Spermine (BioDeep_00000405428)

Main id: BioDeep_00000001433

Secondary id: BioDeep_00000864367

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


4,6-Decadiene

化学式: C10H26N4 (202.2157)
中文名称: 松油精, 精胺, 精胺 四盐酸盐, 4,6-癸二烯
谱图信息: 最多检出来源 Homo sapiens(blood) 54.05%

分子结构信息

SMILES: C(CCNCCCN)CNCCCN
InChI: InChI=1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2

描述信息

A polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism.
Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.
Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.

同义名列表

7 个代谢物同义名

4,6-Decadiene; Spermine; NSC 268508; Neuridine; Spermine; 4,6-Decadiene; Spermine



数据库引用编号

59 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

173 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AOC3, ARG1, AZIN2, CA1, EIF5A, NOS2, ODC1, PAOX, SAT1
Peripheral membrane protein 2 AOC1, EIF5A
Endoplasmic reticulum membrane 1 EIF5A
Nucleus 5 ARG1, AZIN2, EIF5A, NOS2, PLCZ1
cytosol 13 AMD1, ARG1, AZIN2, CA1, EIF5A, NOS2, ODC1, PAOX, PLCZ1, PRKCQ, SAT1, SMS, SRM
dendrite 1 AZIN2
trans-Golgi network 1 AZIN2
nucleoplasm 3 ATP2B1, NOS2, PLCZ1
Cell membrane 5 AOC1, AOC3, ATP2B1, SAT1, TNF
Cytoplasmic side 1 EIF5A
Cytoplasmic granule 1 ARG1
Multi-pass membrane protein 3 ATP2B1, MCU, SAT1
Synapse 1 ATP2B1
cell surface 2 AOC3, TNF
glutamatergic synapse 1 ATP2B1
Golgi apparatus 1 AOC3
mitochondrial inner membrane 1 MCU
neuronal cell body 2 SAT1, TNF
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 2 NOS2, SAT1
plasma membrane 7 AOC1, AOC3, ATP2B1, NOS2, PRKCQ, SAT1, TNF
synaptic vesicle membrane 1 ATP2B1
Membrane 6 AOC3, ATP2B1, AZIN2, EIF5A, MCU, SAT1
axon 2 AZIN2, SAT1
basolateral plasma membrane 2 ATP2B1, SAT1
extracellular exosome 6 AOC1, ATP2B1, CA1, LYZ, SAT1, SMS
endoplasmic reticulum 1 AOC3
extracellular space 5 AOC1, ARG1, IL6, LYZ, TNF
perinuclear region of cytoplasm 3 AZIN2, NOS2, PLCZ1
bicellular tight junction 1 AOC1
mitochondrion 2 AZIN2, MCU
intracellular membrane-bounded organelle 1 ATP2B1
pronucleus 1 PLCZ1
Secreted 1 IL6
extracellular region 5 AOC1, ARG1, IL6, LYZ, TNF
Extracellular side 1 AOC1
centriolar satellite 1 PRKCQ
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 1 TNF
perikaryon 1 AZIN2
cytoplasmic vesicle 1 AZIN2
nucleolus 1 PLCZ1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 1 AOC3
recycling endosome 1 TNF
Single-pass type II membrane protein 2 AOC3, TNF
Cytoplasm, perinuclear region 2 NOS2, PLCZ1
Mitochondrion inner membrane 1 MCU
Membrane raft 1 TNF
cis-Golgi network 1 AZIN2
Peroxisome 3 AOC1, NOS2, PAOX
peroxisomal matrix 2 NOS2, PAOX
lateral plasma membrane 1 ATP2B1
cell projection 1 ATP2B1
phagocytic cup 1 TNF
Secreted, extracellular space 1 AOC1
Basolateral cell membrane 2 ATP2B1, SAT1
nuclear pore 1 EIF5A
microvillus 1 AOC3
Presynaptic cell membrane 1 ATP2B1
endoplasmic reticulum lumen 1 IL6
specific granule lumen 3 AOC1, ARG1, LYZ
tertiary granule lumen 1 LYZ
transport vesicle 1 AZIN2
azurophil granule lumen 2 ARG1, LYZ
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 AZIN2
immunological synapse 2 ATP2B1, PRKCQ
aggresome 1 PRKCQ
calcium channel complex 1 MCU
annulate lamellae 1 EIF5A
endoplasmic reticulum-Golgi intermediate compartment 1 AZIN2
external side of apical plasma membrane 1 SAT1
Golgi apparatus, cis-Golgi network 1 AZIN2
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
sperm head 1 PLCZ1
interleukin-6 receptor complex 1 IL6
photoreceptor ribbon synapse 1 ATP2B1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
uniplex complex 1 MCU
granular vesicle 1 AZIN2


