D-Phenylalanine (BioDeep_00000014860)

Main id: BioDeep_00000000351

Secondary id: BioDeep_00001868210

human metabolite blood metabolite natural product


代谢物信息卡片


alpha-Amino-beta-phenylpropionic acid

  化学式: C9H11NO2 (165.079)
中文名称: DL-苯丙氨酸, L-苯丙氨酸
  谱图信息: 最多检出来源 Homo sapiens(blood) 23.56%

Reviewed

Last reviewed on 2024-07-29.

Cite this Page

D-Phenylalanine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/d-phenylalanine (retrieved 2025-07-27) (BioDeep RN: BioDeep_00000014860). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC=C(C=C1)CC(C(=O)O)N
InChI: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)

描述信息

Flavouring ingredient. (±)-Phenylalanine is found in many foods, some of which are cucumber, green bell pepper, yellow bell pepper, and saskatoon berry.

同义名列表

107 个代谢物同义名

alpha-Amino-beta-phenylpropionic acid; alpha-Amino-beta-phenylpropionate; a-Amino-b-phenylpropionic acid; 2-amino-3-phenylpropanoic acid; Α-amino-β-phenylpropionic acid; Α-amino-β-phenylpropionate; a-Amino-b-phenylpropionate; l-phenylalanine (2-13c); Phenylalanine, L-Isomer; Phenylalanine, L Isomer; L-Isomer Phenylalanine; (±)-Phenylalanine; DL-Phenylalanine; D-phenylalanine; L-Phenylalanine; Phenylalanine; phenylalanin; fenilalanina; Endorphenyl; phe; F; Phenylalanine; .alpha.-Amino-.beta.-phenylpropionic acid; .alpha.-Aminohydrocinnamic acid; .beta.-Phenyl-.alpha.-alanine; .beta.-Phenyl-.alpha.-alanine, l-; .beta.-Phenyl-L-alanine; .beta.-Phenylalanine; .beta.-Phenylalanine, dl-; (-)-.beta.-Phenylalanine; (.+-.)-Phenylalanine; (.+/-.)-Phenylalanine; (+/-)-.BETA.-PHENYL-.ALPHA.-ALANINE; (+/-)-2-Amino-3-phenylpropionic acid; (+/-)-3-PHENYL-2-AMINOPROPANOIC ACID; (+/-)-BETA-PHENYL-ALPHA-ALANINE; (+/-)-phenylalanine; (+/)2Amino3phenylpropionic acid; (2S)-2-amino-3-phenyl-propanoic acid; (DL)-PHENYLALANINE; (RS)-phenylalanine; 1,2-dilauroylphosphatidic acid; 1,2-dilauroylphosphatidic acid, sodium salt; 2-amino 3-phenylpropionic acid; 2-Amino-3-phenyl-propionic acid; 2-Amino-3-phenylpropionic acid; 2-Amino-3-phenylpropionic acid, dl-; 2-azaniumyl-3-phenylpropanoate; 2Amino3phenylpropionic acid, dl; 3-Phenyl-L-alanine; L-2-Amino-3-phenylpropionic acid; L-beta-Phenylalanine; 8P946UF12S; AI3-18436; Alanine, phenyl-; Alanine, phenyl-, dl-; Alanine, phenyl, DL; Alanine, phenyl, DL (8CI); alpha-Aminohydrocinnamic acid, dl-; alphaAminohydrocinnamic acid, dl; Butane,4-dichloro-1,4-diphenyl; C6H5CH2CH(NH2)COOH; D-.beta.-Phenylalanine; D-alpha-Aminohydrocinnamic acid; D-alpha-Amino-beta-phenylpropionic acid; D-beta-Phenyl-alpha-aminopropionic acid; D-PHE; d,1-phenylalanine; D,L-PHE; d,l-phenylalanine; DL-.alpha.-Amino-.beta.-phenylpropionic acid; DL-.beta.-Phenyl-.alpha.-alanine; DL-.beta.-Phenylalanine; DL-2-Amino-3-phenylpropanoic acid; DL-2-AMINO-3-PHENYLPROPIONIC ACID; DL-3-Phenylalanine; DL-alpha-Amino-beta-phenylpropionic acid; DL-Phe-OH;(+/-)-2-Amino-3-phenylpropionic acid; DL-phenyl alanine; DL-PHENYL(ALANINE-3-13C); DL-PHENYLALANINE [FCC]; DL-PHENYLALANINE [FHFI]; DL-PHENYLALANINE [WHO-DD]; DL-PHENYLALANINE-CARBOXY-13C; DL-Phenylalanine, 99%, FCC; DL-Phenylalanine, puriss., >=99.0% (NT); DL-Phenylalanine, ReagentPlus(R), 99%; DL-Phenylalanine, Vetec(TM) reagent grade, 98%; DL2Amino3phenylpropanoic acid; DL3Phenylalanine; DLalphaAminobetaphenylpropionic acid; DLPA; H-DL-Phe-OH; Hydrocinnamic acid, .alpha.-amino-; L-.beta.-Phenylalanine; L-Phenylalanine-d8; L-Phenylalanine, FCC, From Non Animal Source; L-Phenylalanine, non animal origin; NCI60_042233; NCIOpen2_000782; Phenyl-.alpha.-alanine; PHENYLALANINE DL; Phenylalanine DL-form; PHENYLALANINE DL-FORM [MI]; Phenylalanine DLform; Phenylalanine, dl; Phenylalanine, dl-; PHENYLALANINE,CLINICAL DETECTION,GENERAL BACTERIA TINY BIOCHEMICAL IDENTIFICATION TUBE; PHENYLALANINE,DL-; Tox21_110011; UNII-8P946UF12S; WLN: QVYZ1R -L



