Classification Term: 167911
黃烷酮 (ontology term: 0a39d834db6e0eb8fbc2ffde91979014)
黃烷酮
found 479 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: 黄酮类
Child Taxonomies: There is no child term of current ontology term.
Liquiritin
Liquiritin is a flavanone glycoside that is liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It has a role as a plant metabolite, an anticoronaviral agent and an anti-inflammatory agent. It is a flavanone glycoside, a beta-D-glucoside, a monosaccharide derivative and a monohydroxyflavanone. It is functionally related to a liquiritigenin. Liquiritin is a natural product found in Polygonum aviculare, Artemisia capillaris, and other organisms with data available. See also: Glycyrrhiza Glabra (part of); Glycyrrhiza uralensis Root (part of). Liquiritin is found in herbs and spices. Liquiritin is isolated from Glycyrrhiza glabra (licorice) and Glycyrrhiza uralensis (Chinese licorice Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2]. Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2].
Isoliquiritigenin
Isoliquiritigenin is a member of the class of chalcones that is trans-chalcone hydroxylated at C-2, -4 and -4. It has a role as an EC 1.14.18.1 (tyrosinase) inhibitor, a biological pigment, a NMDA receptor antagonist, a GABA modulator, a metabolite, an antineoplastic agent and a geroprotector. It is functionally related to a trans-chalcone. It is a conjugate acid of an isoliquiritigenin(1-). Isoliquiritigenin is a precursor to several flavonones in many plants. Isoliquiritigenin is a natural product found in Pterocarpus indicus, Dracaena draco, and other organisms with data available. See also: Glycyrrhiza Glabra (part of); Glycyrrhiza uralensis Root (part of); Pterocarpus marsupium wood (part of). Isolated from Medicago subspecies Isoliquiritigenin is found in many foods, some of which are cocoa bean, purple mangosteen, blackcurrant, and chives. A member of the class of chalcones that is trans-chalcone hydroxylated at C-2, -4 and -4. Isoliquiritigenin is found in pulses. Isoliquiritigenin is isolated from Medicago specie D004791 - Enzyme Inhibitors Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM. Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM.
Pinocembrin
Pinocembrin is a dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea. It has a role as an antioxidant, an antineoplastic agent, a vasodilator agent, a neuroprotective agent and a metabolite. It is a dihydroxyflavanone and a (2S)-flavan-4-one. Pinocembrin is a natural product found in Prunus leveilleana, Alpinia rafflesiana, and other organisms with data available. Pinocembrin is found in mexican oregano and is isolated from many plants including food plants. Pinocembrin belongs to the family of flavanones. These are compounds containing a flavan-3-one moiety, which structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3. A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea. Isolated from many plants including food plants. (S)-Pinocembrin is found in mexican oregano and pine nut. (±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line[1]. (±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line[1]. Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties[1]. Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase, and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties[1].
Methyl
Methyl hesperidin is a flavanone glycoside that is hesperidin in which the hydroxy group at position 3 has been replaced by a methoxy group. It is a monohydroxyflavanone, a dimethoxyflavanone, a disaccharide derivative, a flavanone glycoside, a rutinoside, a member of 4-methoxyflavanones and a member of 3-methoxyflavanones. It is functionally related to a hesperidin. Methyl hesperidin is a natural product found in Plantago depressa, Citrus deliciosa, and Citrus reticulata with data available. Methyl-Hesperidin is a vasodilating agent[1]. Methyl-Hesperidin is a vasodilating agent[1].
Eriodictyol
Eriodictyol, also known as 3,4,5,7-tetrahydroxyflavanone or 2,3-dihydroluteolin, belongs to the class of organic compounds known as flavanones. Flavanones are compounds containing a flavan-3-one moiety, with a structure characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3. Thus, eriodictyol is considered to be a flavonoid lipid molecule. Outside of the human body, eriodictyol has been detected, but not quantified in, several different foods, such as common oregano, common thymes, parsley, sweet basils, and tarragons. This could make eriodictyol a potential biomarker for the consumption of these foods. Eriodictyol is a compound isolated from Eriodictyon californicum and can be used in medicine as an expectorant. BioTransformer predicts that eriodictiol is a product of luteolin metabolism via a flavonoid-c-ring-reduction reaction catalyzed by an unspecified-gut microbiota enzyme (PMID: 30612223). Eriodictyol, also known as 5735-tetrahydroxyflavanone, is a member of the class of compounds known as flavanones. Flavanones are compounds containing a flavan-3-one moiety, with a structure characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3. Eriodictyol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Eriodictyol can be found in a number of food items such as rowal, grape, cardamom, and lemon balm, which makes eriodictyol a potential biomarker for the consumption of these food products. Eriodictyol is a bitter-masking flavanone, a flavonoid extracted from yerba santa (Eriodictyon californicum), a plant native to North America. Eriodictyol is one of the four flavanones identified in this plant as having taste-modifying properties, the other three being homoeriodictyol, its sodium salt, and sterubin . Eriodictyol is a tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3 and 4 respectively. It is a tetrahydroxyflavanone and a member of 3-hydroxyflavanones. Eriodictyol is a natural product found in Eupatorium album, Eupatorium hyssopifolium, and other organisms with data available. A tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3 and 4 respectively. Acquisition and generation of the data is financially supported in part by CREST/JST. Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 18 nM. Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 18 nM.
