2,2':5',2'-Terthiophene (BioDeep_00000000862)

 

Secondary id: BioDeep_00000861718, BioDeep_00001867560

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


2,2 inverted exclamation mark :5 inverted exclamation mark ,2 inverted exclamation mark inverted exclamation mark -Terthiophene

化学式: C12H8S3 (247.9788)
中文名称: 三噻吩, 2,2:5,2-三噻吩, α-三噻吩, 2,2′:5′,2′′-三噻吩
谱图信息: 最多检出来源 Homo sapiens(blood) 54.85%

分子结构信息

SMILES: C1(C2=CC=C(C3=CC=CS3)S2)=CC=CS1
InChI: InChI=1S/C12H8S3/c1-3-9(13-7-1)11-5-6-12(15-11)10-4-2-8-14-10/h1-8H

描述信息

2,2:5,2-terthiophene is a terthiophene.
2,2:5,2-Terthiophene is a natural product found in Schoenia cassiniana, Lawrencella rosea, and other organisms with data available.
D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
D010575 - Pesticides > D007306 - Insecticides
D003879 - Dermatologic Agents
D016573 - Agrochemicals
2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.
2,2':5',2''-Terthiophene (α-Terthiophene) is an oligomer of the heterocycle thiophene. 2,2':5',2''-Terthiophene has been employed as building block for the organic semi-conductor polythiophene.

同义名列表

44 个代谢物同义名

2,2 inverted exclamation mark :5 inverted exclamation mark ,2 inverted exclamation mark inverted exclamation mark -Terthiophene; InChI=1/C12H8S3/c1-3-9(13-7-1)11-5-6-12(15-11)10-4-2-8-14-10/h1-8; 2,2:5,2-Terthiophene (purified by sublimation); alpha-Terthienyl, 2,5-Di(2-thienyl)thiophene; 2,2:5,2-Terthiophene, (=alpha-Terthienyl); alpha-Terthienyl (2,2,5,2-Terthiophene); 5-(thiophen-2-yl)-2,2-bithiophene; 2,5-bis(thiophen-2-yl)thiophene; 2,2-Bithiophene, 5-(2-thienyl)-; 2,5-dithiophen-2-ylthiophene; 2,5-dithiophen-2-ylthiophen; 2,5-bis(2-thienyl)thiophene; 2,5-Di(2-thienyl)thiophene; 2,2:5,2-Terthiophene, 99\\%; .ALPHA.-TERTHIENYL [MI]; 2,2:5,2"-Terthiophene; 2,2:5,2-Terthiophene; 2,2,5,2-terthiophene; 2,2-5,2-Terthiophene; .alpha.-Terthiophene; 2,2:52-Terthiophene; 2,2:5,2-Terthienyl; TERTHIENYL, ALPHA-; 2,2,5,2-Terthienyl; .alpha.-Terthienyl; alpha-terthiophene; Maybridge1_007704; alpha-terthienyl; I+/--Terthienyl; UNII-0P77RAU2RR; Α-terthiophene; a-Terthiophene; .a.-Terthienyl; MEGxp0_001543; Trithiophene; terthiophene; Tox21_300648; Α-terthienyl; a-terthienyl; 0P77RAU2RR; C12H8S3; alpha-Terthienyl; α-?Terthiophene; 2,2':5',2''-Terthiophene



