Adenosine diphosphate (BioDeep_00000001284)

 

Secondary id: BioDeep_00000400395, BioDeep_00001890787

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid

化学式: C10H15N5O10P2 (427.0294)
中文名称: 二磷酸腺苷, 腺苷-5'-二磷酸 钠盐, 腺苷二磷酸, 腺苷-5'-二磷酸
谱图信息: 最多检出来源 Homo sapiens(blood) 10.54%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

Adenosine diphosphate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/adenosine_diphosphate (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000001284). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c(N)ncnc23)O1)O)O)OP(=O)(O)OP(=O)(O)O
InChI: InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

描述信息

Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells. ADP consists of three important structural components: a sugar backbone attached to adenine and two phosphate groups bonded to the 5 carbon atom of ribose. The diphosphate group of ADP is attached to the 5’ carbon of the sugar backbone, while the adenine attaches to the 1’ carbon. ADP belongs to the class of organic compounds known as purine ribonucleoside diphosphates. These are purine ribobucleotides with diphosphate group linked to the ribose moiety. It is an ester of pyrophosphoric acid with the nucleotide adenine. Adenosine diphosphate is a nucleotide. ADP exists in all living species, ranging from bacteria to humans. In humans, ADP is involved in d4-gdi signaling pathway. ADP is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ADP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine.
Adenosine diphosphate, abbreviated ADP, is a nucleotide. It is an ester of pyrophosphoric acid with the nucleotide adenine. ADP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine.

5′-ADP. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=58-64-0 (retrieved 2024-07-01) (CAS RN: 58-64-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.

同义名列表

28 个代谢物同义名

[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid; Adenosine-5-diphosphate Di(monocyclohexylammonium)salt; Adenosine 5-diphosphoric acid; ADENOSINE-5-diphosphoric acid; Adenosine diphosphoric acid; 5-Pyrophosphate, adenosine; Adenosine 5-pyrophosphate; Adenosine diphosphate;ADP; Adenosine 5 pyrophosphate; Adenosindiphosphorsaeure; Pyrophosphate, adenosine; Adenosine pyrophosphate; 5-Adenylphosphoric acid; ADENOSINE-5-diphosphATE; Adenosine-5-diphosphate; Adenosine 5-diphosphate; Diphosphate, adenosine; Adenosine diphosphate; Adenosine-diphosphate; 5-Adenylphosphate; ADP, Magnesium; Magnesium ADP; MgADP; H3ADP; ADP; Adenosine-5'-diphosphate(ADP); Adenosine 5'-diphosphate; ADP



数据库引用编号

37 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(7)

BioCyc(83)

PlantCyc(0)

代谢反应

14593 个相关的代谢反应过程信息。

Reactome(1363)

BioCyc(655)

WikiPathways(4)

Plant Reactome(4764)

INOH(46)

PlantCyc(6)

COVID-19 Disease Map(3)

PathBank(7752)

PharmGKB(0)