Hesperidin
Hesperidin is an abundant and inexpensive by-product of Citrus cultivation and is the major flavonoid in sweet orange and lemon. In young immature oranges it can account for up to 14\\\\% of the fresh weight of the fruit. Hesperidin is an abundant and inexpensive by-product of Citrus cultivation and is the major flavonoid in sweet orange and lemon. In young immature oranges it can account for up to 14\\\\% of the fresh weight of the fruit due to vitamin C deficiency such as bruising due to capillary fragility were found in early studies to be relieved by crude vitamin C extract but not by purified vitamin C. The bioflavonoids, formerly called "vitamin P", were found to be the essential components in correcting this bruising tendency and improving the permeability and integrity of the capillary lining. These bioflavonoids include hesperidin, citrin, rutin, flavones, flavonols, catechin and quercetin. Of historical importance is the observation that "citrin", a mixture of two flavonoids, eriodictyol and hesperidin, was considered to possess a vitamin-like activity, as early as in 1949. Hesperidin deficiency has since been linked with abnormal capillary leakiness as well as pain in the extremities causing aches, weakness and night leg cramps. Supplemental hesperidin also helps in reducing oedema or excess swelling in the legs due to fluid accumulation. As with other bioflavonoids, hesperidin works best when administered concomitantly with vitamin C. No signs of toxicity have been observed with normal intake of hesperidin. Hesperidin was first discovered in 1827, by Lebreton, but not in a pure state and has been under continuous investigation since then (PMID:11746857). Hesperidin is a disaccharide derivative that consists of hesperetin substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a mutagen. It is a disaccharide derivative, a member of 3-hydroxyflavanones, a dihydroxyflavanone, a monomethoxyflavanone, a flavanone glycoside, a member of 4-methoxyflavanones and a rutinoside. It is functionally related to a hesperetin. Hesperidin is a flavan-on glycoside found in citrus fruits. Hesperidin is a natural product found in Ficus erecta var. beecheyana, Citrus tankan, and other organisms with data available. A flavanone glycoside found in CITRUS fruit peels. See also: Tangerine peel (part of). Found in most citrus fruits and other members of the Rutaceae, also in Mentha longifolia Acquisition and generation of the data is financially supported in part by CREST/JST. COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials relative retention time with respect to 9-anthracene Carboxylic Acid is 0.770 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.767 [Raw Data] CB217_Hesperidin_pos_50eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_20eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_30eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_10eV_CB000076.txt [Raw Data] CB217_Hesperidin_pos_40eV_CB000076.txt [Raw Data] CB217_Hesperidin_neg_20eV_000038.txt [Raw Data] CB217_Hesperidin_neg_50eV_000038.txt [Raw Data] CB217_Hesperidin_neg_10eV_000038.txt [Raw Data] CB217_Hesperidin_neg_30eV_000038.txt [Raw Data] CB217_Hesperidin_neg_40eV_000038.txt Annotation level-1 Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2]. Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2].
Hesperetin
Hesperetin, also known as prestwick_908 or YSO2, belongs to the class of organic compounds known as 4-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C4 atom of the flavonoid backbone. Thus, hesperetin is considered to be a flavonoid lipid molecule. Hesperetin also seems to upregulate the LDL receptor. Hesperetin, in the form of its glycoside , is the predominant flavonoid in lemons and oranges. Hesperetin is a drug which is used for lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase activity. Hesperetin is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. Hesperetin is a bitter tasting compound. Hesperetin is found, on average, in the highest concentration within a few different foods, such as limes, persian limes, and sweet oranges and in a lower concentration in pummelo, welsh onions, and lemons. Hesperetin has also been detected, but not quantified, in several different foods, such as yellow bell peppers, carrots, rapinis, hazelnuts, and beers. Hesperetin is a biomarker for the consumption of citrus fruits. Hesperetin reduces or inhibits the activity of acyl-coenzyme A:cholesterol acyltransferase genes (ACAT1 and ACAT2) and it reduces microsomal triglyceride transfer protein (MTP) activity. Hesperetin is a trihydroxyflavanone having the three hydroxy gropus located at the 3-, 5- and 7-positions and an additional methoxy substituent at the 4-position. It has a role as an antioxidant, an antineoplastic agent and a plant metabolite. It is a monomethoxyflavanone, a trihydroxyflavanone, a member of 3-hydroxyflavanones and a member of 4-methoxyflavanones. It is a conjugate acid of a hesperetin(1-). Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges. Hesperetin is a natural product found in Brassica oleracea var. sabauda, Dalbergia parviflora, and other organisms with data available. Isolated from Mentha (peppermint) and numerous Citrussubspecies, with lemons, tangerines and oranges being especially good sources. Nutriceutical with anti-cancer props. Glycosides also widely distributed A trihydroxyflavanone having the three hydroxy gropus located at the 3-, 5- and 7-positions and an additional methoxy substituent at the 4-position. Acquisition and generation of the data is financially supported in part by CREST/JST. [Raw Data] CB046_Hesperetin_pos_40eV_CB000021.txt [Raw Data] CB046_Hesperetin_pos_50eV_CB000021.txt [Raw Data] CB046_Hesperetin_pos_30eV_CB000021.txt [Raw Data] CB046_Hesperetin_pos_20eV_CB000021.txt [Raw Data] CB046_Hesperetin_pos_10eV_CB000021.txt [Raw Data] CB046_Hesperetin_neg_20eV_000014.txt [Raw Data] CB046_Hesperetin_neg_10eV_000014.txt [Raw Data] CB046_Hesperetin_neg_40eV_000014.txt [Raw Data] CB046_Hesperetin_neg_50eV_000014.txt [Raw Data] CB046_Hesperetin_neg_30eV_000014.txt Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin regulates apoptosis.
