4-Hydroxycinnamic acid (BioDeep_00000000110)

 

Secondary id: BioDeep_00000264834, BioDeep_00000400134, BioDeep_00000400283, BioDeep_00000409755, BioDeep_00000419015, BioDeep_00000859939

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


(E)-3-(4-hydroxyphenyl)prop-2-enoic acid

化学式: C9H8O3 (164.0473418)
中文名称: 对羟基肉桂酸, 对香豆酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 4-羟基肉桂酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸, 对香豆酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.02%

Reviewed

Last reviewed on 2024-09-04.

Cite this Page

4-Hydroxycinnamic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/4-hydroxycinnamic_acid (retrieved 2024-11-05) (BioDeep RN: BioDeep_00000000110). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=CC=C1C=CC(=O)O)O
InChI: InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)

描述信息

4-Hydroxycinnamic acid, also known as p-Coumaric acid, is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate. p-coumaric acid is an organic compound that is a hydroxy derivative of cinnamic acid. There are three isomers of coumaric acid: o-coumaric acid, m-coumaric acid, and p-coumaric acid, that differ by the position of the hydroxy substitution of the phenyl group. p-Coumaric acid is the most abundant isomer of the three in nature. p-Coumaric acid exists in two forms trans-p-coumaric acid and cis-p-coumaric acid. It is a crystalline solid that is slightly soluble in water, but very soluble in ethanol and diethyl ether. 4-Hydroxycinnamic acid belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. 4-Hydroxycinnamic acid exists in all living species, ranging from bacteria to humans. Outside of the human body, 4-Hydroxycinnamic acid is found, on average, in the highest concentration within a few different foods, such as pepper (Capsicum frutescens), pineapples, and sunflowers and in a lower concentration in spinachs, kiwis, and sweet oranges. 4-Hydroxycinnamic acid has also been detected, but not quantified in several different foods, such as wild rices, soursops, garden onions, hyssops, and avocado.
4-coumaric acid is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate.
4-Hydroxycinnamic acid is a natural product found in Ficus septica, Visnea mocanera, and other organisms with data available.
trans-4-Coumaric acid is a metabolite found in or produced by Saccharomyces cerevisiae.
See also: Black Cohosh (part of); Galium aparine whole (part of); Lycium barbarum fruit (part of) ... View More ...
Coumaric acid is a hydroxycinnamic acid, an organic compound that is a hydroxy derivative of cinnamic acid. There are three isomers, o-coumaric acid, m-coumaric acid, and p-coumaric acid, that differ by the position of the hydroxy substitution of the phenyl group. p-Coumaric acid is the most abundant isomer of the three in nature. p-Coumaric acid is found in many foods, some of which are garden onion, turmeric, green bell pepper, and common thyme.
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
D000975 - Antioxidants > D016166 - Free Radical Scavengers
D020011 - Protective Agents > D000975 - Antioxidants
The trans-isomer of 4-coumaric acid.
D000890 - Anti-Infective Agents
Acquisition and generation of the data is financially supported in part by CREST/JST.
CONFIDENCE standard compound; INTERNAL_ID 168
KEIO_ID C024
p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.
p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.

p-Coumaric acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=7400-08-0 (retrieved 2024-09-04) (CAS RN: 7400-08-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

