NCBI Taxonomy: 37463
Phoma (ncbi_taxid: 37463)
found 500 associated metabolites at genus taxonomy rank level.
Ancestor: Didymellaceae
Child Taxonomies: Phoma mali, Phoma acuta, Phoma citri, Phoma aloes, Phoma obtusa, Phoma aliena, Phoma cajani, Phoma rosarum, Phoma herbarum, Phoma moricola, Phoma albiziae, Phoma violacea, Phoma sojicola, Phoma digitalis, Phoma leveillei, Phoma juglandis, Phoma schachtii, Phoma helianthi, Phoma capsularum, Phoma casuarinae, Phoma caloplacae, Phoma laundoniae, Phoma glaucispora, Phoma schneiderae, Phoma adonidicola, Phoma conidiogena, Phoma haematocycla, Phoma odoratissimi, unclassified Phoma, Phoma costaricensis, Phoma commelinicola, Phoma cruris-hominis, Phoma cf. herbarum G10, Phoma aff. macrostoma BBA 72146, Phoma cf. gardeniae UFMGCB 5855
Lovastatin
Lovastatin is a fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). It has a role as an Aspergillus metabolite, a prodrug, an anticholesteremic drug and an antineoplastic agent. It is a polyketide, a statin (naturally occurring), a member of hexahydronaphthalenes, a delta-lactone and a fatty acid ester. It is functionally related to a (S)-2-methylbutyric acid and a mevastatin. Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase, which catalyzes the conversion of HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). Prescribing of statin medications is considered standard practice following any cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects has resulted in this class becoming one of the most widely prescribed medications in North America. Lovastatin and other drugs from the statin class of medications including [atorvastatin], [pravastatin], [rosuvastatin], [fluvastatin], and [simvastatin] are considered first-line options for the treatment of dyslipidemia. Increasing use of the statin class of drugs is largely due to the fact that cardiovascular disease (CVD), which includes heart attack, atherosclerosis, angina, peripheral artery disease, and stroke, has become a leading cause of death in high-income countries and a major cause of morbidity around the world. Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD. Use of statins to target and reduce LDL levels has been shown in a number of landmark studies to significantly reduce the risk of development of CVD and all-cause mortality. Statins are considered a cost-effective treatment option for CVD due to their evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack. Evidence has shown that even for low-risk individuals (with <10\\\\% risk of a major vascular event occurring within 5 years) statins cause a 20\\\\%-22\\\\% relative reduction in major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. While all statin medications are considered equally effective from a clinical standpoint, [rosuvastatin] is considered the most potent; doses of 10 to 40mg [rosuvastatin] per day were found in clinical studies to result in a 45.8\\\\% to 54.6\\\\% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40\\\\%. Potency is thought to correlate to tissue permeability as the more lipophilic statins such as lovastatin are thought to enter endothelial cells by passive diffusion, as opposed to hydrophilic statins such as [pravastatin] and [rosuvastatin] which are taken up into hepatocytes through OATP1B1 (org... Lovastatin is a cholesterol-lowering agent that belongs to the class of medications called statins. It was the second agent of this class discovered. It was discovered by Alfred Alberts and his team at Merck in 1978 after screening only 18 compounds over 2 weeks. The agent, also known as mevinolin, was isolated from the fungi Aspergillus terreus. Research on this compound was suddenly shut down in 1980 and the drug was not approved until 1987. Interesting, Akira Endo at Sankyo Co. (Japan) patented lovastatin isolated from Monascus ruber four months before Merck. Lovastatin was found to be 2 times more potent than its predecessor, mevastatin, the first discovered statin. Like mevastatin, lovastatin is structurally similar to hydroxymethylglutarate (HMG), a substituent of HMG-Coenzyme A (HMG-CoA), a substrate of the cholesterol biosynthesis pathway via the mevalonic acid pathway. Lovastatin is a competitive inhibitor of HMG-CoA reductase with a binding affinity 20,000 times greater than HMG-CoA. Lovastatin differs structurally from mevastatin by a single methyl group at the 6 position. Lovastatin is a prodrug that is activated by in vivo hydrolysis of the lactone ring. It, along with mevastatin, has served as one of the lead compounds for the development of the synthetic compounds used today. A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain > C10AA - Hmg coa reductase inhibitors D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents D004791 - Enzyme Inhibitors > D019161 - Hydroxymethylglutaryl-CoA Reductase Inhibitors C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent C471 - Enzyme Inhibitor > C1655 - HMG-CoA Reductase Inhibitor D009676 - Noxae > D000963 - Antimetabolites CONFIDENCE standard compound; EAWAG_UCHEM_ID 3139 CONFIDENCE standard compound; INTERNAL_ID 2212 Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
2,4-Dichlorophenoxyacetic acid
2,4-D is a member of the phenoxy family of herbicides, which include:; 2,4-D is a synthetic auxin, which is a class of plant hormones. It is absorbed through the leaves and is translocated to the meristems of the plant. Uncontrolled, unsustainable growth ensues, causing stem curl-over, leaf withering, and eventual plant death. 2,4-D is typically applied as an amine salt, but more potent ester versions exist as well. 2,4-Dichlorophenoxyacetic acid (usually referred to by its abbreviation, 2,4-D) is a common systemic pesticide/herbicide used in the control of broadleaf weeds. It is one of the most widely used herbicide in the world, and the third most commonly used in North America. 2,4-D is a synthetic auxin (plant hormone), and as such it is often used in laboratories for plant research and as a supplement in plant cell culture media such as MS medium. It was a major ingredient in Agent Orange alongside its chemically similar relative, 2,4,5-T (2,4,5-trichlorophenoxyacetic acid). CONFIDENCE standard compound; INTERNAL_ID 737; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4196; ORIGINAL_PRECURSOR_SCAN_NO 4194 CONFIDENCE standard compound; INTERNAL_ID 737; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4186; ORIGINAL_PRECURSOR_SCAN_NO 4183 CONFIDENCE standard compound; INTERNAL_ID 737; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4207; ORIGINAL_PRECURSOR_SCAN_NO 4205 CONFIDENCE standard compound; INTERNAL_ID 737; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4200; ORIGINAL_PRECURSOR_SCAN_NO 4198 CONFIDENCE standard compound; INTERNAL_ID 737; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4181; ORIGINAL_PRECURSOR_SCAN_NO 4178 CONFIDENCE standard compound; INTERNAL_ID 737; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4198; ORIGINAL_PRECURSOR_SCAN_NO 4196 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8378 CONFIDENCE standard compound; EAWAG_UCHEM_ID 267 D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1].
