Citric acid (BioDeep_00000000304)

 

Secondary id: BioDeep_00000229672, BioDeep_00000400016, BioDeep_00000400390

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


2-hydroxypropane-1,2,3-tricarboxylic acid

化学式: C6H8O7 (192.027)
中文名称: 无水柠檬酸, 柠檬酸
谱图信息: 最多检出来源 Homo sapiens(blood) 23.58%

Reviewed

Last reviewed on 2024-07-01.

Cite this Page

Citric acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/citric_acid (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000304). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C(C(=O)O)C(CC(=O)O)(C(=O)O)O
InChI: InChI=1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

描述信息

Citric acid (citrate) is a tricarboxylic acid, an organic acid with three carboxylate groups. Citrate is an intermediate in the TCA cycle (also known as the Tricarboxylic Acid cycle, the Citric Acid cycle or Krebs cycle). The TCA cycle is a central metabolic pathway for all animals, plants, and bacteria. As a result, citrate is found in all living organisms, from bacteria to plants to animals. In the TCA cycle, the enzyme citrate synthase catalyzes the condensation of oxaloacetate with acetyl CoA to form citrate. Citrate then acts as the substrate for the enzyme known as aconitase and is then converted into aconitic acid. The TCA cycle ends with regeneration of oxaloacetate. This series of chemical reactions in the TCA cycle is the source of two-thirds of the food-derived energy in higher organisms. Citrate can be transported out of the mitochondria and into the cytoplasm, then broken down into acetyl-CoA for fatty acid synthesis, and into oxaloacetate. Citrate is a positive modulator of this conversion, and allosterically regulates the enzyme acetyl-CoA carboxylase, which is the regulating enzyme in the conversion of acetyl-CoA into malonyl-CoA (the commitment step in fatty acid synthesis). In short, citrate is transported into the cytoplasm, converted into acetyl CoA, which is then converted into malonyl CoA by acetyl CoA carboxylase, which is allosterically modulated by citrate. In mammals and other vertebrates, Citrate is a vital component of bone, helping to regulate the size of apatite crystals (PMID: 21127269). Citric acid is found in citrus fruits, most concentrated in lemons and limes, where it can comprise as much as 8\\\\\% of the dry weight of the fruit. Citric acid is a natural preservative and is also used to add an acidic (sour) taste to foods and carbonated drinks. Because it is one of the stronger edible acids, the dominant use of citric acid is as a flavoring and preservative in food and beverages, especially soft drinks and candies. Citric acid is an excellent chelating agent, binding metals by making them soluble. It is used to remove and discourage the buildup of limescale from boilers and evaporators. It can be used to treat water, which makes it useful in improving the effectiveness of soaps and laundry detergents. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability. Intolerance to citric acid in the diet is known to exist. Little information is available as the condition appears to be rare, but like other types of food intolerance it is often described as a "pseudo-allergic" reaction.
Citric acid appears as colorless, odorless crystals with an acid taste. Denser than water. (USCG, 1999)
Citric acid is a tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms. It has a role as a food acidity regulator, a chelator, an antimicrobial agent and a fundamental metabolite. It is a conjugate acid of a citrate(1-) and a citrate anion.
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.
Citric acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Anhydrous citric acid is a Calculi Dissolution Agent and Anti-coagulant. The mechanism of action of anhydrous citric acid is as an Acidifying Activity and Calcium Chelating Activity. The physiologic effect of anhydrous citric acid is by means of Decreased Coagulation Factor Activity.
Anhydrous Citric Acid is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients and is used as a preservative. It is also used as an acidulant to control pH and acts as an anticoagulant by chelating calcium in blood.
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
See also: Citric Acid Monohydrate (related).
Citrate, also known as anhydrous citric acid or 2-hydroxy-1,2,3-propanetricarboxylic acid, belongs to tricarboxylic acids and derivatives class of compounds. Those are carboxylic acids containing exactly three carboxyl groups. Citrate is soluble (in water) and a weakly acidic compound (based on its pKa). Citrate can be found in a number of food items such as ucuhuba, loquat, bayberry, and longan, which makes citrate a potential biomarker for the consumption of these food products. Citrate can be found primarily in most biofluids, including saliva, sweat, feces, and blood, as well as throughout all human tissues. Citrate exists in all living species, ranging from bacteria to humans. In humans, citrate is involved in several metabolic pathways, some of which include the oncogenic action of succinate, the oncogenic action of fumarate, the oncogenic action of 2-hydroxyglutarate, and congenital lactic acidosis. Citrate is also involved in several metabolic disorders, some of which include 2-ketoglutarate dehydrogenase complex deficiency, pyruvate dehydrogenase deficiency (E2), fumarase deficiency, and glutaminolysis and cancer. Moreover, citrate is found to be associated with lung Cancer, tyrosinemia I, maple syrup urine disease, and propionic acidemia. A citrate is a derivative of citric acid; that is, the salts, esters, and the polyatomic anion found in solution. An example of the former, a salt is trisodium citrate; an ester is triethyl citrate. When part of a salt, the formula of the citrate ion is written as C6H5O73− or C3H5O(COO)33− .
A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.

