Cytoplasm |
11 |
ADAM10, BCL2L1, CASP3, DCX, DLG4, MAPT, NES, NOX4, PCSK9, PROX1, SIRT1 |
Golgi apparatus, trans-Golgi network membrane |
1 |
DLG4 |
Peripheral membrane protein |
1 |
MAPT |
Endosome membrane |
2 |
BACE1, LDLR |
Endoplasmic reticulum membrane |
2 |
NOX4, PSEN1 |
Mitochondrion membrane |
1 |
BCL2L1 |
Nucleus |
7 |
ADAM10, CASP3, MAPT, NOX4, PROX1, PSEN1, SIRT1 |
cytosol |
7 |
BCL2L1, CASP3, DCX, DLG4, MAPT, PROX1, SIRT1 |
dendrite |
4 |
ADAM10, BACE1, MAPT, PSEN1 |
trans-Golgi network |
1 |
BACE1 |
centrosome |
2 |
BCL2L1, PSEN1 |
nucleoplasm |
4 |
CASP3, PROX1, PSEN1, SIRT1 |
Cell membrane |
8 |
ADAM10, BACE1, DLG4, LDLR, MAPT, NOX1, NOX4, PSEN1 |
Lipid-anchor |
1 |
DLG4 |
Cytoplasmic side |
3 |
BCL2L1, DLG4, MAPT |
Cell projection, axon |
5 |
ADAM10, BACE1, DLG4, MAPT, PSEN1 |
Cell projection, growth cone |
1 |
PSEN1 |
Cytoplasmic granule |
1 |
PSEN1 |
Early endosome membrane |
2 |
DLG4, PSEN1 |
Multi-pass membrane protein |
4 |
NOX1, NOX4, PSEN1, SYP |
Golgi apparatus membrane |
3 |
ADAM10, DLG4, PSEN1 |
Synapse |
2 |
DLG4, PSEN1 |
cell cortex |
1 |
PSEN1 |
cell junction |
2 |
DLG4, PSEN1 |
cell surface |
5 |
ADAM10, BACE1, LDLR, PCSK9, PSEN1 |
ciliary rootlet |
1 |
PSEN1 |
dendritic shaft |
1 |
PSEN1 |
gamma-secretase complex |
1 |
PSEN1 |
glutamatergic synapse |
5 |
ADAM10, CASP3, DCX, DLG4, PSEN1 |
Golgi apparatus |
5 |
ADAM10, BACE1, LDLR, PCSK9, PSEN1 |
Golgi membrane |
3 |
ADAM10, DLG4, PSEN1 |
growth cone |
2 |
MAPT, PSEN1 |
lysosomal membrane |
2 |
PCSK9, PSEN1 |
mitochondrial inner membrane |
2 |
BCL2L1, PSEN1 |
neuromuscular junction |
3 |
DLG4, PSEN1, SYP |
neuronal cell body |
4 |
BACE1, CASP3, MAPT, PSEN1 |
postsynapse |
1 |
PSEN1 |
presynaptic membrane |
2 |
PSEN1, SYP |
sarcolemma |
1 |
PSEN1 |
smooth endoplasmic reticulum |
1 |
PSEN1 |
synaptic vesicle |
4 |
BACE1, DLG4, PSEN1, SYP |
Cytoplasm, cytosol |
2 |
BCL2L1, MAPT |
Lysosome |
3 |
BACE1, LDLR, PCSK9 |
Presynapse |
1 |
DLG4 |
endosome |
2 |
BACE1, PCSK9 |
plasma membrane |
9 |
ADAM10, BACE1, DLG4, LDLR, MAPT, NOX1, NOX4, PCSK9, PSEN1 |
presynaptic active zone |
1 |
SYP |
synaptic vesicle membrane |
2 |
BCL2L1, SYP |
terminal bouton |
1 |
SYP |
Membrane |
7 |
ADAM10, BACE1, LDLR, NOX1, NOX4, PSEN1, SYP |
axon |
5 |
ADAM10, BACE1, DLG4, MAPT, PSEN1 |
basolateral plasma membrane |
2 |
DLG4, LDLR |
extracellular exosome |
1 |
ADAM10 |
endoplasmic reticulum |
6 |
BACE1, BCL2L1, DLG4, NOX4, PCSK9, PSEN1 |
extracellular space |
1 |
PCSK9 |
perinuclear region of cytoplasm |
