25 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(6)

BioCyc(1)

PlantCyc(0)

代谢反应

83 个相关的代谢反应过程信息。

Reactome(81)

BioCyc(1)

  • aflatoxins B1 and G1 biosynthesis: 8-O-methylsterigmatocystin + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ CO2 + H2O + MeOH + aflatoxin B1 + an oxidized [NADPH-hemoprotein reductase]

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

34 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Akshay Kumar, Tanya Singh Raghuvanshi, Surya Pratap, Horesh Kumar, Bhanu Prakash. Nanofabrication of citronellal with chitosan biopolymer to boost its efficacy against aflatoxin B1 and Aspergillus flavus mediated biodeterioration of active ingredient of Piper longum. Food chemistry. 2024 Aug; 449(?):139240. doi: 10.1016/j.foodchem.2024.139240. [PMID: 38599109]
  • Ya-Nan Gao, Zi-Wei Wang, Chuan-You Su, Jia-Qi Wang, Nan Zheng. Omics analysis revealed the intestinal toxicity induced by aflatoxin B1 and aflatoxin M1. Ecotoxicology and environmental safety. 2024 Jun; 278(?):116336. doi: 10.1016/j.ecoenv.2024.116336. [PMID: 38691883]
  • Zi-Yong Chu, Xue-Jiao Zi. Network toxicology and molecular docking for the toxicity analysis of food contaminants: A case of Aflatoxin B1. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Jun; 188(?):114687. doi: 10.1016/j.fct.2024.114687. [PMID: 38663764]
  • Anmin Guo, Yi Zhang, Yutong Ji, Xinhua Chen, Wei Zhang, Xuemei Liu, Dongdong Yan, Wensheng Fang, Yuan Li, Aocheng Cao, Qiuxia Wang. The potential for reducing aflatoxin B1 contamination of stored peanuts by soil disinfection. Journal of hazardous materials. 2024 May; 469(?):133916. doi: 10.1016/j.jhazmat.2024.133916. [PMID: 38479137]
  • M J Nava-Ramírez, J A Maguey-González, S Gómez-Rosales, J O Hernández-Ramírez, J D Latorre, Xiangwei Du, C López-Coello, B M Hargis, G Téllez-Isaías, A Vázquez-Durán, A Méndez-Albores. Efficacy of powdered alfalfa leaves to ameliorate the toxic effects of aflatoxin B1 in turkey poults. Mycotoxin research. 2024 May; 40(2):269-277. doi: 10.1007/s12550-024-00527-4. [PMID: 38421516]
  • Lu Zhang, Ying Liu, Qiongyi Zhang, Weiyu Yao, Zenghui Zhao, Xiao Wang, Yongzhan Bao, Wanyu Shi. Salvia miltiorrhiza polysaccharide mitigates AFB1-induced liver injury in rabbits. Ecotoxicology and environmental safety. 2024 May; 276(?):116344. doi: 10.1016/j.ecoenv.2024.116344. [PMID: 38636259]
  • Zahra Mozafari, Masoomeh Shams-Ghahfarokhi, Mahdi Yahyazadeh, Mehdi Razzaghi-Abyaneh. Effects of Tripleurospermum caucasicum, Salvia rosmarinus and Tanacetum fruticulosum essential oils on aflatoxin B1 production and aflR gene expression in Aspergillus flavus. International journal of food microbiology. 2024 Apr; 415(?):110639. doi: 10.1016/j.ijfoodmicro.2024.110639. [PMID: 38417281]
