procyanidin B2 (BioDeep_00000003541)

Main id: BioDeep_00000000414

Secondary id: BioDeep_00000017259, BioDeep_00000020178, BioDeep_00000266658

natural product PANOMIX_OTCML-2023 PANOMIX-Anthocyanidin


代谢物信息卡片


(2S,3S)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-4-yl]chromane-3,5,7-triol

化学式: C30H26O12 (578.1424)
中文名称: 原花青素B2, 原花青素B1
谱图信息: 最多检出来源 Viridiplantae(plant) 47.71%

分子结构信息

SMILES: C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O
InChI: InChI=1/C30H26O12/c31-13-7-20(37)24-23(8-13)41-29(12-2-4-16(33)19(36)6-12)27(40)26(24)25-21(38)10-17(34)14-9-22(39)28(42-30(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,22,26-29,31-40H,9H2/t22-,26-,27-,28-,29-/m1/s1

描述信息

Annotation level-1
Acquisition and generation of the data is financially supported in part by CREST/JST.
Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.
Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities.

同义名列表

9 个代谢物同义名

procyanidin B2; PROCYANIDINB2; Procyanidin B2, (+)-; (2S,3S)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-4-yl]chromane-3,5,7-triol; Epicatechin-(4beta->8)-ent-epicatechin; Procyanidin B1; Proanthocyanidin B2; Epicatechin-(4beta->8)-ent-epicatechin; Procyanidin B2



数据库引用编号

72 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

124 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 AKT1, BCL2, CASP1, CASP3, MAPK14, MTOR, NFE2L2, NLRP3, PIK3CA, PPARG, PRKAA2, PTGS2, RELA, SIRT1, TLR4
Peripheral membrane protein 3 MFGE8, MTOR, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 4 BCL2, HMOX1, MTOR, PTGS2
Nucleus 12 AKT1, BCL2, CASP3, HMOX1, MAPK14, MTOR, NFE2L2, NLRP3, PPARG, PRKAA2, RELA, SIRT1
cytosol 14 AKT1, BCL2, CASP1, CASP3, HMOX1, MAPK14, MTOR, NFE2L2, NLRP3, PIK3CA, PPARG, PRKAA2, RELA, SIRT1
dendrite 2 MTOR, PRKAA2
phagocytic vesicle 1 MTOR
centrosome 1 NFE2L2
nucleoplasm 10 AKT1, CASP3, HMOX1, MAPK14, MTOR, NFE2L2, PPARG, PRKAA2, RELA, SIRT1
RNA polymerase II transcription regulator complex 2 NFE2L2, PPARG
Cell membrane 4 AKT1, CASP1, TLR4, TNF
Cytoplasmic side 2 HMOX1, MTOR
lamellipodium 2 AKT1, PIK3CA
Golgi apparatus membrane 2 MTOR, NLRP3
cell cortex 1 AKT1
cell surface 2 TLR4, TNF
glutamatergic synapse 4 AKT1, CASP3, MAPK14, RELA
Golgi apparatus 2 NFE2L2, PRKAA2
Golgi membrane 2 MTOR, NLRP3
lysosomal membrane 1 MTOR
neuronal cell body 3 CASP3, PRKAA2, TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 2 NFE2L2, NLRP3
Lysosome 1 MTOR
plasma membrane 6 AKT1, CASP1, NFE2L2, PIK3CA, TLR4, TNF
Membrane 8 AKT1, BCL2, HMOX1, MFGE8, MTOR, NLRP3, PRKAA2, TLR4
axon 2 CCK, PRKAA2
caveola 1 PTGS2
extracellular exosome 1 MFGE8