Nobiletin
Nobiletin is a methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3 and 4 respectively. It has a role as a plant metabolite and an antineoplastic agent. It is functionally related to a flavone. Nobiletin is a natural product found in Citrus tankan, Citrus keraji, and other organisms with data available. See also: Tangerine peel (part of); Citrus aurantium fruit rind (part of). Isolated from peel of king orange (Citrus nobilis), seville orange (Citrus aurantium) and other Citrus subspecies, and the round kumquat (Fortunella japonica). Nobiletin is found in many foods, some of which are sweet bay, citrus, lemon, and grapefruit. Nobiletin is found in citrus. Nobiletin is isolated from peel of king orange (Citrus nobilis), seville orange (Citrus aurantium) and other Citrus species, and the round kumquat (Fortunella japonica A methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3 and 4 respectively. D020011 - Protective Agents > D000975 - Antioxidants Nobiletin is a poly-methoxylated flavone from the citrus peel that improves memory loss. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and has anti-inflammation and anti-cancer properties, including anti-angiogenesis, anti-proliferation, anti-metastasis and induced apoptosis[1][2][3][4]. Nobiletin is a poly-methoxylated flavone from the citrus peel that improves memory loss. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and has anti-inflammation and anti-cancer properties, including anti-angiogenesis, anti-proliferation, anti-metastasis and induced apoptosis[1][2][3][4].
aphidicolin
A tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D004791 - Enzyme Inhibitors
Gentisyl alcohol
An aromatic primary alcohol that is benzyl alcohol substituted by hydroxy groups at positions 2 and 5. CONFIDENCE Culture of Penicillium eurotium strain
6-Methylsalicylic acid
A monohydroxybenzoic acid that is salicylic acid in which the hydrogen ortho to the carboxylic acid group is substituted by a methyl group. D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
ent-8(14),15-Pimaradiene
ent-8(14),15-Pimaradiene is found in fruits. ent-8(14),15-Pimaradiene is a constituent of Aralia racemosa (American spikenard). Constituent of Aralia racemosa (American spikenard). ent-8(14),15-Pimaradiene is found in fruits.
Usnic acid
A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b. D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents relative retention time with respect to 9-anthracene Carboxylic Acid is 1.457 D000890 - Anti-Infective Agents > D000935 - Antifungal Agents relative retention time with respect to 9-anthracene Carboxylic Acid is 1.456 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.458 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.459 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.455 (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2]. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2]. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2]. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2]. Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1]. Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1].
Stemar-13-ene
Stemar-13-ene is a member of the class of compounds known as stemarane diterpenoids. Stemarane diterpenoids are diterpenoids with a structure characterized by a stemarane skeleton. Some characteristics include the bicyclic system C/D that is constituted by a bicyclo[3.2.1]octane fused to the bicyclic A/B system in a different fashion with respect to other tetracyclic diterpenes possessing the bicyclo[3.2.1]octane system. Moreover, the two contiguous quaternary carbon atoms, C(9) and C(10), are present, the former being a spirocyclic atom. Oxygenation can happen at positions C(2), C(7), C(13), C(17), C(18), and C(19). Thus, stemar-13-ene is considered to be an isoprenoid lipid molecule. Stemar-13-ene can be found in rice, which makes stemar-13-ene a potential biomarker for the consumption of this food product.
Cytochalasin B
C29H37NO5 (479.26715920000004)
An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments. D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with Kd value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.
Usnic_acid
7-Hydroxy-(S)-usnate is a member of benzofurans. Usnic acid is a natural product found in Lecanora muralis, Usnea florida, and other organisms with data available. D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D000890 - Anti-Infective Agents > D000935 - Antifungal Agents Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1]. Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1[1].
Berteroin
Berteroin is found in brassicas. Berteroin is produced by Wasabia japonica (Japanese horseradish
usnic acid
Mellein
Mellein, also known as (R)-mellein, is a member of the class of compounds known as 2-benzopyrans. 2-benzopyrans are organic aromatic compounds that 1-benzopyran, a bicyclic compound made up of a benzene ring fused to a pyran, so that the oxygen atom is at the 2-position. Mellein is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Mellein can be found in cocoa powder, which makes mellein a potential biomarker for the consumption of this food product. Mellein is a dihydroisocoumarin, a phenolic compound produced by Aspergillus ochraceus .
UsnicAcid
(-)-usnic acid is the (-)-enantiomer of usnic acid. It has a role as an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor. It is a conjugate acid of a (-)-usnic acid(2-). It is an enantiomer of a (+)-usnic acid. Usnic acid is a furandione found uniquely in lichen that is used widely in cosmetics, deodorants, toothpaste and medicinal creams as well as some herbal products. Taken orally, usnic acid can be toxic and has been linked to instances of clinically apparent, acute liver injury. (-)-Usnic acid is a natural product found in Dactylina arctica, Evernia divaricata, and other organisms with data available. The (-)-enantiomer of usnic acid. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2]. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2]. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2]. (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer activity[1]. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium[2].
Mellein
D009676 - Noxae > D011042 - Poisons > D009793 - Ochratoxins D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins CONFIDENCE isolated standard
5-Hydroxy-3-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one
Phomacin B
C25H37NO5 (431.26715920000004)
A cytochalasin isolated from a fungus Phoma sp. that has been shown to possess potent inhibitory activity against HT-29 colonic adenocarcinoma cells.
Phomacin A
C25H37NO5 (431.26715920000004)
A cytochalasin isolated from a fungus Phoma sp. that has been shown to possess potent inhibitory activity against HT-29 colonic adenocarcinoma cells.
Betaenone A
A carbotricyclic compound that is tricyclo[6.2.2.0(2,7)]dodecan-9-one which is substituted by hydroxy groups at positions 1, 4, and 11; by methyl groups at positions 4, 6, 8, and 11; by a hydroxymethylene group at position 10; and by a (2R)-butan-2-yl group at position 12 (the 1S,2S,4R,6R,7S,8R,10Z,11S,12R stereoisomer). A phytotoxin produced by Pleospora betae, the causal fungus of leaf spot disease on sugar beet.
Nobiletin
D020011 - Protective Agents > D000975 - Antioxidants Nobiletin is a poly-methoxylated flavone from the citrus peel that improves memory loss. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and has anti-inflammation and anti-cancer properties, including anti-angiogenesis, anti-proliferation, anti-metastasis and induced apoptosis[1][2][3][4]. Nobiletin is a poly-methoxylated flavone from the citrus peel that improves memory loss. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and has anti-inflammation and anti-cancer properties, including anti-angiogenesis, anti-proliferation, anti-metastasis and induced apoptosis[1][2][3][4].
