alpha-Tocopherol (BioDeep_00000000778)

 

Secondary id: BioDeep_00000397418, BioDeep_00000405478, BioDeep_00000861719, BioDeep_00001898014

natural product human metabolite PANOMIX_OTCML-2023 blood metabolite Antitumor activity BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R*(4R*,8R*))-(+-)-

化学式: C29H50O2 (430.38106)
中文名称: (+)-α-生育酚, D-α-生育酚, α-维生素 E, 维生素e, DL-α-生育酚, 天然维生素 E, 维生素 E
谱图信息: 最多检出来源 Homo sapiens(feces) 0.18%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

alpha-Tocopherol. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/alpha-tocopherol (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000000778). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1(c2c(c(c(c1O)C)C)O[C@@](CC2)(CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)C)C
InChI: InChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

描述信息

Alpha-tocopherol is a pale yellow, viscous liquid. (NTP, 1992)
(R,R,R)-alpha-tocopherol is an alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. It has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite. It is an enantiomer of a (S,S,S)-alpha-tocopherol.
In 1922, vitamin E was demonstrated to be an essential nutrient. Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active. Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage. The antioxidant effects are currently being researched for use in the treatment of diseases causing bone loss, cardiovascular diseases, diabetes mellitus and associated comorbidities, eye diseases, inflammatory diseases (including skin conditions), lipid disorders, neurological diseases, and radiation damage. Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA.
Vitamin E is a natural product found in Monteverdia ilicifolia, Calea jamaicensis, and other organisms with data available.
Alpha-Tocopherol is the orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.
A generic descriptor for all tocopherols and tocotrienols that exhibit alpha-tocopherol activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of isoprenoids.
See also: Alpha-Tocopherol Acetate (is active moiety of); Tocopherol (related); Vitamin E (related) ... View More ...
alpha-Tocopherol is traditionally recognized as the most active form of vitamin E in humans and is a powerful biological antioxidant. The measurement of "vitamin E" activity in international units (IU) was based on fertility enhancement by the prevention of spontaneous abortions in pregnant rats relative to alpha-Tocopherol. Natural vitamin E exists in eight different forms or isomers: four tocopherols and four tocotrienols. In foods, the most abundant sources of vitamin E are vegetable oils such as palm oil, sunflower, corn, soybean, and olive oil. Nuts, sunflower seeds, and wheat germ are also good sources.
Constituent of many vegetable oils such as soya and sunflower oils. Dietary supplement and nutrient. Nutriceutical with anticancer and antioxidant props. Added to fats and oils to prevent rancidity. The naturally-occurring tocopherol is a single stereoisomer; synthetic forms are a mixture of all eight possible isomers
An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.

α-Tocopherol (alpha-tocopherol) is a type of vitamin E. Its E number is "E307". Vitamin E exists in eight different forms, four tocopherols and four tocotrienols. All feature a chromane ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals and a hydrophobic side chain which allows for penetration into biological membranes. Compared to the others, α-tocopherol is preferentially absorbed and accumulated in humans.

Vitamin E is found in a variety of tissues, being lipid-soluble, and taken up by the body in a wide variety of ways. The most prevalent form, α-tocopherol, is involved in molecular, cellular, biochemical processes closely related to overall lipoprotein and lipid homeostasis. Ongoing research is believed to be "critical for manipulation of vitamin E homeostasis in a variety of oxidative stress-related disease conditions in humans."[2] One of these disease conditions is the α-tocopherol role in the use by malaria parasites to protect themselves from the highly oxidative environment in erythrocytes.[3]

DL-α-Tocopherol. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=16826-11-2 (retrieved 2024-06-29) (CAS RN: 10191-41-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
rel-α-Vitamin E (rel-D-α-Tocopherol) is a vitamin with antioxidant properties and also a mixture[1].
α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].
α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].