59 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ADA, CASP3, CAT, CMPK2, G6PD, GAPDH, PF4, PRKX, RAD51, RHOA, XDH
Peripheral membrane protein 2 ADA, G6PD
Endoplasmic reticulum membrane 2 HSP90B1, RHOA
Nucleus 8 CASP3, GAPDH, HSP90B1, ITGB3, PARP2, PRKX, RAD51, RHOA
cytosol 9 ADA, CASP3, CAT, G6PD, GAPDH, HSP90B1, RAD51, RHOA, XDH
centrosome 1 RAD51
nucleoplasm 6 CASP3, CMPK2, ITGB3, PARP2, PRKX, RAD51
Cell membrane 4 ADA, ITGB3, P2RX1, RHOA
Lipid-anchor 1 RHOA
Cytoplasmic side 1 RHOA
Cleavage furrow 1 RHOA
lamellipodium 1 RHOA
ruffle membrane 2 ITGB3, RHOA
Multi-pass membrane protein 2 ENTPD1, P2RX1
Synapse 1 ITGB3
cell cortex 1 RHOA
cell junction 2 ADA, RHOA
cell surface 4 ADA, CD38, F3, ITGB3
glutamatergic synapse 4 CASP3, ITGB3, P2RX1, RHOA
Golgi membrane 1 INS
neuronal cell body 1 CASP3
postsynapse 2 P2RX1, RHOA
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 2 G6PD, GAPDH
Lysosome 1 ADA
endosome 1 RHOA
plasma membrane 8 ADA, CD38, ENTPD1, F3, GAPDH, ITGB3, P2RX1, RHOA
Membrane 11 ADA, CAT, CD38, ENTPD1, F3, G6PD, GAPDH, HSP90B1, HSPE1, ITGB3, P2RX1
apical plasma membrane 1 ITGB3
basolateral plasma membrane 1 CD38
caveola 1 ENTPD1
extracellular exosome 9 CAT, CD38, ENTPD1, G6PD, GAPDH, HSP90B1, HSPE1, ITGB3, RHOA
endoplasmic reticulum 1 HSP90B1
extracellular space 4 F3, INS, PF4, XDH
perinuclear region of cytoplasm 3 GAPDH, HSP90B1, RAD51
mitochondrion 4 CAT, CMPK2, HSPE1, RAD51
protein-containing complex 5 CAT, HSP90B1, ITGB3, P2RX1, RAD51
intracellular membrane-bounded organelle 3 CAT, G6PD, GAPDH
postsynaptic density 1 CASP3
Single-pass type I membrane protein 2 F3, ITGB3
Secreted 2 INS, PF4
extracellular region 4 CAT, HSP90B1, INS, PF4
cytoplasmic side of plasma membrane 2 G6PD, RHOA
[Isoform 1]: Membrane 1 F3
[Isoform 2]: Secreted 1 F3
Mitochondrion matrix 1 RAD51
mitochondrial matrix 3 CAT, HSPE1, RAD51
Extracellular side 1 ADA
Cytoplasmic vesicle lumen 1 ADA
anchoring junction 1 ADA
centriolar satellite 1 G6PD
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 RAD51
nuclear membrane 2 CD38, GAPDH
external side of plasma membrane 4 ADA, F3, ITGB3, P2RX1
dendritic spine 1 RHOA
microtubule cytoskeleton 1 GAPDH
nucleolus 2 PARP2, RAD51
midbody 2 HSP90B1, RHOA
cell-cell junction 1 ITGB3
Single-pass type II membrane protein 1 CD38
vesicle 2 GAPDH, RHOA
postsynaptic membrane 2 ITGB3, P2RX1
presynaptic active zone membrane 1 P2RX1
Cell projection, lamellipodium 1 RHOA
Cytoplasm, perinuclear region 1 GAPDH
Membrane raft 1 P2RX1
Cell junction, focal adhesion 1 ITGB3
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 4 CAT, HSP90B1, ITGB3, RHOA
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
PML body 1 RAD51
collagen-containing extracellular matrix 3 F3, HSP90B1, PF4
Postsynaptic cell membrane 1 ITGB3
receptor complex 1 ITGB3
chromatin 1 RAD51
cell periphery 1 RHOA
Chromosome 2 PARP2, RAD51
cytoskeleton 2 GAPDH, RHOA
chromosome, telomeric region 1 RAD51
nuclear chromosome 1 RAD51
Cytoplasm, cell cortex 1 RHOA
microvillus membrane 1 ITGB3
site of double-strand break 1 RAD51
endosome lumen 1 INS
Lipid droplet 1 GAPDH
Membrane, caveola 1 ENTPD1
lateral element 1 RAD51
Cell projection, dendrite 1 RHOA
specific granule membrane 1 P2RX1
Melanosome 2 HSP90B1, ITGB3
sperm plasma membrane 1 HSP90B1
filopodium membrane 1 ITGB3
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
secretory granule membrane 2 P2RX1, RHOA
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 HSP90B1, INS
male germ cell nucleus 1 RAD51
platelet alpha granule lumen 1 PF4
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
condensed nuclear chromosome 1 RAD51
Sarcoplasmic reticulum lumen 1 HSP90B1
ribonucleoprotein complex 1 GAPDH
ficolin-1-rich granule membrane 1 RHOA
death-inducing signaling complex 1 CASP3
apical junction complex 1 RHOA
condensed chromosome 1 RAD51
GAIT complex 1 GAPDH
platelet alpha granule membrane 1 ITGB3
site of DNA damage 1 PARP2
integrin complex 1 ITGB3
lamellipodium membrane 1 ITGB3
endocytic vesicle lumen 1 HSP90B1
alphav-beta3 integrin-vitronectin complex 1 ITGB3
catalase complex 1 CAT
alphav-beta3 integrin-IGF-1-IGF1R complex 1 ITGB3
Cell projection, lamellipodium membrane 1 ITGB3
alpha9-beta1 integrin-ADAM8 complex 1 ITGB3
alphav-beta3 integrin-HMGB1 complex 1 ITGB3
alphav-beta3 integrin-PKCalpha complex 1 ITGB3
glycinergic synapse 1 ITGB3
integrin alphaIIb-beta3 complex 1 ITGB3
integrin alphav-beta3 complex 1 ITGB3
presynaptic intermediate filament cytoskeleton 1 RAD51
endoplasmic reticulum chaperone complex 1 HSP90B1
serine-type peptidase complex 1 F3
nuclear ubiquitin ligase complex 1 RAD51


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