DIMETHYL TEREPHTHALATE
D004785 - Environmental Pollutants > D012989 - Soil Pollutants D010575 - Pesticides > D007302 - Insect Repellents D020011 - Protective Agents D016573 - Agrochemicals CONFIDENCE standard compound; INTERNAL_ID 783; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10066; ORIGINAL_PRECURSOR_SCAN_NO 10061 CONFIDENCE standard compound; INTERNAL_ID 783; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10088; ORIGINAL_PRECURSOR_SCAN_NO 10085 CONFIDENCE standard compound; INTERNAL_ID 783; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10163; ORIGINAL_PRECURSOR_SCAN_NO 10160 CONFIDENCE standard compound; INTERNAL_ID 783; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10132; ORIGINAL_PRECURSOR_SCAN_NO 10128
barceloneic acid A
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
phomalevone A
A biaryl that is 5,5,10a,10a-tetrahydro-9H,9H-2,2-bixanthene-9,9-dione substituted by hydroxy groups at positions 1, 1, 5, 5, 8 and 8 and methyl groups at positions 3, 3, 10a and 10a. Isolated from the cultures of a Hawaiian isolate of the fungus Phoma species, it exhibits antibacterial activity.
phomalevone C
A biaryl that is 5,10a-dihydro-9H,9H-2,2-bixanthene-5,9,9(10aH)-trione substituted by hydroxy groups at positions 1, 1, 5, 8 and 8 and methyl groups at positions 3, 3, 10a and 10a. Isolated from the cultures of a Hawaiian isolate of the fungus Phoma species, it exhibits antibacterial and antifungal activities.
Phomalevone B
A member of the class of biphenyls that is 6,6-dimethylbiphenyl-2,2,4,4-tetrol which has been substituted by 3,6-dihydroxy-2-methylbenzoyl groups at positions 3 and 3. Isolated from the cultures of a Hawaiian isolate of the fungus Phoma species, it exhibits antibacterial and antifungal activities.
Topopyrone B
A naphthochromene that is 4H-naphtho[2,3-g]chromene-4,6,11-trione substituted by a chloro group at position 8, hydroxy groups at positions 5, 7 and 9 and a methyl group at position 2. It is isolated from a fungal strain Phoma sp.BAUA2861 and acts as an inhibitor of the enzyme topoisomerase I. D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059004 - Topoisomerase I Inhibitors D004791 - Enzyme Inhibitors
Topopyrone A
A naphthochromene that is 4H-naphtho[2,3-h]chromene-4,7,12-trione substituted by a chloro group at position 10, hydroxy groups at positions 5, 9 and 11 and a methyl group at position 2. It is isolated from a fungal strain Phoma sp.BAUA2861 and acts as an inhibitor of the enzyme topoisomerase I. D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059004 - Topoisomerase I Inhibitors D004791 - Enzyme Inhibitors
Lovastatin
C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain > C10AA - Hmg coa reductase inhibitors D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents D004791 - Enzyme Inhibitors > D019161 - Hydroxymethylglutaryl-CoA Reductase Inhibitors C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent C471 - Enzyme Inhibitor > C1655 - HMG-CoA Reductase Inhibitor CONFIDENCE standard compound; INTERNAL_ID 2212 D009676 - Noxae > D000963 - Antimetabolites relative retention time with respect to 9-anthracene Carboxylic Acid is 1.415 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.416 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.421 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.419 Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.
(1R)-2-chloro-1,7-dihydroxy-3,9-dimethoxy-1-methylbenzo[c]chromene-4,6-dione
2,4-dichlorophenoxyacetic acid
D010575 - Pesticides > D006540 - Herbicides D016573 - Agrochemicals 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1].
ent-8(14),15-Pimaradiene
(±)-Mellein
D009676 - Noxae > D011042 - Poisons > D009793 - Ochratoxins D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
stemar-13-ene
7-Epi-Zeaenol
A macrolide that is a C-7 epimer of zeaenol. Isolated from Fungi, it exhibits inhibitory activity against NF-kappaB.
Aphidicolin-17-monoacetate
A natural product found in Tolypocladium inflatum.
Phomacin C
C25H37NO4 (415.27224420000005)
A cytochalasin isolated from a fungus Phoma sp. that has been shown to possess potent inhibitory activity against HT-29 colonic adenocarcinoma cells.
1-isothiocyanato-6-(methylsulfanyl)hexane
A isothiocyanate that is hexane in which two of the terminal methyl hydrogens at positions 1 and 6 have been replaced by isothiocyanato and methylsulfanyl groups.
