Artemisinin (BioDeep_00000002616)

 

Secondary id: BioDeep_00000628638

natural product PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


3,12-Epoxy-12H-pyranol(4,3-j)-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR*)-(+)-

化学式: C15H22O5 (282.1467)
中文名称: 青蒿素
谱图信息: 最多检出来源 Viridiplantae(plant) 9.54%

分子结构信息

SMILES: CC1CCC2C(C(=O)OC3C24C1CCC(O3)(OO4)C)C
InChI: InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3

描述信息

D009676 - Noxae > D016877 - Oxidants > D010545 - Peroxides
D000890 - Anti-Infective Agents
(+)-artemisinin is a sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial and a plant metabolite. It is a sesquiterpene lactone and an organic peroxide.
Artemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum.
Artemisinin is a natural product found in Microliabum polymnioides, Artemisia tenuisecta, and other organisms with data available.
A sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria.
P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01B - Antimalarials > P01BE - Artemisinin and derivatives, plain
C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Origin: Plant; SubCategory_DNP: Sesquiterpenoids
CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 9
INTERNAL_ID 9; CONFIDENCE Reference Standard (Level 1)
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.152
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.156
[Raw Data] CB176_Artemisinin_pos_30eV_isCID-10eV_rep000004.txt
[Raw Data] CB176_Artemisinin_pos_20eV_isCID-10eV_rep000004.txt
[Raw Data] CB176_Artemisinin_pos_10eV_isCID-10eV_rep000004.txt
[Raw Data] CB176_Artemisinin_pos_40eV_isCID-10eV_rep000004.txt
[Raw Data] CB176_Artemisinin_pos_50eV_isCID-10eV_rep000004.txt
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].

同义名列表

77 个代谢物同义名

Qing Hau Sau; Artemisinin; 3,12-Epoxy-12H-pyranol(4,3-j)-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR*)-(+)-; (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-one; (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1, 2-benzodioxepin-10(3H)-one; (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one; (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one; (1R,4S,5R,8S,9R,12S,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one; (3R,5AS,6R,8AS,9R,12S,12AR)-3,6,9-TRIMETHYLOCTAHYDRO-3,12-EPOXYPYRANO(4,3-J )-1,2-BENZODIOXEPIN-10(3H)-ONE; (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one; (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-Trimethyloctahydro-3,12-epoxypyrano(4,3-j)(1,2)benzodioxepin-10(3H)-one; (3R,5AS,6R,8AS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one; 1,5,9-trimethyl-(1R,4S,5R,9R,12S,13R)-11,14,15,16-tetraoxatetracyclo(10.3.1.04,13.08,13)hexadecan-10-one; 1,5,9-trimethyl-(1R,4S,5R,9R,12S,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-one; Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one; 2AB44F63-5D0F-424A-AA3F-24062F9C1CED; ARTEMISININUM [WHO-IP LATIN]; BLUAFEHZUWYNDE-NNWCWBAJSA-N; Qinghaosu,Artemisinine; Qing Hau Sau [Chinese]; Artemisinina [Spanish]; Artemisinine [French]; Artemisininum [Latin]; Artemisininum (Latin); ARTEMISININ [WHO-IP]; ARTEMISININ [USP-RS]; ARTEMISININ [WHO-DD]; ARTEMISININ (USP-RS); ARTEMISININ [MART.]; Qinghaosu [Chinese]; ARTEMISININ (MART.); ARTEMISININ [INCI]; Artemisinin [INN]; Prestwick1_000498; Prestwick2_000498; Prestwick0_000498; Prestwick3_000498; Spectrum5_001098; Spectrum3_001549; Spectrum2_001512; Spectrum4_000721; ARTEMISININ [MI]; (+)-Artemisinin; UNII-9RMU91N5K2; Tox21_111750_1; (+)-Arteannuin; quing hau sau; DivK1c_000656; artemisininum; BPBio1_000435; huanghuahaosu; KBio1_000656; artemisinine; KBio2_004399; KBio2_006967; Artemisinina; KBio3_002498; KBio2_001831; Tox21_111750; IDI1_000656; qing hao su; Qing Hau SU; 9RMU91N5K2; artemsinin; quinghaosu; Artemisine; Arteannuin; qinghaosu; Qinghosu; P01BE01; Artesin; QHS; (3R)-3alpha,6beta,9-Trimethyl-3a,4,5,6,6abeta,7,8,9,10aalpha,10b-decahydro-9beta,10bbeta-epidioxypyrano[4,3,2-jk][2]benzoxepin-2(3H)-one; 3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one; NSC 369397; Qing Hau Sau