  • Ying Li, Boyu Jia, Pengyue Song, Nan Long, Linchun Shi, Peng Li, Jiabo Wang, Lidong Zhou, Weijun Kong. Precision-SELEX aptamer screening for the colorimetric and fluorescent dual-readout aptasensing of AFB1 in food. Food chemistry. 2024 Mar; 436(?):137661. doi: 10.1016/j.foodchem.2023.137661. [PMID: 37826895]
  • Rhulani Makhuvele, Kenn Foubert, Nina Hermans, Luc Pieters, Luc Verschaeve, Esameldin Elgorashi. Hepatoprotective effects of leaf extract of Annona senegalensis against aflatoxin B1 toxicity in rats. The Onderstepoort journal of veterinary research. 2024 Mar; 91(1):e1-e6. doi: 10.4102/ojvr.v91i1.2133. [PMID: 38572889]
  • Wenjuan Wu, Ying Li, Pengyue Song, Qingbin Xu, Doudou Lei, Jiabo Wang, Bin Fu, Weijun Kong. UiOL@AIEgens-assisted lateral flow immunosensor for the ultrasensitive dual-modal point-of-care detection of aflatoxin B1. Journal of hazardous materials. 2024 Mar; 465(?):133103. doi: 10.1016/j.jhazmat.2023.133103. [PMID: 38043421]
  • Yongli Ye, Tingwei Wang, Jia-Sheng Wang, Jian Ji, Xiao Ning, Xiulan Sun. Antibiotic altered liver damage induced by aflatoxin B1 exposure in mice by modulating the gut microbiota. Environmental pollution (Barking, Essex : 1987). 2024 Feb; 343(?):123291. doi: 10.1016/j.envpol.2024.123291. [PMID: 38176639]
  • Xuanxuan Jiang, Haiyan Liu, Yanli You, Gaolong Zhong, Zhiyan Ruan, Jianzhao Liao, Hui Zhang, Jiaqiang Pan, Zhaoxin Tang, Lianmei Hu. Multi-omics reveals the protective effects of curcumin against AFB1-induced oxidative stress and inflammatory damage in duckling intestines. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2024 Feb; 276(?):109815. doi: 10.1016/j.cbpc.2023.109815. [PMID: 38061615]
  • Prem Pratap Singh, Atul Kumar Jaiswal, Ritu Singh, Akshay Kumar, Vishal Gupta, Tanya Singh Raghuvanshi, Angad Sharma, Bhanu Prakash. Assessment of Trachyspermum ammi essential oil against Aspergillus flavus, aflatoxin B1 contamination, and post-harvest quality of Sorghum bicolor. Food chemistry. 2024 Jan; 443(?):138502. doi: 10.1016/j.foodchem.2024.138502. [PMID: 38306909]
  • Chushu Zhang, Haixiang Zhou, Shining Cao, Jing Chen, Chunjuan Qu, Yueyi Tang, Mian Wang, Lifei Zhu, Xiaoyue Liu, Jiancheng Zhang. A Magnetic Reduced Graphene Oxide Nanocomposite: Synthesis, Characterization, and Application for High-Efficiency Detoxification of Aflatoxin B1. Toxins. 2024 01; 16(1):. doi: 10.3390/toxins16010057. [PMID: 38276533]
  • Yiyang Yuan, Mei Li, Xinghui Qiu. Chicken CYP1A5 is able to hydroxylate aflatoxin B1 in aflatoxin M1. Toxicon : official journal of the International Society on Toxinology. 2024 Jan; 239(?):107625. doi: 10.1016/j.toxicon.2024.107625. [PMID: 38244865]
  • Ahmed E Altyar, Osama A Kensara, Ahmed E Noreldin, Ghadeer M Albadrani, Fatma M El-Demerdash, Amany A Sayed, Marina Piscopo, Zuhair M Mohammedsaleh, Muath Q Al-Ghadi, Nehmat Ghaboura, Mohamed M Abdel-Daim. Spirulina platensis ameliorates hepatic oxidative stress and DNA damage induced by aflatoxin B1 in rats. Toxicon : official journal of the International Society on Toxinology. 2024 Jan; 237(?):107553. doi: 10.1016/j.toxicon.2023.107553. [PMID: 38072319]
