Lupeyl acetate (BioDeep_00000000689)
Secondary id: BioDeep_00000264679, BioDeep_00000871839
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C32H52O2 (468.3967)
中文名称: 羽扇豆醇乙酸酯, 乙酸羽扇醇酯
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 62.9%
分子结构信息
SMILES: C=C(C)C1CCC2(C)CCC3(C)C(CCC4C5(C)CCC(OC(C)=O)C(C)(C)C5CCC43C)C12
InChI: InChI=1S/C32H52O2/c1-20(2)22-12-15-29(6)18-19-31(8)23(27(22)29)10-11-25-30(7)16-14-26(34-21(3)33)28(4,5)24(30)13-17-32(25,31)9/h22-27H,1,10-19H2,2-9H3
描述信息
Lupeol acetate is an organic molecular entity. It has a role as a metabolite.
Lupeol acetate is a natural product found in Euphorbia dracunculoides, Euphorbia larica, and other organisms with data available.
Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].
Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].
同义名列表
20 个代谢物同义名
[(1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-1-isopropenyl-3a,5a,5b,8,8,11a-hexamethyl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-yl] acetate; Acetic acid (1R,3aR,4S,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-1-isopropenyl-3a,5a,5b,8,8,11a-hexamethyl-eicosahydro-cyclopenta[a]chrysen-9-yl ester; Lup-20(29)-en-3-ol, acetate, (3.beta.)-; Lup-20(29)-en-3-ol, acetate, (3beta)-; LUP-20(30)-EN-3.BETA.-OL, ACETATE; Lup-20(29)-en-3.beta.-ol, acetate; LUP-20(29)-EN-3.BETA.-YL ACETATE; Lup-20(29)-en-3beta-ol, acetate; 3-acetyllupeol, (3alpha)-isomer; 3.BETA.-OAC-20(29)-LUPENE; LUPEOL ACETATE [MI]; 3-O-Acetyllupeol; CLERODOL ACETATE; LUPENYL ACETATE; UNII-WJ3A89G0H6; Lupeyl acetate; Lupeol acetate; 3-acetyllupeol; WJ3A89G0H6; Lupeol acetate
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:69744
- KEGG: C08630
- PubChem: 92157
- PubChem: 323074
- Metlin: METLIN41272
- ChEMBL: CHEMBL453802
- LipidMAPS: LMPR0106130002
- MeSH: 3-acetyllupeol
- ChemIDplus: 0001617681
- CAS: 1617-68-1
- medchemexpress: HY-126114
- PMhub: MS000020067
- MetaboLights: MTBLC69744
- PubChem: 10823
- KNApSAcK: C00003750
- 3DMET: B02283
- NIKKAJI: J145.292D
- KNApSAcK: 69744
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
182 个相关的物种来源信息
- 217838 - Acmella radicans: 10.1016/S0031-9422(00)84123-0
- 711014 - Acourtia nana: 10.1016/0031-9422(91)85125-J
- 387511 - Adenia hastata: 10.1055/S-2006-957747
- 82280 - Adenophora wawreana: 10.4268/CJCMM20111611
- 84857 - Alstonia boonei: 10.1002/PTR.2650070227
- 324585 - Ancathia igniaria: 10.1007/BF00598704
- 2775048 - Archidasyphyllum diacanthoides: 10.1016/S0031-9422(00)98112-3
- 378681 - Arctotis arctotoides: 10.1055/S-2007-969186
- 259893 - Artemisia argyi: 10.1248/CPB.32.723
- 194251 - Artocarpus altilis: 10.1016/0031-9422(91)83081-U
- 709040 - Artocarpus chama: 10.1016/S0031-9422(00)84340-X
- 2290778 - Artocarpus nobilis: 10.1016/J.PHYTOL.2010.07.008
- 1745002 - Austrobrickellia patens: 10.1016/S0031-9422(00)81176-0
- 759864 - Baccharoides anthelmintica: 10.1016/0031-9422(92)83142-L
- 29813 - Balanophora fungosa: 10.1248/CPB.57.1352
- 447008 - Balanophora harlandii: 10.1007/S10600-018-2437-5
- 1128101 - Balanophora indica:
- 1745017 - Bejaranoa balansae: 10.1016/0031-9422(95)00806-3
- 1745020 - Bishopiella elegans: 10.1016/0031-9422(91)83025-G