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

33 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AR, AXIN2, CAT, EGFR, G6PD, HPGDS, PNP, RHOA, SULT1A1, TUBB2B
Peripheral membrane protein 2 ACHE, G6PD
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 4 EGFR, HSP90B1, RHOA, TKT
Nucleus 9 ACHE, AR, AXIN2, EGFR, HSP90B1, KLK3, PCNA, RHOA, TUBB2B
cytosol 10 AR, AXIN2, CAT, G6PD, HPGDS, HSP90B1, PNP, RHOA, SULT1A1, TKT
nuclear body 2 PCNA, TKT
centrosome 2 AXIN2, PCNA
nucleoplasm 5 AR, HPGDS, PCNA, TKT, TMPRSS2
Cell membrane 5 ACHE, EGFR, RHOA, TKT, TMPRSS2
Lipid-anchor 1 RHOA
Cytoplasmic side 1 RHOA
Cleavage furrow 1 RHOA
lamellipodium 1 RHOA
ruffle membrane 2 EGFR, RHOA
Early endosome membrane 1 EGFR
Synapse 1 ACHE
cell cortex 1 RHOA
cell junction 2 EGFR, RHOA
cell surface 2 ACHE, EGFR
glutamatergic synapse 2 EGFR, RHOA
Golgi apparatus 1 ACHE
Golgi membrane 1 EGFR
lysosomal membrane 1 EGF
neuromuscular junction 1 ACHE
postsynapse 1 RHOA
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 G6PD
endosome 2 EGFR, RHOA
plasma membrane 9 ACHE, AR, AXIN2, EGF, EGFR, KLK3, RHOA, TKT, TMPRSS2
Membrane 8 ACHE, AR, CAT, EGF, EGFR, G6PD, HSP90B1, TMPRSS2
apical plasma membrane 2 EGFR, TKT
basolateral plasma membrane 1 EGFR
extracellular exosome 10 CAT, EGF, G6PD, HSP90B1, KLK3, PCNA, PNP, RHOA, TKT, TMPRSS2
endoplasmic reticulum 1 HSP90B1
extracellular space 5 ACHE, EGF, EGFR, KLK3, PNP
perinuclear region of cytoplasm 3 ACHE, EGFR, HSP90B1
Schaffer collateral - CA1 synapse 1 TUBB2B
mitochondrion 1 CAT
protein-containing complex 5 AR, CAT, EGFR, HSP90B1, KLK3
intracellular membrane-bounded organelle 3 CAT, G6PD, HPGDS
Single-pass type I membrane protein 2 EGFR, TKT
Secreted 2 ACHE, PNP
extracellular region 7 ACHE, CAT, EGF, HSP90B1, KLK3, PNP, TMPRSS2
cytoplasmic side of plasma membrane 2 G6PD, RHOA
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
centriolar satellite 1 G6PD
nuclear membrane 1 EGFR
actin cytoskeleton 1 TKT
dendritic spine 1 RHOA
beta-catenin destruction complex 1 AXIN2
microtubule cytoskeleton 1 TUBB2B
midbody 2 HSP90B1, RHOA
Single-pass type II membrane protein 1 TMPRSS2
vesicle 2 RHOA, TKT
Cell projection, lamellipodium 1 RHOA
Membrane raft 1 EGFR
Cytoplasm, cytoskeleton 1 TUBB2B
focal adhesion 5 CAT, EGFR, HSP90B1, RHOA, TKT
microtubule 1 TUBB2B
Peroxisome 2 CAT, TKT
basement membrane 1 ACHE
intracellular vesicle 1 EGFR
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 HSP90B1
secretory granule 1 KLK3
nuclear speck 1 AR
receptor complex 2 EGFR, TKT
chromatin 2 AR, PCNA
cell periphery 1 RHOA
mitotic spindle 1 TUBB2B
cytoskeleton 1 RHOA
nuclear replication fork 1 PCNA
chromosome, telomeric region 1 PCNA
Cytoplasm, cell cortex 1 RHOA
Lipid-anchor, GPI-anchor 1 ACHE
intercellular bridge 1 TUBB2B
Cell projection, dendrite 1 RHOA
Melanosome 1 HSP90B1
side of membrane 1 ACHE
replication fork 1 PCNA
sperm plasma membrane 1 HSP90B1
basal plasma membrane 1 EGFR
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 2 CAT, PNP
secretory granule lumen 2 CAT, PNP
secretory granule membrane 1 RHOA
endoplasmic reticulum lumen 1 HSP90B1
male germ cell nucleus 1 PCNA
platelet alpha granule lumen 1 EGF
nuclear lamina 1 PCNA
clathrin-coated endocytic vesicle membrane 2 EGF, EGFR
Sarcoplasmic reticulum lumen 1 HSP90B1
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 RHOA
[Transmembrane protease serine 2 catalytic chain]: Secreted 1 TMPRSS2
apical junction complex 1 RHOA
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
endocytic vesicle lumen 1 HSP90B1
catalase complex 1 CAT
endoplasmic reticulum chaperone complex 1 HSP90B1
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
[Isoform H]: Cell membrane 1 ACHE


文献列表

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  • Bin Zhao, Jingqian Huo, Ning Liu, Jinlin Zhang, Jingao Dong. Transketolase Is Identified as a Target of Herbicidal Substance α-Terthienyl by Proteomics. Toxins. 2018 01; 10(1):. doi: 10.3390/toxins10010041. [PMID: 29329271]
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