Linoleic acid (BioDeep_00000002188)

 

Secondary id: BioDeep_00000028189, BioDeep_00000175488, BioDeep_00000229626, BioDeep_00000405330, BioDeep_00000859403, BioDeep_00000859921

natural product human metabolite PANOMIX_OTCML-2023 Endogenous Exogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


C18:2 9C, 12C Omega6 todos cis-9,12-octadienoico

化学式: C18H32O2 (280.2402)
中文名称: 亚油酸, 十八二烯酸, 亚油酸，罂酸, 亚油酸60-74\%
谱图信息: 最多检出来源 Homo sapiens(blood) 18.32%

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Linoleic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/linoleic_acid (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000002188). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(=C\C/C=C/CCCCCCCC(=O)O)\CCCCC
InChI: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9+

描述信息

Linoleic acid is a doubly unsaturated fatty acid, also known as an omega-6 fatty acid, occurring widely in plant glycosides. In this particular polyunsaturated fatty acid (PUFA), the first double bond is located between the sixth and seventh carbon atom from the methyl end of the fatty acid (n-6). Linoleic acid is an essential fatty acid in human nutrition because it cannot be synthesized by humans. It is used in the biosynthesis of prostaglandins (via arachidonic acid) and cell membranes (From Stedman, 26th ed). Linoleic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.

Linoleic acid (LA) is an organic compound with the formula HOOC(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups (−CH=CH−) are cis. It is a fatty acid sometimes denoted 18:2 (n-6) or 18:2 cis-9,12. A linoleate is a salt or ester of this acid.[5]

Linoleic acid is a polyunsaturated, omega-6 fatty acid. It is a colorless liquid that is virtually insoluble in water but soluble in many organic solvents.[2] It typically occurs in nature as a triglyceride (ester of glycerin) rather than as a free fatty acid.[6] It is one of two essential fatty acids for humans, who must obtain it through their diet,[7] and the most essential, because the body uses it as a base to make the others.

The word "linoleic" derives from Latin linum 'flax', and oleum 'oil', reflecting the fact that it was first isolated from linseed oil.

同义名列表

75 个代谢物同义名

C18:2 9C, 12C Omega6 todos cis-9,12-octadienoico; Linoleic acid, potassium salt, (Z,Z)-isomer; Linoleic acid, ammonium salt, (Z,Z)-isomer; Linoleic acid, calcium salt, (Z,Z)-isomer; Linoleic acid, sodium salt, (e,e)-isomer; Linoleic acid, (Z,Z)-isomer, 14C-labeled; Linoleic acid, sodium salt, (Z,Z)-isomer; trans,trans-9,12-Octadecadienoic acid; 9-trans,12-trans-Octadecadienoic acid; 9 trans,12 trans Octadecadienoic acid; cis-Delta(9,12)-Octadecadienoic acid; (9Z,12Z)-octadeca-9,12-dienoic acid; cis-9, cis-12-octadecadienoic acid; (9Z,12Z)-9,12-Octadecadienoic acid; all-cis-9,12-Octadecadienoic acid; 9-cis,12-cis-Octadecadienoic acid; cis,cis-9,12-octadecadienoic acid; cis-9,cis-12-Octadecadienoic acid; cis-delta(9,12)-Octadecadienoate; cis-Δ(9,12)-octadecadienoic acid; (Z,Z)-9,12-Octadecadienoic acid; (9Z,12Z)-9,12-Octadecadienoate; Linoelaidic acid, (e,Z)-isomer; cis-D9,12-Octadecadienoic acid; (9Z,12Z)-Octadecadienoic acid; all-cis-9,12-Octadecadienoate; cis,cis-9,12-Octadecadienoate; 9-cis,12-cis-Octadecadienoate; cis-9,cis-12-Octadecadienoate; cis-Δ(9,12)-octadecadienoate; (Z,Z)-9,12-Octadecadienoate; Linoleic acid, (e,e)-isomer; Linoleic acid, (Z,Z)-isomer; Linoleic acid, (Z,e)-isomer; 9Z,12Z-octadecadienoic acid; (9Z, 12Z)-Octadecadienoate; Acid, 9,12-octadecadienoic; cis-D9,12-Octadecadienoate; 9-cis,12-cis-Linoleic acid; (9Z,12Z)-Octadecadienoate; 9,12 Octadecadienoic acid; 9,12-Octadecadienoic acid; 9Z,12Z-Octadecadienoate; 9-cis,12-cis-Linoleate; cis,cis-Linoleic acid; 9Z,12Z-Linoleic acid; C18:2, N-6,9 all-cis; Acide cis-linoleique; Linolelaidic acid; cis,cis-Linoleate; Extra linoleic 90; FA(18:2(9Z,12Z)); Linoelaidic acid; Acide linoleique; 9Z,12Z-Linoleate; Acido linoleico; Grape Seed Oil; Telfairic acid; Linoleic acid; Leinolic acid; Linoleic acid; Linolic acid; Emersol 315; Unifac 6550; Polylin 515; Cognac oil; C18:2n-6,9; Linoleate; linoleic; Linolate; FA 18:2; LA; Linoleic acid; Linoleate; Linoleic acid