Lysosome membrane 1 MTOR
endoplasmic reticulum 4 BCL2, HMOX1, NLRP3, PTGS2
extracellular space 5 CCK, HMOX1, IL6, MFGE8, TNF
perinuclear region of cytoplasm 4 HMOX1, PIK3CA, PPARG, TLR4
intercalated disc 1 PIK3CA
mitochondrion 4 BCL2, MAPK14, NLRP3, SIRT1
protein-containing complex 4 AKT1, BCL2, CASP1, PTGS2
intracellular membrane-bounded organelle 1 PPARG
Microsome membrane 2 MTOR, PTGS2
postsynaptic density 1 CASP3
chromatin silencing complex 1 SIRT1
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 TLR4
Secreted 4 CCK, IL6, MFGE8, NLRP3
extracellular region 6 CCK, IL6, MAPK14, MFGE8, NLRP3, TNF
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 3 BCL2, HMOX1, MTOR
transcription regulator complex 1 RELA
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 3 MFGE8, TLR4, TNF
Extracellular vesicle 1 MFGE8
microtubule cytoskeleton 1 AKT1
nucleolus 2 CASP1, SIRT1
Early endosome 1 TLR4
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
heterochromatin 1 SIRT1
Membrane raft 1 TNF
pore complex 1 BCL2
microtubule 1 CASP1
spindle 1 AKT1
Nucleus, PML body 2 MTOR, SIRT1
PML body 2 MTOR, SIRT1
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 MFGE8
nuclear speck 2 MAPK14, PRKAA2
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 2 CASP1, NLRP3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 2 PTGS2, SIRT1
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 2 PPARG, TLR4
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 4 NFE2L2, PPARG, RELA, SIRT1
mediator complex 1 NFE2L2
phagocytic cup 2 TLR4, TNF
spindle pole 1 MAPK14
fibrillar center 1 SIRT1
nuclear envelope 2 MTOR, SIRT1
Endomembrane system 2 MTOR, NLRP3
microtubule organizing center 1 NLRP3
cytoplasmic stress granule 1 PRKAA2
euchromatin 1 SIRT1
myelin sheath 1 BCL2
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
endoplasmic reticulum lumen 3 IL6, MFGE8, PTGS2
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
Single-pass type IV membrane protein 1 HMOX1
AIM2 inflammasome complex 1 CASP1
protein-DNA complex 1 NFE2L2
death-inducing signaling complex 1 CASP3
canonical inflammasome complex 1 CASP1
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
nucleotide-activated protein kinase complex 1 PRKAA2
acrosomal membrane 1 MFGE8
Cytoplasmic vesicle, secretory vesicle, acrosome membrane 1 MFGE8
Cytoplasmic vesicle, phagosome 1 MTOR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
NF-kappaB p50/p65 complex 1 RELA
NF-kappaB complex 1 RELA
IPAF inflammasome complex 1 CASP1
NLRP1 inflammasome complex 1 CASP1
protease inhibitor complex 1 CASP1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1