Liquiritigenin
Liquiritigenin is a dihydroxyflavanone compound having the two hydroxy substituents at the 4- and 7-positions. Isolated from the root of Glycyrrhizae uralensis, it is a selective agonist for oestrogen receptor beta. It has a role as a hormone agonist and a plant metabolite. 5-deoxyflavanone is a solid. This compound belongs to the flavanones. These are compounds containing a flavan-3-one moiety, whose structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3. MF101 is a novel estrogen receptor beta (ERβ) selective agonist and unlike currently available hormone therapies, does not activate the estrogen receptor alpha (ERα), known to be implicated in tumor formation. MF101 is an oral drug designed for the treatment of hot flashes and night sweats in peri-menopausal and menopausal women. Liquiritigenin is a natural product found in Dracaena draco, Pterocarpus marsupium, and other organisms with data available. See also: Glycyrrhiza Glabra (part of); Glycyrrhiza uralensis Root (part of); Pterocarpus marsupium wood (part of). Isolated from Glycyrrhiza, Medicago, Myroxylon, Cicer and all Leguminosae subspecies Several glycosides, particularly the rutinoside and neohesperidoside, are important in influencing citrus fruit flavour [DFC]. Liquiritigenin is found in many foods, some of which are sorrel, roselle, pepper (c. annuum), and black crowberry. Liquiritigenin is found in alfalfa. Liquiritigenin is isolated from Glycyrrhiza, Medicago, Myroxylon, Cicer, and all Leguminosae species. Several glycosides, particularly rutinoside and neohesperidoside, are important in influencing citrus fruit flavour. A dihydroxyflavanone compound having the two hydroxy substituents at the 4- and 7-positions. Isolated from the root of Glycyrrhizae uralensis, it is a selective agonist for oestrogen receptor beta. Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc. Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc.
8-Prenylnaringenin
Sophoraflavanone B is a trihydroxyflavanone that is (S)-naringenin having a prenyl group at position 8. It has a role as a platelet aggregation inhibitor and a plant metabolite. It is a trihydroxyflavanone, a member of 4-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. It is a conjugate acid of a sophoraflavanone B(1-). 8-Prenylnaringenin is a natural product found in Macaranga conifera, Macaranga denticulata, and other organisms with data available. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens A trihydroxyflavanone that is (S)-naringenin having a prenyl group at position 8. INTERNAL_ID 2299; CONFIDENCE Reference Standard (Level 1) CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2299
Kurarinone
(2S)-(-)-kurarinone is a trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2 and 4, a lavandulyl group at position 8 and a methoxy group at position 5. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. It has a role as a metabolite and an antineoplastic agent. It is a trihydroxyflavanone, a monomethoxyflavanone and a member of 4-hydroxyflavanones. It is functionally related to a (2S)-flavanone. 7,2,4-Trihydroxy-8-lavandulyl-5-methoxyflavanone is a natural product found in Albizia julibrissin, Cunila, and other organisms with data available. A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2 and 4, a lavandulyl group at position 8 and a methoxy group at position 5. Isolated from the roots of Sophora flavescens, it exhibits cytotoxicity against human myeloid leukemia HL-60 cells. Kurarinone, a flavanoid derived from shrub Sophora flavescens, inhibits the process of experimental autoimmune encephalomyelitis via blocking Th1 and Th17 cell differentiation[1]. Kurarinone, a flavanoid derived from shrub Sophora flavescens, inhibits the process of experimental autoimmune encephalomyelitis via blocking Th1 and Th17 cell differentiation[1].
Sakuranetin
Sakuranetin is a flavonoid phytoalexin that is (S)-naringenin in which the hydroxy group at position 7 is replaced by a methoxy group. It has a role as an antimycobacterial drug and a plant metabolite. It is a dihydroxyflavanone, a monomethoxyflavanone, a flavonoid phytoalexin, a member of 4-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. Sakuranetin is a natural product found in Ageratina altissima, Chromolaena odorata, and other organisms with data available. Sakuranetin is found in black walnut. Sakuranetin is a flavanone, a type of flavonoid. It can be found in Polymnia fruticosa and rice, where it acts as a phytoalexin against spore germination of Pyricularia oryzae Sakuranetin is a flavanone, a type of flavonoid. It can be found in Polymnia fruticosa and rice, where it acts as a phytoalexin against spore germination of Pyricularia oryzae. A flavonoid phytoalexin that is (S)-naringenin in which the hydroxy group at position 7 is replaced by a methoxy group. Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity[1]. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury[2]. Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity[1]. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury[2].
senegalensin
6,8-diprenylnaringenin is a trihydroxyflavanone that is (S)-naringenin substituted by prenyl groups at positions 6 and 8. It has a role as a plant metabolite and an antibacterial agent. It is a trihydroxyflavanone, a member of 4-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. Lonchocarpol A is a natural product found in Macaranga conifera, Erythrina suberosa, and other organisms with data available. A trihydroxyflavanone that is (S)-naringenin substituted by prenyl groups at positions 6 and 8.
Plantagoside
Plantagoside is a flavanone glycoside that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7, 4 and 5 and a beta-D-glucopyranosyloxy group at position 3 respectively. It has a role as a plant metabolite. It is a flavanone glycoside, a tetrahydroxyflavanone, a monosaccharide derivative, a beta-D-glucoside and a member of 4-hydroxyflavanones. It is functionally related to a (2S)-flavanone. Plantagoside is a natural product found in Plantago asiatica, Plantago major, and other organisms with data available. A flavanone glycoside that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7, 4 and 5 and a beta-D-glucopyranosyloxy group at position 3 respectively. Plantagoside, isolated from the seeds of Plantago asiatica, is a specific and non-competitive inhibitor for jack bean α-mannosidase, with an IC50 of 5 μM[1]. Plantagoside, isolated from the seeds of Plantago asiatica, is a specific and non-competitive inhibitor for jack bean α-mannosidase, with an IC50 of 5 μM[1].