数据库引用编号

55 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(5)

BioCyc(0)

PlantCyc(0)

代谢反应

786 个相关的代谢反应过程信息。

Reactome(70)

BioCyc(0)

WikiPathways(8)

Plant Reactome(305)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(403)

PharmGKB(0)

539 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AKT1, ALB, APOB, APOE, CASP3, G6PD, PTGS1, SREBF1, XDH
Peripheral membrane protein 3 ALOX15, G6PD, PTGS1
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 4 APOB, HSP90B1, PTGS1, SREBF1
Nucleus 7 AKT1, ALB, APOE, CASP3, HSP90B1, PLCZ1, SREBF1
cytosol 14 AKT1, ALB, ALOX15, APOB, CASP3, EPHX2, G6PD, HSP90B1, LIPE, MB, PLCZ1, PRKCQ, SREBF1, XDH
dendrite 1 APOE
centrosome 1 ALB
nucleoplasm 5 AKT1, ATP2B1, CASP3, PLCZ1, SREBF1
Cell membrane 5 AKT1, ALOX15, ATP2B1, FFAR1, LIPE
lamellipodium 1 AKT1
Multi-pass membrane protein 3 ATP2B1, FFAR1, SREBF1
Golgi apparatus membrane 1 SREBF1
Synapse 1 ATP2B1
cell cortex 1 AKT1
glutamatergic synapse 4 AKT1, APOE, ATP2B1, CASP3
Golgi apparatus 3 ALB, APOE, PTGS1
Golgi membrane 1 SREBF1
lysosomal membrane 1 EGF
neuronal cell body 3 APOB, APOE, CASP3
postsynapse 1 AKT1
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 2 APOB, HSP90B1
Cytoplasm, cytosol 3 ALOX15, G6PD, LIPE
plasma membrane 9 AKT1, ALOX15, APOB, APOE, ATP2B1, EGF, FFAR1, GCG, PRKCQ
synaptic vesicle membrane 1 ATP2B1
Membrane 8 AKT1, ALOX15, APOE, ATP2B1, EGF, G6PD, HSP90B1, LIPE
basolateral plasma membrane 1 ATP2B1
caveola 1 LIPE
extracellular exosome 10 ALB, APOB, APOE, ATP2B1, EGF, EPHX2, G6PD, HSP90B1, MB, PTGS1
endoplasmic reticulum 4 ALB, APOE, HSP90B1, SREBF1
extracellular space 6 ALB, APOB, APOE, EGF, GCG, XDH
lysosomal lumen 1 APOB
perinuclear region of cytoplasm 2 HSP90B1, PLCZ1
protein-containing complex 4 AKT1, ALB, HSP90B1, SREBF1
intracellular membrane-bounded organelle 4 APOB, ATP2B1, G6PD, PTGS1
Microsome membrane 1 PTGS1
postsynaptic density 1 CASP3
pronucleus 1 PLCZ1
Secreted 4 ALB, APOB, APOE, GCG
extracellular region 6 ALB, APOB, APOE, EGF, GCG, HSP90B1
cytoplasmic side of plasma membrane 2 ALOX15, G6PD
anchoring junction 1 ALB
centriolar satellite 2 G6PD, PRKCQ