(4r,6r)-4-hydroxy-6-[(1e,4r,5e,8r,9e,11s,12r,13e,15z)-4,8,12,16-tetrahydroxy-11,13-dimethyl-15-[(2r,4s,6s)-2,4,6-trimethyloctylidene]hexadeca-1,5,9,13-tetraen-1-yl]oxan-2-one
5-acetyl-3,5-dimethoxy-2-methyl-4-(2-methylbutanoyl)cyclopent-2-en-1-one
(3s,6e,8r,12s,14s)-5,7,9-trihydroxy-8-methyl-13,16-dioxa-4-azatetracyclo[15.2.2.1³,⁶.0¹²,¹⁴]docosa-1(19),4,6,17,20-pentaen-22-one
3,5,9,13,17-pentahydroxy-20-(hydroxymethyl)-16,18,22,24,26-pentamethyloctacosa-6,10,14,18,20-pentaenoic acid
2-methoxy-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexyl 4,5-dihydroxyhex-2-enoate
5,6,16-trihydroxy-7,9,12,13-tetramethyl-14-(2-methylpropyl)-5h,6h,7h,8h,10ah,13h,13ah,14h-oxacyclododeca[2,3-d]isoindol-2-one
C25H37NO5 (431.26715920000004)
(1s,2s,7s,10s,12r)-2,6,6,13-tetramethyltetracyclo[10.3.1.0¹,¹⁰.0²,⁷]hexadec-13-ene
(2s,3r,4r,4as,5r,7r,8as)-3-[(2r)-butan-2-yl]-2,7-dihydroxy-7-(hydroxymethyl)-4-(3-hydroxypropanoyl)-2,4,5-trimethyl-hexahydronaphthalen-1-one
(8s,8ar)-3-[(2r)-butan-2-yl]-8,8a-dihydroxy-4-methyl-7,8-dihydro-1h-isochromen-6-one
1-(3,5-dimethyl-6-phenylhex-3-en-1-yl)-4,7-dihydroxy-6-[(4-hydroxy-4,6-dimethyloct-2-enoyl)oxy]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
3-[(7s,13s,21s,24r,27r)-5,8,11,14,22,25,28-heptahydroxy-24-(c-hydroxycarbonimidoylmethyl)-10,30-bis(2-hydroxyethyl)-27-[(1s)-1-hydroxyethyl]-21-(hydroxymethyl)-7-methyl-17,31-dioxo-3-(tetradecan-2-yl)-1-oxa-6,9,12,15,20,23,26,29-octaazacyclotritriaconta-5,8,11,14,22,25,28-heptaen-13-yl]propanoic acid
6-[1-(2,3-dimethyloxiran-2-yl)prop-1-en-2-yl]-4-methoxy-3-methylpyran-2-one
7,16-dihydroxy-14-methoxy-5-methyl-2,10-dioxatricyclo[10.4.0.0³,⁸]hexadeca-1(16),3,5,7,12,14-hexaen-9-one
5-hydroxy-3-[(4-hydroxy-6-methyl-2-oxopyran-3-yl)methyl]-6-{[5-(hydroxymethyl)-2,5,8a-trimethyl-1,4,4a,6,7,8-hexahydronaphthalen-1-yl]methyl}-7-oxabicyclo[4.1.0]hept-3-en-2-one
(1r)-2-[(2-hydroxyethyl)amino]-4-methoxy-1,5-dimethyl-6-oxocyclohexa-2,4-dien-1-yl (2r)-2-methylbutanoate
8-(acetyloxy)-7-ethenyl-16-hydroxy-1,7,11-trimethyl-3,15-dioxo-14-oxatetracyclo[11.2.1.0²,¹¹.0⁵,¹⁰]hexadec-4-en-12-yl acetate
4,7-dihydroxy-1-[4-hydroxy-3-(2-methyl-3-phenylpropylidene)butyl]-6-[(3-hydroxy-6-methyloctanoyl)oxy]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(2s,7r)-4,10-diacetyl-11-hydroxy-7,13-dimethoxy-2,12-dimethyl-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),10,12-triene-3,5-dione
2-{2,6-dihydroxy-7,7a-dimethyl-2h,6h,7h,7bh-naphtho[1,2-b]oxiren-1a-yl}prop-2-en-1-yl acetate
7,11,14,15-tetramethyl-3,6-dioxatetracyclo[12.4.0.0⁴,¹⁸.0⁵,⁷]octadeca-10,17-diene-4,17-diol
(1r,3r,4s,7e,11s,12s,13s)-3,4,7,11-tetramethyl-14,18-dioxatetracyclo[9.6.1.0⁴,¹⁶.0¹³,¹⁷]octadeca-7,16-diene-12,13-diol
5,13-dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadecane-2,10-dione
16-hydroxy-5,9,12,13,16-pentamethyl-4-oxatricyclo[10.3.1.0³,⁵]hexadeca-1(15),8-dien-2-one
(1r,5r)-5-hydroxy-4-methoxy-1,5-dimethyl-2,6-dioxocyclohex-3-en-1-yl (2r)-2-methylbutanoate
(2s,5s)-2-[(r)-hydroxy(4-hydroxyphenyl)methyl]-5-isopropyl-3,5-dimethoxypyrazine-2,6-diol
4-acetyl-2,7-dihydroxy-2,4,5,7-tetramethyl-3-(sec-butyl)-hexahydronaphthalen-1-one
(5s,7s,10as,13s,13as,14s,16as)-5,16-dihydroxy-7-(hydroxymethyl)-9,12,13-trimethyl-14-(2-methylpropyl)-5h,6h,7h,8h,10ah,13h,13ah,14h-oxacyclododeca[3,2-d]isoindol-2-one
C25H37NO5 (431.26715920000004)
1-(5-benzyl-4,6-dihydroxy-3-methylidenehexyl)-6-[(4,6-dimethyloct-2-enoyl)oxy]-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(13r)-13-hydroxypentadeca-6,7-dien-9,11-diynoic acid
(1s,3s,4s,5r,6r,7r)-1-[(3e)-3,5-dimethyl-6-phenylhex-3-en-1-yl]-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
C23H28O11 (480.16315380000003)
3-methyl-2-(methylamino)-n-[6,12,18-trihydroxy-14-(hydroxymethyl)-2,17-diisopropyl-10,16,20,22,26-pentamethyl-5,11,23-tris(2-methylpropyl)-3,9,15,21,24,28-hexaoxo-8-(sec-butyl)-1,4,25-trioxa-7,10,13,16,19,22-hexaazacyclooctacosa-6,12,18-trien-27-yl]pentanimidic acid
C54H96N8O14 (1080.7045635999998)
6-[(4e,6e,12e,14e)-3,9-dihydroxy-6,8,10,14,16,18-hexamethylicosa-4,6,12,14-tetraen-2-yl]-3-[3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-4-hydroxypyran-2-one
(1'r,2s,3's,4's,5r,7'r,10'r)-3'-hydroxy-10'-(hydroxymethyl)-4,4,5,14'-tetramethyl-3,9',13'-trioxo-11',12'-dithia-8',14'-diazaspiro[oxolane-2,5'-tetracyclo[8.2.2.0¹,⁸.0³,⁷]tetradecan]-4'-yl acetate
(1s,3r,5s,6s,15r,18e,21s,23s)-5,10-dihydroxy-6,12,17,17,21,27-hexamethyl-7,22,24,28-tetraoxahexacyclo[21.4.3.0¹,²³.0³,²¹.0⁶,¹⁵.0⁸,¹³]triaconta-8,10,12,18,26-pentaene-25,29-dione