Citric acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=77-92-9 (retrieved 2024-07-01) (CAS RN: 77-92-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[1][2][3].
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[1][2][3].

同义名列表

158 个代谢物同义名

Citric acid, Anhydrous, Pharmaceutical Secondary Standard; Certified Reference Material; InChI=1/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12; Citric acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99.5\\%; CITRIC ACID (CONSTITUENT OF GARCINIA CAMBOGIA AND GARCINIA INDICA) [DSC]; Citric acid, anhydrous, cell culture tested, plant cell culture tested; Citric acid, anhydrous, European Pharmacopoeia (EP) Reference Standard; CITRIC ACID (CONSTITUENT OF GARCINIA CAMBOGIA AND GARCINIA INDICA); Citric acid, United States Pharmacopeia (USP) Reference Standard; Citric Acid Anhydrous; 2-Hydroxypropane-1,2,3-tricarboxylic acid; CITRIC ACID (CONSTITUENT OF CRANBERRY LIQUID PREPARATION) [DSC]; CITRIC ACID (CONSTITUENT OF CRANBERRY LIQUID PREPARATION); Citric acid, meets USP testing specifications, anhydrous; 1,2,3-PROPANETRICARBOXYLIC ACID,2-HYDROXY (CITRIC ACID); Citric acid, certified reference material, TraceCERT(R); 2-Hydroxy-1,2,3-propanetricarboxylic Acid, Anhydrous; Kyselina 2-hydroxy-1,2,3-propantrikarbonova [Czech]; 1,2,3-Propanetricarboxylic acid, 2-hydroxy- (9CI); Citric acid, BioUltra, anhydrous, >=99.5\\% (T); 4-03-00-01272 (Beilstein Handbook Reference); 2-Hydroxy-1,2,3-propanenetricarboxylic acid; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-; Kyselina 2-hydroxy-1,2,3-propantrikarbonova; 2-Hydroxy-1,2,3-propane tricarboxylic acid; 2-hydroxy-1,2,3-propane-tricarboxylic acid; ANHYDROUS CITRIC ACID COMPONENT OF CLENPIQ; Citric acid, Vetec(TM) reagent grade, 99\\%; 3-Carboxy-3-hydroxypentane-1,5-dioic acid; 2-hydroxypropane-1,2,3-tricarboxylic acid; 1,3-Propanetricarboxylic acid, 2-hydroxy-; 2-hydroxy-1,2,3-propanetricarboxylic acid; 2-hydroxy-1,2,3-propanetricarboxyic acid; 2-hydroxypropane-1,2,3-tricarboxylicacid; Citric Acid, anhydrous granular, A.C.S.; CLENPIQ COMPONENT ANHYDROUS CITRIC ACID; 2-Hydroxy-1,3-propanetricarboxylic acid; Citric acid, SAJ first grade, >=99.5\\%; 2-hydroxy-1,2,3-propanetricarboxylate; ANHYDROUS CITRIC ACID (USP MONOGRAPH); ANHYDROUS CITRIC ACID [USP MONOGRAPH]; CITRIC ACID, ANHYDROUS [USP IMPURITY]; CITRIC ACID, ANHYDROUS (USP IMPURITY); Citric Acid, anhydrous powder, A.C.S.; 3-Carboxy-3-hydroxypentane-1,5-dioate; 8F5D336A-442D-434A-9FB0-E400FF74E343; CITRIC ACID, ANHYDROUS (EP IMPURITY); CITRIC ACID, ANHYDROUS [EP IMPURITY]; Citric acid, LR, anhydrous, >=99\\%; 2-Hydroxypropanetricarboxylic acid; Citric acid, Electrophoresis Grade; Citric acid, ACS reagent, >=99.5\\%; .beta.