文献列表

  • Yoshihiro Takahashi. ACL5 acquired strict thermospermine synthesis activity during the emergence of vascular plants. The New phytologist. 2024 Jun; 242(6):2669-2681. doi: 10.1111/nph.19733. [PMID: 38587066]
  • Bin Li, Jue Liang, Hamid R Baniasadi, Shin Kurihara, Margaret A Phillips, Anthony J Michael. Functional identification of bacterial spermine, thermospermine, norspermine, norspermidine, spermidine, and N1-aminopropylagmatine synthases. The Journal of biological chemistry. 2024 May; 300(5):107281. doi: 10.1016/j.jbc.2024.107281. [PMID: 38588807]
  • Tatiana J Carneiro, Ana L M Batista de Carvalho, Martin Vojtek, Raquel C Laginha, Maria Paula M Marques, Carmen Diniz, Ana M Gil. Pd2Spermine as an Alternative Therapeutics for Cisplatin-Resistant Triple-Negative Breast Cancer. Journal of medicinal chemistry. 2024 Apr; 67(8):6839-6853. doi: 10.1021/acs.jmedchem.4c00435. [PMID: 38590144]
  • Ludan Cao, Guo Wang, Xiuxu Ye, Fang Li, Shujun Wang, Huanling Li, Peng Wang, Jiabao Wang. Physiological, Metabolic, and Transcriptomic Analyses Reveal Mechanisms of Proliferation and Somatic Embryogenesis of Litchi (Litchi chinensis Sonn.) Embryogenic Callus Promoted by D-Arginine Treatment. International journal of molecular sciences. 2024 Apr; 25(7):. doi: 10.3390/ijms25073965. [PMID: 38612774]
  • Huafu Mai, Tian Qin, Huan Wei, Zhen Yu, Gang Pang, Zhiman Liang, Jiansheng Ni, Haishan Yang, Haiying Tang, Lisi Xiao, Huili Liu, Taibo Liu. Overexpression of OsACL5 triggers environmentally-dependent leaf rolling and reduces grain size in rice. Plant biotechnology journal. 2024 Apr; 22(4):833-847. doi: 10.1111/pbi.14227. [PMID: 37965680]
  • Jiangtao Qiao, Wenwen Cai, Kai Wang, Eric Haubruge, Jie Dong, Hesham R El-Seedi, Xiang Xu, Hongcheng Zhang. New Insights into Identification, Distribution, and Health Benefits of Polyamines and Their Derivatives. Journal of agricultural and food chemistry. 2024 Mar; 72(10):5089-5106. doi: 10.1021/acs.jafc.3c08556. [PMID: 38416110]
  • Yanxiao Yang, Ying Wei, Meizhen Yin, Enliang Liu, Xiangge Du, Jie Shen, Min Dong, Shuo Yan. Efficient Polyamine-Based Nanodelivery System for Proline: Enhanced Uptake Improves the Drought Tolerance of Tobacco. Journal of agricultural and food chemistry. 2024 Jan; 72(3):1550-1560. doi: 10.1021/acs.jafc.3c05636. [PMID: 38207102]
  • Bizhen Cheng, Muhammad Jawad Hassan, Dandan Peng, Ting Huang, Yan Peng, Zhou Li. Spermidine or spermine pretreatment regulates organic metabolites and ions homeostasis in favor of white clover seed germination against salt toxicity. Plant physiology and biochemistry : PPB. 2024 Jan; 207(?):108379. doi: 10.1016/j.plaphy.2024.108379. [PMID: 38266560]
  • Xiaoran Zhao, Qi Xu, Qian Wang, Xingxing Liang, Jing Wang, Hongwei Jin, Yizhi Man, Dongyang Guo, Feng Gao, Xinjing Tang. Induced Self-Assembly of Vitamin E-Spermine/siRNA Nanocomplexes via Spermine/Helix Groove-Specific Interaction for Efficient siRNA Delivery and Antitumor Therapy. Advanced healthcare materials. 2024 Jan; ?(?):e2303186. doi: 10.1002/adhm.202303186. [PMID: 38234201]
  • Takuya Furumoto, Shohei Yamaoka, Takayuki Kohchi, Hiroyasu Motose, Taku Takahashi. Thermospermine is an evolutionarily ancestral phytohormone required for organ development and stress responses in Marchantia polymorpha. Plant & cell physiology. 2024 Jan; ?(?):. doi: 10.1093/pcp/pcae002. [PMID: 38179828]