(3s,5r,8z,12s,13s,14s,16r)-14,16-dihydroxy-5,9,12,13,16-pentamethyl-4-oxatricyclo[10.3.1.0³,⁵]hexadeca-1(15),8-dien-2-one
(1s,4'r)-4',5-dihydroxy-2,3-dihydrospiro[naphthalene-1,2'-oxolane]-4,5'-dione
(3s,6e,9s,12r,15s)-3-benzyl-6-ethylidene-8,11,14-trihydroxy-9-isopropyl-12,15-bis(2-methylpropyl)-1,4-dioxa-7,10,13-triazacyclopentadeca-7,10,13-triene-2,5-dione
(1s,5r,6r)-5,6-dihydroxy-3-(hydroxymethyl)-2-oxocyclohex-3-en-1-yl 3-chloro-2-hydroxybenzoate
1,6-dihydroxy-10a-(methylsulfanyl)-3-(phenylmethylidene)-5ah,6h,10h-pyrazino[1,2-a]indol-4-one
2-(4-hydroxybenzoyl)-5-isopropyl-3,5-dimethoxypyrazine-2,6-diol
(5s,8r,13s,16r)-5,13-dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadecane-2,10-dione
6-[(4,6-dimethyloct-2-enoyl)oxy]-4,7-dihydroxy-1-(3-{[(1-hydroxyethylidene)amino]methyl}-5-methyl-6-phenylhex-3-en-1-yl)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
4,6,7-trihydroxy-1-[4-hydroxy-3-(2-methyl-3-phenylpropylidene)butyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
1-(3,5-dimethyl-6-phenylhex-3-en-1-yl)-4,6,7-trihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
C23H28O11 (480.16315380000003)
(6e,8r,10r)-8-hydroxy-10-propyl-3,4,5,8,9,10-hexahydrooxecin-2-one
3-methyl-2-(methylamino)-n-[6,12,18-trihydroxy-14-(1-hydroxyethyl)-2,8,17-triisopropyl-10,16,20,22,26-pentamethyl-5,11,23-tris(2-methylpropyl)-3,9,15,21,24,28-hexaoxo-1,4,25-trioxa-7,10,13,16,19,22-hexaazacyclooctacosa-6,12,18-trien-27-yl]pentanimidic acid
C54H96N8O14 (1080.7045635999998)
(3r,3ar,4r,5s,7as)-7a-hydroxy-3-(1-hydroxy-4-methylpent-3-en-1-yl)-4-methoxy-3-methyl-hexahydro-2-benzofuran-5-yl (2e)-3-[(2r,3r)-3-methyloxiran-2-yl]prop-2-enoate
3'-hydroxy-10'-(hydroxymethyl)-4,4,5,11'-tetramethyl-3,9',12'-trioxo-13'-thia-8',11'-diazaspiro[oxolane-2,5'-tetracyclo[8.2.1.0¹,⁸.0³,⁷]tridecan]-4'-yl acetate
C20H26N2O8S (454.14097960000004)
(1'r,2s,3's,4's,5r,7'r,10'r)-3'-hydroxy-10'-(hydroxymethyl)-4,4,5,15'-tetramethyl-3,9',14'-trioxo-11',12',13'-trithia-8',15'-diazaspiro[oxolane-2,5'-tetracyclo[8.3.2.0¹,⁸.0³,⁷]pentadecan]-4'-yl acetate
10a,10'a-dimethyl 1,1',5,5',8,8'-hexahydroxy-6,6'-dimethyl-9,9'-dioxo-5h,5'h,6h,6'h,7h,8'ah-[2,2'-bixanthene]-10a,10'a-dicarboxylate
3-{hydroxy[1,3,6-trimethyl-2-(penta-1,3-dien-1-yl)-4a,5,6,7,8,8a-hexahydro-2h-naphthalen-1-yl]methylidene}-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
C25H35NO4 (413.25659500000006)
8a-hydroxy-5-[5-hydroxy-4-(oct-1-en-3-yl)-2-oxopyrrole-3-carbonyl]-4,6-dimethyl-2,3,4,4a,5,6-hexahydro-1h-naphthalene-2-carboxylic acid
C26H35NO6 (457.24642500000004)
1-(5-benzyl-6-hydroxy-3-methylhex-3-en-1-yl)-4,7-dihydroxy-6-[(4-methyloct-2-enoyl)oxy]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(2s,3s)-n-[(2s,5s,8s,11s,14s,17s,20s,23s,26r,27s)-8-[(2s)-butan-2-yl]-6,12,18-trihydroxy-14-(hydroxymethyl)-2,17-diisopropyl-10,16,20,22,26-pentamethyl-5,11,23-tris(2-methylpropyl)-3,9,15,21,24,28-hexaoxo-1,4,25-trioxa-7,10,13,16,19,22-hexaazacyclooctacosa-6,12,18-trien-27-yl]-3-methyl-2-(methylamino)pentanimidic acid
C54H96N8O14 (1080.7045635999998)
3-methyl-2-(n-methylacetamido)-n-[6,12,18-trihydroxy-14-(1-hydroxyethyl)-2,17-diisopropyl-10,16,20,22,26-pentamethyl-5,11,23-tris(2-methylpropyl)-3,9,15,21,24,28-hexaoxo-8-(sec-butyl)-1,4,25-trioxa-7,10,13,16,19,22-hexaazacyclooctacosa-6,12,18-trien-27-yl]pentanimidic acid
n-{5,8,11,17,20,21,23,25-octahydroxy-3-[1-hydroxy-2-(c-hydroxycarbonimidoyl)ethyl]-6-{1-hydroxy-2-[3-hydroxy-4-(sulfooxy)phenyl]ethyl}-15-(1-hydroxyethyl)-2,14-dioxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.0⁹,¹³]heptacosa-4,7,16,22-tetraen-18-yl}hexadecanimidic acid
C50H80N8O20S (1144.5209320000001)
(1's,2s,2's,4'r,9's,11'e,15'r)-2',20'-dihydroxy-1',3,9',13',13',18'-hexamethyl-5-oxo-8',23'-dioxaspiro[furan-2,6'-tetracyclo[13.8.0.0⁴,⁹.0¹⁷,²²]tricosane]-11',17',19',21'-tetraen-7'-ylideneacetic acid
(3r,6s)-6-(hydroxymethyl)-3-({4-[(3-methylbut-2-en-1-yl)oxy]phenyl}methyl)-3-(methylsulfanyl)-6h-pyrazine-2,5-diol
C18H24N2O4S (364.14567040000003)
3,8-dihydroxy-6-methoxy-3,4,5-trimethyl-4h-2-benzopyran-1-one
(3s,4s,5r,7s,9r,10s,13s,16r,17s,19r,23s,30r)-22-hydroxy-5,7,11,13,14,16-hexamethyl-2-oxa-21-azaheptacyclo[23.2.2.1³,¹⁰.0⁴,⁹.0¹²,¹⁶.0¹⁹,²³.0¹⁷,³⁰]triaconta-1(27),11,14,21,25,28-hexaene-18,20-dione
7-ethenyl-1,1,4a,7-tetramethyl-3,4,6,8,8a,9,10,10a-octahydro-2h-phenanthrene
methyl 3-(4-hydroxyphenyl)-2-(3-methyl-2-oxobutanamido)prop-2-enoate
8,9-dihydroxy-10-propyl-3,4,5,8,9,10-hexahydrooxecin-2-one
3-(hepta-1,3-dien-1-yl)-4-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-ene-2,5-diol
