3-(3-hydroxyphenyl)propionate (BioDeep_00000003202)

 

Secondary id: BioDeep_00000867194, BioDeep_00001871802

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


dihydro-3-Coumaric acid, monosodium salt

化学式: C9H10O3 (166.062991)
中文名称: 3-(3-羟基苯基)丙酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.09%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

3-(3-hydroxyphenyl)propionate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/3-(3-hydroxyphenyl)propionate (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000003202). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC(=CC(=C1)O)CCC(=O)O
InChI: InChI=1S/C9H10O3/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-3,6,10H,4-5H2,(H,11,12)

描述信息

3-(3-Hydroxyphenyl)propanoic (hMPP) acid is one of the major metabolites of ingested caffeic acid (PMID: 15479001) and of the phenolic degradation products of proanthocyanidins (the most abundant polyphenol present in chocolate) by the microflora in the colon (PMID: 12663291). mHPP is suspected to have antioxidants properties and is actively absorbed by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers (PMID: 15479001, 12663291). hMPP has been found to be a metabolite of Clostridium, Escherichia, and Eubacterium (PMID: 28393285, 19520845). 3-(3-Hydroxyphenyl)propanoic acid is a flavonoid metabolite. 3-(3-Hydroxyphenyl)propanoic acid is a phenolic acid metabolite formed by the gut microflora detected after the consumption of whole grain.
3-(3-Hydroxyphenyl)propanoic (hMPP) acid is one of the major metabolites of ingested caffeic acid (PMID 15479001) and of the phenolic degradation products of proanthocyanidins (the most abundant polyphenol present in chocolate) by the microflora in the colon (PMID 12663291). mHPP is suspected to have antioxidants properties and is actively absorbed by the monocarboxylic acid transporter (MCT) in intestinal Caco-2 cell monolayers (PMID 15479001, 12663291). [HMDB]
3-(3-Hydroxyphenyl)propionic acid is a flavonoid metabolite formed by human microflora. 3-(3-Hydroxyphenyl)propionic acid shows vasodilatory activity[1].
3-(3-Hydroxyphenyl)propionic acid is a flavonoid metabolite formed by human microflora. 3-(3-Hydroxyphenyl)propionic acid shows vasodilatory activity[1].

同义名列表

39 个代谢物同义名

dihydro-3-Coumaric acid, monosodium salt; beta-(m-Hydroxyphenyl)propionic acid; beta-(3-Hydroxyphenyl)propionic acid; 3-(3-Hydroxy-phenyl)-propanoic acid; 3-(3-Hydroxy-phenyl)-propionic acid; 3-(3-hydroxyphenyl)propanoic acid; 3-(3-Hydroxyphenyl)propionic acid; 3-(3-Hydroxyphenyl)propanoic acid; 3-(m-Hydroxyphenyl)propionic acid; Β-(m-hydroxyphenyl)propionic acid; b-(m-Hydroxyphenyl)propionic acid; b-(3-Hydroxyphenyl)propionic acid; beta-(3-Hydroxyphenyl)propionate; beta-(m-Hydroxyphenyl)propionate; 3-(3-Hydroxy-phenyl)-propanoate; 3-Hydroxybenzenepropanoic acid; 3-Hydroxydihydrocinnamic acid; 3-(3-Hydroxyphenyl)propanoate; m-Hydroxyphenylpropionic acid; b-(m-Hydroxyphenyl)propionate; 3-(3-Hydroxyphenyl)propionate; b-(3-Hydroxyphenyl)propionate; 3-Hydroxyphenylpropanoic acid; Β-(m-hydroxyphenyl)propionate; 3-Hydroxyphenylpropionic acid; 3-(m-Hydroxyphenyl)propionate; m-Hydroxy-hydrocinnamic acid; 3-Hydroxyhydrocinnamic acid; 3-Hydroxybenzenepropanoate; m-Hydroxyphenylpropionate; 3-Hydroxyphenylpropanoate; 3-Hydroxydihydrocinnamate; 3-Hydroxyphenylpropionate; m-Hydroxy-hydrocinnamate; dihydro-m-Coumaric acid; Dihydro-3-coumaric acid; m-Hydrocoumaric acid; dihydro-m-Coumarate; Dihydro-3-coumarate



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

5 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(4)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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  • Gary Williamson, Michael N Clifford. Colonic metabolites of berry polyphenols: the missing link to biological activity?. The British journal of nutrition. 2010 Oct; 104 Suppl 3(?):S48-66. doi: 10.1017/s0007114510003946. [PMID: 20955650]
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  • Jun-Fang Wu, Elaine Holmes, Jian Xue, Shu-Hua Xiao, Burton H Singer, Hui-Ru Tang, Jürg Utzinger, Yu-Lan Wang. Metabolic alterations in the hamster co-infected with Schistosoma japonicum and Necator americanus. International journal for parasitology. 2010 May; 40(6):695-703. doi: 10.1016/j.ijpara.2009.11.003. [PMID: 19951707]
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  • Ronald L Prior, Theodore R Rogers, Ramesh C Khanal, Samuel E Wilkes, Xianli Wu, Luke R Howard. Urinary excretion of phenolic acids in rats fed cranberry. Journal of agricultural and food chemistry. 2010 Apr; 58(7):3940-9. doi: 10.1021/jf9028392. [PMID: 20052972]
  • Sonia de Pascual-Teresa, Diego A Moreno, Cristina García-Viguera. Flavanols and anthocyanins in cardiovascular health: a review of current evidence. International journal of molecular sciences. 2010 Apr; 11(4):1679-703. doi: 10.3390/ijms11041679. [PMID: 20480037]
  • Kennan Kellaris Salinero, Keith Keller, William S Feil, Helene Feil, Stephan Trong, Genevieve Di Bartolo, Alla Lapidus. Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation. BMC genomics. 2009 Aug; 10(?):351. doi: 10.1186/1471-2164-10-351. [PMID: 19650930]
  • Maaike M Appeldoorn, Jean-Paul Vincken, Anna-Marja Aura, Peter C H Hollman, Harry Gruppen. Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-gamma-valerolactone as the major metabolites. Journal of agricultural and food chemistry. 2009 Feb; 57(3):1084-92. doi: 10.1021/jf803059z. [PMID: 19191673]
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  • Natalie C Ward, Kevin D Croft, Ian B Puddey, Jonathan M Hodgson. Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic Acid, an important metabolite of proanthocyanidins in humans. Journal of agricultural and food chemistry. 2004 Aug; 52(17):5545-9. doi: 10.1021/jf049404r. [PMID: 15315398]
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