同义名列表

178 个代谢物同义名

2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R*(4R*,8R*))-(+-)-; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, [2R-[2R*(4R*,8R*)]]-; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R-(2R*(4R*,8R*)))-; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 2R- 2R*(4R*,8R*) -; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel-; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, (2R)-; (2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-; (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol; (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol; 3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-(2R)-2H-1-benzopyran-6-ol; rel-(2R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-ol; (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol; (R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-ol; (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol; 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- -benzopyran-6-ol; 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1--benzopyran-6-ol; 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol; (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL; (2R)-2-((4R,8R)-4,8,12-trimethyltridecyl)-2,5,7,8-tetramethylchroman-6-ol; (R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ol; (2R,4R,8R)-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol; 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol; rel-(+)--Tocopherol; rel-D--Tocopherol; 07AA93F0-3339-4EEC-B50B-ADB70F657087; ALPHA-TOCOPHEROL, UNSPECIFIED FORM; (+)--Tocopherol; D--Tocopherol; (+)-2R,4R,8R-alpha-Tocopherol; C29H50O2 (D-alpha-tocopherol); (+)-2R,4’R,8’R-α-Tocopherol; (2R,4R,8R)-alpha-Tocopherol; D-ALPHA TOCOPHEROL [MART.]; ALPHA TOCOPHEROL (USP-RS); (2R,4’R,8’R)-α-Tocopherol; (+)-2R,4R,8R-α-Tocopherol; (all-R)-alpha-Tocopherol; R,r,r-.alpha.-tocopherol; (R,R,R)-alpha-Tocopherol; (2R,4R,8R)-a-Tocopherol; (2R,4R,8R)-α-Tocopherol; ALPHA-TOCOPHEROL [HSDB]; .ALPHA.-TOCOPHEROL [MI]; .ALPHA.-TOCOPHEROL, D-; (+)-.alpha.-Tocopherol; (+)- alpha -Tocopherol; alpha-delta-Tocopherol; (+/-)-alpha-Tocopherol; delta-alpha-tocopherol; alpha-TOCOPHEROL (II); alpha-Tocopherol acid; Antisterility vitamin; (+)-ALPHA-TOCOPHEROL-; Tocopherol, d-alpha-; alpha-Tocopherol, D-; RRR-alpha-tocopherol; Rhenogran Ronotec 50; 5,7,8-Trimethyltocol; (all-R)-α-Tocopherol; (R,R,R)-a-Tocopherol; RRR-alpha-tocopheryl; (R,R,R)-α-Tocopherol; (+)-alpha-Tocopherol; ()-alpha-Tocopherol; rel-alpha-Vitamin E; D-alpha tocopherol; D-alpha-Tocopherol; Vitamin E (D-form); alpha-D-Tocopherol; Prestwick3_000404; Alpha-tocopherols; Vitamin e d-alpha; .alpha.-Vitamin E; Alpha-Tocopherol; (+)-α-Tocopherol; alpha Tocopherol; Tocopherol (R,S); Tocopherol alpha; (+)-a-Tocopherol; DL-α-Tocopherol; Vitamin E alpha; alpha-Tokoferol; UNII-H4N855PNZ1; alpha-Vitamin E; alpha-Tocoferol; Vitamin E [USP]; UNII-N9PR3490H9; dl-a-Tocopherol; α-D-Tocopherol; a-D-Tocopherol; rel--Vitamin E; Vitamin Ealpha; DL--Tocopherol; d-a-tocopherol; d-α-Tocopherol; COVI-OX T 30P; BPBio1_000362; α-Tocopherol; a-Tocopherol; Phytogermine; Waynecomycin; Tox21_113208; Tox21_110563; Acne C-Patch; COVI-OX T 50; Tox21_202081; a-Vitamin E; CAS-59-02-9; Syntopherol; Vita plus E; Profecundin; α-Vitamin E; Phytogermin; Vitaplex E; Evitaminum; CONTROX VP; H4N855PNZ1; (+-)-Med-E; -Vitamin E; Vitamin Eα; Vitamin Ea; RIKKI N 70; Tenox GT 1; TOCOPHEROL; N9PR3490H9; E-MIX 40A; Vitamin-E; EPROLIN-S; Viterra E; Tokopharm; Aquasol E; Eprolin S; Emipherol; Vitayonon; VITAMIN E; Vascuals; Spavit E; TENOX GT; Denamone; Etamican; Palmvtee; Pheryl-E; Viprimol; Almefrol; E Prolin; CHEMBL47; J24.260H; Viteolin; Covi-ox; COVIREL; E-Vimin; Eprolin; Epsilan; Endo E; Vita E; Ilitia; Etavit; Evion; ido-E; Esorb; Lan-E; VitaE; Med-E; Vi-E; VIV; (2R,4R,8R)-α-Tocopherol; α-δ-Tocopherol; δ-α-tocopherol; (R,R,R)-α-Tocopherol; (+)-α-Tocopherol; RRR-α-tocopherol; RRR-α-tocopheryl; (+-)-alpha-Tocopherol; d-α-tocopherol; DL-alpha-Tocopherol; α-Tocopherol; rel-D-α-Tocopherol; rel-α-Vitamin E; alpha-Tocopherol



