Chemical Formula: C15H12O2

Chemical Formula C15H12O2

Found 64 metabolite its formula value is C15H12O2

Flavanone

2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one

C15H12O2 (224.0837252)


Flavonoids (or bioflavonoids) (from the Latin word flavus meaning yellow), also collectively known as Vitamin P and citrin, are a class of plant secondary metabolites or yellow pigments having a structure similar to that of flavones. Flavonoids is found in many foods, some of which are blackcurrant, wild celery, rose hip, and turmeric. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1]. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1].

   

2-Hydroxychalcone

2-Propen-1-one,1-(2-hydroxyphenyl)-3-phenyl-, (2E)-

C15H12O2 (224.0837252)


   

4-Hydroxychalcone

1-(4-hydroxyphenyl)-3-phenylprop-2-en-1-one

C15H12O2 (224.0837252)


4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria[1][2][3].

   

Isoflavanone

2,3-dihydro-3-Phenyl-4H-1-benzopyran-4-one

C15H12O2 (224.0837252)


   

4-Hydroxychalcone

(2Z)-3-(4-hydroxyphenyl)-1-phenylprop-2-en-1-one

C15H12O2 (224.0837252)


4-Hydroxychalcone is found in herbs and spices. 4-Hydroxychalcone is a constituent of Glycyrrhiza glabra (licorice) roots 4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity[1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice[2].

   

1-Methoxy-2-hydroxyanthracene

1-Methoxy-2-hydroxyanthracene

C15H12O2 (224.0837252)


   

Flavanone

(2S)-Flavanone

C15H12O2 (224.0837252)


Annotation level-1 Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1]. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1].

   
   

Flavanone

Propafenone Hydrochloride Imp. H (EP); Propafenone Imp. H (EP); (2RS)-2-Phenyl-2,3-dihydro-4H-1-benzopyran-4-one; Propafenone Hydrochloride Impurity H; Propafenone Impurity H

C15H12O2 (224.0837252)


Flavanone is the simplest member of the class of flavanones that consists of flavan bearing an oxo substituent at position 4. It derives from a hydride of a flavan. Flavanone is a natural product found in Annona muricata, Ginkgo biloba, and other organisms with data available. The simplest member of the class of flavanones that consists of flavan bearing an oxo substituent at position 4. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1]. Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase)[1].

   

6-[(1Z,2Z)-3-Hydroxy-3-phenyl-2-propene-1-ylidene]-2,4-cyclohexadiene-1-one

6-[(1Z,2Z)-3-Hydroxy-3-phenyl-2-propene-1-ylidene]-2,4-cyclohexadiene-1-one

C15H12O2 (224.0837252)


   

9H-Fluoren-9-ylmethyl Formate

9H-Fluoren-9-ylmethyl formic acid

C15H12O2 (224.0837252)


   

2,3-Diphenylacrylic acid

2,3-diphenylprop-2-enoic acid

C15H12O2 (224.0837252)


   

Pterocarpan

8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2,4,6,11,13,15-hexaene

C15H12O2 (224.0837252)


   

Dibenzoylmethane

1,3-Diphenylpropane-1,3-dione

C15H12O2 (224.0837252)


Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2[1]. Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2[1].

   

Phenylbenzylglyoxal

1,3-diphenylpropane-1,2-dione

C15H12O2 (224.0837252)


   

Isoflavanone

Isoflavanone

C15H12O2 (224.0837252)


Isoflavone in which the double bond between positions 2 and 3 has been reduced to a single bond.

   

Dibenzoylmethane

Dibenzoylmethane 1,3-Diphenyl-1,3-propanedione

C15H12O2 (224.0837252)


Dibenzoylmethane is a beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects. It has a role as an antineoplastic agent, a metabolite and an antimutagen. It is a beta-diketone and an aromatic ketone. Dibenzoylmethane is a natural product found in Acca sellowiana with data available. A beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects. Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2[1]. Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2[1].

