Aerobactin (BioDeep_00000005864)

 

Secondary id: BioDeep_00001869178

human metabolite Endogenous Volatile Flavor Compounds


代谢物信息卡片


(2S)-2-[3-carboxy-3-({[(1S)-1-carboxy-5-(N-hydroxyacetamido)pentyl]carbamoyl}methyl)-3-hydroxypropanamido]-6-(N-hydroxyacetamido)hexanoic acid

化学式: C22H36N4O13 (564.2278766)
中文名称:
谱图信息: 最多检出来源 Macaca mulatta(otcml) 6.67%

分子结构信息

SMILES: CC(=O)N(CCCCC(C(=O)O)NC(=O)CC(CC(=O)NC(CCCCN(C(=O)C)O)C(=O)O)(C(=O)O)O)O
InChI: InChI=1S/C22H36N4O13/c1-13(27)25(38)9-5-3-7-15(19(31)32)23-17(29)11-22(37,21(35)36)12-18(30)24-16(20(33)34)8-4-6-10-26(39)14(2)28/h15-16,37-39H,3-12H2,1-2H3,(H,23,29)(H,24,30)(H,31,32)(H,33,34)(H,35,36)/t15-,16-/m0/s1

描述信息

Aerobactin is a virulence factor for enteric bacteria found occasionally in humans, and is produced by bacteria such as Enterobacter cloacae. E. cloacae is part of the normal intestinal floras of many individuals and not a primary human pathogen but has been considered to be an important cause of nosocomial infections. Aerobactin secretion in vivo could be an important step in the stages of the infection cycle during which intestine-populating opportunistic bacteria effectively colonize the gut, penetrate the mucous layer covering the intestinal villi, translocate out of intestinal lumen through the epithelial cells, and finally spread to organs within which they may survive. (PMID: 9453621, 8752377) [HMDB]
Aerobactin is a virulence factor for enteric bacteria found occasionally in humans, and is produced by bacteria such as Enterobacter cloacae. E. cloacae is part of the normal intestinal floras of many individuals and not a primary human pathogen but has been considered to be an important cause of nosocomial infections. Aerobactin secretion in vivo could be an important step in the stages of the infection cycle during which intestine-populating opportunistic bacteria effectively colonize the gut, penetrate the mucous layer covering the intestinal villi, translocate out of intestinal lumen through the epithelial cells, and finally spread to organs within which they may survive. (PMID: 9453621, 8752377).
D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents

同义名列表

6 个代谢物同义名

(2S)-2-[3-carboxy-3-({[(1S)-1-carboxy-5-(N-hydroxyacetamido)pentyl]carbamoyl}methyl)-3-hydroxypropanamido]-6-(N-hydroxyacetamido)hexanoic acid; (8S,16S)-3,12,21-Trihydroxy-2,10,14,22-tetraoxo-3,9,15,21-tetraazatricosane-8,12,16-tricarboxylic acid; (8S,16S)-3,12,21-Trihydroxy-2,10,14,22-tetraoxo-3,9,15,21-tetraazatricosane-8,12,16-tricarboxylate; SCHEMBL17480163; Aerobactin; Aerobactin