数据库引用编号

43 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(3)

BioCyc(0)

PlantCyc(0)

代谢反应

177 个相关的代谢反应过程信息。

Reactome(42)

BioCyc(5)

WikiPathways(0)

Plant Reactome(3)

INOH(0)

PlantCyc(127)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

121 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tingting Fu, Valentina Calabrese, Sarah Bancel, Hervé Quéau, Laura Garnero, Nicolas Delorme, Khedidja Abbaci, Arnaud Salvador, Arnaud Chaumot, Olivier Geffard, Davide Degli-Esposti, Sophie Ayciriex. ToF-SIMS imaging shows specific lipophilic vitamin alterations in chronic reprotoxicity caused by the emerging contaminant Pravastatin in Gammarus fossarum. Aquatic toxicology (Amsterdam, Netherlands). 2024 Jun; 271(?):106935. doi: 10.1016/j.aquatox.2024.106935. [PMID: 38723468]
  • Ningjian Liang, Hussein Mohamed, Rachel F Pung, Joy Waite-Cusic, David C Dallas. Optimized Ultraviolet-C Processing Inactivates Pathogenic and Spoilage-Associated Bacteria while Preserving Bioactive Proteins, Vitamins, and Lipids in Human Milk. Journal of agricultural and food chemistry. 2024 May; 72(21):12198-12208. doi: 10.1021/acs.jafc.4c02120. [PMID: 38752986]
  • Pernille A Madsen, Søren K Jensen, Charlotte Lauridsen. Redox balance and immunity of piglets pre- and post-E. coli challenge after treatment with hemp or fish oil, and vitamin E. Scientific reports. 2024 05; 14(1):11053. doi: 10.1038/s41598-024-61927-1. [PMID: 38744900]
  • Jooyeoun Jung, Caroline Christandi Loe, Yanyun Zhao. Development and characterization of cranberry pomace extract incorporated and vitamin E fortified edible films as an edible separation sheet for fruit leather. Journal of food science. 2024 May; 89(5):2857-2866. doi: 10.1111/1750-3841.17039. [PMID: 38532702]
  • N I M Hemly, N N Zainudin, A I Muhammad, T C Loh, A A Samsudin. Effects of supplementation of different selenium sources on lipid profile, selenium, and vitamin E concentration of yolk. Tropical animal health and production. 2024 May; 56(4):149. doi: 10.1007/s11250-024-04006-x. [PMID: 38691179]
  • Angela K Jarman, Michelle E Shaw, Sonia Y Liu, Catherine E Grueber. An insight into vitamin E and lipid nutrition of the plains-wanderer Pedionomus torquatus. Zoo biology. 2024 May; 43(3):213-223. doi: 10.1002/zoo.21815. [PMID: 38294092]
  • Melika Golmohamadi, Somayeh Hosseinpour-Niazi, Parto Hadaegh, Parvin Mirmiran, Fereidoun Azizi, Farzad Hadaegh. Association between dietary antioxidants intake and the risk of type 2 diabetes mellitus in a prospective cohort study: Tehran Lipid and Glucose Study. The British journal of nutrition. 2024 Apr; 131(8):1452-1460. doi: 10.1017/s0007114523002854. [PMID: 38116651]
  • Piotr Gębczyński, Małgorzata Tabaszewska, Katarzyna Kur, Maria Zbylut-Górska, Jacek Słupski. Effect of the Drying Method and Storage Conditions on the Quality and Content of Selected Bioactive Compounds of Green Legume Vegetables. Molecules (Basel, Switzerland). 2024 Apr; 29(8):. doi: 10.3390/molecules29081732. [PMID: 38675551]
  • Hao Tian, Yi-Fang Li, Gen-Long Jiao, Wan-Yang Sun, Rong-Rong He. Unveiling the antioxidant superiority of α-tocopherol: Implications for vitamin E nomenclature and classification. Free radical biology & medicine. 2024 Apr; 216(?):46-49. doi: 10.1016/j.freeradbiomed.2024.03.003. [PMID: 38458392]
