Abyssinone V (BioDeep_00000001039)
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C25H28O5 (408.1937)
中文名称:
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 82.61%
分子结构信息
SMILES: C1(O)C=C2O[C@]([H])(C3C=C(C/C=C(\C)/C)C(O)=C(C/C=C(\C)/C)C=3)CC(=O)C2=C(O)C=1
InChI: InChI=1S/C25H28O5/c1-14(2)5-7-16-9-18(10-17(25(16)29)8-6-15(3)4)22-13-21(28)24-20(27)11-19(26)12-23(24)30-22/h5-6,9-12,22,26-27,29H,7-8,13H2,1-4H3/t22-/m0/s1
描述信息
Abyssinone V is a trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7 and 4 and prenyl groups at positions 3 and 5 respectively. It has a role as a metabolite. It is a member of phenols, a trihydroxyflavanone and a member of 4-hydroxyflavanones.
Abyssinone V is a natural product found in Erythrina abyssinica, Azadirachta indica, and other organisms with data available.
A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7 and 4 and prenyl groups at positions 3 and 5 respectively.
同义名列表
13 个代谢物同义名
4H-1-Benzopyran-4-one, {2,3-Dihydro-5,7-dihydroxy-2-[4-hydroxy-3,} 5-bis(3-methyl-2-butenyl)phenyl]-, (S)-; 4H-1-Benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-[4-hydroxy-3,5-bis(3-methyl-2-buten-1-yl)phenyl]-,(2S)-; (2S)-5,7-dihydroxy-2-[4-hydroxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl]-2,3-dihydro-4H-chromen-4-one; (2S)-5,7-dihydroxy-2-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]-2,3-dihydrochromen-4-one; 5,7-Dihydroxy-2-(4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl)-2,3-dihydro-4H-chromen-4-one; (2S)-5,7-dihydroxy-2-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]chroman-4-one; MEGxp0_000009; ACon0_000344; abyssinone-V; Abyssinone V; ACon1_000328; 5,7-dihydroxy-2-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]-2,3-dihydrochromen-4-one; Abyssinone V
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:2368
- KEGG: C09319
- PubChem: 442153
- PubChem: 101203
- Metlin: METLIN52759
- ChEMBL: CHEMBL255890
- LipidMAPS: LMPK12140275
- MeSH: abyssinone V
- CAS: 77263-11-7
- medchemexpress: HY-N8265
- PMhub: MS000020615
- MetaboLights: MTBLC2368
- PubChem: 11510
- KNApSAcK: C00000936
- 3DMET: B02859
- NIKKAJI: J869.483D
- RefMet: Abyssinone V
- KNApSAcK: 2368
- LOTUS: LTS0167183
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
53 个相关的物种来源信息
- 124942 - Azadirachta: LTS0167183
- 124943 - Azadirachta indica: 10.1021/JF034666Z
- 124943 - Azadirachta indica: LTS0167183
- 3841 - Erythrina: LTS0167183
- 1237573 - Erythrina abyssinica:
- 1237573 - Erythrina abyssinica: 10.1016/S0031-9422(00)00349-6
- 1237573 - Erythrina abyssinica: 10.1021/NP070506W
- 1237573 - Erythrina abyssinica: 10.1021/NP50019A002
- 1237573 - Erythrina abyssinica: 10.1021/NP960440X
- 1237573 - Erythrina abyssinica: LTS0167183
- 2590682 - Erythrina addisoniae:
- 2590682 - Erythrina addisoniae: 10.1016/S0031-9422(00)00349-6
- 2590682 - Erythrina addisoniae: 10.1021/NP070417J
- 2590682 - Erythrina addisoniae: 10.1021/NP070506W
- 2590682 - Erythrina addisoniae: LTS0167183
- 2590687 - Erythrina burttii: 10.1016/S0031-9422(97)00945-X
- 2590687 - Erythrina burttii: LTS0167183
- 3844 - Erythrina latissima:
- 3844 - Erythrina latissima: 10.1016/S0031-9422(00)00349-6
- 3844 - Erythrina latissima: 10.1016/S0367-326X(00)00142-8
- 3844 - Erythrina latissima: 10.1021/NP070506W
- 3844 - Erythrina latissima: LTS0167183
- 2708827 - Erythrina mildbraedii: 10.1021/NP0601861
- 2708827 - Erythrina mildbraedii: LTS0167183
- 1899109 - Erythrina sacleuxii:
- 1899109 - Erythrina sacleuxii: 10.1016/S0031-9422(00)00349-6
- 1899109 - Erythrina sacleuxii: 10.1021/NP070506W
- 1899109 - Erythrina sacleuxii: LTS0167183
- 1977555 - Erythrina sigmoidea:
- 1977555 - Erythrina sigmoidea: 10.1016/S0031-9422(00)00349-6
- 1977555 - Erythrina sigmoidea: 10.1021/NP070506W
- 1977555 - Erythrina sigmoidea: 10.1021/NP50057A034
- 1977555 - Erythrina sigmoidea: 10.1021/NP50062A017
- 1977555 - Erythrina sigmoidea: 10.3987/S-1981-02-1163
- 1977555 - Erythrina sigmoidea: LTS0167183
- 1288014 - Erythrina subumbrans: 10.1021/NP070506W
- 1288014 - Erythrina subumbrans: LTS0167183
- 33682 - Euglenozoa: LTS0167183
- 2759 - Eukaryota: LTS0167183
- 3803 - Fabaceae: LTS0167183
- 5653 - Kinetoplastea: LTS0167183
- 37500 - Maackia: LTS0167183
- 37501 - Maackia amurensis: 10.1248/CPB.57.302
- 37501 - Maackia amurensis: LTS0167183
- 3398 - Magnoliopsida: LTS0167183
- 43707 - Meliaceae: LTS0167183
- 35493 - Streptophyta: LTS0167183
- 58023 - Tracheophyta: LTS0167183
- 5690 - Trypanosoma: LTS0167183
- 5691 - Trypanosoma brucei: 10.1128/AAC.00044-13
- 5691 - Trypanosoma brucei: LTS0167183
- 5654 - Trypanosomatidae: LTS0167183
- 33090 - Viridiplantae: LTS0167183
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Karoline Koch, Gabriel Schulz, Wera Döring, Christian Büchter, Susannah Havermann, Patrick Chalo Mutiso, Claus Passreiter, Wim Wätjen. Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans.
