Lycopene (BioDeep_00000000571)

 

Secondary id: BioDeep_00000019043, BioDeep_00000409930

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


2,6,8,10,12,14,16,18,20,22,24,26,30-Dotriacontatridecaene, 2,6,10,14,19,23,27,31-octamethyl-, (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-

化学式: C40H56 (536.4382)
中文名称: 番茄红素, 茄红素, 西红柿红素
谱图信息: 最多检出来源 Homo sapiens(blood) 36.96%

分子结构信息

SMILES: C/C(/C)=C/CC/C(/C)=C/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C=C(\C)/CC/C=C(\C)/C
InChI: InChI=1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

描述信息

Lycopene is an acyclic carotene commonly obtained from tomatoes and other red fruits. It has a role as an antioxidant and a plant metabolite. It contains a carotenoid psi-end derivative.
Lycopene is a naturally occuring red carotenoid pigment that is responsible in red to pink colors seen in tomatoes, pink grapefruit, and other foods. Having a chemical formula of C40H56, lycopene is a tetraterpene assembled from eight isoprene units that are solely composed of carbon and hydrogen. Lycophene may undergo extensive isomerization that allows 1056 theoretical cis-trans configurations; however the all-trans configuration of lycopene is the most predominant isomer found in foods that gives the red hue. Lycopene is a non-essential human nutrient that is classified as a non-provitamin A carotenoid pigment since it lacks a terminal beta ionone ring and does not mediate vitamin A activity. However lycophene is a potent antioxidant molecule that scavenges reactive oxygen species (ROS) singlet oxygen. Tomato lycopene extract is used as a color additive in food products.
Lycopene is a natural product found in Rhodobacter capsulatus, Afifella marina, and other organisms with data available.
Lycopene is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids are pigment compounds found in photosynthetic organisms (plants, algae, and some types of fungus), and are chemically characterized by a large polyene chain containing 35-40 carbon atoms; some carotenoid polyene chains are terminated by two 6-carbon rings. In animals, carotenoids such as lycopene may possess antioxidant properties which may retard aging and many degenerative diseases. As an essential nutrient, lycopene is required in the animal diet. (NCI04)
A carotenoid and red pigment produced by tomatoes, other red fruits and vegetables, and photosynthetic algae. It is a key intermediate in the biosynthesis of other carotenoids, and has antioxidant, anti-carcinogenic, radioprotective, and anti-inflammatory properties.
Lycopene (molecular formula: C40H56) is a bright red carotenoid pigment. It is a phytochemical found in tomatoes and other red fruits. Lycopene is the most common carotenoid in the human body and is one of the most potent carotenoid antioxidants. Its name is derived from the tomatos species classification, Solanum lycopersicum. Lycopene is a terpene assembled from 8 isoprene units. Lycopene is the most powerful carotenoid quencher of singlet oxygen. Singlet oxygen from ultraviolet light is a primary cause of skin aging (Wikipedia).
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
An acyclic carotene commonly obtained from tomatoes and other red fruits.
D020011 - Protective Agents > D011837 - Radiation-Protective Agents
D020011 - Protective Agents > D016588 - Anticarcinogenic Agents
D000893 - Anti-Inflammatory Agents
D000970 - Antineoplastic Agents
It is used as food colouring

