Harmaline (BioDeep_00000000129)

 

Secondary id: BioDeep_00000276200

natural product human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-

化学式: C13H14N2O (214.1106)
中文名称: 骆驼蓬碱, 骆驼蓬灵
谱图信息: 最多检出来源 Viridiplantae(plant) 9.57%

分子结构信息

SMILES: CC1=C2C(=C3C=CC(=CC3=N2)OC)CCN1
InChI: InChI=1/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,14H,5-6H2,1-2H3

描述信息

Harmaline is a harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond. It has a role as a oneirogen. It derives from a hydride of a harman.
Harmaline is a natural product found in Passiflora pilosicorona, Passiflora boenderi, and other organisms with data available.
A beta-carboline alkaloid isolated from seeds of PEGANUM.
A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
Harmaline is found in fruits. Harmaline is an alkaloid from Passiflora incarnata (maypops
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
D004791 - Enzyme Inhibitors > D008996 - Monoamine Oxidase Inhibitors
Acquisition and generation of the data is financially supported in part by CREST/JST.
KEIO_ID H027; [MS2] KO008994
KEIO_ID H027

同义名列表

68 个代谢物同义名

3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-; 3H-Pyrido(3,4-b)indole, 4,9-dihydro-7-methoxy-1-methyl-; 7-METHOXY-1-METHYL-4,9-DIHYDRO-3H-PYRIDO(3,4-B)INDOLE; 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido(3,4-b)indole; 3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole; 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole; 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole; 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole; 3,4-Dihydro-7-methoxy-1-methyl-9H-pyrid[3,4-b]indole; 3,4-Dihydro-7-methoxy-1-methyl-9-pyrido(3,4-b)indole; 3,4-Dihydro-7-methoxy-1-methyl-9-pyrid(3,4-b)indole; 3,4-Dihydro-7-methoxy-1-methyl-9-pyrid[3,4-b]indole; 7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline #; 7-methoxy-1-methyl-3,4-dihydro-2h-beta-carboline; 7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline; 7-Methoxy-1-methyl-2,9-dihydro-1H-beta-carboline; 1-Methyl-7-methoxy-3,4-dihydro-.beta.-carboline; 7-methoxy-1-methyl-3H,4H,9H-pyrido[3,4-b]indole; 1-Methyl-7-methoxy-3, 4-dihydro-beta -carboline; 1-Methyl-7-methoxy-3,4-dihydro- beta-carboline; 1-Methyl-7-methoxy-3,4-dihydro-beta -carboline; 7-methoxy-1-methyl-4,9-dihydro-3H-b-carboline; 1-Methyl-7-methoxy-3,4-dihydro-beta-carboline; 3,4-Dihydro-7-methoxy-1-methyl-beta-carboline; 7-Methoxy-1-methyl-4,9-dihydro-3H-?-carboline; 7-Methoxy-1-methyl-4,9-dihydro-3H-β-carboline; 7-methoxy-1-methyl-3,4-dihydrobeta-carboline; 3H-Pyrido[3, 4,9-dihydro-7-methoxy-1-methyl-; 3,4-Dihydro-7-methoxy-1-methyl-b-carboline; Harmalol methyl ether; 3, 4-Dihydroharmine; 3,4-Dihydroharmine; Prestwick1_000610; Prestwick2_000610; Prestwick0_000610; Harmine, dihydro-; HARMALINE [MART.]; Prestwick3_000610; Spectrum5_001452; HARMALINE [HSDB]; O-Methylharmalol; Spectrum3_000720; Spectrum4_000824; Spectrum2_000411; UNII-CN58I4TOET; Dihydro-Harmine; Dihydroharmine; HARMALINE [MI]; BPBio1_000572; Oprea1_112644; MEGxp0_001874; DivK1c_000950; KBio1_000950; ACon1_000019; 3,4-b]indole; KBio2_005917; KBio2_003349; KBio2_000781; KBio3_001759; IDI1_000950; CN58I4TOET; Harmidine; Harmaline; A1-00783; harmalin; Armalin; HARMALINE HYDROCHLORIDE DIHYDRATE; Harmaline



数据库引用编号

47 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(1)

