Guanosine (BioDeep_00000000232)

 

Secondary id: BioDeep_00000399881

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Chemicals and Drugs BioNovoGene_Lab2019


代谢物信息卡片


2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one

化学式: C10H13N5O5 (283.0917)
中文名称: 鸟苷, 鸟嘌呤核甙
谱图信息: 最多检出来源 Homo sapiens(plant) 11.12%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Guanosine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/guanosine (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000232). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc(N)[nH]c3=O)O1)O)O)O
InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)

描述信息

Guanosine (G), also known as 2-amino-inosine, belongs to the class of organic compounds known as purine nucleosides. Purine nucleosides are compounds comprising a purine base attached to a ribosyl or deoxyribosyl sugar moiety. Guanosine consists of a guanine base attached to a ribose (ribofuranose) ring via a beta-N9-glycosidic bond. Guanosine is a white, crystalline powder with no odor and mild saline taste. It is very soluble in acetic acid, and slightly soluble in water, but insoluble in ethanol, diethyl ether, benzene, and chloroform. Guanosine exists in all living species, ranging from bacteria to plants to humans. High levels of guanosine can be found in clovers, coffee plants, and the pollen of pines. It has been detected, but not quantified in, several different foods, such as leeks, garlic, chicory roots, green bell peppers, and black-eyed peas. Guanosine plays an important role in various biochemical processes including the synthesis of nucleic acids such as RNA and intracellular signal transduction (cGMP). The antiviral drug acyclovir, often used in herpes treatment, and the anti-HIV drug abacavir, are both structurally similar to guanosine. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). In humans, guanosine is involved in intracellular signalling through the adenosine receptors A1R and A2AR (PMID: 31847113). Evidence from rodent and cell models has shown a number of important neurotrophic and neuroprotective effects of guanosine. In particular, it is effective in preventing deleterious consequences of seizures, spinal cord injury, pain, mood disorders and aging-related diseases, such as ischemia, Parkinson’s and Alzheimer’s diseases (PMID: 27699087). Studies with rodent models of Parkinson’s disease have shown that guanosine decreases neuronal apoptotic cell death and increases dopaminergic neurons at substantia nigra pars compacta, accompanied by an improvement of motor symptoms in Parkinson’s disease (i.e. a reduction of bradykinesia). Guanosine promotes neurite arborization, outgrowth, proliferation and differentiation. Systemic administration of guanosine for eight weeks (8 mg/kg) has been shown to stimulate neuroprogenitors proliferation in the subventricular zone (SVZ) in a mouse model of Parkinsonism (PMID: 27699087). The effect of guanosine treatment is accompanied by an increased number of fibroblast growth factor (FGF-2)-positive cells which is an important regulator of neuroprogenitor/stem cell proliferation, survival and differentiation (PMID: 27699087). Guanosine prevents reactive oxygen species (ROS) generation and cell death in hippocampal slices subjected to the oxygen/glucose deprivation (PMID: 31847113).
Guanosine is a purine nucleoside in which guanine is attached to ribofuranose via a beta-N(9)-glycosidic bond. It has a role as a fundamental metabolite. It is a purines D-ribonucleoside and a member of guanosines. It is functionally related to a guanine.
Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate) which are factors in signal transduction pathways.
Guanosine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Guanosine is a natural product found in Ulva australis, Allium chinense, and other organisms with data available.
Guanosine is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism.
Guanosine is a metabolite found in or produced by Saccharomyces cerevisiae.
A purine nucleoside that has guanine linked by its N9 nitrogen to the C1 carbon of ribose. It is a component of ribonucleic acid and its nucleotides play important roles in metabolism. (From Dorland, 28th ed)
Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a beta-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate). ; The nucleoside guanosine exert important neuroprotective and neuromodulator roles in the central nervous system, which may be related to inhibition of the glutamatergic neurotransmission activity. Guanosine is the specific extracellular guanine-based purines effector and indicate that its conversion occurs not only in the central nervous system but also peripherally. (PMID: 16325434); Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a ?-N9-glycosidic bond. Guanosine is found in many foods, some of which are elderberry, malus (crab apple), acerola, and arrowhead.
A purine nucleoside in which guanine is attached to ribofuranose via a beta-N(9)-glycosidic bond.
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
[Spectral] Guanosine (exact mass = 283.09167) and 3,4-Dihydroxy-L-phenylalanine (exact mass = 197.06881) and Glutathione disulfide (exact mass = 612.15196) and AMP (exact mass = 347.06308) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
[Spectral] Guanosine (exact mass = 283.09167) and Guanine (exact mass = 151.04941) and 3,4-Dihydroxy-L-phenylalanine (exact mass = 197.06881) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
Acquisition and generation of the data is financially supported in part by CREST/JST.
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.125
CONFIDENCE standard compound; INTERNAL_ID 317
KEIO_ID G015; [MS2] KO008966
Annotation level-2
KEIO_ID G015
Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.