同义名列表

66 个代谢物同义名

2,6,8,10,12,14,16,18,20,22,24,26,30-Dotriacontatridecaene, 2,6,10,14,19,23,27,31-octamethyl-, (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-; (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene; (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene; 2,6,8,10,12,14,16,18,20,22,24,26,30-Dotriacontatridecaene, 2,6,10,14,19,23,27,31-Octamethyl-, (all-E)-; (all-E)-2,6,10,14,19,23,27,31-Octamethyl-2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene; 2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene; (ALL-E)-LYCOPENE (CONSTITUENT OF LYCOPENE AND TOMATO EXTRACT CONTAINING LYCOPENE); Lycopene, Pharmaceutical Secondary Standard; Certified Reference Material; Lycopene, United States Pharmacopeia (USP) Reference Standard; Lycopene, (7-cis,7-cis,9-cis,9-cis)-isomer -; LYCOPENE FROM BLAKESLEA TRISPORA [FCC]; Lycopene, >=98\\% (HPLC), from tomato; Lycopene from blakeslea trispora; LYCOPENE PREPARATION [USP-RS]; Lycopene, >=90\\%, from tomato; LYCOPENE PREPARATION (USP-RS); Lycopene, analytical standard; lycopene, (13-cis)-isomer; TOMATO LYCOPENE [FHFI]; lycopene, (cis)-isomer; .psi.,.psi.-Carotene; (all-trans)-lycopene; Lycopene, all-trans-; Lycopene preparation; Lycopene all-trans-; all-trans-lycopene; Blakeslea trispora; All trans Lycopene; psi, psi-Carotene; LYCOPENE [WHO-DD]; Psi,psi-carotene; LYCOPENE [MART.]; psi-psi-carotene; LYCOPENE [VANDF]; LYCOPENE (MART.); (all-e)-lycopene; LYCOPENE [INCI]; TOMATO LYCOPENE; UNII-SB0N2N0WV6; LyocpenePowder; trans-Lycopene; Lycopene (VAN); LYCOPENE [MI]; Pro Lycopene; y,y-Carotene; ψ,ψ-Carotene; Aec lycopene; cis-Lycopene; Tox21_112395; Pro-Lycopene; prolycopene; Mexoryl SAQ; Solanorubin; Tomat-O-Red; LYC-O-MATO; SB0N2N0WV6; LYC O MATO; Lycopene 7; Redivivo; Lycopene; LYCOMATO; Ateronon; Lyco Vit; lycored; LYC; Lycopene



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(23)

PlantCyc(10)

代谢反应

862 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(36)

WikiPathways(0)

Plant Reactome(301)

INOH(0)

PlantCyc(524)

COVID-19 Disease Map(0)

PathBank(1)

PharmGKB(0)

