Astaxanthin (BioDeep_00000000579)

 

Secondary id: BioDeep_00000267425

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


3,3-Dihydroxy-beta,beta-carotene-4,4-dione;(S)-6-hydroxy-3-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-((S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohex-1-enyl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl)-2,4,4-trimethylcyclohex-2-enone;

化学式: C40H52O4 (596.3865392)
中文名称: 虾青素
谱图信息: 最多检出来源 Homo sapiens(blood) 1.42%

Reviewed

Last reviewed on 2024-07-24.

Cite this Page

Astaxanthin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/astaxanthin (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000000579). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C/C(=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C(=O)C(CC1(C)C)O)/C=C/C=C(\C)/C=C/C1=C(C)C(=O)C(CC1(C)C)O
InChI: InChI=1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,35-36,41-42H,25-26H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,27-15-,28-16+,29-19+,30-20+

描述信息

Astaxanthin (pronounced as-tuh-zan-thin) is a carotenoid. It belongs to a larger class of phytochemicals known as terpenes. It is classified as a xanthophyll, which means "yellow leaves". Like many carotenoids, it is a colorful, lipid-soluble pigment. Astaxanthin is produced by microalgae, yeast, salmon, trout, krill, shrimp, crayfish, crustaceans, and the feathers of some birds. Professor Basil Weedon was the first to map the structure of astaxanthin.; Astaxanthin is the main carotenoid pigment found in aquatic animals. It is also found in some birds, such as flamingoes, quails, and other species. This carotenoid is included in many well-known seafoods such as salmon, trout, red seabream, shrimp, lobster, and fish eggs. Astaxanthin, similar to other carotenoids, cannot be synthesized by animals and must be provided in the diet. Mammals, including humans, lack the ability to synthesize astaxanthin or to convert dietary astaxanthin into vitamin A. Astaxanthin belongs to the xanthophyll class of carotenoids. It is closely related to beta-carotene, lutein, and zeaxanthin, sharing with them many of the general metabolic and physiological functions attributed to carotenoids. In addition, astaxanthin has unique chemical properties based on its molecular structure. The presence of the hydroxyl (OH) and keto (CdO) moieties on each ionone ring explains some of its unique features, namely, the ability to be esterified and a higher antioxidant activity and a more polar nature than other carotenoids. In its free form, astaxanthin is considerably unstable and particularly susceptible to oxidation. Hence it is found in nature either conjugated with proteins (e.g., salmon muscle or lobster exoskeleton) or esterified with one or two fatty acids (monoester and diester forms), which stabilize the molecule. Various astaxanthin isomers have been characterized on the basis of the configuration of the two hydroxyl groups on the molecule. the geometrical and optical isomers of astaxanthin are distributed selectively in different tissues and that levels of free astaxanthin in the liver are greater than the corresponding concentration in the plasma, suggesting concentrative uptake by the liver. Astaxanthin, similar to other carotenoids, is a very lipophilic compound and has a low oral bioavailability. This criterion has limited the ability to test this compound in well-defined rodent models of human disease. (PMID: 16562856); Astaxanthin is a carotenoid widely used in salmonid and crustacean aquaculture to provide the pink color characteristic of that species. This application has been well documented for over two decades and is currently the major market driver for the pigment. Additionally, astaxanthin also plays a key role as an intermediary in reproductive processes. Synthetic astaxanthin dominates the world market but recent interest in natural sources of the pigment has increased substantially. Common sources of natural astaxanthin are the green algae Haematococcus pluvialis, the red yeast, Phaffia rhodozyma, as well as crustacean byproducts. Astaxanthin possesses an unusual antioxidant activity which has caused a surge in the nutraceutical market for the encapsulated productand is) also, health benefits such as cardiovascular disease prevention, immune system boosting, bioactivity against Helycobacter pylori, and cataract prevention, have been associated with astaxanthin consumption. Research on the health benefits of astaxanthin is very recent and has mostly been performed in vitro or at the pre-clinical level with humans. (PMID: 16431409); Astaxanthin, unlike some carotenoids, does not convert to Vitamin A (retinol) in the human body. Too much Vitamin A is toxic for a human, but astaxanthin is not. However, it is a powerful antioxidant; it is claimed to be 10 times more capable than other carotenoids. However, other sources suggest astaxanthin has slightly lower antioxidant activity than other carotenoids.; While astaxanthin is a natural nutr...
