senegalensin (BioDeep_00000000667)
Secondary id: BioDeep_00000269652, BioDeep_00000400489
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C25H28O5 (408.1937)
中文名称: 6,8-二异戊二烯基柚皮素
谱图信息:
最多检出来源 Viridiplantae(plant) 76.56%
分子结构信息
SMILES: C1(O)C(C/C=C(/C)\C)=C2O[C@]([H])(C3C=CC(O)=CC=3)CC(=O)C2=C(O)C=1C/C=C(\C)/C
InChI: InChI=1S/C25H28O5/c1-14(2)5-11-18-23(28)19(12-6-15(3)4)25-22(24(18)29)20(27)13-21(30-25)16-7-9-17(26)10-8-16/h5-10,21,26,28-29H,11-13H2,1-4H3/t21-/m0/s1
描述信息
6,8-diprenylnaringenin is a trihydroxyflavanone that is (S)-naringenin substituted by prenyl groups at positions 6 and 8. It has a role as a plant metabolite and an antibacterial agent. It is a trihydroxyflavanone, a member of 4-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin.
Lonchocarpol A is a natural product found in Macaranga conifera, Erythrina suberosa, and other organisms with data available.
A trihydroxyflavanone that is (S)-naringenin substituted by prenyl groups at positions 6 and 8.
同义名列表
13 个代谢物同义名
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methyl-2-butenyl)-, (S)-; (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-1-benzopyran-4-one; 5,4-dihydroxy-8-(gamma,gamma-dimethylallyl)-(5-(hydroxyisopropyl)dihydrofurano(2,3-6.7))isoflavone; (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one; (S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-en-1-yl)chroman-4-one; (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-enyl)chroman-4-one; 6,8-Diprenylnaringenin; Lonchocarpol A; Senegalensien; Senegalensein; senegalensin; MLS000876964; Lonchocarpol A
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:2156
- KEGG: C09724
- PubChem: 124035
- Metlin: METLIN52760
- ChEMBL: CHEMBL477969
- LipidMAPS: LMPK12140276
- MeSH: senegalensin
- ChemIDplus: 0068236113
- CAS: 68236-11-3
- medchemexpress: HY-122416
- PMhub: MS000010419
- MetaboLights: MTBLC2156
- PubChem: 11912
- KNApSAcK: C00000954
- 3DMET: B03223
- NIKKAJI: J607.242I
- LOTUS: LTS0012096
- wikidata: Q27105565
- KNApSAcK: 2156
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
17 个相关的物种来源信息
- 171251 - Citrus medica:
- 53865 - Derris laxiflora: 10.1080/10575639508043163
- 556509 - Erythrina fusca:
- 157649 - Erythrina senegalensis:
- 1977555 - Erythrina sigmoidea: 10.1055/S-2006-960179
- 1288013 - Erythrina suberosa: 10.1021/NP0101696
- 520843 - Flemingia macrophylla: 10.1055/S-2005-871297
- 74859 - Glycyrrhiza pallidiflora: 10.3987/COM-89-5304
- 3486 - Humulus lupulus:
- 159053 - Limonia acidissima: 10.1016/S0031-9422(01)00423-X
- 185976 - Lonchocarpus minimiflorus:
- 3873 - Lupinus luteus:
- 109817 - Macaranga conifera: 10.1016/S0031-9422(02)00378-3
- 210328 - Maclura tricuspidata: 10.1021/NP800418J
- 1485847 - Melipotis perpendicularis: 10.1021/NP9703961
- 1902362 - Monotes engleri: 10.1002/HLCA.19980810325
- 171567 - Sophora tetraptera: 10.1016/0031-9422(95)91511-X
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jongmin Ahn, Young-Mi Kim, Hee-Sung Chae, Young Hee Choi, Hee-Chul Ahn, Hunseung Yoo, Minseok Kang, Jinwoong Kim, Young-Won Chin. Prenylated Flavonoids from the Roots and Rhizomes of Sophora tonkinensis and Their Effects on the Expression of Inflammatory Mediators and Proprotein Convertase Subtilisin/Kexin Type 9.
Journal of natural products.
2019 02; 82(2):309-317. doi:
10.1021/acs.jnatprod.8b00748. [PMID: 30698432] - Pranorm Khaomek, Chikara Ichino, Aki Ishiyama, Hitomi Sekiguchi, Miyuki Namatame, Nijsiri Ruangrungsi, Ekarin Saifah, Hiroaki Kiyohara, Kazuhiko Otoguro, Satoshi Omura, Haruki Yamada. In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca.
Journal of natural medicines.
2008 Apr; 62(2):217-20. doi:
10.1007/s11418-007-0214-z. [PMID: 18404327] - Adiaratou Togola, Ingvild Austarheim, Annette Theïs, Drissa Diallo, Berit Smestad Paulsen. Ethnopharmacological uses of Erythrina senegalensis: a comparison of three areas in Mali, and a link between traditional knowledge and modern biological science.
Journal of ethnobiology and ethnomedicine.
2008 Mar; 4(?):6. doi:
10.1186/1746-4269-4-6. [PMID: 18321374] - Md Mukhlesur Rahman, Alexander I Gray. Antimicrobial constituents from the stem bark of Feronia limonia.
Phytochemistry.
2002 Jan; 59(1):73-7. doi:
10.1016/s0031-9422(01)00423-x. [PMID: 11754947] - N G Coldham, M J Sauer. Identification, quantitation and biological activity of phytoestrogens in a dietary supplement for breast enhancement.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2001 Dec; 39(12):1211-24. doi:
10.1016/s0278-6915(01)00081-3. [PMID: 11696395] - H Tanaka, M Doi, H Etoh, N Watanabe, H Shimizu, M Hirata, M Ahmad, I Qurashi, M R Khan. Revised structures for senegalensin and euchrenone b(10).
Journal of natural products.
2001 Oct; 64(10):1336-40. doi:
10.1021/np0101696. [PMID: 11678662] - M J Salvatore, A B King, A C Graham, H R Onishi, K F Bartizal, G K Abruzzo, C J Gill, H G Ramjit, S M Pitzenberger, K M Witherup. Antibacterial activity of lonchocarpol A.
Journal of natural products.
1998 May; 61(5):640-2. doi:
10.1021/np9703961. [PMID: 9599265] - J Wandji, A E Nkengfack, Z T Fomum, R Ubillas, K B Killday, M S Tempesta. A new prenylated isoflavone and long chain esters from two Erythrina species.
Journal of natural products.
1990 Nov; 53(6):1425-9. doi:
10.1021/np50072a004. [PMID: 2089116]