photoreceptor outer segment 1 PTGS1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 2 APOB, APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 2 APOB, APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 2 APOB, APOE
microtubule cytoskeleton 1 AKT1
nucleolus 1 PLCZ1
midbody 1 HSP90B1
sarcoplasm 1 MB
Early endosome 2 APOB, APOE
cell-cell junction 1 AKT1
vesicle 1 AKT1
Cytoplasm, perinuclear region 1 PLCZ1
focal adhesion 1 HSP90B1
spindle 1 AKT1
extracellular matrix 1 APOE
Peroxisome 2 EPHX2, XDH
sarcoplasmic reticulum 1 XDH
peroxisomal matrix 1 EPHX2
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 2 APOE, HSP90B1
lateral plasma membrane 1 ATP2B1
neuron projection 1 PTGS1
ciliary basal body 2 AKT1, ALB
chromatin 1 SREBF1
cell projection 1 ATP2B1
centriole 1 ALB
Secreted, extracellular space 1 APOE
spindle pole 1 ALB
blood microparticle 2 ALB, APOE
Basolateral cell membrane 1 ATP2B1
nuclear envelope 1 SREBF1
Endomembrane system 1 PTGS1
endosome lumen 1 APOB
Lipid droplet 3 ALOX15, APOB, LIPE
Membrane, caveola 1 LIPE
Cytoplasmic vesicle membrane 1 SREBF1
Melanosome 2 APOE, HSP90B1
Presynaptic cell membrane 1 ATP2B1
sperm plasma membrane 1 HSP90B1
secretory granule lumen 1 GCG
endoplasmic reticulum lumen 5 ALB, APOB, APOE, GCG, HSP90B1
platelet alpha granule lumen 2 ALB, EGF
endoplasmic reticulum exit site 1 APOB
immunological synapse 2 ATP2B1, PRKCQ
aggresome 1 PRKCQ
ER to Golgi transport vesicle membrane 1 SREBF1
clathrin-coated endocytic vesicle membrane 3 APOB, APOE, EGF
Sarcoplasmic reticulum lumen 1 HSP90B1
synaptic cleft 1 APOE
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, COPII-coated vesicle membrane 1 SREBF1
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 3 APOB, APOE, HSP90B1
[Glucagon-like peptide 1]: Secreted 1 GCG
Cytoplasm, sarcoplasm 1 MB
chylomicron remnant 2 APOB, APOE
intermediate-density lipoprotein particle 2 APOB, APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
sperm head 1 PLCZ1
mature chylomicron 1 APOB
endoplasmic reticulum chaperone complex 1 HSP90B1
photoreceptor ribbon synapse 1 ATP2B1
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane 1 SREBF1
[Processed sterol regulatory element-binding protein 1]: Nucleus 1 SREBF1
[Isoform SREBP-1aDelta]: Nucleus 1 SREBF1
[Isoform SREBP-1cDelta]: Nucleus 1 SREBF1
ciliary transition fiber 1 ALB