Astaxanthin is the main carotenoid pigment found in aquatic animals. It is also found in some birds, such as flamingoes, quails, and other species. This carotenoid is included in many well-known seafoods such as salmon, trout, red seabream, shrimp, lobster, and fish eggs. Astaxanthin, similar to other carotenoids, cannot be synthesized by animals and must be provided in the diet. Mammals, including humans, lack the ability to synthesize astaxanthin or to convert dietary astaxanthin into vitamin A. Astaxanthin belongs to the xanthophyll class of carotenoids. It is closely related to beta-carotene, lutein, and zeaxanthin, sharing with them many of the general metabolic and physiological functions attributed to carotenoids. In addition, astaxanthin has unique chemical properties based on its molecular structure. The presence of the hydroxyl (OH) and keto (CdO) moieties on each ionone ring explains some of its unique features, namely, the ability to be esterified and a higher antioxidant activity and a more polar nature than other carotenoids. In its free form, astaxanthin is considerably unstable and particularly susceptible to oxidation. Hence it is found in nature either conjugated with proteins (e.g. salmon muscle or lobster exoskeleton) or esterified with one or two fatty acids (monoester and diester forms) which stabilize the molecule. Various astaxanthin isomers have been characterized on the basis of the configuration of the two hydroxyl groups on the molecule. The geometrical and optical isomers of astaxanthin are distributed selectively in different tissues and levels of free astaxanthin in the liver are greater than the corresponding concentration in the plasma, suggesting concentrative uptake by the liver. Astaxanthin, similar to other carotenoids, is a very lipophilic compound and has a low oral bioavailability. This criterion has limited the ability to test this compound in well-defined rodent models of human disease (PMID: 16562856). Astaxanthin is a carotenoid widely used in salmonid and crustacean aquaculture to provide the pink colour characteristic of that species. This application has been well documented for over two decades and is currently the major market driver for the pigment. Additionally, astaxanthin also plays a key role as an intermediary in reproductive processes. Synthetic astaxanthin dominates the world market but recent interest in natural sources of the pigment has increased substantially. Common sources of natural astaxanthin are the green algae Haematococcus pluvialis (the red yeast), Phaffia rhodozyma, as well as crustacean byproducts. Astaxanthin possesses an unusual antioxidant activity which has caused a surge in the nutraceutical market for the encapsulated product. Also, health benefits such as cardiovascular disease prevention, immune system boosting, bioactivity against Helicobacter pylori, and cataract prevention, have been associated with astaxanthin consumption. Research on the health benefits of astaxanthin is very recent and has mostly been performed in vitro or at the pre-clinical level with humans (PMID: 16431409). Astaxanthin is used in fish farming to induce trout flesh colouring.
Astaxanthin is a carotenone that consists of beta,beta-carotene-4,4-dione bearing two hydroxy substituents at positions 3 and 3 (the 3S,3S diastereomer). A carotenoid pigment found mainly in animals (crustaceans, echinoderms) but also occurring in plants. It can occur free (as a red pigment), as an ester, or as a blue, brown or green chromoprotein. It has a role as an anticoagulant, an antioxidant, a food colouring, a plant metabolite and an animal metabolite. It is a carotenone and a carotenol. It derives from a hydride of a beta-carotene.
Astaxanthin is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is found in the majority of aquatic organisms with red pigment. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may be found in fish feed or some animal food as a color additive.
Astaxanthin is a natural product found in Ascidia zara, Linckia laevigata, and other organisms with data available.
Astaxanthin is a natural and synthetic xanthophyll and nonprovitamin A carotenoid, with potential antioxidant, anti-inflammatory and antineoplastic activities. Upon administration, astaxanthin may act as an antioxidant and reduce oxidative stress, thereby preventing protein and lipid oxidation and DNA damage. By decreasing the production of reactive oxygen species (ROS) and free radicals, it may also prevent ROS-induced activation of nuclear factor-kappa B (NF-kB) transcription factor and the production of inflammatory cytokines such as interleukin-1beta (IL-1b), IL-6 and tumor necrosis factor-alpha (TNF-a). In addition, astaxanthin may inhibit cyclooxygenase-1 (COX-1) and nitric oxide (NO) activities, thereby reducing inflammation. Oxidative stress and inflammation play key roles in the pathogenesis of many diseases, including cardiovascular, neurological, autoimmune and neoplastic diseases.
A carotenone that consists of beta,beta-carotene-4,4-dione bearing two hydroxy substituents at positions 3 and 3 (the 3S,3S diastereomer). A carotenoid pigment found mainly in animals (crustaceans, echinoderms) but also occurring in plants. It can occur free (as a red pigment), as an ester, or as a blue, brown or green chromoprotein.
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
C308 - Immunotherapeutic Agent > C210 - Immunoadjuvant
C2140 - Adjuvant