同义名列表

92 个代谢物同义名

2-Amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one; Adenosine Imp. H (EP); Guanosine; Adenosine Impurity H; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxy-methyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-AMINO-9-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-6,9-DIHYDRO-1H-PURIN-6-ONE; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-purin-6-one; 9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-aminohydropurin -6-one; 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one; (2R,3R,4S,5R)-2-(2-amino-6-hydroxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3H-purin-6-one; 2-Amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one (Guanosine); 6H-Purin-6-one, 2-amino-1,9-dihydro-9-.beta.-D-ribofuranosyl-; 2-Amino-1,9-dihydro-9-beta-delta-ribofuranosyl-6H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl-; 2-AMINO-9-.BETA.-D-RIBOFURANOSYL-1,9-DIHYDRO-6H-PURIN-6-ONE; 2-Amino-1,9-dihydro-9.beta.-d-ribofuranosyl-6H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl; 2-Amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one; 2-amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one; 2(3H)-Imino-9-.beta.-D-ribofuranosyl-9H-purin-6(1H)-one; 2-Amino-9-b-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one; 2-Amino-9-β-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-1,9-dihydro-9-b-D-ribofuranosyl-6H-purin-6-one; 2-Amino-9-.beta.-D-ribofuranosyl-9-H-purine-6(1H)-one; 2(3H)-Imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one; 2-AMINO-9-.BETA.-D-RIBOFURANOSYL-9H-PURINE-6(1H)-ONE; 2(3H)-Imino-9-β-D-ribofuranosyl-9H-purin-6(1H)-one; 2(3H)-Imino-9-b-D-ribofuranosyl-9H-purin-6(1H)-one; 2-Amino-9-beta-D-ribofuranosyl-9H-purine-6(1H)-one; Guanosine, suitable for cell culture, BioReagent; Guanosine, Vetec(TM) reagent grade, >=98\\%; Guanine, 9-beta-D-ribofuranosyl- (VAN); Ribofuranoside, guanine-9, .beta.-D-; beta-delta-Ribofuranoside guanine-9; Ribofuranoside, guanine-9, beta-D-; 9-beta-delta-ribofuranosyl-Guanine; .beta.-D-Ribofuranoside, guanine-9; ADENOSINE IMPURITY H (EP IMPURITY); ADENOSINE IMPURITY H [EP IMPURITY]; Guanine-9-.beta.-D-ribofuranoside; Guanine, 9.beta.-d-ribofuranosyl-; beta-D-Ribofuranoside, guanine-9; Guanine, 9-beta-D-ribofuranosyl-; Guanine-9-beta-D-ribofuranoside; 9-.beta.-D-ribofuranosylguanine; 9-(beta-D-Ribofuranosyl)guanine; GUANINE-9:BETA-D-RIBOFURANOSIDE; 9-(ss--D-Ribofuranosyl)guanine; Guanine-9-ss--D-ribofuranoside; 9-beta-D-ribofuranosyl guanine; 9-beta-D-ribofuranosyl-guanine; 9-beta-D-Ribofuranosylguanine; Guanine-9-b-D-ribofuranoside; Guanine-9-β-D-ribofuranoside; b-D-Ribofuranoside guanine-9; 9-b-D-ribofuranosyl-Guanine; 9-Β-D-ribofuranosyl-guanine; 9-B-D-RIBOFURANOSYLGUANINE; Guanosine, >=97.0\\% (HPLC); GUANOSINE [USP IMPURITY]; GUANOSINE (USP IMPURITY); Inosine, 2-amino- (VAN); GUANOSINE [WHO-DD]; GUANOSINE (MART.); Guanosine, >=98\\%; Inosine, 2-amino-; GUANOSINE [MART.]; GUANOSINE [INCI]; Inosine, 2-amino; guanine riboside; 2-amino-Inosine; Ribonucleoside; GUANOSINE [MI]; [3H]-guanosine; Vernine (VAN); 3h-guanosine; DL-Guanosine; USAF CB-11; Guanosine; AI3-52065; Guanozin; Guanosin; vernine; 2fqx; 1odj; Guo; GR; G; Guanosine; Guanosine; Guanosine