文献列表

  • Shuo Wang, Wenbin Zhou, Zhongyu Wei, Hang Li, Yuxiu Xiao. Solvent-tuned perovskite heterostructures enable visual linoleic acid assay and edible oil species discrimination via wavelength shift. Food chemistry. 2024 Aug; 449(?):139190. doi: 10.1016/j.foodchem.2024.139190. [PMID: 38579653]
  • Karolina Beton-Mysur, Jakub Surmacki, Beata Brożek-Płuska. Raman-AFM-fluorescence-guided impact of linoleic and eicosapentaenoic acids on subcellular structure and chemical composition of normal and cancer human colon cells. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2024 Jul; 315(?):124242. doi: 10.1016/j.saa.2024.124242. [PMID: 38581725]
  • Ruifang Feng, Qinye Yu, Yulong Bao, Liang Chen, Yongkang Luo, Yuqing Tan, Hui Hong. Myofibrillar protein lipoxidation in fish induced by linoleic acid and 4-hydroxy-2-nonenal: Insights from LC-MS/MS analysis. Food research international (Ottawa, Ont.). 2024 Jul; 187(?):114357. doi: 10.1016/j.foodres.2024.114357. [PMID: 38763641]
  • Haifaa Laroui, Thoraya Guemmaz, Fatima Zerargui, Karima Saffidine, Sara Guenifi, Lekhmici Arrar, Seddik Khennouf, Gokhan Zengin, Abderrahmane Baghiani. Antioxidant and anti-inflammatory potentials of Ammodaucus leucotrichus Coss. & Durieu seeds' extracts: In vitro and in vivo studies. Journal of ethnopharmacology. 2024 May; 326(?):117964. doi: 10.1016/j.jep.2024.117964. [PMID: 38401663]
  • Swaraj Kumar Babu, Dibya Ranjan Sahoo, Prajna Parimita Mohanta, Pradeep Kumar Naik. Exploring the antifilarial potential of an important medicinal plant Typhonium trilobatum (L. Schoot): Isolation, characterization, and structural elucidation of bioactive compounds against Brugia malayi. Journal of ethnopharmacology. 2024 May; 326(?):117858. doi: 10.1016/j.jep.2024.117858. [PMID: 38346526]
  • Jingzhi Nie, Wenyue Ma, Xueyuan Ma, De Zhu, Xin Li, Caijin Wang, Guofeng Xu, Canni Chen, Dengjie Luo, Sichen Xie, Guanjing Hu, Peng Chen. Integrated Transcriptomic and Metabolomic Analysis Reveal the Dynamic Process of Bama Hemp Seed Development and the Accumulation Mechanism of α-Linolenic Acid and Linoleic Acid. Journal of agricultural and food chemistry. 2024 May; 72(19):10862-10878. doi: 10.1021/acs.jafc.3c09309. [PMID: 38712687]
  • Tianmu He, Lijuan Xiong, Kexin Lin, Jing Yi, Cancan Duan, Jianyong Zhang. Functional metabolomics reveals arsenic-induced inhibition of linoleic acid metabolism in mice kidney in drinking water. Environmental pollution (Barking, Essex : 1987). 2024 May; 349(?):123949. doi: 10.1016/j.envpol.2024.123949. [PMID: 38636836]
  • Xiao-Yu Zhang, Kai-Rou Xia, Ya-Ni Wang, Pei Liu, Er-Xin Shang, Cong-Yan Liu, Yu-Ping Liu, Ding Qu, Wei-Wen Li, Jin-Ao Duan, Yan Chen, Huang-Qin Zhang. Unraveling the pharmacodynamic substances and possible mechanism of Trichosanthis Pericarpium in the treatment of coronary heart disease based on plasma pharmacochemistry, network pharmacology and experimental validation. Journal of ethnopharmacology. 2024 May; 325(?):117869. doi: 10.1016/j.jep.2024.117869. [PMID: 38342153]
  • Natalia Łozińska, Julia Maldonado-Valderrama, Teresa Del Castillo-Santaella, Yanija Zhou, Dorota Martysiak-Żurowska, Yuanqi Lu, Christian Jungnickel. Bile conjugation and its effect on in vitro lipolysis of emulsions. Food research international (Ottawa, Ont.). 2024 May; 184(?):114255. doi: 10.1016/j.foodres.2024.114255. [PMID: 38609233]
  • Nobuyuki Fukuoka, Ryusei Watanabe, Tatsuro Hamada. Impact of changes in root biomass on the occurrence of internal browning in radish root. Plant physiology and biochemistry : PPB. 2024 May; 210(?):108563. doi: 10.1016/j.plaphy.2024.108563. [PMID: 38554535]
