Pirinixic acid (BioDeep_00000002328)

   

human metabolite blood metabolite


代谢物信息卡片


2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid

化学式: C14H14ClN3O2S (323.0495)
中文名称: [4-氯-6-(2,3-茬胺基)-2-嘧啶硫代]乙酸
谱图信息: 最多检出来源 Mus musculus(plant) 8.94%

分子结构信息

SMILES: CC1=C(C)C(NC2=CC(Cl)=NC(SCC(O)=O)=N2)=CC=C1
InChI: InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18)

描述信息

2-methylthioribosyl-trans-zeatin, also known as wy-14,643 or cxpta, is a member of the class of compounds known as aryl thioethers. Aryl thioethers are organosulfur compounds containing a thioether group that is substituted by an aryl group. 2-methylthioribosyl-trans-zeatin is practically insoluble (in water) and a weakly acidic compound (based on its pKa). 2-methylthioribosyl-trans-zeatin can be found in common pea and common wheat, which makes 2-methylthioribosyl-trans-zeatin a potential biomarker for the consumption of these food products.
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9387; ORIGINAL_PRECURSOR_SCAN_NO 9382
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9350; ORIGINAL_PRECURSOR_SCAN_NO 9349
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4901; ORIGINAL_PRECURSOR_SCAN_NO 4897
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4896; ORIGINAL_PRECURSOR_SCAN_NO 4894
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9397; ORIGINAL_PRECURSOR_SCAN_NO 9396
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4984; ORIGINAL_PRECURSOR_SCAN_NO 4982
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9362; ORIGINAL_PRECURSOR_SCAN_NO 9360
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9288; ORIGINAL_PRECURSOR_SCAN_NO 9287
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4364; ORIGINAL_PRECURSOR_SCAN_NO 4363
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9321; ORIGINAL_PRECURSOR_SCAN_NO 9318
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4386; ORIGINAL_PRECURSOR_SCAN_NO 4382
CONFIDENCE standard compound; INTERNAL_ID 293; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4906; ORIGINAL_PRECURSOR_SCAN_NO 4904
Pirinixic acid (Wy-14643) is a potent agonist of PPARα, with EC50s of 0.63 μM, 32 μM for murine PPARα and PPARγ, and 5.0 μM, 60 μM, 35 μM for human PPARα, PPARγ and PPARδ, respectively.

同义名列表

18 个代谢物同义名

2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid; ((4-Chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio)acetic acid; ((4-Chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio)acetate; 4-Chloro-6-(2,3-dimethylphenyl)amino-2-pyrimidinylthioacetic acid; (4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio)acetic acid; 4-Chloro-6-(2,3-xylidinyl)-2-pyrimidinylthioacetic acid; (4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio)acetate; 2-Methylthioribosyl-trans-zeatin; Pirinixic acid; Wyeth 14,643; Wyeth-14643; Pirinixate; WY-14,643; CXPTA; [[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-acetic acid; Wy-14643; Wy 14643; Pirinixic acid