数据库引用编号

70 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(14)

PlantCyc(5)

代谢反应

961 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(148)

WikiPathways(3)

Plant Reactome(0)

INOH(2)

PlantCyc(758)

COVID-19 Disease Map(2)

PathBank(48)

PharmGKB(0)

43 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ADA, AKT1, BDNF, CASP3, MAPK14, MTOR, PNP, PRKX, RELA, TLR7, TLR9
Peripheral membrane protein 2 ADA, MTOR
Endosome membrane 2 TLR7, TLR9
Endoplasmic reticulum membrane 4 CD4, MTOR, TLR7, TLR9
Nucleus 8 ADK, AKT1, CASP3, MAPK14, MTOR, PRKX, RELA, TRIM33
cytosol 10 ADA, ADK, AKT1, CASP3, GDA, MAPK14, MTOR, NT5E, PNP, RELA
dendrite 2 BDNF, MTOR
phagocytic vesicle 2 MTOR, TLR9
nucleoplasm 9 ADK, AKT1, CASP3, MAPK14, MTOR, NT5E, PRKX, RELA, TRIM33
Cell membrane 5 ADA, AKT1, CD4, NT5E, TNF
Cytoplasmic side 1 MTOR
lamellipodium 1 AKT1
Early endosome membrane 1 TLR9
Multi-pass membrane protein 1 GDA
Golgi apparatus membrane 2 MTOR, TLR9
cell cortex 1 AKT1
cell junction 1 ADA
cell surface 3 ADA, NT5E, TNF
glutamatergic synapse 4 AKT1, CASP3, MAPK14, RELA
Golgi membrane 4 INS, MTOR, TLR7, TLR9
lysosomal membrane 1 MTOR
mitochondrial inner membrane 1 GDA
neuronal cell body 2 CASP3, TNF
postsynapse 1 AKT1
synaptic vesicle 1 BDNF
Lysosome 4 ADA, MTOR, TLR7, TLR9
endosome 2 TLR7, TLR9
plasma membrane 9 ADA, ADK, AKT1, CD4, IFNLR1, NT5E, TLR7, TLR9, TNF
Membrane 8 ADA, AKT1, BDNF, IFNLR1, MTOR, NT5E, TLR7, TLR9
apical plasma membrane 1 TLR9
axon 1 BDNF
basolateral plasma membrane 1 TLR9
extracellular exosome 2 NT5E, PNP
Lysosome membrane 1 MTOR
endoplasmic reticulum 2 TLR7, TLR9
extracellular space 5 BDNF, IL6, INS, PNP, TNF
perinuclear region of cytoplasm 1 BDNF
mitochondrion 2 GDA, MAPK14
protein-containing complex 1 AKT1
Microsome membrane 1 MTOR
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 4 CD4, IFNLR1, TLR7, TLR9
Secreted 4 BDNF, IL6, INS, PNP
extracellular region 7 BDNF, IL6, INS, MAPK14, PNP, TLR9, TNF
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 1 MTOR
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 1 ADA
transcription regulator complex 1 RELA
external side of plasma membrane 4 ADA, CD4, NT5E, TNF
microtubule cytoskeleton 1 AKT1
Early endosome 1 CD4
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Mitochondrion inner membrane 1 GDA
Membrane raft 2 CD4, TNF
spindle 1 AKT1
Nucleus, PML body 1 MTOR
PML body 1 MTOR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
nuclear speck 1 MAPK14
receptor complex 1 TLR7
ciliary basal body 1 AKT1
chromatin 2 RELA, TRIM33
phagocytic cup 1 TNF
spindle pole 1 MAPK14
Lipid-anchor, GPI-anchor 1 NT5E
nuclear envelope 1 MTOR
Endomembrane system 2 MTOR, TLR7
endosome lumen 1 INS
side of membrane 1 NT5E
ficolin-1-rich granule lumen 2 MAPK14, PNP
secretory granule lumen 3 INS, MAPK14, PNP
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 BDNF, CD4, IL6, INS
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
[Isoform 2]: Cytoplasm 1 ADK
clathrin-coated endocytic vesicle membrane 1 CD4