-Hydroxytricarballylic acid; Citric acid, anhydrous [USP:JAN]; Citric acid, analytical standard; beta-Hydroxytricarballylic acid; CITRIC ACID, ANHYDROUS [WHO-IP]; BETA-HYDROXY-TRICARBOXYLIC ACID; Citric acid, >=99.5\\%, FCC, FG; ACIDUM CITRICUM [WHO-IP LATIN]; ANHYDROUS CITRIC ACID [MART.]; ANHYDROUS CITRIC ACID (MART.); CITRIC ACID,ANHYDROUS [VANDF]; Citric acid, anhydrous (USP); 2-Hydroxytricarballylic acid; Anhydrous citric acid (JP17); Citric acid anhydrous (JAN); ANHYDROUS CITRIC ACID [JAN]; Acidum citricum monohydrate; beta-Hydroxytricarballylate; Citric Acid, anhydrous, USP; ANHYDROUS CITRIC ACID [II]; Kyselina citronova [Czech]; ANHYDROUS CITRIC ACID (II); Citric acid, p.a., 99.5\\%; Citric acid monoglyceride; Monohydrate, citric acid; Acid monohydrate, citric; 2-Hydroxytricarballylate; Citric Acid Monohydrate; CITRICUM ACIDUM [HPUS]; Citric acid [USAN:JAN]; Citric acid, anhydrous; Anhydrous citric acid; Citric acid anhydrous; Citric acid,anhydrous; Citraclean (Salt/Mix); K-Lyte/Cl (Salt/Mix); CITRIC ACID [WHO-DD]; K-Lyte DS (Salt/Mix); Kyselina citronova; CITRIC ACID [FHFI]; CITRIC ACID [HSDB]; Citric acid, 99\\%; K-Lyte (Salt/Mix); Anhydrous citrate; Citrate anhydrous; Citric acid (8CI); HOC(CH2COOH)2COOH; NCIStruc2_000099; CITRIC ACID [MI]; NCIStruc1_000057; Spectrum3_001850; WLN: QV1XQVQ1VQ; Citric Acid,(S); NCIOpen2_004502; Citricum acidum; NCIOpen2_004062; Acidum citricum; Citronensaeure; Oprea1_502996; Citronensaure; CITRATE ANION; acido citrico; Hydrocerol A; KBio3_002740; NCI60_022579; Tox21_113436; Tox21_300124; Tox21_202405; Citric Acid; Uro-trainer; citric-acid; CAS-77-92-9; Citraclean; K-Lyte DS; Aciletten; AI3-06286; Citralite; UBIQUITIN; Citretten; Uralyt U; Chemfill; Citrate; C6H8O7; Citric; Suby G; K-Lyte; H3cit; e 330; Citro; 2fwp; 4to8; 2fw6; 4nrm; e330; 4o61; citr; 1y4a; 1i2s; 1rq2; 1o4l; 2c4v; 4aci; 2bo4; β-Hydroxytricarballylic acid; β-Hydroxytricarballylate; Citric acid; Citrate; Citric acid



数据库引用编号

44 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(17)

BioCyc(2)

PlantCyc(0)

代谢反应

573 个相关的代谢反应过程信息。

Reactome(154)

BioCyc(8)

WikiPathways(5)

Plant Reactome(401)