   
   

7-acetoxy-1-phenylhept-5E-ene-1,3-diyne|Ac-(E)-7-Phenyl-2-heptene-4,6-diyn-1-ol|Acetat des 1-Phenyl-hepten-(5)-trans-diin-(1.3)-ols-(7)|acetic acid-(7-phenyl-hept-2t-ene-4,6-diynyl ester)|Essigsaeure-(7-phenyl-hept-2t-en-4,6-diinylester)|trans-1-Phenyl-hepten-(5)-diin-(1,3)-yl-(7)-acetat

7-acetoxy-1-phenylhept-5E-ene-1,3-diyne|Ac-(E)-7-Phenyl-2-heptene-4,6-diyn-1-ol|Acetat des 1-Phenyl-hepten-(5)-trans-diin-(1.3)-ols-(7)|acetic acid-(7-phenyl-hept-2t-ene-4,6-diynyl ester)|Essigsaeure-(7-phenyl-hept-2t-en-4,6-diinylester)|trans-1-Phenyl-hepten-(5)-diin-(1,3)-yl-(7)-acetat

C15H12O2 (224.0837252)


   
   

1,3-diphenyl-1,2-propanedione

1,3-diphenyl-1,2-propanedione

C15H12O2 (224.0837252)


   

7-methyl-2,6-phenanthrenediol

7-methyl-2,6-phenanthrenediol

C15H12O2 (224.0837252)


   
   

cis,cis-Tridecatrien-(2,10,12)-triin-(4,6,8)-yl-acetat

cis,cis-Tridecatrien-(2,10,12)-triin-(4,6,8)-yl-acetat

C15H12O2 (224.0837252)


   

Di-Me ether-3,5,7,9,11-Tridecapentayne-1,2-diol

Di-Me ether-3,5,7,9,11-Tridecapentayne-1,2-diol

C15H12O2 (224.0837252)


   

4-vinylphenyl benzoate

4-vinylphenyl benzoate

C15H12O2 (224.0837252)


   

azuleno[6,5-b]furan-5-carboxaldehyde, 3,8-dimethyl-

azuleno[6,5-b]furan-5-carboxaldehyde, 3,8-dimethyl-

C15H12O2 (224.0837252)


   

3,5-Dimethyl-4-methylenenaphtho[2,3-b]furan-9(4H)-one

3,5-Dimethyl-4-methylenenaphtho[2,3-b]furan-9(4H)-one

C15H12O2 (224.0837252)


   

Chalcone, 3

2-Propen-1-one, 3-(4-hydroxyphenyl)-1-phenyl-, (2E)-

C15H12O2 (224.0837252)


4-hydroxychalcone is a member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4. It has a role as a plant metabolite and an antihypertensive agent. It is a member of chalcones and a member of phenols. It is functionally related to a trans-chalcone. A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4. 4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity[1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice[2].

   

Spectrum5_000333

2-Propen-1-one, 1-(4-hydroxyphenyl)-3-phenyl-, (2E)-

C15H12O2 (224.0837252)


4-hydroxychalcone is a member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4. It has a role as an anti-inflammatory agent and an antineoplastic agent. It is a member of chalcones and a member of phenols. 4'-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria[1][2][3].

   

O-Hydroxychalcone

O-Hydroxychalcone

C15H12O2 (224.0837252)


   

2-Hydroxychalcone

2-Propen-1-one,1-(2-hydroxyphenyl)-3-phenyl-, (2E)-

C15H12O2 (224.0837252)


2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3]. 2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3].

   

(4S,5Z,6S)-4-(2-methoxy-2-oxoethyl)-5-[2-[(E)-3-phenylprop-2-enoyl]oxyethylidene]-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylic acid

(4S,5Z,6S)-4-(2-methoxy-2-oxoethyl)-5-[2-[(E)-3-phenylprop-2-enoyl]oxyethylidene]-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylic acid

C15H12O2 (224.0837252)


   

4-Hydroxychalcone

4-Hydroxychalcone

C15H12O2 (224.0837252)


   

9-fluorenyl acetate

9-fluorenyl acetate

C15H12O2 (224.0837252)


   

2-(4-PHENYLPHENYL)MALONDIALDEHYDE

2-(4-PHENYLPHENYL)MALONDIALDEHYDE

C15H12O2 (224.0837252)