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

328 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 DAO, EEF2K, MME, PTGS1, PTGS2, SLC52A3, SRC, STAM2, TNK1
Peripheral membrane protein 5 DAO, PTGS1, PTGS2, STAM2, TNK1
Endoplasmic reticulum membrane 3 HSP90B1, PTGS1, PTGS2
Nucleus 3 HSP90B1, SLC52A3, SRC
cytosol 9 DAO, EEF2K, HSP90B1, LIPE, MFN2, PGM3, SRC, STAM2, UAP1
dendrite 1 MME
trans-Golgi network 1 MME
nucleoplasm 3 SRC, STAM2, UAP1
Cell membrane 7 DAO, DPP4, LIPE, MME, SLC3A1, SLC52A3, SRC
Lipid-anchor 1 SRC
Cytoplasmic side 1 STAM2
lamellipodium 1 DPP4
ruffle membrane 1 SRC
Early endosome membrane 1 STAM2
Multi-pass membrane protein 2 MFN2, SLC52A3
Synapse 1 MME
cell junction 2 DPP4, SRC
cell surface 2 DPP4, MME
glutamatergic synapse 2 EEF2K, SRC
Golgi apparatus 1 PTGS1
Golgi membrane 1 INS
lysosomal membrane 1 DPP4
mitochondrial inner membrane 1 SRC
neuronal cell body 2 MME, SRC
smooth endoplasmic reticulum 1 HSP90B1
synaptic vesicle 1 MME
Cytoplasm, cytosol 3 DAO, LIPE, UAP1
Lysosome 1 SRC
Presynapse 1 MME
plasma membrane 8 DAO, DPP4, MME, SLC3A1, SLC52A3, SRC, TNK1, UAP1
presynaptic active zone 1 DAO
Membrane 6 DPP4, HSP90B1, LIPE, MME, SLC3A1, TNK1
apical plasma membrane 3 DPP4, SLC3A1, SLC52A3
axon 1 MME
brush border 1 MME
caveola 3 LIPE, PTGS2, SRC
extracellular exosome 8 DAO, DPP4, HSP90B1, MME, PTGS1, SERPING1, SLC3A1, SRC
endoplasmic reticulum 2 HSP90B1, PTGS2
extracellular space 4 C1S, DAO, INS, SERPING1
perinuclear region of cytoplasm 2 HSP90B1, SRC
bicellular tight junction 1 DAO
intercellular canaliculus 1 DPP4
mitochondrion 2 MFN2, SRC
protein-containing complex 2 HSP90B1, PTGS2
intracellular membrane-bounded organelle 2 PTGS1, STAM2
Microsome membrane 2 PTGS1, PTGS2
postsynaptic density 1 EEF2K
Secreted 3 DAO, DPP4, INS
extracellular region 6 C1S, DAO, DPP4, HSP90B1, INS, SERPING1
Mitochondrion outer membrane 1 MFN2
Single-pass membrane protein 1 DPP4
mitochondrial outer membrane 1 MFN2
Extracellular side 1 DAO
anchoring junction 1 DPP4
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 SLC52A3
nuclear membrane 1 SLC52A3
dendritic spine 1 EEF2K
cytoplasmic vesicle 1 MME
microtubule cytoskeleton 1 MFN2
midbody 1 HSP90B1
Early endosome 1 MME
Single-pass type II membrane protein 3 DPP4, MME, SLC3A1
Apical cell membrane 3 DPP4, SLC3A1, SLC52A3
Cytoplasm, perinuclear region 1 SRC
Mitochondrion inner membrane 1 SRC
Membrane raft 3 DPP4, MME, SRC
Cell junction, focal adhesion 1 SRC
Cytoplasm, cytoskeleton 1 SRC
focal adhesion 4 DPP4, HSP90B1, MME, SRC
Peroxisome 1 DAO
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
collagen-containing extracellular matrix 2 HSP90B1, SERPING1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 SRC
neuron projection 2 PTGS1, PTGS2
cell projection 1 DAO
podosome 1 SRC
Secreted, extracellular space 1 DAO
brush border membrane 1 SLC3A1
actin filament 1 SRC
blood microparticle 2 C1S, SERPING1
Endomembrane system 2 DPP4, PTGS1
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Melanosome 1 HSP90B1
dendritic growth cone 1 SRC
sperm plasma membrane 1 HSP90B1
synaptic membrane 1 SRC
secretory granule lumen 1 INS
secretory granule membrane 1 MME
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 HSP90B1, INS, PTGS2, SERPING1
platelet alpha granule lumen 1 SERPING1
specific granule lumen 1 DAO
endocytic vesicle 2 DPP4, STAM2
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
[Isoform 2]: Cytoplasm 1 SLC52A3
Sarcoplasmic reticulum lumen 1 HSP90B1
ESCRT-0 complex 1 STAM2
[Isoform 1]: Cell membrane 1 SLC52A3
postsynaptic specialization, intracellular component 1 SRC
lamellipodium membrane 1 DPP4
endocytic vesicle lumen 1 HSP90B1
Cell projection, lamellipodium membrane 1 DPP4
Cell projection, invadopodium membrane 1 DPP4
vacuolar membrane 1 SLC3A1
endoplasmic reticulum chaperone complex 1 HSP90B1
neuron projection terminus 1 MME
dendritic filopodium 1 SRC
[Dipeptidyl peptidase 4 soluble form]: Secreted 1 DPP4


