(E)-Monocrotophos (BioDeep_00000002080)

 

Secondary id: BioDeep_00000403345

human metabolite Endogenous


代谢物信息卡片


Phosphoric acid, dimethyl (e)-1-methyl-3-(methylamino)-3-oxo-1-propenyl ester

化学式: C7H14NO5P (223.061)
中文名称: 久效磷
谱图信息: 最多检出来源 Homo sapiens(natural_products) 25%

分子结构信息

SMILES: C/C(=C\C(=N\C)\O)/OP(=O)(OC)OC
InChI: InChI=1S/C7H14NO5P/c1-6(5-7(9)8-2)13-14(10,11-3)12-4/h5H,1-4H3,(H,8,9)/b6-5+

描述信息

(e)-monocrotophos, also known as azodrin or dimethyl (E)-3-hydroxy-N-methylcrotonamide, is a member of the class of compounds known as dialkyl phosphates. Dialkyl phosphates are organic compounds containing a phosphate group that is linked to exactly two alkyl chain (e)-monocrotophos is slightly soluble (in water) and an extremely weak acidic compound (based on its pKa). Within the cell, (e)-monocrotophos is primarily located in the cytoplasm. It can also be found in the extracellular space (e)-monocrotophos is a non-carcinogenic (not listed by IARC) potentially toxic compound. If the compound has been ingested, rapid gastric lavage should be performed using 5\\% sodium bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered the eyes, they should be washed with large quantities of isotonic saline or water. In serious cases, atropine and/or pralidoxime should be administered. Anti-cholinergic drugs work to counteract the effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in conjunction with pralidoxime or other pyridinium oximes (such as trimedoxime or obidoxime), though the use of -oximes has been found to be of no benefit, or possibly harmful, in at least two meta-analyses. Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally (T3DB).
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
(E)-Monocrotophos is an Agricultural insecticide with both systemic and contact actio
D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
CONFIDENCE standard compound; INTERNAL_ID 3133
D010575 - Pesticides > D007306 - Insecticides
D009676 - Noxae > D009153 - Mutagens
D016573 - Agrochemicals

同义名列表

61 个代谢物同义名

Phosphoric acid, dimethyl (e)-1-methyl-3-(methylamino)-3-oxo-1-propenyl ester; Phosphate, dimethyl (e)-1-methyl-3-(methylamino)-3-oxo-1-propenyl ester; Dimethyl (e)-1-methyl-2-(methylcarbamoyl)vinyl phosphoric acid; O,O-Dimethyl-O-(2-N-methylcarbamoyl-1-methyl-vinyl)-fosfaat; 3-Hydroxy-N-methyl-cis-crotonamide dimethyl phosphate ester; Dimethyl 1-methyl-2-(methylcarbamoyl)vinyl phosphate, cis; O,O-Dimethyl cis-1-methyl-2-methylcarbamoylvinylphosphate; O,O-Dimetil-O-(2-N-metilcarbamoil-1-metil-vinil)-fosfato; Dimethyl phosphate OF 3-hydroxy-N-methyl-cis-crotonamide; Dimethyl (e)-1-methyl-2-(methylcarbamoyl)vinyl phosphate; (2E)-3-[(dimethoxyphosphoryl)oxy]-N-methylbut-2-enamide; 3-Hydroxy-N-methyl-cis-crotonamide dimethyl phosphate; 3-Hydroxy-N-methyl-dimethylphosphate(e)-crotonamide; 3-Hydroxy-N-methyl-dimethylphosphatecis-crotonamide; 3-(Dimethoxyphosphinyloxy)N-methyl-cis-crotonamide; 3-Dimethoxyphosphinoyloxy-N-methylisocrotonamide; cis-1-Methyl-2-methyl carbamoyl vinyl phosphate; Dimethyl (e)-3-hydroxy-N-methylcrotonamide; Des-N-methyl dicrotophos; Monocrotophos 40 ec; Azodrin insecticide; N-Desmethyl bidrin; (E)-Monocrotophos; e-Monocrotophos; Monokrotofosz; Glore phos 36; MONOCROTOPHOS; Shell SD 9129; Azodrin 202R; Nuvacron 20; Nuvacron-20; Azodrin-71; Pillardrin; Monocil 40; Plantdrin; Croton 36; Crisodrin; Crisodin; Nuvacron; Biloborn; Bilobran; Momordin; Monostar; Corophos; Parryfos; Monodrin; Monocron; Hazodrin; Aimocron; Apadrin; Rapid X; Monocil; Alphate; Azodrin; Azadrin; Susvin; Crotos; Pandar; Ulvair; Monocrotophos; Monocrotophos