  • Wenlong Nie, Yun Liu, Jinshuai Lan, Ting Li, Yitian He, Zhe Li, Tong Zhang, Yue Ding. Self-Assembled Nanoparticles from Xie-Bai-San Decoction: Isolation, Characterization and Enhancing Oral Bioavailability. International journal of nanomedicine. 2024; 19(?):3405-3421. doi: 10.2147/ijn.s449268. [PMID: 38617795]
  • P R Manhone, J C Lopes, R S Alexandre, P A M Lima, S O Lopes, L H G Mengarda, T Mello. Plant growth regulators and mobilization of reserves in imbibition phases of yellow passion fruit. Brazilian journal of biology = Revista brasleira de biologia. 2024; 84(?):e273999. doi: 10.1590/1519-6984.273999. [PMID: 38451628]
  • Friederike Adams, Christoph M Zimmermann, Domizia Baldassi, Thomas M Pehl, Philipp Weingarten, Iris Kachel, Moritz Kränzlein, David C Jürgens, Peter Braubach, Ioannis Alexopoulos, Malgorzata Wygrecka, Olivia M Merkel. Pulmonary siRNA Delivery with Sophisticated Amphiphilic Poly(Spermine Acrylamides) for the Treatment of Lung Fibrosis. Small (Weinheim an der Bergstrasse, Germany). 2023 Dec; ?(?):e2308775. doi: 10.1002/smll.202308775. [PMID: 38126895]
  • Daniela S C Bispo, Marlene Correia, Tatiana J Carneiro, Ana S Martins, Aliana A N Reis, Ana L M Batista de Carvalho, Maria P M Marques, Ana M Gil. Impact of Conventional and Potential New Metal-Based Drugs on Lipid Metabolism in Osteosarcoma MG-63 Cells. International journal of molecular sciences. 2023 Dec; 24(24):. doi: 10.3390/ijms242417556. [PMID: 38139388]
  • Edward Calabrese, A Wallace Hayes, Peter Pressman, Rachna Kapoor, Gaurav Dhawan, Vittorio Calabrese, Evgenios Agathokleous. Polyamines and hormesis: Making sense of a dose response dichotomy. Chemico-biological interactions. 2023 Dec; 386(?):110748. doi: 10.1016/j.cbi.2023.110748. [PMID: 37816449]
  • Wenjuan Wang, Shangli Shi, Wenjuan Kang, Long He. Enriched endogenous free Spd and Spm in alfalfa (Medicago sativa L.) under drought stress enhance drought tolerance by inhibiting H2O2 production to increase antioxidant enzyme activity. Journal of plant physiology. 2023 Dec; 291(?):154139. doi: 10.1016/j.jplph.2023.154139. [PMID: 37988872]
  • Shima Shahtousi, Ladan Talaee. The effect of spermine on Tetranychus urticae-Cucumis sativus interaction. BMC plant biology. 2023 Nov; 23(1):575. doi: 10.1186/s12870-023-04573-5. [PMID: 37978429]
  • Bing Gao, Xiangyue Liu, Zhenghong Feng, Jianhui Wu, Jinghong Wang. Potentilla sericea stress-responsive spermine synthase PsSPMS enhances cadmium tolerance in Arabidopsis thaliana. Chemosphere. 2023 Sep; ?(?):140194. doi: 10.1016/j.chemosphere.2023.140194. [PMID: 37717914]
  • Andleeb Zehra, Harshal V Dhondge, Vitthal T Barvkar, Sanjay K Singh, Altafhusain B Nadaf. Evidence of polyamines mediated 2-acetyl-1-pyrroline biosynthesis in aromatic rice rhizospheric fungal species Aspergillus niger. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2023 Sep; ?(?):. doi: 10.1007/s42770-023-01124-w. [PMID: 37702923]
  • Wanhui Wei, Yuanyuan Lu, Qian Hu, Jinwen Yin, Youwei Wang, Heng Zhang, Qiu Zhao, Lan Liu. Synergistic antitumor efficacy of gemcitabine and cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via Sp1-SAT1-polyamine metabolism pathway. Cellular oncology (Dordrecht). 2023 Sep; ?(?):. doi: 10.1007/s13402-023-00870-1. [PMID: 37684512]