5-hydroxy-4-(methoxycarbonyl)-2,3-dimethylphenyl 3-hydroxy-5-methoxy-2,4,6-trimethylbenzoate
(1s,3s,4s,5r,6r,7r)-1-[(3e)-3,5-dimethyl-6-phenylhex-3-en-1-yl]-4,7-dihydroxy-6-{[(2e)-4-hydroxy-4,6-dimethyloct-2-enoyl]oxy}-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(1s,2r,3r,4s)-4-(chloromethyl)-4-hydroxy-2-methoxy-3-[(2r,3s)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]cyclohexyl (2e,4r,5s)-4,5-dihydroxyhex-2-enoate
C22H35ClO7 (446.20711900000003)
3',4'-dihydroxy-10'-(hydroxymethyl)-4,4,5,14'-tetramethyl-11',12'-dithia-8',14'-diazaspiro[oxolane-2,5'-tetracyclo[8.2.2.0¹,⁸.0³,⁷]tetradecane]-3,9',13'-trione
(2r,4s,6r,8ar)-8a-hydroxy-5-{5-hydroxy-4-[(3s)-oct-1-en-3-yl]-2-oxopyrrole-3-carbonyl}-4,6-dimethyl-2,3,4,4a,5,6-hexahydro-1h-naphthalene-2-carboxylic acid
C26H35NO6 (457.24642500000004)
[(2s,5s)-3,6-dihydroxy-5-({4-[(3-methylbut-2-en-1-yl)oxy]phenyl}methyl)-2,5-dihydropyrazin-2-yl]methyl acetate
3,8,9-trihydroxy-10-propyl-3,4,5,8,9,10-hexahydrooxecin-2-one
5,9,12,13-tetramethyl-2-oxo-4-oxatricyclo[10.3.1.0³,⁵]hexadeca-1(15),8-diene-16-carbaldehyde
(1s,3s,4s,5r,6r,7r)-1-[(3e)-3,5-dimethyl-6-phenylhex-3-en-1-yl]-6-{[(2e,4s,6s)-4,6-dimethyloct-2-enoyl]oxy}-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
methyl 3-(4-hydroxyphenyl)-2-methoxy-2-(3-methyl-2-oxobutanamido)-3-oxopropanoate
6-[(4e,6e,12e,14e)-3,9-dihydroxy-6,8,10,14,16,18-hexamethylicosa-4,6,12,14-tetraen-2-yl]-3-[3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-2-hydroxypyran-4-one
6-[(2r,3s,4e,6e,8r,9r,10s,12e,14z,16s,18r)-3,9-dihydroxy-6,8,10,14,16,18-hexamethylicosa-4,6,12,14-tetraen-2-yl]-3-[(2r,3s,4r,6r)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-4-hydroxypyran-2-one
(4as,7s,10as)-7-ethenyl-1,1,4a,7-tetramethyl-3,4,5,6,8,9,10,10a-octahydro-2h-phenanthrene
(3s,6z,8r,9s,12s,14s)-5,7,9-trihydroxy-8-methyl-13,16-dioxa-4-azatetracyclo[15.2.2.1³,⁶.0¹²,¹⁴]docosa-1(19),4,6,17,20-pentaen-22-one
(7s)-5,7-dihydroxy-8-methoxy-2-[(2e,4s)-4-methylhex-2-en-2-yl]-6-oxo-7-(2-oxopropyl)naphtho[1,2-b]furan-4-carbaldehyde
6-methoxy-4-phenyl-[1,1'-biphenyl]-2,2',5,5'-tetrol
(2r)-2-[(1s)-1-hydroxy-3-methylbutyl]-6-methyl-2h-[1,3]dioxolo[4,5-c]pyridin-4-ol
(3r,6z,8s,9s,10r)-3,8,9-trihydroxy-10-propyl-3,4,5,8,9,10-hexahydrooxecin-2-one
1a-(3-hydroxyprop-1-en-2-yl)-7,7a-dimethyl-2h,6h,7h,7bh-naphtho[1,2-b]oxirene-2,6-diol
(1s,3s,4s,5r,6r,7r)-4,7-dihydroxy-6-[(3-hydroxy-4,6-dimethyloctanoyl)oxy]-1-[(4s,5r)-4-hydroxy-5-methyl-3-methylidene-6-phenylhexyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
16-benzyl-13,18-dihydroxy-9,15-dimethyl-14-methylidene-3h,4h,6h,7h,8h,9h,10h,12ah,13h,15h,15ah,16h-oxacyclotetradeca[2,3-d]isoindole-2,5-dione
C29H37NO5 (479.26715920000004)
(1s,3s,4s,5r,6r,7r)-6-{[(2e,4s,6s)-4,6-dimethyloct-2-enoyl]oxy}-4,7-dihydroxy-1-{4-[(1-hydroxyethylidene)amino]-5-methyl-3-methylidene-6-phenylhexyl}-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(5s,8r,9s)-8-benzoyl-2-[(1z,3z)-1,4-dihydroxyhexa-1,3-dien-1-yl]-6,9-dihydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]nona-2,6-dien-4-one
(3r,5as,6s,10ar)-3-benzyl-1,6-dihydroxy-3,10a-bis(methylsulfanyl)-5ah,6h,10h-pyrazino[1,2-a]indol-4-one
C20H22N2O3S2 (402.10717819999996)
3-benzyl-6-ethylidene-8,11,14-trihydroxy-9-isopropyl-12,15-bis(2-methylpropyl)-1,4-dioxa-7,10,13-triazacyclopentadeca-7,10,13-triene-2,5-dione
4-methoxy-1,3-dimethyl-2,6-dioxocyclohex-3-en-1-yl 2-methylbutanoate
(3as,6s,7s,7ar)-4-[(1e)-hept-1-en-1-yl]-6,7-dihydroxy-5-(hydroxymethyl)-3a,6,7,7a-tetrahydro-1,3-benzodioxol-2-one
8-benzoyl-2-(1,4-dihydroxyhexa-1,3-dien-1-yl)-6,9-dihydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]nona-2,6-dien-4-one
(1r,5r,6r)-5-hydroxy-3-(hydroxymethyl)-7-oxabicyclo[4.1.0]hept-3-en-2-one
1-(3-ethyl-2,4-dihydroxy-6-methoxyphenyl)but-2-en-1-one
6-[hydroxy(4-hydroxyphenyl)methyl]-3-isopropyl-3,5,6-trimethoxypyrazin-2-ol
2-chloro-1,7-dihydroxy-3,9-dimethoxy-1-methylbenzo[c]chromene-4,6-dione
[(1s,2s,5r,6r,7r,10s,12r,13s)-5,13-dihydroxy-6-(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.0¹,¹⁰.0²,⁷]hexadecan-13-yl]methyl acetate
(3s,5r,8e,12s,13r,16r)-16-hydroxy-5,9,12,13,16-pentamethyl-4-oxatricyclo[10.3.1.0³,⁵]hexadeca-1(15),8-dien-2-one
(5r,7s,10z,14r,15s)-7,11,14,15-tetramethyl-3,6-dioxatetracyclo[12.4.0.0⁴,¹⁸.0⁵,⁷]octadeca-1(18),10-diene-4,17-diol
(6s,7e)-6-hydroxy-10-pentyl-3,4,5,6,9,10-hexahydrooxecin-2-one
(1s,2s,10s,12r)-2,6,6,13-tetramethyltetracyclo[10.3.1.0¹,¹⁰.0²,⁷]hexadec-13-ene