INOH(5)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

349 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ACLY, ALB, CA3, CAT, ELANE, FH, GAPDH, PC, PKM
Peripheral membrane protein 1 HSD17B6
Nucleus 5 ALB, CS, FH, GAPDH, PKM
cytosol 11 ACLY, ACO2, ALB, CA3, CAT, ELANE, FH, GAPDH, LIPE, PC, PKM
phagocytic vesicle 1 ELANE
centrosome 1 ALB
nucleoplasm 2 ACLY, ATP2B1
Cell membrane 3 ATP2B1, LIPE, TRPV1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 3 ATP2B1, ATP4A, TRPV1
Synapse 1 ATP2B1
cell surface 1 ELANE
glutamatergic synapse 1 ATP2B1
Golgi apparatus 2 ALB, ATRN
Golgi membrane 1 INS
neuronal cell body 1 TRPV1
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 3 ACLY, GAPDH, LIPE
plasma membrane 6 ATP2B1, ATP4A, ATRN, GAPDH, KNG1, TRPV1
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ACLY, ATP2B1, ATP4A, CAT, CS, GAPDH, LIPE, TRPV1
apical plasma membrane 1 ATP4A
basolateral plasma membrane 1 ATP2B1
caveola 1 LIPE
extracellular exosome 12 ACLY, ALB, ATP2B1, ATRN, BMP3, CAT, CS, ELANE, FH, GAPDH, KNG1, PKM
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 ALB, HSD17B6
extracellular space 7 ALB, ATP4A, ATRN, BMP3, ELANE, INS, KNG1
perinuclear region of cytoplasm 1 GAPDH
mitochondrion 6 ACO2, CAT, CS, FH, PC, PKM
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 4 ATP2B1, CAT, GAPDH, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 1 ATRN
Secreted 3 ALB, BMP3, INS
extracellular region 8 ACLY, ALB, BMP3, CAT, ELANE, INS, KNG1, PKM
[Isoform 2]: Secreted 1 ATRN
Mitochondrion matrix 2 CS, PC
mitochondrial matrix 5 ACO2, CAT, CS, FH, PC
anchoring junction 1 ALB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
nuclear membrane 1 GAPDH
external side of plasma membrane 1 TRPV1
Extracellular vesicle 1 PKM
microtubule cytoskeleton 1 GAPDH
vesicle 2 GAPDH, PKM
postsynaptic membrane 1 TRPV1
Apical cell membrane 1 ATP4A
Cytoplasm, perinuclear region 1 GAPDH
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 1 CAT
GABA-ergic synapse 1 TRPV1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 3 ELANE, KNG1, PKM
secretory granule 1 ELANE
lateral plasma membrane 1 ATP2B1
Postsynaptic cell membrane 1 TRPV1
Cell projection, neuron projection 1 TRPV1
ciliary basal body 1 ALB
cilium 1 PKM
cell projection 1 ATP2B1
Chromosome 1 FH
cytoskeleton 1 GAPDH
centriole 1 ALB
Secreted, extracellular space 1 KNG1
spindle pole 1 ALB
blood microparticle 2 ALB, KNG1
Basolateral cell membrane 1 ATP2B1
site of double-strand break 1 FH
[Isoform 3]: Secreted 1 ATRN
endosome lumen 1 INS
Lipid droplet 2 GAPDH, LIPE
Membrane, caveola 1 LIPE
Presynaptic cell membrane 1 ATP2B1
ficolin-1-rich granule lumen 3 ACLY, CAT, PKM
secretory granule lumen 3 CAT, INS, PKM
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, INS, KNG1
transcription repressor complex 1 ELANE
platelet alpha granule lumen 2 ALB, KNG1
specific granule lumen 1 ELANE
transport vesicle 1 INS
azurophil granule lumen 2 ACLY, ELANE
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
ribonucleoprotein complex 1 GAPDH
[Isoform 1]: Cell membrane 1 ATRN
Rough endoplasmic reticulum 1 PKM
Cytoplasmic vesicle, phagosome 1 ELANE
GAIT complex 1 GAPDH
Cell projection, dendritic spine membrane 1 TRPV1
dendritic spine membrane 1 TRPV1
catalase complex 1 CAT
[Isoform Mitochondrial]: Mitochondrion 1 FH
[Isoform Cytoplasmic]: Cytoplasm, cytosol 1 FH
photoreceptor ribbon synapse 1 ATP2B1
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
potassium:proton exchanging ATPase complex 1 ATP4A
ciliary transition fiber 1 ALB