  • Chenggang Song, Jian Yang, Yanduo Wang, Gang Ding, Lanping Guo, Jianchun Qin. Mechanisms and transformed products of aflatoxin B1 degradation under multiple treatments: a review. Critical reviews in food science and nutrition. 2024; 64(8):2263-2275. doi: 10.1080/10408398.2022.2121910. [PMID: 36102160]
  • Huimin Ma, Qi Chen, Haiming Yang, Xiaoli Wan. Effects of lycopene on the growth performance, meat quality, and antioxidant capacity of broiler chickens challenged with aflatoxin B1. Journal of food science. 2024 Jan; 89(1):96-103. doi: 10.1111/1750-3841.16848. [PMID: 37983886]
  • Neenu Amminikutty, Veronica Spalenza, Watanya Jarriyawattanachaikul, Paola Badino, Maria Teresa Capucchio, Elena Colombino, Achille Schiavone, Donato Greco, Vito D'Ascanio, Giuseppina Avantaggiato, Sihem Dabbou, Carlo Nebbia, Flavia Girolami. Turmeric Powder Counteracts Oxidative Stress and Reduces AFB1 Content in the Liver of Broilers Exposed to the EU Maximum Levels of the Mycotoxin. Toxins. 2023 Dec; 15(12):. doi: 10.3390/toxins15120687. [PMID: 38133191]
  • Honghui Shi, Jiaxin Li, Yan Zhao, Jiangdi Mao, Haifeng Wang, Junli Zhu. Effect of Aspergillus flavus contamination on the fungal community succession, mycotoxin production and storage quality of maize kernels at various temperatures. Food research international (Ottawa, Ont.). 2023 Dec; 174(Pt 2):113662. doi: 10.1016/j.foodres.2023.113662. [PMID: 37981378]
  • Kai Zhu, Pengyan Wang, Xinming Qu. Study on CdSe/ZnS Quantum Dot Fluorescence Immunoprobe for Detection of Aflatoxin B1 in 5 Traditional Chinese Medicines. Studies in health technology and informatics. 2023 Nov; 308(?):105-110. doi: 10.3233/shti230830. [PMID: 38007731]
  • Zishuang Wang, Xiabing Li, Tiancai Wang, Guangqin Liao, Jingyi Gu, Ruyan Hou, Jing Qiu. Lipidomic profiling study on neurobehavior toxicity in zebrafish treated with aflatoxin B1. The Science of the total environment. 2023 Nov; 898(?):165553. doi: 10.1016/j.scitotenv.2023.165553. [PMID: 37459993]
  • Zhini He, Zihui Chen, Yunying Mo, Xiaodan Lu, Yanheng Luo, Shaoliang Lin, Yanxu Zhong, Junfeng Deng, Shixiong Zheng, Lei Xia, Hang Wu, Michael N Routledge, Ye Hong, Xiaoyu Xian, Xingfen Yang, Yunyun Gong. Assessment of the Adverse Health Effects of Aflatoxin Exposure from Unpackaged Peanut Oil in Guangdong, China. Toxins. 2023 Nov; 15(11):. doi: 10.3390/toxins15110646. [PMID: 37999509]
  • Xuehua An, Shanshan Di, Xinquan Wang, Chong Cao, Dou Wang, Liezhong Chen, Yanhua Wang. Combined toxicity of aflatoxin B1 and tebuconazole to the embryo development of zebrafish (Danio rerio). Chemosphere. 2023 Nov; 346(?):140612. doi: 10.1016/j.chemosphere.2023.140612. [PMID: 37931711]