  • Yonghong He, Nannan Su, Qingzhao Zhao, Jiaer Meng, Zhaojin Chen, Hui Han. Polyamine-producing bacteria inhibit the absorption of Cd by spinach and alter the bacterial community composition of rhizosphere soil. Ecotoxicology and environmental safety. 2023 Sep; 264(?):115442. doi: 10.1016/j.ecoenv.2023.115442. [PMID: 37672938]
  • Chi Zhang, Kostadin E Atanasov, Ester Murillo, Vicente Vives-Peris, Jiaqi Zhao, Cuiyun Deng, Aurelio Gómez-Cadenas, Rubén Alcázar. Spermine deficiency shifts the balance between jasmonic acid and salicylic acid-mediated defence responses in Arabidopsis. Plant, cell & environment. 2023 Aug; ?(?):. doi: 10.1111/pce.14706. [PMID: 37651604]
  • Jinrong Wei, Aysha Arif Chahel, Yuan Ni, Xiaoyi Wei, Yuling Zhao, Ying Wang, Shaohua Zeng. Lycium RIN negatively modulate the biosynthesis of kukoamine A in hairy roots through decreasing thermospermine synthase expression. International journal of biological macromolecules. 2023 Aug; ?(?):126246. doi: 10.1016/j.ijbiomac.2023.126246. [PMID: 37567520]
  • Chen Jiang, Jun Shen, Chun Wang, Yongjie Huang, Linbo Wang, Yiran Yang, Wen Hu, Ping Li, Haiying Wu. Mechanism of aconitine mediated neuronal apoptosis induced by mitochondrial calcium overload caused by MCU. Toxicology letters. 2023 Jul; 384(?):86-95. doi: 10.1016/j.toxlet.2023.07.014. [PMID: 37506855]
  • Cheng-Wei Qiu, Ma Yue, Qing-Qing Wang, Man-Man Fu, Chengdao Li, Yizhou Wang, Feibo Wu. Barley HOMOCYSTEINE METHYLTRANSFERASE 2 confers drought tolerance by improving polyamine metabolism. Plant physiology. 2023 Jun; ?(?):. doi: 10.1093/plphys/kiad333. [PMID: 37300541]
  • Beibei Xie, Huichao Zhao, Yuan-Fu Ding, Ziyi Wang, Yan Wang, Cheng Gao, Ruibing Wang. Drug-free tumor therapy via spermine-responsive intracellular biomineralization. Journal of controlled release : official journal of the Controlled Release Society. 2023 May; 357(?):572-579. doi: 10.1016/j.jconrel.2023.04.018. [PMID: 37054780]
  • Marko Kebert, Saša Kostić, Srđan Stojnić, Eleonora Čapelja, Anđelina Gavranović Markić, Martina Zorić, Lazar Kesić, Victor Flors. A Fine-Tuning of the Plant Hormones, Polyamines and Osmolytes by Ectomycorrhizal Fungi Enhances Drought Tolerance in Pedunculate Oak. International journal of molecular sciences. 2023 Apr; 24(8):. doi: 10.3390/ijms24087510. [PMID: 37108671]
  • Ben-Xue Chen, Yan-Bing Li, Huai-Pan Liu, Ronald Kurtenbach. Putrescine transformation to other forms of polyamines in filling grain embryos functioned in enhancing the resistance of maize plants to drought stress. Plant physiology and biochemistry : PPB. 2023 Apr; 197(?):107654. doi: 10.1016/j.plaphy.2023.107654. [PMID: 36989984]
  • Gabriele Rocchetti, Annalisa Rebecchi, Constanza Maria Lopez, Michele Dallolio, Giuliano Dallolio, Marco Trevisan, Luigi Lucini. Impact of axenic and mixed starter cultures on metabolomic and sensory profiles of ripened Italian salami. Food chemistry. 2023 Feb; 402(?):134182. doi: 10.1016/j.foodchem.2022.134182. [PMID: 36126574]
  • Jakub Bělíček, Eva Ľuptáková, David Kopečný, Jan Frömmel, Armelle Vigouroux, Sanja Ćavar Zeljković, Franjo Jagic, Pierre Briozzo, David Jaroslav Kopečný, Petr Tarkowski, Jaroslav Nisler, Nuria De Diego, Solange Moréra, Martina Kopečná. Biochemical and structural basis of polyamine, lysine and ornithine acetylation catalyzed by spermine/spermidine N-acetyl transferase in moss and maize. The Plant journal : for cell and molecular biology. 2023 Feb; ?(?):. doi: 10.1111/tpj.16148. [PMID: 36786691]