  • Ali Honarvar, Mohsen Setayeshmehr, Sho'leh Ghaedamini, Batool Hashemibeni, Lorenzo Moroni, Saeed Karbasi. Chondrogenesis of mesenchymal stromal cells on the 3D printed polycaprolactone/fibrin/decellular cartilage matrix hybrid scaffolds in the presence of piascledine. Journal of biomaterials science. Polymer edition. 2024 Apr; 35(6):799-822. doi: 10.1080/09205063.2024.2307752. [PMID: 38289681]
  • Van-Trung-Tin Huynh, Suenia de Paiva Lacerda, Fabienne Espitalier, Eric Beyssac, Maria-Inês Ré. Effect of talc and vitamin E TPGS on manufacturability, stability and release properties of trilaurin-based formulations for hot-melt coating. International journal of pharmaceutics. 2024 Mar; 653(?):123866. doi: 10.1016/j.ijpharm.2024.123866. [PMID: 38286194]
  • Azita Sadough Shahmirzadi, Hamid Shafi, Hoda Shirafkan, Zahra Memariani, Narjes Gorji, Reihaneh Moeini. Effect of Medicago sativa seed powder (Plus vitamin E vs. vitamin E alone) on semen analysis in men with idiopathic infertility: A double blind randomized clinical trial. Journal of ethnopharmacology. 2024 Mar; 322(?):117606. doi: 10.1016/j.jep.2023.117606. [PMID: 38103848]
  • Abdelkader A Metwally, Samayita Ganguly, Nora Biomi, Mingyi Yao, Tamer Elbayoumi. Cationic Vitamin E-TPGS Mixed Micelles of Berberine to Neutralize Doxorubicin-Induced Cardiotoxicity via Amelioration of Mitochondrial Dysfunction and Impeding Apoptosis. Molecules (Basel, Switzerland). 2024 Mar; 29(5):. doi: 10.3390/molecules29051155. [PMID: 38474668]
  • Tanvi Patel, Kimberly McBennett, Senthilkumar Sankararaman, Teresa Schindler, Krithika Sundaram, Nori Mercuri Minich, Sindhoosha Malay, Katherine Kutney. Impact of elexacaftor/tezacaftor/ivacaftor on lipid and fat-soluble vitamin levels and association with body mass index. Pediatric pulmonology. 2024 Mar; 59(3):734-742. doi: 10.1002/ppul.26823. [PMID: 38179878]
  • Nirdesh Kumar, Ashmita Das, Nidhi Kumari, Geeta Singh, Urvashi Jain, Amrita Singh, Surendra H Bodakhe. Intermittent Fasting and Vitamin E Supplementation Attenuates Hypothyroidism-Associated Ophthalmopathy. Molecular nutrition & food research. 2024 Mar; 68(5):e2300589. doi: 10.1002/mnfr.202300589. [PMID: 38342593]
  • Paula Muñoz, Verónica Tijero, Celia Vincent, Sergi Munné-Bosch. Abscisic acid triggers vitamin E accumulation by transient transcript activation of VTE5 and VTE6 in sweet cherry fruits. The Biochemical journal. 2024 Feb; ?(?):. doi: 10.1042/bcj20230399. [PMID: 38314636]
  • Liana Trugilho, Livia Alvarenga, Ludmila Fmf Cardozo, Isis Barboza, Maurilo Leite, Denis Fouque, Denise Mafra. Vitamin E and conflicting understandings in noncommunicable diseases: Is it worth supplementing?. Clinical nutrition ESPEN. 2024 Feb; 59(?):343-354. doi: 10.1016/j.clnesp.2023.12.147. [PMID: 38220396]
  • M A G Quaresma, F Abade Dos Santos, L C Roseiro, A P Ribeiro, J D Ferreira, S P Alves, R J B Bessa. Nutritional value of meat lipid fraction obtained from mallard duck (Anas platyrhynchos) reared in semiextensive conditions for hunting purposes. Poultry science. 2024 Feb; 103(2):103290. doi: 10.1016/j.psj.2023.103290. [PMID: 38100942]