数据库引用编号

104 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

  • artemisinin biosynthesis: (+)-amorpha-4,11-diene + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ H2O + an oxidized [NADPH-hemoprotein reductase] + artemisinic alcohol

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(1)

33 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 14 AKT1, ANXA5, CTNNB1, CYP3A4, DHFR, DHPS, EGFR, G6PD, MSMP, MTOR, MYC, NFE2L2, PIK3CA, TP53
Peripheral membrane protein 3 ANXA5, G6PD, MTOR
Endosome membrane 2 EGFR, TF
Endoplasmic reticulum membrane 4 CYP3A4, EGFR, HMGCR, MTOR
Nucleus 7 AKT1, CTNNB1, EGFR, MTOR, MYC, NFE2L2, TP53
cytosol 11 AKT1, ANXA5, CTNNB1, DHFR, DHPS, G6PD, GSR, MTOR, NFE2L2, PIK3CA, TP53
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 3 CTNNB1, NFE2L2, TP53
nucleoplasm 7 AKT1, ATP2B1, CTNNB1, MTOR, MYC, NFE2L2, TP53
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 4 AKT1, ATP2B1, CTNNB1, EGFR
Cytoplasmic side 1 MTOR
lamellipodium 3 AKT1, CTNNB1, PIK3CA
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 2 ATP2B1, HMGCR
Golgi apparatus membrane 1 MTOR
Synapse 2 ATP2B1, CTNNB1
cell cortex 2 AKT1, CTNNB1
cell junction 2 CTNNB1, EGFR
cell surface 2 EGFR, TF
glutamatergic synapse 4 AKT1, ATP2B1, CTNNB1, EGFR
Golgi apparatus 1 NFE2L2
Golgi membrane 2 EGFR, MTOR
lysosomal membrane 1 MTOR
postsynapse 1 AKT1
presynaptic membrane 2 ATP2B1, CTNNB1
sarcolemma 1 ANXA5
Cytoplasm, cytosol 2 G6PD, NFE2L2
Lysosome 1 MTOR
endosome 1 EGFR
plasma membrane 8 AKT1, ATP2B1, CTNNB1, EGFR, IFNLR1, NFE2L2, PIK3CA, TF
synaptic vesicle membrane 1 ATP2B1
Membrane 12 AKT1, ANXA5, ATP2B1, CTNNB1, CYP3A4, EGFR, G6PD, HMGCR, IFNLR1, MTOR, MYC, TP53
apical plasma membrane 2 EGFR, TF
basolateral plasma membrane 3 ATP2B1, CTNNB1, EGFR
extracellular exosome 6 ANXA5, ATP2B1, CTNNB1, G6PD, GSR, TF
Lysosome membrane 1 MTOR
endoplasmic reticulum 2 HMGCR, TP53
extracellular space 4 EGFR, IL4, MSMP, TF
perinuclear region of cytoplasm 4 CTNNB1, EGFR, PIK3CA, TF
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
intercalated disc 1 PIK3CA
mitochondrion 3 DHFR, GSR, TP53
protein-containing complex 5 AKT1, CTNNB1, EGFR, MYC, TP53
intracellular membrane-bounded organelle 3 ATP2B1, CYP3A4, G6PD
Microsome membrane 2 CYP3A4, MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 2 EGFR, IFNLR1
Secreted 3 IL4, MSMP, TF
extracellular region 3 ANXA5, IL4, TF
cytoplasmic side of plasma membrane 1 G6PD
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
basal part of cell 1 TF
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 GSR, TP53
