Tryptamine (BioDeep_00000000123)

 

Secondary id: BioDeep_00000399993, BioDeep_00000412404

natural product human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


2-(1H-indol-3-yl)ethan-1-amine

化学式: C10H12N2 (160.1)
中文名称: 色胺
谱图信息: 最多检出来源 Homo sapiens(blood) 15.78%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Tryptamine. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/tryptamine (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000000123). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=CN2)CCN
InChI: InChI=1/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2

描述信息

Tryptamine, also known as TrpN, is a catabolite of tryptophan converted by the gut microbiota. After absorption through the intestinal epithelium, tryptophan catabolites enter the bloodstream and are later excreted in the urine. Both Clostridium sp. and Ruminococcus sp. have been found to convert tryptophan into tryptamine (PMID: 30120222). Tryptamine is a monoamine compound that is a common precursor molecule to many hormones and neurotransmitters. Biosynthesis generally proceeds from the amino acid tryptophan, with tryptamine acting as a precursor for other compounds. Substitutions to the tryptamine molecule give rise to a group of compounds collectively known as tryptamines. The most well-known tryptamines are serotonin, an important neurotransmitter, and melatonin, a hormone involved in regulating the sleep-wake cycle. Tryptamine has been detected, but not quantified in, several different foods, such as onion-family vegetables, acerola, Japanese walnuts, custard apples, and green zucchinis. This could make tryptamine a potential biomarker for the consumption of these foods.
Tryptamine is an aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position. It has a role as a human metabolite, a plant metabolite and a mouse metabolite. It is an aminoalkylindole, an indole alkaloid, an aralkylamino compound and a member of tryptamines. It is a conjugate base of a tryptaminium.
Tryptamine is a natural product found in Mus musculus, Prosopis glandulosa, and other organisms with data available.
Occurs widely in plants, especies Lens esculenta (lentil) and the fungi Coprinus micaceus (glistening ink cap)
An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.
KEIO_ID T031

同义名列表

63 个代谢物同义名

InChI=1/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H; 5-22-10-00045 (Beilstein Handbook Reference); (Amino-2 ethyl)-3 indole;3-Indoleethylamine; Tryptamine, Vetec(TM) reagent grade, 98\\%; 5E7B376B-5933-446C-9D88-661B5F480122; (Amino-2 ethyl)-3 indole [French]; Tryptamine, analytical standard; 2-(1H-Indol-3-Yl)Ethan-1-Amine; 2-(1H-indol-3-yl)-ethyl-amine; 2-(1H-Indol-3-yl)ethanamine #; 2-(1h-indol-3-yl) ethylamine; 2-(1H-INDOL-3-YL)-ETHYLAMINE; .beta.-(3-Indolyl)ethylamine; tryptamine monohydrochloride; 2-(1H-indol-3-yl)ethylamine; 2-(1H-Indol-3-yl)ethanamine; 3-(2-Aminoethyl)-1H-indole; beta-(3-Indolyl)ethylamine; 3-(beta-aminoethyl)-indole; Indole, 3-(2-aminoethyl)-; (Amino-2 ethyl)-3 indole; 2-(Indol-3-yl)ethylamine; 2-Indol-3-yl-aethylamin; 2-indol-3-yl-ethylamine; 3-(2-amino)ethyl indole; 2-(3-Indolyl)ethylamine; Β-(3-indolyl)ethylamine; 1H-Indole-3-ethanamine; 2-Indol-3-ylethylamine; 3-(2-aminoethyl)indole; 3-[2-Aminoethyl]indole; Tryptamine, free base; (3-Indolyl)ethylamine; 3-indolylethylamine; 3-Indoleethylamine; tryptamine sulfate; 3-Indoleethanamine; Indol-3-ethylamine; Spectrum5_001296; Spectrum2_000873; Tryptamine, 98\\%; Spectrum3_001890; Spectrum4_000850; TRYPTAMINE [MI]; Oprea1_870097; Lopac0_000061; DivK1c_000862; KBio2_000393; KBio2_002961; KBio1_000862; KBio3_002903; KBio2_005529; IDI1_000862; triptamine; Tryptamine; Tryptamin; TRPN; TSH; beta-3-Indolylethylamine hydrochloride; 3-(2-Aminoethyl)indole Hydrochloride; Tryptamine; Tryptamine; Tryptamine