211 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 AKT1, ALB, CASP9, CAT, CCND1, GGPS1, GPX1, MSMP, MTOR, NFE2L2, PIK3CA, RUNX2, VEGFA
Peripheral membrane protein 1 MTOR
Endoplasmic reticulum membrane 2 HMGCR, MTOR
Nucleus 9 AKT1, ALB, CASP9, CCND1, KLK3, MTOR, NFE2L2, RUNX2, VEGFA
cytosol 11 AKT1, ALB, CASP9, CAT, CCND1, GGPS1, GPX1, MTOR, NFE2L2, PIK3CA, RUNX2
dendrite 1 MTOR
phagocytic vesicle 2 MTOR, STX8
trans-Golgi network 1 STX8
centrosome 3 ALB, CCND1, NFE2L2
nucleoplasm 6 AKT1, CCND1, GGPS1, MTOR, NFE2L2, RUNX2
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 1 AKT1
Cytoplasmic side 1 MTOR
lamellipodium 2 AKT1, PIK3CA
Multi-pass membrane protein 1 HMGCR
Golgi apparatus membrane 1 MTOR
cell cortex 1 AKT1
cell surface 1 VEGFA
glutamatergic synapse 1 AKT1
Golgi apparatus 3 ALB, NFE2L2, VEGFA
Golgi membrane 1 MTOR
lysosomal membrane 1 MTOR
postsynapse 1 AKT1
Cytoplasm, cytosol 1 NFE2L2
Lysosome 1 MTOR
endosome 1 STX8
plasma membrane 6 AKT1, IFNLR1, KLK3, NFE2L2, PIK3CA, STX8
Membrane 7 AKT1, CAT, HMGCR, IFNLR1, MTOR, STX8, VEGFA
extracellular exosome 3 ALB, CAT, KLK3
Lysosome membrane 1 MTOR
endoplasmic reticulum 4 ALB, HMGCR, STX8, VEGFA
extracellular space 7 ALB, CCL2, CRP, IGF1, KLK3, MSMP, VEGFA
perinuclear region of cytoplasm 3 GGPS1, PIK3CA, STX8
adherens junction 1 VEGFA
bicellular tight junction 1 CCND1
intercalated disc 1 PIK3CA
mitochondrion 3 CASP9, CAT, GPX1
protein-containing complex 5 AKT1, ALB, CASP9, CAT, KLK3
intracellular membrane-bounded organelle 1 CAT
Microsome membrane 1 MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 IFNLR1
Secreted 6 ALB, CCL2, CRP, IGF1, MSMP, VEGFA
extracellular region 7 ALB, CAT, CCL2, CRP, IGF1, KLK3, VEGFA
Mitochondrion outer membrane 1 MTOR
Single-pass membrane protein 1 STX8
mitochondrial outer membrane 1 MTOR
mitochondrial matrix 2 CAT, GPX1
anchoring junction 1 ALB
transcription regulator complex 1 RUNX2
Nucleus membrane 1 CCND1
nuclear membrane 1 CCND1
Secreted, extracellular space, extracellular matrix 1 VEGFA
Z disc 1 GGPS1
microtubule cytoskeleton 1 AKT1
Early endosome 1 STX8
cell-cell junction 1 AKT1
recycling endosome 1 STX8
vesicle 2 AKT1, STX8
Cytoplasm, perinuclear region 1 GGPS1
focal adhesion 1 CAT
spindle 1 AKT1
extracellular matrix 1 VEGFA
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 2 CAT, HMGCR
Nucleus, PML body 1 MTOR
PML body 1 MTOR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 2 KLK3, VEGFA
Late endosome 1 STX8
ciliary basal body 2 AKT1, ALB
chromatin 2 NFE2L2, RUNX2
mediator complex 1 NFE2L2
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
nuclear envelope 1 MTOR
Endomembrane system 2 MTOR, STX8
Peroxisome membrane 1 HMGCR
Cytoplasm, myofibril, sarcomere, Z line 1 GGPS1
SNARE complex 1 STX8
exocytic vesicle 1 IGF1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 ALB
transcription repressor complex 1 CCND1
platelet alpha granule lumen 3 ALB, IGF1, VEGFA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
Single-pass type IV membrane protein 1 STX8
apoptosome 1 CASP9
protein-DNA complex 1 NFE2L2
Cytoplasmic vesicle, phagosome 1 MTOR
cyclin-dependent protein kinase holoenzyme complex 1 CCND1
catalase complex 1 CAT
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
cyclin D1-CDK4 complex 1 CCND1
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
cyclin D1-CDK6 complex 1 CCND1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
ciliary transition fiber 1 ALB
caspase complex 1 CASP9
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Wencheng Zhang, Ziqiao Ji, Guiqiu Hu, Li Yuan, Man Liu, Xian Zhang, Chunhua Wei, Zuyun Dai, Zhongzhou Yang, Chaonan Wang, Xuezheng Wang, Feishi Luan, Shi Liu. Clpf encodes pentatricopeptide repeat protein (PPR5) and regulates pink flesh color in watermelon (Citrullus lanatus L.). TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2024 May; 137(6):126. doi: 10.1007/s00122-024-04619-8. [PMID: 38727833]