122 个代谢物同义名

InChI=1/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3; (E)-3-(4-hydroxyphenyl)prop-2-enoate;Trans-4-Hydroxycinnamic Acid; p-Coumaric acid, primary pharmaceutical reference standard; Dehydroepiandrosterone-[D6] (CertiMass solution); 2-propenoic acid, 3-(4-hydroxyphenyl)-, (2E)-; 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)-; 4-10-00-01005 (Beilstein Handbook Reference); 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (Z)-; 0-10-00-00297 (Beilstein Handbook Reference); (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid #; trans-3-(4-Hydroxyphenyl)-2-propenoic acid; trans-3-(4-hydroxyphenyl)-2-propenoic acid; trans-p-Coumaric acid, analytical standard; (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid; (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid; (E)-3-[4-hydroxyphenyl]-2-propenoic acid; (E)-3-(4-hydroxyphenyl)prop-2-enoic acid; (E)-3-(4-Hydroxyphenyl)-2-propenoic acid; (E)-3-(4-hydroxyphenyl)prop-2-enoicacid; 2-Propenoic acid, 3-(4-hydroxyphenyl)-; p-Coumaric acid;p-Hydroxycinnamic acid; .BETA.-(4-HYDROXYPHENYL)ACRYLIC ACID; 0C1BFF2D-2CF7-4FC1-9F76-3268C2C7F783; (2E)-3-(4-hydroxyphenyl)acrylic acid; .beta.-[4-Hydroxyphenyl]acrylic acid; 3-(4-hydroxyphenyl)prop-2-enoic acid; (E)-3-(4-hydroxyphenyl)prop-2-enoate; 3-(4-Hydroxyphenyl)-2-propenoic acid; (e)-3-(4-Hydroxyphenyl)-2-propenoate; (E)-3-(4-Hydroxyphenyl)acrylic acid; beta-[4-Hydroxyphenyl]acrylic acid; beta-(4-Hydroxyphenyl)acrylic acid; phenol, 4-(3-hydroxy-1-propenyl)-; trans-p-HydroxyzimtsA currencyure; Cinnamic acid, 4-hydroxy-, trans-; p-Coumaric acid, >=98.0\\% (HPLC); 3-(4-Hydroxyphenyl)-2-propenoate; (2E)-3-(4-Hydroxyphenyl)acrylate; b-[4-Hydroxyphenyl]acrylic acid; 3-(4-hydroxyphenyl)acrylic acid; Cinnamic acid, p-hydroxy-, (E)-; β-[4-Hydroxyphenyl]acrylic acid; beta-[4-Hydroxyphenyl]acrylate; 4-coumaric acid, disodium salt; p-Hydroxy-trans-cinnamic acid; 4-HYDROXYPHENYLPROPENOIC ACID; p-Hydroxycinnamic acid, trans; trans-4-Hydroxycinnamic acid; trans-p-Hydroxycinnamic acid; HYDROXYCINNAMIC ACID [INCI]; trans-4-HydroxycinnamicAcid; p-Hydroxyphenylacrylic acid; p-hydroxycinnamic acid (M4); 3-(4-hydroxyphenyl)acrylate; 4-coumaric acid, (E)-isomer; b-[4-Hydroxyphenyl]acrylate; 4-coumaric acid, (Z)-isomer; (E)-p-Hydroxycinnamic acid; (E)-4-hydroxycinnamic acid; 4-Hydroxyphenylpropenoate; Cinnamic acid, p-hydroxy-; PARA HYDROXYCINNAMIC ACID; trans-4-hydroxycinnamate; P-COUMARIC ACID [WHO-DD]; trans-p-Hydroxycinnamate; SODIUM2,4-PENTANEDIONATE; parahydroxycinnamic acid; 4-hydroxy cinnamic acid; trans-p-Coumarinic acid; p-Hydroxy-cinnamic acid; P-Hydroxyphenylacrylate; 4’-Hydroxycinnamic acid; (e)-p-Hydroxycinnamate; 4-hydroxycinnamic acid; p-Coumaric acid, trans; p-hydroxycinnamic acid; 4-Hydroxycinamic acid; trans-p-Coumaric acid; p-Coumaric acid,trans; 4-Hydroxycinnamicacid; p-trans-Coumaric acid; trans-4-coumaric acid; P-COUMARIC ACID [MI]; trans-p-Cumaric Acid; p-Coumaric acid 98\\%; Hydroxycinnamic acid; 4-Hydroxy cinnamate; (E)-p-Coumaric acid; trans-p-Coumarinate; p-Hydroxy-cinnamic; p-Hydroxycinnamate; p-coumaryl alcohol; para-coumaric acid; 4-Hydroxycinnamate; Para coumaric acid; trans-p-coumarate; Naringeninic acid; trans-4-Coumarate; Coumaric acid, p-; naringeninic-acid; hydroxycinnamate; p-Coumaric acid; UNII-IBS9D1EU3J; 4-coumaric acid; (e)-p-Coumarate; cis-P-Coumarate; p-coumaric-acid; Para coumarate; p-Cumaric acid; Para-Coumarate; Naringeninate; Coumaric acid; 4-coumarate; ORISTAR PCA; p-coumarate; IBS9D1EU3J; p-Cumarate; trans-HPPA; p-Coumaric; 4qem; 4f8j; 4-Hydroxycinnamic acid



数据库引用编号

59 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

205 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(2)

Plant Reactome(198)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(4)

  • Flavanone Biosynthesis: 4-Hydroxycinnamic acid + Adenosine triphosphate + Coenzyme A ⟶ 4-Coumaroyl-CoA + Adenosine monophosphate + Pyrophosphate
  • Flavin Biosynthesis: 5-Amino-6-(5'-phosphoribosylamino)uracil + Hydrogen Ion + NADPH ⟶ 5-Amino-6-(5'-phosphoribitylamino)uracil + NADP
  • Flavin Biosynthesis: Adenosine triphosphate + Riboflavin ⟶ Adenosine diphosphate + Flavin Mononucleotide + Hydrogen Ion
  • Riboflavin Metabolism: Adenosine triphosphate + Riboflavin ⟶ Adenosine diphosphate + Flavin Mononucleotide