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

7 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Okhee Choi, Jaeyeong Cho, Byeongsam Kang, Yeyeong Lee, Jinwoo Kim. Negatively Regulated Aerobactin and Desferrioxamine E by Fur in Pantoea ananatis Are Required for Full Siderophore Production and Antibacterial Activity, but Not for Virulence. Applied and environmental microbiology. 2022 03; 88(6):e0240521. doi: 10.1128/aem.02405-21. [PMID: 35108090]
  • Dan-Dan Wei, Xiao-Shun Xiong, Yan-Fang Mei, Fang-Ling Du, La-Gen Wan, Yang Liu. Microbiological and Clinical Characteristics of Klebsiella pneumoniae Isolates of K57 Capsular Serotype in China. Microbial drug resistance (Larchmont, N.Y.). 2021 Mar; 27(3):391-400. doi: 10.1089/mdr.2018.0456. [PMID: 32762612]
  • Mathieu Genuini, Philippe Bidet, Jean-François Benoist, Dimitri Schlemmer, Chloé Lemaitre, André Birgy, Stéphane Bonacorsi. ShiF acts as an auxiliary factor of aerobactin secretion in meningitis Escherichia coli strain S88. BMC microbiology. 2019 12; 19(1):298. doi: 10.1186/s12866-019-1677-2. [PMID: 31847813]
  • Guili Li, Shuhong Sun, Zhong Yuan Zhao, Yunfang Sun. The pathogenicity of rmpA or aerobactin-positive Klebsiella pneumoniae in infected mice. The Journal of international medical research. 2019 Sep; 47(9):4344-4352. doi: 10.1177/0300060519863544. [PMID: 31328596]
  • Zhou Liu, Yi Gu, Xin Li, Yanyan Liu, Ying Ye, Shihe Guan, Jiabin Li. Identification and Characterization of NDM-1-producing Hypervirulent (Hypermucoviscous) Klebsiella pneumoniae in China. Annals of laboratory medicine. 2019 Mar; 39(2):167-175. doi: 10.3343/alm.2019.39.2.167. [PMID: 30430779]
  • Thomas A Russo, Ruth Olson, Ulrike MacDonald, Janet Beanan, Bruce A Davidson. Aerobactin, but not yersiniabactin, salmochelin, or enterobactin, enables the growth/survival of hypervirulent (hypermucoviscous) Klebsiella pneumoniae ex vivo and in vivo. Infection and immunity. 2015 Aug; 83(8):3325-33. doi: 10.1128/iai.00430-15. [PMID: 26056379]
  • Laura J Searle, Guillaume Méric, Ida Porcelli, Samuel K Sheppard, Sacha Lucchini. Variation in siderophore biosynthetic gene distribution and production across environmental and faecal populations of Escherichia coli. PloS one. 2015; 10(3):e0117906. doi: 10.1371/journal.pone.0117906. [PMID: 25756870]
  • Haitham Ghunaim, Marwan Abdelhamid Abu-Madi, Subhashinie Kariyawasam. Advances in vaccination against avian pathogenic Escherichia coli respiratory disease: potentials and limitations. Veterinary microbiology. 2014 Aug; 172(1-2):13-22. doi: 10.1016/j.vetmic.2014.04.019. [PMID: 24878325]
  • Jielu Ling, Haizhu Pan, Qingqing Gao, Liping Xiong, Yefei Zhou, Debao Zhang, Song Gao, Xiufan Liu. Aerobactin synthesis genes iucA and iucC contribute to the pathogenicity of avian pathogenic Escherichia coli O2 strain E058. PloS one. 2013; 8(2):e57794. doi: 10.1371/journal.pone.0057794. [PMID: 23460907]
  • Liping Xiong, Jielu Ling, Qingqing Gao, Yefei Zhou, Tiantian Li, Song Gao, Xiufan Liu. Construction of iucB and iucBiutA mutants of avian pathogenic Escherichia coli and evaluation of their pathogenicity. Veterinary microbiology. 2012 Oct; 159(3-4):420-31. doi: 10.1016/j.vetmic.2012.04.024. [PMID: 22578638]
  • Chloé Lemaître, Philippe Bidet, Edouard Bingen, Stéphane Bonacorsi. Transcriptional analysis of the Escherichia coli ColV-Ia plasmid pS88 during growth in human serum and urine. BMC microbiology. 2012 Jun; 12(?):115. doi: 10.1186/1471-2180-12-115. [PMID: 22720670]
  • Ganwu Li, Subhashinie Kariyawasam, Kelly A Tivendale, Yvonne Wannemuehler, Christa Ewers, Lothar H Wieler, Catherine M Logue, Lisa K Nolan. tkt1, located on a novel pathogenicity island, is prevalent in avian and human extraintestinal pathogenic Escherichia coli. BMC microbiology. 2012 Apr; 12(?):51. doi: 10.1186/1471-2180-12-51. [PMID: 22471764]
  • Getahun Abate, Tse-Hsien Koh, Morey Gardner, L Kristopher Siu. Clinical and bacteriological characteristics of Klebsiella pneumoniae causing liver abscess with less frequently observed multi-locus sequences type, ST163, from Singapore and Missouri, US. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi. 2012 Feb; 45(1):31-6. doi: 10.1016/j.jmii.2011.09.002. [PMID: 22138655]
