Pratensein (BioDeep_00000008133)
human metabolite PANOMIX_OTCML-2023 Endogenous natural product
代谢物信息卡片
化学式: C16H12O6 (300.0634)
中文名称: 红车轴草素
谱图信息:
最多检出来源 Homo sapiens(plant) 8.97%
分子结构信息
SMILES: c1(cc(c2c(c1)occ(c2=O)c1cc(c(cc1)OC)O)O)O
InChI: InChI=1S/C16H12O6/c1-21-13-3-2-8(4-11(13)18)10-7-22-14-6-9(17)5-12(19)15(14)16(10)20/h2-7,17-19H,1H3
描述信息
Pratensein is a member of the class of 7-hydroxyisoflavones in which isoflavone is substituted by hydroxy groups at the 5, 7, and 3 positions, and by a methoxy group at the 4 position. It is a member of 7-hydroxyisoflavones and a member of 4-methoxyisoflavones. It is a conjugate acid of a pratensein(1-).
Pratensein is a natural product found in Dalbergia sissoo, Cicer chorassanicum, and other organisms with data available.
See also: Trifolium pratense flower (part of).
A member of the class of 7-hydroxyisoflavones in which isoflavone is substituted by hydroxy groups at the 5, 7, and 3 positions, and by a methoxy group at the 4 position.
Constituent of Cicer arietinum (chickpea). 3-Hydroxybiochanin A is found in peanut, chickpea, and pulses.
Pratensein is found in chickpea. Pratensein is a constituent of Cicer arietinum (chickpea)
同义名列表
17 个代谢物同义名
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-; 5,7-Dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one; 5,7-dihydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one; 5,7,3-trihydroxy-4-methoxyisoflavone; 4-methoxy-3,5,7-trihydroxyisoflavone; 3,5,7-trihydroxy-4-methoxyisoflavone; 3-hydroxy-biochanin A; 3-hydroxybiochanin A; PRATENSEIN [MI]; UNII-D2CF8CJ6AP; 4776b Compound; D2CF8CJ6AP; Pratensein; pratensin; MT-8; Pratensein
数据库引用编号
23 个数据库交叉引用编号
- ChEBI: CHEBI:8359
- KEGG: C10520
- PubChem: 5281803
- HMDB: HMDB0030617
- Metlin: METLIN47772
- ChEMBL: CHEMBL252904
- Wikipedia: Pratensein
- LipidMAPS: LMPK12050265
- MeSH: 4-methoxy-3,5,7-trihydroxyisoflavone
- ChemIDplus: 0002284313
- MetaCyc: CPD-3622
- KNApSAcK: C00002563
- foodb: FDB002514
- chemspider: 4445115
- CAS: 2284-31-3
- medchemexpress: HY-N7981
- PMhub: MS000021694
- MetaboLights: MTBLC8359
- PubChem: 12703
- 3DMET: B03922
- NIKKAJI: J7.387C
- LOTUS: LTS0255186
- KNApSAcK: 8359
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
121 个相关的物种来源信息
- 3563 - Amaranthaceae: LTS0255186
- 111850 - Ammopiptanthus: LTS0255186
- 126911 - Ammopiptanthus mongolicus: 10.1002/HLCA.200890108
- 126911 - Ammopiptanthus mongolicus: LTS0255186
- 48128 - Andira: LTS0255186
- 53825 - Andira inermis: 10.1016/S0378-8741(00)00285-3
- 53825 - Andira inermis: LTS0255186
- 588922 - Andira surinamensis: 10.1002/MRC.2138
- 588922 - Andira surinamensis: LTS0255186
- 3817 - Arachis: LTS0255186
- 3818 - Arachis hypogaea: 10.1248/YAKUSHI1947.103.9_997
- 3818 - Arachis hypogaea: LTS0255186
- 20400 - Astragalus: LTS0255186
- 649199 - Astragalus membranaceus: 10.1002/MRC.1806
- 649199 - Astragalus membranaceus: LTS0255186