PharmGKB(0)

610 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Vahid Karimzadegan, Manoj Koirala, Sajjad Sobhanverdi, Natacha Merindol, Bharat Bhusan Majhi, Sarah-Eve Gélinas, Vitaliy I Timokhin, John Ralph, Mehran Dastmalchi, Isabel Desgagné-Penix. Characterization of cinnamate 4-hydroxylase (CYP73A) and p-coumaroyl 3'-hydroxylase (CYP98A) from Leucojum aestivum, a source of Amaryllidaceae alkaloids. Plant physiology and biochemistry : PPB. 2024 May; 210(?):108612. doi: 10.1016/j.plaphy.2024.108612. [PMID: 38598867]
  • Samet Tekin, Emin Sengul, Serkan Yildirim, Emrah Hicazi Aksu, İsmail Bolat, Burak Çınar, Azizeh Shadidizaji, Fikret Çelebi, Mohamad Warda. Molecular insights into the antioxidative and anti-inflammatory effects of P-coumaric acid against bisphenol A-induced testicular injury: In vivo and in silico studies. Reproductive toxicology (Elmsford, N.Y.). 2024 Apr; 125(?):108579. doi: 10.1016/j.reprotox.2024.108579. [PMID: 38513920]
  • Stanely Mainzen Prince Ponnian, Shervin Prince Stanely, Abhro Jyoti Roy. Cardioprotective effects of p-coumaric acid on tachycardia, inflammation, ion pump dysfunction, and electrolyte imbalance in isoproterenol-induced experimental myocardial infarction. Journal of biochemical and molecular toxicology. 2024 Mar; 38(3):e23668. doi: 10.1002/jbt.23668. [PMID: 38439645]
  • Cem Baltacıoğlu, Hande Baltacıoğlu, İlhami Okur, Mehmet Yetişen, Hami Alpas. Recovery of phenolic compounds from peach pomace using conventional solvent extraction and different emerging techniques. Journal of food science. 2024 Mar; 89(3):1672-1683. doi: 10.1111/1750-3841.16972. [PMID: 38343298]
  • Jiang-Yan Chen, Sheng Guo, Xiao-Xue Xu, Ya Yang, Yue Zhu, Hong-Jie Kang, Jin-Ao Duan. [Comparison of in vivo pharmacokinetics of twelve constituents in Qihe Fenqing Yin in normal rats and diabetic rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Mar; 49(5):1378-1387. doi: 10.19540/j.cnki.cjcmm.20231210.201. [PMID: 38621986]
  • Faezeh Khosravi, Samin Mohammadi, Morteza Kosari-Nasab, Parina Asgharian. The impact of microcrystalline and nanocrystalline cellulose on the antioxidant phenolic compounds level of the cultured Artemisia absinthium. Scientific reports. 2024 02; 14(1):2692. doi: 10.1038/s41598-023-50772-3. [PMID: 38302508]
  • Feixiang Chen, Xinxin Zhang, Junxiang Wang, Fukai Wang, Jinlong Mao. P-Coumaric Acid: Advances in Pharmacological Research Based on Oxidative Stress. Current topics in medicinal chemistry. 2024 Jan; ?(?):. doi: 10.2174/0115680266276823231230183519. [PMID: 38279744]
  • Arun Kumar, Narpinder Singh, Robin Joshi. Deciphering the metabolic signatures of Trigonella microgreens as a function of photoperiod and temperature using targeted compound analysis and non-targeted UHPLC-QTOF-IMS based approach. Food research international (Ottawa, Ont.). 2024 Jan; 176(?):113834. doi: 10.1016/j.foodres.2023.113834. [PMID: 38163730]
  • Yalda Sabaghi, Farnaz PourFarzad, Leila Zolghadr, Azita Bahrami, Tahereh Shojazadeh, Alireza Farasat, Nematollah Gheibi. A nano-liposomal carrier containing p-coumaric acid for induction of targeted apoptosis on melanoma cells and kinetic modeling. Biochemical and biophysical research communications. 2024 Jan; 690(?):149219. doi: 10.1016/j.bbrc.2023.149219. [PMID: 37995451]