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

109 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 CA1, CASP3, CASP8, CAT, CNR1, CYP1A1, CYP2D6, EGR1, SLC9A1
Peripheral membrane protein 2 ACHE, CYP1A1
Endosome membrane 1 SLC6A4
Endoplasmic reticulum membrane 2 CYP1A1, CYP2D6
Mitochondrion membrane 1 MAOA
Nucleus 6 ACHE, CASP3, CASP8, EGR1, FOS, MPO
cytosol 6 CA1, CASP3, CASP8, CAT, FOS, MAOA
dendrite 2 HTR1A, HTR2A
nucleoplasm 7 ATP2B1, CASP3, CASP8, EGR1, FOS, MPO, SLC9A1
RNA polymerase II transcription regulator complex 1 FOS
Cell membrane 7 ACHE, ATP2B1, CNR1, HTR1A, HTR2A, SLC6A4, SLC9A1
Cytoplasmic side 1 MAOA
lamellipodium 2 CASP8, SLC9A1
Cell projection, axon 2 CNR1, HTR2A
Multi-pass membrane protein 7 ATP2B1, CACNA1I, CNR1, HTR1A, HTR2A, SLC6A4, SLC9A1
Synapse 5 ACHE, ATP2B1, CRH, HTR1A, SLC6A4
cell surface 2 ACHE, SLC9A1
dendritic shaft 1 HTR2A
glutamatergic synapse 4 ATP2B1, CASP3, CNR1, HTR2A
Golgi apparatus 1 ACHE
growth cone 1 CNR1
mitochondrial inner membrane 1 CYP1A1
neuromuscular junction 1 ACHE
neuronal cell body 2 CASP3, HTR2A
presynaptic membrane 4 ATP2B1, CNR1, HTR2A, SLC6A4
Lysosome 1 MPO
Presynapse 3 CNR1, HTR2A, SLC6A4
plasma membrane 8 ACHE, ATP2B1, CACNA1I, CNR1, HTR1A, HTR2A, SLC6A4, SLC9A1
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ACHE, ATP2B1, CACNA1I, CAT, CYP2D6, MAOA, SLC6A4, SLC9A1
apical plasma membrane 1 SLC9A1
axon 2 CNR1, HTR2A
basolateral plasma membrane 2 ATP2B1, SLC9A1
caveola 1 HTR2A
extracellular exosome 5 ATP2B1, CA1, CAT, MPO, SLC9A1
endoplasmic reticulum 2 CYP2D6, FOS
extracellular space 3 ACHE, CRH, MPO
perinuclear region of cytoplasm 2 ACHE, SLC9A1
intercalated disc 1 SLC9A1
mitochondrion 6 CASP8, CAT, CYP1A1, CYP2D6, MAOA, SLC9A1
protein-containing complex 2 CASP8, CAT
intracellular membrane-bounded organelle 5 ATP2B1, CAT, CYP1A1, CYP2D6, MPO
Microsome membrane 2 CYP1A1, CYP2D6
postsynaptic density 1 CASP3
Secreted 2 ACHE, CRH
extracellular region 4 ACHE, CAT, CRH, MPO
Mitochondrion outer membrane 2 CNR1, MAOA
Single-pass membrane protein 2 CYP2D6, MAOA
mitochondrial outer membrane 3 CASP8, CNR1, MAOA
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
varicosity 1 CRH
actin cytoskeleton 1 CNR1
T-tubule 1 SLC9A1
neuronal dense core vesicle lumen 1 CRH
perikaryon 1 CRH
cytoplasmic vesicle 1 HTR2A
postsynaptic membrane 2 HTR2A, SLC6A4
Cell projection, lamellipodium 1 CASP8
Mitochondrion inner membrane 1 CYP1A1
Membrane raft 3 CNR1, SLC6A4, SLC9A1
Cell junction, focal adhesion 1 SLC6A4
focal adhesion 3 CAT, SLC6A4, SLC9A1
GABA-ergic synapse 1 CNR1
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 MPO
lateral plasma membrane 1 ATP2B1
Cell projection, neuron projection 1 SLC6A4
neuron projection 1 SLC6A4
chromatin 2 EGR1, FOS
cell projection 1 ATP2B1
cytoskeleton 1 CASP8
Basolateral cell membrane 2 ATP2B1, SLC9A1
Lipid-anchor, GPI-anchor 1 ACHE
Endomembrane system 1 SLC6A4
Membrane, caveola 1 HTR2A
cell body fiber 1 HTR2A
Cell projection, dendrite 2 HTR1A, HTR2A
Presynaptic cell membrane 1 ATP2B1
cell body 1 CASP8
side of membrane 1 ACHE
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
nuclear matrix 1 FOS
voltage-gated calcium channel complex 1 CACNA1I
azurophil granule lumen 1 MPO
immunological synapse 1 ATP2B1
Single-pass type IV membrane protein 1 MAOA
neurofilament 1 HTR2A
phagocytic vesicle lumen 1 MPO
synaptic cleft 1 ACHE
protein-DNA complex 1 FOS
CD95 death-inducing signaling complex 1 CASP8
death-inducing signaling complex 2 CASP3, CASP8
ripoptosome 1 CASP8
transcription factor AP-1 complex 1 FOS
catalase complex 1 CAT
photoreceptor ribbon synapse 1 ATP2B1
cation-transporting ATPase complex 1 SLC9A1
[Isoform H]: Cell membrane 1 ACHE
G protein-coupled serotonin receptor complex 1 HTR2A
serotonergic synapse 1 SLC6A4