- 119829 - Astragalus mongholicus: 10.1002/MRC.1806
- 119829 - Astragalus mongholicus: LTS0255186
- 3084394 - Astragalus trimestris: LTS0255186
- 83153 - Bassia: LTS0255186
- 83154 - Bassia scoparia: LTS0255186
- 53837 - Bolusanthus: LTS0255186
- 53838 - Bolusanthus speciosus: 10.1515/ZNC-1985-9-1005
- 53838 - Bolusanthus speciosus: LTS0255186
- 37411 - Bryaceae: LTS0255186
- 3208 - Bryophyta: LTS0255186
- 3214 - Bryopsida: LTS0255186
- 37412 - Bryum: LTS0255186
- 149638 - Calia: LTS0255186
- 2816358 - Chesniella: LTS0255186
- 3826 - Cicer: 10.1007/BF00629810
- 3826 - Cicer: LTS0255186
- 242878 - Cicer anatolicum: 10.1016/S0031-9422(97)00798-X
- 242878 - Cicer anatolicum: LTS0255186
- 3827 - Cicer arietinum:
- 3827 - Cicer arietinum: 10.1002/JPS.2600640504
- 3827 - Cicer arietinum: 10.1007/BF00629810
- 3827 - Cicer arietinum: 10.1016/0031-9422(95)00618-4
- 3827 - Cicer arietinum: 10.1016/S0021-9673(01)96392-7
- 3827 - Cicer arietinum: 10.1016/S0031-9422(97)00798-X
- 3827 - Cicer arietinum: 10.1515/ZNC-1987-11-1206
- 3827 - Cicer arietinum: LTS0255186
- 90899 - Cicer bijugum: 10.1016/S0031-9422(97)00798-X
- 90899 - Cicer bijugum: LTS0255186
- 200948 - Cicer canariense: 10.1016/S0031-9422(97)00798-X
- 200948 - Cicer canariense: LTS0255186
- 107682 - Cicer chorassanicum: 10.1016/S0031-9422(97)00798-X
- 107682 - Cicer chorassanicum: LTS0255186
- 92720 - Cicer cuneatum: 10.1016/S0031-9422(97)00798-X
- 92720 - Cicer cuneatum: LTS0255186
- 90897 - Cicer echinospermum: 10.1016/S0031-9422(97)00798-X
- 90897 - Cicer echinospermum: LTS0255186
- 242867 - Cicer flexuosum: 10.1007/BF00629810
- 242867 - Cicer flexuosum: LTS0255186
- 92719 - Cicer judaicum: 10.1016/S0031-9422(97)00798-X
- 92719 - Cicer judaicum: LTS0255186
- 200949 - Cicer macracanthum: 10.1016/S0031-9422(97)00798-X
- 200949 - Cicer macracanthum: LTS0255186
- 224826 - Cicer microphyllum: 10.1016/S0031-9422(97)00798-X
- 224826 - Cicer microphyllum: LTS0255186
- 242870 - Cicer nuristanicum: 10.1016/S0031-9422(97)00798-X
- 242870 - Cicer nuristanicum: LTS0255186
- 242871 - Cicer oxyodon: 10.1016/S0031-9422(97)00798-X
- 242871 - Cicer oxyodon: LTS0255186
- 242872 - Cicer pungens: 10.1007/BF00629810
- 242872 - Cicer pungens: LTS0255186
- 242873 - Cicer songaricum: 10.1007/BF00629811
- 242873 - Cicer songaricum: LTS0255186
- 242877 - Cicer tragacanthoides: 10.1007/BF00629810
- 242877 - Cicer tragacanthoides: LTS0255186
- 92718 - Cicer yamashitae: 10.1016/S0031-9422(97)00798-X
- 92718 - Cicer yamashitae: LTS0255186
- 53862 - Dalbergia: LTS0255186
- 1353466 - Dalbergia parviflora: 10.1021/NP900676Y
- 1353466 - Dalbergia parviflora: LTS0255186
- 107308 - Dalbergia sissoo: 10.1016/J.BMCL.2011.12.036
- 107308 - Dalbergia sissoo: LTS0255186
- 2231446 - Dermatophyllum: LTS0255186
- 149639 - Dermatophyllum secundiflorum:
- 149639 - Dermatophyllum secundiflorum: 10.1016/0031-9422(95)93530-S