- 1205696 - Blainvillea acmella: 10.1016/S0031-9422(00)83115-5
- 130239 - Brachylaena discolor: 10.1016/S0031-9422(00)83886-8
- 1237404 - Brachylaena discolor var. rotundata: 10.1016/0031-9422(82)83157-9
- 493952 - Brachylaena huillensis: 10.1016/0031-9422(91)80119-L
- 2840031 - Brachylaena perrieri: 10.1016/0031-9422(91)80119-L
- 1542379 - Brachylaena ramiflora: 10.1021/NP0201220
- 714454 - Buddleja officinalis: 10.4268/CJCMM20110820
- 53846 - Caesalpinia pulcherrima: 10.1021/NP0201523
- 1125166 - Calea jamaicensis: 10.1016/S0031-9422(00)97995-0
- 41496 - Calendula officinalis: 10.1002/PCA.582
- 1548555 - Calostephane divaricata: 10.1016/S0031-9422(00)97762-8
- 1745026 - Campuloclinium megacephalum: 10.1016/0031-9422(91)83025-G
- 1928667 - Centaurea procurrens: 10.21608/RPBS.2018.5923
- 2072395 - Centaurea scoparia: 10.1007/S10600-007-0232-9
- 397370 - Centipeda minima: 10.1076/PHBI.37.4.314.5797
- 434639 - Chresta sphaerocephala: 10.1016/S0031-9422(82)85038-3
- 171767 - Chuquiraga ulicina:
- 143190 - Cirsium palustre: 10.1007/S10600-011-0023-1
- 2358360 - Cnidoscolus elasticus: 10.1021/NP50035A011
- 2358357 - Cnidoscolus multilobus: 10.4067/S0717-97072005000300011
- 2907091 - Cnidoscolus texanus: 10.1055/S-2007-990226
- 316878 - Cnidoscolus urens:
- 2358363 - Cnidoscolus vitifolius: 10.1016/S0031-9422(98)00069-7
- 91242 - Conyza bonariensis: 10.3390/50300571
- 2321275 - Coussarea paniculata: 10.1021/NP0204848
- 125682 - Cratystylis conocephala: 10.1016/0031-9422(88)84108-6
- 52844 - Cryptolepis nigrescens: 10.4268/CJCMM20150419
- 211151 - Cyanthillium cinereum: 10.1080/14786410500045598
- 434645 - Cyanthillium patulum: 10.1016/S0031-9422(00)84169-2
- 157702 - Cynara cornigera: 10.1016/0305-1978(88)90009-9
- 935151 - Cynara sibthorpiana: 10.1016/0305-1978(88)90009-9
- 1548336 - Cyrtocymura scorpioides:
- 2918710 - Daphne aurantiaca: 10.1021/NP9005053
- 13481 - Dasyphyllum diacanthoides: 10.1016/S0031-9422(00)98112-3
- 160049 - Dendrophthoe falcata: 10.1248/CPB.54.740
- 1184223 - Dicoma anomala: 10.1016/0031-9422(90)89034-7
- 984796 - Dorstenia brasiliensis: 10.1590/S0103-50531997000500016
- 1142948 - Dracaena cinnabari: 10.1016/0031-9422(94)00743-D
- 909143 - Echinops echinatus: 10.1016/J.BSE.2012.10.013
- 212299 - Elateriospermum tapos: 10.1021/NP070629G
- 318057 - Elephantopus mollis:
- 1569394 - Eremanthus capitatus: 10.1016/0031-9422(81)85163-1
- 1569396 - Eremanthus crotonoides: 10.1016/S0031-9422(82)85038-3
- 1548342 - Eremanthus glomerulatus:
- 1569399 - Eremanthus incanus: 10.1016/S0031-9422(00)83940-0
- 1569402 - Eremanthus mollis: 10.1016/S0031-9422(00)98542-X
- 1977555 - Erythrina sigmoidea: 10.1080/10286020.2010.546352
- 434659 - Ethulia conyzoides: 10.1016/0031-9422(80)83031-7
- 1333888 - Euphorbia altotibetica: 10.1002/CHIN.200345199
- 154986 - Euphorbia aphylla: 10.1515/ZNC-1988-1-206
- 3991 - Euphorbia characias: 10.1515/ZNC-1988-11-1202
- 1008446 - Euphorbia dracunculoides: 10.4268/CJCMM20142015
- 3993 - Euphorbia esula: 10.1016/S0031-9422(00)82608-4
- 1046465 - Euphorbia granulata: 10.4268/CJCMM20141227
- 1031526 - Euphorbia larica:
- 154997 - Euphorbia stygiana: 10.1016/S0031-9422(03)00007-4