同义名列表

68 个代谢物同义名

3,3-Dihydroxy-beta,beta-carotene-4,4-dione;(S)-6-hydroxy-3-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-((S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohex-1-enyl)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl)-2,4,4-trimethylcyclohex-2-enone;; (6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one; (6S)-6-Hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxo-1-cyclohexenyl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethyl-1-cyclohex-2-enone; (6S)-6-hydroxy-3-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethyl-3-oxocyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-2,4,4-trimethylcyclohex-2-en-1-one; (6S,6S)-3,3-((1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)bis(6-hydroxy-2,4,4-trimethylcyclohex-2-enone); .beta.,.beta.-Carotene-4,4-dione, 3,3-dihydroxy-, (3S,3S)-; 3,3-Dihydroxy-.beta.,.beta.-carotene-4,4-dione, (3S,3S)-; (3S,3S)-3,3-DIHYDROXY-.BETA.,.BETA.-CAROTENE-4,4-DIONE; 3-(4,6-Dimethyl-2-oxo-2H-pyrimidin-1-yl)-propionicacid; all-trans-3,3-dihydroxy-beta-Carotene-4,4-dione (8CI); .beta.-Carotene-4,4-dione, 3,3-dihydroxy-, all-trans-; 3,3-Dihydroxy-beta,beta-carotene-4,4-dione, (3S,3S)-; (3S,3S)-3,3-Dihydroxy-beta,beta-carotene-4,4-dione; all-trans-3,3-dihydroxy-b-Carotene-4,4-dione (8CI); (3S,3’S)-3,3’-dihydroxy-β,β-carotene-4,4’-dione; (3S,3s)-3,3-Dihydroxy-b,b-carotene-4,4-dione; (3S,3s)-3,3-Dihydroxy-β,β-carotene-4,4-dione; 3,3-dihydroxy-4,4-diketo-beta,beta-carotene; 3,3-Dihydroxy-beta,beta-carotene-4,4-dione; all-trans-Astaxanthin, analytical standard; 3,3-DIHYDROXY-4,4-DIKETO-.BETA.-CAROTENE; 3,3-Dihydroxy-beta-carotene-4,4-dione; 3,3-Dihydroxy-b,b-carotene-4,4-dione; 3,3-Dihydroxy-β,β-carotene-4,4-dione; 3,3-Dihydroxy-β-carotene-4,4-dione; 3,3-Dihydroxy-b-carotene-4,4-dione; Astaxanthin, all-trans-, (3S,3S)-; (3S,3’S)-all-trans-astaxanthin; all-trans-(3S,3’S)-astaxanthin; (3S,3S)-all-trans-Astaxanthin; Algae Haematococcus pluvialis; all-trans-(3S,3S)-astaxanthin; Astaxanthin, >=98\\% (HPLC); Astaxanthin, 5\\% active; beta-Carotene-4,4-dione; Astaxanthin, all-trans-; Astaxanthin, (3S,3S)-; all-trans-Astaxanthin; b-Carotene-4,4-dione; ASTAXANTHIN [USP-RS]; (3S,3’S)-astaxanthin; ASTAXANTHIN [WHO-DD]; ASTAXANTHIN [MART.]; (3S,3S)-Astaxanthin; ASTAXANTHIN [VANDF]; ASTAXANTHIN [INCI]; ASTAXANTHIN [HSDB]; BioAstin oleoresin; 3S,3S-Astaxanthin; trans-Astaxanthin; (S,S)-Astaxanthin; Astaxanthin (6CI); ASTAXANTHIN [MI]; UNII-8XPW32PR7I; Carophyll Pink; Lucantin Pink; E-astaxanthin; astaxanthine; Astaxanthin; 8XPW32PR7I; astaxantin; AstaREAL; Ovoester; BioAstin; Natupink; AstaXin; e 161J; 3,3-dihydroxy-β,β-carotene-4,4-dione