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ARHGAP45, CASP3, CASP9, CAT, CYP1A1, FASN, FLNA, HPGDS, NFE2L2, TH
Peripheral membrane protein 2 ACHE, CYP1A1
Endoplasmic reticulum membrane 3 CYP19A1, CYP1A1, STAR
Nucleus 8 ACHE, CASP3, CASP9, FLNA, NFE2L2, NR1I2, PPARGC1A, TH
cytosol 12 ARHGAP45, CASP3, CASP9, CAT, FASN, FLNA, GSR, HPGDS, NFE2L2, PPARGC1A, TAT, TH
dendrite 1 TH
nuclear body 1 NR1I2
trans-Golgi network 1 FLNA
centrosome 1 NFE2L2
nucleoplasm 6 ATP2B1, CASP3, HPGDS, NFE2L2, NR1I2, PPARGC1A
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 3 ACHE, ATP2B1, STAR
ruffle membrane 1 ARHGAP45
Cell projection, axon 1 TH
Cell projection, growth cone 1 FLNA
Multi-pass membrane protein 2 ATP2B1, CYP19A1
Synapse 2 ACHE, ATP2B1
cell surface 1 ACHE
dendritic shaft 1 FLNA
glutamatergic synapse 3 ATP2B1, CASP3, FLNA
Golgi apparatus 3 ACHE, FASN, NFE2L2
Golgi membrane 1 INS
mitochondrial inner membrane 1 CYP1A1
neuromuscular junction 1 ACHE
neuronal cell body 1 CASP3
postsynapse 1 FLNA
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 1 TH
synaptic vesicle 1 TH
Cytoplasm, cytosol 1 NFE2L2
plasma membrane 8 ACHE, ARHGAP45, ATP2B1, BCHE, FASN, FLNA, NFE2L2, STAR
synaptic vesicle membrane 1 ATP2B1
terminal bouton 1 TH
Membrane 7 ACHE, ARHGAP45, ATP2B1, CAT, CYP19A1, FASN, FLNA
axon 1 TH
basolateral plasma membrane 1 ATP2B1
brush border 1 FLNA
extracellular exosome 5 ATP2B1, CAT, FASN, FLNA, GSR
endoplasmic reticulum 1 CYP19A1
extracellular space 3 ACHE, BCHE, INS
perinuclear region of cytoplasm 3 ACHE, FLNA, TH
mitochondrion 6 CASP9, CAT, CYP1A1, GSR, STAR, TH
protein-containing complex 2 CASP9, CAT
intracellular membrane-bounded organelle 4 ATP2B1, CAT, CYP1A1, HPGDS
Microsome membrane 2 CYP19A1, CYP1A1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 STAR
Secreted 3 ACHE, BCHE, INS
extracellular region 6 ACHE, ARHGAP45, BCHE, CAT, FLNA, INS
cytoplasmic side of plasma membrane 1 TH
mitochondrial matrix 3 CAT, GSR, STAR
Extracellular side 1 ACHE
transcription regulator complex 1 NR1I2
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 1 GSR
actin cytoskeleton 1 FLNA
perikaryon 2 FLNA, TH
Z disc 1 FLNA
cytoplasmic vesicle 1 TH
nucleolus 1 FLNA
Melanosome membrane 1 TH
cell-cell junction 1 FLNA
Cell projection, ruffle membrane 1 ARHGAP45
Cytoplasm, perinuclear region 1 TH
Mitochondrion inner membrane 1 CYP1A1
Cytoplasm, cytoskeleton 1 FLNA
focal adhesion 2 CAT, FLNA
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 PPARGC1A
PML body 1 PPARGC1A
mitochondrial intermembrane space 1 STAR
lateral plasma membrane 1 ATP2B1
neuron projection 1 TH
chromatin 3 NFE2L2, NR1I2, PPARGC1A
mediator complex 1 NFE2L2
axonal growth cone 1 FLNA
cell projection 1 ATP2B1
Cell projection, podosome 1 FLNA
podosome 1 FLNA
Cytoplasm, cell cortex 1 FLNA
actin filament 1 FLNA
blood microparticle 1 BCHE
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
endosome lumen 1 INS
Melanosome 1 FASN
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
intermediate filament cytoskeleton 1 NR1I2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 ARHGAP45, CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 BCHE, INS
transport vesicle 1 INS
azurophil granule lumen 1 ARHGAP45
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
nuclear envelope lumen 1 BCHE
apoptosome 1 CASP9
[Isoform 1]: Nucleus 1 PPARGC1A
synaptic cleft 1 ACHE
protein-DNA complex 1 NFE2L2
apical dendrite 1 FLNA
death-inducing signaling complex 1 CASP3
intracellular non-membrane-bounded organelle 1 FLNA
actin filament bundle 1 FLNA
cortical cytoskeleton 1 FLNA
catalase complex 1 CAT
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle 1 TH
glycoprotein Ib-IX-V complex 1 FLNA
Myb complex 1 FLNA
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE
glycogen granule 1 FASN
caspase complex 1 CASP9
[Isoform B4]: Nucleus 1 PPARGC1A
[Isoform B4-8a]: Cytoplasm 1 PPARGC1A
[Isoform B5]: Nucleus 1 PPARGC1A
[Isoform 9]: Nucleus 1 PPARGC1A