文献列表

  • Guofei Liu, Lingfei Hu, Caixian Tang, Jianming Xu. Changes in the extractability and fractionation of cadmium and copper in a contaminated soil amended with various sugarcane bagasse-based materials. Ecotoxicology and environmental safety. 2024 Jun; 278(?):116443. doi: 10.1016/j.ecoenv.2024.116443. [PMID: 38744068]
  • Donglin Xin, Hong Yin, Ganqiao Ran. Efficient production of High-Purity manno-oligosaccharides from guar gum by citric acid and enzymatic hydrolysis. Bioresource technology. 2024 Jun; 401(?):130719. doi: 10.1016/j.biortech.2024.130719. [PMID: 38642662]
  • Sunita Ranote, Marek Kowalczuk, Natalia Guzenko, Khadar Duale, Paweł Chaber, Marta Musioł, Andrzej Jankowski, Andrzej Marcinkowski, Piotr Kurcok, Ghanshyam S Chauhan, Sandeep Chauhan, Kiran Kumar. Towards scalable and degradable bioplastic films from Moringa oleifera gum/poly(vinyl alcohol) as packaging material. International journal of biological macromolecules. 2024 Jun; 269(Pt 2):132219. doi: 10.1016/j.ijbiomac.2024.132219. [PMID: 38729475]
  • Meng-Yu Liu, Xu-Feng Luo, Jiao-Feng Gu, Xuan-Tao Yi, Hang Zhou, Peng Zeng, Bo-Han Liao. [Cadmium Phytoremediation Effect of Sweet Sorghum Assisted with Citric Acid on Typical Parent Soil in Southern China]. Huan jing ke xue= Huanjing kexue. 2024 May; 45(5):3016-3026. doi: 10.13227/j.hjkx.202306027. [PMID: 38629562]
  • Xiaona Wang, Yan Zhou, Xiaofen Chai, Toshi M Foster, Cecilia H Deng, Ting Wu, Xinzhong Zhang, Zhenhai Han, Yi Wang. miR164-MhNAC1 regulates apple root nitrogen uptake under low nitrogen stress. The New phytologist. 2024 May; 242(3):1218-1237. doi: 10.1111/nph.19663. [PMID: 38481030]
  • Hongyu Li, Zheng Li, Pengwang Wang, Zheng Liu, Lingzhuo An, Xuemin Zhang, Zhouyi Xie, Yingping Wang, Xia Li, Wenyuan Gao. Evaluation of citrus pectin extraction methods: Synergistic enhancement of pectin's antioxidant capacity and gel properties through combined use of organic acids, ultrasonication, and microwaves. International journal of biological macromolecules. 2024 May; 266(Pt 1):131164. doi: 10.1016/j.ijbiomac.2024.131164. [PMID: 38547940]
  • Xiaochuan Ma, Ling Sheng, Feifei Li, Tie Zhou, Jing Guo, Yuanyuan Chang, Junfeng Yang, Yan Jin, Yuewen Chen, Xiaopeng Lu. Seasonal drought promotes citrate accumulation in citrus fruit through the CsABF3-activated CsAN1-CsPH8 pathway. The New phytologist. 2024 May; 242(3):1131-1145. doi: 10.1111/nph.19671. [PMID: 38482565]
  • Shan Huang, Guangfeng Sun, Penglong Wu, LinJing Wu, Hongfei Jiang, Xixing Wang, Liyuan Li, Lingling Gao, Fanqi Meng. Safety and Feasibility of Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy With Calcium-Containing Solutions: A Randomized Controlled Trial. Seminars in dialysis. 2024 May; 37(3):249-258. doi: 10.1111/sdi.13200. [PMID: 38439685]
  • Mengying Chen, Shizhong Feng, He Lv, Zewen Wang, Yuhang Zeng, Caihong Shao, Wenxiong Lin, Zhixing Zhang. OsCIPK2 mediated rice root microorganisms and metabolites to improve plant nitrogen uptake. BMC plant biology. 2024 Apr; 24(1):285. doi: 10.1186/s12870-024-04982-0. [PMID: 38627617]