  • Senthilkumar Palaniyandi, Arindam Mitra, Christopher D Herren, C Virginia Lockatell, David E Johnson, Xiaoping Zhu, Suman Mukhopadhyay. BarA-UvrY two-component system regulates virulence of uropathogenic E. coli CFT073. PloS one. 2012; 7(2):e31348. doi: 10.1371/journal.pone.0031348. [PMID: 22363626]
  • Youxiong Que, Liping Xu, Jianwei Lin, Jun Luo, Jingsheng Xu, Jin Zheng, Rukai Chen. cDNA-SRAP and its application in differential gene expression analysis: a case study in Erianthus arundinaceum. Journal of biomedicine & biotechnology. 2012; 2012(?):390107. doi: 10.1155/2012/390107. [PMID: 22778549]
  • Yeala Shaked, Hagar Lis. Disassembling iron availability to phytoplankton. Frontiers in microbiology. 2012; 3(?):123. doi: 10.3389/fmicb.2012.00123. [PMID: 22529839]
  • R H Olsen, M S Chadfield, J P Christensen, F Scheutz, H Christensen, M Bisgaard. Clonality and virulence traits of Escherichia coli associated with haemorrhagic septicaemia in turkeys. Avian pathology : journal of the W.V.P.A. 2011 Dec; 40(6):587-95. doi: 10.1080/03079457.2011.618942. [PMID: 22107093]
  • Laura Gombošová, I Lazúrová, M Zakuciová, K Curová, M Kmeťová, D Petrášová, L Siegfried. Genes of intestinal Escherichia coli and their relation to the inflammatory activity in patients with ulcerative colitis and Crohn's disease. Folia microbiologica. 2011 Sep; 56(5):367-72. doi: 10.1007/s12223-011-0051-z. [PMID: 21877213]
  • Chang-Phone Fung, Feng-Yee Chang, Jung-Chung Lin, Donald Ming-Tak Ho, Chiung-Tong Chen, Jiun-Han Chen, Kuo-Ming Yeh, Te-Li Chen, Yi-Tsung Lin, L Kristopher Siu. Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model. Laboratory investigation; a journal of technical methods and pathology. 2011 Jul; 91(7):1029-39. doi: 10.1038/labinvest.2011.52. [PMID: 21464821]
  • Joanna Mokracka, Ryszard Koczura, Lucyna Jabłońska, Adam Kaznowski. Phylogenetic groups, virulence genes and quinolone resistance of integron-bearing Escherichia coli strains isolated from a wastewater treatment plant. Antonie van Leeuwenhoek. 2011 May; 99(4):817-24. doi: 10.1007/s10482-011-9555-4. [PMID: 21293926]
  • Sierra L Hartney, Sylvie Mazurier, Teresa A Kidarsa, Maria Carolina Quecine, Philippe Lemanceau, Joyce E Loper. TonB-dependent outer-membrane proteins and siderophore utilization in Pseudomonas fluorescens Pf-5. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2011 Apr; 24(2):193-213. doi: 10.1007/s10534-010-9385-2. [PMID: 21080032]
  • Makrina Totsika, Scott A Beatson, Sohinee Sarkar, Minh-Duy Phan, Nicola K Petty, Nathan Bachmann, Marek Szubert, Hanna E Sidjabat, David L Paterson, Mathew Upton, Mark A Schembri. Insights into a multidrug resistant Escherichia coli pathogen of the globally disseminated ST131 lineage: genome analysis and virulence mechanisms. PloS one. 2011; 6(10):e26578. doi: 10.1371/journal.pone.0026578. [PMID: 22053197]
  • David Smajs, Lenka Micenková, Jan Smarda, Martin Vrba, Alena Sevčíková, Zuzana Vališová, Vladana Woznicová. Bacteriocin synthesis in uropathogenic and commensal Escherichia coli: colicin E1 is a potential virulence factor. BMC microbiology. 2010 Nov; 10(?):288. doi: 10.1186/1471-2180-10-288. [PMID: 21078157]
  • Erin C Hagan, Amanda L Lloyd, David A Rasko, Gary J Faerber, Harry L T Mobley. Escherichia coli global gene expression in urine from women with urinary tract infection. PLoS pathogens. 2010 Nov; 6(11):e1001187. doi: 10.1371/journal.ppat.1001187. [PMID: 21085611]
  • Neeraja Vajrala, Luis A Sayavedra-Soto, Peter J Bottomley, Daniel J Arp. Role of Nitrosomonas europaea NitABC iron transporter in the uptake of Fe3+-siderophore complexes. Archives of microbiology. 2010 Nov; 192(11):899-908. doi: 10.1007/s00203-010-0620-6. [PMID: 20737137]
  • L Aravind, Robson F de Souza, Lakshminarayan M Iyer. Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis. Biology direct. 2010 Aug; 5(?):48. doi: 10.1186/1745-6150-5-48. [PMID: 20678224]
  • Priscila Reina Siliano, Lillian Andrade Rocha, José Osmar Medina-Pestana, Ita Pfeferman Heilberg. The role of host factors and bacterial virulence genes in the development of pyelonephritis caused by Escherichia coli in renal transplant recipients. Clinical journal of the American Society of Nephrology : CJASN. 2010 Jul; 5(7):1290-7. doi: 10.2215/cjn.06740909. [PMID: 20448070]