  • Felipe Penagos-Tabares, Mubarik Mahmood, Muhammad Zafar Ullah Khan, Hafiz Muhammad Amjad Talha, Muhammad Sajid, Kanwal Rafique, Saima Naveed, Johannes Faas, Juan Ignacio Artavia, Michael Sulyok, Anneliese Müller, Rudolf Krska, Qendrim Zebeli. Co-occurrence of mycotoxins and other fungal metabolites in total mixed rations of cows from dairy farms in Punjab, Pakistan. Mycotoxin research. 2023 Nov; 39(4):421-436. doi: 10.1007/s12550-023-00502-5. [PMID: 37665547]
  • Fazul Nabi, Weilai Tao, Zhenzhen Li, Qin Lu, Jialing Xie, Benazir Sahito, Jameel Ahmed Buzdar, Juan Liu. Penthorum chinense Prush extract alleviates aflatoxin B1-induced toxicity, oxidative stress and apoptosis via mediating Nrf2 signaling pathway in the Bursa of Fabricius of broilers. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023 Oct; ?(?):109779. doi: 10.1016/j.cbpc.2023.109779. [PMID: 37871871]
  • Haiyan Liu, Ying He, Xinglin Gao, Tong Li, Baoxin Qiao, Lixuan Tang, Juan Lan, Qian Su, Zhiyan Ruan, Zhaoxin Tang, Lianmei Hu. Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis. Mycotoxin research. 2023 Oct; ?(?):. doi: 10.1007/s12550-023-00504-3. [PMID: 37782431]
  • Lu Zhang, Shaowen Shi, Ying Liu, Yuqing Cui, Yixuan Zhu, Yongzhan Bao, Baojiang Chen, Wanyu Shi. Aflatoxin B1 triggers apoptosis in rabbit hepatocytes via mediating oxidative stress and switching on the mitochondrial apoptosis pathway. Ecotoxicology and environmental safety. 2023 Sep; 264(?):115478. doi: 10.1016/j.ecoenv.2023.115478. [PMID: 37716070]
  • Xuesong Li, Jie Cheng, Kun Zeng, Shulin Wei, Jiaxuan Xiao, Yanyan Lu, Fang Zhu, Zhanhui Wang, Kun Wang, Xiangyang Wu, Zhen Zhang. Accelerated Hybridization Chain Reaction Kinetics Using Poly DNA Tetrahedrons and Its Application in Detection of Aflatoxin B1. ACS applied materials & interfaces. 2023 Sep; 15(35):41237-41246. doi: 10.1021/acsami.3c05506. [PMID: 37625096]
  • Marianna Pauletto, Mery Giantin, Roberta Tolosi, Irene Bassan, Anisa Bardhi, Andrea Barbarossa, Ludovica Montanucci, Anna Zaghini, Mauro Dacasto. Discovering the Protective Effects of Quercetin on Aflatoxin B1-Induced Toxicity in Bovine Foetal Hepatocyte-Derived Cells (BFH12). Toxins. 2023 09; 15(9):. doi: 10.3390/toxins15090555. [PMID: 37755981]
  • Qiuling Du, Wei Zhang, Ning Xu, Xianhong Jiang, Jie Cheng, Ruiguo Wang, Peilong Wang. Efficient and simultaneous removal of aflatoxin B1, B2, G1, G2, and zearalenone from vegetable oil by use of a metal-organic framework absorbent. Food chemistry. 2023 Aug; 418(?):135881. doi: 10.1016/j.foodchem.2023.135881. [PMID: 36966721]
  • Xi Tang, Yi-Fan Cai, Xiao-Mei Yu, Wen-Wen Zhou. Detoxification of aflatoxin B1 by Bacillus aryabhattai through conversion of double bond in terminal furan. Journal of applied microbiology. 2023 Aug; ?(?):. doi: 10.1093/jambio/lxad192. [PMID: 37634085]
  • Chi Feng, Hongxia Bai, Xu Chang, Zhixuan Wu, Wu Dong, Qianqian Ma, Jingfeng Yang. Aflatoxin B1-induced early developmental hepatotoxicity in larvae zebrafish. Chemosphere. 2023 Aug; ?(?):139940. doi: 10.1016/j.chemosphere.2023.139940. [PMID: 37634582]
