Oprea1_401356 (BioDeep_00000397436)

 

Secondary id: BioDeep_00000009813

PANOMIX_OTCML-2023


代谢物信息卡片


4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-phenyl-

化学式: C15H12O3 (240.0786)
中文名称: 7-羟基黄烷酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(ccc2c(c1)O[C@@H](CC2=O)c1ccccc1)O
InChI: InChI=1S/C15H12O3/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-8,14,16H,9H2

描述信息

7-hydroxyflavanone is a monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 7.
7-Hydroxyflavanone is a natural product found in Dalbergia cochinchinensis, Berberis dictyota, and other organisms with data available.

同义名列表

15 个代谢物同义名

4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-phenyl-; 2,3-dihydro-7-hydroxy-2-phenyl-4H-1-benzopyran-4-one; 7-hydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one; 7-hydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one; 7-hydroxy-2-phenyl-2,3-dihydrochromen-4-one; 7-Hydroxy-2-phenylchroman-4-one; 7-hydroxy-2-phenyl-4-chromanone; 7-Hydroxyflavanone, 98\\%; 2H-1-Benzopyran-7-yloxy; FLAVANONE, 7-HYDROXY-; 7-hydroxy-flavanone; 7-Hydroxyflavanone; UNII:CC64495H41; Oprea1_401356; 7-Hydroxyflavanone



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ANXA5, CASP3, CASP7, ELAVL1, IL13, PTGS2
Peripheral membrane protein 3 ANXA5, CYP1B1, PTGS2
Endoplasmic reticulum membrane 7 CYP19A1, CYP1B1, PTGS2, UGT1A1, UGT1A7, UGT1A8, UGT1A9
Nucleus 3 CASP3, CASP7, ELAVL1
cytosol 5 ANXA5, CASP3, CASP7, ELAVL1, GPT
nucleoplasm 4 CASP3, CASP7, CD2, ELAVL1
Cell membrane 1 CD2
Multi-pass membrane protein 1 CYP19A1
cell surface 1 CD2
glutamatergic synapse 2 CASP3, ELAVL1
Golgi apparatus 1 CD2
neuronal cell body 1 CASP3
postsynapse 1 ELAVL1
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 CASP7
plasma membrane 2 CD2, UGT1A1
Membrane 8 ANXA5, CYP19A1, CYP1B1, ELAVL1, UGT1A1, UGT1A7, UGT1A8, UGT1A9
caveola 1 PTGS2
extracellular exosome 2 ANXA5, GPT
endoplasmic reticulum 7 CYP19A1, ELAVL1, PTGS2, UGT1A1, UGT1A7, UGT1A8, UGT1A9
extracellular space 4 CASP7, IL13, IL6, TIMP2
perinuclear region of cytoplasm 1 UGT1A1
mitochondrion 1 CYP1B1
protein-containing complex 2 CD2, PTGS2
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 3 CYP19A1, CYP1B1, PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 CD2
Secreted 3 IL13, IL6, TIMP2
extracellular region 5 ANXA5, CD2, IL13, IL6, TIMP2
cytoplasmic side of plasma membrane 1 CD2
Single-pass membrane protein 4 UGT1A1, UGT1A7, UGT1A8, UGT1A9
external side of plasma membrane 3 ANXA5, CD2, IL13
cytoplasmic vesicle 1 ELAVL1
sarcoplasm 1 ELAVL1
Cytoplasm, P-body 1 ELAVL1
P-body 1 ELAVL1
cell-cell junction 1 CD2
Cytoplasm, perinuclear region 1 UGT1A1
focal adhesion 1 ANXA5
extracellular matrix 1 TIMP2
collagen-containing extracellular matrix 2 ANXA5, TIMP2
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Zymogen granule membrane 1 ANXA5
neuron projection 1 PTGS2
Secreted, extracellular space 1 CASP7
Cytoplasm, Stress granule 1 ELAVL1
cytoplasmic stress granule 1 ELAVL1
ficolin-1-rich granule lumen 1 TIMP2
endoplasmic reticulum lumen 2 IL6, PTGS2
specific granule lumen 1 TIMP2
tertiary granule lumen 1 TIMP2
vesicle membrane 1 ANXA5
ribonucleoprotein complex 1 ELAVL1
death-inducing signaling complex 1 CASP3
interleukin-6 receptor complex 1 IL6
endoplasmic reticulum chaperone complex 1 UGT1A1
endothelial microparticle 1 ANXA5
cytochrome complex 1 UGT1A1