数据库引用编号

35 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

473 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(464)

INOH(1)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(7)

PharmGKB(0)

197 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AANAT, AHR, CYP2D6, HTR4, INMT, PTGS2, WARS1
Peripheral membrane protein 3 ACHE, CYP1B1, PTGS2
Endosome membrane 2 HTR4, SLC6A4
Endoplasmic reticulum membrane 5 CYP1A2, CYP1B1, CYP2D6, PTGS2, TAAR1
Mitochondrion membrane 1 MAOA
Nucleus 3 ACHE, AHR, WARS1
cytosol 5 AANAT, AHR, INMT, MAOA, WARS1
dendrite 5 HTR1A, HTR2A, HTR2C, HTR4, MAOB
nucleoplasm 1 AHR
Cell membrane 8 ACHE, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, SLC6A4, TAAR1
Cytoplasmic side 2 MAOA, MAOB
Cleavage furrow 1 HTR3A
Cell projection, axon 1 HTR2A
Multi-pass membrane protein 7 HTR1A, HTR2A, HTR2C, HTR3A, HTR4, SLC6A4, TAAR1
Synapse 6 ACHE, HTR1A, HTR2C, HTR3A, HTR4, SLC6A4
cell surface 1 ACHE
dendritic shaft 1 HTR2A
glutamatergic synapse 2 HTR2A, HTR4
Golgi apparatus 1 ACHE
Golgi membrane 1 INS
neuromuscular junction 1 ACHE
neuronal cell body 2 HTR2A, MAOB
postsynapse 2 HTR3A, HTR4
presynaptic membrane 2 HTR2A, SLC6A4
Presynapse 2 HTR2A, SLC6A4
endosome 1 HTR4
plasma membrane 9 ACHE, BCHE, HTR1A, HTR2A, HTR2C, HTR3A, HTR4, SLC6A4, TAAR1
Membrane 7 ACHE, CYP1B1, CYP2D6, HTR3A, HTR4, MAOA, SLC6A4
axon 1 HTR2A
caveola 2 HTR2A, PTGS2
extracellular exosome 1 WARS1
endoplasmic reticulum 2 CYP2D6, PTGS2
extracellular space 3 ACHE, BCHE, INS
perinuclear region of cytoplasm 2 AANAT, ACHE
mitochondrion 4 CYP1B1, CYP2D6, MAOA, MAOB
protein-containing complex 3 AHR, PTGS2, WARS1
intracellular membrane-bounded organelle 3 CYP1A2, CYP1B1, CYP2D6
Microsome membrane 4 CYP1A2, CYP1B1, CYP2D6, PTGS2
Secreted 3 ACHE, BCHE, INS
extracellular region 3 ACHE, BCHE, INS
Mitochondrion outer membrane 2 MAOA, MAOB
Single-pass membrane protein 2 CYP2D6, MAOA
mitochondrial outer membrane 2 MAOA, MAOB
Extracellular side 1 ACHE
transcription regulator complex 1 AHR
cytoplasmic vesicle 1 HTR2A
postsynaptic membrane 3 HTR2A, HTR3A, SLC6A4
Membrane raft 1 SLC6A4
Cell junction, focal adhesion 1 SLC6A4
focal adhesion 1 SLC6A4
basement membrane 1 ACHE
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Postsynaptic cell membrane 1 HTR3A
Cell projection, neuron projection 1 SLC6A4
neuron projection 3 HTR3A, PTGS2, SLC6A4
chromatin 1 AHR
blood microparticle 1 BCHE
serotonin-activated cation-selective channel complex 1 HTR3A
transmembrane transporter complex 1 HTR3A
Lipid-anchor, GPI-anchor 1 ACHE
Endomembrane system 2 SLC6A4, TAAR1
endosome lumen 1 INS
Membrane, caveola 1 HTR2A
aryl hydrocarbon receptor complex 1 AHR
cell body fiber 1 HTR2A
Cell projection, dendrite 2 HTR1A, HTR2A
side of membrane 1 ACHE
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 BCHE, INS, PTGS2
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
mitochondrial envelope 1 MAOB
Single-pass type IV membrane protein 2 MAOA, MAOB
nuclear envelope lumen 1 BCHE
neurofilament 1 HTR2A
synaptic cleft 1 ACHE
[Isoform H]: Cell membrane 1 ACHE
nuclear aryl hydrocarbon receptor complex 1 AHR
G protein-coupled serotonin receptor complex 2 HTR2A, HTR2C
serotonergic synapse 1 SLC6A4
cytosolic aryl hydrocarbon receptor complex 1 AHR