- 13523 - Euptelea polyandra: 10.1021/NP50054A031
- 291470 - Fagonia mollis: 10.21608/BFSA.1999.66080
- 3494 - Ficus carica:
- 309266 - Ficus cordata: 10.1515/ZNB-2008-1113
- 182117 - Ficus macrophylla: 10.1071/CH9650226
- 309328 - Ficus mucuso: 10.1021/NP100896W
- 66386 - Ficus pumila: 10.1248/CPB.46.1408
- 176535 - Florestina tripteris: 10.1016/0031-9422(88)83154-6
- 1548571 - Geigeria brevifolia: 10.1016/S0031-9422(82)85040-1
- 268092 - Gelasia cretica: 10.1021/NP0103665
- 871893 - Gelasia tomentosa: 10.1080/10575639208048902
- 191881 - Guilandina bonduc:
- 2780416 - Gymnanthemum coloratum: 10.1016/0031-9422(91)83457-V
- 2676169 - Gymnanthemum myrianthum: 10.1016/0031-9422(82)85189-3
- 540063 - Gypothamnium pinifolium: 10.1016/0031-9422(88)80695-2
- 454511 - Haloxylon salicornicum: 10.1016/J.BMCL.2010.05.061
- 378691 - Haplocarpha lyrata: 10.1016/S0031-9422(00)82439-5
- 185653 - Heliopsis longipes: 10.1016/J.PHYTOL.2011.04.014
- 63476 - Hemidesmus indicus: 10.1016/S0031-9422(00)97582-4
- 434666 - Hilliardiella aristata:
- 1937595 - Himatanthus articulatus:
- 1552227 - Hymenopappus tenuifolius: 10.1016/0031-9422(88)80612-5
- 318058 - Ixeris chinensis:
- 1519174 - Ixeris japonica: 10.1248/YAKUSHI1947.103.3_356
- 75953 - Lactuca indica: 10.1248/CPB.59.767
- 4236 - Lactuca sativa: 10.1016/0031-9422(86)88039-6
- 2067305 - Lepidaploa leptoclada: 10.1135/CCCC19940913
- 2067288 - Lessingianthus mollissimus: 10.1021/NP50044A031
- 516727 - Leucheria gayana: 10.1016/0031-9422(91)85274-4
- 1911711 - Leucheria lithospermifolia: 10.1016/0031-9422(91)85274-4
- 460328 - Leucheria rosea: 10.1016/0031-9422(91)85274-4
- 55740 - Liabum solidagineum: 10.1016/S0031-9422(00)83499-8
- 983222 - Liatris laevigata: 10.1016/S0031-9422(00)86968-X
- 983224 - Liatris microcephala: 10.1016/S0031-9422(00)84035-2
- 344079 - Litsea sericea: 10.1016/0031-9422(92)83139-P
- 1548356 - Lychnophora candelabrum: 10.1016/0305-1978(91)90062-5
- 375932 - Lychnophora salicifolia: 10.1016/S0031-9422(00)82422-X
- 3496 - Maclura pomifera: 10.1007/BF02859211
- 149445 - Madia sativa: 10.1016/S0031-9422(00)82425-5
- 2771398 - Maquira coriacea: 10.1016/S0367-326X(01)00317-3
- 204129 - Mesosphaerum suaveolens: 10.3923/IJP.2008.227.229
- 1127088 - Mikania hookeriana: 10.1016/S0305-1978(03)00061-9
- 233715 - Mimusops elengi: 10.1016/S0031-9422(00)90897-5
- 516729 - Mutisia decurrens: 10.1016/0031-9422(91)85274-4
- 496639 - Mutisia retrorsa: 10.1016/S0031-9422(00)85512-0
- 2576591 - Nahuatlea hypoleuca: 10.1016/S0031-9422(00)81575-7
- 128655 - Neolitsea sericea: 10.1016/0031-9422(92)83139-P
- 1548360 - Orthopappus angustifolius: 10.1016/S0031-9422(00)81836-1
- 130290 - Pachylaena atriplicifolia: 10.1016/S0031-9422(00)90867-7
- 1569432 - Paralychnophora bicolor: 10.1016/S0031-9422(00)83940-0
- 463613 - Paranephelius uniflorus: 10.1016/S0031-9422(00)84042-X
- 1548621 - Pegolettia retrofracta: 10.1016/S0031-9422(00)97892-0
- 63483 - Pergularia daemia: 10.1002/JPS.3030360808
- 42345 - Phoenix dactylifera: 10.1016/0031-9422(83)80054-5
- 446128 - Phoenix theophrasti: 10.1016/0031-9422(83)80054-5
- 296035 - Phyllanthus urinaria: 10.1055/S-2006-958083