transcription regulator complex 2 CTNNB1, TP53
centriolar satellite 1 G6PD
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 EGFR
external side of plasma membrane 2 ANXA5, GSR
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
cytoplasmic vesicle 1 TF
microtubule cytoskeleton 1 AKT1
nucleolus 2 MYC, TP53
Wnt signalosome 1 CTNNB1
Early endosome 1 TF
apical part of cell 1 CTNNB1
cell-cell junction 2 AKT1, CTNNB1
clathrin-coated pit 1 TF
recycling endosome 1 TF
vesicle 2 AKT1, TF
postsynaptic membrane 1 CTNNB1
Membrane raft 1 EGFR
Cytoplasm, cytoskeleton 2 CTNNB1, TP53
focal adhesion 3 ANXA5, CTNNB1, EGFR
spindle 1 AKT1
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
intracellular vesicle 1 EGFR
peroxisomal membrane 1 HMGCR
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 ANXA5
fascia adherens 1 CTNNB1
lateral plasma membrane 2 ATP2B1, CTNNB1
Late endosome 1 TF
receptor complex 1 EGFR
Zymogen granule membrane 1 ANXA5
ciliary basal body 1 AKT1
chromatin 3 MYC, NFE2L2, TP53
mediator complex 1 NFE2L2
cell projection 1 ATP2B1
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
Nucleus, nucleolus 1 MYC
spindle pole 1 CTNNB1
blood microparticle 1 TF
postsynaptic density, intracellular component 1 CTNNB1
Basolateral cell membrane 1 ATP2B1
microvillus membrane 1 CTNNB1
site of double-strand break 1 TP53
nuclear envelope 2 MTOR, MYC
Endomembrane system 2 CTNNB1, MTOR
Nucleus, nucleoplasm 1 MYC
euchromatin 1 CTNNB1
Presynaptic cell membrane 1 ATP2B1
germ cell nucleus 1 TP53
replication fork 1 TP53
Peroxisome membrane 1 HMGCR
basal plasma membrane 2 EGFR, TF
synaptic membrane 1 EGFR
secretory granule lumen 1 TF
HFE-transferrin receptor complex 1 TF
endoplasmic reticulum lumen 1 TF
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
endocytic vesicle 1 TF
RNA polymerase II transcription repressor complex 1 MYC
beta-catenin-TCF complex 1 CTNNB1
immunological synapse 1 ATP2B1
presynaptic active zone cytoplasmic component 1 CTNNB1
vesicle membrane 1 ANXA5
clathrin-coated endocytic vesicle membrane 2 EGFR, TF
[Isoform 1]: Nucleus 1 TP53
protein-DNA complex 2 CTNNB1, NFE2L2
Rough endoplasmic reticulum 1 MYC
Cytoplasmic vesicle, phagosome 1 MTOR
catenin complex 1 CTNNB1
vesicle coat 1 TF
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
Myc-Max complex 1 MYC
endothelial microparticle 1 ANXA5
photoreceptor ribbon synapse 1 ATP2B1
beta-catenin-TCF7L2 complex 1 CTNNB1
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
dense body 1 TF
interleukin-28 receptor complex 1 IFNLR1
nucleoplasmic reticulum 1 MYC