文献列表

  • Lei-Qi Liu, Jing-Ze Chen, Wu-Sheng Fu, Cui-Ying Tang. [Determination of amanita peptide and tryptamine toxins in wild mushrooms by high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2023 Nov; 41(11):976-985. doi: 10.3724/sp.j.1123.2023.07013. [PMID: 37968816]
  • Daijing Wei, Yun Yang, Ruiying Xi, Yunqing He, Ighodaro Igbe, Fei Wang, Guolin Zhang, Yinggang Luo. Hunteriasines A - D, tryptamine-derived alkaloids from Hunteria umbellata. Phytochemistry. 2023 Sep; 213(?):113752. doi: 10.1016/j.phytochem.2023.113752. [PMID: 37330032]
  • Lixiang Zhai, Haitao Xiao, Chengyuan Lin, Hoi Leong Xavier Wong, Yan Y Lam, Mengxue Gong, Guojun Wu, Ziwan Ning, Chunhua Huang, Yijing Zhang, Chao Yang, Jingyuan Luo, Lu Zhang, Ling Zhao, Chenhong Zhang, Johnson Yiu-Nam Lau, Aiping Lu, Lok-Ting Lau, Wei Jia, Liping Zhao, Zhao-Xiang Bian. Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome. Nature communications. 2023 Aug; 14(1):4986. doi: 10.1038/s41467-023-40552-y. [PMID: 37591886]
  • Jie Chen, Yueqi Zhang, Huanran Yin, Wei Liu, Xin Hu, Dongqin Li, Caixia Lan, Lifeng Gao, Zhonghu He, Fa Cui, Alisdair R Fernie, Wei Chen. The pathway of melatonin biosynthesis in common wheat (Triticum aestivum). Journal of pineal research. 2023 Mar; 74(2):e12841. doi: 10.1111/jpi.12841. [PMID: 36396897]
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  • Marcus Daniel Brandbjerg Bohn Lorensen, Nanna Bjarnholt, Benoit St-Pierre, Vincent Courdavault, Sarah Heinicke, Sarah O'Connor, Christian Janfelt. Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging. Phytochemistry. 2023 Feb; ?(?):113620. doi: 10.1016/j.phytochem.2023.113620. [PMID: 36863602]
  • Lea Wagmann, Sascha K Manier, Markus R Meyer. Can the Intake of a Synthetic Tryptamine be Detected Only by Blood Plasma Analysis? A Clinical Toxicology Case Involving 4-HO-MET. Journal of analytical toxicology. 2022 May; 46(5):567-572. doi: 10.1093/jat/bkab062. [PMID: 34100553]
  • Rajasree G Krishnan, Beena Saraswathyamma. Murexide-derived in vitro electrochemical sensor for the simultaneous determination of neurochemicals. Analytical and bioanalytical chemistry. 2021 Nov; 413(27):6803-6812. doi: 10.1007/s00216-021-03282-y. [PMID: 33774711]
  • Jiahui Shao, Yucong Li, Zunfeng Li, Zhihui Xu, Weibing Xun, Nan Zhang, Haichao Feng, Youzhi Miao, Qirong Shen, Ruifu Zhang. Participating mechanism of a major contributing gene ysnE for auxin biosynthesis in Bacillus amyloliquefaciens SQR9. Journal of basic microbiology. 2021 Jun; 61(6):569-575. doi: 10.1002/jobm.202100098. [PMID: 33914927]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Sascha K Manier, Christina Felske, Josef Zapp, Niels Eckstein, Markus R Meyer. Studies on the In Vitro and In Vivo Metabolic Fate of the New Psychoactive Substance N-Ethyl-N-Propyltryptamine for Analytical Purposes. Journal of analytical toxicology. 2021 Feb; 45(2):195-202. doi: 10.1093/jat/bkaa060. [PMID: 32507893]
  • Peisen Su, Lanfei Zhao, Wen Li, Jinxiao Zhao, Jun Yan, Xin Ma, Anfei Li, Hongwei Wang, Lingrang Kong. Integrated metabolo-transcriptomics and functional characterization reveals that the wheat auxin receptor TIR1 negatively regulates defense against Fusarium graminearum. Journal of integrative plant biology. 2021 Feb; 63(2):340-352. doi: 10.1111/jipb.12992. [PMID: 32678930]