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

4 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(4)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

101 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuxin Wang, Jia Wang, Shufang Yang, Qingping Liang, Ziqiang Gu, Ying Wang, Haijin Mou, Han Sun. Selecting a preculture strategy for improving biomass and astaxanthin productivity of Chromochloris zofingiensis. Applied microbiology and biotechnology. 2024 Dec; 108(1):117. doi: 10.1007/s00253-023-12873-x. [PMID: 38204137]
  • Xiang-Bo Zeng, Fa-Wen Yin, Guan-Hua Zhao, Chao Guo, De-Yang Li, Hui-Lin Liu, Lei Qin, Fereidoon Shahidi, Da-Yong Zhou. Mechanism of color change in Antarctic krill oil during storage. Food chemistry. 2024 Jun; 444(?):138583. doi: 10.1016/j.foodchem.2024.138583. [PMID: 38309082]
  • Hao-Hong Chen, Jing-Xuan Wu, Rui Huang, Jv-Liang Dai, Ming-Hua Liang, Jian-Guo Jiang. Enhancing astaxanthin accumulation through the expression of the plant-derived astaxanthin biosynthetic pathway in Dunaliella salina. Plant physiology and biochemistry : PPB. 2024 Jun; 211(?):108697. doi: 10.1016/j.plaphy.2024.108697. [PMID: 38705045]
  • Shujie Wang, Yuyue Qin, Yaping Liu, Guoqin Liu, Guiguang Cheng, Thanapop Soteyome. Controlling release of astaxanthin in β-sitosterol oleogel-based emulsions via different self-assembled mechanisms and composition of the oleogelators. Food research international (Ottawa, Ont.). 2024 Jun; 186(?):114350. doi: 10.1016/j.foodres.2024.114350. [PMID: 38729698]
  • Mingyuan Huang, Yujuan Xu, Lina Xu, Xing Chen, Mengzhen Ding, Yun Bai, Xinglian Xu, Xianming Zeng. The evaluation of mixed-layer emulsions stabilized by myofibrillar protein-chitosan complex for delivering astaxanthin: Fabrication, characterization, stability and in vitro digestibility. Food chemistry. 2024 May; 440(?):138204. doi: 10.1016/j.foodchem.2023.138204. [PMID: 38134832]
  • Yan Bai, Yilin Lu, Peng Yang, Yicheng Ding, Yadan Zheng, Zhigang Ke, Shulai Liu, Yuting Ding, Xuxia Zhou. Simultaneous determination of multiple quality indices of dried shrimp (Parapenaeopsis hardwickii) during storage using Raman spectroscopy. Journal of the science of food and agriculture. 2024 May; 104(7):4226-4233. doi: 10.1002/jsfa.13304. [PMID: 38299755]
  • Suleiman Fatimoh Ozavize, Cheng-Wei Qiu, Feibo Wu. Astaxanthin induces plant tolerance against cadmium by reducing cadmium uptake and enhancing carotenoid metabolism for antioxidant defense in wheat (Triticum aestivum L.). Plant physiology and biochemistry : PPB. 2024 May; 210(?):108622. doi: 10.1016/j.plaphy.2024.108622. [PMID: 38677187]
  • Cassamo U Mussagy, Ana C R V Dias, Valeria C Santos-Ebinuma, M Shaaban Sadek, Mushtaq Ahmad, Cleverton R de Andrade, Felipe F Haddad, Jean L Dos Santos, Cauê B Scarim, Jorge F B Pereira, Juliana Ferreira Floriano, Rondinelli D Herculano, Ahmad Mustafa. Is the carotenoid production from Phaffia rhodozyma yeast genuinely sustainable? a comprehensive analysis of biocompatibility, environmental assessment, and techno-economic constraints. Bioresource technology. 2024 Apr; 397(?):130456. doi: 10.1016/j.biortech.2024.130456. [PMID: 38369081]
