4-Nitroquinoline 1-oxide (BioDeep_00000406304)
Main id: BioDeep_00000001658
natural product
代谢物信息卡片
4-Nitroquinoline 1-oxide
化学式: C9H6N2O3 (190.0378406)
中文名称: 4-硝基喹啉-N-氧化物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C(=CC=[N+]2[O-])[N+](=O)[O-]
InChI: InChI=1S/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H
描述信息
D009676 - Noxae > D002273 - Carcinogens
D009676 - Noxae > D009153 - Mutagens
同义名列表
2 个代谢物同义名
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:16907
- KEGG: C03474
- PubChem: 5955
- ChEMBL: CHEMBL127655
- MeSH: 4-Nitroquinoline-1-oxide
- CAS: 52002-25-2
- CAS: 56-57-5
- MoNA: Bruker_HCD_library001078
- MoNA: VF-NPL-QTOF004122
- MoNA: VF-NPL-QTOF004121
- MoNA: VF-NPL-QTOF004120
- MoNA: VF-NPL-QEHF000054
- MoNA: VF-NPL-QEHF000053
- MoNA: VF-NPL-QEHF000052
- MoNA: VF-NPL-QEHF000051
- MoNA: VF-NPL-QEHF000050
- MoNA: VF-NPL-QEHF000049
- PubChem: 6291
- PDB-CCD: YHX
- 3DMET: B00590
- NIKKAJI: J2.321C
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Maria Alonso-Jauregui, Elena González-Peñas, Adela López de Cerain, Ariane Vettorazzi. Genotoxicity of 12 Mycotoxins by the SOS/umu Test: Comparison of Liver and Kidney S9 Fraction.
Toxins.
2022 06; 14(6):. doi:
10.3390/toxins14060400. [PMID: 35737061] - Yuanyuan Li, Yanting Wang, Jie Li, Zihang Ling, Wei Chen, Liping Zhang, Qinchao Hu, Tong Wu, Bin Cheng, Yun Wang, Juan Xia. Tacrolimus inhibits oral carcinogenesis through cell cycle control.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Jul; 139(?):111545. doi:
10.1016/j.biopha.2021.111545. [PMID: 33873145] - Yanlin Jian, He Eun Forbes, Fabian Hulpia, Martijn D P Risseeuw, Guy Caljon, Hélène Munier-Lehmann, Helena I M Boshoff, Serge Van Calenbergh. 2-((3,5-Dinitrobenzyl)thio)quinazolinones: Potent Antimycobacterial Agents Activated by Deazaflavin (F420)-Dependent Nitroreductase (Ddn).
Journal of medicinal chemistry.
2021 01; 64(1):440-457. doi:
10.1021/acs.jmedchem.0c01374. [PMID: 33347317] - Aparajita Verma, Vui King Vincent-Chong, Hendrik DeJong, Pamela A Hershberger, Mukund Seshadri. Impact of dietary vitamin D on initiation and progression of oral cancer.
The Journal of steroid biochemistry and molecular biology.
2020 05; 199(?):105603. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Jul; 60(?):152886. doi:
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Clinical oral investigations.
2019 May; 23(5):2287-2301. doi:
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European journal of medicinal chemistry.
2019 Feb; 164(?):59-76. doi:
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Anticancer research.
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Molecular carcinogenesis.
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Brazilian journal of biology = Revista brasleira de biologia.
2018 May; 78(2):345-350. doi:
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Cancer prevention research (Philadelphia, Pa.).
2018 04; 11(4):191-202. doi:
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Medical oncology (Northwood, London, England).
2018 Mar; 35(4):54. doi:
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The Biochemical journal.
2017 08; 474(17):3011-3025. doi:
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Journal of cellular physiology.
2017 Jun; 232(6):1360-1367. doi:
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Environmental toxicology.
2017 Mar; 32(3):799-812. doi:
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Anti-cancer agents in medicinal chemistry.
2017; 17(5):712-718. doi:
10.2174/1871520616666160906092502. [PMID: 27600790] - Yoonhwa Jeong, Mina Jung, Myeung Ju Kim, Cheol Ho Hwang. A 4-Nitroquinoleneoxide-Induced Pleurotus eryngii Mutant Variety Increases Pin1 Expression in Rat Brain.
Journal of medicinal food.
2017 Jan; 20(1):65-70. doi:
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Bioorganic & medicinal chemistry letters.
2016 08; 26(16):4086-91. doi:
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BMC complementary and alternative medicine.
2016 Jul; 16(?):229. doi:
10.1186/s12906-016-1186-x. [PMID: 27430309] - Agata Skrzypczak, Natalia Przystupa, Anna Zgadzaj, Andrzej Parzonko, Katarzyna Sykłowska-Baranek, Katarzyna Paradowska, Grzegorz Nałęcz-Jawecki. Antigenotoxic, anti-photogenotoxic and antioxidant activities of natural naphthoquinone shikonin and acetylshikonin and Arnebia euchroma callus extracts evaluated by the umu-test and EPR method.
Toxicology in vitro : an international journal published in association with BIBRA.
2015 Dec; 30(1 Pt B):364-72. doi:
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Mutation research. Genetic toxicology and environmental mutagenesis.
2015 Jan; 778(?):1-5. doi:
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International journal of clinical and experimental pathology.
2015; 8(4):3529-42. doi:
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Toxicology mechanisms and methods.