  • Solomon E Owumi, Angel O Umez, Uche Arunsi, Chioma E Irozuru. Dietary aflatoxin B1 and antimalarial-a lumefantrine/artesunate-therapy perturbs male rat reproductive function via pro-inflammatory and oxidative mechanisms. Scientific reports. 2023 07; 13(1):12172. doi: 10.1038/s41598-023-39455-1. [PMID: 37500724]
  • Yong-Mei Hu, Yi-Rong Wang, Wen-Bin Zhao, Yan Yan Ding, Zheng-Rong Wu, Guang-Han Wang, Peng Deng, Shao-Yong Zhang, Jun-Xia An, Zhi-Jun Zhang, Xiong-Fei Luo, Ying-Qian Liu. Efficacy of pterostilbene suppression on Aspergillus flavus growth, aflatoxin B1 biosynthesis and potential mechanisms. International journal of food microbiology. 2023 Jul; 404(?):110318. doi: 10.1016/j.ijfoodmicro.2023.110318. [PMID: 37454507]
  • Fei Ma, Qi Guo, Zhaowei Zhang, Xiaoxia Ding, Liangxiao Zhang, Peiwu Li, Li Yu. Simultaneous removal of aflatoxin B1 and zearalenone in vegetable oils by hierarchical fungal mycelia@graphene oxide@Fe3O4 adsorbent. Food chemistry. 2023 Jul; 428(?):136779. doi: 10.1016/j.foodchem.2023.136779. [PMID: 37413832]
  • Dapeng Su, Weike Jiang, Qingsong Yuan, Lanping Guo, Qin Liu, Mengmeng Zhang, Chuangzhi Kang, Chenghong Xiao, Changgui Yang, Liangyuan Li, Chunyun Xu, Tao Zhou, Jinqiang Zhang. Chronic exposure to aflatoxin B1 increases hippocampal microglial pyroptosis and vulnerability to stress in mice. Ecotoxicology and environmental safety. 2023 Jun; 258(?):114991. doi: 10.1016/j.ecoenv.2023.114991. [PMID: 37172405]
  • Qian Wang, Chengyi Xiong, Jingwen Li, Qianchun Deng, Xiuhua Zhang, Shengfu Wang, Miao-Miao Chen. High-performance electrochemiluminescence sensors based on ultra-stable perovskite quantum dots@ZIF-8 composites for aflatoxin B1 monitoring in corn samples. Food chemistry. 2023 Jun; 410(?):135325. doi: 10.1016/j.foodchem.2022.135325. [PMID: 36610091]
  • Martina Loi, Silvana De Leonardis, Biancamaria Ciasca, Costantino Paciolla, Giuseppina Mulè, Miriam Haidukowski. Aflatoxin B1 Degradation by Ery4 Laccase: From In Vitro to Contaminated Corn. Toxins. 2023 Apr; 15(5):. doi: 10.3390/toxins15050310. [PMID: 37235345]
  • Shenglan Yuan, Yongjun Wu, Jing Jin, Shuoqiu Tong, Lincheng Zhang, Yafei Cai. Biocontrol Capabilities of Bacillus subtilis E11 against Aspergillus flavus In Vitro and for Dried Red Chili (Capsicum annuum L.). Toxins. 2023 04; 15(5):. doi: 10.3390/toxins15050308. [PMID: 37235343]
  • Tadewos Hadero Medalcho, Kebede Abegaz, Engida Dessalegn, Juan Mate. Aflatoxin B1 Detoxification Potentials of Garlic, Ginger, Cardamom, Black Cumin, and Sautéing in Ground Spice Mix Red Pepper Products. Toxins. 2023 Apr; 15(5):. doi: 10.3390/toxins15050307. [PMID: 37235342]
  • Roua Gabriela Popescu, George Cătălin Marinescu, Andreea Luminița Rădulescu, Daniela Eliza Marin, Ionelia Țăranu, Anca Dinischiotu. Natural Antioxidant By-Product Mixture Counteracts the Effects of Aflatoxin B1 and Ochratoxin A Exposure of Piglets after Weaning: A Proteomic Survey on Liver Microsomal Fraction. Toxins. 2023 04; 15(4):. doi: 10.3390/toxins15040299. [PMID: 37104237]