  • Xunyu Song, Jun Sun, Hanxiong Liu, Aroosa Mushtaq, Zhoumei Huang, Daotong Li, Lujia Zhang, Fang Chen. Lycopene Alleviates Endoplasmic Reticulum Stress in Steatohepatitis through Inhibition of the ASK1-JNK Signaling Pathway. Journal of agricultural and food chemistry. 2024 Apr; 72(14):7832-7844. doi: 10.1021/acs.jafc.3c08108. [PMID: 38544357]
  • Buli Su, Peixuan Lai, Ming-Rong Deng, Honghui Zhu. Global rewiring of lipid metabolism to produce carotenoid by deleting the transcription factor genes ino2/ino4 in Saccharomyces cerevisiae. International journal of biological macromolecules. 2024 Apr; 264(Pt 1):130400. doi: 10.1016/j.ijbiomac.2024.130400. [PMID: 38412934]
  • Yanan Zhang, Xiaobing Zhai, Honglin Chai, Keyang Liu, Wenzhi Ma, Shiyang Li, Jing Zeng, Mei Yang, Feng Zhou, Surui Zheng, Xia Wu, Bing Xiang, Jinhong Cao, Ehab S Eshak, Can Jiang. Associations of different isomeric forms of serum lycopene with cardiovascular disease and all-cause mortality. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2024 Apr; 94(2):108-119. doi: 10.1024/0300-9831/a000775. [PMID: 36691936]
  • Denny Pellowski, Paula Kusch, Thorsten Henning, Bastian Kochlik, Maria Maares, Amy Schmiedeskamp, Gabriele Pohl, Monika Schreiner, Susanne Baldermann, Hajo Haase, Tanja Schwerdtle, Tilman Grune, Daniela Weber. Postprandial Micronutrient Variability and Bioavailability: An Interventional Meal Study in Young vs. Old Participants. Nutrients. 2024 Feb; 16(5):. doi: 10.3390/nu16050625. [PMID: 38474753]
  • Vojkan M Miljković, Ljubiša Nikolić, Jelena Mrmošanin, Ivana Gajić, Tatjana Mihajilov-Krstev, Jelena Zvezdanović, Milena Miljković. Chemical Profile and Antioxidant and Antimicrobial Activity of Rosa canina L. Dried Fruit Commercially Available in Serbia. International journal of molecular sciences. 2024 Feb; 25(5):. doi: 10.3390/ijms25052518. [PMID: 38473766]
  • Jawaria Jameel, Tauseef Anwar, Saadat Majeed, Huma Qureshi, Ejaz Hussain Siddiqi, Sundas Sana, Wajid Zaman, Hayssam M Ali. Effect of salinity on growth and biochemical responses of brinjal varieties: implications for salt tolerance and antioxidant mechanisms. BMC plant biology. 2024 Feb; 24(1):128. doi: 10.1186/s12870-024-04836-9. [PMID: 38383291]
  • Hao Luo, Yihong Bao, Ping Zhu. Enhancing the functionality of plant-based Yogurt: Integration of lycopene through dual-stage fermentation of soymilk. Food chemistry. 2024 Feb; 434(?):137511. doi: 10.1016/j.foodchem.2023.137511. [PMID: 37742554]
  • Weidong Chen, Yuanqing Li, Min Li, Hai Li, Caifang Chen, Yanzhao Lin. Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014. Journal of health, population, and nutrition. 2024 Feb; 43(1):20. doi: 10.1186/s41043-024-00511-9. [PMID: 38303096]
  • Wanrong Wu, Yanchun Shao, Yeting Wu, Yunxia Gong, Xiaoyan Guan, Baixue Liu, Youyou Lu. New Horizons of Covalent Complex of Plant-Derived Recombinant Human Lactoferrin (OsrhLF) Combined with Different Polyphenols: Formation, Physicochemical Properties, and Gastrointestinal Fate. Journal of agricultural and food chemistry. 2024 Jan; ?(?):. doi: 10.1021/acs.jafc.3c06856. [PMID: 38262965]
  • Huimin Ma, Qi Chen, Haiming Yang, Xiaoli Wan. Effects of lycopene on the growth performance, meat quality, and antioxidant capacity of broiler chickens challenged with aflatoxin B1. Journal of food science. 2024 Jan; 89(1):96-103. doi: 10.1111/1750-3841.16848. [PMID: 37983886]
  • Wenhai Guo, Danping Huang, Shaodong Li. Lycopene alleviates oxidative stress-induced cell injury in human vascular endothelial cells by encouraging the SIRT1/Nrf2/HO-1 pathway. Clinical and experimental hypertension (New York, N.Y. : 1993). 2023 Dec; 45(1):2205051. doi: 10.1080/10641963.2023.2205051. [PMID: 37120838]
  • Margarita Aguilar-Espinosa, José Enrique Ek-Ku, Renata Rivera-Madrid, Marina Vera-Ku. Advancing carotenoid Quantification: A new method for semi-quantitative assessment of β -Carotene and lycopene content in food extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2023 Dec; 1231(?):123929. doi: 10.1016/j.jchromb.2023.123929. [PMID: 38035540]