文献列表

  • Tsegaye Deyou, Ivan Gumula, Fangfang Pang, Amra Gruhonjic, Michael Mumo, John Holleran, Sandra Duffy, Paul A Fitzpatrick, Matthias Heydenreich, Göran Landberg, Solomon Derese, Vicky Avery, Kari Rissanen, Máté Erdélyi, Abiy Yenesew. Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis. Journal of natural products. 2015 Dec; 78(12):2932-9. doi: 10.1021/acs.jnatprod.5b00581. [PMID: 26651537]
  • Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. Toxicological sciences : an official journal of the Society of Toxicology. 2015 Feb; 143(2):333-48. doi: 10.1093/toxsci/kfu231. [PMID: 25349334]
  • Huixiao Hong, William S Branham, Stacey L Dial, Carrie L Moland, Hong Fang, Jie Shen, Roger Perkins, Daniel Sheehan, Weida Tong. Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities. Chemical research in toxicology. 2012 Nov; 25(11):2553-66. doi: 10.1021/tx3003406. [PMID: 23013281]
  • I C Zampini, J Villena, S Salva, M Herrera, M I Isla, S Alvarez. Potentiality of standardized extract and isolated flavonoids from Zuccagnia punctata for the treatment of respiratory infections by Streptococcus pneumoniae: in vitro and in vivo studies. Journal of ethnopharmacology. 2012 Mar; 140(2):287-92. doi: 10.1016/j.jep.2012.01.019. [PMID: 22285202]
  • Sang Hee Shim. 20S proteasome inhibitory activity of flavonoids isolated from Spatholobus suberectus. Phytotherapy research : PTR. 2011 Apr; 25(4):615-8. doi: 10.1002/ptr.3342. [PMID: 21104764]
  • Faustino E Morán Vieyra, Héctor J Boggetti, Iris C Zampini, Roxana M Ordoñez, María I Isla, Rosa M S Alvarez, Veridiana De Rosso, Adriana Z Mercadante, Claudio D Borsarelli. Singlet oxygen quenching and radical scavenging capacities of structurally-related flavonoids present in Zuccagnia punctata Cav. Free radical research. 2009 Jun; 43(6):553-64. doi: 10.1080/10715760902912264. [PMID: 19431060]
  • Juan Chen, Xue-Mei Ma, Yan-Ping Shi. Determination of seven flavonoids in Ixeridium gracile (DC.) Shih by high-performance liquid chromatography. Journal of AOAC International. 2009 May; 92(3):773-8. doi: . [PMID: 19610366]
  • Shu-ying Yao, Yun-bao Ma, Ya Tang, Ji-jun Chen, Xue-mei Zhang. [Chemical constituents of Oxytropis falcate]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Jun; 33(12):1418-21. doi: . [PMID: 18837346]
  • Yu Zhang, Juan Chen, Xue-Mei Ma, Yan-Ping Shi. Simultaneous determination of flavonoids in Ixeridium gracile by micellar electrokinetic chromatography. Journal of pharmaceutical and biomedical analysis. 2007 Dec; 45(5):742-6. doi: 10.1016/j.jpba.2007.08.014. [PMID: 17889478]
  • Laura Svetaz, Alejandro Tapia, Silvia N López, Ricardo L E Furlán, Elisa Petenatti, Rosanna Pioli, Guillermo Schmeda-Hirschmann, Susana A Zacchino. Antifungal chalcones and new caffeic acid esters from Zuccagnia punctata acting against soybean infecting fungi. Journal of agricultural and food chemistry. 2004 Jun; 52(11):3297-300. doi: 10.1021/jf035213x. [PMID: 15161186]
  • Osamu Shirota, Vibha Pathak, Setsuko Sekita, Motoyoshi Satake, Yoshio Nagashima, Yutaka Hirayama, Yusuke Hakamata, Tatsuo Hayashi. Phenolic constituents from Dalbergia cochinchinensis. Journal of natural products. 2003 Aug; 66(8):1128-31. doi: 10.1021/np0300683. [PMID: 12932142]