  • Qizhao Li, Mutian Jia, Hui Song, Jun Peng, Wei Zhao, Weifang Zhang. Astaxanthin Inhibits STING Carbonylation and Enhances Antiviral Responses. Journal of immunology (Baltimore, Md. : 1950). 2024 Apr; 212(7):1188-1195. doi: 10.4049/jimmunol.2300306. [PMID: 38391298]
  • Elif Erbaş, Hilal Üstündağ, Emre Öztürk, Seçil Nazife Parlak, Tuğçe Atcalı. Astaxanthin treatment reduces kidney damage and facilitates antioxidant recovery in lithium-intoxicated rats. Toxicon : official journal of the International Society on Toxinology. 2024 Apr; 241(?):107664. doi: 10.1016/j.toxicon.2024.107664. [PMID: 38460603]
  • Hamieh Goshtasbi, Elaheh Dalir Abdolahinia, Marziyeh Fathi, Ali Movafeghi, Hossein Omidian, Jaleh Barar, Yadollah Omidi. Astaxanthin-loaded alginate-chitosan gel beads activate Nrf2 and pro-apoptotic signalling pathways against oxidative stress. Journal of microencapsulation. 2024 Mar; 41(2):140-156. doi: 10.1080/02652048.2024.2319048. [PMID: 38410930]
  • Supisara Jitpasutham, Watcharin Sinsomsak, Piyanan Chuesiang, Victor Ryu, Ubonrat Siripatrawan. Green active coating from chitosan incorporated with spontaneous cinnamon oil nanoemulsion: Effects on dried shrimp quality and shelf life. International journal of biological macromolecules. 2024 Mar; 262(Pt 2):129711. doi: 10.1016/j.ijbiomac.2024.129711. [PMID: 38278379]
  • Peng-Yang Liu, Jun-Jie Wu, Gang Li, Chu-Bin Lin, Shan Jiang, Shuang Liu, Xia Wan. The Biosynthesis of Astaxanthin Esters in Schizochytrium sp. is Mediated by a Bifunctional Diacylglycerol Acyltransferase. Journal of agricultural and food chemistry. 2024 Feb; 72(7):3584-3595. doi: 10.1021/acs.jafc.3c09086. [PMID: 38344823]
  • Yihua Ma, Xin Sun, Youreng Sun, Haoyang Li, Hongwei Li, Xiangfei Jiao. Synchronous enhancement of astaxanthin and lipid accumulation in Haematococcus lacustris through co-mutation of ethanol and atmospheric and room temperature plasma: Exploration of characteristics and underlying mechanisms. Bioresource technology. 2024 Feb; 394(?):130305. doi: 10.1016/j.biortech.2024.130305. [PMID: 38199438]
  • Youwu Liao, Haiqiao Wang, Shuang Li, Yuanyuan Xue, Yunqiu Chen, Michael Adu-Frimpong, Ying Xu, Jiangnan Yu, Ximing Xu, Hugh D C Smyth, Yuan Zhu. Preparation of astaxanthin-loaded composite micelles with coaxial electrospray technology for enhanced oral bioavailability and improved antioxidation capability. Journal of the science of food and agriculture. 2024 Feb; 104(3):1408-1419. doi: 10.1002/jsfa.13019. [PMID: 37782057]
  • Grzegorz Dąbrowski, Sylwester Czaplicki, Marcin Szustak, Eliza Korkus, Edyta Gendaszewska-Darmach, Iwona Konopka. The impact of selected xanthophylls on oil hydrolysis by pancreatic lipase: in silico and in vitro studies. Scientific reports. 2024 02; 14(1):2731. doi: 10.1038/s41598-024-53312-9. [PMID: 38302772]
  • Adolf Acheampong, Rong Wang, Shereen M Elsherbiny, Precious Bondzie-Quaye, Qing Huang. Exogenous arginine promotes the coproduction of biomass and astaxanthin under high-light conditions in Haematococcus pluvialis. Bioresource technology. 2024 Feb; 393(?):130001. doi: 10.1016/j.biortech.2023.130001. [PMID: 37956949]