文献列表

  • Yanxia Yu, Chunying Zuo, Mingrui Li, Yuanyuan Tang, Lingxi Li, Fang Wang, Shuting Zhang, Baoshan Sun. Novel l-Cysteine Incomplete Degradation Method for Preparation of Procyanidin B2-3'-O-Gallate and Exploration of its in Vitro Anti-inflammatory Activity and in Vivo Tissue Distribution. Journal of agricultural and food chemistry. 2024 Feb; 72(8):4023-4034. doi: 10.1021/acs.jafc.3c05616. [PMID: 38357881]
  • Junren Chen, Kexin Zhong, Yiqi Jing, Shengmeng Liu, Siqi Qin, Fu Peng, Dan Li, Cheng Peng. Procyanidin B2: A promising multi-functional food-derived pigment for human diseases. Food chemistry. 2023 Sep; 420(?):136101. doi: 10.1016/j.foodchem.2023.136101. [PMID: 37059021]
  • Yongqiang Zhou, Sumei Li, Bowen Pan, Junwei Xiao, Tingting Tang, Shouxia Xie, Xin Yang, Guihui Wu, Jinxin Xiao, Jian Yang, Ying Zhou, Yuxin Pang, Ying Wei. Antiviral activity and active components of the leaves from Sabia parviflora Wall. ex Roxb. Natural product research. 2023 Aug; ?(?):1-4. doi: 10.1080/14786419.2023.2239995. [PMID: 37526578]
  • Binhong Hu, Songqing Liu, Yuanyue Luo, Jingyu Pu, Xin Deng, Wenjing Zhou, Yuqing Dong, Yichuan Ma, Gang Wang, Fan Yang, Tianhui Zhu, Jiasui Zhan. Procyanidin B2 alleviates uterine toxicity induced by cadmium exposure in rats: The effect of oxidative stress, inflammation, and gut microbiota. Ecotoxicology and environmental safety. 2023 Jul; 263(?):115290. doi: 10.1016/j.ecoenv.2023.115290. [PMID: 37515969]
  • Tharindu L Suraweera, J P Jose Merlin, Graham Dellaire, Zhaolin Xu, H P Vasantha Rupasinghe. Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro. International journal of molecular sciences. 2023 Feb; 24(4):. doi: 10.3390/ijms24043676. [PMID: 36835090]
  • Safa Rguez, Majdi Hammami, Wissem Aidi Wannes, Ibtissem Hamrouni Sellami. Bioguided fractionation of procyanidin B2 as potent anti coxsackie virus B and Herpes simplex from cypress (Cupressus sempervirens L.). International journal of environmental health research. 2022 Oct; ?(?):1-10. doi: 10.1080/09603123.2022.2137475. [PMID: 36264708]
  • Jinqian Chen, Hao Zhang, Xia Hu, Mengyuan Xu, Yanjun Su, Chunze Zhang, Yuan Yue, Xiaomin Zhang, Xinyu Wang, Wei Cui, Zhenyu Zhao, Xichuan Li. Phloretin exhibits potential food-drug interactions by inhibiting human UDP-glucuronosyltransferases in vitro. Toxicology in vitro : an international journal published in association with BIBRA. 2022 Oct; 84(?):105447. doi: 10.1016/j.tiv.2022.105447. [PMID: 35868516]
  • Chuanping Zhao, Jiamei Tang, Xiaoya Li, Zihan Yan, Liangliang Zhao, Wenbo Lang, Chunmao Yuan, Chengyan Zhou. Beneficial effects of procyanidin B2 on adriamycin-induced nephrotic syndrome mice: the multi-action mechanism for ameliorating glomerular permselectivity injury. Food & function. 2022 Aug; 13(16):8436-8464. doi: 10.1039/d1fo03616e. [PMID: 35861207]
  • Li Huang, Kun-Peng Yang, Qing Zhao, Hui-Jing Li, Jin-Yi Wang, Yan-Chao Wu. Corrosion resistance and antibacterial activity of procyanidin B2 as a novel environment-friendly inhibitor for Q235 steel in 1 M HCl solution. Bioelectrochemistry (Amsterdam, Netherlands). 2022 Feb; 143(?):107969. doi: 10.1016/j.bioelechem.2021.107969. [PMID: 34637961]
  • Xinchuan Zheng, Yongjun Yang, Yongling Lu, Qian Chen. Affinity-Guided Isolation and Identification of Procyanidin B2 from Mangosteen (Garcinia mangostana L.) Rinds and its In Vitro LPS Binding and Neutralization Activities. Plant foods for human nutrition (Dordrecht, Netherlands). 2021 Dec; 76(4):442-448. doi: 10.1007/s11130-021-00920-9. [PMID: 34480677]
