Isobavachin (BioDeep_00000229960)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(2S)-7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one

化学式: C20H20O4 (324.1362)
中文名称: 异补骨脂二氢黄酮, 异补骨脂黄酮
谱图信息: 最多检出来源 Viridiplantae(plant) 79.09%

Reviewed

Last reviewed on 2024-10-24.

Cite this Page

Isobavachin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/isobavachin (retrieved 2025-01-30) (BioDeep RN: BioDeep_00000229960). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1(O)=C(C/C=C(\C)/C)C2OC(C3C=CC(O)=CC=3)CC(=O)C=2C=C1
InChI: InChI=1S/C20H20O4/c1-12(2)3-8-15-17(22)10-9-16-18(23)11-19(24-20(15)16)13-4-6-14(21)7-5-13/h3-7,9-10,19,21-22H,8,11H2,1-2H3

描述信息

Isobavachin is a member of flavanones.
Isobavachin is a natural product found in Brosimum acutifolium, Erythrina sigmoidea, and other organisms with data available.
Isobavachin, an antioxidant isaolated from Psoralea corylifolia with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2].
Isobavachin, an antioxidant isaolated from Psoralea corylifolia with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2].

同义名列表

5 个代谢物同义名

7-Hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-1-benzopyran-4-one; (2S)-7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one; 4,7-dihydroxy-8-prenylflavanone; Isobavachin; (S) -2,3-Dihydro-7-hydroxy-2- (4-hydroxyphenyl) -8- (3-methyl-2-butenyl) -4H-1-benzopyran-4-one



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

36 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Rene Barbie Browne, Nabajyoti Goswami, Probodh Borah, Jayanti Datta Roy. Computational approaches for evaluation of isobavachin as potential inhibitor against t877a and w741l mutations in prostate cancer. Journal of biomolecular structure & dynamics. 2023 04; 41(6):2398-2418. doi: 10.1080/07391102.2022.2032353. [PMID: 35118933]
  • Jia-Jun Luo, Xin-Hua Chen, Peng-Ying Liang, Zean Zhao, Ting Wu, Zhong-Huang Li, Shan-He Wan, Jian Luo, Jian-Xin Pang, Jia-Jie Zhang, Yuan-Xin Tian. Mechanism of anti-hyperuricemia of isobavachin based on network pharmacology and molecular docking. Computers in biology and medicine. 2023 Feb; 155(?):106637. doi: 10.1016/j.compbiomed.2023.106637. [PMID: 36791549]
  • Han Xing, Jing Yang, Kaidi Ren, Zifei Qin, Peile Wang, Xiaojian Zhang, Zhihong Yao, Frank J Gonzalez, Xinsheng Yao. Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu-gu-zhi) and its potential inhibition against human cytochrome P450s and UDP-glucuronosyltransferases. The Journal of pharmacy and pharmacology. 2020 Dec; 72(12):1865-1878. doi: 10.1111/jphp.13337. [PMID: 32750744]
  • Zhi-Xing Zhou, Li Yang, Li-Yuan Cheng, Ying-Li Yu, Lei Song, Kun Zhou, Ying-Liang Wu, Yue Zhang. Simultaneous characterization of multiple Psoraleae Fructus bioactive compounds in rat plasma by ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry for application in sex-related differences in pharmacokinetics. Journal of separation science. 2020 Jul; 43(14):2804-2816. doi: 10.1002/jssc.202000286. [PMID: 32384213]
  • Jaeyoung Kwon, Sunita Basnet, Jin Woo Lee, Eun-Kyoung Seo, Nanzad Tsevegsuren, Bang Yeon Hwang, Dongho Lee. Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages. Bioorganic & medicinal chemistry letters. 2015 Aug; 25(16):3314-8. doi: 10.1016/j.bmcl.2015.05.062. [PMID: 26073007]
  • Muhammad Shaiq Ali, Muhammad Imran Ali, Patricia A Onocha, Zeeshan Ahmed. bis-Sigmodiol: a new prenylflavanone dimer from Erythrina sigmoidea Hua (Fabaceae) of Nigeria. Journal of Asian natural products research. 2011 Feb; 13(2):182-7. doi: 10.1080/10286020.2010.546352. [PMID: 21279883]
  • Maya Mori-Hongo, Hiromi Yamaguchi, Tsutomu Warashina, Toshio Miyase. Melanin synthesis inhibitors from Lespedeza cyrtobotrya. Journal of natural products. 2009 Jan; 72(1):63-71. doi: 10.1021/np800535g. [PMID: 19102656]
  • Hiroyuki Haraguchi, Junji Inoue, Yukiyoshi Tamura, Kenji Mizutani. Antioxidative components of Psoralea corylifolia (Leguminosae). Phytotherapy research : PTR. 2002 Sep; 16(6):539-44. doi: 10.1002/ptr.972. [PMID: 12237811]