文献列表

  • Shazmin, Siti Aqlima Ahmad, Tatheer Alam Naqvi, Muhammad Farooq Hussain Munis, Muhammad Tariq Javed, Hassan Javed Chaudhary. Biodegradation of monocrotophos by Brucella intermedia Msd2 isolated from cotton plant. World journal of microbiology & biotechnology. 2023 Mar; 39(6):141. doi: 10.1007/s11274-023-03575-7. [PMID: 37000294]
  • Mary Isabella Sonali J, K Veena Gayathri, P Senthil Kumar, Gayathri Rangasamy. A study of potent biofertiliser and its degradation ability of monocrotophos and its in silico analysis. Chemosphere. 2023 Jan; 312(Pt 2):137304. doi: 10.1016/j.chemosphere.2022.137304. [PMID: 36410511]
  • Twinkle Dhillon, Amit Kumar, Vijay Kumar. Neuroprotective Effect of N-acetylcysteine Against Monocrotophos-Induced Oxidative Stress in Different Brain Regions of Rats. Applied biochemistry and biotechnology. 2022 Sep; 194(9):4049-4065. doi: 10.1007/s12010-022-03967-9. [PMID: 35587328]
  • C S K Mishra, Suryasikha Samal, Rashmi Rekha Samal, Binayak Prasad Behera, Pragyan Pallavini, Priyadarshini Dash, Satyabrata Brahma, Tanushree Moharana, Stutiprgnya Pradhan, Pratik Acharya. Polyvinylchloride and polypropylene as adsorbents of the pesticide monocrotophos enhance oxidative stress in Eudrillus eugeniae (Kinberg). Chemosphere. 2022 May; 295(?):133837. doi: 10.1016/j.chemosphere.2022.133837. [PMID: 35120958]
  • Shaheen Jafri Ali. Monocrotophos, an organophosphorus insecticide, induces cortical and trabecular bone loss in Swiss albino mice. Chemico-biological interactions. 2020 Sep; 329(?):109112. doi: 10.1016/j.cbi.2020.109112. [PMID: 32360284]
  • R Nagaraju, Akr Joshi, S Vamadeva, P S Rajini. Effect of chronic exposure to monocrotophos on white adipose tissue in rats and its association with metabolic dyshomeostasis. Human & experimental toxicology. 2020 Sep; 39(9):1190-1199. doi: 10.1177/0960327120913080. [PMID: 32207356]
  • Raju Nagaraju, Apurva K R Joshi, Sowmya G Vamadeva, Padmanabhan S Rajini. Deregulation of hepatic lipid metabolism associated with insulin resistance in rats subjected to chronic monocrotophos exposure. Journal of biochemical and molecular toxicology. 2020 Aug; 34(8):e22506. doi: 10.1002/jbt.22506. [PMID: 32267039]
  • Perumal Vivekanandhan, Kannan Swathy, Dharman Kalaimurugan, Marimuthu Ramachandran, Ananthanarayanan Yuvaraj, Arjunan Naresh Kumar, Ayyavu Thendral Manikandan, Neelakandan Poovarasan, Muthugoundar Subramanian Shivakumar, Eliningaya J Kweka. Larvicidal toxicity of Metarhizium anisopliae metabolites against three mosquito species and non-targeting organisms. PloS one. 2020; 15(5):e0232172. doi: 10.1371/journal.pone.0232172. [PMID: 32365106]
  • Durgesh Kumar Jaiswal, Jay Prakash Verma, Ram Krishna, Anand Kumar Gaurav, Janardan Yadav. Molecular characterization of monocrotophos and chlorpyrifos tolerant bacterial strain for enhancing seed germination of vegetable crops. Chemosphere. 2019 May; 223(?):636-650. doi: 10.1016/j.chemosphere.2019.02.053. [PMID: 30798059]
  • Zou Bin, Chu Yanhong, Xia Jiaojiao, Yao Jing. Acetylcholinesterase biosensor based on functionalized surface of carbon nanotubes for monocrotophos detection. Analytical biochemistry. 2018 11; 560(?):12-18. doi: 10.1016/j.ab.2018.08.024. [PMID: 30172744]