文献列表

  • Eleanor White, Tom Kennedy, Simon Ruffell, Daniel Perkins, Jerome Sarris. Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review. International journal of toxicology. 2024 May; 43(3):327-339. doi: 10.1177/10915818241230916. [PMID: 38363085]
  • Ayesha Khanum, Yamin Bibi, Ilham Khan, Ghazala Mustafa, Kotb A Attia, Arif Ahmed Mohammed, Seung Hwan Yang, Abdul Qayyum. Molecular docking of bioactive compounds extracted and purified from selected medicinal plant species against covid-19 proteins and in vitro evaluation. Scientific reports. 2024 02; 14(1):3736. doi: 10.1038/s41598-024-54470-6. [PMID: 38355953]
  • Phumudzo P Tshikhudo, Tafadzwanashe Mabhaudhi, Neil A Koorbanally, Fhatuwani N Mudau, Edgardo Oscar Avendaño Caceres, Dragos Popa, Daniela Calina, Javad Sharifi-Rad. Anticancer Potential of β-Carboline Alkaloids: An Updated Mechanistic Overview. Chemistry & biodiversity. 2023 Dec; ?(?):e202301263. doi: 10.1002/cbdv.202301263. [PMID: 38108650]
  • Ahmed H Abdelazim, Majed A Algarni, Atiah H Almalki. Innovative spectrofluorometric method for determination of harmaline and harmine in different matrices. Scientific reports. 2023 11; 13(1):19951. doi: 10.1038/s41598-023-46041-y. [PMID: 37968310]
  • Akram Hegazy, Sara H Mahmoud, Yaseen A M M Elshaier, Noura M Abo Shama, Nasr Fawzy Nasr, M A Ali, Assem Mohamed El-Shazly, Islam Mostafa, Ahmed Mostafa. Antiviral activities of plant-derived indole and β-carboline alkaloids against human and avian influenza viruses. Scientific reports. 2023 Jan; 13(1):1612. doi: 10.1038/s41598-023-27954-0. [PMID: 36709362]
  • Sakineh Alijanpour, Zahra Ghasemzadeh, Mohaddeseh Ebrahimi-Ghiri, Mohammad-Reza Zarrindast. Basolateral amygdala cannabinoid CB1 receptors mediate the antinociceptive activity of harmaline in adolescent male mice. Physiology & behavior. 2022 10; 254(?):113886. doi: 10.1016/j.physbeh.2022.113886. [PMID: 35718215]
  • Mohsen Rashidi, Elham Mahmoudian, Sepideh Mirzaei, Seyadeh Narges Mazloomi, Ali Bazi, Hossein Azadeh, Mobina Mozaffari. Harmaline downregulates angiogenesis markers and suppresses the growth of 4T1 breast cancer cells in vivo and in vitro. Chemico-biological interactions. 2022 Sep; 365(?):110087. doi: 10.1016/j.cbi.2022.110087. [PMID: 35963316]
  • Sara Álvarez-Rodríguez, David López-González, Manuel J Reigosa, Fabrizio Araniti, Adela M Sánchez-Moreiras. Ultrastructural and hormonal changes related to harmaline-induced treatment in Arabidopsis thaliana (L.) Heynh. root meristem. Plant physiology and biochemistry : PPB. 2022 May; 179(?):78-89. doi: 10.1016/j.plaphy.2022.03.022. [PMID: 35325658]
  • Mohammad Shabani, Reyhaneh Naderi. Phytohormone abscisic acid elicits positive effects on harmaline-induced cognitive and motor disturbances in a rat model of essential tremor. Brain and behavior. 2022 05; 12(5):e2564. doi: 10.1002/brb3.2564. [PMID: 35591769]
  • Beatriz Werneck Lopes Santos, Daniel Carneiro Moreira, Tatiana Karla Dos Santos Borges, Eloisa Dutra Caldas. Components of Banisteriopsis caapi, a Plant Used in the Preparation of the Psychoactive Ayahuasca, Induce Anti-Inflammatory Effects in Microglial Cells. Molecules (Basel, Switzerland). 2022 Apr; 27(8):. doi: 10.3390/molecules27082500. [PMID: 35458698]
  • You-Xu Wang, Ning Cao, Hui-Da Guan, Xue-Mei Cheng, Chang-Hong Wang. Heme peroxidases are responsible for the dehydrogenation and oxidation metabolism of harmaline into harmine. Chinese journal of natural medicines. 2022 Mar; 20(3):194-201. doi: 10.1016/s1875-5364(22)60151-1. [PMID: 35369963]
  • Cheng-Peng Sun, Jing Yi, Fan Wei, Xia Lv, Sa Deng, Bao-Jing Zhang, Wen-Yu Zhao, Xiao-Chi Ma. UV-light-driven photooxidation of harmaline catalyzed by riboflavin: Product characterization and mechanisms. Fitoterapia. 2021 Nov; 155(?):105054. doi: 10.1016/j.fitote.2021.105054. [PMID: 34626737]
  • Rofida A Saleh, Tarek F Eissa, Dalaal M Abdallah, Muhammed A Saad, Hanan S El-Abhar. Peganum harmala enhanced GLP-1 and restored insulin signaling to alleviate AlCl3-induced Alzheimer-like pathology model. Scientific reports. 2021 06; 11(1):12040. doi: 10.1038/s41598-021-90545-4. [PMID: 34103557]
  • Negar Sadegh, Arash Asfaram, Hamedreza Javadian, Hedayat Haddadi, Ebrahim Sharifpour. Ultrasound-assisted solid phase microextraction-HPLC method based on Fe3O4@SiO2-NH2-molecularly imprinted polymer magnetic nano-sorbent for rapid and efficient extraction of harmaline from Peganum harmala extract. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2021 May; 1171(?):122640. doi: 10.1016/j.jchromb.2021.122640. [PMID: 33743514]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Helle Kaasik, Rita C Z Souza, Flávia S Zandonadi, Luís Fernando Tófoli, Alessandra Sussulini. Chemical Composition of Traditional and Analog Ayahuasca. Journal of psychoactive drugs. 2021 Jan; 53(1):65-75. doi: 10.1080/02791072.2020.1815911. [PMID: 32896230]