  • Bing Cao, Meng-Nan Zeng, Feng-Xiao Hao, Zhi-You Hao, Zhen-Kai Zhang, Xi-Wen Liang, Yuan-Yuan Wu, Yu-Han Zhang, Wei-Sheng Feng, Xiao-Ke Zheng. P-coumaric acid ameliorates Aβ25-35-induced brain damage in mice by modulating gut microbiota and serum metabolites. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Dec; 168(?):115825. doi: 10.1016/j.biopha.2023.115825. [PMID: 37924791]
  • Mario Mutz, Dominic Kösters, Benedikt Wynands, Nick Wierckx, Jan Marienhagen. Microbial synthesis of the plant natural product precursor p-coumaric acid with Corynebacterium glutamicum. Microbial cell factories. 2023 Oct; 22(1):209. doi: 10.1186/s12934-023-02222-y. [PMID: 37833813]
  • Manas Kinra, Niraja Ranadive, Madhavan Nampoothiri, Devinder Arora, Jayesh Mudgal. Involvement of NLRP3 inflammasome pathway in the protective mechanisms of ferulic acid and p-coumaric acid in LPS-induced sickness behavior and neuroinflammation in mice. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Sep; ?(?):. doi: 10.1007/s00210-023-02743-8. [PMID: 37755515]
  • Rizwan Khan, Imrana Naseem. Antiglycation, antifibrillation and antioxidative effects of para coumaric acid and vitamin D; an in-vitro and in-silico comparative-cum-synergistic approach. Biochimica et biophysica acta. General subjects. 2023 Sep; ?(?):130455. doi: 10.1016/j.bbagen.2023.130455. [PMID: 37678652]
  • Jiwei Mao, Marta Tous Mohedano, Jing Fu, Xiaowei Li, Quanli Liu, Jens Nielsen, Verena Siewers, Yun Chen. Fine-tuning of p-coumaric acid synthesis to increase (2S)-naringenin production in yeast. Metabolic engineering. 2023 Aug; 79(?):192-202. doi: 10.1016/j.ymben.2023.08.003. [PMID: 37611820]
  • Selvaraj Nivetha, Kumaraswami Radha Thayammal Asha, Subramani Srinivasan, Raju Murali, Ambothi Kanagalakshmi. Hepatoprotective effect of p-Coumaric acid against KBrO3 -induced apoptosis in HepG2 cells. Cell biochemistry and function. 2023 Aug; ?(?):. doi: 10.1002/cbf.3837. [PMID: 37573567]
  • Jorge A Cortes-Morales, Alejandro Zamilpa, David O Salinas-Sánchez, Manasés González-Cortazar, Daniel Tapia-Maruri, Pedro Mendoza-de Gives, Juan M Rivas-González, Agustín Olmedo-Juárez. In vitro ovicidal effect of p-coumaric acid from Acacia bilimekii aerial parts against Haemonchus contortus. Veterinary parasitology. 2023 Aug; 320(?):109971. doi: 10.1016/j.vetpar.2023.109971. [PMID: 37331171]
  • Farkhondeh Safari, Hamid Hassanpour, Ahmad Alijanpour. Evaluation of hackberry (Celtis australis L.) fruits as sources of bioactive compounds. Scientific reports. 2023 07; 13(1):12233. doi: 10.1038/s41598-023-39421-x. [PMID: 37507445]
  • David Fernando Dos Santos, Vandressa Alves, Edlaine Costa, André Martins, Alexia Flavia França Vieira, Gustavo Henrique Fidelis Dos Santos, Cátia Tavares Dos Passos Francisco, Vânia Zanella Pinto. Yerba Mate (Ilex paraguariensis) Processing and Extraction: Retention of Bioactive Compounds. Plant foods for human nutrition (Dordrecht, Netherlands). 2023 Jul; ?(?):. doi: 10.1007/s11130-023-01082-6. [PMID: 37466823]
  • Shi-Hui Lu, Xiao-Na Liang, Xiao-Jin Nong, Ran Chen, Xiu-Xia Li. A New HPLC-UV Method Using Hydrolyzation with Sodium Hydroxide for Quantitation of Trans-p-Hydroxycinnamic Acid and Total Trans-p-Hydroxycinnamic Acid Esters in the Leaves of Ligustrum robustum. Molecules (Basel, Switzerland). 2023 Jul; 28(14):. doi: 10.3390/molecules28145309. [PMID: 37513183]
  • Kateryna Kukil, Elias Englund, Nick Crang, Elton P Hudson, Pia Lindberg. Laboratory evolution of Synechocystis PCC6803 for phenylpropanoid production. Metabolic engineering. 2023 Jun; ?(?):. doi: 10.1016/j.ymben.2023.06.014. [PMID: 37392984]