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 AKT1, ALOX5, CAT, MAPK14, MAPK8, NFKB1, PIK3C3, PPARG
Peripheral membrane protein 2 ALOX5, CRAT
Endoplasmic reticulum membrane 1 PTGES
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 8 AKT1, MAPK14, MAPK8, NFKB1, PCNA, PPARA, PPARG, PPARGC1A
autophagosome 1 PIK3C3
cytosol 13 ACOX1, AKT1, ALOX5, CAT, CRAT, GPT, MAPK14, MAPK8, NFKB1, PIK3C3, PPARG, PPARGC1A, PRKCQ
nuclear body 1 PCNA
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 1 PCNA
nucleoplasm 9 AKT1, ALOX5, MAPK14, MAPK8, NFKB1, PCNA, PPARA, PPARG, PPARGC1A
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 2 AKT1, TNF
lamellipodium 1 AKT1
Multi-pass membrane protein 2 PTGES, UCP3
Synapse 1 MAPK8
cell cortex 1 AKT1
cell surface 1 TNF
glutamatergic synapse 3 AKT1, MAPK14, PIK3C3
Golgi membrane 1 INS
mitochondrial inner membrane 2 CRAT, UCP3
neuronal cell body 1 TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 1 ALOX5
endosome 1 PIK3C3
plasma membrane 3 AKT1, PRKCQ, TNF
Membrane 5 ACOX1, AKT1, CAT, PIK3C3, PTGES
axon 1 MAPK8
extracellular exosome 3 CAT, GPT, PCNA
endoplasmic reticulum 1 CRAT
extracellular space 4 ALOX5, IL6, INS, TNF
perinuclear region of cytoplasm 3 ALOX5, PPARG, PTGES
mitochondrion 5 CAT, CRAT, MAPK14, NFKB1, UCP3
protein-containing complex 2 AKT1, CAT
intracellular membrane-bounded organelle 2 CAT, PPARG
Secreted 2 IL6, INS
extracellular region 7 ALOX5, CAT, IL6, INS, MAPK14, NFKB1, TNF
mitochondrial matrix 1 CAT
transcription regulator complex 1 NFKB1
centriolar satellite 1 PRKCQ
Nucleus membrane 1 ALOX5
nuclear membrane 1 ALOX5
external side of plasma membrane 1 TNF
microtubule cytoskeleton 1 AKT1
midbody 1 PIK3C3
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cytoplasm, perinuclear region 2 ALOX5, PTGES
Mitochondrion inner membrane 2 CRAT, UCP3
Matrix side 1 CRAT
Membrane raft 1 TNF
focal adhesion 1 CAT
spindle 1 AKT1
GABA-ergic synapse 1 PIK3C3
Peroxisome 4 ACOX1, CAT, CRAT, PIK3C3
Peroxisome matrix 1 CAT
peroxisomal matrix 3 ACOX1, CAT, CRAT
peroxisomal membrane 2 ACOX1, CAT
Nucleus, PML body 1 PPARGC1A
PML body 1 PPARGC1A
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
axoneme 1 PIK3C3
nuclear speck 1 MAPK14
Late endosome 1 PIK3C3
receptor complex 1 PPARG
ciliary basal body 1 AKT1
chromatin 5 NFKB1, PCNA, PPARA, PPARG, PPARGC1A
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
[Isoform 1]: Mitochondrion 1 CRAT
spindle pole 1 MAPK14
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
endosome lumen 1 INS
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
replication fork 1 PCNA
ficolin-1-rich granule lumen 3 ALOX5, CAT, MAPK14
secretory granule lumen 5 ALOX5, CAT, INS, MAPK14, NFKB1
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 IL6, INS
nuclear matrix 1 ALOX5
male germ cell nucleus 1 PCNA
specific granule lumen 1 NFKB1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
presynaptic endosome 1 PIK3C3
aggresome 1 PRKCQ
Nucleus matrix 1 ALOX5
nuclear envelope lumen 2 ALOX5, PTGES
nuclear lamina 1 PCNA
[Isoform 1]: Nucleus 1 PPARGC1A
basal dendrite 1 MAPK8
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
postsynaptic endosome 1 PIK3C3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Autolysosome 1 PIK3C3
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
Nucleus intermembrane space 1 ALOX5
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
[Nuclear factor NF-kappa-B p105 subunit]: Cytoplasm 1 NFKB1
[Nuclear factor NF-kappa-B p50 subunit]: Nucleus 1 NFKB1
I-kappaB/NF-kappaB complex 1 NFKB1
NF-kappaB p50/p65 complex 1 NFKB1
[Isoform 2]: Peroxisome 1 CRAT
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[Isoform B4]: Nucleus 1 PPARGC1A
[Isoform B4-8a]: Cytoplasm 1 PPARGC1A
[Isoform B5]: Nucleus 1 PPARGC1A
[Isoform 9]: Nucleus 1 PPARGC1A