Glabranin
Glabranin is a dihydroxyflavanone that is pinocembrin substituted by a prenyl group at position 8. It has a role as a plant metabolite. It is a dihydroxyflavanone and a (2S)-flavan-4-one. It is functionally related to a pinocembrin. Glabranin is a natural product found in Sophora tomentosa, Annona squamosa, and other organisms with data available. A dihydroxyflavanone that is pinocembrin substituted by a prenyl group at position 8. Saponin from licorice (Glycyrrhiza glabra). Glabranin B is found in tea and herbs and spices. Origin: Plant, Pyrans Glabranin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=41983-91-9 (retrieved 2024-07-09) (CAS RN: 41983-91-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Butin_(molecule)
Butin is a trihydroxyflavanone in which the three hydroxy substituents are located at positions 3, 4 and 7. It is found in Acacia mearnsii, Vernonia anthelmintica and Dalbergia odorifera and has a protective affect against oxidative stress-induced mitochondrial dysfunction. It has a role as an antioxidant, a protective agent and a metabolite. It is a trihydroxyflavanone and a member of 4-hydroxyflavanones. Butin is a natural product found in Dipteryx lacunifera, Acacia vestita, and other organisms with data available. A trihydroxyflavanone in which the three hydroxy substituents are located at positions 3, 4 and 7. It is found in Acacia mearnsii, Vernonia anthelmintica and Dalbergia odorifera and has a protective affect against oxidative stress-induced mitochondrial dysfunction. (-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities[1][2]. (-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities[1][2]. (-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities[1][2]. (-)-Butin is the S enantiomer of Butin. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities[1][2]. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities. Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rat[1][2]. Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities. Butin significantly alleviates myocardial infarction and improves heart function, together with prevents diabetes-induced cardiac oxidative damage in rat[1][2].
Abyssinone V
Abyssinone V is a trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7 and 4 and prenyl groups at positions 3 and 5 respectively. It has a role as a metabolite. It is a member of phenols, a trihydroxyflavanone and a member of 4-hydroxyflavanones. Abyssinone V is a natural product found in Erythrina abyssinica, Azadirachta indica, and other organisms with data available. A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7 and 4 and prenyl groups at positions 3 and 5 respectively.
Pinostrobin
A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively. Pinostrobin is a natural product found in Uvaria chamae, Zuccagnia punctata, and other organisms with data available.
Isohemiphloin
Silandrin
Constituent of Silybum marianum (milk thistle). Silandrin is found in coffee and coffee products and green vegetables. Silandrin is found in coffee and coffee products. Silandrin is a constituent of Silybum marianum (milk thistle).
Sophoranone
A dihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7 and 4 and prenyl groups at positions 3 and 5 respectively.
Abyssinone I
A monohydroxyflavanone that is (2S)-2,2-dimethyl-2,3-dihydro-2H,4H-2,6-bichromen-4-one carrying a hydroxy substituent at position 7.
Betagarin
Constituent of the leaves of sugar beet (Beta vulgaris) infected with Cercospora beticola. Betagarin is found in red beetroot, common beet, and root vegetables. Betagarin is found in common beet. Betagarin is a constituent of the leaves of sugar beet (Beta vulgaris) infected with Cercospora beticola
Pinocembrin 7-rhamnosylglucoside
A flavanone glycoside that is pinocembrin attached to a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage.
Strobopinin
A dihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5 and 7 and a methyl group at position 6 respectively.
4-Hydroxy-5,6,7-trimethoxyflavanone
A methoxyflavanone that is flavanone substituted by methoxy groups at positions 5, 6 and 7 and a hydroxy group at position 4.
5,6,7,4-Tetramethoxyflavanone
A methoxyflavanone that is flavanone substituted by methoxy groups at positions 5, 6, 7 and 4.
Hesperetin 7-glucoside
Isolated from water mint (Mentha aquatica). Hesperetin 7-glucoside is found in orange mint, herbs and spices, and green vegetables. Hesperetin 7-glucoside is found in green vegetables. Hesperetin 7-glucoside is isolated from water mint (Mentha aquatica Hesperetin 7-O-glucoside is produced by the enzymatic conversion of Hesperidin. Hesperetin 7-O-glucoside is a potent human HMG-CoA reductase inhibitor and also effectively inhibits the growth of Helicobacter pylori. Antihypertensive effect[1][2].
Sophoraflavanone G
Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways. Sophoraflavanone G. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=97938-30-2 (retrieved 2024-10-11) (CAS RN: 97938-30-2). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Flavanone
Annotation level-1 Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1]. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1].
Norartocarpanone
Norartocarpanone is a member of flavanones. Steppogenin is a natural product found in Euphorbia nicaeensis, Maclura tricuspidata, and other organisms with data available. Norartocarpanone is found in fruits. Norartocarpanone is isolated from Artocarpus incisus (breadfruit). Isolated from Artocarpus incisus (breadfruit). Norartocarpanone is found in fruits.
Dihydrooroxylin
Dihydrooroxylin A is a dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 6. Isolated from Pisonia aculeata, it exhibits antitubercular activity. It has a role as an antitubercular agent and a plant metabolite. It is a dihydroxyflavanone and a monomethoxyflavanone. Dihydrooroxylin A is a natural product found in Scutellaria scandens, Scutellaria caerulea, and other organisms with data available. A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 6. Isolated from Pisonia aculeata, it exhibits antitubercular activity. Dihydrooroxylin is found in fruits. Dihydrooroxylin is isolated from Prunus avium (wild cherry) and Piper sp. Isolated from Prunus avium (wild cherry) and Piper species Dihydrooroxylin is found in fruits.
Floribundoside
Floribundoside is found in fruits. Floribundoside occurs in Persica vulgaris (peach). Occurs in Persica vulgaris (peach). Naringenin 5-glucoside is found in fruits.
