Dehydrodiisoeugenol (BioDeep_00000178025)
human metabolite blood metabolite natural product
代谢物信息卡片
2-methoxy-4-[7-methoxy-3-methyl-5-(prop-1-en-1-yl)-2,3-dihydro-1-benzofuran-2-yl]phenol
化学式: C20H22O4 (326.1518)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 53.95%
分子结构信息
SMILES: CC=Cc1cc(OC)c2c(c1)C(C)C(c1ccc(O)c(OC)c1)O2
InChI: InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
59 个相关的物种来源信息
- 4206 - Adoxaceae: LTS0185228
- 22140 - Annonaceae: LTS0185228
- 158557 - Aristolochia maxima: 10.1016/S0031-9422(99)00176-4
- 171877 - Aristolochia taliscana: 10.1016/S0031-9422(99)00176-4
- 235719 - Cremastosperma: LTS0185228
- 235720 - Cremastosperma microcarpum: 10.1055/S-0030-1270960
- 235720 - Cremastosperma microcarpum: LTS0185228
- 2759 - Eukaryota: LTS0185228
- 9606 - Homo sapiens: -
- 224860 - Iryanthera: LTS0185228
- 477925 - Iryanthera lancifolia: 10.1016/J.BMC.2007.12.003
- 477925 - Iryanthera lancifolia: LTS0185228
- 66688 - Krameria: LTS0185228
- 2042419 - Krameria bicolor: 10.1016/0031-9422(94)00932-J
- 2042419 - Krameria bicolor: LTS0185228
- 228638 - Krameria grayi: 10.1016/0031-9422(94)00932-J
- 228638 - Krameria grayi: LTS0185228
- 66687 - Krameriaceae: LTS0185228
- 4136 - Lamiaceae: LTS0185228
- 3433 - Lauraceae: LTS0185228
- 378905 - Leucas: LTS0185228
- 483811 - Leucas aspera: 10.1248/CPB.51.595
- 483811 - Leucas aspera: LTS0185228
- 251260 - Machilus: LTS0185228
- 325535 - Machilus japonica: 10.1016/S0031-9422(00)90571-5
- 325535 - Machilus japonica: LTS0185228
- 128685 - Machilus thunbergii:
- 128685 - Machilus thunbergii: 10.1016/0031-9422(91)84145-I
- 128685 - Machilus thunbergii: 10.1016/S0031-9422(00)81847-6
- 128685 - Machilus thunbergii: LTS0185228
- 3402 - Magnolia: LTS0185228
- 111567 - Magnolia kachirachirai: 10.1016/S0031-9422(00)84117-5
- 111567 - Magnolia kachirachirai: LTS0185228
- 152188 - Magnolia ovata: 10.1021/NP900203Y
- 3401 - Magnoliaceae: LTS0185228
- 3398 - Magnoliopsida: LTS0185228
- 51088 - Myristica: LTS0185228
- 2086458 - Myristica castaneifolia: 10.1071/CH9931421
- 2086458 - Myristica castaneifolia: LTS0185228
- 51089 - Myristica fragrans: 10.1002/HLCA.200790155
- 51089 - Myristica fragrans: 10.1007/BF01945432
- 51089 - Myristica fragrans: LTS0185228
- 22274 - Myristicaceae: LTS0185228
- 63800 - Nectandra: LTS0185228
- 128645 - Nectandra amazonum: 10.1248/CPB.57.1437
- 128645 - Nectandra amazonum: LTS0185228
- 63801 - Ocotea: LTS0185228
- 1365881 - Ocotea porosa: 10.1016/S0031-9422(00)97102-4
- 1365881 - Ocotea porosa: LTS0185228
- 16748 - Saururaceae: LTS0185228
- 13259 - Saururus: LTS0185228
- 13260 - Saururus cernuus: 10.1016/S0031-9422(00)00076-5
- 13260 - Saururus cernuus: LTS0185228
- 35493 - Streptophyta: LTS0185228
- 58023 - Tracheophyta: LTS0185228
- 4204 - Viburnum: LTS0185228
- 237931 - Viburnum cylindricum: 10.1002/HLCA.200800420
- 237931 - Viburnum cylindricum: LTS0185228
- 33090 - Viridiplantae: LTS0185228
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Atsuyoshi Nishina, Motohiko Ukiya, Kazuki Motegi, Risa Kiryu, Daisuke Sato, Mitsuru Sada, Yuki Hori, Hideo Satsu, Kazuhiro Uemura, Mamoru Koketsu, Masayuki Ninomiya, Lwin Mon Mon Myint, Hirokazu Kimura. Promotion of ABCG2 gene expression by neolignans from Piper longum L.
