Vetol (BioDeep_00000862363)

Main id: BioDeep_00000002881

 

PANOMIX_OTCML-2023 Chemicals and Drugs


代谢物信息卡片


5-18-01-00114 (Beilstein Handbook Reference)

化学式: C6H6O3 (126.0317)
中文名称: 麦芽酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C(=O)C=CO1)O
InChI: InChI=1S/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3

描述信息

C1907 - Drug, Natural Product > C28269 - Phytochemical
Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food[1].
Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food[1].

同义名列表

71 个代谢物同义名

5-18-01-00114 (Beilstein Handbook Reference); 3-Hydroxy-2-methyl-4-pyrone solution; 4H-Pyran-4-one, 3-hydroxy-2-methyl-; 3-Hydroxy-2-methyl-4H-pyran-4-one; 3-Hydroxy-2-methyl-.gamma.-pyrone; 3-Hydroxy-2-methyl-gamma-pyrone; 3-Hydroxy-2-methyl-pyran-4-one; 3-Hydroxy-2-methyl-4-pyranone; 3-hydroxy-2-methylpyran-4-one; 3-hydroxy-2-methyl-4-pyrone; 2-Methyl-3-hydroxy-4-pyrone; 2-Methyl-3-oxy-gamma-pyrone; 2-Methyl pyromeconic acid; 2-Methylpyromeconic acid; 3-Hydroxy-2-methylpyrone; 2-Methyl-3-hydroxypyrone; SDCCGMLS-0066563.P001; WLN: T6O DVJ B1 CQ; Spectrum4_001871; Maltol (natural); Spectrum5_000462; EINECS 204-271-8; Spectrum3_001351; Spectrum2_001795; NCGC00091223-01; NCGC00091223-02; Spectrum_001419; SpecPlus_000443; W265616_ALDRICH; Maltol solution; W265624_ALDRICH; W265608_ALDRICH; H43407_ALDRICH; SPECTRUM310025; Larixinic acid; KBioGR_002365; FEMA No. 2656; KBioSS_001899; DivK1c_006539; Corps praline; BSPBio_003161; KBio2_001899; KBio2_007035; SMR000059093; SPBio_001749; KBio1_001483; ZINC00164488; NCI60_002320; KBio2_004467; Larixic acid; MLS000069412; KBio3_002381; 55849_FLUKA; BRN 0112169; AIDS-009883; AIDS009883; CCRIS 3467; AI3-18547; NSC404458; ST5330599; Palatone; 118-71-8; NSC 2829; NSC2829; Maltol; LS-602; Talmon; C11918; Vetol; Maltol; Maltol