(S)-5,7-Dihydroxy-6-prenylflavanone
(S)-5,7-Dihydroxy-6-prenylflavanone is found in herbs and spices. (S)-5,7-Dihydroxy-6-prenylflavanone is a constituent of Glycyrrhiza glabra (licorice). Constituent of Glycyrrhiza glabra (licorice). (S)-5,7-Dihydroxy-6-prenylflavanone is found in tea and herbs and spices.
(S)-4',5,7-Trihydroxy-3'-prenylflavanone
(S)-4,5,7-Trihydroxy-3-prenylflavanone is found in herbs and spices. (S)-4,5,7-Trihydroxy-3-prenylflavanone is a constituent of Glycyrrhiza glabra (licorice)
Hesperetin 5-O-glucoside
Hesperetin 5-O-glucoside is found in fruits. Hesperetin 5-O-glucoside is isolated from peach (Persica vulgaris) stem bark. Isolated from peach (Persica vulgaris) stem bark. Hesperetin 5-glucoside is found in fruits and peach.
(S)-5,7-Dihydroxy-6,8-dimethylflavanone
(S)-5,7-Dihydroxy-6,8-dimethylflavanone is found in fruits. (S)-5,7-Dihydroxy-6,8-dimethylflavanone is isolated from Eugenia javanica (Java apple
Naringenin 5-rhamnoside
Naringenin 5-rhamnoside is found in fruits. Naringenin 5-rhamnoside is isolated from Prunus cerasoides (wild Himalayan cherry). Isolated from Prunus cerasoides (wild Himalayan cherry). Naringenin 5-rhamnoside is found in fruits.
Silyhermin
Constituent of Silybum marianum (milk thistle). Silyhermin is found in coffee and coffee products and green vegetables. Silyhermin is found in coffee and coffee products. Silyhermin is a constituent of Silybum marianum (milk thistle).
6'-O-Malonylnaringin
Isolated from grapefruit. Naringin 6-malonate is found in citrus and grapefruit/pummelo hybrid. 6-O-Malonylnaringin is found in citrus. 6-O-Malonylnaringin is isolated from grapefruit.
Selinone
Isolated from roots of Angelica archangelica (angelica). 4-Prenylnaringenin is found in fats and oils, herbs and spices, and green vegetables. Selinone is found in fats and oils. Selinone is isolated from roots of Angelica archangelica (angelica).
(S)-Cajaflavanone
(S)-Cajaflavanone is found in pigeon pea. (S)-Cajaflavanone is a constituent of Cajanus cajan (pigeon pea). Constituent of Cajanus cajan (pigeon pea). (S)-Cajaflavanone is found in pigeon pea and pulses.
Dihydrowogonin
Isolated from Prunus avium (wild cherry). Dihydrowogonin is found in fruits, sweet cherry, and sour cherry. Dihydrowogonin is found in fruits. Dihydrowogonin is isolated from Prunus avium (wild cherry).
6'-p-Coumaroylprunin
6-p-Coumaroylprunin is found in cashew nut. 6-p-Coumaroylprunin is isolated from Anacardium occidentale (cashew). Isolated from Anacardium occidentale (cashew). Prunin 6-p-coumarate is found in cashew nut and nuts.
5,7-Dihydroxy-4'-methoxy-8-methylflavanone
5,7-Dihydroxy-4-methoxy-8-methylflavanone is found in cereals and cereal products. 5,7-Dihydroxy-4-methoxy-8-methylflavanone is a constituent of the flowers of Amaranthus caudatus (love-lies-bleeding). Constituent of the flowers of Amaranthus caudatus (love-lies-bleeding). 5,7-Dihydroxy-4-methoxy-8-methylflavanone is found in cereals and cereal products and green vegetables.
Pinostrobin 5-glucoside
Pinostrobin 5-glucoside is found in fruits. Pinostrobin 5-glucoside is isolated from bark of morello cherry. Isolated from bark of morello cherry. Pinostrobin 5-glucoside is found in fruits.
Persiconin
Isolated from Persica vulgaris (peach) and Prunus species Persicogenin 5-glucoside is found in fruits and peach. Persiconin is found in fruits. Persiconin is isolated from Persica vulgaris (peach) and Prunus sp.
(2R)-6,8-Diglucopyranosyl-4',5,7-trihydroxyflavanone
(2S)-6,8-Diglucopyranosyl-4,5,7-trihydroxyflavanone is found in fruits. (2S)-6,8-Diglucopyranosyl-4,5,7-trihydroxyflavanone is a constituent of Zizyphus jujuba (Chinese date). Constituent of Zizyphus jujuba (Chinese date). (2R)-Naringenin 6,8-di-C-glucoside is found in fruits.
Heteroflavanone A
Heteroflavanone A is found in fruits. Heteroflavanone A is isolated from the root bark of Artocarpus heterophyllus (jackfruit). Isolated from the root bark of Artocarpus heterophyllus (jackfruit). Heteroflavanone A is found in jackfruit and fruits.
Agamanone
Agamanone is found in green vegetables. Agamanone is isolated from the famine food Agave americana. Isolated from the famine food Agave americana. Agamanone is found in green vegetables.
Heteroflavanone C
Heteroflavanone C is found in fruits. Heteroflavanone C is a constituent of the root bark of Artocarpus heterophyllus (jackfruit). Constituent of the root bark of Artocarpus heterophyllus (jackfruit). Heteroflavanone C is found in jackfruit and fruits.
Neosilyhermin A
Constituent of Silybum marianum (milk thistle). Neosilyhermin A is found in coffee and coffee products and green vegetables. Neosilyhermin B is found in coffee and coffee products. Neosilyhermin B is a constituent of Silybum marianum (milk thistle).
Glucoliquiritin apioside
Glucoliquiritin apioside is found in herbs and spices. Glucoliquiritin apioside is a constituent of Glycyrrhiza glabra (licorice). Constituent of Glycyrrhiza glabra (licorice). Neoliquiritin 4-[apiosyl-(1->2)-glucoside] is found in tea and herbs and spices.