  • Xiaona Zhang, Wei Liu, Jun Wang, Hua Tian, Wei Wang, Shaoguo Ru. Quantitative analysis of in-vivo responses of reproductive and thyroid endpoints in male goldfish exposed to monocrotophos pesticide. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2018 Sep; 211(?):41-47. doi: 10.1016/j.cbpc.2018.05.010. [PMID: 29803892]
  • Yun-Xiu Hou, Shi-Wen Liu, Lian-Wen Wang, Shu-Hua Wu. Physiopathology of multiple organ dysfunctions in severely monocrotophos-poisoned rabbits. Chemico-biological interactions. 2017 Dec; 278(?):9-14. doi: 10.1016/j.cbi.2017.08.016. [PMID: 28864276]
  • Xiaona Zhang, Shuman Li, Cuicui Wang, Hua Tian, Wei Wang, Shaoguo Ru. Effects of monocrotophos pesticide on cholinergic and dopaminergic neurotransmitter systems during early development in the sea urchin Hemicentrotus pulcherrimus. Toxicology and applied pharmacology. 2017 08; 328(?):46-53. doi: 10.1016/j.taap.2017.05.003. [PMID: 28479505]
  • Vinay Kumar Tripathi, Vivek Kumar, Ankita Pandey, Pankhi Vatsa, Anupam Dhasmana, Rajat Pratap Singh, Sri Hari Chandan Appikonda, Inho Hwang, Mohtashim Lohani. Monocrotophos Induces the Expression of Xenobiotic Metabolizing Cytochrome P450s (CYP2C8 and CYP3A4) and Neurotoxicity in Human Brain Cells. Molecular neurobiology. 2017 07; 54(5):3633-3651. doi: 10.1007/s12035-016-9938-7. [PMID: 27206429]
  • Hua Tian, Yang Sun, Hui Wang, Xin Bing, Wei Wang, Shaoguo Ru. Monocrotophos pesticide affects synthesis and conversion of sex steroids through multiple targets in male goldfish (Carassius auratus). Scientific reports. 2017 05; 7(1):2306. doi: 10.1038/s41598-017-01935-6. [PMID: 28536437]
  • Madhusudan Reddy Narra, Kodimyala Rajender, R Rudra Reddy, U Suryanarayana Murty, Ghousia Begum. Insecticides induced stress response and recuperation in fish: Biomarkers in blood and tissues related to oxidative damage. Chemosphere. 2017 Feb; 168(?):350-357. doi: 10.1016/j.chemosphere.2016.10.066. [PMID: 27810534]
  • S Binukumari, K Anusiya Devi, J Vasanthi. Applications in environmental risk assessment of biochemical analysis on the Indian fresh water fish, Labeo rohita exposed to monocrotophos pesticide. Environmental toxicology and pharmacology. 2016 Oct; 47(?):200-205. doi: 10.1016/j.etap.2016.08.014. [PMID: 27771501]
  • Shaheen Jafri Ali, Padmanabhan Sharda Rajini. Effect of monocrotophos, an organophosphorus insecticide, on the striatal dopaminergic system in a mouse model of Parkinson's disease. Toxicology and industrial health. 2016 Jul; 32(7):1153-65. doi: 10.1177/0748233714547733. [PMID: 25227224]
  • Xiaona Zhang, Yan Zhong, Hua Tian, Wei Wang, Shaoguo Ru. Impairment of the cortisol stress response mediated by the hypothalamus-pituitary-interrenal (HPI) axis in zebrafish (Danio rerio) exposed to monocrotophos pesticide. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2015 Oct; 176-177(?):10-6. doi: 10.1016/j.cbpc.2015.07.003. [PMID: 26196239]
  • Jun Wang, Wei Wang, Xiaona Zhang, Hua Tian, Shaoguo Ru. Development of a lipovitellin-based goldfish (Carassius auratus) vitellogenin ELISA for detection of environmental estrogens. Chemosphere. 2015 Aug; 132(?):166-71. doi: 10.1016/j.chemosphere.2015.03.038. [PMID: 25855009]