  • Yuan Zhao, Wenqin Wu, Xiaoqian Tang, Qi Zhang, Jin Mao, Li Yu, Peiwu Li, Zhaowei Zhang. A universal CRISPR/Cas12a-powered intelligent point-of-care testing platform for multiple small molecules in the healthcare, environment, and food. Biosensors & bioelectronics. 2023 Apr; 225(?):115102. doi: 10.1016/j.bios.2023.115102. [PMID: 36724657]
  • Jin-Xian Lin, Chi-Yu Xu, Xin-Mou Wu, Lin Che, Ting-Yu Li, Su-Min Mo, Dong-Bei Guo, Zhong-Ning Lin, Yu-Chun Lin. Rab7a-mTORC1 signaling-mediated cholesterol trafficking from the lysosome to mitochondria ameliorates hepatic lipotoxicity induced by aflatoxin B1 exposure. Chemosphere. 2023 Apr; 320(?):138071. doi: 10.1016/j.chemosphere.2023.138071. [PMID: 36754296]
  • Xue Yang, Xue Li, Yanan Gao, Jiaqi Wang, Nan Zheng. Integrated Metabolomics and Lipidomics Analysis Reveals Lipid Metabolic Disorder in NCM460 Cells Caused by Aflatoxin B1 and Aflatoxin M1 Alone and in Combination. Toxins. 2023 03; 15(4):. doi: 10.3390/toxins15040255. [PMID: 37104193]
  • Lin Che, Jing Huang, Jin-Xian Lin, Chi-Yu Xu, Xin-Mou Wu, Ze-Bang Du, Jia-Shen Wu, Zhong-Ning Lin, Yu-Chun Lin. Aflatoxin B1 exposure triggers hepatic lipotoxicity via p53 and perilipin 2 interaction-mediated mitochondria-lipid droplet contacts: An in vitro and in vivo assessment. Journal of hazardous materials. 2023 03; 445(?):130584. doi: 10.1016/j.jhazmat.2022.130584. [PMID: 37055989]
  • Hong-Xia Zhang, Wei-Ke Jiang, Chang-Gui Yang, Qing-Song Yuan, Lan-Ping Guo, Yuan-Wen Shen, Ni-Ting Wen, Jin-Qiang Zhang, Tao Zhou. [Contamination status and exposure risk of mycotoxins in Coicis Semen]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Mar; 48(6):1491-1497. doi: 10.19540/j.cnki.cjcmm.20221205.101. [PMID: 37005836]
  • Baoxin Qiao, Ying He, Xinglin Gao, Haiyan Liu, Gan Rao, Qian Su, Zhiyan Ruan, Zhaoxin Tang, Lianmei Hu. Curcumin attenuates AFB1-induced duck liver injury by inhibiting oxidative stress and lysosomal damage. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Feb; 172(?):113593. doi: 10.1016/j.fct.2022.113593. [PMID: 36596445]
  • Loise Njoki, Sheila Okoth, Peter Wachira, Abigael Ouko, James Mwololo, Margherita Rizzu, Safa Oufensou, Truphosa Amakhobe. Evaluation of Agronomic Characteristics, Disease Incidence, Yield Performance, and Aflatoxin Accumulation among Six Peanut Varieties (Arachis hypogea L.) Grown in Kenya. Toxins. 2023 01; 15(2):. doi: 10.3390/toxins15020111. [PMID: 36828425]
  • Isaac A Adedara, Solomon E Owumi. Neurobehavioral and biochemical responses to artemisinin-based drug and aflatoxin B1 co-exposure in rats. Mycotoxin research. 2023 Jan; ?(?):. doi: 10.1007/s12550-023-00474-6. [PMID: 36701108]
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