Bioscience, biotechnology, and biochemistry.
2023 Sep; ?(?):. doi:
10.1093/bbb/zbad132. [PMID: 37709570] - Armelle T Mbaveng, Brice E N Wamba, Gabin T M Bitchagno, Simplice Beaudelaire Tankeo, İlhami Çelik, Brice C K Atontsa, Antoine H Nkuété Lonfouo, Victor Kuete, Thomas Efferth. Bioactivity of fractions and constituents of Piper capense fruits towards a broad panel of cancer cells.
Journal of ethnopharmacology.
2021 May; 271(?):113884. doi:
10.1016/j.jep.2021.113884. [PMID: 33529639] - Dalila Junqueira Alvarenga, Laira Maria Faria Matias, Lucas Martins Oliveira, Luiz Paulo Melchior de Oliveira Leão, Jamie Anthony Hawkes, Breno Vilas Boas Raimundo, Lívia de Figueiredo Diniz Castro, Marli Matiko Anraku de Campos, Fallon Dos Santos Siqueira, Thiago Dos Santos, Diogo Teixeira Carvalho. Exploring how structural changes to new Licarin A derivatives effects their bioactive properties against rapid growing mycobacteria and biofilm formation.
Microbial pathogenesis.
2020 Jul; 144(?):104203. doi:
10.1016/j.micpath.2020.104203. [PMID: 32304794] - Thiago R Morais, Geanne A Alves Conserva, Marina T Varela, Thais A Costa-Silva, Fernanda Thevenard, Vitor Ponci, Ana Fortuna, Amílcar C Falcão, Andre G Tempone, João Paulo S Fernandes, João Henrique G Lago. Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A.
Scientific reports.
2020 03; 10(1):5467. doi:
10.1038/s41598-020-62352-w. [PMID: 32214193] - Uma Maheswari, Krishna Ghosh, Sudha Rani Sadras. Licarin A induces cell death by activation of autophagy and apoptosis in non-small cell lung cancer cells.
Apoptosis : an international journal on programmed cell death.
2018 04; 23(3-4):210-225. doi:
10.1007/s10495-018-1449-8. [PMID: 29468481] - Dahyeon Yoon, Khan Mohammad Imran, Yong-Sik Kim. Distinctive effects of licarin A on lipolysis mediated by PKA and on formation of brown adipocytes from C3H10T1/2 mesenchymal stem cells.
Toxicology and applied pharmacology.
2018 02; 340(?):9-20. doi:
10.1016/j.taap.2017.12.015. [PMID: 29288687] - Takuya Matsui, Chihiro Ito, Satoru Masubuchi, Masataka Itoigawa. Licarin A is a candidate compound for the treatment of immediate hypersensitivity via inhibition of rat mast cell line RBL-2H3 cells.
The Journal of pharmacy and pharmacology.
2015 Dec; 67(12):1723-32. doi:
10.1111/jphp.12475. [PMID: 26376734] - M M O Cabral, J M Barbosa-Filho, G L A Maia, M C O Chaves, M V Braga, W De Souza, R O A Soares. Neolignans from plants in northeastern Brazil (Lauraceae) with activity against Trypanosoma cruzi.
Experimental parasitology.
2010 Mar; 124(3):319-24. doi:
10.1016/j.exppara.2009.11.007. [PMID: 19944690] - Letícia Ferrari L Barros, Andersson Barison, Marcos José Salvador, Renato de Mello-Silva, Elaine C Cabral, Marcos N Eberlin, Maria Elida A Stefanello. Constituents of the leaves of Magnolia ovata.
Journal of natural products.
2009 Aug; 72(8):1529-32. doi:
10.1021/np900203y. [PMID: 19658431] - Fei Li, Xiu-Wei Yang. Simultaneous determination of diastereomers (+)-licarin A and isolicarin A from Myristica fragrans in rat plasma by HPLC and its application to their pharmacokinetics.
Planta medica.
2008 Jun; 74(8):880-4. doi:
10.1055/s-2008-1074545. [PMID: 18523922] - E S Garcia, P Azambuja. Lignoids in insects: chemical probes for the study of ecdysis, excretion and Trypanosoma cruzi-triatomine interactions.
Toxicon : official journal of the International Society on Toxinology.
2004 Sep; 44(4):431-40. doi:
10.1016/j.toxicon.2004.05.007. [PMID: 15302525]