  • Laura Lewerenz, Tahani Hijazin, Sara Abouzeid, Robert Hänsch, Dirk Selmar. Pilot study on the uptake and modification of harmaline in acceptor plants: An innovative approach to visualize the interspecific transfer of natural products. Phytochemistry. 2020 Jun; 174(?):112362. doi: 10.1016/j.phytochem.2020.112362. [PMID: 32229335]
  • Silvia Biggi, Michael Pancher, Claudia Stincardini, Silvia Luotti, Tania Massignan, Andrea Dalle Vedove, Andrea Astolfi, Pamela Gatto, Graziano Lolli, Maria Letizia Barreca, Valentina Bonetto, Valentina Adami, Emiliano Biasini. Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface. Journal of neurochemistry. 2020 01; 152(1):136-150. doi: 10.1111/jnc.14805. [PMID: 31264722]
  • Bo Jiang, Liyuan Meng, Nan Zou, Hanxue Wang, Shuping Li, Lifeng Huang, Xuemei Cheng, Zhengtao Wang, Wansheng Chen, Changhong Wang. Mechanism-based pharmacokinetics-pharmacodynamics studies of harmine and harmaline on neurotransmitters regulatory effects in healthy rats: Challenge on monoamine oxidase and acetylcholinesterase inhibition. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Sep; 62(?):152967. doi: 10.1016/j.phymed.2019.152967. [PMID: 31154274]
  • Rita C Z Souza, Flávia S Zandonadi, Donizete P Freitas, Luís F F Tófoli, Alessandra Sussulini. Validation of an analytical method for the determination of the main ayahuasca active compounds and application to real ayahuasca samples from Brazil. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2019 Aug; 1124(?):197-203. doi: 10.1016/j.jchromb.2019.06.014. [PMID: 31220748]
  • Yan Zhang, Futao Liu, Hao Xiao, Xinyue Yao, Genxun Li, Seok Rye Choi, Karl Ploessl, Zhihao Zha, Lin Zhu, Hank F Kung. Fluorine-18 labeled diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain. Nuclear medicine and biology. 2018 11; 66(?):1-9. doi: 10.1016/j.nucmedbio.2018.06.008. [PMID: 30096380]
  • Paromita Bhattacharjee, Tapas Ghosh, Sarita Sarkar, Prateek Pandya, Kakali Bhadra. Binding affinity and in vitro cytotoxicity of harmaline targeting different motifs of nucleic acids: An ultimate drug designing approach. Journal of molecular recognition : JMR. 2018 04; 31(4):. doi: 10.1002/jmr.2687. [PMID: 29243872]
  • Sarita Sarkar, Kakali Bhadra. Therapeutic Role of Harmalol Targeting Nucleic Acids: Biophysical Perspective and in vitro Cytotoxicity. Mini reviews in medicinal chemistry. 2018; 18(19):1624-1639. doi: 10.2174/1389557518666171211164830. [PMID: 29231137]
  • Jose A Morales-García, Mario de la Fuente Revenga, Sandra Alonso-Gil, María Isabel Rodríguez-Franco, Amanda Feilding, Ana Perez-Castillo, Jordi Riba. The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro. Scientific reports. 2017 07; 7(1):5309. doi: 10.1038/s41598-017-05407-9. [PMID: 28706205]
  • M A Tabari, M R Youssefi, A A Moghadamnia. Antitrichomonal activity of Peganum harmala alkaloid extract against trichomoniasis in pigeon (Columba livia domestica). British poultry science. 2017 Jun; 58(3):236-241. doi: 10.1080/00071668.2017.1280725. [PMID: 28084792]
  • Shuping Li, Liang Teng, Wei Liu, Xuemei Cheng, Bo Jiang, Zhengtao Wang, Changhong Wang. Interspecies metabolic diversity of harmaline and harmine in in vitro 11 mammalian liver microsomes. Drug testing and analysis. 2017 May; 9(5):754-768. doi: 10.1002/dta.2028. [PMID: 27377954]
  • Marcos Tascón, Fernando Benavente, Nora M Vizioli, Leonardo G Gagliardi. A rapid and simple method for the determination of psychoactive alkaloids by CE-UV: application to Peganum Harmala seed infusions. Drug testing and analysis. 2017 Apr; 9(4):596-602. doi: 10.1002/dta.1989. [PMID: 27377797]
  • Hina Siddiqui, Sehar Tasneem, Saba Farooq, Amtul Sami, Atta-Ur Rahman, Muhammad I Choudhary. Harmaline and its Derivatives Against the Infectious Multi-Drug Resistant Escherichia coli. Medicinal chemistry (Shariqah (United Arab Emirates)). 2017; 13(5):465-476. doi: 10.2174/1573406413666170125113832. [PMID: 28124613]
  • Xiaofei Shang, Xiao Guo, Bing Li, Hu Pan, Jiyu Zhang, Yu Zhang, Xiaolou Miao. Microwave-assisted extraction of three bioactive alkaloids from Peganum harmala L. and their acaricidal activity against Psoroptes cuniculi in vitro. Journal of ethnopharmacology. 2016 Nov; 192(?):350-361. doi: 10.1016/j.jep.2016.07.057. [PMID: 27452655]
  • Elzalina R Soares, Felipe M A da Silva, Richardson A de Almeida, Bruna R de Lima, Francinaldo A da Silva Filho, Andersson Barison, Hector H F Koolen, Maria Lúcia B Pinheiro, Afonso D L de Souza. Direct infusion ESI-IT-MSn alkaloid profile and isolation of tetrahydroharman and other alkaloids from Bocageopsis pleiosperma maas (Annonaceae). Phytochemical analysis : PCA. 2015 Sep; 26(5):339-45. doi: 10.1002/pca.2568. [PMID: 26108161]
  • Fabienne Gourand, Nahid Amini, Zhisheng Jia, Sharon Stone-Elander, Denis Guilloteau, Louisa Barré, Christer Halldin. [11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET). PloS one. 2015; 10(9):e0137160. doi: 10.1371/journal.pone.0137160. [PMID: 26367261]