  • Li Ma, Chengxu Li, Shuai Lian, Bin Xu, Hongming Lv, Yanzhi Liu, Jingjing Lu, Hong Ji, Shize Li, Jingru Guo, Huanmin Yang. Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy. Journal of cellular and molecular medicine. 2021 08; 25(16):8015-8027. doi: 10.1111/jcmm.16733. [PMID: 34155807]
  • Yue Li, Zhengqi Cheng, Ke Wang, Xue Zhu, Youmna Ali, Wenying Shu, Xiaofeng Bao, Ling Zhu, Xiaohui Fan, Michael Murray, Fanfan Zhou. Procyanidin B2 and rutin in Ginkgo biloba extracts protect human retinal pigment epithelial (RPE) cells from oxidative stress by modulating Nrf2 and Erk1/2 signalling. Experimental eye research. 2021 06; 207(?):108586. doi: 10.1016/j.exer.2021.108586. [PMID: 33891955]
  • Dimas Rahadian Aji Muhammad, Emmy Tuenter, Graha Darma Patria, Kenn Foubert, Luc Pieters, Koen Dewettinck. Phytochemical composition and antioxidant activity of Cinnamomum burmannii Blume extracts and their potential application in white chocolate. Food chemistry. 2021 Mar; 340(?):127983. doi: 10.1016/j.foodchem.2020.127983. [PMID: 32919354]
  • Chun-Ying Qiao, Ying Li, Yue Shang, Min Jiang, Jian Liu, Zi-Ying Zhan, Huan Ye, Yong-Ce Lin, Jing-Ya Jiao, Rong-Hui Sun, Zhi-Hong Zhang, Mei-Hua Piao, Yan-Ling Wu, Ji-Xing Nan, Li-Hua Lian. Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages. Inflammopharmacology. 2020 Dec; 28(6):1481-1493. doi: 10.1007/s10787-020-00758-8. [PMID: 33006110]
  • Xin Nie, Weiqi Tang, Zihui Zhang, Chunmiao Yang, Lei Qian, Xinya Xie, Erjiao Qiang, Jingyang Zhao, Wenfei Zhao, Lei Xiao, Nanping Wang. Procyanidin B2 mitigates endothelial endoplasmic reticulum stress through a PPARδ-Dependent mechanism. Redox biology. 2020 10; 37(?):101728. doi: 10.1016/j.redox.2020.101728. [PMID: 32961442]
  • Alice Franchi, Marco Pedrazzi, Alessandro Alberto Casazza, Enrico Millo, Gianluca Damonte, Annalisa Salis, Nara Liessi, Franco Onofri, Antonella Marte, Silvia Casagrande, Roberta De Tullio, Patrizia Perego, Monica Averna. A Bioactive Olive Pomace Extract Prevents the Death of Murine Cortical Neurons Triggered by NMDAR Over-Activation. Molecules (Basel, Switzerland). 2020 09; 25(19):. doi: 10.3390/molecules25194385. [PMID: 32987671]
  • Filis Morina, Sachiko Hirota, Umeo Takahama. Contribution of amylose-procyanidin complexes to slower starch digestion of red-colored rice prepared by cooking with adzuki bean. International journal of food sciences and nutrition. 2020 Sep; 71(6):715-725. doi: 10.1080/09637486.2020.1719389. [PMID: 31986936]
  • Catherine P Bondonno, Nicola P Bondonno, Sujata Shinde, Armaghan Shafaei, Mary C Boyce, Ewald Swinny, Steele R Jacob, Kevin Lacey, Richard J Woodman, Kevin D Croft, Michael J Considine, Jonathan M Hodgson. Phenolic composition of 91 Australian apple varieties: towards understanding their health attributes. Food & function. 2020 Aug; 11(8):7115-7125. doi: 10.1039/d0fo01130d. [PMID: 32744555]
  • Jian-Xing Liu, Chen Yang, Ze-Jian Liu, Hong-Yong Su, Wei-Huang Zhang, Qingjun Pan, Hua-Feng Liu. Protection of procyanidin B2 on mitochondrial dynamics in sepsis associated acute kidney injury via promoting Nrf2 nuclear translocation. Aging. 2020 08; 12(15):15638-15655. doi: 10.18632/aging.103726. [PMID: 32805725]