文献列表

  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Niels Laschinsky, Karin Kottwitz, Barbara Freund, Bernd Dresow, Roland Fischer, Peter Nielsen. Bioavailability of chromium(III)-supplements in rats and humans. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2012 Oct; 25(5):1051-60. doi: 10.1007/s10534-012-9571-5. [PMID: 22814636]
  • Kyung Hyun Min, Hong Jae Lee, Kwangmeyung Kim, Ick Chan Kwon, Seo Young Jeong, Sang Cheon Lee. The tumor accumulation and therapeutic efficacy of doxorubicin carried in calcium phosphate-reinforced polymer nanoparticles. Biomaterials. 2012 Aug; 33(23):5788-97. doi: 10.1016/j.biomaterials.2012.04.057. [PMID: 22591612]
  • Ahn Na Koo, Kyung Hyun Min, Hong Jae Lee, Sang-Uk Lee, Kwangmeyung Kim, Ick Chan Kwon, Sun Hang Cho, Seo Young Jeong, Sang Cheon Lee. Tumor accumulation and antitumor efficacy of docetaxel-loaded core-shell-corona micelles with shell-specific redox-responsive cross-links. Biomaterials. 2012 Feb; 33(5):1489-99. doi: 10.1016/j.biomaterials.2011.11.013. [PMID: 22130564]
  • Abd El-Moneim M R Afify, Hossam S El-Beltagi, Samiha M Abd El-Salam, Azza A Omran. Protein solubility, digestibility and fractionation after germination of sorghum varieties. PloS one. 2012; 7(2):e31154. doi: 10.1371/journal.pone.0031154. [PMID: 22319611]
  • Shoucheng Pu, Yuanqiang Guo, Wenyuan Gao. [Chemical constituents from Centipeda minima]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2009 Jun; 34(12):1520-2. doi: . [PMID: 19777837]
  • Adrian Mondry. Antiglucocorticoid RU38486 reduces net protein catabolism in experimental acute renal failure. BMC nephrology. 2005 Feb; 6(?):2. doi: 10.1186/1471-2369-6-2. [PMID: 15715918]
  • B Maggio. Modulation of phospholipase A2 by electrostatic fields and dipole potential of glycosphingolipids in monolayers. Journal of lipid research. 1999 May; 40(5):930-9. doi: 10.1016/s0022-2275(20)32128-3. [PMID: 10224162]
  • T Uchiumi, R R Traut, K Elkon, R Kominami. A human autoantibody specific for a unique conserved region of 28 S ribosomal RNA inhibits the interaction of elongation factors 1 alpha and 2 with ribosomes. The Journal of biological chemistry. 1991 Feb; 266(4):2054-62. doi: NULL. [PMID: 1989969]
  • K Fukushima, Y Muraoka, T Inoue, R Shimozawa. Conformational study of poly(L-lysine) interacting with acidic phospholipid vesicles. Biophysical chemistry. 1989 Sep; 34(1):83-90. doi: 10.1016/0301-4622(89)80045-6. [PMID: 2611343]
  • T Inoue, T Iwanaga, K Fukushima, R Shimozawa, Y Suezaki. Interaction of surfactants with bilayer of negatively charged lipid: effect on gel-to-liquid-crystalline phase transition of dilauroylphosphatidic acid vesicle membrane. Chemistry and physics of lipids. 1988 Oct; 48(3-4):189-96. doi: 10.1016/0009-3084(88)90089-8. [PMID: 3242947]


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