  • Zhiyi Yuan, Xi Lu, Fan Lei, Hong Sun, Jingfei Jiang, Dongming Xing, Lijun Du. Novel Effect of p-Coumaric Acid on Hepatic Lipolysis: Inhibition of Hepatic Lipid-Droplets. Molecules (Basel, Switzerland). 2023 Jun; 28(12):. doi: 10.3390/molecules28124641. [PMID: 37375195]
  • Elisa Bernklau, H S Arathi. Seasonal patterns of beneficial phytochemical availability in honey and stored pollen from honey bee colonies in large apiaries. Journal of economic entomology. 2023 May; ?(?):. doi: 10.1093/jee/toad096. [PMID: 37247384]
  • Li-Chao Zhang, Ya-Ning Liu, Xiao-Qin La, Shuai-Tao Li, Li-Na Wen, Ting Liu, Han-Qing Li, Ai-Ping Li, Haitao Wu, Chang-Xin Wu, Zhuo-Yu Li. The bound polyphenols of foxtail millet (Setaria italica) inner shell inhibit breast cancer by promoting lipid accumulation-induced autophagic death. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 May; ?(?):113855. doi: 10.1016/j.fct.2023.113855. [PMID: 37230459]
  • Ana González Moreno, Jack M Woolley, Eva Domínguez, Abel de Cózar, Antonio Heredia, Vasilios G Stavros. Synergic photoprotection of phenolic compounds present in tomato fruit cuticle: a spectroscopic investigation in solution. Physical chemistry chemical physics : PCCP. 2023 May; ?(?):. doi: 10.1039/d3cp00630a. [PMID: 37129056]
  • Golnaz Goodarzi, Sadra Samavarchi Tehrani, Ghodratollah Panahi, Arash Bahramzadeh, Reza Meshkani. Combination Therapy of Metformin and p-Coumaric Acid Mitigates Metabolic Dysfunction Associated with Obesity and Non-Alcoholic Fatty Liver Disease in High-Fat Diet Obese C57BL/6 Mice. The Journal of nutritional biochemistry. 2023 Apr; ?(?):109369. doi: 10.1016/j.jnutbio.2023.109369. [PMID: 37100305]
  • Joo Young Kim, Keun Ho Cho, Shea A Keene, Thomas A Colquhoun. Altered profile of floral volatiles and lignin content by down-regulation of Caffeoyl Shikimate Esterase in Petunia. BMC plant biology. 2023 Apr; 23(1):210. doi: 10.1186/s12870-023-04203-0. [PMID: 37085749]
  • Zhu-Fa Hou, Bing-Jie Zhao, Song-Shan Liu, Wen-Jing Yi, Hong Che. [Effect of P-coumaric Acid on Apoptosis of Multiple Myeloma Cells Based on Oxidative Stress]. Zhongguo shi yan xue ye xue za zhi. 2023 Apr; 31(2):435-441. doi: 10.19746/j.cnki.issn.1009-2137.2023.02.018. [PMID: 37096516]
  • Muna Alariqi, Mohamed Ramadan, Qiongqiong Wang, Zhaoguang Yang, Xi Hui, Xinhui Nie, Amani Ahmed, Qiansi Chen, Yanyin Wang, Longfu Zhu, Xianlong Zhang, Shuangxia Jin. Cotton 4-coumarate-CoA ligase 3 enhanced plant resistance to Verticillium dahliae by promoting JA signaling mediated vascular lignification and metabolic flux. The Plant journal : for cell and molecular biology. 2023 Mar; ?(?):. doi: 10.1111/tpj.16223. [PMID: 36994650]
  • Yuxin Li, Tingting Zhang, Yuqian Kang, Peng Wang, Wengang Yu, Jian Wang, Wei Li, Xingyu Jiang, Yang Zhou. Integrated metabolome, transcriptome analysis, and multi-flux full-length sequencing offer novel insights into the function of lignin biosynthesis as a Sesuvium portulacastrum response to salt stress. International journal of biological macromolecules. 2023 Mar; 237(?):124222. doi: 10.1016/j.ijbiomac.2023.124222. [PMID: 36990407]
  • Gopika Selvakumar, Suguna Lonchin. A bio-polymeric scaffold incorporated with p-Coumaric acid enhances diabetic wound healing by modulating MMP-9 and TGF-β3 expression. Colloids and surfaces. B, Biointerfaces. 2023 Mar; 225(?):113280. doi: 10.1016/j.colsurfb.2023.113280. [PMID: 36989817]
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