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

31 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AKT1, ALB, CASP3, CAT, CYP2E1, MTOR, NOS2, PIK3C3, PIK3CA, PRKAA2, PTGS2, TYR
Peripheral membrane protein 4 CYP1B1, CYP2E1, MTOR, PTGS2
Endosome membrane 1 TF
Endoplasmic reticulum membrane 5 CYP1B1, CYP2E1, HMOX1, MTOR, PTGS2
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 8 AKT1, ALB, CASP3, GABPA, HMOX1, MTOR, NOS2, PRKAA2
autophagosome 1 PIK3C3
cytosol 10 AKT1, ALB, CASP3, CAT, HMOX1, MTOR, NOS2, PIK3C3, PIK3CA, PRKAA2
dendrite 2 MTOR, PRKAA2
phagocytic vesicle 1 MTOR
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 1 ALB
nucleoplasm 7 AKT1, CASP3, GABPA, HMOX1, MTOR, NOS2, PRKAA2
Cell membrane 2 AKT1, TNF
Cytoplasmic side 2 HMOX1, MTOR
lamellipodium 2 AKT1, PIK3CA
Golgi apparatus membrane 1 MTOR
Synapse 1 ACAN
cell cortex 1 AKT1
cell surface 2 TF, TNF
glutamatergic synapse 4 ACAN, AKT1, CASP3, PIK3C3
Golgi apparatus 2 ALB, PRKAA2
Golgi membrane 2 INS, MTOR
lysosomal membrane 1 MTOR
mitochondrial inner membrane 1 CYP2E1
neuronal cell body 3 CASP3, PRKAA2, TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 1 NOS2
Lysosome 2 MTOR, TYR
endosome 1 PIK3C3
plasma membrane 5 AKT1, NOS2, PIK3CA, TF, TNF
Membrane 7 AKT1, CAT, CYP1B1, HMOX1, MTOR, PIK3C3, PRKAA2
apical plasma membrane 1 TF
axon 1 PRKAA2
caveola 1 PTGS2
extracellular exosome 3 ALB, CAT, TF
Lysosome membrane 1 MTOR
endoplasmic reticulum 3 ALB, HMOX1, PTGS2
extracellular space 7 ACAN, ALB, HMOX1, IL6, INS, TF, TNF
lysosomal lumen 1 ACAN
perinuclear region of cytoplasm 5 HMOX1, NOS2, PIK3CA, TF, TYR
intercalated disc 1 PIK3CA
mitochondrion 2 CAT, CYP1B1
protein-containing complex 4 AKT1, ALB, CAT, PTGS2
intracellular membrane-bounded organelle 4 CAT, CYP1B1, CYP2E1, TYR
Microsome membrane 4 CYP1B1, CYP2E1, MTOR, PTGS2
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 TYR
Secreted 4 ALB, IL6, INS, TF
extracellular region 7 ACAN, ALB, CAT, IL6, INS, TF, TNF
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 2 HMOX1, MTOR
basal part of cell 1 TF
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 ACAN
cytoplasmic vesicle 1 TF
microtubule cytoskeleton 1 AKT1
Melanosome membrane 1 TYR
midbody 1 PIK3C3
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 1 TF
cell-cell junction 1 AKT1
clathrin-coated pit 1 TF
Golgi-associated vesicle 1 TYR
recycling endosome 2 TF, TNF
Single-pass type II membrane protein 1 TNF
vesicle 2 AKT1, TF
Cytoplasm, perinuclear region 1 NOS2
Mitochondrion inner membrane 1 CYP2E1
Membrane raft 1 TNF
focal adhesion 1 CAT
spindle 1 AKT1
GABA-ergic synapse 2 ACAN, PIK3C3
Peroxisome 3 CAT, NOS2, PIK3C3
basement membrane 1 ACAN
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, NOS2
peroxisomal membrane 1 CAT
Nucleus, PML body 1 MTOR
PML body 1 MTOR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 ACAN
axoneme 1 PIK3C3
nuclear speck 1 PRKAA2
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 2 PIK3C3, TF
neuron projection 1 PTGS2
ciliary basal body 2 AKT1, ALB
chromatin 1 GABPA
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, TF
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
endosome lumen 1 INS
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
Melanosome 1 TYR
cytoplasmic stress granule 1 PRKAA2
basal plasma membrane 1 TF
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, INS, TF
HFE-transferrin receptor complex 1 TF
Golgi lumen 2 ACAN, INS
endoplasmic reticulum lumen 5 ALB, IL6, INS, PTGS2, TF
platelet alpha granule lumen 1 ALB
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
endocytic vesicle 1 TF
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
perineuronal net 1 ACAN
presynaptic endosome 1 PIK3C3
Single-pass type IV membrane protein 1 HMOX1
clathrin-coated endocytic vesicle membrane 1 TF
death-inducing signaling complex 1 CASP3
nucleotide-activated protein kinase complex 1 PRKAA2
Cytoplasmic vesicle, phagosome 1 MTOR
vesicle coat 1 TF
postsynaptic endosome 1 PIK3C3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
Autolysosome 1 PIK3C3
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
perisynaptic extracellular matrix 1 ACAN
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
ciliary transition fiber 1 ALB
dense body 1 TF
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Wan-Lin Xiao, Na Wang, Lin-Li Yang, Yu-Mei Feng, Pan-Long Chu, Jiao-Jiao Zhang, Shuai-Shuai Liu, Wu-Bin Shao, Xiang Zhou, Li-Wei Liu, Song Yang. Exploiting Natural Maltol for Synthesis of Novel Hydroxypyridone Derivatives as Promising Anti-Virulence Agents in Bactericides Discovery. Journal of agricultural and food chemistry. 2023 May; 71(17):6603-6616. doi: 10.1021/acs.jafc.3c00465. [PMID: 37083434]