  • Shaohua Yan, Siyu Chen, Yumiao Liu, Hongbin Liang, Xinlu Zhang, Qiuxia Zhang, Jiancheng Xiu. Associations of serum carotenoids with visceral adiposity index and lipid accumulation product: a cross-sectional study based on NHANES 2001-2006. Lipids in health and disease. 2023 Nov; 22(1):209. doi: 10.1186/s12944-023-01945-6. [PMID: 38037060]
  • Jadwiga Hamulka, Agnieszka Sulich, Magdalena Górnicka, Marta Jeruszka-Bielak. Changes in Plasma Carotenoid Concentrations during the AntioxObesity Weight Reduction Program among Adults with Excessive Body Weight. Nutrients. 2023 Nov; 15(23):. doi: 10.3390/nu15234890. [PMID: 38068747]
  • Riccardo Fedeli, Ludovica Marotta, Luca Frattaruolo, Alice Panti, Gabriele Carullo, Fabio Fusi, Simona Saponara, Sandra Gemma, Stefania Butini, Anna Rita Cappello, Andrea Vannini, Giuseppe Campiani, Stefano Loppi. Nutritionally enriched tomatoes (Solanum lycopersicum L.) grown with wood distillate: chemical and biological characterization for quality assessment. Journal of food science. 2023 Nov; ?(?):. doi: 10.1111/1750-3841.16829. [PMID: 37961008]
  • Rong-Rui Wei, Qing-Yuan Lin, Mozili Adu, Hui-Lian Huang, Zhi-Hong Yan, Feng Shao, Guo-Yue Zhong, Zhong-Li Zhang, Zhi-Pei Sang, Lan Cao, Qin-Ge Ma. The sources, properties, extraction, biosynthesis, pharmacology, and application of lycopene. Food & function. 2023 Nov; 14(22):9974-9998. doi: 10.1039/d3fo03327a. [PMID: 37916682]
  • Hao-Ran Wang, Mu-Zi Li, Jia-Gen Cui, Hao Zhang, Yi Zhao, Jin-Long Li. Lycopene Prevents Phthalate-Induced Cognitive Impairment via Modulating Ferroptosis. Journal of agricultural and food chemistry. 2023 Nov; 71(44):16727-16738. doi: 10.1021/acs.jafc.3c04801. [PMID: 37871231]
  • Xinying Zhang, Shuting Chen, Ying Lin, Wenjie Li, Denggang Wang, Shupeng Ruan, Yuxin Yang, Shuli Liang. Metabolic Engineering of Pichia pastoris for High-Level Production of Lycopene. ACS synthetic biology. 2023 10; 12(10):2961-2972. doi: 10.1021/acssynbio.3c00294. [PMID: 37782893]
  • Marco Dainelli, Sara Pignattelli, Nadia Bazihizina, Sara Falsini, Alessio Papini, Ivan Baccelli, Stefano Mancuso, Andrea Coppi, Maria Beatrice Castellani, Ilaria Colzi, Cristina Gonnelli. Can microplastics threaten plant productivity and fruit quality? Insights from Micro-Tom and Micro-PET/PVC. The Science of the total environment. 2023 Oct; 895(?):165119. doi: 10.1016/j.scitotenv.2023.165119. [PMID: 37364840]
  • Ying Wang, Siqi Li, Ze Zhou, Lifen Sun, Jing Sun, Chuanpu Shen, Ranran Gao, Jingyuan Song, Xiangdong Pu. The Functional Characteristics and Soluble Expression of Saffron CsCCD2. International journal of molecular sciences. 2023 Oct; 24(20):. doi: 10.3390/ijms242015090. [PMID: 37894770]
  • Ki-Nam Yoon, Yeong-Seok Yoon, Hae-Jung Hong, Jong-Heum Park, Beom-Seok Song, Jong-Bang Eun, Jae-Kyung Kim. Gamma irradiation delays tomato (Solanum lycopersicum) ripening by inducing transcriptional changes. Journal of the science of food and agriculture. 2023 Oct; 103(13):6640-6653. doi: 10.1002/jsfa.12760. [PMID: 37267467]
  • Bangmian Du, Mengjuan Sun, Wenyang Hui, Chengjia Xie, Xian Xu. Recent Advances on Key Enzymes of Microbial Origin in the Lycopene Biosynthesis Pathway. Journal of agricultural and food chemistry. 2023 Sep; 71(35):12927-12942. doi: 10.1021/acs.jafc.3c03942. [PMID: 37609695]
  • Nancy E Moran, Joshua Wade, Rachel Stroh, Barbara Stoll, Gregory Guthrie, Amy B Hair, Douglas G Burrin. Preterm Pigs Fed Donor Human Milk Have Greater Liver Beta-carotene Concentrations than Pigs Fed Infant Formula. The Journal of nutrition. 2023 Sep; ?(?):. doi: 10.1016/j.tjnut.2023.08.026. [PMID: 37666415]
  • Ana Arruabarrena, Joanna Lado, Matías González-Arcos, Sabina Vidal. Targeted disruption of tomato chromoplast-specific lycopene β-cyclase (CYC-B) gene promotes early accumulation of lycopene in fruits and enhanced postharvest cold tolerance. Plant biotechnology journal. 2023 Aug; ?(?):. doi: 10.1111/pbi.14169. [PMID: 37654005]