  • Carla C C R de Carvalho, Pedro Fernandes. Production of metabolites as bacterial responses to the marine environment. Marine drugs. 2010 Mar; 8(3):705-27. doi: 10.3390/md8030705. [PMID: 20411122]
  • Seungok Lee, Jin Kyung Yu, Kanggyun Park, Eun-Jee Oh, Soo-Young Kim, Yeon-Joon Park. Phylogenetic groups and virulence factors in pathogenic and commensal strains of Escherichia coli and their association with blaCTX-M. Annals of clinical and laboratory science. 2010; 40(4):361-7. doi: . [PMID: 20947811]
  • Gudjon L Gunnarsson, Pernille B Brandt, Dorte Gad, Carsten Struve, Ulrik S Justesen. Monomicrobial necrotizing fasciitis in a white male caused by hypermucoviscous Klebsiella pneumoniae. Journal of medical microbiology. 2009 Nov; 58(Pt 11):1519-1521. doi: 10.1099/jmm.0.011064-0. [PMID: 19661201]
  • Oliver Mirus, Sascha Strauss, Kerstin Nicolaisen, Arndt von Haeseler, Enrico Schleiff. TonB-dependent transporters and their occurrence in cyanobacteria. BMC biology. 2009 Oct; 7(?):68. doi: 10.1186/1741-7007-7-68. [PMID: 19821963]
  • Christopher J Alteri, Erin C Hagan, Kelsey E Sivick, Sara N Smith, Harry L T Mobley. Mucosal immunization with iron receptor antigens protects against urinary tract infection. PLoS pathogens. 2009 Sep; 5(9):e1000586. doi: 10.1371/journal.ppat.1000586. [PMID: 19806177]
  • Andreas M Petersen, Eva M Nielsen, Eva Litrup, Jørn Brynskov, Hengameh Mirsepasi, Karen A Krogfelt. A phylogenetic group of Escherichia coli associated with active left-sided inflammatory bowel disease. BMC microbiology. 2009 Aug; 9(?):171. doi: 10.1186/1471-2180-9-171. [PMID: 19695087]
  • Leighton Pritchard, Hui Liu, Clare Booth, Emma Douglas, Patrice François, Jacques Schrenzel, Peter E Hedley, Paul R J Birch, Ian K Toth. Microarray comparative genomic hybridisation analysis incorporating genomic organisation, and application to enterobacterial plant pathogens. PLoS computational biology. 2009 Aug; 5(8):e1000473. doi: 10.1371/journal.pcbi.1000473. [PMID: 19696881]
  • James R Johnson, Michael A Kuskowski, Krista Owens, Connie Clabots, Randall S Singer. Virulence genotypes and phylogenetic background of fluoroquinolone-resistant and susceptible Escherichia coli urine isolates from dogs with urinary tract infection. Veterinary microbiology. 2009 Apr; 136(1-2):108-14. doi: 10.1016/j.vetmic.2008.10.006. [PMID: 19019576]
  • Rolf Reissbrodt, Walter P Hammes, Fabio dal Bello, Rita Prager, Angelika Fruth, Klaus Hantke, Alexander Rakin, Marjanca Starcic-Erjavec, Peter H Williams. Inhibition of growth of Shiga toxin-producing Escherichia coli by nonpathogenic Escherichia coli. FEMS microbiology letters. 2009 Jan; 290(1):62-9. doi: 10.1111/j.1574-6968.2008.01405.x. [PMID: 19016876]
  • Ester Sánchez, Inmaculada Nadal, Ester Donat, Carmen Ribes-Koninckx, Miguel Calabuig, Yolanda Sanz. Reduced diversity and increased virulence-gene carriage in intestinal enterobacteria of coeliac children. BMC gastroenterology. 2008 Nov; 8(?):50. doi: 10.1186/1471-230x-8-50. [PMID: 18983674]
  • Kyung-Bum Lee, Philippe De Backer, Toshihiro Aono, Chi-Te Liu, Shino Suzuki, Tadahiro Suzuki, Takakazu Kaneko, Manabu Yamada, Satoshi Tabata, Doris M Kupfer, Fares Z Najar, Graham B Wiley, Bruce Roe, Tim T Binnewies, David W Ussery, Wim D'Haeze, Jeroen Den Herder, Dirk Gevers, Danny Vereecke, Marcelle Holsters, Hiroshi Oyaizu. The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571. BMC genomics. 2008 Jun; 9(?):271. doi: 10.1186/1471-2164-9-271. [PMID: 18522759]
  • Viktoria Hancock, Aswin S Seshasayee, David W Ussery, Nicholas M Luscombe, Per Klemm. Transcriptomics and adaptive genomics of the asymptomatic bacteriuria Escherichia coli strain 83972. Molecular genetics and genomics : MGG. 2008 May; 279(5):523-34. doi: 10.1007/s00438-008-0330-9. [PMID: 18317809]
  • Shalaka Samant, Hyunwoo Lee, Mahmood Ghassemi, Juan Chen, James L Cook, Alexander S Mankin, Alexander A Neyfakh. Nucleotide biosynthesis is critical for growth of bacteria in human blood. PLoS pathogens. 2008 Feb; 4(2):e37. doi: 10.1371/journal.ppat.0040037. [PMID: 18282099]
  • Jerod A Skyberg, Timothy J Johnson, Lisa K Nolan. Mutational and transcriptional analyses of an avian pathogenic Escherichia coli ColV plasmid. BMC microbiology. 2008 Jan; 8(?):24. doi: 10.1186/1471-2180-8-24. [PMID: 18230176]