  • Chunnuan Deng, Hua Shao, Xiangliang Pan, Shuzhi Wang, Daoyong Zhang. Herbicidal effects of harmaline from Peganum harmala on photosynthesis of Chlorella pyrenoidosa: probed by chlorophyll fluorescence and thermoluminescence. Pesticide biochemistry and physiology. 2014 Oct; 115(?):23-31. doi: 10.1016/j.pestbp.2014.08.002. [PMID: 25307462]
  • Sudhakar Manda, Shabana I Khan, Surendra K Jain, Shabber Mohammed, Babu L Tekwani, Ikhlas A Khan, Ram A Vishwakarma, Sandip B Bharate. Synthesis, antileishmanial and antitrypanosomal activities of N-substituted tetrahydro-β-carbolines. Bioorganic & medicinal chemistry letters. 2014 Aug; 24(15):3247-50. doi: 10.1016/j.bmcl.2014.06.030. [PMID: 24980054]
  • Farhan A Khan, Aneela Maalik, Zafar Iqbal, Imran Malik. Recent pharmacological developments in β-carboline alkaloid "harmaline". European journal of pharmacology. 2013 Dec; 721(1-3):391-4. doi: 10.1016/j.ejphar.2013.05.003. [PMID: 23707188]
  • Lei Zhang, Liang Teng, Can Gong, Wei Liu, Xuemei Cheng, Shenghua Gu, Zhongping Deng, Zhengtao Wang, Changhong Wang. Simultaneous determination of harmine, harmaline and their metabolites harmol and harmalol in beagle dog plasma by UPLC-ESI-MS/MS and its application to a pharmacokinetic study. Journal of pharmaceutical and biomedical analysis. 2013 Nov; 85(?):162-8. doi: 10.1016/j.jpba.2013.07.019. [PMID: 23948761]
  • Seong-Ki Lee, Walter F Boron, Mark D Parker. Substrate specificity of the electrogenic sodium/bicarbonate cotransporter NBCe1-A (SLC4A4, variant A) from humans and rabbits. American journal of physiology. Renal physiology. 2013 Apr; 304(7):F883-99. doi: 10.1152/ajprenal.00612.2012. [PMID: 23324180]
  • Hua Shao, Xiaoli Huang, Yuanming Zhang, Chi Zhang. Main alkaloids of Peganum harmala L. and their different effects on dicot and monocot crops. Molecules (Basel, Switzerland). 2013 Feb; 18(3):2623-34. doi: 10.3390/molecules18032623. [PMID: 23446919]
  • Nashwa Jarkas. Fluorinated diaryl sulfides. Current topics in medicinal chemistry. 2013; 13(8):936-43. doi: 10.2174/1568026611313080006. [PMID: 23590166]
  • Ting Zhao, Shan-Song Zheng, Bin-Feng Zhang, Yuan-Yuan Li, S W Annie Bligh, Chang-Hong Wang, Zheng-Tao Wang. Metabolic pathways of the psychotropic-carboline alkaloids, harmaline and harmine, by liquid chromatography/mass spectrometry and NMR spectroscopy. Food chemistry. 2012 Sep; 134(2):1096-105. doi: 10.1016/j.foodchem.2012.03.024. [PMID: 23107733]
  • Bharathi Avula, Yan-Hong Wang, Chidananda Swamy Rumalla, Troy J Smillie, Ikhlas A Khan. Simultaneous determination of alkaloids and flavonoids from aerial parts of Passiflora species and dietary supplements using UPLC-UV-MS and HPTLC. Natural product communications. 2012 Sep; 7(9):1177-80. doi: . [PMID: 23074901]
  • Bahram Hemmateenejad, Mojtaba Shamsipur, Fayezeh Samari, Taghi Khayamian, Malihe Ebrahimi, Zahra Rezaei. Combined fluorescence spectroscopy and molecular modeling studies on the interaction between harmalol and human serum albumin. Journal of pharmaceutical and biomedical analysis. 2012 Aug; 67-68(?):201-8. doi: 10.1016/j.jpba.2012.04.012. [PMID: 22560122]
  • Jordi Riba, Ethan H McIlhenny, Marta Valle, José Carlos Bouso, Steven A Barker. Metabolism and disposition of N,N-dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca. Drug testing and analysis. 2012 Jul; 4(7-8):610-6. doi: 10.1002/dta.1344. [PMID: 22514127]
  • Xuesheng Zhang, Fu Liu, Binyuan Chen, Ying Li, Zunyao Wang. Acute and subacute oral toxicity of polychlorinated diphenyl sulfides in mice: determining LD50 and assessing the status of hepatic oxidative stress. Environmental toxicology and chemistry. 2012 Jul; 31(7):1485-93. doi: 10.1002/etc.1861. [PMID: 22549922]
  • José Carlos Bouso, Débora González, Sabela Fondevila, Marta Cutchet, Xavier Fernández, Paulo César Ribeiro Barbosa, Miguel Ángel Alcázar-Córcoles, Wladimyr Sena Araújo, Manel J Barbanoj, Josep Maria Fábregas, Jordi Riba. Personality, psychopathology, life attitudes and neuropsychological performance among ritual users of Ayahuasca: a longitudinal study. PloS one. 2012; 7(8):e42421. doi: 10.1371/journal.pone.0042421. [PMID: 22905130]
  • Steven Maranz. An alternative paradigm for the role of antimalarial plants in Africa. TheScientificWorldJournal. 2012; 2012(?):978913. doi: 10.1100/2012/978913. [PMID: 22593717]
  • Ting Zhao, Yu-qi He, Jun Wang, Ke-min Ding, Chang-hong Wang, Zheng-tao Wang. Inhibition of human cytochrome P450 enzymes 3A4 and 2D6 by β-carboline alkaloids, harmine derivatives. Phytotherapy research : PTR. 2011 Nov; 25(11):1671-7. doi: 10.1002/ptr.3458. [PMID: 21433154]
  • Fatta B Nahab, Loretta Wittevrongel, Dominic Ippolito, Camilo Toro, George J Grimes, Judith Starling, Gopal Potti, Dietrich Haubenberger, Daniel Bowen, Peter Buchwald, Chuanhui Dong, Daniel Kalowitz, Mark Hallett. An open-label, single-dose, crossover study of the pharmacokinetics and metabolism of two oral formulations of 1-octanol in patients with essential tremor. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2011 Oct; 8(4):753-62. doi: 10.1007/s13311-011-0045-1. [PMID: 21594724]