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  • Sofi Imtiyaz Ali, Venkatesalu Venugopalan. Mosquito larvicidal potential of hydroxy-2-methyl-4H-pyran-4-one (MALTOL) isolated from the methanol root extract of Senecio laetus Edgew. and its in-silico study. Natural product research. 2021 May; 35(10):1741-1745. doi: 10.1080/14786419.2019.1634712. [PMID: 31244340]
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  • Sumra Naqvi, Humera Anwer, Syed Waseem Ahmed, Asma Siddiqui, Muhammad Raza Shah, Saima Khaliq, Ayaz Ahmed, Syed Abid Ali. Synthesis and characterization of maltol capped silver nanoparticles and their potential application as an antimicrobial agent and colorimetric sensor for cysteine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2020 Mar; 229(?):118002. doi: 10.1016/j.saa.2019.118002. [PMID: 31923785]
  • Ji-Yue Sha, Yan-Dan Zhou, Jia-Yu Yang, Jing Leng, Jian-Hao Li, Jun-Nan Hu, Wei Liu, Shuang Jiang, Ying-Ping Wang, Chen Chen, Wei Li. Maltol (3-Hydroxy-2-methyl-4-pyrone) Slows d-Galactose-Induced Brain Aging Process by Damping the Nrf2/HO-1-Mediated Oxidative Stress in Mice. Journal of agricultural and food chemistry. 2019 Sep; 67(37):10342-10351. doi: 10.1021/acs.jafc.9b04614. [PMID: 31461273]
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  • Xiao-Jie Mi, Jin-Gang Hou, Zi Wang, Ye Han, Shen Ren, Jun-Nan Hu, Chen Chen, Wei Li. The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways. Scientific reports. 2018 10; 8(1):15922. doi: 10.1038/s41598-018-34156-6. [PMID: 30374107]
  • Wei Liu, Zi Wang, Jin-Gang Hou, Yan-Dan Zhou, Yu-Fang He, Shuang Jiang, Ying-Ping Wang, Shen Ren, Wei Li. The Liver Protection Effects of Maltol, a Flavoring Agent, on Carbon Tetrachloride-Induced Acute Liver Injury in Mice via Inhibiting Apoptosis and Inflammatory Response. Molecules (Basel, Switzerland). 2018 Aug; 23(9):. doi: 10.3390/molecules23092120. [PMID: 30142916]
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  • Sang-Jun Lee, Tae Wha Moon, Jaehwan Lee. Increases of 2-furanmethanol and maltol in Korean red ginseng during explosive puffing process. Journal of food science. 2010 Mar; 75(2):C147-51. doi: 10.1111/j.1750-3841.2009.01461.x. [PMID: 20492218]
  • Tamás Jakusch, Annalisa Dean, Tamás Oncsik, Attila Csaba Bényei, Valerio Di Marco, Tamás Kiss. Vanadate complexes in serum: a speciation modeling study. Dalton transactions (Cambridge, England : 2003). 2010 Jan; ?(1):212-20. doi: 10.1039/b914849c. [PMID: 20023952]
  • Tamás Jakusch, Dominik Hollender, Eva Anna Enyedy, Cristina Sánchez González, Maria Montes-Bayón, Alfredo Sanz-Medel, João Costa Pessoa, Isabel Tomaz, Tamás Kiss. Biospeciation of various antidiabetic V(IV)O compounds in serum. Dalton transactions (Cambridge, England : 2003). 2009 Apr; ?(13):2428-37. doi: 10.1039/b817748a. [PMID: 19290378]
  • K S Kang, T Tanaka, E J Cho, T Yokozawa. Evaluation of the peroxynitrite scavenging activity of heat-processed ginseng. Journal of medicinal food. 2009 Feb; 12(1):124-30. doi: 10.1089/jmf.2007.0646. [PMID: 19298205]
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  • Ki Sung Kang, Noriko Yamabe, Hyun Young Kim, Takako Yokozawa. Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies. The Journal of pharmacy and pharmacology. 2008 Apr; 60(4):445-52. doi: 10.1211/jpp.60.4.0006. [PMID: 18380916]
  • Yuzhao Zhou, Wesley R Harris, Robert A Yokel. The influence of citrate, maltolate and fluoride on the gastrointestinal absorption of aluminum at a drinking water-relevant concentration: A 26Al and 14C study. Journal of inorganic biochemistry. 2008 Apr; 102(4):798-808. doi: 10.1016/j.jinorgbio.2007.11.019. [PMID: 18207247]
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  • Geoffrey C Kite, Charlotte A Stoneham, Nigel C Veitch. Flavonol tetraglycosides and other constituents from leaves of Styphnolobium japonicum (Leguminosae) and related taxa. Phytochemistry. 2007 May; 68(10):1407-16. doi: 10.1016/j.phytochem.2007.03.004. [PMID: 17462679]
  • Eva Anna Enyedy, László Horváth, Krisztina Gajda-Schrantz, Gábor Galbács, Tamás Kiss. An in vitro study of interactions between insulin-mimetic zinc(II) complexes and selected plasma components. Journal of inorganic biochemistry. 2006 Dec; 100(12):1936-45. doi: 10.1016/j.jinorgbio.2006.08.003. [PMID: 17034863]
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