  • Agnieszka Tomczyk-Warunek, Karolina Turżańska, Agnieszka Posturzyńska, Filip Kowal, Tomasz Blicharski, Inés Torné Pano, Anna Winiarska-Mieczan, Anna Nikodem, Sławomir Dresler, Ireneusz Sowa, Magdalena Wójciak, Piotr Dobrowolski. Influence of Various Strontium Formulations (Ranelate, Citrate, and Chloride) on Bone Mineral Density, Morphology, and Microarchitecture: A Comparative Study in an Ovariectomized Female Mouse Model of Osteoporosis. International journal of molecular sciences. 2024 Apr; 25(7):. doi: 10.3390/ijms25074075. [PMID: 38612883]
  • Zhiqi Gao, Xiangchun Quan, Yu Zheng, Ruoyu Yin, Kai Lv. Comparative investigations on the incorporation of biogenic Fe products into anaerobic granular sludge of different sources: Fe loading capacity, physicochemical properties, microbial community and long-term methanogenesis performance. Journal of environmental management. 2024 Apr; 356(?):120546. doi: 10.1016/j.jenvman.2024.120546. [PMID: 38471321]
  • Léa Mounier, Mathieu Pédrot, Martine Bouhnik-Le-Coz, Francisco Cabello-Hurtado. Iron oxide nanoparticles improving multimetal phytoextraction in Helianthus annuus. Chemosphere. 2024 Apr; 353(?):141534. doi: 10.1016/j.chemosphere.2024.141534. [PMID: 38403123]
  • Yu-Lei Jia, Ying Zhang, Lu-Wei Xu, Zi-Xu Zhang, Ying-Shuang Xu, Wang Ma, Yang Gu, Xiao-Man Sun. Enhanced fatty acid storage combined with the multi-factor optimization of fermentation for high-level production of docosahexaenoic acid in Schizochytrium sp. Bioresource technology. 2024 Apr; 398(?):130532. doi: 10.1016/j.biortech.2024.130532. [PMID: 38447618]
  • Maria Gracheva, Zoltán Klencsár, Zoltán Homonnay, Ádám Solti, László Péter, Libor Machala, Petr Novak, Krisztina Kovács. Revealing the nuclearity of iron citrate complexes at biologically relevant conditions. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2024 Apr; 37(2):461-475. doi: 10.1007/s10534-023-00562-1. [PMID: 38110781]
  • Ruchi Rani, Laxmikant S Badwaik. Synergistic impact of natural gums and crosslinkers on the properties of oilseed meals based biopolymeric films. International journal of biological macromolecules. 2024 Apr; 265(Pt 1):130809. doi: 10.1016/j.ijbiomac.2024.130809. [PMID: 38493819]
  • Chunhou Li, Xican Li, Jingyuan Zeng, Rongxin Cai, Shaoman Chen, Ban Chen, Xiaojun Zhao. Detection of Adulterated Naodesheng Tablet (Naodesheng Pian) via In-Depth Chemical Analysis and Subsequent Reconstruction of Its Pharmacopoeia Q-Markers. Molecules (Basel, Switzerland). 2024 Mar; 29(6):. doi: 10.3390/molecules29061392. [PMID: 38543029]
  • Wei-Lin Ren, Cheng-Zhi Li, Abid Ullah, Xiao-Zhang Yu. Boron deficiency decreased the root activity of Ga-exposed rice seedlings by reducing iron accumulation and increasing Ga in iron plaque. Ecotoxicology (London, England). 2024 Mar; 33(2):142-150. doi: 10.1007/s10646-024-02731-5. [PMID: 38282122]
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