  • Christine A Strick, Cheryl Li, Liam Scott, Brian Harvey, Mihály Hajós, Stefanus J Steyn, Mary A Piotrowski, Larry C James, James T Downs, Brian Rago, Stacey L Becker, Ayman El-Kattan, Youfen Xu, Alan H Ganong, F David Tingley, Andres D Ramirez, Patricia A Seymour, Victor Guanowsky, Mark J Majchrzak, Carol B Fox, Christopher J Schmidt, Allen J Duplantier. Modulation of NMDA receptor function by inhibition of D-amino acid oxidase in rodent brain. Neuropharmacology. 2011 Oct; 61(5-6):1001-15. doi: 10.1016/j.neuropharm.2011.06.029. [PMID: 21763704]
  • Muhammad Rizwan-ul-Haq, Liang Gong, Meiying Hu, Jianjun Luo. Apolipophorin III and transmission electron microscopy as toxicity indicators for harmaline and tea saponin in Spodoptera exigua (Noctuidae: Lepidoptera). Chemosphere. 2011 Oct; 85(6):995-1001. doi: 10.1016/j.chemosphere.2011.06.089. [PMID: 21783224]
  • J C Winter, D J Amorosi, Kenner C Rice, Kejun Cheng, Ai-Ming Yu. Stimulus control by 5-methoxy-N,N-dimethyltryptamine in wild-type and CYP2D6-humanized mice. Pharmacology, biochemistry, and behavior. 2011 Sep; 99(3):311-5. doi: 10.1016/j.pbb.2011.05.015. [PMID: 21624387]
  • Hamid-Reza Adhami, Hassan Farsam, Liselotte Krenn. Screening of medicinal plants from Iranian traditional medicine for acetylcholinesterase inhibition. Phytotherapy research : PTR. 2011 Aug; 25(8):1148-52. doi: 10.1002/ptr.3409. [PMID: 21287652]
  • Nahida Tabassum, Feroz Ahmad. Role of natural herbs in the treatment of hypertension. Pharmacognosy reviews. 2011 Jan; 5(9):30-40. doi: 10.4103/0973-7847.79097. [PMID: 22096316]
  • Sun Young Park, Young Hun Kim, Young Hee Kim, Geuntae Park, Sang-Joon Lee. Beta-carboline alkaloids harmaline and harmalol induce melanogenesis through p38 mitogen-activated protein kinase in B16F10 mouse melanoma cells. BMB reports. 2010 Dec; 43(12):824-9. doi: 10.5483/bmbrep.2010.43.12.824. [PMID: 21189160]
  • Gislaine Z Réus, Roberto B Stringari, Bruna de Souza, Fabrícia Petronilho, Felipe Dal-Pizzol, Jaime E Hallak, Antônio W Zuardi, José A Crippa, João Quevedo. Harmine and imipramine promote antioxidant activities in prefrontal cortex and hippocampus. Oxidative medicine and cellular longevity. 2010 Sep; 3(5):325-31. doi: 10.4161/oxim.3.5.13109. [PMID: 21150338]
  • Kemin Ding, Li Liu, Xuemei Cheng, Changhong Wang, Zhengtao Wang. [Investigation on representation methods of dissolubility property of total alkaloid extract from Peganum harmala]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2010 Sep; 35(17):2250-3. doi: . [PMID: 21137330]
  • Mohamed A M El Gendy, Vishwa Somayaji, Ayman O S El-Kadi. Peganum harmala L. is a candidate herbal plant for preventing dioxin mediated effects. Planta medica. 2010 May; 76(7):671-7. doi: 10.1055/s-0029-1240633. [PMID: 19941261]
  • Yan-Hong Wang, Volodymyr Samoylenko, Babu L Tekwani, Ikhlas A Khan, Loren S Miller, Narayan D Chaurasiya, Md Mostafizur Rahman, Lalit M Tripathi, Shabana I Khan, Vaishali C Joshi, Frank T Wigger, Ilias Muhammad. Composition, standardization and chemical profiling of Banisteriopsis caapi, a plant for the treatment of neurodegenerative disorders relevant to Parkinson's disease. Journal of ethnopharmacology. 2010 Apr; 128(3):662-71. doi: 10.1016/j.jep.2010.02.013. [PMID: 20219660]
  • T Herraiz, D González, C Ancín-Azpilicueta, V J Arán, H Guillén. beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2010 Mar; 48(3):839-45. doi: 10.1016/j.fct.2009.12.019. [PMID: 20036304]
  • Volodymyr Samoylenko, Md Mostafizur Rahman, Babu L Tekwani, Lalit M Tripathi, Yan-Hong Wang, Shabana I Khan, Ikhlas A Khan, Loren S Miller, Vaishali C Joshi, Ilias Muhammad. Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson's disease. Journal of ethnopharmacology. 2010 Feb; 127(2):357-67. doi: 10.1016/j.jep.2009.10.030. [PMID: 19879939]
  • Kacem Rharrabe, Fouad Sayan, René Lafont. Dietary effects of four phytoecdysteroids on growth and development of the Indian meal moth, Plodia interpunctella. Journal of insect science (Online). 2010; 10(?):13. doi: 10.1673/031.010.1301. [PMID: 20575744]
  • Xi-yuan Zheng, Zi-jia Zhang, Gui-xin Chou, Tao Wu, Xue-mei Cheng, Chang-hong Wang, Zheng-tao Wang. Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay. Archives of pharmacal research. 2009 Sep; 32(9):1245-51. doi: 10.1007/s12272-009-1910-x. [PMID: 19784581]
  • Mastura Mohtar, Saiful Azmi Johari, Abdul Rashid Li, Mazurah Mohamed Isa, Shuhaimi Mustafa, Abdul Manaf Ali, Dayang Fredalina Basri. Inhibitory and resistance-modifying potential of plant-based alkaloids against methicillin-resistant Staphylococcus aureus (MRSA). Current microbiology. 2009 Aug; 59(2):181-6. doi: 10.1007/s00284-009-9416-9. [PMID: 19475447]