  • James R Johnson, Mark R Sannes, Cynthia Croy, Brian Johnston, Connie Clabots, Michael A Kuskowski, Jeff Bender, Kirk E Smith, Patricia L Winokur, Edward A Belongia. Antimicrobial drug-resistant Escherichia coli from humans and poultry products, Minnesota and Wisconsin, 2002-2004. Emerging infectious diseases. 2007 Jun; 13(6):838-46. doi: 10.3201/eid1306.061576. [PMID: 17553221]
  • Servane Blanvillain, Damien Meyer, Alice Boulanger, Martine Lautier, Catherine Guynet, Nicolas Denancé, Jacques Vasse, Emmanuelle Lauber, Matthieu Arlat. Plant carbohydrate scavenging through tonB-dependent receptors: a feature shared by phytopathogenic and aquatic bacteria. PloS one. 2007 Feb; 2(2):e224. doi: 10.1371/journal.pone.0000224. [PMID: 17311090]
  • Marianne Valdebenito, Alvin L Crumbliss, Günther Winkelmann, Klaus Hantke. Environmental factors influence the production of enterobactin, salmochelin, aerobactin, and yersiniabactin in Escherichia coli strain Nissle 1917. International journal of medical microbiology : IJMM. 2006 Dec; 296(8):513-20. doi: 10.1016/j.ijmm.2006.06.003. [PMID: 17008127]
  • Alessandro Bartoloni, Lucia Pallecchi, Marta Benedetti, Connie Fernandez, Yolanda Vallejos, Elisa Guzman, Ana Liz Villagran, Antonia Mantella, Chiara Lucchetti, Filippo Bartalesi, Marianne Strohmeyer, Angela Bechini, Herlan Gamboa, Hugo Rodríguez, Torkel Falkenberg, Göran Kronvall, Eduardo Gotuzzo, Franco Paradisi, Gian Maria Rossolini. Multidrug-resistant commensal Escherichia coli in children, Peru and Bolivia. Emerging infectious diseases. 2006 Jun; 12(6):907-13. doi: 10.3201/eid1206.051258. [PMID: 16707045]
  • L Cursino, D Smajs, J Smarda, R M D Nardi, J R Nicoli, E Chartone-Souza, A M A Nascimento. Exoproducts of the Escherichia coli strain H22 inhibiting some enteric pathogens both in vitro and in vivo. Journal of applied microbiology. 2006 Apr; 100(4):821-9. doi: 10.1111/j.1365-2672.2006.02834.x. [PMID: 16553738]
  • J Smarda, D Smajs, S Horynová. Incidence of lysogenic, colicinogenic and siderophore-producing strains among human non-pathogenic Escherichia coli. Folia microbiologica. 2006; 51(5):387-91. doi: 10.1007/bf02931581. [PMID: 17176757]
  • S J W McPeake, J A Smyth, H J Ball. Characterisation of avian pathogenic Escherichia coli (APEC) associated with colisepticaemia compared to faecal isolates from healthy birds. Veterinary microbiology. 2005 Oct; 110(3-4):245-53. doi: 10.1016/j.vetmic.2005.08.001. [PMID: 16150559]
  • Christa Ewers, Traute Janssen, Sabine Kiessling, Hans-C Philipp, Lothar H Wieler. Rapid detection of virulence-associated genes in avian pathogenic Escherichia coli by multiplex polymerase chain reaction. Avian diseases. 2005 Jun; 49(2):269-73. doi: 10.1637/7293-102604r. [PMID: 16094833]
  • Pamela A Olah, Julie S Sherwood, Catherine M Logue. Molecular analysis of Salmonella isolates recovered from processed Turkey carcasses. Journal of food protection. 2005 Apr; 68(4):845-9. doi: 10.4315/0362-028x-68.4.845. [PMID: 15830682]
  • M Cobeljić, B Dimić, D Opacić, Z Lepsanović, V Stojanović, S Lazić. The prevalence of Shiga toxin-producing Escherichia coli in domestic animals and food in Serbia. Epidemiology and infection. 2005 Apr; 133(2):359-66. doi: 10.1017/s0950268804003334. [PMID: 15816163]
  • Maria A R Monroy, Terezinha Knöbl, José A Bottino, Claudete S Astolfi Ferreira, Antonio J Piantino Ferreira. Virulence characteristics of Escherichia coli isolates obtained from broiler breeders with salpingitis. Comparative immunology, microbiology and infectious diseases. 2005 Jan; 28(1):1-15. doi: 10.1016/j.cimid.2004.03.001. [PMID: 15563950]
  • Kelly A Tivendale, Joanne L Allen, Carol A Ginns, Brendan S Crabb, Glenn F Browning. Association of iss and iucA, but not tsh, with plasmid-mediated virulence of avian pathogenic Escherichia coli. Infection and immunity. 2004 Nov; 72(11):6554-60. doi: 10.1128/iai.72.11.6554-6560.2004. [PMID: 15501787]
  • Joel N Maslow, Ebbing Lautenbach, Thomas Glaze, Warren Bilker, James R Johnson. Colonization with extraintestinal pathogenic Escherichia coli among nursing home residents and its relationship to fluoroquinolone resistance. Antimicrobial agents and chemotherapy. 2004 Sep; 48(9):3618-20. doi: 10.1128/aac.48.9.3618-3620.2004. [PMID: 15328142]