The Journal of pharmacy and pharmacology.
2019 Jun; 71(6):1007-1016. doi:
10.1111/jphp.13074. [PMID: 30793315] - Stephen S Nyandoro, Joan J E Munissi, Msim Kombo, Clarence A Mgina, Fangfang Pan, Amra Gruhonjic, Paul Fitzpatrick, Yu Lu, Bin Wang, Kari Rissanen, Máté Erdélyi. Flavonoids from Erythrina schliebenii.
Journal of natural products.
2017 02; 80(2):377-383. doi:
10.1021/acs.jnatprod.6b00839. [PMID: 28112509] - Marie A Mvondo, Dieudonné Njamen, Georg Kretzschmar, Manuela Imma Bader, Stephen Tanee Fomum, Jean Wandji, Günter Vollmer. Alpinumisoflavone and abyssinone V 4'-methylether derived from Erythrina lysistemon (Fabaceae) promote HDL-cholesterol synthesis and prevent cholesterol gallstone formation in ovariectomized rats.
The Journal of pharmacy and pharmacology.
2015 Jul; 67(7):990-6. doi:
10.1111/jphp.12386. [PMID: 25683903] - Dieudonné Njamen, Marie Alfrede Mvondo, Telesphore Nanbo Gueyo, Stéphane Zingue, Stephen Tanee Fomum, Jean Wandji. Erythrina lysistemon-derived flavonoids account only in part for the plant's specific effects on rat uterus and vagina.
Journal of basic and clinical physiology and pharmacology.
2015 May; 26(3):287-94. doi:
10.1515/jbcpp-2014-0034. [PMID: 25153589] - M A Mvondo, D Njamen, S Tanee Fomum, J Wandji. Effects of alpinumisoflavone and abyssinone V-4'-methyl ether derived from Erythrina lysistemon (Fabaceae) on the genital tract of ovariectomized female Wistar rat.
Phytotherapy research : PTR.
2012 Jul; 26(7):1029-36. doi:
10.1002/ptr.3685. [PMID: 22183714] - Phi Hung Nguyen, Trong Tuan Dao, Jayeon Kim, Do Tuan Phong, Derek Tantoh Ndinteh, Joseph Tanyi Mbafor, Won Keun Oh. New 5-deoxyflavonoids and their inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) activity.
Bioorganic & medicinal chemistry.
2011 Jun; 19(11):3378-83. doi:
10.1016/j.bmc.2011.04.037. [PMID: 21571537] - W Wätjen, A K Suckow-Schnitker, R Rohrig, A Kulawik, J Addae-Kyereme, C W Wright, C M Passreiter. Prenylated flavonoid derivatives from the bark of Erythrina addisoniae.
Journal of natural products.
2008 Apr; 71(4):735-8. doi:
10.1021/np070417j. [PMID: 18302333] - Thitima Rukachaisirikul, Phongsak Innok, Apichart Suksamrarn. Erythrina alkaloids and a pterocarpan from the bark of Erythrina subumbrans.
Journal of natural products.
2008 Jan; 71(1):156-8. doi:
10.1021/np070506w. [PMID: 18171023] - MinKyun Na, JunPil Jang, Dieudonné Njamen, Joseph Tanyi Mbafor, Zacharias Tanee Fomum, Bo Yeon Kim, Won Keun Oh, Jong Seog Ahn. Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii.
Journal of natural products.
2006 Nov; 69(11):1572-6. doi:
10.1021/np0601861. [PMID: 17125223] - Kazuhiko Nakahara, Molay Kumar Roy, Hiroshi Ono, Ikuko Maeda, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Gassinee Trakoontivakorn. Prenylated flavanones isolated from flowers of Azadirachta indica (the neem tree) as antimutagenic constituents against heterocyclic amines.
Journal of agricultural and food chemistry.
2003 Oct; 51(22):6456-60. doi:
10.1021/jf034666z. [PMID: 14558762] - M Taniguchi, I Kubo. Ethnobotanical drug discovery based on medicine men's trials in the African savanna: screening of east African plants for antimicrobial activity II.
Journal of natural products.
1993 Sep; 56(9):1539-46. doi:
10.1021/np50099a012. [PMID: 8254349] - R Promsattha, M S Tempesta, Z T Fomum, J T Mbafor. (-)-Sigmoidin E: a new prenylated flavonoid from Erythrina sigmoidea.
Journal of natural products.
1988 May; 51(3):611-3. doi:
10.1021/np50057a034. [PMID: 3404157]