文献列表

  • G De Soricellis, F Rinaldi, S Tengattini, C Temporini, S Negri, D Capelli, R Montanari, H Cena, S Salerno, G Massolini, F Guzzo, E Calleri. Development of an analytical platform for the affinity screening of natural extracts by SEC-MS towards PPARα and PPARγ receptors. Analytica chimica acta. 2024 Jun; 1309(?):342666. doi: 10.1016/j.aca.2024.342666. [PMID: 38772654]
  • Chen Cao, Qingyuan Yang, Xiaoshuang Xia, Zhuangzhuang Chen, Peilin Liu, Xiaowen Wu, Hu Hu, Zhongren Ding, Xin Li. WY-14643, a novel antiplatelet and antithrombotic agent targeting the GPIbα receptor. Thrombosis research. 2024 Jun; 238(?):41-51. doi: 10.1016/j.thromres.2024.04.011. [PMID: 38669962]
  • Donghwan Kim, Sang Keun Ha, Frank J Gonzalez. CBFA2T3 Is PPARA Sensitive and Attenuates Fasting-Induced Lipid Accumulation in Mouse Liver. Cells. 2024 May; 13(10):. doi: 10.3390/cells13100831. [PMID: 38786053]
  • Yong Fan, Jing Lu, Jinghui Fan, Shuang Guan. 1,3-dichloro-2-propanol caused lipid droplets accumulation by suppressing neutral lipases via BMAL1 in hepatocytes. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Feb; 174(?):113670. doi: 10.1016/j.fct.2023.113670. [PMID: 36805544]
  • Jie Yang, Shicheng Fan, Yifei Zhang, Min Huang, Yue Gao, Huichang Bi. Chronic Treatment With WY-14643 Induces Tumorigenesis and Triglyceride Accumulation in Mouse Livers. Drug metabolism and disposition: the biological fate of chemicals. 2022 12; 50(12):1464-1471. doi: 10.1124/dmd.122.000908. [PMID: 36184081]
  • Rui Wang, Jun Zhao, Jiacheng Jin, Yun Tian, Lan Lan, Xuejian Wang, Liang Zhu, Jianbo Wang. WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC. Lipids in health and disease. 2022 Nov; 21(1):121. doi: 10.1186/s12944-022-01726-7. [PMID: 36384580]
  • Yunhui Xu, Krista L Denning, Yongke Lu. PPARα agonist WY-14,643 induces the PLA2/COX-2/ACOX1 pathway to enhance peroxisomal lipid metabolism and ameliorate alcoholic fatty liver in mice. Biochemical and biophysical research communications. 2022 07; 613(?):47-52. doi: 10.1016/j.bbrc.2022.04.132. [PMID: 35526488]
  • Sabina Sblano, Carmen Cerchia, Antonio Laghezza, Luca Piemontese, Leonardo Brunetti, Rosalba Leuci, Federica Gilardi, Aurelien Thomas, Massimo Genovese, Alice Santi, Paolo Tortorella, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice. A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity. European journal of medicinal chemistry. 2022 May; 235(?):114240. doi: 10.1016/j.ejmech.2022.114240. [PMID: 35325635]
  • Cigdem Sahin, Lilia Magomedova, Thais A M Ferreira, Jiabao Liu, Jens Tiefenbach, Priscilla S Alves, Fellipe J G Queiroz, Andressa S de Oliveira, Mousumi Bhattacharyya, Julie Grouleff, Patrícia C N Nogueira, Edilberto R Silveira, Daniel C Moreira, José Roberto Souza de Almeida Leite, Guilherme D Brand, David Uehling, Gennady Poda, Henry Krause, Carolyn L Cummins, Luiz A S Romeiro. Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases. Journal of medicinal chemistry. 2022 02; 65(3):1961-1978. doi: 10.1021/acs.jmedchem.1c01542. [PMID: 35089724]
  • Shicheng Fan, Yue Gao, Aijuan Qu, Yiming Jiang, Hua Li, Guomin Xie, Xinpeng Yao, Xiao Yang, Shuguang Zhu, Tomoki Yagai, Jianing Tian, Ruimin Wang, Frank J Gonzalez, Min Huang, Huichang Bi. YAP-TEAD mediates PPAR α-induced hepatomegaly and liver regeneration in mice. Hepatology (Baltimore, Md.). 2022 01; 75(1):74-88. doi: 10.1002/hep.32105. [PMID: 34387904]
