Bikaverin (BioDeep_00000008011)
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C20H14O8 (382.0688644)
中文名称:
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 1.79%
分子结构信息
SMILES: CC1=CC(=CC2=C1C(=O)C3=C(O2)C(=O)C4=C(C3=O)C(=CC(=C4O)OC)O)OC
InChI: InChI=1S/C20H14O8/c1-7-4-8(26-2)5-10-12(7)17(23)15-18(24)13-9(21)6-11(27-3)16(22)14(13)19(25)20(15)28-10/h4-6,21-22H,1-3H3
描述信息
A organic heterotetracyclic compound that is 10H-benzo[b]xanthene-7,10,12-trione substituted by hydroxy groups at positions 6 and 11, methoxy groups at positions 3 and 8 and a methyl group at position 1.
同义名列表
1 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:3096
- KEGG: C10306
- PubChem: 36433
- Metlin: METLIN68235
- ChEMBL: CHEMBL373432
- KNApSAcK: C00002798
- CAS: 33390-21-5
- PMhub: MS000090314
- PMhub: MS000021540
- MetaboLights: MTBLC3096
- PubChem: 12492
- 3DMET: B03726
- NIKKAJI: J19.756D
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 5507 Fusarium oxysporum: 10.1021/NP060394T
- 5127 Fusarium fujikuroi: 10.1007/BF02880192
- 5507 Fusarium oxysporum: 10.1021/NP060394T
- 5127 Fusarium fujikuroi: 10.1007/BF02880192
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Joseph E Spraker, Philipp Wiemann, Joshua A Baccile, Nandhitha Venkatesh, Julia Schumacher, Frank C Schroeder, Laura M Sanchez, Nancy P Keller. Conserved Responses in a War of Small Molecules between a Plant-Pathogenic Bacterium and Fungi.
mBio.
2018 05; 9(3):. doi:
10.1128/mbio.00820-18. [PMID: 29789359] - Jacqueline Edwards, Desmond Auer, Sri-Kanthi de Alwis, Brett Summerell, Takayuki Aoki, Robert H Proctor, Mark Busman, Kerry O'Donnell. Fusarium agapanthi sp. nov., a novel bikaverin and fusarubin-producing leaf and stem spot pathogen of Agapanthus praecox (African lily) from Australia and Italy.
Mycologia.
2016 09; 108(5):981-992. doi:
10.3852/15-333. [PMID: 27474520] - D Nirmaladevi, M Venkataramana, S Chandranayaka, A Ramesha, N M Jameel, C Srinivas. Neuroprotective effects of bikaverin on H2O2-induced oxidative stress mediated neuronal damage in SH-SY5Y cell line.
Cellular and molecular neurobiology.
2014 Oct; 34(7):973-85. doi:
10.1007/s10571-014-0073-6. [PMID: 24848007] - Radhika Deshmukh, Hemant J Purohit. siRNA mediated gene silencing in Fusarium sp. HKF15 for overproduction of bikaverin.
Bioresource technology.
2014 Apr; 157(?):368-71. doi:
10.1016/j.biortech.2014.02.057. [PMID: 24636053] - I Lazzaro, M Busman, P Battilani, R A E Butchko. FUM and BIK gene expression contribute to describe fumonisin and bikaverin synthesis in Fusarium verticillioides.
International journal of food microbiology.
2012 Nov; 160(2):94-8. doi:
10.1016/j.ijfoodmicro.2012.10.004. [PMID: 23177047] - M Busman, R A E Butchko, R H Proctor. LC-MS/MS method for the determination of the fungal pigment bikaverin in maize kernels as an indicator of ear rot.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2012; 29(11):1736-42. doi:
10.1080/19440049.2012.704528. [PMID: 22845490] - Gábor Kohut, Brigitta Oláh, Attila L Adám, Jorge García-Martínez, László Hornok. Adenylyl cyclase regulates heavy metal sensitivity, bikaverin production and plant tissue colonization in Fusarium proliferatum.
Journal of basic microbiology.
2010 Feb; 50(1):59-71. doi:
10.1002/jobm.200900113. [PMID: 20082366] - Naoko Nishimura, Masayuki Takai, Eisaku Yamamoto, Keiji Hasumi. Purpurin as a specific inhibitor of spermidine-induced autoactivation of the protease plasma hyaluronan-binding protein.
Biological & pharmaceutical bulletin.
2010; 33(8):1430-3. doi:
10.1248/bpb.33.1430. [PMID: 20686243] - Yoon-E Choi, Jillian A Brown, Courtney B Williams, Lorena L Canales, Won-Bo Shim. GAC1, a gene encoding a putative GTPase-activating protein, regulates bikaverin biosynthesis in Fusarium verticillioides.
Mycologia.
2008 Sep; 100(5):701-9. doi:
10.3852/08-015. [PMID: 18959154] - S W Son, H Y Kim, G J Choi, H K Lim, K S Jang, S O Lee, S Lee, N D Sung, J-C Kim. Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans.
Journal of applied microbiology.
2008 Mar; 104(3):692-8. doi:
10.1111/j.1365-2672.2007.03581.x. [PMID: 17927749] - Alois A Bell, Michael H Wheeler, Jinggao Liu, Robert D Stipanovic, Lorraine S Puckhaber, Heather Orta. United States Department of Agriculture-Agricultural Research Service studies on polyketide toxins of Fusarium oxysporum f sp vasinfectum: potential targets for disease control.
Pest management science.
2003 Jun; 59(6-7):736-47. doi:
10.1002/ps.713. [PMID: 12846324] - D Latus-Zietkiewicz, J Chelkowski, E Foremska, P Goliński, J Grabarkiewicz-Szczesna, M Kostecki, M Lew, J Perkowski, M Piasecki, M Wiewiórowska, K Szebiotko. Biosynthesis of gibberellic acid (GA3) and mycotoxins by F. moniliforme sheldon and other species of Liseola section.
Natural toxins.
1996; 4(5):228-33. doi:
10.1002/(sici)(1996)4:5<228::aid-nt5>3.0.co;2-g. [PMID: 8946398]