  • Joanna Tkaczewska, Piotr Kulawik, Ewelina Jamróz, Martina Čagalj, Roberta Frleta Matas, Vida Šimat. Valorisation of prawn/shrimp shell waste through the production of biologically active components for functional food purposes. Journal of the science of food and agriculture. 2024 Jan; 104(2):707-715. doi: 10.1002/jsfa.12969. [PMID: 37669418]
  • Alejandro Torres-Haro, Jorge Verdín, Manuel R Kirchmayr, Melchor Arellano-Plaza. Combined 6-benzylaminopurine and H2O2 stimulate the astaxanthin biosynthesis in Xanthophyllomyces dendrorhous. Applied microbiology and biotechnology. 2024 Jan; 108(1):158. doi: 10.1007/s00253-023-12875-9. [PMID: 38252271]
  • Ngoc-Bich-Dao Vu, Ngoc-Duy Pham, Thi-Ngoc-Mai Tran, Xuan-Hai Pham, Dai-Nghiep Ngo, Minh-Hiep Nguyen. Possibility of nanostructured lipid carriers encapsulating astaxanthin from Haematococcus pluvialis to alleviate skin injury in radiotherapy. International journal of radiation biology. 2024; 100(2):209-219. doi: 10.1080/09553002.2023.2267650. [PMID: 37819928]
  • Chong Liu, Hao-Yang Geng, Wang-Xi Li, Ya-Ying Li, Yu-Sheng Lu, Kai-Zhi Xie, Li Li Sun, Jie-Xin Zhang, Huan-Long Peng, Chao-Hong Shi, Wan-Ling Li, Chang-Min Zhou, Wen-Jie Gu, Dan Wang. Innate Root Exudates Contributed to Contrasting Coping Strategies in Response to Ralstonia solanacearum in Resistant and Susceptible Tomato Cultivars. Journal of agricultural and food chemistry. 2023 Dec; 71(50):20092-20104. doi: 10.1021/acs.jafc.3c06410. [PMID: 38051256]
  • Peng Wang, Xian Zheng, Ronghuan Du, Jinghan Xu, Jing Li, Huaqi Zhang, Xi Liang, Hui Liang. Astaxanthin Protects against Alcoholic Liver Injury via Regulating Mitochondrial Redox Balance and Calcium Homeostasis. Journal of agricultural and food chemistry. 2023 Dec; 71(49):19531-19550. doi: 10.1021/acs.jafc.3c05529. [PMID: 38038704]
  • Kristina Radić, Ana Isabel Barbosa, Salette Reis, Marijan Marijan, Sofia Antunes Costa Lima, Dubravka Vitali Čepo. Preparation of astaxanthin/zeaxanthin-loaded nanostructured lipid carriers for enhanced bioavailability: Characterization-, stability-and permeability study. Acta pharmaceutica (Zagreb, Croatia). 2023 Dec; 73(4):581-599. doi: 10.2478/acph-2023-0038. [PMID: 38147480]
  • Megha Bhat Agni, Pramukh Subrahmanya Hegde, Harshini Ullal, K M Damodara Gowda. Nutritional efficacy of Astaxanthin in modulating orexin peptides and fatty acid level during adult life of rats exposed to perinatal undernutrition stress. Nutritional neuroscience. 2023 Nov; 26(11):1045-1057. doi: 10.1080/1028415x.2022.2123184. [PMID: 36154638]
  • Vaibhav Sunil Tambat, Anil Kumar Patel, Reeta Rani Singhania, Akash Pralhad Vadrale, Archana Tiwari, Chiu-Wen Chen, Cheng-Di Dong. Sustainable mixotrophic microalgae refinery of astaxanthin and lipid from Chlorella zofingiensis. Bioresource technology. 2023 Nov; 387(?):129635. doi: 10.1016/j.biortech.2023.129635. [PMID: 37544537]
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