  • Chopaka Thongbamrer, Purichaya Teerakantrakorn, Ussanee Nongpong, Nuttapon Apiratikul, Wanlapa Roobsoong, Nawapol Kunkeaw, Wang Nguitragool, Jetsumon Sattabongkot, Boon-Ek Yingyongnarongkul. In vitro transfection efficiencies of T-shaped spermine-based cationic lipids with identical and nonidentical tails under high serum conditions. Organic & biomolecular chemistry. 2023 Feb; ?(?):. doi: 10.1039/d2ob02129c. [PMID: 36762533]
  • Vishwanath Jogini, Morten Ø Jensen, David E Shaw. Gating and modulation of an inward-rectifier potassium channel. The Journal of general physiology. 2023 02; 155(2):. doi: 10.1085/jgp.202213085. [PMID: 36524993]
  • Foziya Altaf, Shazia Parveen, Sumira Farooq, Aehsan Ul Haq, Mohammad Lateef Lone, Inayatullah Tahir, Prashant Kaushik, Hamed A El-Serehy. Polyamines effectively mitigate senescence in persistent leaves of Berginia ciliata - a novel model system. Functional plant biology : FPB. 2023 02; 50(2):136-145. doi: 10.1071/fp21273. [PMID: 35144727]
  • Farwa Basit, Zaid Ulhassan, Qingshan Mou, Muhammad Mudassar Nazir, Jin Hu, Weimin Hu, Wenjian Song, Mohamed Salah Sheteiwy, Weijun Zhou, Javaid Akhter Bhat, Kaouthar Jeddi, Kamel Hessini, Yajing Guan. Seed priming with nitric oxide and/or spermine mitigate the chromium toxicity in rice (Oryza sativa) seedlings by improving the carbon-assimilation and minimising the oxidative damages. Functional plant biology : FPB. 2023 Feb; 50(2):121-135. doi: 10.1071/fp21268. [PMID: 35057906]
  • Salika Ramazan, Ifra Nazir, Waseem Yousuf, Riffat John. Environmental stress tolerance in maize (Zea mays): role of polyamine metabolism. Functional plant biology : FPB. 2023 02; 50(2):85-96. doi: 10.1071/fp21324. [PMID: 35300784]
  • Shaowei Sui, Hao Wang, Jiajie Song, Wanyi Tai. Development of a spermine lipid for transient antibody expression. Bioorganic & medicinal chemistry. 2023 01; 78(?):117114. doi: 10.1016/j.bmc.2022.117114. [PMID: 36563514]
  • Mehdi Afrouz, Farnaz Ahmadi-Nouraldinvand, Sabry G Elias, Mohammad Taghi Alebrahim, Te Ming Tseng, Hoda Zahedian. Green synthesis of spermine coated iron nanoparticles and its effect on biochemical properties of Rosmarinus officinalis. Scientific reports. 2023 01; 13(1):775. doi: 10.1038/s41598-023-27844-5. [PMID: 36641537]
  • Liangchen Zhang, Yaxun Fan, Luciano Galantini, Karin Schillén, Alessandra Del Giudice, Guanqun Du, Yilin Wang. Noncovalent Bile Acid Oligomers as Facial Amphiphilic Antimicrobials. Langmuir : the ACS journal of surfaces and colloids. 2023 01; 39(1):495-506. doi: 10.1021/acs.langmuir.2c02787. [PMID: 36529944]
  • Chi Zhang, Kostadin E Atanasov, Rubén Alcázar. Spermine inhibits PAMP-induced ROS and Ca2+ burst and reshapes the transcriptional landscape of PAMP-triggered immunity in Arabidopsis. Journal of experimental botany. 2023 01; 74(1):427-442. doi: 10.1093/jxb/erac411. [PMID: 36264272]
  • Xilong Li, Zongyun Yan, Meiling Zhang, Jiayin Wang, Peiyong Xin, Shujing Cheng, Liquan Kou, Xiaoting Zhang, Songlin Wu, Jinfang Chu, Chengqi Yi, Keqiong Ye, Bing Wang, Jiayang Li. SnoRNP is essential for thermospermine-mediated development in Arabidopsis thaliana. Science China. Life sciences. 2023 01; 66(1):2-11. doi: 10.1007/s11427-022-2235-4. [PMID: 36385591]