  • E Birosová, L Siegfried, M Kmet'ová, A Makara, A Ostró, A Gresová, P Urdzík, A Liptáková, M Molokácová, R Bártl, L Valanský. Detection of virulence factors in alpha-haemolytic Escherichia coli strains isolated from various clinical materials. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2004 Jun; 10(6):569-73. doi: 10.1111/j.1469-0691.2004.00922.x. [PMID: 15191387]
  • S Kariyawasam, B N Wilkie, C L Gyles. Resistance of broiler chickens to Escherichia coli respiratory tract infection induced by passively transferred egg-yolk antibodies. Veterinary microbiology. 2004 Mar; 98(3-4):273-84. doi: 10.1016/j.vetmic.2003.10.022. [PMID: 15036536]
  • Jerod A Skyberg, Shelley M Horne, Catherine W Giddings, Richard E Wooley, Penelope S Gibbs, Lisa K Nolan. Characterizing avian Escherichia coli isolates with multiplex polymerase chain reaction. Avian diseases. 2003 Oct; 47(4):1441-7. doi: 10.1637/7030. [PMID: 14708994]
  • Christa Ewers, Traute Janssen, Lothar H Wieler. [Avian pathogenic Escherichia coli (APEC)]. Berliner und Munchener tierarztliche Wochenschrift. 2003 Sep; 116(9-10):381-95. doi: . [PMID: 14526468]
  • L K Nolan, S M Horne, C W Giddings, S L Foley, T J Johnson, A M Lynne, J Skyberg. Resistance to serum complement, iss, and virulence of avian Escherichia coli. Veterinary research communications. 2003 Feb; 27(2):101-10. doi: 10.1023/a:1022854902700. [PMID: 12718504]
  • E C Mercado, S M Rodríguez, A L D'Antuono, A L Cipolla, A M Elizondo, C A Rossetti, R Malena, M A Méndez. Occurrence and characteristics of CS31A antigen-producing Escherichia coli in calves with diarrhoea and septicaemia in Argentina. Journal of veterinary medicine. B, Infectious diseases and veterinary public health. 2003 Feb; 50(1):8-13. doi: 10.1046/j.1439-0450.2003.00610.x. [PMID: 12710494]
  • F Vandemaele, A Assadzadeh, J Derijcke, M Vereecken, B M Goddeeris. [Avian pathogenic Escherichia coli (APEC)]. Tijdschrift voor diergeneeskunde. 2002 Oct; 127(19):582-8. doi: NULL. [PMID: 12389466]
  • Michelle D Morin, Walter J Hopkins. Identification of virulence genes in uropathogenic Escherichia coli by multiplex polymerase chain reaction and their association with infectivity in mice. Urology. 2002 Sep; 60(3):537-41. doi: 10.1016/s0090-4295(02)01766-1. [PMID: 12350513]
  • S Kariyawasam, B N Wilkie, D B Hunter, C L Gyles. Systemic and mucosal antibody responses to selected cell surface antigens of avian pathogenic Escherichia coli in experimentally infected chickens. Avian diseases. 2002 Jul; 46(3):668-78. doi: 10.1637/0005-2086(2002)046[0668:samart]2.0.co;2. [PMID: 12243531]
  • Timothy J Johnson, Catherine W Giddings, Shelley M Horne, Penelope S Gibbs, Richard E Wooley, Jerod Skyberg, Pam Olah, Ronda Kercher, Julie S Sherwood, Steven L Foley, Lisa K Nolan. Location of increased serum survival gene and selected virulence traits on a conjugative R plasmid in an avian Escherichia coli isolate. Avian diseases. 2002 Apr; 46(2):342-52. doi: 10.1637/0005-2086(2002)046[0342:loissg]2.0.co;2. [PMID: 12061643]
  • Musangu Ngeleka, Lena Brereton, Gabriel Brown, John M Fairbrother. Pathotypes of avian Escherichia coli as related to tsh-, pap-, pil-, and iuc-DNA sequences, and antibiotic sensitivity of isolates from internal tissues and the cloacae of broilers. Avian diseases. 2002 Jan; 46(1):143-52. doi: 10.1637/0005-2086(2002)046[0143:poaeca]2.0.co;2. [PMID: 11922326]
  • J S Jeffrey, L K Nolan, K H Tonooka, S Wolfe, C W Giddings, S M Horne, S L Foley, A M Lynne, J O Ebert, L M Elijah, G Bjorklund, S J Pfaff-McDonough, R S Singer, C Doetkott. Virulence factors of Escherichia cofi from cellulitis or colisepticemia lesions in chickens. Avian diseases. 2002 Jan; 46(1):48-52. doi: 10.1637/0005-2086(2002)046[0048:vfoecf]2.0.co;2. [PMID: 11922349]
  • T Knöbl, M R Baccaro, A M Moreno, T A Gomes, M A Vieira, C S Ferreira, A J Ferreira. Virulence properties of Escherichia coli isolated from ostriches with respiratory disease. Veterinary microbiology. 2001 Oct; 83(1):71-80. doi: 10.1016/s0378-1135(01)00403-5. [PMID: 11524167]
  • A G Torres, P Redford, R A Welch, S M Payne. TonB-dependent systems of uropathogenic Escherichia coli: aerobactin and heme transport and TonB are required for virulence in the mouse. Infection and immunity. 2001 Oct; 69(10):6179-85. doi: 10.1128/iai.69.10.6179-6185.2001. [PMID: 11553558]
