LeachianoneG (BioDeep_00000000918)
Secondary id: BioDeep_00001867564
human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C20H20O6 (356.126)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 20%
分子结构信息
SMILES: C1(O)C(C/C=C(\C)/C)=C2O[C@H](C3C=CC(O)=CC=3O)CC(=O)C2=C(O)C=1
InChI: InChI=1S/C20H20O6/c1-10(2)3-5-13-15(23)8-16(24)19-17(25)9-18(26-20(13)19)12-6-4-11(21)7-14(12)22/h3-4,6-8,18,21-24H,5,9H2,1-2H3/t18-/m0/s1
描述信息
Leachianone G is a tetrahydroxyflavanone having the hydroxy groups at the 2-, 4-, 5- and 7-positions and a prenyl group at 8-position. It is a tetrahydroxyflavanone, a member of 4-hydroxyflavanones and a (2S)-flavan-4-one. It is functionally related to a (S)-naringenin. It is a conjugate acid of a leachianone G(1-).
Leachianone G is a natural product found in Morus alba, Sophora flavescens, and Lespedeza cyrtobotrya with data available.
同义名列表
11 个代谢物同义名
Leachianone GLeucopelargonidin3-Deoxy-4-O-methylsappanolEpimedokoreanin BQingyangshengenin11-Deoxymogroside IIIE3-O-Acetyloleanolic acidLupulone CMbamiloside Ap-Hydroxyphenethyl trans-ferulate2-Hydroxyl emodin-1-methyl ether; 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-8-(3-methyl-2-butenyl)-, (2S)-; (2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one; (2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one; (-)-(2S)-5,7-dihydroxy-8-(2-hydroxy-3-methylbut-2-enyl)-2-(4-hydroxyphenyl)chroman-4-one; (2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-enyl)chroman-4-one; (-)-(2S)-2-hydroxy-8-dimethylallylnaringenin; 5,7,2,4-Tetrahydroxy-8-prenylflavanone; (+/-)-Leachianone G; Leachianone G; LeachianoneG
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:50208
- KEGG: C18024
- PubChem: 11810419
- PubChem: 5275227
- HMDB: HMDB0137502
- Metlin: METLIN52972
- ChEMBL: CHEMBL516930
- LipidMAPS: LMPK12140490
- MeSH: leachianone G
- MetaCyc: CPD-9442
- CAS: 152464-78-3
- medchemexpress: HY-N3395HY-N11412HY-N9316HY-N3831HY-N1375HY-N6991HY-N2618HY-N9969HY-N11164HY-N3078HY-N9961
- PMhub: MS000026296
- PubChem: 96024244
- KNApSAcK: C00014164
- NIKKAJI: J862.623E
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
6 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 701533 - Lespedeza cyrtobotrya: 10.1021/NP800395J
- 701533 - Lespedeza cyrtobotrya: 10.1021/NP800535G
- 3498 - Morus alba: 10.1016/S0031-9422(02)00753-7
- 49840 - Sophora flavescens:
- 49840 - Sophora flavescens: 10.1021/NP50102A033
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kaitlin Deardorff, William Ray, Eric Winterstein, MacKenzie Brown, Jocelyn McCornack, Brianda Cardenas-Garcia, Kiah Jones, Sarah McNutt, Shannon Fulkerson, Daneel Ferreira, Charlotte Gény, Xiaoyan Chen, Gil Belofsky, Blaise Dondji. Phenolic Metabolites of Dalea ornata Affect Both Survival and Motility of the Human Pathogenic Hookworm Ancylostoma ceylanicum.
Journal of natural products.
2016 09; 79(9):2296-303. doi:
10.1021/acs.jnatprod.6b00444. [PMID: 27584977] - Maya Mori-Hongo, Hiromi Yamaguchi, Tsutomu Warashina, Toshio Miyase. Melanin synthesis inhibitors from Lespedeza cyrtobotrya.
Journal of natural products.
2009 Jan; 72(1):63-71. doi:
10.1021/np800535g. [PMID: 19102656] - Ping Zhao, Kenichiro Inoue, Isao Kouno, Hirobumi Yamamoto. Characterization of leachianone G 2"-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures.
Plant physiology.
2003 Nov; 133(3):1306-13. doi:
10.1104/pp.103.025213. [PMID: 14551337] - Jiang Du, Zhen-Dan He, Ren-Wang Jiang, Wen-Cai Ye, Hong-Xi Xu, Paul Pui-Hay But. Antiviral flavonoids from the root bark of Morus alba L.
Phytochemistry.
2003 Apr; 62(8):1235-8. doi:
10.1016/s0031-9422(02)00753-7. [PMID: 12648543] - Ping Zhao, Chie Hamada, Kenichiro Inoue, Hirobumi Yamamoto. Efficient production and capture of 8-prenylnaringenin and leachianone G-biosynthetic intermediates of sophoraflavanone G--by the addition of cork tissue to cell suspension cultures of Sophora flavescens.
Phytochemistry.
2003 Apr; 62(7):1093-9. doi:
10.1016/s0031-9422(02)00671-4. [PMID: 12591262] - M Kuroyanagi, T Arakawa, Y Hirayama, T Hayashi. Antibacterial and antiandrogen flavonoids from Sophora flavescens.
Journal of natural products.
1999 Dec; 62(12):1595-9. doi:
10.1021/np990051d. [PMID: 10654410]
