Mepanipyrim (BioDeep_00001873834)

   


代谢物信息卡片


4-METHYL-N-PHENYL-6-(PROP-1-YNYL)PYRIMIDIN-2-AMINE

化学式: C14H13N3 (223.1109)
中文名称: 嘧菌胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC#CC1=NC(=NC(=C1)C)NC2=CC=CC=C2
InChI: InChI=1S/C14H13N3/c1-3-7-13-10-11(2)15-14(17-13)16-12-8-5-4-6-9-12/h4-6,8-10H,1-2H3,(H,15,16,17)

描述信息

同义名列表

3 个代谢物同义名

4-METHYL-N-PHENYL-6-(PROP-1-YNYL)PYRIMIDIN-2-AMINE; Mepanipyrim; Mepanipyrim



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 AHR, AR, ATF2, AXIN2, BDNF, CCND1, CTNNB1, DLG4, ESR1, GAD1, PGR, PIK3CA, SLC5A5
Golgi apparatus, trans-Golgi network membrane 1 DLG4
Peripheral membrane protein 2 CYP1B1, ESR1
Endosome membrane 2 BACE1, TF
Endoplasmic reticulum membrane 2 CYP1B1, NRF1
Nucleus 10 AHR, AR, ATF2, AXIN2, CCND1, CTNNB1, ESR1, NRF1, PGR, SLC5A5
cytosol 11 AHR, AR, AXIN2, CCND1, CTNNB1, DLG4, ESR1, NRF1, NRK, PGR, PIK3CA
dendrite 3 BACE1, BDNF, NLGN1
trans-Golgi network 2 BACE1, TGOLN2
centrosome 3 AXIN2, CCND1, CTNNB1
nucleoplasm 9 AHR, AR, ATF2, CCND1, CTNNB1, ESR1, NRF1, PGR, TGOLN2
RNA polymerase II transcription regulator complex 1 ATF2
Cell membrane 6 BACE1, CTNNB1, DLG4, ESR1, NLGN1, SLC5A5
Lipid-anchor 1 DLG4
Cytoplasmic side 2 DLG4, ESR1
lamellipodium 2 CTNNB1, PIK3CA
Cell projection, axon 2 BACE1, DLG4
Early endosome membrane 1 DLG4
Multi-pass membrane protein 1 SLC5A5
Golgi apparatus membrane 1 DLG4
Synapse 3 CTNNB1, DLG4, NLGN1
cell cortex 2 CTNNB1, GAD1
cell junction 2 CTNNB1, DLG4
cell surface 3 BACE1, NLGN1, TF
glutamatergic synapse 3 CTNNB1, DLG4, NLGN1
Golgi apparatus 4 BACE1, ESR1, NLGN1, TGOLN2
Golgi membrane 1 DLG4
neuromuscular junction 2 DLG4, NLGN1
neuronal cell body 1 BACE1
postsynapse 1 NLGN1
presynaptic membrane 1 CTNNB1
synaptic vesicle 3 BACE1, BDNF, DLG4
Lysosome 1 BACE1
Presynapse 2 DLG4, NLGN1
endosome 2 BACE1, TGOLN2
plasma membrane 13 AR, AXIN2, BACE1, CTNNB1, DLG4, ESR1, GAD1, NLGN1, PGR, PIK3CA, SLC5A5, TF, TGOLN2
presynaptic active zone 1 GAD1
Membrane 10 AR, BACE1, BDNF, CTNNB1, CYP1B1, ESR1, NLGN1, NRK, SLC5A5, TGOLN2
apical plasma membrane 1 TF
axon 3 BACE1, BDNF, DLG4
basolateral plasma membrane 2 CTNNB1, DLG4
extracellular exosome 4 CTNNB1, NRF1, SLC5A5, TF
endoplasmic reticulum 2 BACE1, DLG4
extracellular space 2 BDNF, TF
perinuclear region of cytoplasm 5 BDNF, CTNNB1, GAD1, PIK3CA, TF
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 2 CTNNB1, DLG4
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 2 CCND1, CTNNB1
intercalated disc 1 PIK3CA
mitochondrion 1 CYP1B1
protein-containing complex 4 AHR, AR, CTNNB1, ESR1
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 1 CYP1B1
postsynaptic density 2 DLG4, NLGN1
Single-pass type I membrane protein 2 BACE1, NLGN1
Secreted 2 BDNF, TF
extracellular region 2 BDNF, TF
mitochondrial outer membrane 2 ATF2, PGR
basal part of cell 1 TF
excitatory synapse 2 DLG4, NLGN1
hippocampal mossy fiber to CA3 synapse 1 BACE1
transcription regulator complex 3 AHR, CTNNB1, ESR1
Nucleus membrane 1 CCND1
nuclear membrane 1 CCND1
external side of plasma membrane 1 NLGN1
Extracellular vesicle 1 SLC5A5
multivesicular body 1 BACE1
dendritic spine 2 DLG4, NLGN1
Z disc 1 CTNNB1
beta-catenin destruction complex 2 AXIN2, CTNNB1
cytoplasmic vesicle 1 TF
Wnt signalosome 1 CTNNB1
neuron spine 1 DLG4
Early endosome 2 BACE1, TF
apical part of cell 1 CTNNB1
cell-cell junction 1 CTNNB1
clathrin-coated pit 1 TF
recycling endosome 2 BACE1, TF
Single-pass type II membrane protein 1 NRF1
vesicle 1 TF
postsynaptic membrane 3 CTNNB1, DLG4, NLGN1
filopodium tip 1 NLGN1
Membrane raft 1 BACE1
Cytoplasm, cytoskeleton 2 CTNNB1, DLG4
focal adhesion 1 CTNNB1
GABA-ergic synapse 2 GAD1, NLGN1
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
Cell projection, dendritic spine 1 DLG4
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
nuclear speck 1 AR
dendrite cytoplasm 1 DLG4
Late endosome 2 BACE1, TF
neuron to neuron synapse 1 NLGN1
receptor complex 1 NLGN1
neuron projection 1 DLG4
chromatin 6 AHR, AR, ATF2, ESR1, NRF1, PGR
cell periphery 1 CTNNB1
cytoskeleton 1 DLG4
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
Golgi apparatus, trans-Golgi network 1 BACE1
spindle pole 1 CTNNB1
blood microparticle 1 TF
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
site of double-strand break 1 ATF2
Endomembrane system 2 BACE1, CTNNB1
aryl hydrocarbon receptor complex 1 AHR
Cytoplasmic vesicle membrane 1 BACE1
AMPA glutamate receptor complex 1 DLG4
Cell projection, dendrite 2 BACE1, DLG4
euchromatin 2 CTNNB1, ESR1
basal plasma membrane 1 TF
Synaptic cell membrane 1 NLGN1
synaptic membrane 1 DLG4
trans-Golgi network membrane 1 DLG4
trans-Golgi network transport vesicle 1 TGOLN2
secretory granule lumen 1 TF
HFE-transferrin receptor complex 1 TF
endoplasmic reticulum lumen 4 BACE1, BDNF, TF, TGOLN2
transcription repressor complex 1 CCND1
cortical actin cytoskeleton 1 DLG4
axon terminus 1 GAD1
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
endocytic vesicle membrane 1 DLG4
endocytic vesicle 1 TF
transport vesicle 1 TGOLN2
cerebellar mossy fiber 1 DLG4
beta-catenin-TCF complex 1 CTNNB1
Single-pass type III membrane protein 1 NRF1
postsynaptic density membrane 1 DLG4
presynaptic active zone cytoplasmic component 1 CTNNB1
vesicle membrane 1 GAD1
clathrin-coated endocytic vesicle membrane 2 TF, TGOLN2
[Isoform 1]: Nucleus 1 ESR1
synaptic cleft 1 NLGN1
protein-DNA complex 1 CTNNB1
postsynaptic specialization membrane 1 NLGN1
catenin complex 1 CTNNB1
inhibitory synapse 1 GAD1
cyclin-dependent protein kinase holoenzyme complex 1 CCND1
vesicle coat 1 TF
cortical cytoskeleton 1 DLG4
[Isoform 4]: Mitochondrion outer membrane 1 PGR
neuron projection terminus 1 DLG4
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane 1 GAD1
cyclin D1-CDK4 complex 1 CCND1
H4 histone acetyltransferase complex 1 ATF2
beta-catenin-TCF7L2 complex 1 CTNNB1
juxtaparanode region of axon 1 DLG4
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
cyclin D1-CDK6 complex 1 CCND1
nuclear aryl hydrocarbon receptor complex 1 AHR
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
cytosolic aryl hydrocarbon receptor complex 1 AHR
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
Golgi-associated vesicle lumen 1 BACE1
protein complex involved in cell-cell adhesion 1 NLGN1
dense body 1 TF
Golgi cis cisterna 1 DLG4
[Endoplasmic reticulum membrane sensor NFE2L1]: Endoplasmic reticulum membrane 1 NRF1
[Transcription factor NRF1]: Nucleus 1 NRF1
asymmetric, glutamatergic, excitatory synapse 1 NLGN1


