Butrin (BioDeep_00000007497)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(S) -7- (beta-D-Glucopyranosyloxy) -2- [ 3- (beta-D-glucopyranosyloxy) -4-hydroxyphenyl ] -2,3-dihydro-4H-1-benzopyran-4-one

化学式: C27H32O15 (596.1741)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c(c1)c(O[C@@H]([C@@H](O)5)OC([C@H](O)[C@H](O)5)CO)cc(O2)c1C(C[C@@](c(c3)ccc(O)c(O[C@H](O4)[C@@H](O)[C@H]([C@@H](O)C(CO)4)O)3)2[H])=O
InChI: InChI=1S/C27H32O15/c28-8-18-20(32)22(34)24(36)26(41-18)38-11-2-3-12-14(31)7-15(39-16(12)6-11)10-1-4-13(30)17(5-10)40-27-25(37)23(35)21(33)19(9-29)42-27/h1-6,15,18-30,32-37H,7-9H2/t15-,18+,19+,20+,21+,22-,23-,24+,25+,26+,27+/m0/s1

描述信息

A flavanone glycoside that is butin substituted by two beta-D-glucopyranosyl residues at positions 7 and 3 respectively.

同义名列表

3 个代谢物同义名

Butrin; (S) -7- (beta-D-Glucopyranosyloxy) -2- [ 3- (beta-D-glucopyranosyloxy) -4-hydroxyphenyl ] -2,3-dihydro-4H-1-benzopyran-4-one; Butrin



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 CAT, CCND1, CTNNB1, HPGDS, NFKB1, NFKBIA, ODC1, SIRT1
Peripheral membrane protein 1 GORASP1
Nucleus 5 CCND1, CTNNB1, NFKB1, NFKBIA, SIRT1
cytosol 8 CAT, CCND1, CTNNB1, HPGDS, NFKB1, NFKBIA, ODC1, SIRT1
centrosome 2 CCND1, CTNNB1
nucleoplasm 6 CCND1, CTNNB1, HPGDS, NFKB1, NFKBIA, SIRT1
Cell membrane 4 CTNNB1, SCN10A, SCN9A, TNF
Cytoplasmic side 1 GORASP1
lamellipodium 1 CTNNB1
Cell projection, axon 1 SCN9A
Multi-pass membrane protein 2 SCN10A, SCN9A
Golgi apparatus membrane 1 GORASP1
Synapse 1 CTNNB1
cell cortex 1 CTNNB1
cell junction 1 CTNNB1
cell surface 1 TNF
glutamatergic synapse 2 CTNNB1, SCN10A
Golgi apparatus 1 GORASP1
Golgi membrane 1 GORASP1
neuronal cell body 1 TNF
presynaptic membrane 2 CTNNB1, SCN10A
plasma membrane 5 CTNNB1, NFKBIA, SCN10A, SCN9A, TNF
Membrane 3 CAT, CTNNB1, SCN9A
axon 2 SCN10A, SCN9A
basolateral plasma membrane 1 CTNNB1
extracellular exosome 3 CAT, CTNNB1, SCN10A
extracellular space 2 CXCL8, TNF
perinuclear region of cytoplasm 1 CTNNB1
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 2 CCND1, CTNNB1
mitochondrion 3 CAT, NFKB1, SIRT1
protein-containing complex 2 CAT, CTNNB1
intracellular membrane-bounded organelle 2 CAT, HPGDS
chromatin silencing complex 1 SIRT1
Secreted 1 CXCL8
extracellular region 4 CAT, CXCL8, NFKB1, TNF
mitochondrial matrix 1 CAT
transcription regulator complex 2 CTNNB1, NFKB1
Nucleus membrane 1 CCND1
nuclear membrane 1 CCND1
external side of plasma membrane 1 TNF
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
nucleolus 1 SIRT1
Wnt signalosome 1 CTNNB1
apical part of cell 1 CTNNB1
cell-cell junction 1 CTNNB1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 CTNNB1
heterochromatin 1 SIRT1
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 CTNNB1
focal adhesion 2 CAT, CTNNB1
cis-Golgi network 1 GORASP1
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 SIRT1
PML body 1 SIRT1
fascia adherens 1 CTNNB1
lateral plasma membrane 1 CTNNB1
nuclear inner membrane 1 SIRT1
Cell projection, neuron projection 1 SCN9A
chromatin 2 NFKB1, SIRT1
phagocytic cup 1 TNF
cell periphery 1 CTNNB1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
spindle pole 1 CTNNB1
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
fibrillar center 1 SIRT1
nuclear envelope 1 SIRT1
Endomembrane system 1 CTNNB1
euchromatin 2 CTNNB1, SIRT1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, NFKB1
transcription repressor complex 1 CCND1
axon terminus 1 SCN9A
specific granule lumen 1 NFKB1
node of Ranvier 1 SCN9A
beta-catenin-TCF complex 1 CTNNB1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
presynaptic active zone cytoplasmic component 1 CTNNB1
protein-DNA complex 1 CTNNB1
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
catenin complex 1 CTNNB1
voltage-gated sodium channel complex 2 SCN10A, SCN9A
cyclin-dependent protein kinase holoenzyme complex 1 CCND1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
clathrin complex 1 SCN10A
cyclin D1-CDK4 complex 1 CCND1
beta-catenin-TCF7L2 complex 1 CTNNB1
[Nuclear factor NF-kappa-B p105 subunit]: Cytoplasm 1 NFKB1
[Nuclear factor NF-kappa-B p50 subunit]: Nucleus 1 NFKB1
I-kappaB/NF-kappaB complex 2 NFKB1, NFKBIA
NF-kappaB p50/p65 complex 1 NFKB1
cyclin D1-CDK6 complex 1 CCND1
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1


文献列表

  • Isabelle Krolikiewicz-Renimel, Thomas Michel, Emilie Destandau, Madhukar Reddy, Patrice André, Claire Elfakir, Chantal Pichon. Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities. Journal of ethnopharmacology. 2013 Jul; 148(2):537-43. doi: 10.1016/j.jep.2013.05.001. [PMID: 23680157]
  • Anuradha Sehrawat, Vijay Kumar. Butein imparts free radical scavenging, anti-oxidative and proapoptotic properties in the flower extracts of Butea monosperma. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. 2012 Aug; 36(2):63-71. doi: . [PMID: 23185781]
  • Zafar Rasheed, Nahid Akhtar, Abubakar Khan, Khursheed A Khan, Tariq M Haqqi. Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8. The Journal of pharmacology and experimental therapeutics. 2010 May; 333(2):354-63. doi: 10.1124/jpet.109.165209. [PMID: 20164300]
  • A Sehrawat, T H Khan, L Prasad, S Sultana. Butea monosperma and chemomodulation: protective role against thioacetamide-mediated hepatic alterations in Wistar rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2006 Feb; 13(3):157-63. doi: 10.1016/j.phymed.2004.11.007. [PMID: 16428022]