Shinflavanone
Shinflavanone is found in herbs and spices. Shinflavanone is a constituent of Glycyrrhiza glabra (licorice). Constituent of Glycyrrhiza glabra (licorice). Shinflavanone is found in tea and herbs and spices.
Cerasinone
Isolated from Prunus cerasus (cherry). Cerasinone is found in fruits and sour cherry. Cerasinone is found in fruits. Cerasinone is isolated from Prunus cerasus (cherry).
5-Methyleriodictyol 7-[glucosyl-(1->4)-galactoside]
5-Methyleriodictyol 7-[glucosyl-(1->4)-galactoside] is found in cereals and cereal products. 5-Methyleriodictyol 7-[glucosyl-(1->4)-galactoside] is a constituent of the seeds of Fagopyrum esculentum (buckwheat). Constituent of the seeds of Fagopyrum esculentum (buckwheat). 5-Methyleriodictyol 7-[glucosyl-(1->4)-galactoside] is found in common buckwheat and cereals and cereal products.
5,7-Dihydroxy-3',4'-dimethoxy-5'-prenylflavanone
5,7-Dihydroxy-3,4-dimethoxy-5-prenylflavanone is found in herbs and spices. 5,7-Dihydroxy-3,4-dimethoxy-5-prenylflavanone is a constituent of Melilotus alba (white melilot). Constituent of Melilotus alba (white melilot). 5,7-Dihydroxy-3,4-dimethoxy-5-prenylflavanone is found in herbs and spices and pulses.
Alpinetin
Alpinetin is a phytochemical isolated from a variety of plants including those of the genus Alpinia.[1] It is going through tests to see if it is a vasorelaxant.[2] Alpinetin is a natural product found in Alpinia blepharocalyx, Alnus firma, and other organisms with data available. Alpinetin is a flavonoid isolated from cardamom and has anti-inflammatory activity. Alpinetin inhibits lipopolysaccharide (LPS)-induced inflammation, activates PPAR-γ, activates Nrf2, and inhibits TLR4 expression to protect LPS-induced renal injury[1][2]. Alpinetin is a flavonoid isolated from Alpinia katsumadai Hayata, activates activates PPAR-γ, with potent anti-inflammatory activity[1]. Alpinetin is a flavonoid isolated from Alpinia katsumadai Hayata, activates activates PPAR-γ, with potent anti-inflammatory activity[1].
Farrerol
Farrerol is an organic molecular entity. It has a role as a metabolite. (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethyl-4-benzopyrone is a natural product found in Rhododendron spinuliferum, Wikstroemia canescens, and other organisms with data available. Farrerol is a natural product found in Daphne aurantiaca, Rhododendron farrerae, and Rhododendron dauricum with data available. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6]. Farrerol is a bioactive constituent of Rhododendron, with broad activities such as anti-oxidative, anti-inflammatory, anti-tumor, neuroprotective and hepatoprotective effects[1][2][3][4][5][6].
Bavachin
Bavachin is a natural product found in Broussonetia papyrifera, Cullen corylifolium, and other organisms with data available. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
Isobavachin
Isobavachin is a member of flavanones. Isobavachin is a natural product found in Brosimum acutifolium, Erythrina sigmoidea, and other organisms with data available. Isobavachin, an antioxidant isaolated from Psoralea corylifolia with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2]. Isobavachin, an antioxidant isaolated from Psoralea corylifolia with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2].
Bavachinin
Bavachinin is a member of flavanones. Bavachinin is a natural product found in Cullen corylifolium with data available. See also: Cullen corylifolium fruit (part of). Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5]. Bavachinin is agonist of pan-peroxisome proliferator-activated receptor (PPAR), with the IC50 value of 21.043 μM, 12.819 μM, and 0.622 μM to PPAR-α, RRAR-β/δ, and PPAR-γ, respectively. Bavachinin is an inhibitor of HIF-1α. Bavachinin exhibits antitumor activity against non-small cell lung cancer by targeting RRAR-γ. Bavachinin is a natural compound with anti-inflammatory and anti-angiogenic activities. Bavachinin has orally bioactivity.[1][2][3][4][5].
Kuwanon E
Kuwanon E is a member of flavanones. 4H-1-Benzopyran-4-one, 2-(5-((2E)-3,7-dimethyl-2,6-octadienyl)-2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2S)- is a natural product found in Morus lhou, Morus mongolica, and other organisms with data available.
Isokurarinone
Isokurarinone is a natural product found in Sophora davidii and Sophora flavescens with data available.
Isosakuranin
Isosakuranin is a member of flavonoids and a glycoside. CID 102004611 is a natural product found in Prunus leveilleana, Prunus verecunda, and other organisms with data available. Isosakuranin is a natural product derived from the fruits of Paliurus ramosissimus[1].
Didymin
Didymin is a member of flavonoids and a glycoside. Didymin is a natural product found in Citrus latipes, Citrus hystrix, and other organisms with data available. See also: Tangerine peel (part of). Didymin, a dietary flavonoid glycoside from citrus fruits, possesses antioxidant properties. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma[1][2]. Didymin, a dietary flavonoid glycoside from citrus fruits, possesses antioxidant properties. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma[1][2].
5,7-Dimethoxyflavanone
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.183 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.179
Kenusanone E
Tanariflavanone B
A trihydroxyflavanone that consists of (2S)-2,3-dihydro-2H,4H-2,5-bichromen-4-one skeleton substituted by hydroxy groups at positions 5, 7 and 8, a methyl group at position 2, a prenyl group at position 6 and a 4-methylpent-3-enyl group at position 2. Isolated from Macaranga tanarius, it exhibits alleopathic effect.