  • Guiping Gong, Linpei Liu, Bo Wu, Jianting Li, Mingxiong He, Guoquan Hu. Simultaneous production of algal biomass and lipid by heterotrophic cultivation of linoleic acid-rich oleaginous microalga Chlorella sorokiniana using high acetate dosage. Bioresource technology. 2024 May; 399(?):130566. doi: 10.1016/j.biortech.2024.130566. [PMID: 38467262]
  • Xuan Liu, Weifei Wang, Zhong Li, Long Xu, Dongming Lan, Yonghua Wang. Lipidomics analysis unveils the dynamic alterations of lipid degradation in rice bran during storage. Food research international (Ottawa, Ont.). 2024 May; 184(?):114243. doi: 10.1016/j.foodres.2024.114243. [PMID: 38609222]
  • Zongyao Huyan, Nicoletta Pellegrini, Josep Rubert, Wilma T Steegenga, Edoardo Capuano. Levels of lipid-derived gut microbial metabolites differ among plant matrices in an in vitro model of colon fermentation. Food research international (Ottawa, Ont.). 2024 May; 184(?):114230. doi: 10.1016/j.foodres.2024.114230. [PMID: 38609219]
  • Zhixiong Chen, Ni Hong, Cui Yan, Zhongbo Zheng, Jie Xi, Ping Cao. The potential of Paeonia lactiflora pall seeds oil as a pure natural cosmetics raw material: In Vitro findings. Journal of cosmetic dermatology. 2024 May; 23(5):1875-1883. doi: 10.1111/jocd.16204. [PMID: 38450923]
  • Xueyan Gu, Heng Wang, Lei Wang, Kang Zhang, Yuhu Tian, Xiaoya Wang, Guowei Xu, Zhiting Guo, Saad Ahmad, Hanyurwumutima Egide, Jiahui Liu, Jianxi Li, Huub F J Savelkoul, Jingyan Zhang, Xuezhi Wang. The antioxidant activity and metabolomic analysis of the supernatant of Streptococcus alactolyticus strain FGM. Scientific reports. 2024 04; 14(1):8413. doi: 10.1038/s41598-024-58933-8. [PMID: 38600137]
  • Barbara Soldo, Maja Jukić Špika, Igor Pasković, Elma Vuko, Marija Polić Pasković, Ivica Ljubenkov. The Composition of Volatiles and the Role of Non-Traditional LOX on Target Metabolites in Virgin Olive Oil from Autochthonous Dalmatian Cultivars. Molecules (Basel, Switzerland). 2024 Apr; 29(8):. doi: 10.3390/molecules29081696. [PMID: 38675515]
  • Kun-Pyo Kim, Kyung-Oh Shin, Sangmin Lee, Jihyeon Yun, Taehoon Lee, Yunhi Cho. PNPLA1 knockdown inhibits esterification of γ-linolenic acid to ceramide 1 in differentiated keratinocytes. Biochemical and biophysical research communications. 2024 Apr; 702(?):149618. doi: 10.1016/j.bbrc.2024.149618. [PMID: 38340658]
  • Guanglei Ma, Bijie Hu, Siyin Yang, Zixuan Cen, Yiran Zheng, Yan Dong. Benzoxazinoids secreted by wheat root weaken the pathogenicity of Fusarium oxysporum f. sp. fabae by inhibiting linoleic acid and nucleotide metabolisms. Plant cell reports. 2024 Apr; 43(4):109. doi: 10.1007/s00299-024-03188-w. [PMID: 38564014]
  • Keita Nakatsutsumi, Koji Morishita, Todd W Costantini, Tomohiro Adachi, Akira Suekane, Keisuke Suzuki, Mitsuaki Kojima, Makoto Arita, Yasuhiro Otomo. Analysis of lipid metabolites derived from gut microbiota in ischemia-reperfusion model. The journal of trauma and acute care surgery. 2024 Apr; 96(4):542-547. doi: 10.1097/ta.0000000000004230. [PMID: 38079251]
  • Farah M Joujou, Nada El Darra, Hiba N Rajha, Elie Salem Sokhn, Nisreen Alwan. Evaluation of synergistic/antagonistic antibacterial activities of fatty oils from apricot, date, grape, and black seeds. Scientific reports. 2024 03; 14(1):6532. doi: 10.1038/s41598-024-54850-y. [PMID: 38503788]
  • Qing Zhang, Jiaping Ke, Piaopiao Long, Mingchun Wen, Zisheng Han, Liang Zhang, Mengting Zhu. Formation of Furan from Linoleic Acid Thermal Oxidation: (E,E)-2,4-Decadienal as a Critical Intermediate Product. Journal of agricultural and food chemistry. 2024 Feb; 72(8):4384-4392. doi: 10.1021/acs.jafc.3c08604. [PMID: 38354408]
  • Akane Suda, Banlanjo Abdulaziz Umaru, Yui Yamamoto, Hiroki Shima, Yuriko Saiki, Yijun Pan, Liang Jin, Jiaqi Sun, Yi Ling Clare Low, Chitose Suzuki, Takaaki Abe, Kazuhiko Igarashi, Toru Furukawa, Yuji Owada, Yoshiteru Kagawa. Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth. Scientific reports. 2024 02; 14(1):4409. doi: 10.1038/s41598-024-55050-4. [PMID: 38388563]
