Desthiobiotin (BioDeep_00001868851)

Main id: BioDeep_00000001323

 

PANOMIX_OTCML-2023 BioNovoGene_Lab2019 natural product


代谢物信息卡片


dl-Dithiobiotin

化学式: C10H18N2O3 (214.1317)
中文名称: 5-甲基-2-氧-4-咪唑啉己酸, d-Desthiobiotin
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(NC(=O)N1)CCCCCC(=O)O
InChI: InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)

描述信息

D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
D050258 - Mitosis Modulators > D008934 - Mitogens
D-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography. D-Desthiobiotin also can be used for protein and cell labeling, detection and isolation[1].

同义名列表

5 个代谢物同义名

dl-Dithiobiotin; Desthiobiotin; Dethiobiotin; D-Desthiobiotin; Dethiobiotin



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

13 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AK4, BIRC5, FABP5, HMGCS1, MAP2K2, MAP2K3, PFAS, PTK2B, TLR4, VEGFA
Peripheral membrane protein 1 MAP2K2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 2 HSP90B1, MLANA
Nucleus 7 BIRC5, FABP5, HSP90B1, MAP2K2, PARP1, PTK2B, VEGFA
cytosol 10 BIRC5, FABP5, HMGCS1, HSP90B1, LIPA, MAP2K2, MAP2K3, PARP1, PFAS, PTK2B
dendrite 1 PTK2B
nuclear body 1 PARP1
trans-Golgi network 1 MLANA
nucleoplasm 5 BIRC5, FABP5, LIPA, MAP2K3, PARP1
Cell membrane 4 AGTR1, CD8A, SLC5A6, TLR4
lamellipodium 1 PTK2B
Multi-pass membrane protein 2 AGTR1, SLC5A6
Synapse 1 FABP5
cell cortex 1 PTK2B
cell surface 2 TLR4, VEGFA
glutamatergic synapse 2 FABP5, PTK2B
Golgi apparatus 3 MAP2K2, MLANA, VEGFA
growth cone 1 PTK2B
neuronal cell body 1 PTK2B
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 PARP1
Lysosome 1 LIPA
Presynapse 1 PTK2B
plasma membrane 7 AGTR1, CD8A, FABP5, MLANA, PTK2B, SLC5A6, TLR4
Membrane 8 AGTR1, HSP90B1, MAP2K2, MAP2K3, PARP1, SLC5A6, TLR4, VEGFA
apical plasma membrane 1 SLC5A6
basolateral plasma membrane 1 SLC5A6
extracellular exosome 4 BTD, FABP5, HSP90B1, PFAS
endoplasmic reticulum 3 HSP90B1, MAP2K2, VEGFA
extracellular space 5 BTD, FABP5, IL2, THPO, VEGFA
lysosomal lumen 1 LIPA
perinuclear region of cytoplasm 4 HSP90B1, MAP2K2, PTK2B, TLR4
Schaffer collateral - CA1 synapse 1 PTK2B
adherens junction 1 VEGFA
mitochondrion 3 AK4, MAP2K2, PARP1
protein-containing complex 3 BIRC5, HSP90B1, PARP1
intracellular membrane-bounded organelle 1 LIPA
postsynaptic density 2 FABP5, PTK2B
Single-pass type I membrane protein 2 CD8A, TLR4
Secreted 4 FABP5, IL2, THPO, VEGFA
extracellular region 8 BTD, CD8A, FABP5, HSP90B1, IL2, MAP2K2, THPO, VEGFA
cytoplasmic side of plasma membrane 1 MAP2K2
[Isoform 2]: Secreted 1 CD8A
Mitochondrion matrix 1 AK4
mitochondrial matrix 2 AK4, BTD
transcription regulator complex 1 PARP1
external side of plasma membrane 2 CD8A, TLR4
Secreted, extracellular space, extracellular matrix 1 VEGFA
dendritic spine 1 PTK2B
microtubule cytoskeleton 1 BIRC5
nucleolus 1 PARP1
Melanosome membrane 1 MLANA
midbody 2 BIRC5, HSP90B1
Early endosome 2 MAP2K2, TLR4
cell-cell junction 1 MAP2K2
Apical cell membrane 1 SLC5A6
Cytoplasm, cytoskeleton, spindle 1 BIRC5
focal adhesion 3 HSP90B1, MAP2K2, PTK2B
microtubule 2 BIRC5, MAP2K2
spindle 1 BIRC5
extracellular matrix 1 VEGFA
peroxisomal membrane 1 MAP2K2
collagen-containing extracellular matrix 1 HSP90B1
secretory granule 1 VEGFA
interphase microtubule organizing center 1 BIRC5
Cell projection, ruffle 1 TLR4
Late endosome 1 MAP2K2
ruffle 1 TLR4
receptor complex 2 CD8A, TLR4
chromatin 1 PARP1
phagocytic cup 1 TLR4
Chromosome 2 BIRC5, PARP1
cytoskeleton 1 PTK2B
centriole 1 BIRC5
Secreted, extracellular space 1 BTD
brush border membrane 1 SLC5A6
Nucleus, nucleolus 1 PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
nuclear chromosome 1 BIRC5
postsynaptic density, intracellular component 2 FABP5, PTK2B
site of double-strand break 1 PARP1
fibrillar center 1 LIPA
nuclear envelope 1 PARP1
Chromosome, centromere 1 BIRC5
Chromosome, centromere, kinetochore 1 BIRC5
Melanosome 2 HSP90B1, MLANA
cell body 1 PTK2B
sperm plasma membrane 1 HSP90B1
basal plasma membrane 1 SLC5A6
lipopolysaccharide receptor complex 1 TLR4
plasma membrane raft 1 CD8A
secretory granule membrane 1 FABP5
endoplasmic reticulum lumen 1 HSP90B1
platelet alpha granule lumen 1 VEGFA
kinetochore 1 BIRC5
azurophil granule lumen 1 FABP5
chromosome, centromeric region 1 BIRC5
Sarcoplasmic reticulum lumen 1 HSP90B1
chromosome passenger complex 1 BIRC5
cytoplasmic microtubule 1 BIRC5
protein-DNA complex 1 PARP1
spindle microtubule 1 BIRC5
survivin complex 1 BIRC5
NMDA selective glutamate receptor complex 1 PTK2B
apical dendrite 1 PTK2B
[Isoform 1]: Cell membrane 1 CD8A
postsynaptic cytosol 1 FABP5
site of DNA damage 1 PARP1
endocytic vesicle lumen 1 HSP90B1
T cell receptor complex 1 CD8A
endoplasmic reticulum chaperone complex 1 HSP90B1
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA


文献列表

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