文献列表

  • Xuyang Liang, Xingang Liu, Fengshou Dong, Jun Xu, Dongmei Qin, Yuanbo Li, Yingying Tian, Ying Zhang, Yongtao Han, Yongquan Zheng. Simultaneous determination of pyrimethanil, cyprodinil, mepanipyrim and its metabolite in fresh and home-processed fruit and vegetables by a QuEChERS method coupled with UPLC-MS/MS. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2013; 30(4):713-21. doi: 10.1080/19440049.2013.768777. [PMID: 23410121]
  • Yong-Zhe Zhu, Young Soo Keum, Lin Yang, Hyeri Lee, Heewon Park, Jeong-Han Kim. Metabolism of a fungicide mepanipyrim by soil fungus Cunninghamella elegans ATCC36112. Journal of agricultural and food chemistry. 2010 Dec; 58(23):12379-84. doi: 10.1021/jf102980y. [PMID: 21047134]
  • Mark P McQuilken, J Thomson. Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris. Pest management science. 2008 Jul; 64(7):748-54. doi: 10.1002/ps.1552. [PMID: 18286666]
  • M Terada, F Mizuhashi, T Tomita, H Inoue, K Murata. Mepanipyrim induces fatty liver in rats but not in mice and dogs. The Journal of toxicological sciences. 1998 Aug; 23(3):223-34. doi: 10.2131/jts.23.3_223. [PMID: 9779415]
  • M Terada, F Mizuhashi, T Tomita, K Murata. Effects of mepanipyrim on lipid metabolism in rats. The Journal of toxicological sciences. 1998 Aug; 23(3):235-41. doi: 10.2131/jts.23.3_235. [PMID: 9779416]