  • Xiangjun Qi, Jiayun Guo, Yanlong Li, Caishan Fang, Jietao Lin, Xueqing Chen, Jie Jia. Vitamin E intake is inversely associated with NAFLD measured by liver ultrasound transient elastography. Scientific reports. 2024 01; 14(1):2592. doi: 10.1038/s41598-024-52482-w. [PMID: 38296998]
  • Xiaoran Zhao, Qi Xu, Qian Wang, Xingxing Liang, Jing Wang, Hongwei Jin, Yizhi Man, Dongyang Guo, Feng Gao, Xinjing Tang. Induced Self-Assembly of Vitamin E-Spermine/siRNA Nanocomplexes via Spermine/Helix Groove-Specific Interaction for Efficient siRNA Delivery and Antitumor Therapy. Advanced healthcare materials. 2024 Jan; ?(?):e2303186. doi: 10.1002/adhm.202303186. [PMID: 38234201]
  • Huawei Wei, Zuqing Yang, Sylvain Niyitanga, Aifen Tao, Jiantang Xu, Pingping Fang, Lihui Lin, Liemei Zhang, Jianmin Qi, Ray Ming, Liwu Zhang. The reference genome of seed hemp (Cannabis sativa) provides new insights into fatty acid and vitamin E synthesis. Plant communications. 2024 Jan; 5(1):100718. doi: 10.1016/j.xplc.2023.100718. [PMID: 37717143]
  • Xin Jin, Hangyi Wu, Jie Yu, Yanni Cao, Lanyi Zhang, Zhenhai Zhang, Huixia Lv. Glutamate affects self-assembly, protein corona, and anti-4 T1 tumor effects of melittin/vitamin E-succinic acid-(glutamate)n nanoparticles. Journal of controlled release : official journal of the Controlled Release Society. 2024 Jan; 365(?):802-817. doi: 10.1016/j.jconrel.2023.12.013. [PMID: 38092255]
  • Chikako Kiyose. Anti-inflammatory Effects of Food Ingredients on Mice Adipose Tissues and Adipocytes. Journal of oleo science. 2024; 73(4):411-418. doi: 10.5650/jos.ess23221. [PMID: 38556276]
  • Roseani da Silva Andrade, Fabíola Isabel Suano de Souza, Carolina Sanchez Aranda, Marcia Carvalho Mallozi, Ariel Cordeiro Ferreira, Talita Lemos Neves Barreto, Fernando Luiz Affonso Fonseca, Roseli Oselka Saccardo Sarni, Dirceu Solé. Antioxidant defense of children and adolescents with atopic dermatitis: Association with disease severity. Allergologia et immunopathologia. 2024; 52(1):65-70. doi: 10.15586/aei.v52i1.933. [PMID: 38186195]
  • Ganesh Diwakar, Lisa Barnes, Melanie Riggs, Helen Knaggs, Zoe Diana Draelos. Plant-Derived Extracts Plus Vitamin E and/or Aloe Vera Protect Against Intrinsic/Extrinsic Stressor in Human Skin: In Vitro and Clinical Evidence. Frontiers in bioscience (Landmark edition). 2023 Dec; 28(12):366. doi: 10.31083/j.fbl2812366. [PMID: 38179774]
  • Jill Romer, Katharina Gutbrod, Antonia Schuppener, Michael Melzer, Stefanie J Müller-Schüssele, Andreas J Meyer, Peter Dörmann. Tocopherol and phylloquinone biosynthesis in chloroplasts requires the phytol kinase VTE5 and the farnesol kinase FOLK. The Plant cell. 2023 Dec; ?(?):. doi: 10.1093/plcell/koad316. [PMID: 38124486]
  • Baiyun Zhao, Jing Zhang, Kaiyue Zhao, Wenbin Zhao, Yajuan Shi, Jing Liu, Ling Zeng, Chaoxuan Wang, Xin Zeng, Junping Shi. Study on the mechanism of vitamin E alleviating non-alcoholic fatty liver function based on non-targeted metabolomics analysis in rats. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Dec; ?(?):. doi: 10.1007/s00210-023-02864-0. [PMID: 38091076]
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