  • Yifei Wang, Peter de B Harrington, Pei Chen. Quantitative analysis of proanthocyanidins in cocoa using cysteamine-induced thiolysis and reversed-phase UPLC. Analytical and bioanalytical chemistry. 2020 Jul; 412(18):4343-4352. doi: 10.1007/s00216-020-02669-7. [PMID: 32372274]
  • Zhi Jie Deng, Jing Fang Zhao, Feng Huang, Gui Li Sun, Wei Gao, Li Lu, De Qiang Xiao. Protective Effect of Procyanidin B2 on Acute Liver Injury Induced by Aflatoxin B 1 in Rats. Biomedical and environmental sciences : BES. 2020 Apr; 33(4):238-247. doi: 10.3967/bes2020.033. [PMID: 32438961]
  • Guillaume Billerach, Laurent Rouméas, Eric Dubreucq, Hélène Fulcrand. Furanolysis with Menthofuran: A New Depolymerization Method for Analyzing Condensed Tannins. Journal of agricultural and food chemistry. 2020 Mar; 68(10):2917-2926. doi: 10.1021/acs.jafc.9b00497. [PMID: 31013083]
  • Yasuyuki Fujii, Yoshitomo Suhara, Yusuke Sukikara, Tomohiro Teshima, Yoshihisa Hirota, Kenjiro Yoshimura, Naomi Osakabe. Elucidation of the Interaction between Flavan-3-ols and Bovine Serum Albumin and Its Effect on Their In-Vitro Cytotoxicity. Molecules (Basel, Switzerland). 2019 Oct; 24(20):. doi: 10.3390/molecules24203667. [PMID: 31614668]
  • Albert Ribas-Agustí, Olga Martín-Belloso, Robert Soliva-Fortuny, Pedro Elez-Martínez. Enhancing hydroxycinnamic acids and flavan-3-ol contents by pulsed electric fields without affecting quality attributes of apple. Food research international (Ottawa, Ont.). 2019 07; 121(?):433-440. doi: 10.1016/j.foodres.2018.11.057. [PMID: 31108767]
  • Ermes Lo Piccolo, Ambra Viviani, Lucia Guidi, Damiano Remorini, Rossano Massai, Rodolfo Bernardi, Marco Landi. Discerning between Two Tuscany (Italy) Ancient Apple cultivars, 'Rotella' and 'Casciana', through Polyphenolic Fingerprint and Molecular Markers. Molecules (Basel, Switzerland). 2019 May; 24(9):. doi: 10.3390/molecules24091758. [PMID: 31067628]
  • Miguel Rebollo-Hernanz, Qiaozhi Zhang, Yolanda Aguilera, Maria A Martín-Cabrejas, Elvira Gonzalez de Mejia. Cocoa Shell Aqueous Phenolic Extract Preserves Mitochondrial Function and Insulin Sensitivity by Attenuating Inflammation between Macrophages and Adipocytes In Vitro. Molecular nutrition & food research. 2019 05; 63(10):e1801413. doi: 10.1002/mnfr.201801413. [PMID: 31018035]
  • Ya-Wei Xing, Guang-Tao Lei, Qing-Hua Wu, Yu Jiang, Man-Xiang Huang. Procyanidin B2 protects against diet-induced obesity and non-alcoholic fatty liver disease via the modulation of the gut microbiota in rabbits. World journal of gastroenterology. 2019 Feb; 25(8):955-966. doi: 10.3748/wjg.v25.i8.955. [PMID: 30833801]
  • Eduardo Sommella, Nadia Badolati, Gennaro Riccio, Emanuela Salviati, Sara Bottone, Monica Dentice, Pietro Campiglia, Gian Carlo Tenore, Mariano Stornaiuolo, Ettore Novellino. A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells. Nutrients. 2019 Jan; 11(1):. doi: 10.3390/nu11010163. [PMID: 30646510]
  • Joanna Oracz, Ewa Nebesny, Dorota Żyżelewicz. Identification and quantification of free and bound phenolic compounds contained in the high-molecular weight melanoidin fractions derived from two different types of cocoa beans by UHPLC-DAD-ESI-HR-MSn. Food research international (Ottawa, Ont.). 2019 01; 115(?):135-149. doi: 10.1016/j.foodres.2018.08.028. [PMID: 30599925]