- 1885128 - Picris cyanocarpa: 10.1055/S-2006-962463
- 212690 - Picris hieracioides: 10.1248/CPB.43.1634
- 1548366 - Piptolepis ericoides: 10.1016/0031-9422(81)85163-1
- 1745127 - Planaltoa lychnophoroides: 10.1016/S0031-9422(00)95294-4
- 33090 - Plants: -
- 130299 - Plazia daphnoides: 10.1016/0031-9422(88)80695-2
- 1184246 - Pleiotaxis rugosa: 10.1016/0031-9422(82)80158-1
- 1548623 - Pluchea arguta: 10.1016/0031-9422(86)80034-6
- 76149 - Plumbago zeylanica: 10.1016/J.FITOTE.2004.03.009
- 52847 - Plumeria: 10.1201/9780203022320.CH4
- 62097 - Plumeria rubra: 10.1055/S-0029-1240611
- 397169 - Pouteria torta: 10.1590/S0102-695X2005000300002
- 1227256 - Proteopsis argentea: 10.1016/0031-9422(81)85165-5
- 169141 - Pseudocyphellaria aurata: 10.1071/CH9900623
- 999612 - Psorospermum androsaemifolium: 10.1002/CJOC.201190065
- 119188 - Pulicaria incisa: 10.1055/S-0034-1382449
- 53728 - Ratibida columnifera: 10.1016/S0031-9422(00)81502-2
- 43208 - Reichardia tingitana: 10.1016/0031-9422(91)80045-3
- 1548370 - Rolandra fruticosa: 10.1016/S0031-9422(00)97890-7
- 1933716 - Salvia cyanescens: 10.1016/S0031-9422(97)00146-5
- 57203 - Sambucus adnata: 10.1248/CPB.59.1396
- 4202 - Sambucus nigra: 10.1055/S-0028-1097541
- 886941 - Saussurea candicans: 10.1016/0031-9422(88)80305-4
- 405109 - Senecio crassissimus: 10.1016/S0031-9422(00)84168-0
- 407078 - Sideroxylon rotundifolium: 10.1055/S-0028-1097766
- 59297 - Solidago canadensis: 10.1016/J.BMC.2004.08.048
- 50193 - Sonchus asper: 10.1135/CCCC19793391
- 1136794 - Spiracantha cornifolia: 10.1016/0031-9422(90)87130-M
- 413302 - Streptocaulon juventas: 10.1016/J.FITOTE.2004.06.007
- 3743 - Synsepalum dulcificum: 10.1007/S10600-010-9658-6
- 403124 - Tabernaemontana catharinensis: 10.1016/S0021-9673(98)00084-3
- 52861 - Tabernaemontana divaricata: 10.1021/NP50057A012
- 761072 - Tabernaemontana heterophylla: 10.1590/1809-43921983132409
- 761076 - Tabernaemontana laeta: 10.1590/S0103-50532001000300008
- 761084 - Tabernaemontana odoratissima: 10.1016/S0031-9422(00)90127-4
- 403125 - Tabernaemontana pachysiphon: 10.1016/S0031-9422(00)83488-3
- 761103 - Tabernaemontana ventricosa: 10.1021/NP50046A049
- 506632 - Tamaulipa azurea: 10.1016/0031-9422(91)83025-G
- 2803980 - Taraxacum hallaisanense: 10.1007/BF02986020
- 131536 - Taraxacum japonicum: 10.1248/BPB.22.606
- 170727 - Taraxacum platycarpum: 10.1248/CPB.60.205
- 434697 - Tarlmounia elliptica: 10.1016/0031-9422(82)80164-7
- 52862 - Thevetia peruviana:
- 460359 - Urmenetea atacamensis: 10.1016/0031-9422(88)80708-8
- 1620208 - Verbesina virginica: 10.1016/S0031-9422(00)91034-3
- 2067322 - Vernonanthura fagifolia: 10.1016/S0031-9422(00)84169-2
- 1508306 - Vernonanthura phosphorica: 10.1016/S0031-9422(00)84169-2
- 992807 - Vernonia colorata: 10.1016/0031-9422(91)83457-V
- 1224204 - Vernonia elaeagnifolia: 10.1016/0031-9422(82)80164-7
- 85297 - Xerosicyos danguyi: 10.1016/S0305-1978(98)00070-2
- 159071 - Zanthoxylum ailanthoides:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Qun Shi, Yi-Wei Sun, Dali Meng. Phytochemical and cytotoxic studies on the roots of Euphorbia fischeriana.
Bioorganic & medicinal chemistry letters.