  • Mehdi Afrouz, Amin Amani, Ali Eftekhari, Christophe Coudret, Sabry G Elias, Zainab Ahmadian, Mohammad Taghi Alebrahim. Design and synthesis of multi-targeted nanoparticles for gene delivery to breast cancer tissues. Naunyn-Schmiedeberg's archives of pharmacology. 2023 01; 396(1):121-137. doi: 10.1007/s00210-022-02303-6. [PMID: 36255459]
  • Hemanjali Mude, Aniket Balapure, Anindita Thakur, Ramakrishnan Ganesan, Jayati Ray Dutta. Enhanced antibacterial, antioxidant and anticancer activity of caffeic acid by simple acid-base complexation with spermine/spermidine. Natural product research. 2022 Dec; 36(24):6453-6458. doi: 10.1080/14786419.2022.2038597. [PMID: 35142575]
  • Sachie Nakatani, Yasuhiro Horimoto, Natsumi Nakabayashi, Mayumi Karasawa, Masahiro Wada, Kenji Kobata. Spermine Suppresses Adipocyte Differentiation and Exerts Anti-Obesity Effects In Vitro and In Vivo. International journal of molecular sciences. 2022 Oct; 23(19):. doi: 10.3390/ijms231911818. [PMID: 36233120]
  • Zoltán Takács, Zalán Czékus, Irma Tari, Péter Poór. The role of ethylene signalling in the regulation of salt stress response in mature tomato fruits: Metabolism of antioxidants and polyamines. Journal of plant physiology. 2022 Oct; 277(?):153793. doi: 10.1016/j.jplph.2022.153793. [PMID: 35995003]
  • Qing Zhang, Meixia Liang, Ruoxuan Song, Zhizhong Song, Hao Song, Xuqiang Qiao. Brassinosteroids enhance resistance to manganese toxicity in Malus robusta Rehd. via modulating polyamines profile. Journal of plant physiology. 2022 Oct; 277(?):153808. doi: 10.1016/j.jplph.2022.153808. [PMID: 36088781]
  • Xin Mei, Liuhong Hu, Yuyan Song, Caibi Zhou, Ren Mu, Xintai Xie, Jing Li, Lan Xiang, Qingbei Weng, Ziyin Yang. Heterologous Expression and Characterization of Tea (Camellia sinensis) Polyamine Oxidase Homologs and Their Involvement in Stresses. Journal of agricultural and food chemistry. 2022 Sep; 70(38):11880-11891. doi: 10.1021/acs.jafc.2c01549. [PMID: 36106904]
  • Tian Wang, Boya Hao, Shilin Xu, Jie Meng, Tao Wen, Jian Liu, Haiyan Xu. Effective RNAi in leukemia cells is enhanced by spermine-modified pullulan combined with desloratadine. Carbohydrate polymers. 2022 Sep; 292(?):119646. doi: 10.1016/j.carbpol.2022.119646. [PMID: 35725203]
  • Jianwei Zhang, Le Liang, Jiachang Xiao, Yongdong Xie, Li Zhu, Xinru Xue, Linyu Xu, Peihan Zhou, Jianzhao Ran, Zhi Huang, Guochao Sun, Yunsong Lai, Bo Sun, Yi Tang, Huanxiu Li. Genome-Wide Identification of Polyamine Oxidase (PAO) Family Genes: Roles of CaPAO2 and CaPAO4 in the Cold Tolerance of Pepper (Capsicum annuum L.). International journal of molecular sciences. 2022 Sep; 23(17):. doi: 10.3390/ijms23179999. [PMID: 36077395]
  • Xiuxiu Liu, Mingjing Wang, Yao Song, Chaoqun Zhang, Yonghong Jiang, Wen Li, Binbin Xu, Zhiyan Jiang. Kukoamine A inhibits C-C motif chemokine receptor 5 to attenuate lipopolysaccharide-induced lung injury. Drug development research. 2022 09; 83(6):1455-1466. doi: 10.1002/ddr.21975. [PMID: 35862278]
  • Valentina Buffagni, Leilei Zhang, Biancamaria Senizza, Gabriele Rocchetti, Andrea Ferrarini, Begoña Miras-Moreno, Luigi Lucini. Metabolomics and lipidomics insight into the effect of different polyamines on tomato plants under non-stress and salinity conditions. Plant science : an international journal of experimental plant biology. 2022 Sep; 322(?):111346. doi: 10.1016/j.plantsci.2022.111346. [PMID: 35697150]
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