  • Kristian Björnstad, Peter Hultén, Olof Beck, Anders Helander. Bioanalytical and clinical evaluation of 103 suspected cases of intoxications with psychoactive plant materials. Clinical toxicology (Philadelphia, Pa.). 2009 Jul; 47(6):566-72. doi: 10.1080/15563650903037181. [PMID: 19586355]
  • Akihisa Abe, Hiroyuki Yamada. Harmol induces apoptosis by caspase-8 activation independently of Fas/Fas ligand interaction in human lung carcinoma H596 cells. Anti-cancer drugs. 2009 Jun; 20(5):373-81. doi: 10.1097/cad.0b013e32832a2dd9. [PMID: 19318910]
  • Maiko Kawamura, Ruri Kikura-Hanajiri, Yukihiro Goda. [Simple and rapid screening for psychotropic natural products using Direct Analysis in Real Time (DART)-TOFMS]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2009 Jun; 129(6):719-25. doi: 10.1248/yakushi.129.719. [PMID: 19483414]
  • Ji-Hyun Im, Yong-Ri Jin, Jung-Jin Lee, Ji-Yeon Yu, Xiang-Hua Han, Se-Hyuk Im, Jin Tae Hong, Hwan-Soo Yoo, Myoung-Yun Pyo, Yeo-Pyo Yun. Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation. Vascular pharmacology. 2009 May; 50(5-6):147-52. doi: 10.1016/j.vph.2008.11.008. [PMID: 19073282]
  • Kristian Björnstad, Olof Beck, Anders Helander. A multi-component LC-MS/MS method for detection of ten plant-derived psychoactive substances in urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 Apr; 877(11-12):1162-8. doi: 10.1016/j.jchromb.2009.03.004. [PMID: 19332394]
  • Jochen Beyer, Olaf H Drummer, Hans H Maurer. Analysis of toxic alkaloids in body samples. Forensic science international. 2009 Mar; 185(1-3):1-9. doi: 10.1016/j.forsciint.2008.12.006. [PMID: 19147309]
  • Ana Paula Salum Pires, Carolina Dizioli Rodrigues De Oliveira, Sidnei Moura, Felipe Augusto Dörr, Wagner Abreu E Silva, Mauricio Yonamine. Gas chromatographic analysis of dimethyltryptamine and beta-carboline alkaloids in ayahuasca, an Amazonian psychoactive plant beverage. Phytochemical analysis : PCA. 2009 Mar; 20(2):149-53. doi: 10.1002/pca.1110. [PMID: 19140116]
  • A Movafeghi, M Abedini, F Fathiazad, M Aliasgharpour, Y Omidi. Floral nectar composition of Peganum harmala L. Natural product research. 2009; 23(3):301-8. doi: 10.1080/14786410802076291. [PMID: 19235031]
  • Najma Arshad, Karin Zitterl-Eglseer, Shahida Hasnain, Michael Hess. Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry. Phytotherapy research : PTR. 2008 Nov; 22(11):1533-8. doi: 10.1002/ptr.2528. [PMID: 18814210]
  • Cristiana Gambelunghe, Kyriaki Aroni, Riccardo Rossi, Luca Moretti, Mauro Bacci. Identification of N,N-dimethyltryptamine and beta-carbolines in psychotropic ayahuasca beverage. Biomedical chromatography : BMC. 2008 Oct; 22(10):1056-9. doi: 10.1002/bmc.1023. [PMID: 18506697]
  • Adil Astulla, Kazumasa Zaima, Yosuke Matsuno, Yusuke Hirasawa, Wiwied Ekasari, Aty Widyawaruyanti, Noor Cholies Zaini, Hiroshi Morita. Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities. Journal of natural medicines. 2008 Oct; 62(4):470-2. doi: 10.1007/s11418-008-0259-7. [PMID: 18523842]
  • Aslihan Yuruktumen, Sevilay Karaduman, Fecri Bengi, John Fowler. Syrian rue tea: a recipe for disaster. Clinical toxicology (Philadelphia, Pa.). 2008 Sep; 46(8):749-52. doi: 10.1080/15563650701323205. [PMID: 18803088]
  • Giampietro Frison, Donata Favretto, Flavio Zancanaro, Giorgio Fazzin, Santo Davide Ferrara. A case of beta-carboline alkaloid intoxication following ingestion of Peganum harmala seed extract. Forensic science international. 2008 Aug; 179(2-3):e37-43. doi: 10.1016/j.forsciint.2008.05.003. [PMID: 18603389]
  • V Caretti, D Stoffers, A Winogrodzka, I-U Isaias, G Costantino, G Pezzoli, C Ferrarese, A Antonini, E-Ch Wolters, J Booij. Loss of thalamic serotonin transporters in early drug-naïve Parkinson's disease patients is associated with tremor: an [(123)I]beta-CIT SPECT study. Journal of neural transmission (Vienna, Austria : 1996). 2008 May; 115(5):721-9. doi: 10.1007/s00702-007-0015-2. [PMID: 18335163]
  • Ede Frecska. Ayahuasca versus violence--a case report. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. 2008 May; 10(2):103-6. doi: ". [PMID: 18959142]
  • Nachwa Jarkas, Ronald J Voll, Larry Williams, John R Votaw, Mike Owens, Mark M Goodman. Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands. Journal of medicinal chemistry. 2008 Jan; 51(2):271-81. doi: 10.1021/jm0707929. [PMID: 18085744]
  • Nathaniel Bletter. A quantitative synthesis of the medicinal ethnobotany of the Malinké of Mali and the Asháninka of Peru, with a new theoretical framework. Journal of ethnobiology and ethnomedicine. 2007 Dec; 3(?):36. doi: 10.1186/1746-4269-3-36. [PMID: 18053260]
  • R G Santos, J Landeira-Fernandez, R J Strassman, V Motta, A P M Cruz. Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members. Journal of ethnopharmacology. 2007 Jul; 112(3):507-13. doi: 10.1016/j.jep.2007.04.012. [PMID: 17532158]
  • Farhad Zaker, Arezo Oody, Alireza Arjmand. A study on the antitumoral and differentiation effects of peganum harmala derivatives in combination with ATRA on leukaemic cells. Archives of pharmacal research. 2007 Jul; 30(7):844-9. doi: 10.1007/bf02978835. [PMID: 17703736]