[Isoform 1]: Nucleus 1 ADK
endolysosome membrane 2 TLR7, TLR9
death-inducing signaling complex 1 CASP3
early phagosome 2 TLR7, TLR9
Cytoplasmic vesicle, phagosome 3 MTOR, TLR7, TLR9
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
interleukin-6 receptor complex 1 IL6
endolysosome 1 TLR9
NF-kappaB p50/p65 complex 1 RELA
NF-kappaB complex 1 RELA
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Yiping Li, Xiaolong Wang. The role of DNA and RNA guanosine oxidation in cardiovascular diseases. Pharmacological research. 2024 Jun; 204(?):107187. doi: 10.1016/j.phrs.2024.107187. [PMID: 38657843]
  • Yaning Wu, Hongwei Zhang, Jianguang Zhu, Zhenling Zhang, Songbo Ma, Yongqi Zhao, Yiming Wang, Jun Yuan, Xing Guo, Yajing Li, Shuai Zhang. The Effect of Fermentation on the Chemical Constituents of Gastrodia Tuber Hallimasch Powder (GTHP) Estimated by UHPLC-Q-Orbitrap HRMS and HPLC. Molecules (Basel, Switzerland). 2024 Apr; 29(7):. doi: 10.3390/molecules29071663. [PMID: 38611942]
  • Zihan Li, Chengshan Zhu, Cong Yin, Heyu Li, Yimei Liu, Juan Li. Multi-omics reveals the testosterone promotion effect mechanism of Cordyceps Sobolifera on leydig cells. Journal of ethnopharmacology. 2024 Feb; ?(?):117817. doi: 10.1016/j.jep.2024.117817. [PMID: 38316217]
  • Anna Lewicka, Christina Roman, Stacey Jones, Michael Disare, Phoebe A Rice, Joseph A Piccirilli. Crystal structure of a cap-independent translation enhancer RNA. Nucleic acids research. 2023 Aug; ?(?):. doi: 10.1093/nar/gkad649. [PMID: 37548413]
  • Rozielly Aparecida Lemes Dos Santos, Silvia Regina de Lima Reis, Patrícia Cristiane Gibbert, Cristina Maria de Arruda, Diego Luiz Doneda, Yohan Alves Victor de Matos, Giordano Gubert Viola, Fabrício Rios Santos, Eliângela de Lima, Ziliani da Silva Buss, Samuel Vandresen-Filho. Guanosine treatment prevents lipopolysaccharide-induced depressive-like behavior in mice. Journal of psychiatric research. 2023 Jun; 164(?):296-303. doi: 10.1016/j.jpsychires.2023.06.022. [PMID: 37392719]
  • Maria Godoy-Gallardo, Maria Merino-Gómez, Miguel A Mateos-Timoneda, Ulrich Eckhard, F Javier Gil, Roman A Perez. Advanced Binary Guanosine and Guanosine 5'-Monophosphate Cell-Laden Hydrogels for Soft Tissue Reconstruction by 3D Bioprinting. ACS applied materials & interfaces. 2023 Jun; ?(?):. doi: 10.1021/acsami.2c23277. [PMID: 37319328]
  • Ezhar Ersöz, Mehmet Salıh Aydın, Yasemin Hacanlı, Nazım Kankılıç, İsmail Koyuncu, Muhammet Emin Güldür, Ebru Temiz, Yusuf Çakmak, Kadir Eği, Reşat Dikme, Mahmut Padak. Cardioprotective Effect of Pistacia vera L. (Green Pistachio) Hull Extract in Wistar Albino Rats with Doxorubicin-Induced Cardiac Damage. Anatolian journal of cardiology. 2023 03; 27(3):135-145. doi: 10.14744/anatoljcardiol.2022.2452. [PMID: 36856595]
  • Yi-Fang Chen, Yan Wang, Yue Wang, Ying-Li Luo, Zi-Dong Lu, Xiao-Jiao Du, Cong-Fei Xu, Jun Wang. Optimized Cationic Lipid-assisted Nanoparticle for Delivering CpG Oligodeoxynucleotides to Treat Hepatitis B Virus Infection. Pharmaceutical research. 2023 Jan; 40(1):145-156. doi: 10.1007/s11095-022-03307-w. [PMID: 36002611]