   

(Z)-alpha-Phenylcinnamic acid

Benzeneacetic acid, a-(phenylmethylene)-, (aZ)-

C15H12O2 (224.0837252)


   

hydroxybenzalaceto-phenone

hydroxybenzalaceto-phenone

C15H12O2 (224.0837252)


   

3-benzylphthalide

3-benzylphthalide

C15H12O2 (224.0837252)


   

9-Fluoreneacetic acid

9-Fluorene acetic acid

C15H12O2 (224.0837252)


   

3-Acetylbenzophenone

3-Acetylbenzophenone

C15H12O2 (224.0837252)


   

4-phenylcinnamic acid

4-phenylcinnamic acid

C15H12O2 (224.0837252)


   

phenyl-(3-phenyloxiran-2-yl)methanone

phenyl-(3-phenyloxiran-2-yl)methanone

C15H12O2 (224.0837252)


   

2-HYDROXY-10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-ONE

2-HYDROXY-10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-ONE

C15H12O2 (224.0837252)


   

3,3-Diphenyl-2-propenoic acid

3,3-Diphenyl-2-propenoic acid

C15H12O2 (224.0837252)


   

1,3-diphenyl-2,3-epoxy-1-propanone

1,3-diphenyl-2,3-epoxy-1-propanone

C15H12O2 (224.0837252)


   

5-METHOXY-3-PHENYLBENZOFURAN

5-METHOXY-3-PHENYLBENZOFURAN

C15H12O2 (224.0837252)


   

3-([1,1-BIPHENYL]-3-YL)ACRYLIC ACID

3-([1,1-BIPHENYL]-3-YL)ACRYLIC ACID

C15H12O2 (224.0837252)


   

methyl 9H-fluorene-9-carboxylate

9H-Fluorene-9-carboxylicacid, methyl ester

C15H12O2 (224.0837252)


   

3-Acetyl-biphenyl-3-carbaldehyde

3-Acetyl-biphenyl-3-carbaldehyde

C15H12O2 (224.0837252)


   

4-(4-acetylphenyl)benzaldehyde

4-(4-acetylphenyl)benzaldehyde

C15H12O2 (224.0837252)


   

alpha-Phenylcinnamic acid

Benzeneacetic acid, a-(phenylmethylene)-

C15H12O2 (224.0837252)


   

6-(Benzyloxy)-1-benzofuran

6-(Benzyloxy)-1-benzofuran

C15H12O2 (224.0837252)


   

Phenylbenzylglyoxal

Phenylbenzylglyoxal

C15H12O2 (224.0837252)


   

(2R)-flavanone

(2R)-flavanone

C15H12O2 (224.0837252)


The (R)-enantiomer of flavanone.

   

Karenzu DK2

1,3-di(phenyl)propane-1,3-dione

C15H12O2 (224.0837252)


Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2[1]. Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. Dibenzoylmethane, an analog of curcumin, results in dissociation from Keap1 and nuclear translocation of Nrf2[1].

   

AI3-00855

2-Propen-1-one,3-(2-hydroxyphenyl)-1-phenyl-, (2E)-

C15H12O2 (224.0837252)


2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3]. 2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB[1][2][3].

   

CHEBI:36105

(2R)-2-phenyl-2,3-dihydro-4H-chromen-4-one

C15H12O2 (224.0837252)


   

CHEBI:15606

(2S)-2-phenyl-2,3-dihydro-4H-chromen-4-one

C15H12O2 (224.0837252)


   

(6aS,11aS)-pterocarpan

(6aS,11aS)-pterocarpan

C15H12O2 (224.0837252)


   

(6aR,11aR)-pterocarpan

(6aR,11aR)-pterocarpan

C15H12O2 (224.0837252)


   

(3S)-isoflavanone

(3S)-isoflavanone

C15H12O2 (224.0837252)


   

FLAVANONE (3,3-D2)

FLAVANONE (3,3-D2)

C15H12O2 (224.0837252)


   

(2S)-Flavanone

(2S)-Flavanone

C15H12O2 (224.0837252)


The (S)-enantiomer of flavanone.