  • Yoshiro Saito, Noriko Noguchi, Etsuo Niki. Cholesterol is more readily oxidized than phospholipid linoleates in cell membranes to produce cholesterol hydroperoxides. Free radical biology & medicine. 2024 Feb; 211(?):89-95. doi: 10.1016/j.freeradbiomed.2023.12.011. [PMID: 38101585]
  • Dandan Yue, Xuyang Hao, Bei Han, Jiao Xu, Weinan Sun, Xiaoping Guo, Xianlong Zhang, Xiyan Yang. GhL1L1 regulates the contents of unsaturated fatty acids by activating the expression of GhFAD2 genes in cotton. Gene. 2024 Jan; 893(?):147899. doi: 10.1016/j.gene.2023.147899. [PMID: 37839764]
  • Ichiro Koshiishi. [What is the Initiating Reaction for the Lipid Radical Chain Reaction System That can Induce Ferroptotic Cell Death at the Lower Oxygen Content?]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2024 Jan; ?(?):. doi: 10.1248/yakushi.23-00207. [PMID: 38246655]
  • Nirajan Shrestha, Simone L Sleep, Olivia J Holland, Josif Vidimce, Andrew C Bulmer, James S M Cuffe, Anthony V Perkins, Andrew J McAinch, Deanne H Hryciw. Maternal Diet High in Linoleic Acid Alters Offspring Lipids and Hepatic Regulators of Lipid Metabolism in an Adolescent Rat Model. International journal of molecular sciences. 2024 Jan; 25(2):. doi: 10.3390/ijms25021129. [PMID: 38256199]
  • Yunping Yao, Tianliang Wang, Zhiyuan Qiang, Wenqi Du, Changmo Li. Mechanisms of the Formation of Nonvolatile and Volatile Oxidation Products from Methyl Linoleic Acid at High Temperatures. Journal of agricultural and food chemistry. 2024 Jan; 72(1):704-714. doi: 10.1021/acs.jafc.3c04405. [PMID: 38131267]
  • Xiaoli Yang, Chenglin Chi, Wenjing Li, Yanyan Zhang, Shufang Yang, Ruoxuan Xu, Rongxia Liu. Metabolomics and lipidomics combined with serum pharmacochemistry uncover the potential mechanism of Huang-Lian-Jie-Du decoction alleviates atherosclerosis in ApoE-/- mice. Journal of ethnopharmacology. 2024 Jan; 324(?):117748. doi: 10.1016/j.jep.2024.117748. [PMID: 38216103]
  • Ufaq Fayaz, Syed Zameer Hussain, Bazila Naseer, Syed Sheraz Mahdi, Javid Iqbal Mir, Alokesh Ghosh, Arun Jana, Nazrana Rafique Wani, Abida Jabeen, Fehim J Wani, Sobiya Manzoor. Flavor profiling and gene expression studies of indigenous aromatic rice variety (Mushk Budiji) grown at different altitudes of Highland Himalayan regions. Scientific reports. 2024 01; 14(1):1010. doi: 10.1038/s41598-024-51467-z. [PMID: 38200065]
  • Zumer Naeem, Sven Zukunft, Arnaud Huard, Jiong Hu, Bruce D Hammock, Andreas Weigert, Timo Frömel, Ingrid Fleming. Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Jan; 171(?):116127. doi: 10.1016/j.biopha.2024.116127. [PMID: 38198951]
  • Radosław Kowalski, Grażyna Kowalska, Przemysław Mitura, Rafał Rowiński, Urszula Pankiewicz, Joanna Hawlena. The Effect of Peppermint and Thyme Oils on Stabilizing the Fatty Acid Profile of Sunflower Oil. Molecules (Basel, Switzerland). 2024 Jan; 29(2):. doi: 10.3390/molecules29020292. [PMID: 38257205]
  • Xuemei Bao, Danmin Ke, Wei Wang, Fahui Ye, Jiangyi Zeng, Yuan Zong. High fatty acid accumulation and coloration molecular mechanism of the elm mushroom (Pleurotus citrinopileatus). Bioscience, biotechnology, and biochemistry. 2024 Jan; ?(?):. doi: 10.1093/bbb/zbad183. [PMID: 38171531]
  • Prapaporn Chaniad, Arisara Phuwajaroanpong, Walaiporn Plirat, Atthaphon Konyanee, Abdi Wira Septama, Chuchard Punsawad. Assessment of antimalarial activity of crude extract of Chan-Ta-Lee-La and Pra-Sa-Chan-Dang formulations and their plant ingredients for new drug candidates of malaria treatment: In vitro and in vivo experiments. PloS one. 2024; 19(1):e0296756. doi: 10.1371/journal.pone.0296756. [PMID: 38206944]
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