  • Hicham Berrougui, Carmen Martín-Cordero, Abdelouahed Khalil, Mohammed Hmamouchi, Abdelkader Ettaib, Elisa Marhuenda, María Dolores Herrera. Vasorelaxant effects of harmine and harmaline extracted from Peganum harmala L. seeds in isolated rat aorta. Pharmacological research. 2006 Aug; 54(2):150-7. doi: 10.1016/j.phrs.2006.04.001. [PMID: 16750635]
  • Hicham Berrougui, Maxim Isabelle, Martin Cloutier, Mohammed Hmamouchi, Abdelouahed Khalil. Protective effects of Peganum harmala L. extract, harmine and harmaline against human low-density lipoprotein oxidation. The Journal of pharmacy and pharmacology. 2006 Jul; 58(7):967-74. doi: 10.1211/jpp.58.7.0012. [PMID: 16805957]
  • Julien Fiot, Souleymane Sanon, Nadine Azas, Valérie Mahiou, Olivia Jansen, Luc Angenot, Guy Balansard, Evelyne Ollivier. Phytochemical and pharmacological study of roots and leaves of Guiera senegalensis J.F. Gmel (Combretaceae). Journal of ethnopharmacology. 2006 Jun; 106(2):173-8. doi: 10.1016/j.jep.2005.12.030. [PMID: 16443341]
  • Johnny Vercouillie, Sylvie Mavel, Laurent Galineau, Tiziana Ragusa, Robert Innis, Michael Kassiou, Sylvie Chalon, Frédéric Dollé, Jean-Claude Besnard, Denis Guilloteau, Patrick Emond. Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands. Bioorganic & medicinal chemistry letters. 2006 Mar; 16(5):1297-300. doi: 10.1016/j.bmcl.2005.11.066. [PMID: 16337793]
  • R Kikura-Hanajiri, M Hayashi, K Saisho, Y Goda. Simultaneous determination of nineteen hallucinogenic tryptamines/beta-calbolines and phenethylamines using gas chromatography-mass spectrometry and liquid chromatography-electrospray ionisation-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Oct; 825(1):29-37. doi: 10.1016/j.jchromb.2005.01.041. [PMID: 16154520]
  • J C Callaway. Fast and slow metabolizers of Hoasca. Journal of psychoactive drugs. 2005 Jun; 37(2):157-61. doi: 10.1080/02791072.2005.10399797. [PMID: 16149329]
  • J C Callaway, Glacus S Brito, Edison S Neves. Phytochemical analyses of Banisteriopsis caapi and Psychotria viridis. Journal of psychoactive drugs. 2005 Jun; 37(2):145-50. doi: 10.1080/02791072.2005.10399795. [PMID: 16149327]
  • J C Callaway. Various alkaloid profiles in decoctions of Banisteriopsis caapi. Journal of psychoactive drugs. 2005 Jun; 37(2):151-5. doi: 10.1080/02791072.2005.10399796. [PMID: 16149328]
  • Rawin Zayed, Michael Wink. Beta-carboline and quinoline alkaloids in root cultures and intact plants of Peganum harmala. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2005 May; 60(5-6):451-8. doi: 10.1515/znc-2005-5-614. [PMID: 16042347]
  • Ramón Aguiar, Michael Wink. Do naïve ruminants degrade alkaloids in the rumen?. Journal of chemical ecology. 2005 Apr; 31(4):761-87. doi: 10.1007/s10886-005-3543-y. [PMID: 16124250]
  • D Guilloteau, S Chalon. PET and SPECT exploration of central monoaminergic transporters for the development of new drugs and treatments in brain disorders. Current pharmaceutical design. 2005; 11(25):3237-45. doi: 10.2174/138161205774424744. [PMID: 16250852]
  • Ivo P Nnane, Lyaquat A Damani. Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole. Biomedical chromatography : BMC. 2005 Jan; 19(1):87-98. doi: 10.1002/bmc.421. [PMID: 15470701]
  • Alexander Storch, Yu-I Hwang, Debra A Gearhart, J Warren Beach, Edward J Neafsey, Michael A Collins, Johannes Schwarz. Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake. Journal of neurochemistry. 2004 May; 89(3):685-94. doi: 10.1111/j.1471-4159.2004.02397.x. [PMID: 15086525]
  • Hamid Reza Monsef, Ali Ghobadi, Mehrdad Iranshahi, Mohammad Abdollahi. Antinociceptive effects of Peganum harmala L. alkaloid extract on mouse formalin test. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 2004 Feb; 7(1):65-9. doi: ". [PMID: 15144736]
  • Jordi Riba, Marta Valle, Gloria Urbano, Mercedes Yritia, Adelaida Morte, Manel J Barbanoj. Human pharmacology of ayahuasca: subjective and cardiovascular effects, monoamine metabolite excretion, and pharmacokinetics. The Journal of pharmacology and experimental therapeutics. 2003 Jul; 306(1):73-83. doi: 10.1124/jpet.103.049882. [PMID: 12660312]
  • M J Schwarz, P J Houghton, S Rose, P Jenner, A D Lees. Activities of extract and constituents of Banisteriopsis caapi relevant to parkinsonism. Pharmacology, biochemistry, and behavior. 2003 Jun; 75(3):627-33. doi: 10.1016/s0091-3057(03)00129-1. [PMID: 12895680]
  • Aysen Muezzinoglu. A study of volatile organic sulfur emissions causing urban odors. Chemosphere. 2003 Apr; 51(4):245-52. doi: 10.1016/s0045-6535(02)00821-4. [PMID: 12604076]
  • Songbai Zhang, Akihiro Mizutani, Chihiro Hisatsune, Takayasu Higo, Hiroko Bannai, Tomohiro Nakayama, Mitsuharu Hattori, Katsuhiko Mikoshiba. Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells. The Journal of biological chemistry. 2003 Feb; 278(6):4048-56. doi: 10.1074/jbc.m209960200. [PMID: 12444087]