{7-hydroxy-2-[(2e,4s)-4-methylhex-2-en-2-yl]-4-oxochromen-5-yl}acetic acid
(4r,5s,6r)-6-hydroxy-5-(2-hydroxypropanoyl)-4-methylcyclohex-2-en-1-one
(1as,2r,7s,7ar,7br)-1a-(3-hydroxyprop-1-en-2-yl)-7,7a-dimethyl-2h,6h,7h,7bh-naphtho[1,2-b]oxiren-2-ol
6-[(4,6-dimethyloct-2-enoyl)oxy]-4,7-dihydroxy-1-(4-hydroxy-5-methyl-3-methylidene-6-phenylhexyl)-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(1s,3s,4s,5r,6r,7r)-1-[(4s,5r)-4-(acetyloxy)-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-[(3-hydroxy-4,6-dimethyloctanoyl)oxy]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
3'-hydroxy-10'-(hydroxymethyl)-4,4,5,15'-tetramethyl-3,9',14'-trioxo-11',12',13'-trithia-8',15'-diazaspiro[oxolane-2,5'-tetracyclo[8.3.2.0¹,⁸.0³,⁷]pentadecan]-4'-yl acetate
(3s,6e,8s,9s,10r)-8,9-dihydroxy-2-oxo-10-pentyl-3,4,5,8,9,10-hexahydrooxecin-3-yl (2e,4e)-hexa-2,4-dienoate
(4r,6s)-6-methyl-4-{[(1r,5s)-5-methyl-4-oxocyclohex-2-en-1-yl]oxy}cyclohex-2-en-1-one
(2r,3r,4ar,5r,8s,8as)-3,8a-dihydroxy-5-methoxy-4-oxo-2-propyl-hexahydro-2h-1-benzopyran-8-yl (2e,4e)-hexa-2,4-dienoate
10a,10'a-dimethyl 1,5,5',8,8'-pentahydroxy-6,6'-dimethyl-9,9'-dioxo-2',3'-dihydro-5h,5'h,6h,6'h,7h,7'h-[2,2'-bixanthene]-10a,10'a-dicarboxylate
(1r,3s,7r,13s,15e,19z,21s)-21-hydroxy-7,13,17,17,20-pentamethyl-4,8,12-trioxatetracyclo[11.9.0.0³,⁷.0³,¹¹]docosa-10,15,19-triene-5,9-dione
5-[5-(2,6-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalene-1-carbonyl)-4,6-dihydroxypyridin-3-yl]-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-one
C24H29NO6 (427.19947740000003)
(3s,6z,8s,9s,10r)-3,8,9-trihydroxy-10-propyl-3,4,5,8,9,10-hexahydrooxecin-2-one
(3s)-5,7-dihydroxy-3-[(2r,3s)-3-hydroxy-2-methylbutanoyl]-3,6-dimethyl-2-benzofuran-1-one
4-(chloromethyl)-4-hydroxy-2-methoxy-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]cyclohexyl 3-(3-methyloxiran-2-yl)prop-2-enoate
C22H33ClO6 (428.19655480000006)
(3r,4as,5r)-5,8-dihydroxy-3-methyl-3,4,4a,5,6,7-hexahydro-2-benzopyran-1-one
(1r,8e,14s,15r)-1,4,8,14,15-pentamethylbicyclo[9.3.1]pentadeca-4,8,11-triene
(1'r,2s,3's,4's,5r,7'r,10'r)-3',4'-dihydroxy-10'-(hydroxymethyl)-4,4,5,14'-tetramethyl-11',12'-dithia-8',14'-diazaspiro[oxolane-2,5'-tetracyclo[8.2.2.0¹,⁸.0³,⁷]tetradecane]-3,9',13'-trione
(5s)-5-(but-3-en-1-yl)-3-(1-hydroxypropyl)-5h-furan-2-one
2-bromo-3-chloro-5-(hydroxymethyl)cyclohexa-2,5-diene-1,4-dione
C7H4BrClO3 (249.90323239999998)
4-(5-oxooxolan-2-yl)butan-2-yl 4,7-dihydroxyoct-2-enoate
(1as,2r,6r,7r,7ar,7br)-1a-(3-hydroxyprop-1-en-2-yl)-7,7a-dimethyl-2h,6h,7h,7bh-naphtho[1,2-b]oxirene-2,6-diol
1-[4-(acetyloxy)-5-methyl-3-methylidene-6-phenylhexyl]-6-[(4,6-dimethyloct-2-enoyl)oxy]-4-hydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(3z,8r,11z,13s,16r)-13-hydroxy-8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,5,10-trione
2-[(1as,2r,6r,7r,7ar,7br)-2,6-dihydroxy-7,7a-dimethyl-2h,6h,7h,7bh-naphtho[1,2-b]oxiren-1a-yl]prop-2-en-1-yl acetate
1-isothiocyanato-6-[(s)-methanesulfinyl]hexane
C8H15NOS2 (205.05950199999998)
(1r,4s,5r,7s,10z,14r,15r)-7,11,14,15-tetramethyl-3,6-dioxatetracyclo[12.4.0.0⁴,¹⁸.0⁵,⁷]octadeca-10,17-diene-4,17-diol
(3s,5r,8r,10s,13s,14r,17s)-17-hydroxy-5,10,13,14,17-pentamethyl-4,9-dioxatetracyclo[11.3.1.0³,⁵.0⁸,¹⁰]heptadec-1(16)-en-2-one
(5r,6s,7s,10as,13s,13as,14s,16ar)-5,6,16-trihydroxy-7,9,12,13-tetramethyl-14-(2-methylpropyl)-5h,6h,7h,8h,10ah,13h,13ah,14h-oxacyclododeca[3,2-d]isoindol-2-one
C25H37NO5 (431.26715920000004)
5,10-dihydroxy-6,12,17,17,21,27-hexamethyl-7,22,24,28-tetraoxahexacyclo[21.4.3.0¹,²³.0³,²¹.0⁶,¹⁵.0⁸,¹³]triaconta-8,10,12,18,26-pentaene-25,29-dione
4,6,7-trihydroxy-1-[2-(2-hydroxy-1,3-dimethyl-3,4-dihydro-2h-naphthalen-1-yl)ethyl]-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
16-benzyl-5,13,18-trihydroxy-9,14,15-trimethyl-3h,4h,5h,6h,7h,8h,9h,10h,12ah,13h,15ah,16h-oxacyclotetradeca[2,3-d]isoindol-2-one
(4r,5s)-5-acetyl-3,5-dimethoxy-2-methyl-4-[(2r)-2-methylbutanoyl]cyclopent-2-en-1-one
(2s,5r)-2-[(r)-hydroxy(4-hydroxyphenyl)methyl]-5-isopropyl-3,5-dimethoxypyrazine-2,6-diol
(3s,5s,8z,12s,13r,16s)-16-hydroxy-5,9,12,13,16-pentamethyl-4-oxatricyclo[10.3.1.0³,⁵]hexadeca-1(15),8-dien-2-one
5,8-dihydroxy-3-methyl-3,4,4a,5,6,7-hexahydro-2-benzopyran-1-one
(2s,3s)-3-methyl-2-(methylamino)-n-[(2s,5s,8s,11s,14s,17s,20s,23s,26r,27s)-6,12,18-trihydroxy-14-[(1r)-1-hydroxyethyl]-2,8,17-triisopropyl-10,16,20,22,26-pentamethyl-5,11,23-tris(2-methylpropyl)-3,9,15,21,24,28-hexaoxo-1,4,25-trioxa-7,10,13,16,19,22-hexaazacyclooctacosa-6,12,18-trien-27-yl]pentanimidic acid