  • Nicola Busatto, Daiki Matsumoto, Alice Tadiello, Urska Vrhovsek, Fabrizio Costa. Multifaceted analyses disclose the role of fruit size and skin-russeting in the accumulation pattern of phenolic compounds in apple. PloS one. 2019; 14(7):e0219354. doi: 10.1371/journal.pone.0219354. [PMID: 31306452]
  • Dan Liu, Jianjun Deng, Snehal Joshi, Pengbo Liu, Chao Zhang, Yan Yu, Ruijuan Zhang, Daidi Fan, Haixia Yang, Doris H D'Souza. Monomeric catechin and dimeric procyanidin B2 against human norovirus surrogates and their physicochemical interactions. Food microbiology. 2018 Dec; 76(?):346-353. doi: 10.1016/j.fm.2018.06.009. [PMID: 30166160]
  • Nadia Badolati, Eduardo Sommella, Gennaro Riccio, Emanuela Salviati, Dimitri Heintz, Sara Bottone, Emery Di Cicco, Monica Dentice, Giancarlo Tenore, Pietro Campiglia, Mariano Stornaiuolo, Ettore Novellino. Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation. Nutrients. 2018 Oct; 10(10):. doi: 10.3390/nu10101406. [PMID: 30279339]
  • Hongming Su, Yuting Li, Dongwen Hu, Lianghua Xie, Huihui Ke, Xiaodong Zheng, Wei Chen. Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state. Free radical biology & medicine. 2018 10; 126(?):269-286. doi: 10.1016/j.freeradbiomed.2018.08.024. [PMID: 30142454]
  • Mei Deng, Yuanyuan Deng, Lihong Dong, Yongxuan Ma, Lei Liu, Fei Huang, Zhencheng Wei, Yan Zhang, Mingwei Zhang, Ruifen Zhang. Effect of Storage Conditions on Phenolic Profiles and Antioxidant Activity of Litchi Pericarp. Molecules (Basel, Switzerland). 2018 Sep; 23(9):. doi: 10.3390/molecules23092276. [PMID: 30200581]
  • Ying Xiao, Jialin Dong, Zhiting Yin, Qiguo Wu, Yiming Zhou, Xiaoli Zhou. Procyanidin B2 protects against d-galactose-induced mimetic aging in mice: Metabolites and microbiome analysis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018 Sep; 119(?):141-149. doi: 10.1016/j.fct.2018.05.017. [PMID: 29751077]
  • Junhui He, Mingchong Sun, Sujian Tian. Procyanidin B2 prevents lupus nephritis development in mice by inhibiting NLRP3 inflammasome activation. Innate immunity. 2018 07; 24(5):307-315. doi: 10.1177/1753425918780985. [PMID: 29874961]
  • Srividya Gopalakrishnan, Harshavardhana H Ediga, S Sreenivasa Reddy, G Bhanuprakash Reddy, Ayesha Ismail. Procyanidin-B2 enriched fraction of cinnamon acts as a proteasome inhibitor and anti-proliferative agent in human prostate cancer cells. IUBMB life. 2018 05; 70(5):445-457. doi: 10.1002/iub.1735. [PMID: 29537730]
  • Juan Vallejo-Ochoa, Mariel López-Marmolejo, Alma Alejandra Hernández-Esquivel, Manuel Méndez-Gómez, Laura Nicolasa Suárez-Soria, Elda Castro-Mercado, Ernesto García-Pineda. Early plant growth and biochemical responses induced by Azospirillum brasilense Sp245 lipopolysaccharides in wheat (Triticum aestivum L.) seedlings are attenuated by procyanidin B2. Protoplasma. 2018 Mar; 255(2):685-694. doi: 10.1007/s00709-017-1180-2. [PMID: 29110138]
  • Wei Wang, Renzong Chen, Jiye Wang. Procyanidin B2 ameliorates carrageenan-induced chronic nonbacterial prostatitis in rats via anti-inflammatory and activation of the Nrf2 pathway. Biochemical and biophysical research communications. 2017 11; 493(1):794-799. doi: 10.1016/j.bbrc.2017.08.089. [PMID: 28844677]
  • Yanfen Chen, Huanqing Li, Shu Zhang, Chaoyan Yang, Ziying Mai, Xueyan Hu, Zhenhu Gao, Hong Deng. Anti-myocardial Ischemia Effect and Components of Litchi Pericarp Extracts. Phytotherapy research : PTR. 2017 Sep; 31(9):1384-1391. doi: 10.1002/ptr.5865. [PMID: 28744920]
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