  • Dagang Tian, Fang Yang, Yuqing Niu, Yan Lin, Zaijie Chen, Gang Li, Qiong Luo, Feng Wang, Mo Wang. Loss function of SL (sekiguchi lesion) in the rice cultivar Minghui 86 leads to enhanced resistance to (hemi)biotrophic pathogens. BMC plant biology. 2020 Nov; 20(1):507. doi: 10.1186/s12870-020-02724-6. [PMID: 33148178]
  • Analía A Gomez, Zareath P Terán Baptista, Tsvetelina Mandova, Angeliki Barouti, Marina Kritsanida, Raphaël Grougnet, Marta A Vattuone, Diego A Sampietro. Antifungal and antimycotoxigenic metabolites from native plants of northwest Argentina: isolation, identification and potential for control of Aspergillus species. Natural product research. 2020 Nov; 34(22):3299-3302. doi: 10.1080/14786419.2018.1560286. [PMID: 30663391]
  • Jyoti Singh Jadaun, Amit Kumar Kushwaha, Neelam S Sangwan, Lokesh Kumar Narnoliya, Smrati Mishra, Rajender Singh Sangwan. WRKY1-mediated regulation of tryptophan decarboxylase in tryptamine generation for withanamide production in Withania somnifera (Ashwagandha). Plant cell reports. 2020 Nov; 39(11):1443-1465. doi: 10.1007/s00299-020-02574-4. [PMID: 32789542]
  • Janis Fricke, Robert Kargbo, Lars Regestein, Claudius Lenz, Gundela Peschel, Miriam A Rosenbaum, Alexander Sherwood, Dirk Hoffmeister. Scalable Hybrid Synthetic/Biocatalytic Route to Psilocybin. Chemistry (Weinheim an der Bergstrasse, Germany). 2020 Jul; 26(37):8281-8285. doi: 10.1002/chem.202000134. [PMID: 32101345]
  • Hana Leontovyčová, Lucie Trdá, Petre Ivanov Dobrev, Vladimír Šašek, Elise Gay, Marie-Hélène Balesdent, Lenka Burketová. Auxin biosynthesis in the phytopathogenic fungus Leptosphaeria maculans is associated with enhanced transcription of indole-3-pyruvate decarboxylase LmIPDC2 and tryptophan aminotransferase LmTAM1. Research in microbiology. 2020 Jul; 171(5-6):174-184. doi: 10.1016/j.resmic.2020.05.001. [PMID: 32540203]
  • Xiaohong Fan, Junfang Li, Xuemei Deng, Yingmei Lu, Yiyue Feng, Shumeng Ma, Huaixiu Wen, Quanyi Zhao, Wen Tan, Tao Shi, Zhen Wang. Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation. European journal of medicinal chemistry. 2020 May; 193(?):112217. doi: 10.1016/j.ejmech.2020.112217. [PMID: 32182488]
  • Xiwen Tong, Yundan Wang, Pengcheng Yang, Chengshu Wang, Le Kang. Tryptamine accumulation caused by deletion of MrMao-1 in Metarhizium genome significantly enhances insecticidal virulence. PLoS genetics. 2020 04; 16(4):e1008675. doi: 10.1371/journal.pgen.1008675. [PMID: 32271756]
  • Brian G O'Flynn, Eric M Lewandowski, Karin Claire Prins, Gabriela Suarez, Angelica N McCaskey, Nasha M Rios-Guzman, Ryan L Anderson, Britney A Shepherd, Ioannis Gelis, James W Leahy, Yu Chen, David J Merkler. Characterization of Arylalkylamine N-Acyltransferase from Tribolium castaneum: An Investigation into a Potential Next-Generation Insecticide Target. ACS chemical biology. 2020 02; 15(2):513-523. doi: 10.1021/acschembio.9b00973. [PMID: 31967772]
  • Jakub Staroń, Rafał Kurczab, Dawid Warszycki, Grzegorz Satała, Martyna Krawczyk, Ryszard Bugno, Tomasz Lenda, Piotr Popik, Adam S Hogendorf, Agata Hogendorf, Krzysztof Dubiel, Mikołaj Matłoka, Rafał Moszczyński-Pętkowski, Jerzy Pieczykolan, Maciej Wieczorek, Paweł Zajdel, Andrzej J Bojarski. Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties. European journal of medicinal chemistry. 2020 Jan; 185(?):111857. doi: 10.1016/j.ejmech.2019.111857. [PMID: 31734022]