  • Wei Liu, Chunxia G Cronin, Ziming Cao, Chengliang Wang, Jianbin Ruan, Sunitha Pulikkot, Alexxus Hall, Hao Sun, Alex Groisman, Yunfeng Chen, Anthony T Vella, Liang Hu, Bruce T Liang, Zhichao Fan. Nexinhib20 Inhibits Neutrophil Adhesion and β2 Integrin Activation by Antagonizing Rac-1-Guanosine 5'-Triphosphate Interaction. Journal of immunology (Baltimore, Md. : 1950). 2022 10; 209(8):1574-1585. doi: 10.4049/jimmunol.2101112. [PMID: 36165184]
  • Mizuho Ichinose, Masuyo Kawabata, Yumi Akaiwa, Yasuka Shimajiri, Izumi Nakamura, Takayuki Tamai, Takahiro Nakamura, Yusuke Yagi, Bernard Gutmann. U-to-C RNA editing by synthetic PPR-DYW proteins in bacteria and human culture cells. Communications biology. 2022 09; 5(1):968. doi: 10.1038/s42003-022-03927-3. [PMID: 36109586]
  • Chenchen Ma, Peng Liu, Siyuan Cui, Chang Gao, Xing Tan, Zhaopeng Liu, Ruirong Xu. The Identification of APOBEC3G as a Potential Prognostic Biomarker in Acute Myeloid Leukemia and a Possible Drug Target for Crotonoside. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27185804. [PMID: 36144542]
  • Negar Shahsavari, Boyuan Wang, Yu Imai, Miho Mori, Sangkeun Son, Libang Liang, Nils Böhringer, Sylvie Manuse, Michael F Gates, Madeleine Morrissette, Rachel Corsetti, Josh L Espinoza, Chris L Dupont, Michael T Laub, Kim Lewis. A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP. mBio. 2022 06; 13(3):e0070022. doi: 10.1128/mbio.00700-22. [PMID: 35575547]
  • Zsuzsanna Ament, Amit Patki, Ninad Chaudhary, Varun M Bhave, Ana-Lucia Garcia Guarniz, Yan Gao, Robert E Gerszten, Adolfo Correa, Suzanne E Judd, Mary Cushman, D Leann Long, M Ryan Irvin, W Taylor Kimberly. Nucleosides Associated With Incident Ischemic Stroke in the REGARDS and JHS Cohorts. Neurology. 2022 05; 98(21):e2097-e2107. doi: 10.1212/wnl.0000000000200262. [PMID: 35264422]
  • Weili Yu, Lijuan Shen, Jinming Qi, Tao Hu. Conjugation with loxoribine and mannan improves the immunogenicity of Mycobacterium tuberculosis CFP10-TB10.4 fusion protein. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2022 Mar; 172(?):193-202. doi: 10.1016/j.ejpb.2022.02.011. [PMID: 35183715]
  • Valentina Roviello, Melinda Gilhen-Baker, Caterina Vicidomini, Giovanni N Roviello. The Healing Power of Clean Rivers: In Silico Evaluation of the Antipsoriatic Potential of Apiin and Hyperoside Plant Metabolites Contained in River Waters. International journal of environmental research and public health. 2022 02; 19(5):. doi: 10.3390/ijerph19052502. [PMID: 35270196]
  • Sven Dierickx, Karolien Maes, Sophie L K W Roelants, Beata Pomian, Lieven Van Meulebroek, Sofie L De Maeseneire, Lynn Vanhaecke, Wim K Soetaert. A multi-omics study to boost continuous bolaform sophorolipid production. New biotechnology. 2022 Jan; 66(?):107-115. doi: 10.1016/j.nbt.2021.11.002. [PMID: 34774786]
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