3 |
NOX4, PCSK9, SYP |
Schaffer collateral - CA1 synapse |
1 |
SYP |
adherens junction |
2 |
ADAM10, DLG4 |
mitochondrion |
5 |
BCL2L1, MAPT, NOX4, PSEN1, SIRT1 |
protein-containing complex |
1 |
PSEN1 |
intracellular membrane-bounded organelle |
1 |
ADAM10 |
postsynaptic density |
3 |
ADAM10, CASP3, DLG4 |
chromatin silencing complex |
1 |
SIRT1 |
Single-pass type I membrane protein |
3 |
ADAM10, BACE1, LDLR |
Secreted |
2 |
MAPT, PCSK9 |
extracellular region |
2 |
MAPT, PCSK9 |
Mitochondrion outer membrane |
1 |
BCL2L1 |
Single-pass membrane protein |
2 |
BCL2L1, LDLR |
mitochondrial outer membrane |
1 |
BCL2L1 |
excitatory synapse |
2 |
DLG4, SYP |
hippocampal mossy fiber to CA3 synapse |
1 |
BACE1 |
Mitochondrion matrix |
1 |
BCL2L1 |
mitochondrial matrix |
1 |
BCL2L1 |
anchoring junction |
1 |
NOX1 |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
1 |
BCL2L1 |
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane |
2 |
BCL2L1, SYP |
Nucleus membrane |
1 |
BCL2L1 |
Bcl-2 family protein complex |
1 |
BCL2L1 |
nuclear membrane |
2 |
BCL2L1, PSEN1 |
external side of plasma membrane |
1 |
LDLR |
low-density lipoprotein particle |
1 |
LDLR |
multivesicular body |
1 |
BACE1 |
dendritic spine |
2 |
DLG4, MAPT |
microtubule cytoskeleton |
1 |
MAPT |
nucleolus |
2 |
NOX4, SIRT1 |
axon cytoplasm |
1 |
MAPT |
neuron spine |
1 |
DLG4 |
Early endosome |
5 |
BACE1, LDLR, NOX1, PCSK9, PSEN1 |
Membrane, clathrin-coated pit |
1 |
LDLR |
apical part of cell |
1 |
LDLR |
clathrin-coated pit |
1 |
LDLR |
COPII-coated ER to Golgi transport vesicle |
1 |
PCSK9 |
Golgi-associated vesicle |
1 |
ADAM10 |
recycling endosome |
1 |
BACE1 |
postsynaptic membrane |
1 |
DLG4 |
Cytoplasm, perinuclear region |
1 |
NOX4 |
heterochromatin |
1 |
SIRT1 |
Membrane raft |
3 |
BACE1, MAPT, PSEN1 |
pore complex |
1 |
ADAM10 |
Cell junction, focal adhesion |
1 |
NOX4 |
Cytoplasm, cytoskeleton |
2 |
DLG4, MAPT |
focal adhesion |
2 |
ADAM10, NOX4 |
microtubule |
2 |
DCX, MAPT |
axolemma |
1 |
MAPT |
Cell junction, adherens junction |
1 |
ADAM10 |
Cell projection, dendritic spine |
1 |
DLG4 |
Nucleus, PML body |
1 |
SIRT1 |
PML body |
1 |
SIRT1 |
intermediate filament |
1 |
NES |
nuclear speck |
1 |
MAPT |
nuclear inner membrane |
1 |
SIRT1 |
nuclear outer membrane |
1 |
PSEN1 |
dendrite cytoplasm |
1 |
DLG4 |
Late endosome |
3 |
BACE1, LDLR, PCSK9 |
receptor complex |
1 |
LDLR |
Cell projection, neuron projection |
2 |
DCX, PSEN1 |
neuron projection |
5 |
DCX, DLG4, MAPT, PSEN1, SYP |