  • Yang Yu, Mei-Fen Bao, Jing Wu, Jing Chen, Yu-Rong Yang, Johann Schinnerl, Xiang-Hai Cai. Tabernabovines A-C: Three Monoterpenoid Indole Alkaloids from the Leaves of Tabernaemontana bovina. Organic letters. 2019 08; 21(15):5938-5942. doi: 10.1021/acs.orglett.9b02060. [PMID: 31294995]
  • Alma Vázquez-Luna, Fabio García-García, Diana I Caudillo Contreras, Eduardo Rivadeneyra-Domínguez, Rafael Díaz-Sobac. Effect of orange juice and tryptamine on the behavior and c-fos expression of Wistar rats. Metabolic brain disease. 2019 04; 34(2):519-525. doi: 10.1007/s11011-018-0365-5. [PMID: 30604026]
  • Mauro Commisso, Stefano Negri, Martino Bianconi, Sofia Gambini, Sara Avesani, Stefania Ceoldo, Linda Avesani, Flavia Guzzo. Untargeted and Targeted Metabolomics and Tryptophan Decarboxylase In Vivo Characterization Provide Novel Insight on the Development of Kiwifruits (Actinidia deliciosa). International journal of molecular sciences. 2019 Feb; 20(4):. doi: 10.3390/ijms20040897. [PMID: 30791398]
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  • Brian Torres, James S Tyler, Kenneth A Satyshur, Arnold E Ruoho. Human indole(ethyl)amine-N-methyltransferase (hINMT) catalyzed methylation of tryptamine, dimethylsulfide and dimethylselenide is enhanced under reducing conditions - A comparison between 254C and 254F, two common hINMT variants. PloS one. 2019; 14(7):e0219664. doi: 10.1371/journal.pone.0219664. [PMID: 31310642]
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  • Yogesh Bhattarai, Brianna B Williams, Eric J Battaglioli, Weston R Whitaker, Lisa Till, Madhusudan Grover, David R Linden, Yasutada Akiba, Karunya K Kandimalla, Nicholas C Zachos, Jonathan D Kaunitz, Justin L Sonnenburg, Michael A Fischbach, Gianrico Farrugia, Purna C Kashyap. Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. Cell host & microbe. 2018 06; 23(6):775-785.e5. doi: 10.1016/j.chom.2018.05.004. [PMID: 29902441]
  • Chris Dockendorff, Disha M Gandhi, Ian H Kimball, Kenneth S Eum, Radda Rusinova, Helgi I Ingólfsson, Ruchi Kapoor, Thasin Peyear, Matthew W Dodge, Stephen F Martin, Richard W Aldrich, Olaf S Andersen, Jon T Sack. Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels. Biochemistry. 2018 05; 57(18):2733-2743. doi: 10.1021/acs.biochem.8b00292. [PMID: 29616558]
  • Smitha Krishnan, Yufang Ding, Nima Saedi, Maria Choi, Gautham V Sridharan, David H Sherr, Martin L Yarmush, Robert C Alaniz, Arul Jayaraman, Kyongbum Lee. Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages. Cell reports. 2018 04; 23(4):1099-1111. doi: 10.1016/j.celrep.2018.03.109. [PMID: 29694888]
  • Jan Honegr, Rafael Dolezal, David Malinak, Marketa Benkova, Ondrej Soukup, Joyce S F D de Almeida, Tanos C C Franca, Kamil Kuca, Roman Prymula. Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery. Molecules (Basel, Switzerland). 2018 Jan; 23(1):. doi: 10.3390/molecules23010102. [PMID: 29300367]
  • Achim T Caspar, Jonas B Gaab, Julian A Michely, Simon D Brandt, Markus R Meyer, Hans H Maurer. Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn , and LC-HR-MS/MS. Drug testing and analysis. 2018 Jan; 10(1):184-195. doi: 10.1002/dta.2197. [PMID: 28342193]
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