  • Yunhui Xu, Krista L Denning, Yongke Lu. PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1. Biochemical pharmacology. 2021 10; 192(?):114678. doi: 10.1016/j.bcp.2021.114678. [PMID: 34265279]
  • Xue Chen, Yunhui Xu, Krista L Denning, Audrey Grigore, Yongke Lu. PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase. Free radical biology & medicine. 2021 06; 169(?):283-293. doi: 10.1016/j.freeradbiomed.2021.04.018. [PMID: 33892114]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Guozhu Ye, Bi-Cheng Yang, Han Gao, Zeming Wu, Jinsheng Chen, Xiao-Yan Ai, Qiansheng Huang. Metabolomics Insights into Oleate-Induced Disorders of Phospholipid Metabolism in Macrophages. The Journal of nutrition. 2021 03; 151(3):503-512. doi: 10.1093/jn/nxaa411. [PMID: 33571370]
  • Yu Yang, Yu Zhao, Wenzhen Li, Yuyao Wu, Xin Wang, Yijie Wang, Tingmei Liu, Tinghong Ye, Yongmei Xie, Zhiqiang Cheng, Jun He, Peng Bai, Yiwen Zhang, Liang Ouyang. Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment. European journal of medicinal chemistry. 2020 Jul; 197(?):112311. doi: 10.1016/j.ejmech.2020.112311. [PMID: 32339855]
  • Yanfeng Xue, Changzheng Guo, Fan Hu, Weiyun Zhu, Shengyong Mao. PPARA/RXRA signalling regulates the fate of hepatic non-esterified fatty acids in a sheep model of maternal undernutrition. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2020 02; 1865(2):158548. doi: 10.1016/j.bbalip.2019.158548. [PMID: 31676441]
  • Yumiko Mizukawa, Yoko Amagase, Tetsuro Urushidani. Extraction of peroxisome proliferator-activated receptor α agonist-induced lipid metabolism-related and unrelated genes in rat liver and analysis of their genomic location. The Journal of toxicological sciences. 2020; 45(8):449-473. doi: 10.2131/jts.45.449. [PMID: 32741897]
  • Lujin Wu, Wei Wang, Meiyan Dai, Huihui Li, Chen Chen, Daowen Wang. PPARα ligand, AVE8134, and cyclooxygenase inhibitor therapy synergistically suppress lung cancer growth and metastasis. BMC cancer. 2019 Dec; 19(1):1166. doi: 10.1186/s12885-019-6379-5. [PMID: 31791289]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
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  • Almudena Bermejo, Aida Collado, Isabel Barrachina, Patrice Marqués, Noureddine El Aouad, Xavier Franck, Francisco Garibotto, Catherine Dacquet, Daniel H Caignard, Fernando D Suvire, Ricardo D Enriz, Laura Piqueras, Bruno Figadère, María-Jesús Sanz, Nuria Cabedo, Diego Cortes. Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγ Agonist Activity and Anti-inflammatory Effect. Journal of natural products. 2019 07; 82(7):1802-1812. doi: 10.1021/acs.jnatprod.9b00003. [PMID: 31268307]
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  • Sae On Kim, Yujia Han, Sungjin Ahn, Seungchan An, Jeayoung C Shin, Hyunjung Choi, Hyoung-June Kim, Nok Hyun Park, Yong-Jin Kim, Sun Hee Jin, Ho Sik Rho, Minsoo Noh. Kojyl cinnamate esters are peroxisome proliferator-activated receptor α/γ dual agonists. Bioorganic & medicinal chemistry. 2018 11; 26(21):5654-5663. doi: 10.1016/j.bmc.2018.10.010. [PMID: 30352713]
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