2015; 25(7):532-7. doi:
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Asian Pacific journal of cancer prevention : APJCP.
2015; 16(10):4169-72. doi:
10.7314/apjcp.2015.16.10.4169. [PMID: 26028067] - Ana Rita Ribeiro Barcessat, Isaac Huang, Gustavo Davi Rabelo, Flávia Cristina Perillo Rosin, Luciana Gonçalves Valente Ferreira, João Gualberto de Cerqueira Luz, Luciana Corrêa. Systemic toxic effects during early phases of topical 4-NQO-induced oral carcinogenesis in rats.
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2014 Nov; 43(10):770-7. doi:
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G3 (Bethesda, Md.).
2014 Oct; 4(12):2483-92. doi:
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Archives of oral biology.
2014 Aug; 59(8):815-21. doi:
10.1016/j.archoralbio.2014.04.013. [PMID: 24863658] - Mick D Fellows, Angela McDermott, Katie R Clare, Ann Doherty, Marilyn J Aardema. The spectral karyotype of L5178Y TK⁺/⁻ mouse lymphoma cells clone 3.7.2C and factors affecting mutant frequency at the thymidine kinase (tk) locus in the microtitre mouse lymphoma assay.
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Molecular carcinogenesis.
2013 Jan; 52(1):49-56. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Dec; 50(12):4479-86. doi:
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In vivo (Athens, Greece).
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Toxicology and applied pharmacology.
2012 Jul; 262(2):107-16. doi:
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Asian Pacific journal of cancer prevention : APJCP.
2012; 13(8):4107-12. doi:
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Bioscience, biotechnology, and biochemistry.
2012; 76(10):1993-5. doi:
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Medical oncology (Northwood, London, England).
2011 Dec; 28(4):1163-8. doi:
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Environmental toxicology and pharmacology.
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Biochimica et biophysica acta.
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Birth defects research. Part B, Developmental and reproductive toxicology.
2011 Apr; 92(2):152-87. doi:
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Drug and chemical toxicology.
2011 Apr; 34(2):116-9. doi:
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Cancer prevention research (Philadelphia, Pa.).
2011 Feb; 4(2):230-7. doi:
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Marine drugs.
2010 Nov; 8(11):2795-809. doi:
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Archives of biochemistry and biophysics.
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
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Fungal genetics and biology : FG & B.
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Journal of ethnopharmacology.
2009 Feb; 122(1):136-42. doi:
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Drug and chemical toxicology.
2009; 32(4):411-6. doi:
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Diabetes/metabolism research and reviews.
2008 Jul; 24(5):371-7. doi:
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Fungal genetics and biology : FG & B.
2008 Jun; 45(6):851-60. doi:
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Chemico-biological interactions.
2008 Apr; 172(3):224-34. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2008 Mar; 15(3):216-20. doi:
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Phytotherapy research : PTR.
2008 Jan; 22(1):77-81. doi:
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International journal of food microbiology.
2007 Aug; 118(1):62-8. doi:
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BMC cancer.
2007 Mar; 7(?):40. doi:
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Life sciences.
2007 Feb; 80(12):1080-6. doi:
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International journal of pharmaceutics.
2006 Aug; 320(1-2):45-52. doi:
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Chemico-biological interactions.
2006 Aug; 162(2):149-56. doi:
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The journal of physical chemistry. B.
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Shanghai kou qiang yi xue = Shanghai journal of stomatology.
2005 Jun; 14(3):289-92. doi:
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Journal of controlled release : official journal of the Controlled Release Society.
2005 May; 104(1):167-79. doi:
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Chemico-biological interactions.
2004 Oct; 149(2-3):81-7. doi:
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Nutrition journal.
2004 May; 3(?):5. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2004 Feb; 18(1):29-35. doi:
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Cancer letters.
2003 Sep; 199(2):121-9. doi:
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Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections.
2002 May; 384(?):257-9. doi:
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Genetika.
2002 Mar; 38(3):306-9. doi:
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Genetika.
2002 Mar; 38(3):422-5. doi:
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Environmental toxicology.
2002; 17(3):187-94. doi:
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Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
2002; 21(1):33-44. doi:
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Fitoterapia.
2001 Jun; 72(5):524-31. doi:
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Cancer research.
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Electrophoresis.
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Journal of agricultural and food chemistry.
2001 Jan; 49(1):336-41. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2000 May; 38(5):467-71. doi:
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Mutation research.
1999 Aug; 444(2):321-36. doi:
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Journal of natural products.
1999 Jul; 62(7):972-5. doi:
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Environmental and molecular mutagenesis.
1999; 33(4):325-7. doi:
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Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
1999; 18(2):119-25. doi:
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Applied and environmental microbiology.
1998 Oct; 64(10):3983-8. doi:
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Experimental cell research.
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Journal of photochemistry and photobiology. B, Biology.
1998 May; 43(2):152-7. doi:
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1998 Feb; 27(2):53-8. doi:
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Mutation research.
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Archives of toxicology.
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Electrophoresis.
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Bioscience, biotechnology, and biochemistry.
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Nutrition and cancer.
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Research communications in molecular pathology and pharmacology.
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1994 Oct; 32(10):905-9. doi:
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1994 Jul; 308(2):117-25. doi:
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Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].
1994 May; 28(3):147-50. doi:
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Mutagenesis.
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International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
1994; 64(3):181-4. doi:
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Human cell.
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