6-Methylsalicylic acid (BioDeep_00000004966)

   

natural product


代谢物信息卡片


2-HYDROXY-6-METHYLBENZOIC ACID

化学式: C8H8O3 (152.0473)
中文名称: 2-羟基-6-甲基苯甲酸
谱图信息: 最多检出来源 Homo sapiens(plant) 8.07%

分子结构信息

SMILES: C1(C(=O)O)C(O)=CC=CC=1C
InChI: InChI=1S/C8H8O3/c1-5-3-2-4-6(9)7(5)8(10)11/h2-4,9H,1H3,(H,10,11)

描述信息

A monohydroxybenzoic acid that is salicylic acid in which the hydrogen ortho to the carboxylic acid group is substituted by a methyl group.
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates

同义名列表

4 个代谢物同义名

6-Methylsalicylic acid; 2-HYDROXY-6-METHYLBENZOIC ACID; 6MSA; 6-Methylsalicylate



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

79 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ACMSD, AQP3, AQP7, AQP9, AXIN2, BTK, CDK16, FASN, HSD17B4, IRS1, MLYCD, PC, PIK3R6
Peripheral membrane protein 4 BTK, CDK16, HSD17B6, PIK3R6
Nucleus 5 AXIN2, BTK, CDK16, IRS1, PRM1
cytosol 13 ACMSD, AXIN2, BTK, CDK16, FASN, HSD17B4, IRS1, MLYCD, OXSM, PC, PIK3R6, PRM1, PXN
centrosome 1 AXIN2
nucleoplasm 4 AQP3, ATP2B1, IRS1, PRM1
Cell membrane 7 AQP3, AQP7, AQP9, ATP2B1, BTK, CDK16, PIK3R6
Cytoplasmic side 1 CDK16
lamellipodium 1 PXN
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 4 AQP3, AQP7, AQP9, ATP2B1
Synapse 1 ATP2B1
cell cortex 3 AQP7, AQP9, PXN
glutamatergic synapse 1 ATP2B1
Golgi apparatus 2 ATRN, FASN
presynaptic membrane 1 ATP2B1
synaptic vesicle 1 CDK16
Cytoplasmic vesicle, secretory vesicle 1 CDK16
plasma membrane 12 AQP3, AQP7, AQP9, ATP2B1, ATRN, AXIN2, BTK, CDK16, FASN, IRS1, PIK3R6, PXN
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ACMSD, AQP3, AQP7, AQP9, ATP2B1, FASN, HSD17B4, PIK3R6
basolateral plasma membrane 4 AQP3, AQP7, AQP9, ATP2B1
caveola 1 IRS1
extracellular exosome 3 ATP2B1, ATRN, FASN
Lumenal side 1 HSD17B6
endoplasmic reticulum 1 HSD17B6
extracellular space 2 ATRN, PRSS29P
perinuclear region of cytoplasm 1 BTK
mitochondrion 3 MLYCD, OXSM, PC
intracellular membrane-bounded organelle 5 AQP9, ATP2B1, HSD17B4, HSD17B6, IRS1
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 1 ATRN
Secreted 1 PRSS29P
cytoplasmic side of plasma membrane 1 CDK16
[Isoform 2]: Secreted 1 ATRN
Mitochondrion matrix 2 MLYCD, PC
mitochondrial matrix 3 MLYCD, OXSM, PC
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
beta-catenin destruction complex 1 AXIN2
cytoplasmic vesicle 1 BTK
microtubule cytoskeleton 1 CDK16
cell-cell junction 4 AQP3, AQP7, AQP9, PXN
Membrane raft 1 BTK
Cell junction, focal adhesion 1 PXN
Cytoplasm, cytoskeleton 1 PXN
focal adhesion 1 PXN
Peroxisome 2 HSD17B4, MLYCD
Peroxisome matrix 1 MLYCD
peroxisomal matrix 2 HSD17B4, MLYCD
peroxisomal membrane 1 HSD17B4
lateral plasma membrane 1 ATP2B1
neuron projection 1 CDK16
microtubule associated complex 1 PXN
cell projection 1 ATP2B1
Chromosome 1 PRM1
cytoskeleton 1 PXN
Cytoplasm, cell cortex 1 PXN
Basolateral cell membrane 3 AQP3, AQP9, ATP2B1
[Isoform 3]: Secreted 1 ATRN
Lipid droplet 2 AQP7, AQP9
Cytoplasmic vesicle membrane 2 AQP7, AQP9
Melanosome 1 FASN
Presynaptic cell membrane 1 ATP2B1
stress fiber 1 PXN
phosphatidylinositol 3-kinase complex 1 PIK3R6
phosphatidylinositol 3-kinase complex, class IA 1 PIK3R6
immunological synapse 1 ATP2B1
Synapse, synaptosome 1 CDK16
[Isoform 1]: Cell membrane 1 ATRN
nucleosome 1 PRM1
cyclin-dependent protein kinase holoenzyme complex 1 CDK16
insulin receptor complex 1 IRS1
photoreceptor ribbon synapse 1 ATP2B1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3R6
glycogen granule 1 FASN


文献列表

  • Imke Schmitt, H Thorsten Lumbsch. Ancient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungi. PloS one. 2009; 4(2):e4437. doi: 10.1371/journal.pone.0004437. [PMID: 19212443]
  • N Yalpani, D J Altier, E Barbour, A L Cigan, C J Scelonge. Production of 6-methylsalicylic acid by expression of a fungal polyketide synthase activates disease resistance in tobacco. The Plant cell. 2001 Jun; 13(6):1401-9. doi: 10.1105/tpc.13.6.1401. [PMID: 11402168]