  • Ravneet Kaur Uppal, Mohinder Singh Johal, Madan Lal Sharma. Toxicological effects and recovery of the corneal epithelium in Cyprinus carpio communis Linn. exposed to monocrotophos: an scanning electron microscope study. Veterinary ophthalmology. 2015 May; 18(3):214-20. doi: 10.1111/vop.12134. [PMID: 24373492]
  • Arun Jose, Ratnasamy Selvakumar, John Victor Peter, Gunasekaran Karthik, Denise Helen Fleming, Jude Joseph Fleming. Estimation of Monocrotophos renal elimination half-life in humans. Clinical toxicology (Philadelphia, Pa.). 2015; 53(7):629-32. doi: 10.3109/15563650.2015.1054500. [PMID: 26065438]
  • Raju Nagaraju, Apurva Kumar Ramesh Joshi, Padmanabhan Sharda Rajini. Organophosphorus insecticide, monocrotophos, possesses the propensity to induce insulin resistance in rats on chronic exposure. Journal of diabetes. 2015 Jan; 7(1):47-59. doi: 10.1111/1753-0407.12158. [PMID: 24698518]
  • Jun Wang, Xin Bing, Kun Yu, Hua Tian, Wei Wang, Shaoguo Ru. Preparation of a polyclonal antibody against goldfish (Carassius auratus) vitellogenin and its application to detect the estrogenic effects of monocrotophos pesticide. Ecotoxicology and environmental safety. 2015 Jan; 111(?):109-16. doi: 10.1016/j.ecoenv.2014.10.007. [PMID: 25450922]
  • Xiaona Zhang, Hua Tian, Wei Wang, Shaoguo Ru. Monocrotophos pesticide decreases the plasma levels of total 3,3',5-triiodo-l-thyronine and alters the expression of genes associated with the thyroidal axis in female goldfish (Carassius auratus). PloS one. 2014; 9(9):e108972. doi: 10.1371/journal.pone.0108972. [PMID: 25268935]
  • Xiaona Zhang, Hua Tian, Wei Wang, Shaoguo Ru. Exposure to monocrotophos pesticide causes disruption of the hypothalamic-pituitary-thyroid axis in adult male goldfish (Carassius auratus). General and comparative endocrinology. 2013 Nov; 193(?):158-66. doi: 10.1016/j.ygcen.2013.08.003. [PMID: 23948368]
  • Qin Zhao, Qian Lu, Qiong-Wei Yu, Yu-Qi Feng. Dispersive microextraction based on "magnetic water" coupled to gas chromatography/mass spectrometry for the fast determination of organophosphorus pesticides in cold-pressed vegetable oils. Journal of agricultural and food chemistry. 2013 Jun; 61(22):5397-403. doi: 10.1021/jf400870m. [PMID: 23687955]
  • G Velmurugan, D D Venkatesh Babu, Subbiah Ramasamy. Prolonged monocrotophos intake induces cardiac oxidative stress and myocardial damage in rats. Toxicology. 2013 May; 307(?):103-8. doi: 10.1016/j.tox.2012.11.022. [PMID: 23228476]
  • R Rajasankar, G Manju Gayathry, A Sathiavelu, C Ramalingam, V S Saravanan. Pesticide tolerant and phosphorus solubilizing Pseudomonas sp. strain SGRAJ09 isolated from pesticides treated Achillea clavennae rhizosphere soil. Ecotoxicology (London, England). 2013 May; 22(4):707-17. doi: 10.1007/s10646-013-1062-0. [PMID: 23512438]
  • Vivek Kumar, Vinay K Tripathi, Abhishek K Singh, Mohathshim Lohani, Mohammed Kuddus. Trans-resveratrol restores the damages induced by organophosphate pesticide-monocrotophos in neuronal cells. Toxicology international. 2013 Jan; 20(1):48-55. doi: 10.4103/0971-6580.111571. [PMID: 23833438]
  • A Masoud, R Sandhir. Increased oxidative stress is associated with the development of organophosphate-induced delayed neuropathy. Human & experimental toxicology. 2012 Dec; 31(12):1214-27. doi: 10.1177/0960327112446842. [PMID: 22751200]