  • S E Geerlings, E C Brouwer, W Gaastra, R Stolk, R J Diepersloot, A I Hoepelman. Virulence factors of Escherichia coli isolated from urine of diabetic women with asymptomatic bacteriuria: correlation with clinical characteristics. Antonie van Leeuwenhoek. 2001 Oct; 80(2):119-27. doi: 10.1023/a:1012263304999. [PMID: 11759045]
  • M Mellata, R Bakour, E Jacquemin, J G Mainil. Genotypic and phenotypic characterization of potential virulence of intestinal avian Escherichia coli strains isolated in Algeria. Avian diseases. 2001 Jul; 45(3):670-9. doi: . [PMID: 11569742]
  • R Podschun, A Fischer, U Ullmann. Characterisation of Hafnia alvei isolates from human clinical extra-intestinal specimens: haemagglutinins, serum resistance and siderophore synthesis. Journal of medical microbiology. 2001 Mar; 50(3):208-214. doi: 10.1099/0022-1317-50-3-208. [PMID: 11232764]
  • G Fecteau, J M Fairbrother, R Higgins, D C Van Metre, J Paré, B P Smith, C A Holmberg, S Jang. Virulence factors in Escherichia coli isolated from the blood of bacteremic neonatal calves. Veterinary microbiology. 2001 Feb; 78(3):241-9. doi: 10.1016/s0378-1135(00)00299-6. [PMID: 11165068]
  • S M Gomis, C Riddell, A A Potter, B J Allan. Phenotypic and genotypic characterization of virulence factors of Escherichia coli isolated from broiler chickens with simultaneous occurrence of cellulitis and other colibacillosis lesions. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 2001 Jan; 65(1):1-6. doi: NULL. [PMID: 11227188]
  • R Podschun, A Fischer, U Ullman. Expression of putative virulence factors by clinical isolates of Klebsiella planticola. Journal of medical microbiology. 2000 Feb; 49(2):115-119. doi: 10.1099/0022-1317-49-2-115. [PMID: 10670561]
  • M Anğ-Küçüker, O Küçükbasmaci, M Tekin, D Akbulut, O Büyükbaba-Boral, O Anğ. Serotypes, siderophore synthesis, and serum resistance of uropathogenic Klebsiella isolates. Advances in experimental medicine and biology. 2000; 485(?):237-41. doi: 10.1007/0-306-46840-9_31. [PMID: 11109111]
  • B G de Brito, D S Leite, R E Linhares, M C Vidotto. Virulence-associated factors of uropathogenic Escherichia coli strains isolated from pigs. Veterinary microbiology. 1999 Mar; 65(2):123-32. doi: 10.1016/s0378-1135(98)00277-6. [PMID: 10078596]
  • K Yuri, K Nakata, H Katae, S Yamamoto, A Hasegawa. Distribution of uropathogenic virulence factors among Escherichia coli strains isolated from dogs and cats. The Journal of veterinary medical science. 1998 Mar; 60(3):287-90. doi: 10.1292/jvms.60.287. [PMID: 9560773]
  • R Keller, M Z Pedroso, R Ritchmann, R M Silva. Occurrence of virulence-associated properties in Enterobacter cloacae. Infection and immunity. 1998 Feb; 66(2):645-9. doi: 10.1128/iai.66.2.645-649.1998. [PMID: 9453621]
  • C Svanborg, G Godaly. Bacterial virulence in urinary tract infection. Infectious disease clinics of North America. 1997 Sep; 11(3):513-29. doi: 10.1016/s0891-5520(05)70371-8. [PMID: 9378921]
  • S Glockner, W Streckel, H Struy, A Fruth, J Morenz, H Tschäpe. Further search for virulence factors encoded by Salmonella serovar-specific plasmids. Zentralblatt fur Bakteriologie : international journal of medical microbiology. 1997 Jun; 286(1):69-82. doi: 10.1016/s0934-8840(97)80079-5. [PMID: 9241803]
  • R Bollmann, A Seeburg, J Parschau, G Schönian, W Sokolowska-Köhler, E Halle, W Presber. Genotypic and phenotypic determination of five virulence markers in clinical isolates of Escherichia coli. FEMS immunology and medical microbiology. 1997 Apr; 17(4):263-71. doi: 10.1111/j.1574-695x.1997.tb01020.x. [PMID: 9143884]
  • J J Carramiñana, J Yangüela, D Blanco, C Rota, A I Agustín, A Herrera. Potential virulence determinants of Salmonella serovars from poultry and human sources in Spain. Veterinary microbiology. 1997 Mar; 54(3-4):375-83. doi: 10.1016/s0378-1135(96)01290-4. [PMID: 9100337]
  • G Blum-Oehler, J Heesemann, D Kranzfelder, F Scheutz, J Hacker. Characterization of Escherichia coli serotype O12:K1:H7 isolates from an immunocompetent carrier with a history of spontaneous abortion and septicemia. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 1997 Feb; 16(2):153-5. doi: 10.1007/bf01709475. [PMID: 9105843]