5,7,4-Trihydroxy-3-methoxy-6,8-di-C-methylflavanone
7-Prenyloxy-8-C-(3-hydroxy-3-methyl-trans-buten-1-yl)flavanone
6-Prenyleriodictyol
Pinocembrin 7-O-neohesperidoside 6-O-acetate
5,4,-Dihydroxy-4,4-Dimethyl-5-[2,3:7,6]methyldihydrofuranoflavanone
4-Methylsigmoidin B
Brosimacutin C
Poriol
Poriol is a member of flavanones. Poriol is a natural product found in Pinus morrisonicola with data available. Poriol is a flavonoid isolated from Pseudotsuga sinensis[1]. Poriol is a flavonoid isolated from Pseudotsuga sinensis[1].
Ovalichromene A
Liquiritigenin 7-(3-acetylapiofuranoside)-4-glucoside
Matterionate B
Kurziflavolactone A
8-Prenyllepidissipyrone
Dorsmanin F
Naringenin 7-[3-acetyl-6-p-coumaroylglucoside]
Isoporiolide
5,7,3,4-Tetrahydroxy-6-C-methylflavanone 7-O-glucosdie
dichamanetin
A natural product found in Piper sarmentosum.
7,8,4-Trihydroxy-3,5-dimethoxyflavanone 4-O-glucoside
Kushenol B
Kushenol B is a member of flavanones. Kushenol B is a natural product found in Sophora and Sophora flavescens with data available.
Isocoreopsin
2-(3,4-Dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-4H-1-benzopyran-4-one is a natural product found in Sophora alopecuroides and Butea monosperma with data available.
Calomelanol I
Euchrestaflavanone A
Euchrestaflavanone A is a member of flavanones. Euchrestaflavanone A is a natural product found in Azadirachta indica, Erythrina subumbrans, and other organisms with data available.
Viscumneoside V
A viscumneoside that is viscumneoside III in which the primary hydroxy group of the beta-D-apiofuranosyl moiety has itself been converted to the corresponding beta-D-apiofuranoside derivative. Found in Viscum coloratum, an evergreen hemiparasitic plant whose stems and leaves are used in traditional Chinese medicine for the treatment of rheumatism.
3,4-Dihydroxy-7-methoxy-8-prenyl-5-(2-hydroxyisopropyl)-[2,3:5,6]furanoflavanone
Euchrenone a15
linderatone
Kurziflavolactone C
Viscumneoside III
A viscumneoside that is homoeriodictyol in which the hydroxy group at position 7 has been converted into the corresponding beta-D-glucopyranoside, the 2-hydroxy group of which has been converted to its beta-D-apiofuranoside derivative. Found in Viscum coloratum, an evergreen hemiparasitic plant whose stems and leaves are used in traditional Chinese medicine for the treatment of rheumatism.
Citflavanone
Euchrestaflavanone C
Lonchocarpol D1
Brosimacutin A
Calomelanol H
Euchrenone a5
5,7-Dihydroxy-8-C-(4-hydroxy-3-methyl-2-butenyl)flavanone
Sanggenon G
Sanggenon G is a member of flavanones. Sanggenon G is a natural product found in Morus alba with data available.
Lepidissipyrone
Miconioside A
Pinocembrin 7-O-neohesperidoside 3-O-acetate
7,4-Dihydroxy-8,3-dimethoxyflavanone
A dihydroxyflavanone having the two hydroxy groups located at the C-4 and -7 positions and two additional methoxy substituent at the C-3 and 8-positions.
Miconioside B
2,3-Epoxylupinifolin
Hiravanone
5,7,3-Trihydroxy-4,5-dimethoxy-6,8-di-C-methylflavanone
Louisfieserone A
Cyrtopterin
Cyrtopterin is a glycoside and a member of flavonoids.
Matteucinol 7-O-glucoside
Leachianone D
Sophoranochromene
Euchrenone a12
5-Hydroxy-7,4-dimethoxy-6,8-di-C-prenylflavanone 5-O-galactoside
Chamanetin
Lonchocarpol C1
Tephroleocarpin A
Fulvinervin A
Flemichin D
3-Methoxylupinifolin
Dereticulatin
Lophirone I
Neolinderatone
2,3-Dihydroxylupinifolin
5-Hydroxy-6-methoxy-3,4-methylenedioxyfurano[2,3:7,8]flavanone
lupinifolin
7,4-Dihydroxy-5-methoxyflavanone 7-neohesperidoside-4-glucoside
3,4-Dihydroxy-7-methoxy-8-(3-methylbut-2-enyl)-2-(1-hydroxy-1-methylethyl)-furano-(4,5:6,5)favanone
Flemiflavanone D
Euchrenone a9
5-Hydroxy-4-methoxy-6,6-dimethylpyrano[2,3:7,8]flavanone
Crotaramosmin
Amoradicin
6,8-Diprenyleriodictyol
Sophoraflavanone E
Falciformin
7,3,4-Trihydroxy-5-methoxy-6-C-methylflavanone 7-O-glucoside
5-Hydroxy-6,7,3,4,5-pentamethoxyflavanone 5-O-rhamnoside
7-Hydroxy-6,8-di-C-methylflavanone 7-O-arabinoside
5,7-Dihydroxy-4-methoxy-8-C-(2-hydroxy-3-methyl-3-butenyl)flavanone
5,7-Dihydroxy-4-methoxy-8-C-prenyl-3-(3-hydroxy-3-methylbutyl)flavanone
1-Hydroxy-2,3-Epoxylupinifolin
4-Hydroxy-5,7-dimethoxyflavanone 4-[2-(5-Cinnamoyl)-beta-D-apiofuranosyl]glucoside
4-O-Methylcarthamidin 7-(2-p-coumaroylglucoside)
Anastatin A
Isosakuranetin
4-methoxy-5,7-dihydroxyflavanone is a dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 4 (the 2S stereoisomer). It has a role as a plant metabolite. It is a dihydroxyflavanone, a monomethoxyflavanone, a member of 4-methoxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. Isosakuranetin is a natural product found in Ageratina altissima, Chromolaena odorata, and other organisms with data available. A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 4 (the 2S stereoisomer). Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia.