chromatin |
2 |
PROX1, SIRT1 |
microtubule associated complex |
1 |
DCX |
cell projection |
1 |
NOX1 |
cytoskeleton |
2 |
DCX, DLG4 |
cytoplasmic ribonucleoprotein granule |
1 |
MAPT |
[Isoform 5]: Cytoplasm |
1 |
NOX4 |
Golgi apparatus, trans-Golgi network |
1 |
BACE1 |
Nucleus, nucleolus |
1 |
NOX4 |
fibrillar center |
1 |
SIRT1 |
nuclear envelope |
1 |
SIRT1 |
Endomembrane system |
3 |
BACE1, LDLR, SYP |
sorting endosome |
1 |
LDLR |
Cytoplasmic vesicle membrane |
1 |
BACE1 |
AMPA glutamate receptor complex |
1 |
DLG4 |
Cell projection, dendrite |
4 |
ADAM10, BACE1, DLG4, MAPT |
specific granule membrane |
1 |
ADAM10 |
tertiary granule membrane |
1 |
ADAM10 |
euchromatin |
1 |
SIRT1 |
cell body |
1 |
MAPT |
intermediate filament cytoskeleton |
1 |
NES |
[Isoform 3]: Cytoplasm |
1 |
NOX4 |
clathrin-coated vesicle |
1 |
ADAM10 |
synaptic membrane |
2 |
ADAM10, DLG4 |
trans-Golgi network membrane |
1 |
DLG4 |
endoplasmic reticulum lumen |
3 |
ADAM10, BACE1, PCSK9 |
cortical actin cytoskeleton |
1 |
DLG4 |
kinetochore |
1 |
PSEN1 |
endocytic vesicle membrane |
1 |
DLG4 |
Cytoplasmic vesicle, clathrin-coated vesicle |
1 |
ADAM10 |
azurophil granule membrane |
1 |
PSEN1 |
cerebellar mossy fiber |
1 |
DLG4 |
postsynaptic density membrane |
1 |
DLG4 |
aggresome |
1 |
PSEN1 |
perinuclear endoplasmic reticulum |
2 |
ADAM10, NOX4 |
tetraspanin-enriched microdomain |
1 |
ADAM10 |
clathrin-coated endocytic vesicle membrane |
1 |
LDLR |
Synapse, synaptosome |
1 |
SYP |
endolysosome membrane |
2 |
LDLR, PCSK9 |
death-inducing signaling complex |
1 |
CASP3 |
eNoSc complex |
1 |
SIRT1 |
rDNA heterochromatin |
1 |
SIRT1 |
Rough endoplasmic reticulum |
1 |
PSEN1 |
somatodendritic compartment |
2 |
LDLR, MAPT |
extrinsic component of external side of plasma membrane |
1 |
PCSK9 |
nuclear periphery |
1 |
MAPT |
[Isoform 4]: Nucleus |
1 |
NOX4 |
glial cell projection |
1 |
MAPT |
PCSK9-LDLR complex |
2 |
LDLR, PCSK9 |
cortical cytoskeleton |
1 |
DLG4 |
NADPH oxidase complex |
2 |
NOX1, NOX4 |
Cell projection, invadopodium membrane |
1 |
NOX1 |
neurofibrillary tangle |
1 |
MAPT |
PCSK9-AnxA2 complex |
1 |
PCSK9 |
neuron projection terminus |
1 |
DLG4 |
main axon |
1 |
MAPT |
tubulin complex |
1 |
MAPT |
[Isoform 6]: Cytoplasm |
1 |
NOX4 |
juxtaparanode region of axon |
1 |
DLG4 |
Golgi-associated vesicle lumen |
1 |
BACE1 |
[Isoform Bcl-X(L)]: Mitochondrion inner membrane |
1 |
BCL2L1 |
Golgi cis cisterna |
1 |
DLG4 |
[SirtT1 75 kDa fragment]: Cytoplasm |
1 |
SIRT1 |