  • S Sharma, N Puri, R Gupta. Constituents of human urine alter siderophore production of Escherichia coli. Folia microbiologica. 1995; 40(5):547-50. doi: 10.1007/bf02814740. [PMID: 8763149]
  • L Siegfried, M Kmetová, H Puzová, M Molokácová, J Filka. Virulence-associated factors in Escherichia coli strains isolated from children with urinary tract infections. Journal of medical microbiology. 1994 Aug; 41(2):127-32. doi: 10.1099/00222615-41-2-127. [PMID: 7913974]
  • J Nemeth, C A Muckle, C L Gyles. In vitro comparison of bovine mastitis and fecal Escherichia coli isolates. Veterinary microbiology. 1994 Jun; 40(3-4):231-8. doi: 10.1016/0378-1135(94)90112-0. [PMID: 7941288]
  • J Harel, J Fairbrother, C Forget, C Desautels, J Moore. Virulence factors associated with F165-positive Escherichia coli strains isolated from piglets and calves. Veterinary microbiology. 1993 Dec; 38(1-2):139-55. doi: 10.1016/0378-1135(93)90081-h. [PMID: 7907450]
  • R Podschun, D Sievers, A Fischer, U Ullmann. Serotypes, hemagglutinins, siderophore synthesis, and serum resistance of Klebsiella isolates causing human urinary tract infections. The Journal of infectious diseases. 1993 Dec; 168(6):1415-21. doi: 10.1093/infdis/168.6.1415. [PMID: 7902383]
  • B J Allan, J V van den Hurk, A A Potter. Characterization of Escherichia coli isolated from cases of avian colibacillosis. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 1993 Jul; 57(3):146-51. doi: . [PMID: 8358674]
  • D C Hirsh, C Kirkham, W D Wilson. Linkage of serum resistance, aerobactin production, and resistance to antimicrobial agents on conjugal plasmids in some strains of Escherichia coli isolated from septic foals. American journal of veterinary research. 1993 Jun; 54(6):878-81. doi: NULL. [PMID: 8323056]
  • D C Hirsh, C Kirkham, W D Wilson. Characteristics of Escherichia coli isolated from septic foals. Veterinary microbiology. 1993 Feb; 34(2):123-30. doi: 10.1016/0378-1135(93)90166-5. [PMID: 8451828]
  • K Ike, K Kawahara, H Danbara, K Kume. Serum resistance and aerobactin iron uptake in avian Escherichia coli mediated by conjugative 100-megadalton plasmid. The Journal of veterinary medical science. 1992 Dec; 54(6):1091-8. doi: 10.1292/jvms.54.1091. [PMID: 1477159]
  • M Der Vartanian, B Jaffeux, M Contrepois, M Chavarot, J P Girardeau, Y Bertin, C Martin. Role of aerobactin in systemic spread of an opportunistic strain of Escherichia coli from the intestinal tract of gnotobiotic lambs. Infection and immunity. 1992 Jul; 60(7):2800-7. doi: 10.1128/iai.60.7.2800-2807.1992. [PMID: 1535341]
  • C M Dozois, J M Fairbrother, J Harel, M Bossé. pap-and pil-related DNA sequences and other virulence determinants associated with Escherichia coli isolated from septicemic chickens and turkeys. Infection and immunity. 1992 Jul; 60(7):2648-56. doi: 10.1128/iai.60.7.2648-2656.1992. [PMID: 1351879]
  • R Podschun, A Fischer, U Ullmann. Siderophore production of Klebsiella species isolated from different sources. Zentralblatt fur Bakteriologie : international journal of medical microbiology. 1992 Apr; 276(4):481-6. doi: 10.1016/s0934-8840(11)80673-0. [PMID: 1535249]
  • D le Roy, D Expert, A Razafindratsita, A Deroussent, J Cosme, C Bohuon, A Andremont. Activity and specificity of a mouse monoclonal antibody to ferric aerobactin. Infection and immunity. 1992 Mar; 60(3):768-72. doi: 10.1128/iai.60.3.768-772.1992. [PMID: 1541550]
  • P Pohl, G Daube, J Mainil, P Lintermans, A Kaeckenbeeck, E Oswald. [Virulence factors and phenotypes of sixty-one strains of Escherichia coli of bovine origin, producing cytotoxic necrotising toxin type 1 (CNF 1)]. Annales de recherches veterinaires. Annals of veterinary research. 1992; 23(1):83-91. doi: . [PMID: 1510341]
  • K Tullus, S H Jacobson, M Katouli, A Brauner. Relative importance of eight virulence characteristics of pyelonephritogenic Escherichia coli strains assessed by multivariate statistical analysis. The Journal of urology. 1991 Oct; 146(4):1153-5. doi: 10.1016/s0022-5347(17)38029-1. [PMID: 1680201]
  • V L Waters, J H Crosa. Colicin V virulence plasmids. Microbiological reviews. 1991 Sep; 55(3):437-50. doi: 10.1128/mr.55.3.437-450.1991. [PMID: 1943995]