2017 01; 27(2):266-270. doi:
10.1016/j.bmcl.2016.11.063
. [PMID: 27913179] - Patrícia de Brum Vieira, Nícolas Luiz Feijó Silva, Gloria Narjara Santos da Silva, Denise Brentan Silva, Norberto Peporine Lopes, Simone Cristina Baggio Gnoatto, Márcia Vanusa da Silva, Alexandre José Macedo, Jaume Bastida, Tiana Tasca. Caatinga plants: Natural and semi-synthetic compounds potentially active against Trichomonas vaginalis.
Bioorganic & medicinal chemistry letters.
2016 May; 26(9):2229-36. doi:
10.1016/j.bmcl.2016.03.061
. [PMID: 27020521] - Nesrin M Fayek, Azza R Abdel Monem, Mohamed Y Mossa, Meselhy R Meselhy, Amani H Shazly. Chemical and biological study of Manilkara zapota (L.) Van Royen leaves (Sapotaceae) cultivated in Egypt.
Pharmacognosy research.
2012 Apr; 4(2):85-91. doi:
10.4103/0974-8490.94723
. [PMID: 22518080] - Taha S El-Alfy, Shahira M Ezzat, Ahmed K Hegazy, Aziza M M Amer, Gehan M Kamel. Isolation of biologically active constituents from Moringa peregrina (Forssk.) Fiori. (family: Moringaceae) growing in Egypt.
Pharmacognosy magazine.
2011 Apr; 7(26):109-15. doi:
10.4103/0973-1296.80667
. [PMID: 21716619] - Rajnish Gupta, Jai B S Kachhawa, R S Gupta, Anil Kumar Sharma, M C Sharma, M P Dobhal. Phytochemical evaluation and antispermatogenic activity of Thevetia peruviana methanol extract in male albino rats.
Human fertility (Cambridge, England).
2011 Mar; 14(1):53-9. doi:
10.3109/14647273.2010.542230
. [PMID: 21466267] - Mohammad Ali, Nisha Chaudhary. Ficus hispida Linn.: A review of its pharmacognostic and ethnomedicinal properties.
Pharmacognosy reviews.
2011 Jan; 5(9):96-102. doi:
10.4103/0973-7847.79104
. [PMID: 22096323] - Daniel L Lucetti, Elaine Cp Lucetti, Mary Anne M Bandeira, Helenicy Nh Veras, Aline H Silva, Luzia Kalyne Am Leal, Amanda A Lopes, Victor Cc Alves, Gabriela S Silva, Gerly Anne Brito, Glauce B Viana. Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) Plumel.
Journal of inflammation (London, England).
2010 Dec; 7(?):60. doi:
10.1186/1476-9255-7-60
. [PMID: 21167055] - Jean Jules Kezetas Bankeu, Sufyan Awad Alkarim Mustafa, Anar Sahib Gojayev, Bruno Djakou Lenta, Didérot Tchamo Noungoué, Silvère Augustin Ngouela, Khalid Asaad, Mohammed Iqbal Choudhary, Sean Prigge, Akif Alekper Guliyev, Augustin Ephrem Nkengfack, Etienne Tsamo, Muhammad Shaiq Ali. Ceramide and Cerebroside from the stem bark of Ficus mucuso (Moraceae).
Chemical & pharmaceutical bulletin.
2010 Dec; 58(12):1661-5. doi:
10.1248/cpb.58.1661
. [PMID: 21139276] - Joseph J Magadula. A bioactive isoprenylated xanthone and other constituents of Garcinia edulis.
Fitoterapia.
2010 Jul; 81(5):420-3. doi:
10.1016/j.fitote.2009.12.002
. [PMID: 20006684] - Yan-Wen Li, Zhi-Rong Sun, Zhi-Yong Li, Jia-Xing Jin, Wen-Quan Wang, Yu-Ning Yan. [Studies on the chemical constituents of Ficus microcarpa].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2010 Jun; 33(6):918-20. doi:
. [PMID: 21049616]
- Cr Pawar, Sj Surana. Antioxidant Properties of the Methanol Extract of the Wood and Pericarp of Caesalpinia decapetala.
Journal of young pharmacists : JYP.
2010 Jan; 2(1):45-9. doi:
10.4103/0975-1483.62212
. [PMID: 21331190] - Mitja Martelanc, Irena Vovk, Breda Simonovska. Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography.
Journal of chromatography. A.
2009 Sep; 1216(38):6662-70. doi:
10.1016/j.chroma.2009.07.038
. [PMID: 19695573] - Manish A Rachchh, Sunita M Jain. Gastroprotective effect of Benincasa hispida fruit extract.
Indian journal of pharmacology.
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