Burttinonedehydrate
Eriosemaone C
An extended flavonoid that consists of (2S)-flavanone substituted by hydroxy groups at positions 2, 3, and 6, a 2,4-dihyroxyphenyl group at position 5, a prenyl group at position 8 and a gem-dimethylpyran ring fused across positions 6 and 7.
Mundulea flavanone B
remangiflavanone A
A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7 and 4 and a lavandulyl group at position 8. Isolated from Physena madagascariensis, it exhibits antibacterial activity.
Spinoflavanone A
Glyflavanone A
An extended flavonoid that is 2,3-dihydro-4H,8H-pyrano[2,3-f]chromen-4-one which is substituted by a p-methoxyphenyl group at the 2-pro-S position, a methoxy group at position 5, and two methyl groups at position 8.
Exiguaflavanone A
A tetrahydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7, 2 and 6 and a lavandulyl group at position 8. Isolated from Sophora exigua and Artemisia indica, it exhibits antimalarial activity.
Sanggenol A
Sanggenol A is a natural product found in Morus cathayana and Morus alba with data available.
Epidorsmanin F
Isochamanetin
A natural product found in Piper sarmentosum.
Matteucinol
A dihydroxyflavanone that is (2S)-flavanone with hydroxy groups at positions 5 and 7, methyl groups at positions 6 and 8 and a methoxy group at position 4.
Sigmoidin B
A tetrahydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7, 3 and 4 and a prenyl group at position 5. Isolated from Erythrina sigmoidea, it exhibits anti-inflammatory and antioxidant activities.
Minimiflorin
Eriocitrin
Eriocitrin is a disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant. It is a disaccharide derivative, a member of 3-hydroxyflavanones, a trihydroxyflavanone, a flavanone glycoside, a member of 4-hydroxyflavanones and a rutinoside. It is functionally related to an eriodictyol. Eriocitrin is a natural product found in Cyclopia subternata, Citrus latipes, and other organisms with data available. A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. Eriocitrin is a flavonoid isolated from lemon, which is a strong antioxidant agent. Eriocitrin could inhibit the proliferation of hepatocellular carcinoma cell lines by arresting cell cycle in S phase through up-regulation of p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating mitochondria-involved intrinsic signaling pathway[1]. Eriocitrin is a flavonoid isolated from lemon, which is a strong antioxidant agent. Eriocitrin could inhibit the proliferation of hepatocellular carcinoma cell lines by arresting cell cycle in S phase through up-regulation of p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating mitochondria-involved intrinsic signaling pathway[1].
Licorice glycoside E
Liquiritin apioside
Liquiritin apioside, a main flavonoid component of licorice, possesses antitussive effects[1]. Liquiritin apioside, a main flavonoid component of licorice, possesses antitussive effects[1].
Liquiritin
Liquiritin is a flavanone glycoside that is liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. It has a role as a plant metabolite, an anticoronaviral agent and an anti-inflammatory agent. It is a flavanone glycoside, a beta-D-glucoside, a monosaccharide derivative and a monohydroxyflavanone. It is functionally related to a liquiritigenin. Liquiritin is a natural product found in Polygonum aviculare, Artemisia capillaris, and other organisms with data available. See also: Glycyrrhiza Glabra (part of); Glycyrrhiza uralensis Root (part of). A flavanone glycoside that is liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage. Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.697 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.694 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.693 Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2]. Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2]. Neoliquiritin is isolated from Glycyrrhiza uralensis with an anti-inflammatory activity[1]. Neoliquiritin is isolated from Glycyrrhiza uralensis with an anti-inflammatory activity[1].
5,7,3-Trihydroxy-4-methoxyflavanone 7-(2,6-dirhamnosylglucoside)
Prunin
Naringenin 7-O-beta-D-glucoside is a flavanone 7-O-beta-D-glucoside that is (S)-naringenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a metabolite, a hypoglycemic agent, an antilipemic drug and an antibacterial agent. It is a flavanone 7-O-beta-D-glucoside, a dihydroxyflavanone, a monosaccharide derivative, a member of 4-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. Prunin is a natural product found in Prunus mume, Podocarpus nivalis, and other organisms with data available. A flavanone 7-O-beta-D-glucoside that is (S)-naringenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 5.5 μM[1][2]. Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 5.5 μM[1][2].
Sigmoidin F
Flavanomarein
Acquisition and generation of the data is financially supported in part by CREST/JST. Flavanomarein is a natural product found in Abies pindrow with data available. Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities[1][2].
Oprea1_401356
7-hydroxyflavanone is a monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 7. 7-Hydroxyflavanone is a natural product found in Dalbergia cochinchinensis, Berberis dictyota, and other organisms with data available.
Neohesperidin dihydrochalcone
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2814 Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener. Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener.
Eriodictyol-7-glucoside
Acquisition and generation of the data is financially supported in part by CREST/JST. Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity[1]. Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity[1].
(2S)-8-[(E)-3-hydroxy-3-methylbut-1-enyl]-5,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one
Nymphaeol C
A tetrahydroxyflavanone that is (2S)-flavanone substituted by hydroxy group at positions 5, 7, 3 and 4, a geranyl group at position 2 and a prenyl group at position 6. Isolated from Macaranga tanarius and propolis collected in Okinawa, it exhibits radical scavenging activity.