文献列表

  • Annabelle Walz, Ursula Lehmann, Urs Duthaler, Pascal Mäser, Sergio Wittlin. In vivo antimalarial efficacy of Artemisia afra powder suspensions. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155644. doi: 10.1016/j.phymed.2024.155644. [PMID: 38761524]
  • Wenlu Sang, Cunhao Du, Lixiao Ni, Shiyin Li, Amar Ali Adam Hamad, Chu Xu, Chenxi Shao. Physiological and molecular mechanisms of the inhibitory effects of artemisinin on Microcystis aeruginosa and Chlorella pyrenoidosa. Journal of hazardous materials. 2024 May; 470(?):134241. doi: 10.1016/j.jhazmat.2024.134241. [PMID: 38608594]
  • Ishfaq Majid Hurrah, Amit Kumar, Nazia Abbas. Functional characterisation of Artemisia annua jasmonic acid carboxyl methyltransferase: a key enzyme enhancing artemisinin biosynthesis. Planta. 2024 May; 259(6):152. doi: 10.1007/s00425-024-04433-y. [PMID: 38735012]
  • Pamela Weathers, Melissa Towler, Bushra Hafeez Kiani, David Dolivo, Tanja Dominko. Differential Anti-Fibrotic and Remodeling Responses of Human Dermal Fibroblasts to Artemisia sp., Artemisinin, and Its Derivatives. Molecules (Basel, Switzerland). 2024 May; 29(9):. doi: 10.3390/molecules29092107. [PMID: 38731597]
  • Eva Kiss, Stefan Kins, Karin Gorgas, Kinga Hajnal Venczel Szakács, Joachim Kirsch, Jochen Kuhse. Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084165. [PMID: 38673751]
  • Maria Beatriz Viana Dos Santos, Alaíde Braga de Oliveira, Rosa Helena Veras Mourão. Brazilian plants with antimalarial activity: A review of the period from 2011 to 2022. Journal of ethnopharmacology. 2024 Mar; 322(?):117595. doi: 10.1016/j.jep.2023.117595. [PMID: 38122914]
  • Tian-Yu Cai, Jian-Bo Ji, Xin Wang, Jie Xing. Targeted screening of the synergistic components in Artemisia annua L. leading to enhanced antiplasmodial potency of artemisinin based on a "top down" PD-PK approach. Journal of ethnopharmacology. 2024 Mar; 322(?):117612. doi: 10.1016/j.jep.2023.117612. [PMID: 38135228]
  • Camilla Valente Pires, Debora Cassandra, Shulin Xu, Benoit Laleu, Jeremy N Burrows, John H Adams. Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum. mBio. 2024 Mar; 15(3):e0316923. doi: 10.1128/mbio.03169-23. [PMID: 38323831]
  • Wahengbam Kabita Chanu, Aditi Chatterjee, Nalini Singh, Viswanathan Arun Nagaraj, Chingakham Brajakishor Singh. Phytochemical screening, antioxidant analyses, and in vitro and in vivo antimalarial activities of herbal medicinal plant - Rotheca serrata (L.) Steane & Mabb. Journal of ethnopharmacology. 2024 Mar; 321(?):117466. doi: 10.1016/j.jep.2023.117466. [PMID: 37981115]
  • Meng-Yue Wang, Hui-Hua Wan, Li Xiang, Yu-Ting Pu, Qing-Gang Yin, Ran-Ran Gao, Yu-Hua Shi, Lan Wu. [Simultaneous determination of seven artemisinin-related compounds in Artemisia annua by UPLC-QQQ-MS/MS]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Mar; 49(5):1260-1265. doi: 10.19540/j.cnki.cjcmm.2023105.101. [PMID: 38621973]
  • Stefano Negri, Fabio Pietrolucci, Sebastiano Andreatta, Ruth Chinyere Njoku, Carolina Antunes Silva Nogueira Ramos, Massimo Crimi, Mauro Commisso, Flavia Guzzo, Linda Avesani. Bioprospecting of Artemisia genus: from artemisinin to other potentially bioactive compounds. Scientific reports. 2024 02; 14(1):4791. doi: 10.1038/s41598-024-55128-z. [PMID: 38413638]