  • Sonal B More, Mahalaxmi Mohan, Prayrna Kulkarni, Kedar C Ahire. Lycopene attenuates silver nanoparticle-induced liver injury in albino mice. Journal of biochemical and molecular toxicology. 2023 Aug; ?(?):e23500. doi: 10.1002/jbt.23500. [PMID: 37555715]
  • Iness Jabri Karoui, Emna Chaabani, Imen Dali, Abdelkarim Aydi, Majdi Hammami, Manef Abderrabba. Optimization of antioxidant and lycopene extraction from tomato pomace using Hansen solubility parameters and its application in chicken meat preservation. Journal of food science. 2023 Aug; ?(?):. doi: 10.1111/1750-3841.16722. [PMID: 37548649]
  • Gamal A Salem, Amany Abdel-Rahman Mohamed, Safaa I Khater, Ahmed E Noreldin, Manal Alosaimi, Wafa S Alansari, Ghalia Shamlan, Areej A Eskandrani, Marwa Mahmoud Awad, Rehab Ahmed Ahmed El-Shaer, Mohamed A Nassan, Mahmoud Mostafa, Tarek Khamis. Enhancement of biochemical and genomic pathways through lycopene-loaded nano-liposomes: Alleviating insulin resistance, hepatic steatosis, and autophagy in obese rats with non-alcoholic fatty liver disease: Involvement of SMO, GLI-1, and PTCH-1 genes. Gene. 2023 Jul; 883(?):147670. doi: 10.1016/j.gene.2023.147670. [PMID: 37516284]
  • Mohammad Zamani, Farimah Behmanesh Nia, Kimia Ghaedi, Saba Mohammadpour, Niusha Amirani, Kian Goudarzi, Kosar Hosseini, Matin Ghanavati, Damoon Ashtary-Larky. The effects of lycopene and tomato consumption on cardiovascular risk factors in adults: a Grade assessment systematic review and meta-analysis. Current pharmaceutical design. 2023 Jul; ?(?):. doi: 10.2174/1381612829666230726112510. [PMID: 37496241]
  • Pedro Brivaldo Viana da Silva, Lívia Beatriz Brenelli, Lilian Regina Barros Mariutti. Waste and by-products as sources of lycopene, phytoene, and phytofluene - Integrative review with bibliometric analysis. Food research international (Ottawa, Ont.). 2023 07; 169(?):112838. doi: 10.1016/j.foodres.2023.112838. [PMID: 37254412]
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  • Shanshan Wang, Wenjiang He, Wenzhi Li, Jin-Rong Zhou, Zhiyun Du. Combination of Lycopene and Curcumin Synergistically Alleviates Testosterone-Propionate-Induced Benign Prostatic Hyperplasia in Sprague Dawley Rats via Modulating Inflammation and Proliferation. Molecules (Basel, Switzerland). 2023 Jun; 28(13):. doi: 10.3390/molecules28134900. [PMID: 37446563]
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  • Hussein G Daood, Szilvia Ráth, Gábor Palotás, Gábor Halász, Kamiran Hamow, Lajos Helyes. Efficient HPLC Separation on a Core-C30 Column with MS2 Characterization of Isomers, Derivatives and Unusual Carotenoids from Tomato Products. Journal of chromatographic science. 2022 Apr; 60(4):336-347. doi: 10.1093/chromsci/bmab085. [PMID: 34184033]
  • Hongmin Lu, Heng Su, Yachen Liu, Kai Yin, Dongxu Wang, Baoying Li, Yu Wang, Mingwei Xing. NLRP3 inflammasome is involved in the mechanism of the mitigative effect of lycopene on sulfamethoxazole-induced inflammatory damage in grass carp kidneys. Fish & shellfish immunology. 2022 Apr; 123(?):348-357. doi: 10.1016/j.fsi.2022.03.018. [PMID: 35314330]
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  • Paula Aguilera, Ninozhka Becerra, Marysol Alvear, Nancy Ortiz, Alessandra Turrini, Concepción Azcón-Aguilar, Miguel López-Gómez, Juan K Romero, Mariajosé Massri, Alex Seguel, María de La Luz Mora, Fernando Borie. Arbuscular mycorrhizal fungi from acidic soils favors production of tomatoes and lycopene concentration. Journal of the science of food and agriculture. 2022 Apr; 102(6):2352-2358. doi: 10.1002/jsfa.11573. [PMID: 34636032]
  • Brian T Scarpitti, Chureeporn Chitchumroonchokchai, Steven K Clinton, Zachary D Schultz. In Vitro Imaging of Lycopene Delivery to Prostate Cancer Cells. Analytical chemistry. 2022 03; 94(12):5106-5112. doi: 10.1021/acs.analchem.1c05442. [PMID: 35289593]
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