- 149639 - Dermatophyllum secundiflorum: 10.1016/S0031-9422(96)00582-1
- 149639 - Dermatophyllum secundiflorum: 10.1055/S-0029-1185944
- 149639 - Dermatophyllum secundiflorum: LTS0255186
- 228657 - Echinosophora: LTS0255186
- 228658 - Echinosophora koreensis: 10.1016/0031-9422(92)83646-G
- 228658 - Echinosophora koreensis: LTS0255186
- 2759 - Eukaryota: LTS0255186
- 3803 - Fabaceae: LTS0255186
- 9606 - Homo sapiens: -
- 26339 - Iridaceae: LTS0255186
- 26378 - Iris: LTS0255186
- 82213 - Iris pseudacorus: 10.1016/0031-9422(91)84117-B
- 82213 - Iris pseudacorus: LTS0255186
- 267503 - Kochia: LTS0255186
- 4447 - Liliopsida: LTS0255186
- 3398 - Magnoliopsida: LTS0255186
- 553494 - Monopteryx: LTS0255186
- 997823 - Monopteryx inpae: 10.1016/0031-9422(81)85097-2
- 997823 - Monopteryx inpae: LTS0255186
- 40336 - Mucuna: LTS0255186
- 188013 - Rosulabryum: LTS0255186
- 99387 - Rosulabryum capillare:
- 99387 - Rosulabryum capillare: 10.1016/S0031-9422(00)82611-4
- 99387 - Rosulabryum capillare: 10.1515/ZNC-1985-7-802
- 3896 - Sophora: LTS0255186
- 48122 - Sophora secundiflora: 10.1016/0031-9422(95)93530-S
- 48122 - Sophora secundiflora: 10.1016/S0031-9422(96)00582-1
- 48122 - Sophora secundiflora: 10.1055/S-0029-1185944
- 48122 - Sophora secundiflora: LTS0255186
- 35493 - Streptophyta: LTS0255186
- 137301 - Styphnolobium: LTS0255186
- 3897 - Styphnolobium japonicum:
- 3897 - Styphnolobium japonicum: 10.1055/S-0029-1185944
- 3897 - Styphnolobium japonicum: LTS0255186
- 58023 - Tracheophyta: LTS0255186
- 3898 - Trifolium: LTS0255186
- 57577 - Trifolium pratense:
- 57577 - Trifolium pratense: 10.1016/S0003-2670(01)01370-8
- 57577 - Trifolium pratense: 10.1016/S0021-9673(96)00578-X
- 57577 - Trifolium pratense: 10.1021/JF991002+
- 57577 - Trifolium pratense: LTS0255186
- 33090 - Viridiplantae: LTS0255186
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ran Wen, Haining Lv, Yong Jiang, Pengfei Tu. Anti-inflammatory isoflavones and isoflavanones from the roots of Pongamia pinnata (L.) Pierre.
Bioorganic & medicinal chemistry letters.
2018 04; 28(6):1050-1055. doi:
10.1016/j.bmcl.2018.02.026. [PMID: 29482940] - Yan Song, Lan Pan, Wenjie Li, Yingying Si, Di Zhou, Chengjian Zheng, Xiaofang Hao, Xinyue Jia, Yuemei Jia, Minghui Shi, Xiaoguang Jia, Ning Li, Yue Hou. Natural neuro-inflammatory inhibitors from Caragana turfanensis.
Bioorganic & medicinal chemistry letters.
2017 10; 27(20):4765-4769. doi:
10.1016/j.bmcl.2017.08.047. [PMID: 28911817] - Wei Zhang, Xiao-Xia Zhang, Chang-Fa Liu, Rui-Li Song, Jing-Jing Wang. [Study on chemical constituents of Kochia scoparia].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2013 Jun; 36(6):921-4. doi:
. [PMID: 24380276] - Md Tariqul Islam Shajib, Hans Albert Pedersen, Anne Garfield Mortensen, Per Kudsk, Inge S Fomsgaard. Phytotoxic effect, uptake, and transformation of biochanin A in selected weed species.
Journal of agricultural and food chemistry.