  • Ashwin B Patel, Aruna Dewan, Bharat C Kaji. Monocrotophos poisoning through contaminated millet flour. Arhiv za higijenu rada i toksikologiju. 2012 Sep; 63(3):377-83. doi: 10.2478/10004-1254-63-2012-2158. [PMID: 23152387]
  • Lei Xu, Hua Tian, Wei Wang, Shaoguo Ru. Effects of monocrotophos pesticide on serotonin metabolism during early development in the sea urchin, Hemicentrotus pulcherrimus. Environmental toxicology and pharmacology. 2012 Sep; 34(2):537-547. doi: 10.1016/j.etap.2012.06.014. [PMID: 22824501]
  • Madhusudan Reddy Narra, Ghousia Begum, Kodimyala Rajender, J Venkateswara Rao. Toxic impact of two organophosphate insecticides on biochemical parameters of a food fish and assessment of recovery response. Toxicology and industrial health. 2012 May; 28(4):343-52. doi: 10.1177/0748233711412423. [PMID: 21983276]
  • John E Casida. The greening of pesticide-environment interactions: some personal observations. Environmental health perspectives. 2012 Apr; 120(4):487-93. doi: 10.1289/ehp.1104405. [PMID: 22472325]
  • Kevin Chien-Chang Wu, Ying-Yeh Chen, Paul S F Yip. Suicide methods in Asia: implications in suicide prevention. International journal of environmental research and public health. 2012 04; 9(4):1135-58. doi: 10.3390/ijerph9041135. [PMID: 22690187]
  • Apurva Kumar Ramesh Joshi, Raju Nagaraju, Padmanabhan Sharda Rajini. Insights into the mechanisms mediating hyperglycemic and stressogenic outcomes in rats treated with monocrotophos, an organophosphorus insecticide. Toxicology. 2012 Mar; 294(1):9-16. doi: 10.1016/j.tox.2012.01.009. [PMID: 22305719]
  • Amajad Iqbal Kazi, Anna Oommen. Monocrotophos induced oxidative damage associates with severe acetylcholinesterase inhibition in rat brain. Neurotoxicology. 2012 Mar; 33(2):156-61. doi: 10.1016/j.neuro.2012.01.008. [PMID: 22285544]
  • Apurva Kumar R Joshi, P S Rajini. Hyperglycemic and stressogenic effects of monocrotophos in rats: evidence for the involvement of acetylcholinesterase inhibition. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 2012 Jan; 64(1-2):115-20. doi: 10.1016/j.etp.2010.07.003. [PMID: 20674316]
  • Poonam Sharma, Rambir Singh. Dichlorvos and lindane induced oxidative stress in rat brain: Protective effects of ginger. Pharmacognosy research. 2012 Jan; 4(1):27-32. doi: 10.4103/0974-8490.91031. [PMID: 22224058]
  • Satya Srinivas P, Kaushik Banerjee, Manjusha R Jadhav, Manoj S Ghaste, K E Lawande. Bioefficacy, dissipation kinetics and safety evaluation of selected insecticides in Allium cepa L. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2012; 47(7):700-9. doi: 10.1080/03601234.2012.669262. [PMID: 22560033]
  • Cátia S A Santos, Marta S Monteiro, Amadeu M V M Soares, Susana Loureiro. Characterization of cholinesterases in plasma of three Portuguese native bird species: application to biomonitoring. PloS one. 2012; 7(3):e33975. doi: 10.1371/journal.pone.0033975. [PMID: 22470503]
  • Khamrunissa Begum, P S Rajini. Augmentation of hepatic and renal oxidative stress and disrupted glucose homeostasis by monocrotophos in streptozotocin-induced diabetic rats. Chemico-biological interactions. 2011 Sep; 193(3):240-5. doi: 10.1016/j.cbi.2011.07.003. [PMID: 21821013]
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