C54H96N8O14 (1080.7045635999998)
8,16-dimethyl-2,10,13-trioxo-1,9-dioxacyclohexadeca-3,11-dien-5-yl acetate
4-hydroxy-6-[4,8,12,16-tetrahydroxy-11,13-dimethyl-15-(2,4,6-trimethyloctylidene)hexadeca-1,5,9,13-tetraen-1-yl]oxan-2-one
methyl (5s)-5,7-dihydroxy-3-methyl-4,6-dioxooxepino[2,3-b]chromene-5-carboxylate
1-{3-methoxy-2,6-dimethyl-7ah-furo[2,3-b]pyran-4-yl}ethanone
4-methoxy-3-methyl-6-(4-methyl-5-oxohex-2-en-2-yl)pyran-2-one
5,7-dihydroxy-8-methyl-13,16-dioxa-4-azatetracyclo[15.2.2.1³,⁶.0¹²,¹⁴]docosa-1(19),4,6,17,20-pentaen-22-one
C20H23NO5 (357.15761480000003)
(3s,4s)-3,8-dihydroxy-6-methoxy-3,4,5-trimethyl-4h-2-benzopyran-1-one
(4as,7r,10as)-7-ethenyl-1,1,4a,7-tetramethyl-3,4,5,6,8,9,10,10a-octahydro-2h-phenanthrene
5-{2-[3,6-dihydroxy-1-(3-hydroxyprop-2-enoyl)-1,3,6,8-tetramethyl-4-oxo-hexahydronaphthalen-2-yl]butoxy}-3-methyl-5-oxopent-2-enoic acid
8-hydroxy-10-propyl-3,4,5,8,9,10-hexahydrooxecin-2-one
10a,10'a-dimethyl 1,1',5,5',8,8'-hexahydroxy-6,6'-dimethyl-9,9'-dioxo-5h,5'h,6h,6'h,7h,7'h-[2,2'-bixanthene]-10a,10'a-dicarboxylate
(3s,3ar,6s,6ar,10r,14r,17as)-3-benzyl-1,6,14-trihydroxy-4,5,10-trimethyl-3h,3ah,6h,6ah,9h,10h,11h,12h,13h,14h-cyclotrideca[d]isoindol-17-one
C29H37NO4 (463.27224420000005)
(5s,5's,10ar,10'ar)-1,1',5,5',9,9'-hexahydroxy-3,3',10a,10'a-tetramethyl-5h,5'h-[2,2'-bixanthene]-8,8'-dione
(1s,3s,4s,5r,6r,7r)-1-[(4s,5r)-4-(acetyloxy)-5-methyl-3-methylidene-6-phenylhexyl]-4,7-dihydroxy-6-{[(2e)-4-methyloct-2-enoyl]oxy}-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
(9r,12as,13s,15s,15as,16s,18as)-16-benzyl-13,18-dihydroxy-9,15-dimethyl-14-methylidene-3h,4h,6h,7h,8h,9h,10h,12ah,13h,15h,15ah,16h-oxacyclotetradeca[2,3-d]isoindole-2,5-dione
C29H37NO5 (479.26715920000004)
(3z)-3-{[2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-1-methyl-5-(sec-butyl)pyrrolidine-2,4-dione
C26H39NO4 (429.28789340000003)
(3s,6s)-6-[(r)-hydroxy(4-hydroxyphenyl)methyl]-3-isopropyl-3,5,6-trimethoxypyrazin-2-ol
1-(3,5-dimethyl-6-phenylhex-3-en-1-yl)-4,6-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid
C23H28O10 (464.16823880000004)
(3s,6s)-3-(hydroxymethyl)-6-({4-[(3-methylbut-2-en-1-yl)oxy]phenyl}methyl)-3,6-dihydropyrazine-2,5-diol
3-benzyl-1,6-dihydroxy-3,10a-bis(methylsulfanyl)-5ah,6h,10h-pyrazino[1,2-a]indol-4-one
C20H22N2O3S2 (402.10717819999996)
(5z,8s,9s)-8,9,16-trihydroxy-14-methoxy-3-methyl-4,8,9,10,11,12-hexahydro-3h-2-benzoxacyclotetradecine-1,7-dione
(1s,2s,6r,7r,10s,12r,13r)-6,13-bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.0¹,¹⁰.0²,⁷]hexadecan-13-ol
4-methoxy-1,5-dimethyl-2,6-dioxocyclohex-3-en-1-yl 2-methylbutanoate
(1'r,2s,3's,4's,5r,7'r,10'r)-3'-hydroxy-10'-(hydroxymethyl)-4,4,5,16'-tetramethyl-3,9',15'-trioxo-11',12',13',14'-tetrathia-8',16'-diazaspiro[oxolane-2,5'-tetracyclo[8.4.2.0¹,⁸.0³,⁷]hexadecan]-4'-yl acetate
8-hydroxy-1-oxo-3,4-dihydro-2-benzopyran-3-carboxylic acid
(2r)-2-[(1e,3e)-hexa-1,3-dien-1-yl]-4-hydroxy-2,6-dimethylfuro[3,2-c]pyridin-3-one
2-[(2-hydroxyethyl)amino]-4-methoxy-1,5-dimethyl-6-oxocyclohexa-2,4-dien-1-yl 2-methylbutanoate
(3s,3ar,4s,6as,10s,12s,15ar)-1,12-dihydroxy-10-(hydroxymethyl)-4,5,8-trimethyl-3-(2-methylpropyl)-3h,3ah,4h,6ah,9h,10h,11h,12h-cycloundeca[d]isoindol-15-one
C25H37NO4 (415.27224420000005)
(3s,4r,5r,6s)-5-methoxy-4-[(2r,3s)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl (2e)-3-[(2r,3r)-3-methyloxiran-2-yl]prop-2-enoate
(6e,8s,9s,10r)-8,9-dihydroxy-10-propyl-3,4,5,8,9,10-hexahydrooxecin-2-one
2-hydroxy-6-methoxy-3,5-dimethylcyclohexa-2,5-diene-1,4-dione
2-hydroxy-5-(4-hydroxybenzoyl)-3-(2-methylpropanoyl)-5h-imidazol-4-one
5,9,12,13-tetramethyl-2-oxo-4-oxatricyclo[10.3.1.0³,⁵]hexadec-8-ene-16-carbaldehyde
5-methoxy-4-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl 3-(3-methyloxiran-2-yl)prop-2-enoate
(6r)-5-amino-6-hydroxy-3-methoxy-2,6-dimethyl-4-[(2r)-2-methylbutanoyl]cyclohexa-2,4-dien-1-one
1-hydroxy-8-(hydroxymethyl)-3-methoxy-6-methylxanthen-9-one
3-(1h-indol-3-ylmethyl)-6-isopropyl-3,6-dihydropyrazine-2,5-diol
C16H19N3O2 (285.14771939999997)
(3r,4r,5s,7r,9s,10r,13r,16s,17s,19r,23s,30s)-22-hydroxy-5,7,11,13,14,16-hexamethyl-2-oxa-21-azaheptacyclo[23.2.2.1³,¹⁰.0⁴,⁹.0¹²,¹⁶.0¹⁹,²³.0¹⁷,³⁰]triaconta-1(27),11,14,21,25,28-hexaene-18,20-dione
5,16-dihydroxy-7-(hydroxymethyl)-9,12,13-trimethyl-14-(2-methylpropyl)-5h,6h,7h,8h,10ah,13h,13ah,14h-oxacyclododeca[2,3-d]isoindol-2-one
C25H37NO5 (431.26715920000004)