2012 Oct; 60(43):10715-22. doi:
10.1021/jf3023589. [PMID: 23030687] - Preety Dixit, Raju Chillara, Vikram Khedgikar, Jyoti Gautam, Priyanka Kushwaha, Avinash Kumar, Divya Singh, Ritu Trivedi, Rakesh Maurya. Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity.
Bioorganic & medicinal chemistry letters.
2012 Jan; 22(2):890-7. doi:
10.1016/j.bmcl.2011.12.036. [PMID: 22212722] - Quan Cheng Chen, Wei Yun Zhang, Wenyi Jin, Ik Soo Lee, Byung-Sun Min, Hyun-Ju Jung, Minkyun Na, Sangmyung Lee, Kihwan Bae. Flavonoids and isoflavonoids from Sophorae Flos improve glucose uptake in vitro.
Planta medica.
2010 Jan; 76(1):79-81. doi:
10.1055/s-0029-1185944. [PMID: 19637114] - Kaoru Umehara, Kiyomitsu Nemoto, Ayako Matsushita, Eri Terada, Orawan Monthakantirat, Wanchai De-Eknamkul, Toshio Miyase, Tsutomu Warashina, Masakuni Degawa, Hiroshi Noguchi. Flavonoids from the heartwood of the Thai medicinal plant Dalbergia parviflora and their effects on estrogenic-responsive human breast cancer cells.
Journal of natural products.
2009 Dec; 72(12):2163-8. doi:
10.1021/np900676y. [PMID: 19928832] - Han-Qing Chen, Xi-Jin Wang, Zheng-Yu Jin, Xue-Ming Xu, Jian-Wei Zhao, Zheng-Jun Xie. Protective effect of isoflavones from Trifolium pratense on dopaminergic neurons.
Neuroscience research.
2008 Oct; 62(2):123-30. doi:
10.1016/j.neures.2008.07.001. [PMID: 18675857] - Jie Gao, Yanni Xu, Yuan Yang, Yi Yang, Zhihui Zheng, Wei Jiang, Bin Hong, Xuguang Yan, Shuyi Si. Identification of upregulators of human ATP-binding cassette transporter A1 via high-throughput screening of a synthetic and natural compound library.
Journal of biomolecular screening.
2008 Aug; 13(7):648-56. doi:
10.1177/1087057108320545. [PMID: 18594022] - José Gustavo L de Almeida, Edilberto R Silveira, Otília Deusdênia L Pessoa. NMR spectral assignments of a new [C--O--C] isoflavone dimer from Andira surinamensis.
Magnetic resonance in chemistry : MRC.
2008 Jan; 46(1):103-6. doi:
10.1002/mrc.2138. [PMID: 18098226] - Suresh Awale, Feng Li, Hiroko Onozuka, Hiroyasu Esumi, Yasuhiro Tezuka, Shigetoshi Kadota. Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition.
Bioorganic & medicinal chemistry.
2008 Jan; 16(1):181-9. doi:
10.1016/j.bmc.2007.10.004. [PMID: 17950610] - Rong Tsao, Yousef Papadopoulos, Raymond Yang, J Chris Young, Ken McRae. Isoflavone profiles of red clovers and their distribution in different parts harvested at different growing stages.
Journal of agricultural and food chemistry.
2006 Aug; 54(16):5797-805. doi:
10.1021/jf0614589. [PMID: 16881680] - Xingang Du, Yanjing Bai, Hong Liang, Zhiying Wang, Yuying Zhao, Qingying Zhang, Luqi Huang. Solvent effect in 1H NMR spectra of 3'-hydroxy-4'-methoxy isoflavonoids from Astragalus membranaceus var. mongholicus.
Magnetic resonance in chemistry : MRC.
2006 Jul; 44(7):708-12. doi:
10.1002/mrc.1806. [PMID: 16602082] - Qingli Wu, Mingfu Wang, James E Simon. Determination of isoflavones in red clover and related species by high-performance liquid chromatography combined with ultraviolet and mass spectrometric detection.
Journal of chromatography. A.
2003 Oct; 1016(2):195-209. doi:
10.1016/j.chroma.2003.08.001. [PMID: 14601839]