  • Jia-He Liao, Qian He, Zi-Wei Huang, Xin-Bo Yu, Jian-Ying Yang, Yan Zhang, Wei-Jiang Song, Jing Luo, Qing-Wen Tao. Network pharmacology-based strategy to investigate the mechanisms of artemisinin in treating primary Sjögren's syndrome. BMC immunology. 2024 02; 25(1):16. doi: 10.1186/s12865-024-00605-3. [PMID: 38347480]
  • Yiyun Geng, Weichao Li, Nai-Kei Wong, Fuchong Xue, Qing Li, Yang Zhang, Jingyuan Xu, Zhangshuang Deng, Yiqing Zhou. Discovery of Artemisinins as Microsomal Prostaglandins Synthase-2 Inhibitors for the Treatment of Colorectal Cancer via Chemoproteomics. Journal of medicinal chemistry. 2024 Feb; 67(3):2083-2094. doi: 10.1021/acs.jmedchem.3c01989. [PMID: 38287228]
  • Lingyun Wan, Juan Huo, Qiulan Huang, Xiaowen Ji, Lisha Song, Zhanjiang Zhang, Limei Pan, Jine Fu, Mohamed A Abd Elhamid, Salma A Soaud, Rania M Y Heakel, Jihai Gao, Shugen Wei, Ahmed H El-Sappah. Genetics and metabolic responses of Artemisia annua L to the lake of phosphorus under the sparingly soluble phosphorus fertilizer: evidence from transcriptomics analysis. Functional & integrative genomics. 2024 Feb; 24(1):26. doi: 10.1007/s10142-024-01301-6. [PMID: 38329581]
  • Xueqing Fu, Han Zheng, Yuting Wang, Hang Liu, Pin Liu, Ling Li, Jingya Zhao, Xiaofen Sun, Kexuan Tang. AaABCG20 transporter involved in cutin and wax secretion affects the initiation and development of glandular trichomes in Artemisia annua. Plant science : an international journal of experimental plant biology. 2024 Feb; 339(?):111959. doi: 10.1016/j.plantsci.2023.111959. [PMID: 38101619]
  • Youke Wang, Xiang Yuan, Min Ren, Zhiyu Wang. Ferroptosis: A New Research Direction of Artemisinin and Its Derivatives in Anti-Cancer Treatment. The American journal of Chinese medicine. 2024; 52(1):161-181. doi: 10.1142/s0192415x24500071. [PMID: 38328829]
  • Yongpeng Li, Yinkai Yang, Pengyang Li, Miaomiao Sheng, Ling Li, Xiaojing Ma, Zhiyan Du, Kexuan Tang, Xiaolong Hao, Guoyin Kai. AaABI5 transcription factor mediates light and abscisic acid signaling to promote anti-malarial drug artemisinin biosynthesis in Artemisia annua. International journal of biological macromolecules. 2023 Dec; 253(Pt 6):127345. doi: 10.1016/j.ijbiomac.2023.127345. [PMID: 37820909]
  • Jieting Chen, Wenguang Wu, Xiaoxia Ding, Danchun Zhang, Chunyan Dai, Hengyu Pan, Peiqi Shi, Chanjuan Wu, Jun Zhang, Jianmin Zhao, Baosheng Liao, Xiaohui Qiu, Zhihai Huang. Genome-wide characterization of regulator of chromosome condensation 1 (RCC1) gene family in Artemisia annua L. revealed a conservation evolutionary pattern. BMC genomics. 2023 Nov; 24(1):692. doi: 10.1186/s12864-023-09786-4. [PMID: 37980503]
  • Adi Nath, Abhijeet Sharma, Shailendra Kumar Singh, Shanthy Sundaram. Bio Prospecting of Endophytes and PGPRs in Artemisinin Production for the Socio-economic Advancement. Current microbiology. 2023 Nov; 81(1):4. doi: 10.1007/s00284-023-03516-5. [PMID: 37947887]
  • Junfeng Cao, Zhiwen Chen, Luyao Wang, Ning Yan, Jialing Lin, Lipan Hou, Yongyan Zhao, Chaochen Huang, Tingting Wen, Chenyi Li, Saeed Ur Rahman, Zehui Liu, Jun Qiao, Jianguo Zhao, Jie Wang, Yannan Shi, Wei Qin, Tong Si, Yuliang Wang, Kexuan Tang. Graphene enhances artemisinin production in traditional medicinal plant Artemisia annua via dynamic physiological progress and miRNA regulation. Plant communications. 2023 Nov; ?(?):100742. doi: 10.1016/j.xplc.2023.100742. [PMID: 37919898]
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